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Search Results for " non-toxic "
Targets Recommended: c-Met/HGFR

50

抑制剂 & 化合物

8

天然产物

4

重组蛋白

3

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T25492 Hepln-13

Hepln 13,Hepln13

c-Met/HGFR Tyrosine Kinase/Adaptors
Hepln-13 是具有口服活性的Hepsin 抑制剂(IC50:0.33 µM)。它可用于研究转移性前列腺癌。
TP1253 Argireline

六胜肽,Acetyl hexapeptide-3,阿基瑞林

Others Others
Argireline (Acetyl hexapeptide-3) 是可渗透皮肤的、无毒的抗皱肽。它对神经肌肉接头处依赖 Ca2+的神经递质释放具有显著的抑制作用。它具有抗皱和抗衰老的活性。
T6456 CRT0044876

NSC 69877,7-NO2-ICA,7-硝基吲哚-2-甲酸,NSC 69877,7-Nitroindole-2-Carboxylic Acid

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
CRT0044876 (7-NO2-ICA) 是一种高选择性的嘌呤/嘧啶核苷核酸内切酶 1 抑制剂,IC50约为 3 μM。它也是 APE1 所属的核酸外切酶 III 家族的特异性抑制剂,可抑制 APE1 的 AP 内切酶、3′-磷酸二酯酶和 3′-磷酸酶活性,可增强几种 DNA 碱基靶向化合物的细胞毒性。
T30582 BRD56491

BRD-56491,BRD 56491

Others Others
BRD56491 is a non-toxic reactive oxygen species (ROS) enhancer that strongly elevates markers of oxidative stress without causing cell death.
T5314 pyridoxal isonicotinoyl hydrazone

吡哆醛异烟酰肼,PIH

Others Others
pyridoxal isonicotinoyl hydrazone (PIH) 是亲脂的三价铁螯合剂,具有高铁螯合特性。
T15379 GGsTop

Nahlsgen

Others Others
GGsTop is a non-toxic and irreversible inhibitor of γ glutamyl transpeptidase (GGT) (Ki: 170 μM for Human GGT). GGsTop protects hepatic ischemia-reperfusion injury in the rat model. GGsTop shows Kons of 150±10 and 51±3 /(M·s) against E.coli GGT and human GGT, respectively.
T19232 CMC-Na (Viscosity:800-1200 mPa.s)

羧甲基纤维素钠,Sodium carboxymethyl cellulose,CMC-Na (Viscosity:800-1200 mPa.s)

Others Others
Sodium carboxymethyl cellulose (CMC-Na) (Viscosity:800-1200 mPa.s) 是一种水溶性纤维素,常用作动物实验的助溶剂,对动物基本没有毒性。
T8669 BTDA

3,3',4,4'-Benzophenonetetracarboxylic dianhydride

Others Others
3,3',4,4'-Benzophenonetetracarboxylic dianhydride 是一种化合物,用于生产聚酰亚胺薄膜和粘合剂的聚酰亚胺前体。它是一种无毒材料,对人体健康没有已知的不良影响。
T0914 Metacetamol

酰胺苯酚,3-Acetamidophenol

Others Others
Metacetamol (3-Acetamidophenol) 是对乙酰氨基酚的衍生物,为其无毒区域异构体,是一种非处方镇痛剂和解热剂,也可用作有机合成中间体。
T14922 Cefodizime

Antibacterial; Antibiotic Microbiology/Virology
Cefodizime 是一种新型头孢菌素抗生素,具有广泛的生物活性。Cefodizime 对肾脏没有毒性且具有良好的耐受性和免疫调节活性,具有抗菌活性,可用于研究呼吸系统和泌尿系统的严重感染。
T14319 Aripiprazole Lauroxil

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Aripiprazole lauroxil 是一种长效注射剂 (LAI) 的抗精神病药物,是阿立哌唑的 N-酰氧基甲基前药形式。它能够被体内酯酶裂解为 N-羟甲基阿立哌唑(月桂酸),再裂解为阿立哌唑,无毒性。
T15602 ITX3

Others; Rho Cell Cycle/Checkpoint; Others
ITX3 是特异的、无毒的、有活性的、具有选择性的TrioN RhoGEF 抑制剂,IC50 值为 76 μM。 ITX3具有抗癌作用,能抑制trion 介导的GTP 在RhoG 和Rac1上的交换,抑制ngf 介导的PC12细胞神经突的生长和trion 诱导的REF52成纤维细胞结构的形成。
T38063 N-Acetyl lysyltyrosylcysteine amide

Glutathione Peroxidase Metabolism
N-Acetyl lysyltyrosylcysteine amide 是一种无毒的髓过氧化物酶 (MPO) 三肽抑制剂,具有有效性,可逆性和特异性。N-Acetyl lysyltyrosylcysteine amide 在体内可有效抑制 MPO 产生。N-Acetyl lysyltyrosylcysteine amide 减轻中风后大脑的神经元损伤,并保留脑组织和神经功能。N-Acetyl lysyltyrosylcysteine amide 抑制MPO依赖性次氯酸 (HOCl) 的生成,蛋白质硝化和 LDL 氧化。N-Acetyl lysyltyrosylcysteine amide 可用于研究支气管发育不良。
T33923 Pentyl rhamnoside

Selectiose

Others Others
Pentyl rhamnoside is a new non-toxic cosurfactant to formulate microemulsions.
T34391 Rosmarinine

Others Others
Rosmarinine is a non-toxic pyrrolizidine alkaloid.
T16082 Mivotilate

YH439

Others Others
Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.
T22255 Amastatin

Others Others
Amastatin is a non-toxic inhibitor of aminopeptidase A and leucine aminopeptidase, and its Ki for aminopeptidase A is 1 µM .
T33388 Mimosine methyl ester

L-Mimosine methyl ester

Others Others
Mimosine methyl ester is a toxic non-protein amino acid chemically similar to tyrosine, that was first isolated from Mimosa pudica.
T71501 GBS-149

Others Others
GBS-149 is a novel non-toxic and mammalian-specific LINE-1 inhibitor.
T31437 Dicobalt edetate

Ba-2724,Ba2724,Ba 2724,Kelocyanor

Others Others
Cobalt edylic acid is a cobalt compound whose mechanism is that cyanide binds cobalt to form a relatively non-toxic complex.
T11051 DIQ3

Others Others
DIQ3 is non-toxic to normal human cell lines and is an effective anti-cancer agent.
T30581 BRD5459

BRD-5459,BRD 5459

Others Others
BRD5459 is a kind of reactive oxygen species enhancer that is non-toxic or leads to genotype selective cell death. Brd5459 can selectively kill cancer cells in various in vitro and in vivo models.
T28110 MRZ-99030

EG 030,EG030,EG-030,MRZ 99030

Others Others
MRZ-99030 is an Aβ aggregation modulator. MRZ-99030 triggers a non-amyloidogenic aggregation pathway, thereby reducing the amount of intermediate toxic soluble oligomeric Aβ species.
T61470 NMDA receptor antagonist 5

Others Others
NMDA receptor antagonist 5 (Compound 10e), a potent and non-toxic NMDA receptor antagonist, exhibits brain permeability. It is of significance in studying neurological disorders [1].
T13609L Chlorazanil

Others Others
Chlorazanil 是一种三嗪衍生物,也是一种口服有效的新型非毒性利尿剂,可以阻止钠和氯在远曲小管的吸收。
T60855 Elastase-IN-1

Others Others
Elastase-IN-1 (Compound Q11) 是无毒的弹性蛋白酶抑制剂,IC50值为 0.897 μM。
T3694L Tebanicline tosylate

Others Others
Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine. Like epibatidine, tebanicline showed potent analgesic activity against neuropat
T73356 Ac32Az19

Others Others
Ac32Az19 是一种有效、无毒、高选择性的 BCRP 抑制剂,在BCRP 过度表达的HEK293/R2细胞中,EC50值为13 nM。
T39322 Temporin A

Temporin A, a short alpha-helical antimicrobial peptide derived from the skin of Rana temporaria, exhibits a wide-ranging efficacy against Gram-positive bacteria. It directly interacts with the cell membrane of microorganisms and remains non-toxic to erythrocytes at antimicrobial concentrations. Additionally, Temporin A demonstrates antifungal properties against yeast-like Candida albicans.
T74526 Antifungal agent 29

Others Others
Antifungal agent 29 (化合物 9d) 是一种有效的、选择性的、无毒的抗真菌剂。Antifungal agent 29 对新隐球菌具有抗真菌活性 (MIC≤ 0.23 μM)。
T23207 Q-VD(OMe)-OPh

Others Others
Q-VD-OPh (quinolyl-valyl-O-methylaspartyl-[-2,6-difluorophenoxy]-methyl ketone) is a broad-spectrum caspase inhibitor, provides a cost-effective, non-toxic, and highly specific means of apoptotic inhibition and provides new insight into the design of new
T62697 BuChE-IN-3

Others Others
BuChE-IN-3 (Compound C4) 是一种 BuChE 的有效抑制剂 (IC50: 8.3 nM)。BuChE-IN-3 具有温和的抗氧化能力、无毒、亲脂性和神经保护效果。
T34029 Phosmet oxon

R-1571,R 1571,ENT 25707,ENT-25707,R1571

Others Others
Phosmet oxon is a toxic metabolite of phosmet, a phthalimide-derived, non-systemic, organophosphate insecticide used on plants and animals. It is mainly used on apple trees for control of codling moth, though it is also used on a wide range of fruit crops
T76244 Amp1EP9

Amp1EP9为一抗菌肽,作为开发有效无毒抗菌活性分子的强大工具,具备针对多重耐药细菌感染进行研究的潜力。
T63472 HDAC6-IN-4

Others Others
HDAC6-IN-4 (C10) 是一种口服具有活力的、高度选择性的、有效的、无明显毒性的 HDAC6 抑制剂 (IC50: 23 nM)。HDAC6-IN-4 能够诱导肿瘤细胞凋亡 (apoptosis),表现出高效的抗肿瘤效果。
T61462 EV-A71-IN-1

Others Others
EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP1 protein and the host receptor hSCARB2. It displays broad-spectrum antiviral activity against various human enteroviruses, while being non-toxic to human cells (CC50 > 56.2 μM) [1].
T63628 AChE-IN-19

Others Others
AChE-IN-19 是 AChE 的高效抑制剂 (IC50: 0.56 μM),对 Aβ 聚集也表现出抑制作用。AChE-IN-19 表现出神经保护作用,对 SH-SY5Y 细胞几乎没有毒性。AChE-IN-19 能够用于研究阿尔兹海默症。
T40341 SARS-CoV-2-IN-11

Others Others
SARS-CoV-2-IN-11 is a highly potent and non-toxic inhibitor of the 3C-like protease (3CLpro) of SARS-CoV-2, demonstrating IC50 and EC50 values of 0.17 nM and 1.45 nM, respectively. This compound targets the essential viral replication enzyme, 3CLpro, making it an attractive candidate for intervention strategies. SARS-CoV-2-IN-11 holds significant promise in the development of specific antivirals against SARS-CoV-2.
T74494 Antitumor agent-63

Others Others
Antitumor agent-63(Compound 40),一种20 (S)-O-linked camptothecin (CPT) 糖复合物,作为抗肿瘤剂,对正常细胞展现出无毒性。该化合物表现出高稳定性和低topoisomeraseI (Topo I)直接抑制活性。
T78305 Briquilimab

JSP-191

Briquilimab (JSP-191) 是针对 CD117 (c-Kit) 的无毒人源化单克隆抗体,用于消耗造血干细胞 (HSC)。它被应用于重度联合免疫缺陷 (SCID) 治疗中,以清空宿主骨髓生态位,为供体造血干细胞移植及免疫重建创造条件。
T82388 Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Caspase Apoptosis; Proteases/Proteasome
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone 是一种细胞渗透性且无毒的抑制剂,它能与活化的caspase-3在凋亡细胞内不可逆结合。该抑制剂的荧光强度可通过流式细胞仪、微孔板读数器或荧光显微镜检测。
T40340 SARS-CoV-2-IN-10

Others Others
SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is a critical enzyme for viral replication and serves as an ideal target for intervention. By targeting the SARS-CoV-2 3CL protease, SARS-CoV-2-IN-10 has the potential to facilitate the development of effective antiviral drugs specific to SARS-CoV-2.
T79559 Mtb-IN-4

Others Others
Mtb-IN-4(化合物17h)是一种异恶唑类化合物,显示出针对结核分枝杆菌(Mtb)的抗活性,其IC50值为0.70 μM。它能阻断巨噬细胞内Mtb的呼吸和生物膜形成,并可以增强抗生素异烟肼(INH)对耐INH Mtb突变体的抑制效果。
T36475 TunR2

Others Others
TunR2 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtiliswhen used at a concentration of 0.4 μg/ml. Unlike tunicamycin, TunR2 is non-toxic toS. cerevisiae(MIC = >10 μg/ml) and does not inhibit glycosylation in a protein N-glycosylation assay. TunR2 also has reduced antiproliferative activity against MDA-MB-231 and CHO cells compared wi...
T11896 LV-320

Cysteine Protease Proteases/Proteasome
LV-320 是一种有效且非竞争性的ATG4B 抑制剂,其IC50值为 24.5 μM,Kd 值为 16 μM。 LV-320 抑制ATG4B 的酶促活性,阻断细胞自噬,并且稳定无毒,在体内具有活性。
T78964 Antileishmanial agent-17

Parasite Microbiology/Virology
Antileishmanial agent-17是香豆素杂化化合物,展现出优越的抗利什曼原虫活性(IC50<0.78 μM),同时对VERO细胞具备安全性。该化合物通过抑制叶酸代谢途径发挥效用,且在对抗利什曼原虫不同生长阶段表现显著,其IC50值分别对前鞭毛体为0.40 μM,对无鞭毛体为0.68 μM。
T69657 GS-441524 HCl

Others Others
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM.. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations ...
T63735 SP inhibitor 1

Others Others
SP inhibitor 1 是体外无毒浓度 (0.3250<5.98 μM) 的 SARS-CoV-2 复制抑制剂。SP inhibitor 1 是 SARS-CoV-2 刺突蛋白 (SP) 的选择性抑制剂,能够作用于 SP 蛋白 (IC50: 3.26 μM)、Mpro 蛋白 (IC50>25 μM)和 PLpro 蛋白 (IC50>25 μM),具有细胞抗病毒作用。
T62729 MS31 trihydrochloride

Others Others
MS31 trihydrochloride 是一种选择性的、高亲和性的、片段样的甲基赖氨酸读写蛋白 spindlin 1 (SPIN1) 抑制剂。MS31 trihydrochloride 有效破坏 SPIN1 与 H3K4me3 蛋白互相作用 (IC50: 77 nM,AlphaLISA;243 nM,FP),选择性结合 SPIN1 的 Tudor 结构域 II (Kd: 91 nM)。MS31 trihydrochloride 对含三甲基赖氨酸肽与 SPIN1 的结合具有有效抑制作用,对非肿瘤性细胞没有毒性。
T66029 3,4-Dehydro-L-proline

The leguminous shrub,Leucaena leucocephala(Leucaena) is wide‐spread in tropical and subtropical agricultural systems and provides a ready source of protein for livestock. However, the presence of mimosine, a non‐protein, amino acid comprising about 12% of the dry matter in growing tips ofLeucaena, is toxic to animals. Mimosine is degraded rapidly in the rumen to produce 3,4‐dihydroxypyridine (3,4‐DHP) and 2,3‐dihydroxypyridine (2,3‐DHP), both of which remain toxic to animals[1]. 3,4-DHP, as a de...

化合物

Hepln-13
Cat.No: T25492
Synonym: Hepln 13,Hepln13
Target: c-Met/HGFR
Argireline
Cat.No: TP1253
Synonym: 六胜肽,Acetyl hexapeptide-3,阿基瑞林
Target: Others
CRT0044876
Cat.No: T6456
Synonym: NSC 69877,7-NO2-ICA,7-硝基吲哚-2-甲酸,NSC 69877,7-Nitroindole-2-Carboxylic Acid
Target: DNA/RNA Synthesis
BRD56491
Cat.No: T30582
Synonym: BRD-56491,BRD 56491
Target: Others
pyridoxal isonicotinoyl hydrazone
Cat.No: T5314
Synonym: 吡哆醛异烟酰肼,PIH
Target: Others
GGsTop
Cat.No: T15379
Synonym: Nahlsgen
Target: Others
CMC-Na (Viscosity:800-1200 mPa.s)
Cat.No: T19232
Synonym: 羧甲基纤维素钠,Sodium carboxymethyl cellulose,CMC-Na (Viscosity:800-1200 mPa.s)
Target: Others
BTDA
Cat.No: T8669
Synonym: 3,3',4,4'-Benzophenonetetracarboxylic dianhydride
Target: Others
Metacetamol
Cat.No: T0914
Synonym: 酰胺苯酚,3-Acetamidophenol
Target: Others
Cefodizime
Cat.No: T14922
Synonym:
Target: Antibacterial, Antibiotic
Aripiprazole Lauroxil
Cat.No: T14319
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
ITX3
Cat.No: T15602
Synonym:
Target: Others, Rho
N-Acetyl lysyltyrosylcysteine amide
Cat.No: T38063
Synonym:
Target: Glutathione Peroxidase
Pentyl rhamnoside
Cat.No: T33923
Synonym: Selectiose
Target: Others
Rosmarinine
Cat.No: T34391
Synonym:
Target: Others
Mivotilate
Cat.No: T16082
Synonym: YH439
Target: Others
Amastatin
Cat.No: T22255
Synonym:
Target: Others
Mimosine methyl ester
Cat.No: T33388
Synonym: L-Mimosine methyl ester
Target: Others
GBS-149
Cat.No: T71501
Synonym:
Target: Others
Dicobalt edetate
Cat.No: T31437
Synonym: Ba-2724,Ba2724,Ba 2724,Kelocyanor
Target: Others
DIQ3
Cat.No: T11051
Synonym:
Target: Others
BRD5459
Cat.No: T30581
Synonym: BRD-5459,BRD 5459
Target: Others
MRZ-99030
Cat.No: T28110
Synonym: EG 030,EG030,EG-030,MRZ 99030
Target: Others
NMDA receptor antagonist 5
Cat.No: T61470
Synonym:
Target: Others
Chlorazanil
Cat.No: T13609L
Synonym:
Target: Others
Elastase-IN-1
Cat.No: T60855
Synonym:
Target: Others
Tebanicline tosylate
Cat.No: T3694L
Synonym:
Target: Others
Ac32Az19
Cat.No: T73356
Synonym:
Target: Others
Temporin A
Cat.No: T39322
Synonym:
Target:
Antifungal agent 29
Cat.No: T74526
Synonym:
Target: Others
Q-VD(OMe)-OPh
Cat.No: T23207
Synonym:
Target: Others
BuChE-IN-3
Cat.No: T62697
Synonym:
Target: Others
Phosmet oxon
Cat.No: T34029
Synonym: R-1571,R 1571,ENT 25707,ENT-25707,R1571
Target: Others
Amp1EP9
Cat.No: T76244
Synonym:
Target:
HDAC6-IN-4
Cat.No: T63472
Synonym:
Target: Others
EV-A71-IN-1
Cat.No: T61462
Synonym:
Target: Others
AChE-IN-19
Cat.No: T63628
Synonym:
Target: Others
SARS-CoV-2-IN-11
Cat.No: T40341
Synonym:
Target: Others
Antitumor agent-63
Cat.No: T74494
Synonym:
Target: Others
Briquilimab
Cat.No: T78305
Synonym: JSP-191
Target:
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone
Cat.No: T82388
Synonym:
Target: Caspase
SARS-CoV-2-IN-10
Cat.No: T40340
Synonym:
Target: Others
Mtb-IN-4
Cat.No: T79559
Synonym:
Target: Others
TunR2
Cat.No: T36475
Synonym:
Target: Others
LV-320
Cat.No: T11896
Synonym:
Target: Cysteine Protease
Antileishmanial agent-17
Cat.No: T78964
Synonym:
Target: Parasite
GS-441524 HCl
Cat.No: T69657
Synonym:
Target: Others
SP inhibitor 1
Cat.No: T63735
Synonym:
Target: Others
MS31 trihydrochloride
Cat.No: T62729
Synonym:
Target: Others
3,4-Dehydro-L-proline
Cat.No: T66029
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T5757 Loganetin

Antibacterial Microbiology/Virology
Loganetin 是无毒的天然产物,来源于Cornus officinalis Sieb. et Zucc.,可用于耐多药革兰氏阴性菌感染的研究。
T5279 Ethylmalonic acid

alpha-Carboxybutyrate,2-Ethylmalonic acid,乙基丙二酸

Others; Endogenous Metabolite Metabolism; Others
Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。
T4S1521 1,4-Dicaffeoylquinic acid

1,4-二咖啡酰奎宁酸,洋蓟素

HIV Protease Microbiology/Virology; Proteases/Proteasome
1,4-Dicaffeoylquinic acid 是一种苯丙素类物质,从苍耳子中获得,可以减少 LPS 诱导的 TNF-α 的生成,具有抗炎活性。
T3321 Oleanonic acid

3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,齐墩果酮酸,3-Ketooleanolic Acid

HIV Protease Microbiology/Virology; Proteases/Proteasome
Oleanonic acid (3-Ketooleanolic Acid) 是一种三萜,可以抑制 HIV-1 对细胞的感染。它具有保肝作用,并具有抗肿瘤和抗病毒特性。
TN1704 Glycyrrhetic acid 3-O-β-D-glucuronide

Glycyrrhetic acid 3-O-mono-beta-D-glucuronide,单葡萄糖醛酸甘草次酸

Others Others
Glycyrrhetic acid 3-O-mono-beta-D-glucuronide 是从甘草中分离出的甘草酸 3-O-β-D-葡萄糖醛酸,是甘草甜素的重要衍生物。它具有抗过敏活性,可作为甜味剂。
T4776 Glycerol

Glycerin,甘油

Endogenous Metabolite Metabolism
Glycerol 是甘油三酯(即脂肪和油)和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
T15703 Lactimidomycin

Others Others
Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferative effect on tumor cell lines. It i
T75447 Asperaculane B

Others Others
Asperaculane B,一种真菌代谢产物,以IC50 7.89 µM抗恶性疟原虫传播,同时以IC50 3 µM抑制无性恶性疟原虫的发育,对人类细胞无毒。

天然产物

Loganetin
Cat.No: T5757
Synonym:
Target: Antibacterial
Ethylmalonic acid
Cat.No: T5279
Synonym: alpha-Carboxybutyrate,2-Ethylmalonic acid,乙基丙二酸
Target: Others, Endogenous Metabolite
1,4-Dicaffeoylquinic acid
Cat.No: T4S1521
Synonym: 1,4-二咖啡酰奎宁酸,洋蓟素
Target: HIV Protease
Oleanonic acid
Cat.No: T3321
Synonym: 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,齐墩果酮酸,3-Ketooleanolic Acid
Target: HIV Protease
Glycyrrhetic acid 3-O-β-D-glucuronide
Cat.No: TN1704
Synonym: Glycyrrhetic acid 3-O-mono-beta-D-glucuronide,单葡萄糖醛酸甘草次酸
Target: Others
Glycerol
Cat.No: T4776
Synonym: Glycerin,甘油
Target: Endogenous Metabolite
Lactimidomycin
Cat.No: T15703
Synonym:
Target: Others
Asperaculane B
Cat.No: T75447
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00771 Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)

Ferritin-2, chloroplastic,SFerH-2

Glycine max E. coli
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
TMPJ-00761 FTH Protein, Human, Recombinant (His)

FTHL6,Cell proliferation-inducing gene 15 protein,Ferritin h...

Human E. coli
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of...
TMPY-02711 Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant

FHC,FTHL6,FTH,PIG15,PLIF,ferritin, heavy polypeptide 1,HFE5

Human E. coli
FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative dis...
TMPY-02299 ALDH3A1 Protein, Human, Recombinant (His)

ALDHIII,aldehyde dehydrogenase 3 family, member A1,ALDH3

Human Baculovirus Insect Cells
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi...

重组蛋白

Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)
Cat.No: TMPH-00771
Species: Glycine max
Expression System: E. coli
FTH Protein, Human, Recombinant (His)
Cat.No: TMPJ-00761
Species: Human
Expression System: E. coli
Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant
Cat.No: TMPY-02711
Species: Human
Expression System: E. coli
ALDH3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02299
Species: Human
Expression System: Baculovirus Insect Cells
Cat. No. Product Name Target Signaling Pathways
T35521 Aflatoxin G2-13C17

Aflatoxin G2-13C17

Aflatoxin G2-13C17is intended for use as an internal standard for the quantification of aflatoxin G2by GC- or LC-MS. Aflatoxin G2is a mycotoxin that has been found inAspergillus.1It is lethal to ducklings (LD50= 2.83 mg/kg) but is non-toxic to rats when administered at a dose of 200 mg/kg.2 1.Bennett, J.W., and Klich, M.MycotoxinsClin. Microbiol. Rev.16(3)497-516(2003) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins a...
T11934 Macitentan-d4

Macitentan D4,ACT-064992 D4

Endothelin Receptor GPCR/G Protein
Macitentan-d4 (ACT-064992 D4) 是一种 Macitentan 氘代物,可被当作非多肽 ETA 和 ETB  (内皮素受体)双拮抗剂。Macitentan-d4 比 Macitentan 毒性更低,半衰期更长,可用于研究由内皮素受体介导介导的疾病。
TMID-0097 Ethyl-d5-malonic Acid

Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。

同位素标记化合物

Aflatoxin G2-13C17
Cat.No: T35521
Synonym: Aflatoxin G2-13C17
Target:
Macitentan-d4
Cat.No: T11934
Synonym: Macitentan D4,ACT-064992 D4
Target: Endothelin Receptor
Ethyl-d5-malonic Acid
Cat.No: TMID-0097
Synonym:
Target:
TargetMol Loading
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