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102
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T73610 |
Lipoprotein lipase
|
Others | Others |
Lipoprotein lipase 是来自于脂肪组织、心肌和骨骼肌、胰岛和巨噬细胞的多功能酶。Lipoprotein lipase 促进正常脂蛋白代谢、组织特异性底物的输送和利用。Lipoprotein lipase 催化脂质在血液循环的限速步骤。 | |||
T2499 |
Torcetrapib
CP-529414,托彻普 |
CETP | Metabolism |
是胆固醇酯转移蛋白 (CETP) 选择性抑制剂。根据人血浆的抑制曲线,Torcetrapib (CP-529414) 对CETP 的最有效浓度为 37 nM。 | |||
T7832 |
Ibrolipim
NO-1886 |
LPL Receptor | GPCR/G Protein |
Ibrolipim (NO-1886) 是口服具有活力的脂蛋白脂肪酶 (LPL) 激活剂。它能够降低血浆甘油三酸酯,增加高密度脂蛋白胆固醇水平,具有肾保护和降血脂的作用。 | |||
T1676 |
Rosuvastatin
罗伐他汀,ZD 4522,瑞舒伐他汀 |
Potassium Channel; HMG-CoA Reductase; Autophagy | Autophagy; Membrane transporter/Ion channel; Metabolism |
Rosuvastatin (ZD 4522) 是一种抗血脂药,可竞争性抑制羟甲基戊二酰辅酶 A 还原酶,用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,IC50为 195 nM,延迟心脏复极化,延长动作电位持续时间和校正 QT 间期间隔。 | |||
T1510 |
Rosuvastatin calcium
ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙 |
Potassium Channel; HMG-CoA Reductase; Autophagy | Autophagy; Membrane transporter/Ion channel; Metabolism |
Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂,具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用,还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,延迟心脏复极化,来延长动作电位持续时间和校正 QT 间期间隔。 | |||
T1415 |
Gemfibrozil
吉非罗齐,CI-719,Jezil,Decrelip,Lopid |
P450; Adrenergic Receptor; PPAR | DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience |
Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。 | |||
T11386L |
Gemcabene
PD-72953 |
Others | Others |
Gemcabene (PD-72953) 是一种具有抗炎活性的降脂剂。 Gemcabene 降低低密度脂蛋白胆固醇和甘油三酯,提高高密度脂蛋白胆固醇,并降低促炎急性期蛋白、C 反应蛋白。 | |||
T13601 |
CDD3506
1-TRITYL-1H-IMIDAZOL-4-AMINE |
P450 | Metabolism |
CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) 能够诱导肝CYP3A 的活动,增强高密度脂蛋白胆固醇的水平。 | |||
T11874 |
Lp-PLA2-IN-3
|
Phospholipase | Metabolism |
Lp-PLA2-IN-3 是一种强效且具有口服生物活性的脂蛋白相关磷脂酶 A2(Lp-PLA2)抑制剂,对重组人 Lp-PLA2 具有抑制作用,IC50 值为 14 nM。 | |||
T25701 |
Levosemotiadil
SD 3212,SA 3212 |
LDL; Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Levosemotiadil(SA 3212) 是一种新型钙拮抗剂,是一种非常有效的低密度脂蛋白氧化抑制剂。Levosemotiadil 可用于预防致死性心律失常。 | |||
T6109 |
Darapladib
达拉地,SB-480848 |
Phospholipase | Metabolism |
Darapladib (SB-480848) 是脂蛋白相关磷脂酶A2 (Lp-PLA2) 抑制剂,IC50=0.25 nM。 | |||
T1771 |
Ro 48-8071 fumarate
|
Others | Others |
Ro 48-8071 fumarate 是一种氧化鲨烯环化酶抑制剂(IC50:6.5 nM)。 | |||
T19861 |
Niceritrol
Perycit,Cardiolipol,戊四烟酯,Bufor |
Others | Others |
Niceritrol (Cardiolipol) 是一种烟酸酯,可降低总血浆以及 VLD 和 LD 脂蛋白部分中的胆固醇和甘油三酯。 | |||
T30577 |
BRD0418
BRD 0418,BRD-0418 |
Others | Others |
BRD0418作为 TRIB1表达的上调因子,导致肝脏脂蛋白代谢从脂肪生成到清除的重新编程。 | |||
T16751 |
Rilapladib
SB 659032 |
Phospholipase | Metabolism |
Rilapladib (SB 659032) 是 Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) 的选择性抑制剂 (IC50 = 230 pM) 和血小板活化因子受体的拮抗剂。 | |||
T13600 |
CDD3505
4-nitro-1-trityl-1H-imidazole |
P450 | Metabolism |
CDD3505 (4-nitro-1-trityl-1H-imidazole) 能够诱导肝CYP3A 的活动,增强高密度脂蛋白胆固醇的水平。 | |||
T31204 |
Darapladib-impurity
|
Others | Others |
Darapladib-impurity 是 Darapladib 的杂质。Darapladib 对脂蛋白相关磷脂酶 A2 (Lp-PLA2)有抑制作用。 | |||
T20887 |
Atorvastatin Sodium
Lipitor |
LDL; Aquaporin; HMG-CoA Reductase | Membrane transporter/Ion channel; Metabolism |
Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂,增加肝细胞上低密度脂蛋白(LDL)受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。 | |||
T77695 |
Muvalaplin
LY3473329 |
Others | Others |
Muvalaplin (LY3473329) 是一种具有口服活性的脂蛋白 (a) Lp (a) 抑制剂,可阻断 apo(a)-apo B100 相互作用来抑制 Lp(a) 的形成。 | |||
T41160 |
Lalistat 2
|
Lipase | Metabolism |
Lalistat 2 是一种溶酶体酸性脂肪酶的特异性抑制剂,IC50 为 152 nM,对人胰脂肪酶或牛乳脂蛋白脂肪酶没有抑制作用(高达 10 μM)。 | |||
T6267 |
Lomitapide
AEGR-733,洛美他派,BMS-201038 |
CETP | Metabolism |
Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂,体内试验的IC50值为8 nM。 | |||
T76739 |
Bococizumab
RN316,PF-04950615 |
Others | Others |
Bococizumab(PF-04950615) 是一种针对PCSK9的人源化mAb,也是一种在肝脏中合成PCSK9的抑制剂,可降低低密度脂蛋白胆固醇 (LDL-C) 在血液中的含量。Bococizumab 可用于治疗高胆固醇血症。 | |||
T72025 |
PCSK9-IN-10
|
Serine/threonin kinase | Cell Cycle/Checkpoint; Metabolism |
PCSK9-IN-10 是一种有效的,具有口服活性的PCSK9抑制剂,IC50值为 6.4 µM。PCSK9-IN-10 增加LDLR 蛋白的表达并降低 PCSK9 的表达。PCSK9-IN-10 可减缓动脉粥样硬化进展。PCSK9-IN-10 具有研究高脂血症的潜力。 | |||
T15020 |
CU-CPT22
|
TLR | Immunology/Inflammation |
CU-CPT22 是 toll 样受体 1 和 2 蛋白复合物抑制剂,可阻断 Pam3CSK4诱导的 TLR1/2 激活,IC50值为 0.58 µM。 它与 TLR1/2 结合的合成三酰脂蛋白竞争,Ki 值为 0.41 µM。 | |||
T2534 |
Pitavastatin calcium
P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104 |
Apoptosis; Mitophagy; Endogenous Metabolite; HMG-CoA Reductase; Autophagy | Apoptosis; Autophagy; Metabolism |
Pitavastatin calcium (NK-104) 是一种羟甲基戊二酰-CoA 还原酶抑制剂。它在 HepG2 细胞中抑制乙酸合成胆固醇的IC50为 5.8 nM。它是高效的肝细胞低密度脂蛋白胆固醇受体诱导剂。具有抗癌活性。 | |||
T26644 |
Apomine
SK&F-99085,APB-231-A2,APB-231-A-2,SR-9223i,SK&F-99085,SR-45023A |
HMG-CoA Reductase | Metabolism |
Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂,可在体外促进骨髓瘤细胞的凋亡,并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。 | |||
T7072 |
Pitavastatin
|
Others | Others |
Pitavastatin (NK-104) 是有效的羟甲基戊二酰-CoA(HMG-CoA)还原酶抑制剂。Pitavastatin 抑制乙酸合成胆固醇,在 HepG2 细胞中的IC50为 5.8 nM。Pitavastatin 是一种高效的肝细胞低密度脂蛋白胆固醇 (LDL-C) 受体诱导剂。Pitavastatin 具有抗动脉粥样硬化、抗哮喘、抗骨关节炎、抗肿瘤、神经保护、肝保护和肾保护等作用。 | |||
T22816 |
GSK 264220A
|
Others | Others |
endothelial lipase and lipoprotein lipase inhibitor | |||
T32892 |
LR 16
LR16,LR-16 |
Others | Others |
LR 16 has potent effects on oxygen affinity of hemoglobin, on blood cholesterol and on low density lipoprotein. | |||
T34954 |
Tripalmitoyl cysteine
Tripalmitoyl-S-glyceryl cysteine |
Others | Others |
Tripalmitoyl cysteine is a synthetic analog of the N-terminal lipid part of bacterial lipoprotein. | |||
T11386 |
Gemcabene calcium
PD-72953 calcium |
Others | Others |
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP). | |||
T75158 |
Olpasiran
|
Others | Others |
Olpasiran 是一种siRNA,可减少肝脏中脂蛋白 lipoprotein(a) 的合成。 | |||
T70504 |
6,8-Diprenyleriodictyol
|
Others | Others |
6,8-Diprenyleriodictyol is an antioxidant, which inhibits Cu(2+)-mediated oxidation of human low density lipoprotein (LDL). | |||
T32782 |
Lipopeptin A
|
Others | Others |
Lipopeptin A is a lipoprotein subclass that is a risk factor for atherosclerotic diseases such as coronary heart disease and stroke. | |||
TP2399 |
Palmitoyl tetrapeptide
Pam-ser-ser-asn-ala |
||
Palmitoyl tetrapeptide is an analog of the N-terminal part of lipoprotein from the outer membrane of E. coli. | |||
T70320 |
GNLPT-IN-1
|
Others | Others |
GNLPT-IN-1 is an inhibitor of gram-negative lipoprotein trafficking. | |||
T11873 |
Lp-PLA2-IN-2
|
Phospholipase | Metabolism |
Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2. | |||
T70624 |
S 12340
|
Others | Others |
S 12340 is a potent inhibitor of the oxidative modification of low-density lipoprotein. | |||
T22405 |
Pravastatin
|
Others | Others |
Pravastatin is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins. | |||
T33660 |
Nicofibrate hydrochloride
Nicofibrate HCl,Arterium V,Nicofibrate hydrochloride, |
Others | Others |
Nicofibrate hydrochloride is a biochemical which may cause a significant reduction in plasma cholesterol and triglycerides and bring lipoprotein levels to normal. Nicofibrate HCl may also lead to a significant drop in plasma prothrombinic activity. | |||
T2968L |
Hyodeoxycholic acid sodium salt
Sodium hyodeoxycholate,HDCA sodium |
Others | Others |
Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein function, reduces farnesoid X receptor antagonist bile acids, and induces strong cytotoxicity, apoptosis, and IL-8 synthesis. | |||
T15004 |
CP-532623
|
CETP | Metabolism |
CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol. | |||
TP2336 |
Tripalmitoyl pentapeptide
P3C-Ssna,Bpppcssaa,Bppp cssaa,Bppp-cssaa,P3C Ssna P3CSsna |
||
Tripalmitoyl pentapeptide is a Mitogen from E Coli lipoprotein. It also is a potent macrophage B lymphocyte activator. | |||
T38908 |
MK-8262
|
Others | Others |
MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (HDL) and low-density lipoprotein (LDL) with potential implications for coronary heart disease (CHD). | |||
T68504 |
Obicetrapib calcium
|
Others | Others |
Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. | |||
T28196 |
NS-220
LS-191458,NS 220 |
Others | Others |
NS-220, a selective agonist of peroxisome proliferator-activated receptor alpha, potently decreases plasma triglyceride and glucose levels and modifies lipoprotein profiles in KK-Ay mice. | |||
T79076 |
Lp-PLA2-IN-16
|
Phospholipase | Metabolism |
Lp-PLA2-IN-16 (example 1) 为Lp-PLA2 (脂蛋白相关磷脂酶A2) 的一种抑制剂,主要在阿尔茨海默病等相关研究中应用。 | |||
T79075 |
Lp-PLA2-IN-15
|
Phospholipase | Metabolism |
Lp-PLA2-IN-15 (example 2) 为一脂蛋白相关磷脂酶 A2 (Lp-PLA 2) 抑制剂,适用于阿尔茨海默病研究。 | |||
T15709 |
Lapaquistat acetate
TAK-475 |
Others | Others |
Lapaquistat acetate is a squalene synthase inhibitor. It also blocks the conversion of farnesyl diphosphate (FPP) to squalene. Lapaquistat acetate is used to Mevalonate Kinase Deficiency (MKD), it is effective at lowering low-density lipoprotein cholester | |||
T11343 |
G0507
|
Others | Others |
G0507 is a pyrrolopyrimidinedione compound that serves as a potent inhibitor of Escherichia coli growth, effectively inducing the extracytoplasmic σE stress response. It acts as a valuable chemical probe, specifically designed to dissect lipoprotein trafficking in Gram-negative bacteria. Notably, G0507 demonstrates strong inhibitory activity against the LolCDE ABC Transporter. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S0246 |
Pseudoprotodioscin
山药 |
Others; Fatty Acid Synthase | Metabolism; Others |
Pseudoprotodioscin 是一种呋喃葡糖苷,抑制SREBP1/2和microRNA 33a/b 水平,降低胆固醇和甘油三酯合成相关的基因表达。 | |||
T10017 |
1-Linoleoyl Glycerol
Glycerol 1-monolinolate,Monolinolein,一亚油酸甘油酯,Glyceryl monolinoleate,1-Linoleoyl-rac-glycerol |
Phospholipase | Metabolism |
1-Linoleoyl Glycerol (Monolinolein) 是脂肪酸甘油。 | |||
T4889 |
2,6-Diaminoheptanedioic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。 | |||
T5242 |
Triarachidin
Triarachin,1,2,3-Trieicosanoyl Glycerol,Glycerol Trieicosanoate,三花生精 |
Others; Endogenous Metabolite | Metabolism; Others |
Triarachidin (1,2,3-Trieicosanoyl Glycerol) 是内源性代谢产物的一种。 | |||
T5280 |
3-Chloro-L-Tyrosine
3-氯-L-酪氨酸,3-Chlorotyrosine,Chlorotyrosine |
Others; Endogenous Metabolite | Metabolism; Others |
3-Chloro-L-Tyrosine (Chlorotyrosine) 是一种髓过氧化物酶催化氧化的特异性标志物,在从人动脉粥样硬化内膜分离的低密度脂蛋白中显著升高。 | |||
TN5057 |
Stachybotramide
|
LDL | Metabolism |
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) and low density lipoprotein (LDL). | |||
T77289 |
5-O-Methylembelin
|
Others | Others |
5-O-Methylembelin 是一种天然异香豆素,可抑制PCSK9、低密度脂蛋白受体 (IDOL) 和甾醇调节元件结合蛋白 2 (SREBP2) mRNA 的表达。 | |||
TN5174 |
Trichosanatine
|
MMP; LDL; p38 MAPK; Lipoxygenase; ROS | Immunology/Inflammation; MAPK; Metabolism; Proteases/Proteasome |
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine can alleviate oxidized low-density lipoprotein induced endothelial cells injury via inhibiting the LOX-1/p38 MAPK pathway. | |||
T36563 |
(E)-Guggulsterone
|
Others | Others |
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01014 |
LDLR Protein, Mouse, Recombinant (His)
low density lipoprotein receptor,Hlb301 |
Mouse | HEK293 Cells |
LDLR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.7 kDa and the accession number is P35951. | |||
TMPY-01085 |
VLDLR Protein, Human, Recombinant (His)
VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein ... |
Human | HEK293 Cells |
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ... | |||
TMPY-00989 |
LDLR Protein, Human, Recombinant (His)
low density lipoprotein receptor,FHC,FH,LDLCQ2,LDL ... |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is A0A024R7D5. | |||
TMPY-01030 |
TFPI Protein, Human, Recombinant (His)
TFPI1,tissue factor pathway inhibitor (lipoprotein-... |
Human | HEK293 Cells |
TFPI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1. | |||
TMPY-06409 |
LPL Protein, Chinese hamster, Recombinant (His)
lipoprotein lipase |
Chinese hamster | E. coli |
LPL Protein, Chinese hamster, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 51.35 kDa and the accession number is G3H6V7-1. | |||
TMPH-00651 |
Lpp Protein, E. coli, Recombinant (His & KSI)
Major outer membrane lipoprotein Lpp,Braun lipo... |
E. coli | E. coli |
An outer membrane lipoprotein that controls the distance between the inner and outer membranes; adding residues to Lpp increases the width of the periplasm. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to the maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. The m... | |||
TMPH-00703 |
Pal Protein, E. coli, Recombinant (His & Myc)
Peptidoglycan-associated lipoprotein,pal,Tol-Pal sy... |
E. coli | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. The Tol-Pal system is also required for polar localization of chemoreceptors clusters. The system also appears to be required for the activity of several outer membrane-localized enzymes with cell wall remodeling activity. | |||
TMPY-05348 |
LDLR Protein, Mouse, Recombinant (His), Biotinylated
Hlb301,low density lipoprotein receptor |
Mouse | HEK293 Cells |
LDLR Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.7 kDa and the accession number is P35951. | |||
TMPH-00650 |
LptE Protein, E. coli, Recombinant (His & Myc)
LPS-assembly lipoprotein LptE,lptE |
E. coli | E. coli |
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | |||
TMPH-02762 |
LPL Protein, Mouse, Recombinant
Phospholipase A1,Lipoprotein lipase,Lpl |
Mouse | E. coli |
LPL Protein, Mouse, Recombinant is expressed in E. coli. | |||
TMPJ-00394 |
LDLR Protein, Human, Recombinant (Avi & His), Biotinylated
Low-Density Lipoprotein Receptor,LDL Receptor,LDLR |
Human | HEK293 Cells |
Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repeats. This protein binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, it functions as a r... | |||
TMPH-02760 |
LPL Protein, Mouse, Recombinant (His & Myc)
Phospholipase A1,Lpl,Lipoprotein lipase |
Mouse | E. coli |
LPL Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 57.3 kDa and the accession number is P11152. | |||
TMPH-02761 |
LPL Protein, Mouse, Recombinant (His)
Phospholipase A1,Lipoprotein lipase,Lpl |
Mouse | Baculovirus Insect Cells |
LPL Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 52.8 kDa and the accession number is P11152. | |||
TMPH-03172 |
OprI Protein, Pseudomonas aeruginosa, Recombinant (His)
Major outer membrane lipoprotein,oprI |
Pseudomonas aeruginosa | E. coli |
OprI Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 12.9 kDa and the accession number is P11221. | |||
TMPH-00694 |
LolA Protein, E. coli O9:H4, Recombinant (His)
Outer-membrane lipoprotein carrier protein,lolA |
E. coli | P. pastoris (Yeast) |
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | |||
TMPH-02409 |
LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
27 kDa lipoprotein,lprG,Triacylglyceride transfer p... |
Mycobacterium tuberculosis | E. coli |
LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.2 kDa and the accession number is P9WK44. | |||
TMPH-00552 |
Lpp Protein, Erwinia amylovora, Recombinant (His & SUMO)
Major outer membrane lipoprotein Lpp,lpp |
Erwinia amylovora | E. coli |
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. | |||
TMPH-01612 |
LSR Protein, Human, Recombinant (His)
Lipolysis-stimulated lipoprotein receptor,Angulin-1... |
Human | E. coli |
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. | |||
TMPH-02399 |
Pal Protein, Legionella pneumophila, Recombinant (E. coli, His)
pal,19 kDa surface antigen,Peptidoglycan-associated lipo... |
Legionella pneumophila | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan. | |||
TMPY-03975 |
LRP-11 Protein, Human, Recombinant (His)
MANSC3,bA350J20.3,low density lipoprotein receptor-... |
Human | HEK293 Cells |
LRP-11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is Q86VZ4-1. | |||
TMPH-00716 |
RzoR Protein, E. coli, Recombinant (Flag & His)
Prophage outer membrane lipoprotein RzoR,Spanin fro... |
E. coli | E. coli |
Component of the spanin complex that disrupts the outer membrane and causes cell lysis during virus exit. The spanin complex conducts the final step in cell lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans. | |||
TMPH-02400 |
Pal Protein, Legionella pneumophila, Recombinant (His)
19 kDa surface antigen,Peptidoglycan-associated lipoprot... |
Legionella pneumophila | P. pastoris (Yeast) |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan. | |||
TMPY-03351 |
LOX-1 Protein, Cynomolgus, Recombinant (His)
oxidized low density lipoprotein (lectin-like) rece... |
Cynomolgus | HEK293 Cells |
LOX-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.9 kDa and the accession number is G7PJT2. | |||
TMPY-05809 |
LDLR Protein, Human, Recombinant (193D/A, His)
low density lipoprotein receptor,LDL R,LDL Receptor... |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (193D/A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.19 kDa and the accession number is A0A024R7D5. | |||
TMPY-05323 |
LDLR Protein, Human, Recombinant (mFc)
LDL R,FH,LDLCQ2,LDL Receptor,low density lipoprotein |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 111.2 kDa and the accession number is A0A024R7D5. | |||
TMPH-03086 |
Pal Protein, Pasteurella multocida, Recombinant (His & SUMO)
Peptidoglycan-associated lipoprotein,pal,Outer memb... |
Pasteurella multocida | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Pal Protein, Pasteurella multocida, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is Q51886. | |||
TMPY-00383 |
LDLRAD3 Protein, Human, Recombinant (hFc)
LRAD3,low density lipoprotein receptor class A doma... |
Human | HEK293 Cells |
LDLRAD3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is Q86YD5-1. | |||
TMPY-00557 |
GPIHBP1 Protein, Human, Recombinant (hFc)
glycosylphosphatidylinositol anchored high density lipop... |
Human | HEK293 Cells |
GPIHBP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q8IV16. | |||
TMPY-05499 |
LDLR Protein, Human, Recombinant (His), Biotinylated
LDL Receptor,LDL R,low density lipoprotein receptor... |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is A0A024R7D5. | |||
TMPY-00928 |
TFPI Protein, Mouse, Recombinant (His)
AW552122,A630013F22Rik,tissue factor pathway inhibitor (... |
Mouse | HEK293 Cells |
TFPI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is O54819-1. | |||
TMPY-00559 |
GPIHBP1 Protein, Human, Recombinant (His)
GPI-HBP1,HYPL1D,glycosylphosphatidylinositol anchored high d... |
Human | HEK293 Cells |
GPIHBP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is Q8IV16. | |||
TMPH-01616 |
LRP2 Protein, Human, Recombinant (mFc)
Glycoprotein 330,Megalin,Low-density lipoprotein re... |
Human | HEK293 Cells |
LRP2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50.8 kDa and the accession number is P98164. | |||
TMPY-04066 |
LOX-1 Protein, Rat, Recombinant (His)
oxidized low density lipoprotein (lectin-like) rece... |
Rat | HEK293 Cells |
LOX-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is O70156. | |||
TMPY-03371 |
LOX-1 Protein, Rat, Recombinant (hFc)
OLR1,Lox1,Oldlr1,oxidized low density lipoprotein (... |
Rat | HEK293 Cells |
LOX-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.9 kDa and the accession number is O70156. | |||
TMPY-05179 |
TFPI Protein, Human, Recombinant (His), Biotinylated
TFI,TFPI1,EPI,LACI,tissue factor pathway inhibitor (lipo... |
Human | HEK293 Cells |
TFPI Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1. | |||
TMPH-03590 |
PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc)
psaA,Manganese ABC transporter substrate-binding lipopro... |
Streptococcus pneumoniae | E. coli |
Part of an ATP-driven transport system. PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.0 kDa and the accession number is P0A4G3. | |||
TMPH-03211 |
TFPI Protein, Rabbit, Recombinant (His)
TFPI,Lipoprotein-associated coagulation inhibitor,E... |
Rabbit | HEK293 Cells |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is P19761. | |||
TMPY-02653 |
LRP-10 Protein, Human, Recombinant (hFc)
low density lipoprotein receptor-related protein 10... |
Human | HEK293 Cells |
LRP-10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73 kDa and the accession number is Q7Z4F1-1. | |||
TMPH-03591 |
PsaA Protein, S. pneumoniae, Recombinant (His & Myc)
Manganese ABC transporter substrate-binding lipoprotein<... |
Streptococcus pneumoniae | E. coli |
Part of an ABC transporter complex involved in manganese import. PsaA Protein, S. pneumoniae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.9 kDa and the accession number is P42363. | |||
TMPY-02748 |
LRP-10 Protein, Human, Recombinant (His)
MST087,LRP9,low density lipoprotein receptor-relate... |
Human | HEK293 Cells |
LRP-10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.5kDa and the accession number is Q7Z4F1-1. | |||
TMPH-03210 |
TFPI Protein, Rabbit, Recombinant (E. coli, His)
Lipoprotein-associated coagulation inhibitor,Extrin... |
Rabbit | E. coli |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761. | |||
TMPH-03589 |
PsaA Protein, S. oralis, Recombinant (His & Myc)
Manganese ABC transporter substrate-binding lipoprotein<... |
Streptococcus oralis | E. coli |
Part of an ATP-driven transport system. PsaA Protein, S. oralis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.1 kDa and the accession number is Q9L5W9. | |||
TMPH-00392 |
Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO)
omcA,Small cysteine-rich outer membrane protein OmcA,9 kDa c... |
Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is... | |||
TMPY-04124 |
LPAL2 Protein, Human, Recombinant (mFc)
APOARGC,APOAL,lipoprotein, Lp(a)-like 2, pseudogene... |
Human | HEK293 Cells |
LPAL2 (Lipoprotein(A) Like 2, Pseudogene) is a Pseudogene. This gene is similar to the lipoprotein, Lp(a) gene, but all transcripts produced by this gene contain a truncated open reading frame and are candidates for nonsense-mediated decay. Lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). Mutations in the solute carrier family 22 member 3 (SLC22A3), lipoprotein (a)-like 2 (LPAL2), and the lipoprotein ... | |||
TMPY-02490 |
LOX-1 Protein, Human, Recombinant (His)
LOXIN,SCARE1,SLOX1,LOX1,OLR1,oxidized low density lipopr... |
Human | HEK293 Cells |
LOX-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P78380. | |||
TMPJ-01412 |
LRP-12 Protein, Human, Recombinant (His)
LRP-12,ST7,Suppressor of Tumorigenicity 7 Protein,LRP12,Low-... |
Human | HEK293 Cells |
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as ... | |||
TMPY-01732 |
LRPAP1 Protein, Mouse, Recombinant (His)
C77774,AU042172,RAP,AI790446,low density lipoprotein |
Mouse | HEK293 Cells |
LRPAP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.4 kDa and the accession number is P55302. | |||
TMPH-02502 |
LRPAP1 Protein, Mouse, Recombinant (His & Myc)
Heparin-binding protein 44,Alpha-2-macroglobulin receptor-as... |
Mouse | Baculovirus Insect Cells |
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. LRPAP1 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is P55302. | |||
TMPY-01233 |
LRPAP1 Protein, Human, Recombinant (His)
HBP44,MYP23,low density lipoprotein receptor-relate... |
Human | HEK293 Cells |
LRPAP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is P30533. | |||
TMPY-02956 |
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
APOL1,apolipoprotein L1,APOL,FSGS4,APOL-I,APO-L |
Human | Baculovirus Insect Cells |
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0119 |
Pitavastatin-d4 Sodium Salt
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Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。 |