|
TMPH-01985
|
ASAH2B Protein, Human, Recombinant (His)
ASAH2L,ASAH2B,Putative inactive non-lysosomal ceram...
|
Human
|
E. coli
|
|
N/A. ASAH2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C7U1. |
|
TMPH-00492
|
PNLIPRP1 Protein, Canine, Recombinant (His & SUMO)
Inactive pancreatic lipase-related protein 1,PNLIPR...
|
Canine
|
E. coli
|
|
May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro). PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.7 kDa and the accession number is P06857. |
|
TMPH-00491
|
PNLIPRP1 Protein, Canine, Recombinant (His)
Inactive pancreatic lipase-related protein 1,PNLIPR...
|
Canine
|
P. pastoris (Yeast)
|
|
May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro). PNLIPRP1 Protein, Canine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.7 kDa and the accession number is P06857. |
|
TMPH-01733
|
DDAH2 Protein, Human, Recombinant (GST & His)
Inactive dimethylarginine dimethylaminohydrolase 2,...
|
Human
|
E. coli
|
|
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 61.2 kDa and the accession number is O95865. |
|
TMPH-01527
|
NAALADL2 Protein, Human, Recombinant (His)
Inactive N-acetylated-alpha-linked acidic dipeptida...
|
Human
|
E. coli
|
|
May be catalytically inactive. |
|
TMPH-01526
|
KMT2E Protein, Human, Recombinant (His & Myc)
Inactive histone-lysine N-methyltransferase 2E,Myel...
|
Human
|
E. coli
|
|
Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Also acts as an important cell cycle regulator, participating in cell cycle r... |
|
TMPH-02738
|
IRAK3 Protein, Mouse, Recombinant (His & Myc)
Irak3,Inactive IL-1 receptor-associated kinase 3,IL...
|
Mouse
|
Baculovirus Insect Cells
|
|
Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells. IRAK3 Protein, Mouse, Recombinant (His & Myc) is expressed in ... |
|
TMPH-02739
|
IRAK3 Protein, Mouse, Recombinant (E. coli, His & Myc)
IL-1 receptor-associated kinase M,Inactive IL-1 rec...
|
Mouse
|
E. coli
|
|
IRAK3 Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli. |
|
TMPH-01525
|
CMAHP Protein, Human, Recombinant (His & Myc)
CMAHP,Inactive cytidine monophosphate-N-acetylneura...
|
Human
|
E. coli
|
|
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates. However, it may play a role in Wnt signaling. |
|
TMPH-01226
|
CRMP1 Protein, Human, Recombinant
ULIP3,Collapsin response mediator protein 1,CRMP1,Dihydropyr...
|
Human
|
E. coli
|
|
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis. CRMP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted mole... |
|
TMPJ-00258
|
TGF beta 2 Protein, Human, Recombinant
Glioblastoma-derived T-cell suppressor factor,TGF-β-2,Transf...
|
Human
|
HEK293 Cells
|
|
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be... |
|
TMPY-02115
|
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
CRISTIN1,THSD2,R-spondin 3,PWTSR
|
Human
|
HEK293 Cells
|
|
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s... |
|
TMPY-02078
|
HtrA2/Omi Protein, Human, Recombinant (His)
PARK13,OMI,HtrA serine peptidase 2,PRSS25
|
Human
|
E. coli
|
|
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the peptidase S1B family. HTRA2 contains one PDZ (DHR) domain. HTRA2 is a serine protease that shows proteolytic activity against a non-specific substrate beta-casein. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor... |
|
TMPJ-00375
|
HGF Protein, Human, Recombinant (His)
Scatter factor,Hepatocyte growth factor,HGF,SF,Hepatopoietin...
|
Human
|
HEK293 Cells
|
|
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia... |
|
TMPH-00655
|
McjB Protein, E. coli, Recombinant (His & Myc)
Microcin J25-processing protein McjB,mcjB
|
E. coli
|
E. coli
|
|
Along with McjC, necessary and sufficient to process the inactive microcin J25 (McjA) precursor into the active peptide. |
|
TMPH-00293
|
PAG-1 Protein, Bovine, Recombinant (His)
Pregnancy-specific protein B,Pregnancy-associated glycoprote...
|
Bovine
|
E. coli
|
|
Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.7 kDa and the accession number is Q29432. |
|
TMPH-00294
|
PAG-1 Protein, Bovine, Recombinant (His & SUMOstar)
Pregnancy-associated glycoprotein 1,Pregnancy-specific prote...
|
Bovine
|
P. pastoris (Yeast)
|
|
Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 49.8 kDa and the accession number is Q29432. |
|
TMPH-01736
|
PGLYRP2 Protein, Human, Recombinant (His)
PGLYRP2,Peptidoglycan recognition protein long,Peptidoglycan...
|
Human
|
P. pastoris (Yeast)
|
|
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 62.0 kDa and the accession number is Q96PD5. |
|
TMPH-00844
|
HSD11B2 Protein, Human, Recombinant (His)
HSD11B2,11-beta-hydroxysteroid dehydrogenase type 2,Short ch...
|
Human
|
P. pastoris (Yeast)
|
|
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365. |
|
TMPH-01737
|
PGLYRP2 Protein, Human, Recombinant (His & SUMO)
N-acetylmuramoyl-L-alanine amidase,Peptidoglycan recognition...
|
Human
|
E. coli
|
|
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 76.0 kDa and the accession number is Q96PD5. |
|
TMPJ-00553
|
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
PAF Acetylhydrolase,LDL-Associated Phospholipase A2,LDL-PLA(...
|
Human
|
HEK293 Cells
|
|
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen... |
|
TMPJ-01116
|
HABP2 Protein, Human, Recombinant (His)
Factor seven-activating protease,Factor VII-activating prote...
|
Human
|
HEK293 Cells
|
|
Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate... |
|
TMPH-00134
|
AcMNPV Viral cathepsin Protein (His & SUMO)
Cysteine proteinase,Viral cathepsin,VCATH,V-cath
|
AcMNPV
|
E. coli
|
|
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteolytic cleavage upon cell death. AcMNPV Viral cathepsin Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.9 kDa and the accession number is P25783. |
|
TMPJ-00881
|
CTRB1 Protein, Human, Recombinant (His)
CTRB,CTRB1,Chymotrypsinogen B
|
Human
|
HEK293 Cells
|
|
Chymotrypsinogen B (CTRB1) is a 263 amino acid protein with signal peptide (1-18) and Chymotrypsinogen B (19-263). Chymotrypsinogen B have three chains:Chymotrypsin B chain A(19-31), Chymotrypsin B chain B(34-164), Chymotrypsin B chain C (167-263). Chymotrypsinogen B is a Serine Protease Hydrolase secrets into gastrointestinal tract as the inactive precursor Chymotrypsinogen. |
|
TMPH-00507
|
PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)
PGRP-SC2,Peptidoglycan-recognition protein SC2
|
Fruit fly
|
E. coli
|
|
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no direct bacteriolytic activity. PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9V4X2. |
|
TMPH-00843
|
HSD11B1 Protein, Human, Recombinant (His & SUMO)
7-oxosteroid reductase,11-beta-hydroxysteroid dehydrogenase ...
|
Human
|
E. coli
|
|
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol. HSD11B1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.5 kDa and the accession number is P28845. |
|
TMPJ-01393
|
Carboxypeptidase Q Protein, Mouse, Recombinant (His)
Plasma glutamate carboxypeptidase,Hls2,Hematopoietic lineage...
|
Mouse
|
HEK293 Cells
|
|
Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides with unsubstituted terminals into amino acids. Carboxypeptidase may play an important role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. The monomeric form is inactive while the homodimer is active. |
|
TMPY-00821
|
HGFA Protein (pro form), Human, Recombinant (His)
MGC138397,HGFA,RP11-529E1.2,肝细胞生长因子,MGC138395
|
Human
|
HEK293 Cells
|
|
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is clea... |
|
TMPY-02544
|
FANCA Protein, Human, Recombinant (His)
FA-H,FA1,FAA,FAH,FANCH,FACA,Fanconi anemia, complementation ...
|
Human
|
Baculovirus Insect Cells
|
|
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2. |
|
TMPH-01041
|
Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)
CPAH,CPA6,Carboxypeptidase A6
|
Human
|
E. coli
|
|
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine. Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular w... |
|
TMPJ-01229
|
SUMF1 Protein, Human, Recombinant (His)
C-Alpha-Formylglycine-Generating Enzyme 1,FGE,C-α-Formylglyc...
|
Human
|
HEK293 Cells
|
|
Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known. |
|
TMPH-01209
|
DENND1A Protein, Human, Recombinant (His & SUMO)
KIAA1608,Connecdenn 1,DENN domain-containing protein 1A,DENN...
|
Human
|
E. coli
|
|
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes. Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P. DENND1A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6... |
|
TMPH-01508
|
HABP2 Protein, Human, Recombinant (His & SUMO)
Hepatocyte growth factor activator-like protein,Factor VII-a...
|
Human
|
E. coli
|
|
Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulat... |
|
TMPJ-00897
|
TPSB2 Protein, Mouse, Recombinant (His)
Tryptase-2,Mast cell protease 6,Tryptase beta-2,Tryptase β-2...
|
Mouse
|
HEK293 Cells
|
|
Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It plays a role in innate immunity. Tpsb2 can be detected primarily in skin during embryogenesis. Tpsb2 can not be detected at early embryonic stages but is abundantly expressed in later stages with a peak at E17.5-E18.5. Tryp... |
|
TMPH-02020
|
RGS17 Protein, Human, Recombinant (GST)
Regulator of G-protein signaling 17,RGS17
|
Human
|
E. coli
|
|
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins. R... |
|
TMPH-02334
|
RAB12 Protein, Human, Recombinant (His & Myc)
Ras-related protein Rab-12,RAB12
|
Human
|
E. coli
|
|
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degrada... |
|
TMPJ-00250
|
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
transforming growth factor β1,TGFβ,CED,TGFB,TGFbeta,LAP (TGF...
|
Human
|
HEK293 Cells
|
|
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ... |
|
TMPJ-01001
|
CCL11 Protein, Human, Recombinant
SCYA11,C-C Motif Chemokine 11,Eosinophil Chemotactic Protein...
|
Human
|
E. coli
|
|
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its recept... |
|
TMPH-01388
|
GCKR Protein, Human, Recombinant (His & SUMO)
GCKR,Glucokinase regulatory protein
|
Human
|
E. coli
|
|
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. GCKR Protein, Human, R... |
|
TMPH-01387
|
GCKR Protein, Human, Recombinant (His)
Glucokinase regulatory protein,GCKR
|
Human
|
P. pastoris (Yeast)
|
|
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. GCKR Protein, Human, R... |
|
TMPJ-00815
|
FBPase1 Protein, Human, Recombinant (His, E. coli)
6-Bisphosphate 1-Phosphohydrolase 1,FBP1,FBP,FBPase 1,D-Fruc...
|
Human
|
E. coli
|
|
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young chi... |
|
TMPJ-00962
|
AKR1C3 Protein, Human, Recombinant (His)
3-Alpha-HSD Type 2,17-β-Hydroxysteroid Dehydrogenase Type 5,...
|
Human
|
HEK293 Cells
|
|
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and ... |
|
TMPJ-01225
|
PDILT Protein, Human, Recombinant (His)
PDILT,Protein Disulfide-Isomerase-Like Protein of the Testis
|
Human
|
HEK293 Cells
|
|
Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid signal sequence and a 564 amino acid mature chain. PDILT contains 1 thioredoxin domain lacks the conserved redox-active Cys at position 417 which is replaced by a Ser residue, suggesting that it lacks thioredoxin activity. PDILT is an enzyme in the endoplasmic reticulum in eukary... |
|
TMPY-01580
|
PRSS2 Protein, Mouse, Recombinant (His)
Tesp4,protease, serine 2,Try2,Ta,TRY8,TRYP,Prss2
|
Mouse
|
HEK293 Cells
|
|
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary ... |
|
TMPJ-00474
|
CPA1 Protein, Human, Recombinant (His)
CPA,Carboxypeptidase A1,CPA1
|
Human
|
HEK293 Cells
|
|
Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of hu... |
|
TMPJ-01292
|
Chemerin/RARRES2 Protein, Human, Recombinant (His)
RAR-responsive protein TIG2,RARRES2,Chemerin,Tazarotene-indu...
|
Human
|
HEK293 Cells
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Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thou... |
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TMPY-03747
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Fucose Mutarotase Protein, Human, Recombinant (His)
fucose mutarotase,FucM,C10orf125,FUCU
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Human
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E. coli
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FUOM, also known as fucose mutarotase and FucM, belongs to the RbsD / FucU family. FUOM is involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose has two isforms: alpha-L-fucose (29.5%) and beta-L-fucose (7.5%). The beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated struc... |
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TMPY-02965
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MMP-19 Protein, Human, Recombinant
MMP18,matrix metallopeptidase 19,RASI-1
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Human
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E. coli
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MMP19, also known as RASI-1, is a member of the peptidase M1A family. It contains 4 hemopexin-like domains and is expressed in the mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart, and blood vessel walls. It is a matrix metalloproteinase (MMP). Proteins of the MMP family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well a... |
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TMPJ-00869
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GLB1 Protein, Human, Recombinant (His)
Lactase,Acid Beta-Galactosidase,Elastin Receptor 1,GLB1,Acid...
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Human
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HEK293 Cells
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β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-ga... |
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TMPY-03608
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EEF1B2 Protein, Human, Recombinant (His)
EEF1B,eukaryotic translation elongation factor 1 beta 2,EEF1...
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Human
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E. coli
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EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, they facilitate translational elongation, from the formation of the first peptide bond to the formation of the last one. EF1B is more complex in eukaryotes than in bacteria, and consists of three subunits: EF1B-alpha, EF1B-gamma and EF1B-beta. EF1B contains 1 GST C-terminal domain. ... |
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