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N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine).
N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | ¥ 2,880 | 35日内发货 | |
50 μg | ¥ 5,470 | 35日内发货 | |
100 μg | ¥ 9,870 | 35日内发货 |
产品描述 | N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine). |
别名 | N-acetyl Leukotriene E4 |
分子量 | 481.65 |
分子式 | C25H39NO6S |
CAS No. | 80115-95-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | DMF: >50 mg/mL (per Ramki Iyer) Ethanol: >50 mg/mL (per Ramki Iyer) DMSO: >50 mg/mL (per Ramki Iyer) PBS (pH 7.2): >100 μg/mL (per Ramki Iyer) |
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