70
4
67
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19033 |
Nile Red
Phenoxazone 9,尼罗红,Nile Blue A oxazone |
Others | Others |
Nile Red (Nile Blue A oxazone) 是一种选择性疏水性荧光染料,针对细胞内脂质小滴和中性脂质。它在所有有机溶剂中均具有强烈的荧光性,其荧光颜色范围从金黄色到深红色。 | |||
T3146 |
BMS-202
PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2 |
Apoptosis; PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
BMS-202 (PD1-PDL1 inhibitor 2) 是一种非肽类 PD-1/PD-L 复合物抑制剂,其 IC50为 18 nM,KD 为 8 μM。它与 PD-L1 直接结合并阻断人类 PD-1/PD-L 的相互作用,具有抗肿瘤活性。 | |||
T19507 |
Perfluamine
FTPA,Tris(perfluoropropyl)amine,Perfluorotripropylamine |
Others | Others |
Perfluamine (FTPA) 是一种疏水性载液,可用作血液替代品。 | |||
T19068 |
TMA-DPH
|
Others | Others |
TMA-DPH 是疏水性荧光膜探针 (Ex=355 nm; Em=430 nm)。 | |||
T19937 |
Pyronine B
NSC44690,NSC-44690,NSC 44690 |
Autophagy | Autophagy |
Pyronine B (NSC 44690) 是一种相对荧光团亮度较低的荧光团,也是小型疏水性 (SH) 蛋白通道抑制剂,可用于细菌和霉菌的染色,参与分光光度法测定超痕量钌。 | |||
T66152 |
NDSB-211
|
Others | Others |
NDSB-211 是一种具有较小的疏水端并能温和地溶解蛋白质的表面活性剂,可用于蛋白提取和分析。 | |||
T4072 |
Methyl-β-cyclodextrin
Methyl-beta-cyclodextrin,甲基-β-环糊精,甲基倍他环糊精,beta-Cyclodextrin methyl ethers |
Others | Others |
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) 是一种大环化合物,可以作为疏水性化合物的增溶剂用于生物实验中。Methyl-β-cyclodextrin 也是一种脂筏抑制剂,具有降胆固醇活性,还具有潜在抗肿瘤活性。 | |||
T72075 |
HyT36
|
Others | Others |
HyT36 是一种小分子疏水标签,可选择性的破坏稳定,促进融合蛋白和假激酶 Her3 的降解。HyT36可治疗表达 erht 的细胞诱导急性。 | |||
T37482 |
Diclofenac methyl ester
|
Others | Others |
Diclofenac methyl ester 是双氯芬酸(diclofenac)的疏水性前药形式,它是一种非甾体抗炎药 (NSAID)。它比双氯芬酸更易溶于肉豆蔻酸异丙酯,但毒性更高。 | |||
T4949 |
1,2-Didecanoyl-sn-glycero-3-phosphocholi
1,2-Didecanoyl Phosphatidylcholine,1,2-Didecanoyl PC,L-A-癸酰磷脂酰胆碱 |
Others | Others |
1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) 是一种合成的、疏水性较低的磷脂,已被发现可用于增强肽类药物和激素(如胰岛素)的吸收。 | |||
T8873 |
Bractoppin
|
Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Bractoppin 是一种BRCA1 (t)BRCT domain 识别磷酸肽的选择性抑制剂,IC50为 74 nM。它优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。它减少 BRCA1 对 DNA 断裂片段的招募,进而抑制损伤诱导的 G2 期阻滞和重组酶 RAD51 的组装。 | |||
T8782 |
MitoBloCK-11 (MB-11)
|
Others | Others |
MitoBloCK-11 (MB-11) 是线粒体蛋白输入的小分子抑制剂,可能通过转运蛋白 Seo1 起作用,但不通过 Tom70 或 Tom20;抑制含有疏水片段的前体蛋白,以特定方式在缺乏尿嘧啶的培养基中促进生长,并影响斑马鱼的发育。 | |||
T12492 |
Pivagabine
CXB-722,匹伐加宾 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Pivagabine (CXB-722) 是疏水性 4-氨基丁酸的衍生物,具有神经调节活性。它可穿透大鼠的血脑屏障,拮抗足部休克对大鼠脑中 GABAA 受体功能和促肾上腺皮质激素释放因子 (CRF) 浓度的影响。 | |||
T9103 |
BVDV-IN-1
|
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
BVDV-IN-1 是一种牛病毒性腹泻病毒 (BVDV) 的非核苷抑制剂 (NNI),EC50 为 1.8 μM。它直接与 BVDV RdRp 的疏水口袋结合,对耐 NNI 氨基硫脲 (TSC) 的 BVDV 具有抗病毒活性。 | |||
T73499 |
NG-497
NG497 |
Lipase | Metabolism |
NG-497 是一种具有选择性的小分子人类的脂肪甘油三酯脂肪酶 (ATGL) 抑制剂,可以靶向人类 ATGL 的酶促活性 patatin 样结构域。NG-497在活性位点附近的疏水腔内结合ATGL。NG-497以剂量依赖性和可逆的方式消除人脂肪细胞中的脂肪分解。NG-497 可用于研究癌症。 | |||
T35841 |
5-Benzyloxygramine
|
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
5-Benzyloxygramine 是一种 N 蛋白、蛋白互作的原位稳定剂,具有抗病毒和稳定 N-NTD 蛋白的作用。它能够阻断多巴胺受体,可拮抗 5-HT 对大鼠子宫和兔耳的作用。 | |||
T12149 |
N-Me-L-Ala-maytansinol
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
N-Me-L-Ala-maytansinol used for making antibody-drug conjugate (ADC),is a hydrophobic, cell permeable payload. | |||
T21141 |
Decylene glycol
Decane-1,2-diol,AI3-16595,1,2-Decanediol |
Others | Others |
Decylene glycol is used as an antimicrobial agent in cosmetics. It also suppresses the fluidity of the hydrophobic and hydrophilic groups in the phospholipid membrane of liposomes. | |||
T27529 |
HC-3
HC 3 |
Others | Others |
HC-3 inhibits ChoK by binding at the conserved hydrophobic groove on the C-terminal lobe. | |||
T84394 |
12-doxyl Stearic Acid
12-DSA |
Others | Others |
12-Doxyl stearic acid, a derivative of stearic acid featuring a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, functions as a hydrophobic spin label. This compound is prevalently utilized in research to investigate the molecular characteristics of membranes and hydrophobic proteins. | |||
T34253 |
Rad 242
Rad242,Rad-242 |
Others | Others |
Rad 242 is a hydrophobic lidocaine derivative. | |||
T19730 |
12-Crown-4
12 C 4,12-Crown-4 ether,12C4,12-C-4 |
Others | Others |
12-Crown-4 disrupts Aβ40 fibrils. 12-Crown-4 can enter into the hydrophobic core region and form competitive, hydrophobic interactions with key hydrophobic residues. | |||
T39676 |
CM121
CM121 |
Others | Others |
CM121 is a reversible inhibitor of ALDH1A2 that acts specifically on the active site, exhibiting an IC50 of 0.54 μM and a Kd of 1.1 μM. It exerts its inhibitory effect through multiple hydrophobic interactions. | |||
T19055 |
RT-NH2
Real Thiol-NH2 |
Others | Others |
RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus. It is a RealThiol prototype without the carboxylic acid groups. | |||
TP2460 |
Lys-phe-phe-phe-ile-ile-trp-och3
|
||
Lys-phe-phe-phe-ile-ile-trp-och3 is a hydrophobic peptide which reacts with lipid vesicles. | |||
T31530 |
Disoxaril
BRN 3626820,WIN51711,WIN-51711,BRN-3626820,WIN 51711,WIN-51,711 |
Others | Others |
Disoxaril (BRN 3626820, WIN 51711) is an anti-picornavirus agent that inhibits enterovirus replication by binding to a hydrophobic bag within the VP1 coat protein, thereby stabilizing virions and preventing their uncoating. When used in combination with A | |||
T80630 |
H-Arg-OtBu dihydrochloride
|
Antibiotic | Microbiology/Virology |
H-Arg-OtBu (dihydrochloride) 是一膜靶向抗菌剂,依靠电静力与疏水作用相结合,针对负电荷细菌膜。本化合物适用于细菌感染病研究之用。 | |||
T81699 |
NBD-amine
|
||
NBD-amine是荧光性质变化的胺类化合物,其在水介质中的荧光较弱,而在有机溶剂、膜结构以及疏水条件下则显著增强。 | |||
T77266 |
C13-112-tri-tail
|
Others | Others |
C13-112-tri-tail 是一种阳离子类脂化合物,可用于配制脂质纳米颗粒。 | |||
T77269 |
C13-113-tetra-tail
|
Others | Others |
C13-113-tetra-tail 是一种阳离子类脂化合物,可用于配制脂质纳米颗粒。 | |||
TP1341 |
Polymyxin B nonapeptide
|
||
Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probab | |||
TD0083 |
DiIiodide1,1‘-Dioctadecyl-3,3,3’,3‘-tetramethylindocarbocyanine iodide]
DiI碘化物 |
||
DiI iodide1 is one of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures. The fluorescence of these environment-sensitive dyes is greatly enhanced when incorporated into membranes or bound to lipophilic biomolecules such as proteins although they are weakly fluorescent in water. | |||
T35887 |
MBD
|
Others | Others |
MBD, a novel fluorescent probe (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), is utilized to study the conformation of protein and nucleoprotein. Its application is extended to bacterial ribosomes, as well as bovine trypsinogen and trypsin. MBD exhibits significant fluorescence when it binds to the hydrophobic region of macromolecules [1][2]. | |||
T20937 |
Dodecenylsuccinic anhydride
2-十二烯基-丁二酸酐,Rikacid DDSA,Dodecenylsuccinic acid anhydride,DDSA |
Others | Others |
Dodecenylsuccinic anhydride (DDSA) 可与胶原水凝胶接枝,作为疏水性伤口敷料掺入辛伐他汀后,在治疗溃疡和预防伤口感染方面具有潜在应用。 | |||
TD0084 |
DiI triflate [1,1‘-Dioctadecyl-3,3,3’,3‘-tetramethylindocarbocyanine triflate]
|
||
DiI triflate is one of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures. The fluorescence of these environment-sensitive dyes is greatly enhanced when incorporated into membranes or bound to lipophilic biomolecules such as proteins although they are weakly fluorescent in water. | |||
T77268 |
C13-112-tetra-tail
|
Others | Others |
C13-112-tetra-tail 是一种阳离子类脂化合物,可用于配制脂质纳米颗粒。 | |||
T75878 |
Catestatin TFA
|
||
Catestatin TFA,一个含有21个氨基酸残基、阳离子性疏水性肽,作为内源性肽,调节心脏功能及血压。它通过烟碱型乙酰胆碱受体(nAChRs)以非竞争性方式抑制儿茶酚胺释放,功能为烟碱类拮抗剂。 | |||
T80118 |
α-Synuclein (61-95) (human)
|
||
α-Synuclein(61-95) (human) 是 α-Synuclein 的疏水核心区段,具有诱导神经元死亡的能力。该肽段在神经退行性疾病的研究中有应用,涉及阿尔茨海默病 (AD) 与帕金森病 (PD)。 | |||
T37147 |
5'-O-DMT-N4-Ac-dC
5'-O-DMT-N4-Ac-dC |
Others | Others |
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7) is a deoxynucleoside utilized in the synthesis of dodecyl phosphoramidite. Dodecyl phosphoramidite serves as a crucial precursor for dod-DNA production, which is amphiphilic DNA comprising dodecyl phosphotriester linkages and featuring an internal hydrophobic region[1][2]. | |||
T77267 |
C13-113-tri-tail
|
Others | Others |
C13-113-tri tail 是一种阳离子类脂化合物,可用于配制脂质纳米颗粒。 | |||
T60775 |
BB 0305179
|
Others | Others |
BB 0305179 (化合物 59) 抑制疏水结构域缺失的特定 PrP 突变体的毒性,是有效的抗朊病毒剂 (IC50 = 4.7 μM)。 | |||
T69911 |
CU-6PMN
|
Others | Others |
CU-6PM is a new fluorescent RXR agonist. CU-6PMN was designed based on the fact that umbelliferone emits strong fluorescence in a hydrophilic environment, but the fluorescence intensity decreases in hydrophobic environments such as the interior of proteins. The developed assay CU-6PMN enabled screening of rexinoids to be performed easily within a few hours by monitoring changes of fluorescence intensity with widely available fluorescence microplate readers, without the need for processes such a... | |||
TP2510 |
CAY10679
N,N'-bis(glycyl-glycine)-hexane-1,6-Dicarboxyamide |
Others | Others |
CAY10679, an anionic oligopeptide-based bola-amphiphile, features a central hexane segment bordered by a glycylglycine group at each end, establishing pronounced hydrophilic and hydrophobic regions. This amphiphilic peptide's propensity for self-assembling into microtubes in aqueous acidic solutions has been explored. Such bola-amphiphiles hold significant potential in the development of nanotubes, nanovesicles, nanowires, and nanocarriers for drug delivery, among various bionanotechnology appli... | |||
T63285 |
Antifungal agent 40
|
Others | Others |
Antifungal agent 40 是抗真菌剂,能够延伸到 C.alb.CYP51 的狭窄疏水口袋 II 中,可抑制 lanosterol 14α-demethylase (CYP51) 的活性,对生物膜的形成具有抑制作用。 | |||
T70646 |
Deltarasin HCl
|
Others | Others |
Deltarasin is a high affinity PDEδ-KRAS interaction inhibitor. Deltarasin can inhibit KRAS-PDEδ interactions by binding to a hydrophobic pocket on PDEδ, resulting in the impairment of cell growth, KRAS activity, and RAS/RAF signaling in human pancreatic ductal adenocarcinoma cell lines. The anti-cancer cell activity of deltarasin can be enhanced by simultaneously blocking tumor protective" autophagy | |||
T78387 |
5-Dodecanoylaminofluorescein
|
||
5-Dodecanoylaminofluorescein为亲脂性荧光探针,属于游离脂肪酸的荧光素衍生物。该探针应用于膜流动性分析与洗涤剂临界胶束浓度测定,并可用于制备药物递送用的疏水性纳米球。 | |||
T83936 |
LL-K9-3
|
Others | Others |
LL-K9-3是一种基于选择性疏水标记技术(HyT)的CDK9-cyclin T1复合物降解剂(DC50值分别为cyclin T1的589 nM和CDK9的662 nM)。它由CDK9抑制剂SNS 032和一个糖基连接器连接到疏水标记组成。LL-K9-3不会降解其他CDKs(CDK1、2、4、5、6和7)。在22RV1细胞中,LL-K9-3通过诱导CDK9和cyclin T1的选择性和同步降解,降低雄激素受体(AR)和cMyc的表达。 | |||
T64037 |
CYP3A4-IN-2
|
Others | Others |
CYP3A4-IN-2 是细胞色素 P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) 的特异性抑制剂 (IC50: 0.055 μM)。CYP3A4-IN-2 是利托那韦类似物,与利托那韦相比,其 R2 侧基的疏水性更高,抑制作用更强。CYP3A4-IN-2 能够作为免疫抑制剂及抗病毒剂。 | |||
T79700 |
α-Glucosidase-IN-32
|
Glucosidase | Metabolism |
α-Glucosidase-IN-32 (compound f26),是一种口服有效的α-glucosidase抑制剂,具有可逆、非竞争性特点,IC50值为3.07 μM。该化合物通过与α-glucosidase形成氢键和疏水相互作用,以改变其构象和二级结构,从而抑制酶活性。α-Glucosidase-IN-32 主要用于糖尿病研究。 | |||
T36956 |
Bis-ANS dipotassium
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid,bis-ANS (potassium salt) |
||
bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.[1] Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.[2] bis-ANS has an excitation maxima of 390 nm.[3] It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8032 |
4-Pentenoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
4-Pentenoic acid 是内源性代谢产物的一种。 | |||
T4889 |
2,6-Diaminoheptanedioic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。 | |||
T8098 |
γ-Hexalactone
γ-caprolactone,gamma-己内酯,γ-己内酯 |
Others | Others |
γ-Hexalactone (γ-caprolactone) 是一种存在成熟水果中的 gamma 内酯。它会导致 DNA 损伤,可用作对氧磷酶 1 的底物 (PON1)。 | |||
T36439 |
Gramicidin A
|
Antibacterial; HIF; Parasite | Angiogenesis; Chromatin/Epigenetic; Microbiology/Virology |
Gramicidin A 是一种从从 B. brevis 分离出来的多肽类抗生素。Gramicidin A 是一种高度疏水的通道形成离子载体,在人工膜中形成一价阳离子可渗透的通道。Gramicidin A 诱导缺氧诱导因子 1α (HIF-1α) 的降解,并能降低人肾细胞癌小鼠异种移植模型的生长。Gramicidin A 具有抗菌、抗疟活性以及溶血活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03962 |
AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF |
Human | HEK293 Cells |
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... | |||
TMPY-03118 |
ORM2 Protein, Human, Recombinant (His)
AGP-B',ORM2,orosomucoid 2,AGP-B,AGP2 |
Human | HEK293 Cells |
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins can be found in gram-negative bacteria, vertebrate cells, and invertebrate cells, and plants. They are associated with many biological processes. ORM2 functions as a transport protein in the bloodstream. It is expressed by the liver and s... | |||
TMPY-01806 |
CD9 Protein, Human, Recombinant (His)
BTCC-1,DRAP-27,TSPAN29,MRP-1,CD9 molecule,MIC3,TSPAN-29 |
Human | HEK293 Cells |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPH-01633 |
MMP-12 Protein, Human, Recombinant (His)
MMP12,Macrophage metalloelastase,Matrix metalloproteinase-12... |
Human | E. coli |
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. MMP-12 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P39900. | |||
TMPH-02682 |
GSTM3 Protein, Mouse, Recombinant (His & Myc)
GST class-mu 3,Gstm3,Glutathione S-transferase Mu 3,Glutathi... |
Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GSTM3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.0 kDa and the accession number is P19639. | |||
TMPJ-00888 |
ANXA7 Protein, Human, Recombinant
Annexin A7,Annexin-7,Synexin,ANXA7,Annexin VII,SNX,ANX7 |
Human | E. coli |
Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal region is composed of alternating hydrophobic and hydrophilic segments. Annexin A7 is a calcium/phospholipid-binding protein with diverse properties including voltage-sensitive calcium channel activity and promotes membrane fusion and is also involved in exocytosis. | |||
TMPH-03138 |
GST Protein, Plasmodium falciparum, Recombinant (His)
|
Plasmodium falciparum | P. pastoris (Yeast) |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin). GST Protein, Plasmodium falciparum, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 27.3 kDa and the accession number is Q8MU52. | |||
TMPH-01806 |
OBP2A Protein, Human, Recombinant (C114S & K127N, His & SUMO)
Odorant-binding protein 2a,OBP2A,Odorant-binding protein IIa |
Human | E. coli |
Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids. OBP2A Protein, Human, Recombinant (C114S & K127N, His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.8 kDa and the accession number is Q9NY56. | |||
TMPJ-00942 |
MMP-12 Protein, Mouse, Recombinant (His)
Mme,Mmp12,MMP-12,Mmel,Matrix metalloproteinase-12,Macrophage... |
Mouse | HEK293 Cells |
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. | |||
TMPJ-00529 |
FABP6 Protein, Human, Recombinant (His)
Ileal Lipid-Binding Protein,I-BABP,Intestinal Bile Acid-Bind... |
Human | E. coli |
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level)... | |||
TMPJ-01356 |
NECAP2 Protein, Human, Recombinant (His)
NECAP endocytosis associated protein 2,Adaptin ear-binding c... |
Human | E. coli |
NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3. | |||
TMPH-01291 |
ERVK-7 Protein, Human, Recombinant (His)
Endogenous retrovirus group K member 7 Env polyprotein,HERV-... |
Human | E. coli |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane. | |||
TMPH-03583 |
Extracellular elastase Protein, S. epidermidis, Recombinant (His & Myc)
sepA,Extracellular elastase,SEPP1 |
Staphylococcus epidermidis | E. coli |
Protease that has a low substrate specificity. Glucagon is preferentially cleaved between aromatic (Phe) and hydrophobic (Val) amino acids. Hydrolyzes casein and elastin. Extracellular elastase Protein, S. epidermidis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.7 kDa and the accession number is P0C0Q4. | |||
TMPH-02621 |
DAO Protein, Mouse, Recombinant (His)
DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase |
Mouse | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system... | |||
TMPH-01398 |
GSTP1 Protein, Human, Recombinant (E. coli, His)
GSTP1,Glutathione S-transferase P,GSTP1-1,GST class-pi |
Human | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mo... | |||
TMPH-01399 |
GSTP1 Protein, Human, Recombinant (His)
GST class-pi,GSTP1,Glutathione S-transferase P,GSTP1-1 |
Human | P. pastoris (Yeast) |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.2 kDa and... | |||
TMPH-02683 |
GSTP1 Protein, Mouse, Recombinant (His & SUMO)
Gstp1,GST-piB,GST class-pi,Preadipocyte growth factor,GST YF... |
Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. | |||
TMPH-01290 |
ERVK-6 Protein, Human, Recombinant (His)
HERV-K(HML-2.HOM) envelope protein,ERVK-6,HERV-K(C7) envelop... |
Human | Baculovirus Insect Cells |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane... | |||
TMPY-00029 |
TM4SF2/TSPAN7 Protein, Rat, Recombinant (His)
tetraspanin 7 |
Rat | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-03862 |
TM4SF2/TSPAN7 Protein, Human, Recombinant (His)
TM4SF2,A15,MXS1,tetraspanin 7,TALLA-1,CCG-B7,CD231,DXS1692E,... |
Human | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-01878 |
L-FABP Protein, Human, Recombinant (His)
fatty acid binding protein 1, liver,FABPL,L-FABP |
Human | E. coli |
Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is t... | |||
TMPY-03978 |
TSPAN31 Protein, Human, Recombinant (mFc)
tetraspanin 31,SAS |
Human | HEK293 Cells |
TSPAN31 is a member of the transmembrane 4 superfamily. Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. They mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN31 is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. | |||
TMPH-01041 |
Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)
CPAH,CPA6,Carboxypeptidase A6 |
Human | E. coli |
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine. Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular w... | |||
TMPH-00159 |
Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO)
subC,Subtilisin Carlsberg |
Bacillus licheniformis | E. coli |
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 substrate position. May play an important role in the degradation of feather keratin. Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 42.0 kDa and the ac... | |||
TMPH-01289 |
ERVK-6 Protein, Human, Recombinant (E. coli, His)
HERV-K108 envelope protein,Endogenous retrovirus group K mem... |
Human | E. coli |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane... | |||
TMPJ-01092 |
MGAT2 Protein, Human, Recombinant (His)
Alpha-1,Mannoside Acetylglucosaminyltransferase 2,6-Mannosyl... |
Human | HEK293 Cells |
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A. | |||
TMPY-03930 |
TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (mFc)
tetraspanin 7 |
Cynomolgus | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPH-03276 |
DAO Protein, Rat, Recombinant (His & Myc)
D-amino-acid oxidase,Dao1,DAMOX,DAO,DAAO |
Rat | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy... | |||
TMPJ-00913 |
MPZ Protein, Human, Recombinant (His)
Myelin Peripheral Protein,Myelin Protein P0,MPZ,Myelin Prote... |
Human | HEK293 Cells |
Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain... | |||
TMPH-01640 |
MRGPRX2 Protein, Human, Recombinant (His)
Mas-related G-protein coupled receptor member X2,MRGPRX2 |
Human | E. coli |
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway c... | |||
TMPJ-01006 |
KPNA2 Protein, Human, Recombinant (His)
RCH1,SRP1-Alpha,Importin Subunit Alpha-2,Importin Subunit α-... |
Human | E. coli |
Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nu... | |||
TMPY-03864 |
CRABP1 Protein, Human, Recombinant
CRABP,CRABP-I,RBP5,cellular retinoic acid binding protein 1,... |
Human | E. coli |
CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. It forms a beta-barrel structure which accommodates hydrophobic ligands in its interior. | |||
TMPJ-01268 |
ERP27 Protein, Human, Recombinant (His)
C12orf46,ER Protein 27,Endoplasmic Reticulum Resident Protei... |
Human | HEK293 Cells |
Endoplasmic reticulum resident protein 27, also known as ER protein 27, C12orf46 and ERP27, is an endoplasmic reticulum luminal protein which is a member of the protein disulfide isomerase family. ERP27 contains one thioredoxin domain and does not contain a CXXC active site motif. ERP27 is widely expressed in many tissues; it has highest expression in pancreas, with lower levels in spleen, lung, kidney, thymus, and bone marrow. ERP27 interacts with PDIA3 and binds somatostatin-14 via hydrophobic... | |||
TMPY-03833 |
TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (His)
tetraspanin 7 |
Cynomolgus | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPY-03450 |
GSTK1 Protein, Human, Recombinant
glutathione S-transferase κ1,GST,glutathione S-transferase k... |
Human | E. coli |
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body. GSTK1(glutathione S-transferase kappa 1) is localized to the peroxisome and catalyzes the... | |||
TMPY-03330 |
BPHL Protein, Human, Recombinant (His)
biphenyl hydrolase-like (serine hydrolase),VACVASE,MCNAA,BPH... |
Human | E. coli |
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ... | |||
TMPJ-00111 |
CD9 Protein, Human, Recombinant (hFc)
CD9 molecule,TSPAN29,BTCC1,CD9 antigen,CD9,MIC3,MRP1,DRAP-27... |
Human | HEK293 Cells |
CD9, also known as Tspan29, 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 is a cell surface glycoprotein with 4 hydrophobic domains that is described to complex with integrins and other transmembrane 4 superfamily members. The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activat... | |||
TMPH-02345 |
Influenza A H1N1 (train A/Hickox/1940) Hemagglutinin/HA Protein (His & SUMO)
HA,Hemagglutinin |
H1N1 | E. coli |
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the e... | |||
TMPY-03417 |
ACBD7 Protein, Human, Recombinant (His)
acyl-CoA binding domain containing 7,ACBD7,bA455B2.2,RP11-45... |
Human | E. coli |
ACBD7, acyl-CoA-binding domain-containing protein 7, is a small (1 Kd) protein that contains 1 ACB (acyl-CoA-binding) domain. The ACB domain consists of four alpha-helices arranged in a bowl shape with a highly exposed acyl-CoA-binding site. The ligand is bound through specific interactions with residues on the protein, most notably several conserved positive charges that interact with the phosphate group on the adenosine-3'phosphate moiety, and the acyl chain is sandwiched between the hydrop... | |||
TMPY-04945 |
Der p 2 Protein, Dermatophagoides pteronyssinus, Recombinant (His)
|
Dermatophagoides pteronyssinus | E. coli |
Hypersensitivity to house dust mite (Dermatophagoides sp.) allergens is one of the most common allergic reactions in the world. The house dust mite allergen, Der p 2, is a major allergen and 80–90% of patients who react to mite extract, react specifically to this protein or its homologues. Although it is well characterized in terms of allergenicity, there is still some ambiguity in terms of its biological function. Three-dimensional structural analysis of Der p 2 and its close homologues indicat... | |||
TMPJ-01008 |
THOP1 Protein, Human, Recombinant (His)
THOP1,MP78,Thimet Oligopeptidase,Endopeptidase 24.15 |
Human | E. coli |
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degrada... | |||
TMPY-03871 |
TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His)
AI323365,Tm4sf2,PE31,A15,R74651,TALLA,Mxs1,Cd231,1200014P11R... |
Mouse | HEK293 Cells |
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4... | |||
TMPH-01855 |
PEX19 Protein, Human, Recombinant (GST)
PEX19,33 kDa housekeeping protein,Peroxisomal farnesylated p... |
Human | E. coli |
Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. PEX19 Protein, ... | |||
TMPJ-00584 |
Bc1-w Protein, Human, Recombinant (His)
Apoptosis Regulator Bcl-W,KIAA0271,Bcl-2-Like Protein 2,Bcl2... |
Human | E. coli |
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone... | |||
TMPH-00534 |
Gelatinase Protein, Enterococcus faecalis, Recombinant (His & SUMO)
Gelatinase,gelE,Coccolysin |
Enterococcus faecalis | E. coli |
Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentially hydrolyzes the 24-Phe-|-Phe-25 bond in the insulin B-chain, followed by the 5-His-|-Leu-6 bond. Inactivates endothelin-1, primarily by cleavage of the 5-Ser-|-Leu-6 and 16-His-|-Leu-17 bonds. Hydrolyzes the alpha chain of C3 to generate a C3b-like protein. Inhibits complement-m... | |||
TMPJ-00853 |
DAO Protein, Human, Recombinant (His)
D-Amino-Acid Oxidase,DAMOX,DAAO,DAO |
Human | E. coli |
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a... | |||
TMPY-02285 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein
NS2 Protein |
H1N1 | E. coli |
Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a hydrophobic, transmembrane protein that is required not only for NS2-NS3 cleavage but also for infectious virus production.NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and ant... | |||
TMPH-01299 |
EMC4 Protein, Human, Recombinant (His)
TMEM85,EMC4,ER membrane protein complex subunit 4,Transmembr... |
Human | E. coli |
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spann... | |||
TMPY-03276 |
BLBP Protein, Human, Recombinant
fatty acid binding protein 7, brain,FABPB,MRG,B-FABP,BLBP,RP... |
Human | E. coli |
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expre... | |||
TMPY-01563 |
PMP2 Protein, Human, Recombinant (His)
MP2,FABP8,peripheral myelin protein 2,P2,M-FABP |
Human | E. coli |
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells ... | |||
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