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Search Results for " enantiomer "

Targets Recommended: PARP

298

抑制剂 & 化合物

24

天然产物

1

化合物库

1

重组蛋白

13

同位素标记化合物

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Cat. No.	Product Name
L5800	药物代谢杂质库		197 compounds
	197 种药物异构体/代谢产物的特有集合，可用于高通量、高内涵筛选；

化合物库

药物代谢杂质库

Cat.No: L5800

Compounds: 197

Cat. No.	Product Name	Target	Signaling Pathways
T12064	Niraparib (R-enantiomer) MK 4827 (R-enantiomer),Niraparib R-enantiomer	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib R-enantiomer (MK 4827 R-enantiomer) 是一种 PARP1抑制剂，IC50为 2.4 nM。
T12697	Refametinib R enantiomer RDEA119 R enantiomer,Refametinib R enantiomer,BAY 869766 R enantiomer	MEK	MAPK
	Refametinib R enantiomer (RDEA119 R enantiomer) 是一种 MEK 抑制剂，EC50为 2.0-15 nM。Refametinib R enantiomer 具有抗癌活性，可用于研究癌症。
T13140	Umbralisib R-enantiomer TGR-1202 R-enantiomer,RP5264 R-enantiomer	PI3K	PI3K/Akt/mTOR signaling
	Umbralisib R-enantiomer (RP5264 R-enantiomer) 是 PI3K 的δ型抑制剂，是 TGR-1202 活性较低的对映体。Umbralisib R-enantiomer 对δ型 pi3激酶的 IC50，至少比抑制剂对其他 PI3K 亚型(A， β和γ)的 IC50低20倍。
T15263	Selisistat R-enantiomer EX-527 (R-enantiomer)	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Selisistat R-enantiomer (EX-527 (R-enantiomer)) 是 Selisistat R 型对映体。Selisistat 是SIRT1的选择性抑制剂，IC50为98 nM。
T17102	Tipifarnib (S enantiomer) Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer	Transferase	Metabolism
	Tipifarnib S enantiomer ((S)-(-)-R-115777) 是Tipifarnib 的 S 型对映体，它比 Tipifarnib 特性低。其中 Tipifarnib 是farnesyltransferase 高效特异性抑制剂，IC50=0.6 nM。
T11129L	Duvelisib (R enantiomer) hydrochloride IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl	PI3K	PI3K/Akt/mTOR signaling
	Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) 是 PI3K 抑制剂。Duvelisib (R enantiomer) hydrochloride 是 Duvelisib 的活性较低的对映体。
T7058	Selisistat S-enantiomer EX-527 S-enantiomer,(1S)-6-氯-2,3,4,9-四氢-1H-咔唑-1-甲酰胺,EX-527 (S-enantiomer)	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Selisistat S-enantiomer (EX-527 S-enantiomer) 是一种选择性的SIRT1抑制剂，IC50值为 98 nM。
T12831	SAR405 R enantiomer	Others	Others
	SAR405 R enantiomer 是一种 PIK3C3/Vps34 抑制剂，也是活性低于 SAR405 的对映体。
T6156	Ruxolitinib (S enantiomer) S-Ruxolitinib,环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯,Ruxolitinib S enantiomer,INCB018424,INCB18424	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Ruxolitinib S enantiomer (INCB18424) 是 Ruxolitinib 的 S 型对映体，是一种JAK 抑制剂。
T19618	(R)-(-)-JQ1 Enantiomer (R)-(-)2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂环庚烷-6-基)乙酸叔丁酯	Epigenetic Reader Domain	Chromatin/Epigenetic
	(R)-(-)-JQ1 Enantiomer 是 (+)-JQ1 的立体异构体。 (+)-JQ1 是一种 BET 溴结构域抑制剂，对BRD4(1/2)的IC50 为 77 和 33 nM。
T9825	CORT-108297 Enantiomer	Others	Others
	CORT-108297 Enantiomer 是 CORT-108297 的对映体，CORT-108297是糖皮质激素受体的拮抗剂。
T7695	PNU-282987 S enantiomer free base	AChR	Neuroscience
	PNU-282987 S enantiomer free base 是 PNU-282987 的 S 型对映体，是 α7 烟碱乙酰胆碱受体的激动剂。
T67881	Acalabrutinib enantiomer R-Acalabrutinib	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	Acalabrutinib enantiomer (R-Acalabrutinib) 是一类属于布鲁顿酪氨酸激酶(BTK)抑制剂的化合物。Acalabrutinib enantiomer 可用于癌症、自身免疫性疾病和慢性炎症等领域的研究。
T10819	Cipropride S enantiomer	Others	Others
	Cipropride S enantiomer 是止吐药环普必利的S 对映体。
T19112L	Sacubitril Enantiomer 2R,4S-Sacubitril,LCZ 696杂质A,ahu377 isomer 2	Others	Others
	Sacubitril Enantiomer (ahu377 isomer 2) 是 Sacubitril 的对映体，它是一种脑啡肽酶抑制剂。
T80678	(S)-AK-242 (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242	Others	Others
	(S)-AK-242 ((S)-Resatorvid) 是一种细胞因子抑制剂，可用于治疗心脏病、自身免疫性疾病、炎症性疾病。
T22450	Tyrphostin B44, (+) enantiomer 酪氨酸磷酸化抑制剂AG 835	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tyrphostin B44, (+) enantiomer 是一种表皮生长因子受体 (EGFR) 激酶抑制剂，IC50 为 0.86 μM，活性低于 (-) 对映体。
T12274	Siremadlin (R Enantiomer) Siremadlin R Enantiomer,HDM201 R Enantiomer,NVP-HDM201 R Enantiomer	Others	Others
	Siremadlin R Enantiomer is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific inhibitor of MDM-2/p53.
T12200	Firsocostat S enantiomer ND-630 S enantiomer,NDI-010976 S enantiomer,GS-0976 S enantiomer	Others	Others
	Firsocostat S enantiomer is the less active S enantiomer of Firsocostat.
T11129	Duvelisib (R enantiomer) Duvelisib R enantiomer,IPI-145 R enantiomer,INK1197 R enantiomer	PI3K	PI3K/Akt/mTOR signaling
	Duvelisib R enantiomer (IPI-145 R enantiomer) 是一种 Duvelisib 的对映异构体，活性较低。它是一种 PI3K 抑制剂。
T11410	GLPG0492 (R enantiomer) GLPG0492 R enantiomer	Others	Others
	GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.
T11391	Gepotidacin S enantiomer GSK2140944 S enantiomer	Others	Others
	Gepotidacin S enantiomer is an S enantionmer of gepotidacin.
T11173	Elacestrant S enantiomer RAD1901 S enantiomer	Others	Others
	Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.
T11335	Fulvestrant (S enantiomer) ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer	Others	Others
	Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
T11334	Fulvestrant (R enantiomer) ICI 182780 R enantiomer,ZD 9238 R enantiomer,ZM 182780 R enantiomer,Fulvestrant R enantiomer	Others	Others
	Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
T10552	Bitopertin (R enantiomer) RO4917838 (R enantiomer),RG1678 (R enantiomer),Bitopertin R enantiomer	GlyT	Neuroscience
	Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
T13312	Seviteronel R enantiomer VT-464 (R enantiomer)	Others	Others
	Seviteronel R enantiomer is the R enantiomer of Seviteronel and is a potent inhibitor of CYP17 lyase (IC50: 69 nM for h-Lyase).
T13422L	Talarozole (R enantiomer) (R)-Talarozole,Talarozole R enantiomer	Others	Others
	Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid.
T13120	Tenalisib R Enantiomer RP6530 R Enantiomer	Others	Others
	Tenalisib R Enantiomer is an R enantiomer of Tenalisib .
T11156	Nazartinib S-enantiomer EGF816 (S-enantiomer)	Others	Others
	Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
T10465	Atuveciclib S-Enantiomer BAY-1143572 S-Enantiomer	CDK	Cell Cycle/Checkpoint
	Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) 是 BAY-1143572的 S-对映异构体，是一种有效的选择性 CDK9抑制剂，抑制 CDK9/CycT1，IC50为 16 nM。
T12775	RSV604 (R enantiomer) RSV604 R enantiomer	Others	Others
	RSV604 R enantiomer is the R-enantiomer of RSV604. RSV604 is a respiratory syncytial virus (RSV) replication inhibitor.
T10856	Cobimetinib (R-enantiomer) 考比替尼 (R 型对映体),XL-518 R-enantiomer,Cobimetinib R-enantiomer,GDC-0973 R-enantiomer	Others	Others
	Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.
T11173L	Elacestrant S enantiomer dihydrochloride RAD1901 S enantiomer dihydrochloride,RAD-1901 S enantiomer dihydrochloride,RAD 1901 S enantiomer dihydrochloride	Others	Others
	Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
T11662	INT-777 R-enantiomer S-EMCA R enantiomer	Others	Others
	INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.
T11627	IACS-8968 R-enantiomer IDO/TDO Inhibitor (R-enantiomer)	IDO	Metabolism
	IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).
T10252L	ADU-S100 enantiomer ammonium salt MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt	Others	Others
	ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100. ADU-S100 is an activator of the stimulator of interferon genes (STING).
T67880	NITD-609 Enantiomer	Others	Others
	NITD-609 Enantiomer 是 NITD-609 的对映体，NITD-609 是一种具有抗疟活性的螺酮类药物。
T11628	IACS-8968 S-enantiomer IDO/TDO Inhibitor (S-enantiomer)	IDO	Metabolism
	IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).
T9848	GSK2850163 (S enantiomer)	IRE1	Cell Cycle/Checkpoint
	GSK2850163 (S enantiomer) 是 GSK2850163 的无活性对映体。GSK2850163 是一种新型的肌醇需求酶-1α (IRE1a) 抑制剂。
T39541	THK5351 (R enantiomer)	Others	Others
	THK5351 R enantiomer is an R enantiomer of THK5351.
T41114	LIN28 inhibitor LI71 enantiomer	Others	Others
	LIN28 inhibitor LI71 enantiomer, the enantiomer of LIN28 inhibitor LI71，exhibits reduced activity compared to its parent compound. LIN28 inhibitor LI71 is a highly potent and cell-permeable inhibitor of LIN28, effectively blocking LIN28-mediated oligouridylation with an IC50 of 7 uM.
T22401	PNU-282987 S enantiomer hydrochloride (S)-PNU-282987 HCl	Others	Others
	(S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAC
T12915	Silvestrol aglycone (enantiomer)	Others	Others
	Silvestrol aglycone (enantiomer) is a cyclopenta benzofuran core phenol.
T11195	Enantiomer of Sofosbuvir	Others	Others
	Enantiomer of Sofosbuvir 是Sofosbuvir 的对映异构体，Sofosbuvir 是一种治疗慢性丙型肝炎的处方药，目前尚无enantiomer of Sofosbuvir 的生物活性报道。
T12067	MK-7246 S enantiomer	Others	Others
	MK-7246 S enantiomer is a potent and selective CRTH2 antagonist.
T12723	Ribocil-C R enantiomer	Others	Others
	Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.
T12203	Necrostatin 2 S enantiomer	Others	Others
	Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2
T11902	LY 344864 S-enantiomer	Others	Others
	LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.
T11841	Leu-AMS R enantiomer	Others	Others
	Leu-AMS R enantiomer 是 Leu-AMS 的 R 对映体。 Leu-AMS 是一种有效的亮氨酰-tRNA 合成酶 (LRS) 抑制剂，可抑制细菌的生长。

化合物

Niraparib (R-enantiomer)

Cat.No: T12064

Synonym: MK 4827 (R-enantiomer),Niraparib R-enantiomer

Target: PARP

Refametinib R enantiomer

Cat.No: T12697

Synonym: RDEA119 R enantiomer,Refametinib R enantiomer,BAY 869766 R enantiomer

Target: MEK

Umbralisib R-enantiomer

Cat.No: T13140

Synonym: TGR-1202 R-enantiomer,RP5264 R-enantiomer

Target: PI3K

Selisistat R-enantiomer

Cat.No: T15263

Synonym: EX-527 (R-enantiomer)

Target: Sirtuin

Tipifarnib (S enantiomer)

Cat.No: T17102

Synonym: Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer

Target: Transferase

Duvelisib (R enantiomer) hydrochloride

Cat.No: T11129L

Synonym: IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl

Target: PI3K

Selisistat S-enantiomer

Cat.No: T7058

Synonym: EX-527 S-enantiomer,(1S)-6-氯-2,3,4,9-四氢-1H-咔唑-1-甲酰胺,EX-527 (S-enantiomer)

Target: Sirtuin

SAR405 R enantiomer

Cat.No: T12831

Target: Others

Ruxolitinib (S enantiomer)

Cat.No: T6156

Synonym: S-Ruxolitinib,环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯,Ruxolitinib S enantiomer,INCB018424,INCB18424

Target: Tyrosine Kinases, JAK

(R)-(-)-JQ1 Enantiomer

Cat.No: T19618

Synonym: (R)-(-)2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂环庚烷-6-基)乙酸叔丁酯

Target: Epigenetic Reader Domain

CORT-108297 Enantiomer

Cat.No: T9825

Target: Others

PNU-282987 S enantiomer free base

Cat.No: T7695

Target: AChR

Acalabrutinib enantiomer

Cat.No: T67881

Synonym: R-Acalabrutinib

Target: BTK

Cipropride S enantiomer

Cat.No: T10819

Target: Others

Sacubitril Enantiomer

Cat.No: T19112L

Synonym: 2R,4S-Sacubitril,LCZ 696杂质A,ahu377 isomer 2

Target: Others

Cat.No: T80678

Synonym: (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242

Target: Others

Tyrphostin B44, (+) enantiomer

Cat.No: T22450

Synonym: 酪氨酸磷酸化抑制剂AG 835

Target: EGFR

Siremadlin (R Enantiomer)

Cat.No: T12274

Synonym: Siremadlin R Enantiomer,HDM201 R Enantiomer,NVP-HDM201 R Enantiomer

Target: Others

Firsocostat S enantiomer

Cat.No: T12200

Synonym: ND-630 S enantiomer,NDI-010976 S enantiomer,GS-0976 S enantiomer

Target: Others

Duvelisib (R enantiomer)

Cat.No: T11129

Synonym: Duvelisib R enantiomer,IPI-145 R enantiomer,INK1197 R enantiomer

Target: PI3K

GLPG0492 (R enantiomer)

Cat.No: T11410

Synonym: GLPG0492 R enantiomer

Target: Others

Gepotidacin S enantiomer

Cat.No: T11391

Synonym: GSK2140944 S enantiomer

Target: Others

Elacestrant S enantiomer

Cat.No: T11173

Synonym: RAD1901 S enantiomer

Target: Others

Fulvestrant (S enantiomer)

Cat.No: T11335

Synonym: ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer

Target: Others

Fulvestrant (R enantiomer)

Cat.No: T11334

Synonym: ICI 182780 R enantiomer,ZD 9238 R enantiomer,ZM 182780 R enantiomer,Fulvestrant R enantiomer

Target: Others

Bitopertin (R enantiomer)

Cat.No: T10552

Synonym: RO4917838 (R enantiomer),RG1678 (R enantiomer),Bitopertin R enantiomer

Target: GlyT

Seviteronel R enantiomer

Cat.No: T13312

Synonym: VT-464 (R enantiomer)

Target: Others

Talarozole (R enantiomer)

Cat.No: T13422L

Synonym: (R)-Talarozole,Talarozole R enantiomer

Target: Others

Tenalisib R Enantiomer

Cat.No: T13120

Synonym: RP6530 R Enantiomer

Target: Others

Nazartinib S-enantiomer

Cat.No: T11156

Synonym: EGF816 (S-enantiomer)

Target: Others

Atuveciclib S-Enantiomer

Cat.No: T10465

Synonym: BAY-1143572 S-Enantiomer

Target: CDK

RSV604 (R enantiomer)

Cat.No: T12775

Synonym: RSV604 R enantiomer

Target: Others

Cobimetinib (R-enantiomer)

Cat.No: T10856

Synonym: 考比替尼 (R 型对映体),XL-518 R-enantiomer,Cobimetinib R-enantiomer,GDC-0973 R-enantiomer

Target: Others

Elacestrant S enantiomer dihydrochloride

Cat.No: T11173L

Synonym: RAD1901 S enantiomer dihydrochloride,RAD-1901 S enantiomer dihydrochloride,RAD 1901 S enantiomer dihydrochloride

Target: Others

INT-777 R-enantiomer

Cat.No: T11662

Synonym: S-EMCA R enantiomer

Target: Others

IACS-8968 R-enantiomer

Cat.No: T11627

Synonym: IDO/TDO Inhibitor (R-enantiomer)

Target: IDO

ADU-S100 enantiomer ammonium salt

Cat.No: T10252L

Synonym: MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt

Target: Others

NITD-609 Enantiomer

Cat.No: T67880

Target: Others

IACS-8968 S-enantiomer

Cat.No: T11628

Synonym: IDO/TDO Inhibitor (S-enantiomer)

Target: IDO

GSK2850163 (S enantiomer)

Cat.No: T9848

Target: IRE1

THK5351 (R enantiomer)

Cat.No: T39541

Target: Others

LIN28 inhibitor LI71 enantiomer

Cat.No: T41114

Target: Others

PNU-282987 S enantiomer hydrochloride

Cat.No: T22401

Synonym: (S)-PNU-282987 HCl

Target: Others

Silvestrol aglycone (enantiomer)

Cat.No: T12915

Target: Others

Enantiomer of Sofosbuvir

Cat.No: T11195

Target: Others

MK-7246 S enantiomer

Cat.No: T12067

Target: Others

Ribocil-C R enantiomer

Cat.No: T12723

Target: Others

Necrostatin 2 S enantiomer

Cat.No: T12203

Target: Others

LY 344864 S-enantiomer

Cat.No: T11902

Target: Others

Leu-AMS R enantiomer

Cat.No: T11841

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5113	L-GLUCOSE L-葡萄糖,L-(-)-Glucose	Others	Others
	L-Glucose (L-(-)-Glucose) 是一种 D-glucose 的对映体，可促进食物的摄取。
T0185	Escitalopram Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Escitalopram (Seroplex) 是一种外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂，Ki=0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性，是一种研究抑郁症的抗抑郁药。
T5218	DL-Threitol	Others	Others
	DL-Threitol 是苏糖醇的 D-对映异构体。它具有作为人体代谢物的作用。它是 L-苏糖醇的对映异构体。
T20191	(-)-Camphoric acid (-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-	GluR	Neuroscience
	(-)-Camphoric acid (L-Camphoric acid) 是一种活性较低的樟脑酸对映异构体，樟脑酸可诱导 GluR 表达。
T10935	D-Glutamic acid (R)-Glutamic acid,D-谷氨酸	Endogenous Metabolite	Metabolism
	D-Glutamic acid ((R)-Glutamic acid) 是一种广泛用于药物和食品中的L-glutamic acid 对映异构体。
T1317	Cinchonidine 奎宁树,α-Quinidine,辛可尼丁,L-Cinchonidine	5-HT Receptor; Serotonin Transporter; Parasite	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Cinchonidine (L-Cinchonidine) 是在金鸡纳和角蒿中发现的一种生物碱，有抗疟活性。它是用于有机化学中不对称合成的砌块，是血清素转运蛋白的弱抑制剂。
T12796	S-Dihydrodaidzein S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one	Others	Others
	S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) 是一种 dihydrodaidzein 的 (S) 型对映体。其中 dihydrodaidzein 是一种可食用性植物雌激素。
T6396	(R)-(-)-Gossypol acetic acid (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate	BCL; Autophagy	Apoptosis; Autophagy
	(R)-(-)-Gossypol acetic acid (AT101 acetate) 是天然产物 Gossypol 的左旋异构体，与 Bcl-2、Bcl-xL 和 Mcl-1 结合，Ki 为 0.32 μM、0.48 μM 和 0.18 μM。
T38251	L-Uridine	Nucleoside Antimetabolite/Analog; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	L-Uridine 是从Polyporaceae fungus Poria cocos (Schw.)分离得到的正常 RNA 成分中的 D-尿苷的对映异构体，属于一种核苷，可充当核苷磷酸转移酶的磷酸受体。L-Uridine 具有潜在的抗病毒活性。
TN1448	(-)-Bornyl acetate L-(-)-Bornyl acetate,左旋乙酸冰片酯,Bornyl acetate,(-)-乙酸龙脑酯	p38 MAPK; NF-κB; JNK; Antifungal	MAPK; Microbiology/Virology; NF-κB
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) 是存在于牛膝草油中的一种具有抗真菌活性的 (+)-Bornyl acetate 低活性异构体。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
T6491	(-)-(S)-Equol (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。
TQ0109	Cephaeline dihydrochloride (-)-Cephaeline dihydrochloride,盐酸吐根酚碱,NSC 32944	P450	Metabolism
	(-)-Cephaeline (dihydrochloride) is an enantiomer of Cephaeline. Cephaeline is a selective CYP2D6 inhibitor (IC50: 121 μM).
T13464L	(-)-Ketoconazole (-)-R 41400,(-)-Ketoconazol	Others	Others
	(-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers.
TN7293	(+)-Secoisolariciresinol	Others	Others
	(+)-Secoisolariciresinol，是Secoisolariciresinol的一种(+)-对映体，归属于木脂素化合物。
T40529	(R)-(-)-1,2-Propanediol	Others	Others
	(R)-(-)-1,2-Propanediol is the (R)-enantiomer of 1,2-Propanediol, which is derived from glucose through the expression of NADH-linked glycerol dehydrogenase genes in Escherichia coli.
TN7546	(+)-Oxanthromicin	Others	Others
	(+)-Oxanthromicin, an enantiomer of the rare Streptomyces metabolite (−)-oxanthromicin, demonstrates inhibitory activity against K-Ras plasma membrane localization in MDCK cells, exhibiting an IC50 value of 62.5 μM.
T72509	Apoptosis inducer 5	Others	Others
	Apoptosisinducer 5 是一种木脂素对映异构体，存在于Crataegus pinnatifida 中。Apoptosisinducer 5 通过 Hep3B 细胞中的凋亡和自噬表现出细胞毒性作用。
TN7543	(S)-Laudanosine NSC 35045,L-(+)-Laudanosine,(+)-Laudanosine,L-Laudanosine	Others	Others
	(S)-Laudanosine, the (S) enantiomer of laudanosine, emerges as a metabolite from the neuromuscular blocking agents atracurium and cisatracurium. It functions by inhibiting prolyl endopeptidase and obstructing arachidonic acid- and collagen-induced aggregation in washed rabbit platelets.
T40576	(S)-Salsolidine	Others	Others
	(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boasting a K i value of 26 μM compared to the S form.
TN7296	(+)-Butin	Others	Others
	(+)-Butin为Butin的R型对映体，主要从黄檀心材中分离得到，是一种具有显著抗氧化、抗血小板及抗炎活性的生物活性黄酮类化合物。
T38497	(-)-Taxifolin (-)-二氢槲皮素,(-)-Dihydroquercetin	Others	Others
	(-)-Taxifolin is the less active enantiomer of Taxifolin, demonstrating vital anti-tyrosinase activity and notable inhibition against collagenase (IC50 = 193.3 μM). It is valued as an essential natural compound showing antifibrotic potential, while also acting as a capable free radical scavenger and possessing antioxidant capacity.
T83138	Aloinoside A
	Aloinoside A，一种可自黄芪分离的芦荟素，为Aloinoside B的对映异构体，应用于代谢研究的生物标志物。其通过大鼠肠道细菌代谢生成物包括芦荟苷、异芦荟苷及羟基代谢物。
TN4469	Lyoniresinol
	Lyoniresinol 是一种从 Tarenna attenuata 分离出来的木质素，具有清除自由基的活性（IC50为82.4μM）和 DPPH 的抗氧化活性，显示出抗黑色素生成活性。Lyoniresinol 有强烈的苦味，而其对映体(-)-Lyoniresinol 是无味的。

天然产物

Cat.No: T5113

Synonym: L-葡萄糖,L-(-)-Glucose

Target: Others

Cat.No: T0185

Synonym: Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

Cat.No: T5218

Target: Others

(-)-Camphoric acid

Cat.No: T20191

Synonym: (-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-

Target: GluR

D-Glutamic acid

Cat.No: T10935

Synonym: (R)-Glutamic acid,D-谷氨酸

Target: Endogenous Metabolite

Cat.No: T1317

Synonym: 奎宁树,α-Quinidine,辛可尼丁,L-Cinchonidine

Target: 5-HT Receptor, Serotonin Transporter, Parasite

S-Dihydrodaidzein

Cat.No: T12796

Synonym: S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

Target: Others

(R)-(-)-Gossypol acetic acid

Cat.No: T6396

Synonym: (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate

Target: BCL, Autophagy

Cat.No: T38251

Target: Nucleoside Antimetabolite/Analog, Antibiotic

(-)-Bornyl acetate

Cat.No: TN1448

Synonym: L-(-)-Bornyl acetate,左旋乙酸冰片酯,Bornyl acetate,(-)-乙酸龙脑酯

Target: p38 MAPK, NF-κB, JNK, Antifungal

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Cat.No: T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Cephaeline dihydrochloride

Cat.No: TQ0109

Synonym: (-)-Cephaeline dihydrochloride,盐酸吐根酚碱,NSC 32944

Target: P450

(-)-Ketoconazole

Cat.No: T13464L

Synonym: (-)-R 41400,(-)-Ketoconazol

Target: Others

(+)-Secoisolariciresinol

Cat.No: TN7293

Target: Others

(R)-(-)-1,2-Propanediol

Cat.No: T40529

Target: Others

(+)-Oxanthromicin

Cat.No: TN7546

Target: Others

Apoptosis inducer 5

Cat.No: T72509

Target: Others

(S)-Laudanosine

Cat.No: TN7543

Synonym: NSC 35045,L-(+)-Laudanosine,(+)-Laudanosine,L-Laudanosine

Target: Others

(S)-Salsolidine

Cat.No: T40576

Target: Others

Cat.No: TN7296

Target: Others

Cat.No: T38497

Synonym: (-)-二氢槲皮素,(-)-Dihydroquercetin

Target: Others

Cat.No: T83138

Cat.No: TN4469

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00178	AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) N-acyl homoserine lactonase AiiA,AHL-lactonase AiiA	Bacillus thuringiensis subsp. kurstaki	E. coli
	Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.7 kDa and the accession number is P0CJ63.

重组蛋白

AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc)

Cat.No: TMPH-00178

Species: Bacillus thuringiensis subsp. kurstaki

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T27210	DRX-065 DRX 065,DRX065,deuterated R-enantiomer of pioglitazone
	DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects, and glucose lowering effects) with
TMIJ-0155	rac-Aprepitant-d4 (enantiomer)
	rac-Aprepitant-d4 (enantiomer) 是 rac-Aprepitant 的氘代化合物。rac-Aprepitant 的 CAS 号为 170729-80-3。
TMIJ-0098	threo-Hydrobupropion-d9 HCl（enantiomer）
	threo-Hydrobupropion-d9 HCl（enantiomer）是 threo-Hydrobupropion HCl 的氘代化合物。
TMIJ-0169	erythro-Hydro Bupropion-d9 HCl（enantiomer）
	erythro-Hydro Bupropion-d9 HCl（enantiomer）是 erythro-Hydro Bupropion HCl 的氘代化合物。
TMIJ-0188	(±)-Voriconazole-d3 (Mixture of Enantiomers)
	(±)-Voriconazole-d3 (Mixture of Enantiomers) 是 (±)-Voriconazole 的氘代化合物。(±)-Voriconazole 的 CAS 号为 188416-29-7。
T12638	(R)-Praziquantel-d11 (R)-吡喹酮 D11,(R)-Praziquantel D11	5-HT Receptor	GPCR/G Protein; Neuroscience
	(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist
T12656	(Rac)-Apremilast D5 (Rac)-CC-10004 D5	Others	Others
	(Rac)-Apremilast D5 is a deuterium-labeled version of the enantiomer (R)-Apremilast, also known as (R)-CC-10004, which itself is one specific form of Apremilast.
T12648	(R)-VX-984 (R)-M9831	Others	Others
	(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent inhibitor of DNA-PK.
T12800	(S)-(+)-Ibuprofen D3 (S)-Ibuprofen D3	COX	Immunology/Inflammation; Neuroscience
	(S)-(+)-Ibuprofen D3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen ,it is an inhibitor of COX-1 and COX-2 activity (IC50s of 2.1 μM and 1.6 μM).
TMIJ-0231	Hydroxy Pentoxifylline-d6 rac-Lisofylline-d6
	Hydroxy Pentoxifylline-d6 是 Hydroxy Pentoxifylline 的氘代化合物。Hydroxy Pentoxifylline 的 CAS 号为 6493-06-7。(±)-Lisofylline 是一种对映异构体特异性、烷基取代的甲基黄嘌呤，在下调白细胞活化方面具有特异性和有效的活性。它是一种抗炎剂。
TMID-0190	Milnacipran-d10 Hydrochloride
	Milnacipran-d10 Hydrochloride 是 Milnacipran Hydrochloride 的氘代化合物。Milnacipran Hydrochloride 的 CAS 号为 101152-94-7。Milnacipran hydrochloride 是一种5-羟色胺-去甲肾上腺素重吸收抑制剂（SNRI），可用于纤维肌痛的研究。
TMIJ-0141	(S)-Amlodipine-d4
	(S)-Amlodipine-d4 是 (S)-Amlodipine 的氘代化合物。(S)-Amlodipine 的 CAS 号为 103129-82-4。Levamlodipine 是一种二氢吡啶钙通道阻滞剂，具有舒张血管的作用，可用于高血压和心绞痛的研究。
TMIH-0159	Citalopram-d6
	Citalopram-d6 是 Citalopram 的氘代化合物。Citalopram 的 CAS 号为 59729-33-8。Citalopram (Lu 10-171) 是一种具有口服活性的、选择性的血清素再摄取抑制剂 (SSRI)，是一种选择性5-羟色胺再摄取抑制剂，是一种 S(+)-对映体 (Escitalopram) 和 R(-)-对映体的外消旋混合物。Citalopram 具有抗抑郁活性，可增强血清素能神经传递，可用于研究老年痴呆。

同位素标记化合物

Cat.No: T27210

Synonym: DRX 065,DRX065,deuterated R-enantiomer of pioglitazone

rac-Aprepitant-d4 (enantiomer)

Cat.No: TMIJ-0155

threo-Hydrobupropion-d9 HCl（enantiomer）

Cat.No: TMIJ-0098

erythro-Hydro Bupropion-d9 HCl（enantiomer）

Cat.No: TMIJ-0169

(±)-Voriconazole-d3 (Mixture of Enantiomers)

Cat.No: TMIJ-0188

(R)-Praziquantel-d11

Cat.No: T12638

Synonym: (R)-吡喹酮 D11,(R)-Praziquantel D11

Target: 5-HT Receptor

(Rac)-Apremilast D5

Cat.No: T12656

Synonym: (Rac)-CC-10004 D5

Target: Others

Cat.No: T12648

Synonym: (R)-M9831

Target: Others

(S)-(+)-Ibuprofen D3

Cat.No: T12800

Synonym: (S)-Ibuprofen D3

Target: COX

Hydroxy Pentoxifylline-d6

Cat.No: TMIJ-0231

Synonym: rac-Lisofylline-d6

Milnacipran-d10 Hydrochloride

Cat.No: TMID-0190

(S)-Amlodipine-d4

Cat.No: TMIJ-0141

Cat.No: TMIH-0159

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