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Search Results for " combination "

Targets Recommended: Others

224

抑制剂 & 化合物

30

天然产物

12

化合物库

1

TargetMol 试剂盒

13

重组蛋白

10

同位素标记化合物

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Cat. No.	Product Name
L4500	抗真菌库		252 compounds
	252 个抗真菌活性化合物的独特集合，包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物，是相关疾病药物筛选的有效工具。
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L4000	经典已知活性库		14439 compounds
	14439 个已知活性化合物的集合，可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认；
L1000	上市药物库		2808 compounds
	2808 个上市药物化合物集合，可用于高通量筛选和高内涵筛选；
L1010	FDA上市及药典收录分子库		3158 compounds
	3158 个上市及药典分子集合，可用于高通量筛选和高内涵筛选；
L5100	含氟化合物库		574 compounds
	574 个含氟化合物的独特集合，可用于高通量筛选和高内涵筛选；
L7100	抗肥胖化合物库		2247 compounds
	2247 个抗肥胖化合物的独特集合，可用于高通量筛选和高内涵筛选；
L6610	抗感染天然产物库		1060 compounds
	1060 个抗感染相关的天然产物集合，是药物开发、药理研究的有效工具；
L2190	抗肺癌化合物库		1702 compounds
	1702 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
L2560	代谢化合物库		2320 compounds
	2320 种代谢途径相关的化合物，可用于高通量和高内涵筛选。
L9840	抗阿尔茨海默症化合物库		986 compounds
	986 种阿尔茨海默症相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

Cat.No: L4500

Compounds: 252

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

经典已知活性库

Cat.No: L4000

Compounds: 14439

上市药物库

Cat.No: L1000

Compounds: 2808

FDA上市及药典收录分子库

Cat.No: L1010

Compounds: 3158

含氟化合物库

Cat.No: L5100

Compounds: 574

抗肥胖化合物库

Cat.No: L7100

Compounds: 2247

抗感染天然产物库

Cat.No: L6610

Compounds: 1060

抗肺癌化合物库

Cat.No: L2190

Compounds: 1702

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

代谢化合物库

Cat.No: L2560

Compounds: 2320

抗阿尔茨海默症化合物库

Cat.No: L9840

Compounds: 986

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0052	Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile 青霉素-链霉素-两性霉素B三抗溶液（100×），灭菌	Solution in bottle

TargetMol 试剂盒

青霉素-链霉素-两性霉素B三抗溶液（100×），灭菌

Cat.No: C0052

Cat. No.	Product Name	Target	Signaling Pathways
T23757	Ascorbic acid, rutoside drug combination Rutinoscorbin,Rutascorbin,Ruta C 60,Cerutin	Others	Others
	Ascorbic acid, rutoside drug combination is used for treating diabetic retinopathy.
T12829	Salmeterol 沙美特罗,GR33343X	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Salmeterol (GR33343X) 是一种选择性的人β2肾上腺素受体激动剂。它能够有效刺激 cAMP 积累，作用于 CHO 细胞，对人β2，β1和β3肾上腺素受体的 pEC50分别为 9.6、6.1 和 5.9。
T7614	Eniluracil GW776C85,5-Ethynyluracil	Others	Others
	Eniluracil (GW776C85) 是不可逆的二氢嘧啶脱氢酶(DPD)抑制剂，是一种尿嘧啶类似物，能够使 5-FU 的口服生物利用度提高到 100%，促进均匀吸收和可预测的毒性。
T3661	Citarinostat ACY241,HDAC-IN-2	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Citarinostat (ACY241) 是一种强效、选择性和口服组蛋白脱乙酰酶 (HDAC) 抑制剂，具有抗肿瘤活性，对 HDAC1、HDAC2、HDAC3、HDAC6 和 HDAC8 的 IC50分别为 35、45、46、2.6 和 137 nM。
T7744	Piperaquine tetraphosphate tetrahydrate 4,4'-(1,3-丙烷双-4,1-哌嗪基)双(7-氯喹啉)磷酸盐水合物,四磷酸哌喹四水合物	Parasite	Microbiology/Virology
	Piperaquine tetraphosphate tetrahydrate 是一种双喹啉抗寄生虫剂，可与青蒿素联用研究抗疟。
T6653	Salmeterol Xinafoate Salmetedur,昔美酸沙美特罗,沙美特罗昔萘酸酯,GR 33343X xinafoate,Arial	HIV Protease; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Salmeterol Xinafoate (GR 33343X xinafoate) 是选择性人β2肾上腺素受体激动剂。Salmeterol 有效刺激 cAMP 积累，能够作用于 CHO 细胞，对人β2，β1和β3肾上腺素受体的 pEC50分别为 9.6、6.1 和 5.9。
T7532	Piperaquine	Parasite	Microbiology/Virology
	Piperaquine 是一种双喹啉化合物，可抑制来自疟疾感染患者的恶性疟原虫分离株的离体生长，IC50 范围为 11.8-217.3 nM。
T31088	CPX-351 Cytarabine/daunonubicin,Vyxeos,CPX 351,Daunonubicin/cytarabine	Others	Others
	CPX-351 is a Liposomal-encapsulated combination of daunorubicin and cytarabine for the treatment of newly diagnosed tAML or AML with myelodysplasia-related changes (AML-MRCs).
T3266	Lumefantrine Benflumetol,dl-Benflumelol,苯芴醇	Others; Parasite; Autophagy	Autophagy; Microbiology/Virology; Others
	Lumefantrine (dl-Benflumelol) 是一种抗疟药，用于治疗急性单纯性疟疾。与Artemether 联用，可提高疗效。
T2554	Etofibrate	Others	Others
	Etofibrate 是烟酸和氯贝酸的醚二醇-1,2 二酯。它是动物和人类中一种有效的降血脂剂。
T1430	Betamipron CS-443,N-Benzoyl-β-alanine,倍他米隆	Antibacterial; Antibiotic	Microbiology/Virology
	Betamipron (CS-443) 与Panipenem 联用，可抑制Panipenem 摄取进入肾小管，防止肾毒性。
T2239L	Raltegravir 雷特格韦,MK-0518	HIV Protease; Integrase	Microbiology/Virology; Proteases/Proteasome
	Raltegravir (MK-0518) 是一种HIV 整合酶抑制剂。
T63166L	(S, R)-LSN 3318839 (S, R)-LSN 3318839(Isomer-2764704-18-7)	Glucagon Receptor	GPCR/G Protein

T7537	Norgestimate 炔诺肟酯,诺孕酯	Progesterone Receptor	Others
	Norgestimate 是一种具有口服活性、高度选择性的孕激素活性和较小雄激素作用的孕激素，是一种合成的孕激素类似物。它可用作口服的避孕药。
T27787L	L-797,591 hydrochloride L-797,591 hydrochloride(217480-24-5 Free base)	Others	Others
	L-797,591 hydrochloride 对生长抑素受体亚型 1 (SSTR1)有活性。L-797,591 hydrochloride 常与 AG1478 联合使用来增强表达 SSTR1的细胞中 p-ERK5的表达。L-797,591 hydrochloride 在共转染的细胞中显著增强了 p38的磷酸化，这一作用在与 AG1478联合处理时被逆转。
T14408	Azido-PEG1-CH2CO2H 4-哌啶酮缩乙二醇	Others; PROTAC Linker	Others; PROTAC
	Azido-PEG1-CH2CO2H 是属于 alkyl/ether 类的PROTAC linker，可用于合成 PROTAC BRD4 Degrader-1.
T65232	HEDTA N-(2-Hydroxyethyl)ethylenediaminetriacetic acid	Others	Others
	HEDTA 是一种螯合剂，常与柠檬酸联合用药来研究血液疾病和脑部血液应激。
T7045	Clonidine Nexiclon,Catapres,Kapvay,可乐定	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Clonidine (Kapvay) 是 alpha2 肾上腺素能激动剂。
T30686	Cafedrine l-Cafedrine,Cafedrin	Others	Others
	Cafedrine (Cafedrin) 存在于茶叶和咖啡中，对中枢神经的兴奋作用。Cafedrine 常与可肾上腺素固定 20：1 组合来研究急性低血压。
T3139	Sultamicillin Tosylate Bacimex,舒巴西林,舒他西林甲苯磺酸盐,Unacim orale	Antibacterial; Antibiotic	Microbiology/Virology
	Sultamicillin Tosylate (Unacim orale) 是一种口服活性 β-内酰胺酶抑制剂，具有抗菌活性。它是舒巴坦与氨苄西林的双酯的甲苯磺酸盐。
T0148L	Folinic Acid Calcium Salt Pentahydrate Folinic acid,亚叶酸钙五水合物,Leucovorin Calcium Pentahydrate,Leucovorin calcium salt pentahydrate	Others; Antifolate	Cell Cycle/Checkpoint; Others
	Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate) 是一种还原型叶酸，是一种解毒剂，通常与甲氨蝶呤 (MTX) 联用，以降低 MTX 诱导的毒性。
T35354	BSTFA-TMCS	Others	Others
	The combination of BSTFA and TMCS is the preferred reagent for trimethylsilylation of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids. TMCS increases the reactivity of BSTFA. BSTFA-TMCS has good solvent properties and can function as a silylation reagent without additional solvents.
T12632L	(S)-Mirtazapine (S)-6-Azamianserin,(S)-Org3770	5-HT Receptor	GPCR/G Protein; Neuroscience
	(S)-Mirtazapine ((S)-Org3770) 是 Mirtazapine 的 S(+)-对映体。(S)-Mirtazapine 是一种选择性 5-HT2 受体拮抗剂,具有促痛觉作用,常与Mirtazapine 的 R(-)-对映体混合使用来研究抑郁症。
T67964	Terflavoxate	Microtubule Associated	Cytoskeletal Signaling
	Terflavoxate 是一种新型的、具有口服活性的半合成的他汀类微管抑制剂，常与卡培他滨一起联合使用。Terflavoxate 用于癌症的研究。
T0996	Ethynodiol diacetate Ethynodiol acetate,双醋炔诺醇,8080 CB	Estrogen/progestogen Receptor; Progesterone Receptor	Endocrinology/Hormones; Others
	Ethynodiol diacetate (Ethynodiol acetate) 是一种可用作激素避孕药的甾体孕激素，具有相对较少或没有雄激素效果，而具有显著雌激素作用。
T76877	Vofatamab RG-7444,B-701,MFGR-1877S	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Vofatamab (B-701) 是一种全人源靶向 FGFR3 的单克隆抗体。Vofatamab 具有潜在的抗癌抗肿瘤活性，常与其他化合物联用来治疗癌症。
T1119	Rasagiline 雷沙吉兰,AGN1135,TVP1012	BCL; MAO; Monoamine Oxidase	Apoptosis; Metabolism; Neuroscience
	Rasagiline (AGN1135) 是不可逆的、高效的、选择性的线粒体单胺氧化酶 (MAO) 抑制剂，抑制大鼠脑 MAO B 和 MAO A 的 IC50分别为 4.43 nM 和 412 nM。
T9585	GNE-9815 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide	Raf	MAPK
	GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) 是一种高激酶选择性 RAF 抑制剂，可用于通过联合治疗靶向 KRAS 突变癌症。
T60009	YS-370	P-gp	Membrane transporter/Ion channel; Neuroscience
	YS-370 是一种具有口服活性的 P-gp 抑制剂，对 CYP3A4 有中度抑制作用。 YS-370 有效逆转对紫杉醇和秋水仙碱的多药耐药性，与紫杉醇联合应用表现出更强的抗肿瘤活性。
T40598	Norethindrone acetate 19-Norethindroneacetate	Estrogen Receptor/ERR; Progesterone Receptor	Endocrinology/Hormones; Others
	Norethindrone acetate (19-Norethindroneacetate) 是一种雌性激素，对青少年月经和肝腺瘤有抑制作用，常与孕激素联合使用，可用于研究子宫内膜异位症。
T2204	Diaveridine 二氨藜芦啶,EGIS-5645,敌菌净,CCRIS-3784,AI3-23935	DHFR; Antifolate; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Diaveridine (AI3-23935) 是二氢叶酸还原酶的抑制剂，对于野生型 DHFR 的Ki 值为 11.5 nM。它也是一种抗菌剂。
T19080	DOPE 1,2-二油酰-SN-甘油-3-磷酰乙醇胺	Others	Others
	DOPE (DOPE) 是一种阳离子脂质体的中性辅助脂质 (helper lipid)，能够与阳离子磷脂结合，增强裸 siRNA 的转染效率。
T0100	Atazanavir sulfate 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir sulfate (BMS-232632 sulfate) 是一种氮杂肽和 HIV 蛋白酶抑制剂，与其他抗 HIV 药物联合用于治疗 HIV 感染和艾滋病。它也是SARS-CoV 3CLpro 抑制剂，IC50为 3.49 μM。
T21432	Molindone (±)-Molindone,Moban,Molindonum,SPN-810M	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Molindone ((±)-Molindone) 是一种治疗性抗精神病药物，通过阻断大脑中多巴胺的作用而用于治疗精神分裂症。Molindone 常与羟色胺联合使用，以剂量依赖性方式增加错误并降低反应率。
T15673	KU 59403 KU-59403,KU59403	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	KU 59403 是一种具有选择性和高效性的 ATM 抑制剂，具有抗肿瘤和抗癌活性，抑制 ATM、DNA-PK 和 PI3K，常与PARP或ATR抑制剂的联合治疗来延缓癌症的进程。
T77440	Codrituzumab RG-7686,RO5137382,GC33
	Codrituzumab (GC3）是一种人源化针对 glypican-3 肝癌蛋白的抗体，可与索拉非尼联合使用来研究不可治愈的晚期肝细胞癌 (HCC）。
T8856	Ascorbyl Propyl Hyaluronate	Others	Others
	Ascorbyl Propyl Hyaluronate 是透明质酸和维生素 C 的完美结合，克服了维生素 C 的不稳定性，是改善皱纹、滋润、镇静肌肤、美白的优质原料。
T7318	Elimusertib BAY-1895344	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Elimusertib (BAY-1895344) 是一种可口服的选择性ATR 抑制剂，IC50值为 7 nM。它具有抗肿瘤活性，可研究实体瘤和淋巴瘤。
T3658	Trifluridine/tipiracil hydrochloride mixture Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Trifluridine/tipiracil hydrochloride mixture (TAS-102) 是一种新型口服组合药物，含有摩尔比为 2:1 的曲氟尿苷(TFT) 和盐酸替吡嘧啶 (TTP)。它主要通过抑制胸苷酸合酶 (TS) 和掺入 DNA 来显示抗肿瘤活性。
T3335	Darunavir Ethanolate 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Darunavir Ethanolate (UIC 94017) 是一种HIV 蛋白酶抑制剂，可以用于 HIV/AIDS 的相关研究。对野生型 HIV-1 蛋白酶的Ki 值为1 nM。
T8875	CD73-IN-3 EX-A4254,LY-3475070	CD73	Immunology/Inflammation
	CD73-IN-3 (LY-3475070) 是一种有效的选择性 CD73 抑制剂，IC50 为 28 nM，具有癌症的研究潜力。
T9718	Ethoxylated hydrogenated castor oil	Others	Others
	Ethoxylated hydrogenated castor oil 是一种聚乙二醇与天然蓖麻油的混合物，可用于水包油 (o/w) 乳浊液的乳化和增溶，是动物实验的良好助溶剂。
T9277	ALC-0315	Others	Others
	ALC-0315是一种可电离的氨基脂质，已与其他脂质组合用于形成脂质纳米颗粒。脂质纳米颗粒已经用于 mRNA (COVID-19) 疫苗的研究。
T1595	Nevirapine NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Nevirapine (NVP) 是一种 HIV-1逆转录酶非核苷抑制剂，Ki 值为 270 μM，可用于研究 HIV/AIDS。
T35394	Sintilimab (anti-PD-1) IBI308,Sintilimab (anti-PD-1)	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Sintilimab (IBI308) 是一种人源化的 IgG4 单克隆抗体，具有显著的抗肿瘤活性，通过与 PD-1 结合从而阻断 PD-1 与其配体 (PD-L1 和 PL-L2) 的相互作用，进而恢复内源性抗肿瘤 T 细胞反应。Sintilimab 联合其他化合物来治疗经典霍奇金淋巴瘤、非小细胞肺癌和食管癌。
T77466	Tremelimumab Ticilimumab,CP-675206	Others	Others
	Tremelimumab 是一种细胞毒性T淋巴细胞相关抗原-4（CTLA-4）阻断抗体.Tremelimumab 常与 Durvalumab 联合使用来治疗肝癌、肺癌等实体癌。
T0930	Sulfadiazine Sulphadiazine,磺胺嘧啶	Antibacterial; Antibiotic; Parasite; Autophagy	Autophagy; Microbiology/Virology
	Sulfadiazine (Sulphadiazine) 是一种磺胺类抗生素具有抗疟活性，可研究弓形虫病。
T4563	Thonzylamine neohetramine,松齐拉敏	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂，具有抗组胺和抗过敏特性，可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。
T76788	Demcizumab OMP 21M18	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Demcizumab (OMP 21M18) 是一种抗 DLL4 单克隆抗体。Demcizumab 是一种有效的 Notch 通路抑制剂。Demcizumab 在多种癌症模型中无论使单独还联合化疗试剂使用都是有效的。
T4100	AS8351 NSC51355,AS-8351,AS 8351	Histone Demethylase	Chromatin/Epigenetic
	AS8351 (NSC51355) 是一种组蛋白去甲基化酶抑制剂，可以诱导人胎儿肺成纤维细胞重编程为功能性心肌细胞。

化合物

Ascorbic acid, rutoside drug combination

Cat.No: T23757

Synonym: Rutinoscorbin,Rutascorbin,Ruta C 60,Cerutin

Target: Others

Cat.No: T12829

Synonym: 沙美特罗,GR33343X

Target: Adrenergic Receptor

Cat.No: T7614

Synonym: GW776C85,5-Ethynyluracil

Target: Others

Cat.No: T3661

Synonym: ACY241,HDAC-IN-2

Target: HDAC

Piperaquine tetraphosphate tetrahydrate

Cat.No: T7744

Synonym: 4,4'-(1,3-丙烷双-4,1-哌嗪基)双(7-氯喹啉)磷酸盐水合物,四磷酸哌喹四水合物

Target: Parasite

Salmeterol Xinafoate

Cat.No: T6653

Synonym: Salmetedur,昔美酸沙美特罗,沙美特罗昔萘酸酯,GR 33343X xinafoate,Arial

Target: HIV Protease, Adrenergic Receptor

Cat.No: T7532

Target: Parasite

Cat.No: T31088

Synonym: Cytarabine/daunonubicin,Vyxeos,CPX 351,Daunonubicin/cytarabine

Target: Others

Cat.No: T3266

Synonym: Benflumetol,dl-Benflumelol,苯芴醇

Target: Others, Parasite, Autophagy

Cat.No: T2554

Target: Others

Cat.No: T1430

Synonym: CS-443,N-Benzoyl-β-alanine,倍他米隆

Target: Antibacterial, Antibiotic

Cat.No: T2239L

Synonym: 雷特格韦,MK-0518

Target: HIV Protease, Integrase

(S, R)-LSN 3318839

Cat.No: T63166L

Synonym: (S, R)-LSN 3318839(Isomer-2764704-18-7)

Target: Glucagon Receptor

Cat.No: T7537

Synonym: 炔诺肟酯,诺孕酯

Target: Progesterone Receptor

L-797,591 hydrochloride

Cat.No: T27787L

Synonym: L-797,591 hydrochloride(217480-24-5 Free base)

Target: Others

Azido-PEG1-CH2CO2H

Cat.No: T14408

Synonym: 4-哌啶酮缩乙二醇

Target: Others, PROTAC Linker

Cat.No: T65232

Synonym: N-(2-Hydroxyethyl)ethylenediaminetriacetic acid

Target: Others

Cat.No: T7045

Synonym: Nexiclon,Catapres,Kapvay,可乐定

Target: Adrenergic Receptor

Cat.No: T30686

Synonym: l-Cafedrine,Cafedrin

Target: Others

Sultamicillin Tosylate

Cat.No: T3139

Synonym: Bacimex,舒巴西林,舒他西林甲苯磺酸盐,Unacim orale

Target: Antibacterial, Antibiotic

Folinic Acid Calcium Salt Pentahydrate

Cat.No: T0148L

Synonym: Folinic acid,亚叶酸钙五水合物,Leucovorin Calcium Pentahydrate,Leucovorin calcium salt pentahydrate

Target: Others, Antifolate

Cat.No: T35354

Target: Others

(S)-Mirtazapine

Cat.No: T12632L

Synonym: (S)-6-Azamianserin,(S)-Org3770

Target: 5-HT Receptor

Cat.No: T67964

Target: Microtubule Associated

Ethynodiol diacetate

Cat.No: T0996

Synonym: Ethynodiol acetate,双醋炔诺醇,8080 CB

Target: Estrogen/progestogen Receptor, Progesterone Receptor

Cat.No: T76877

Synonym: RG-7444,B-701,MFGR-1877S

Target: FGFR

Cat.No: T1119

Synonym: 雷沙吉兰,AGN1135,TVP1012

Target: BCL, MAO, Monoamine Oxidase

Cat.No: T9585

Synonym: 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide

Target: Raf

Cat.No: T60009

Target: P-gp

Norethindrone acetate

Cat.No: T40598

Synonym: 19-Norethindroneacetate

Target: Estrogen Receptor/ERR, Progesterone Receptor

Cat.No: T2204

Synonym: 二氨藜芦啶,EGIS-5645,敌菌净,CCRIS-3784,AI3-23935

Target: DHFR, Antifolate, Antibacterial

Cat.No: T19080

Synonym: 1,2-二油酰-SN-甘油-3-磷酰乙醇胺

Target: Others

Atazanavir sulfate

Cat.No: T0100

Synonym: 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦

Target: P450, SARS-CoV, HIV Protease, P-gp

Cat.No: T21432

Synonym: (±)-Molindone,Moban,Molindonum,SPN-810M

Target: Dopamine Receptor

Cat.No: T15673

Synonym: KU-59403,KU59403

Target: ATM/ATR

Cat.No: T77440

Synonym: RG-7686,RO5137382,GC33

Ascorbyl Propyl Hyaluronate

Cat.No: T8856

Target: Others

Cat.No: T7318

Synonym: BAY-1895344

Target: ATM/ATR

Trifluridine/tipiracil hydrochloride mixture

Cat.No: T3658

Synonym: Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Darunavir Ethanolate

Cat.No: T3335

Synonym: 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇

Target: HIV Protease

Cat.No: T8875

Synonym: EX-A4254,LY-3475070

Target: CD73

Ethoxylated hydrogenated castor oil

Cat.No: T9718

Target: Others

Cat.No: T9277

Target: Others

Cat.No: T1595

Synonym: NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP

Target: HIV Protease, Reverse Transcriptase

Sintilimab (anti-PD-1)

Cat.No: T35394

Synonym: IBI308,Sintilimab (anti-PD-1)

Target: PD-1/PD-L1

Cat.No: T77466

Synonym: Ticilimumab,CP-675206

Target: Others

Cat.No: T0930

Synonym: Sulphadiazine,磺胺嘧啶

Target: Antibacterial, Antibiotic, Parasite, Autophagy

Cat.No: T4563

Synonym: neohetramine,松齐拉敏

Target: Histamine Receptor

Cat.No: T76788

Synonym: OMP 21M18

Target: Gamma-secretase

Cat.No: T4100

Synonym: NSC51355,AS-8351,AS 8351

Target: Histone Demethylase

Cat. No.	Product Name	Target	Signaling Pathways
TN2943	3-Hydroxy-6-methoxyflavone	Others	Others
	3-Hydroxy-6-methoxyflavone 可与抗生素联合用药来治疗 ESKAPE 病原体感染。
TJS0339	Coumarin-3-carboxylic acid 香豆素-3-羧酸,3-Carboxycoumarin	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Coumarin-3-carboxylic acid (3-Carboxycoumarin) 是一种合成香豆素的重要起始化合物。其中香豆素是具有多种生物活性的天然产物。它的镧系复合物对 K-562 细胞具有抗增殖活性。
T24403	Folinic acid HSDB 6544,Leucovorin	Endogenous Metabolite; Antifolate	Cell Cycle/Checkpoint; Metabolism
	Folinic acid (Leucovorin) 是一种可用于治疗甲氨蝶呤的生物叶酸，通常与 Methotrexate (MTX) 联用来降低 MTX 诱导的毒性，可用于辅助治疗结肠癌。
TN1877	Lonicerin 忍冬苦苷,金银花	Apoptosis; Antibacterial	Apoptosis; Microbiology/Virology
	Lonicerin 是一种抗藻酸盐分泌蛋白的黄酮类化合物，对铜绿假单胞菌有抑制作用。它可预防脂多糖诱导的急性肺损伤的炎症和细胞凋亡。
T0004	Salicylamide 水杨酰胺,Salamide,2-Hydroxybenzamide	COX	Immunology/Inflammation; Neuroscience
	Salicylamide(2-Hydroxybenzamide) 是一种止痛剂和抗热解药剂，是一种微粒体 UDP-葡糖醛酸基转移酶抑制剂。
T1589	D-Cycloserine RO-1-9213,D-环丝氨酸	Others; Antibacterial; Antibiotic; iGluR	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
	D-Cycloserine (RO-1-9213) 是一种抗生素，靶向细菌细胞壁肽聚糖生物合成酶。它是一种NMDA 部分激动剂，可以改善认知功能，可研究耐多药结核病。
T4S0094	Hydroxygenkwanin 羟基芫花素,Luteolin 7-methylether,7-O-Methylluteolin	Antioxidant	oxidation-reduction
	Hydroxygenkwanin (Luteolin 7-methylether) 是一种丁香达芙妮的主要成分，是一种天然的类黄酮化合物。它具有抗氧化，抗神经胶质瘤能力和抗癌作用。
T3733	(E)-Methyl 4-coumarate Methyl trans-p-Coumarat,OMpCA,反式对羟基肉桂酸,Methyl 4-hydroxycinnamate	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Methyl (E)-4-hydroxycinnamatee在几种植物中发现，如洋葱或海巴戟叶中。它与 Carnosic Acid 联用可诱导细胞凋亡，杀死急性髓性白血病细胞。它具有抗氧化和抗菌活性。
T4915	β-Glycerophosphate disodium salt hydrate	Phosphatase; Endogenous Metabolite	Metabolism
	β-Glycerophosphate disodium salt hydrate 是一种磷酸酶抑制剂，是内源性代谢产物的一种。
T6S1683	Demethoxycurcumin Curcumin II,去甲氧基姜黄素,Desmethoxycurcumin,脱甲氧姜黄,Monodemethoxycurcumin	Apoptosis; Antioxidant; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; oxidation-reduction
	Demethoxycurcumin (Desmethoxycurcumin) 是姜黄素的主要活性成分，有抗炎和抗癌作用。
T3S0364	L-Arginine L-精氨酸,L-Arg,(S)-(+)-Arginine	IL Receptor; Endogenous Metabolite; NO Synthase	Immunology/Inflammation; Metabolism
	L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞，并被代谢成一氧化氮、多胺或 L-脯氨酸。
TN1362	Afzelin 阿福豆苷,Kaempferol-3-O-rhamnoside	PTEN; p38 MAPK; TNF; Mitochondrial Metabolism; Antibacterial; Prostaglandin Receptor; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Afzelin (Kaempferol-3-O-rhamnoside) 具有多种细胞活性，例如 DNA 保护、抗菌、抗氧化和抗炎以及 UV 吸收活性，并且可以通过 UV 吸收和细胞活性的组合保护人体皮肤免受 UVB 引起的损伤。 Afzelin 减轻线粒体损伤，增强线粒体生物合成并降低线粒体自噬相关蛋白、parkin 和 putative kinase 1 的水平。
T5074	Cholesteryl palmitate	Others; Endogenous Metabolite	Metabolism; Others
	Cholesteryl palmitate 是一种慢性间质性肺炎的有用预后生物标志物。
T5S0053	Coptisine 黄连碱,Coptisin	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Coptisine (Coptisin) 是一种从黄连中分离到的生物碱，是非竞争性的IDO 抑制剂，Ki=为 5.8 μM，IC50=6.3 μM。
T2S1865	Octyl gallate Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯	Antioxidant; Influenza Virus; Reactive Oxygen Species; Antibacterial; Antifungal; HSV	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction
	Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用，有选择性和敏感性的荧光特性，广泛用作食品添加剂。它对 HSV-1，水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。
T4S1551	Cinnamaldehyde Cinnamic Aldehyde,肉桂醛	HIF	Angiogenesis; Chromatin/Epigenetic
	Cinnamaldehyde (Cinnamic Aldehyde) 具有解热作用。它是镇静剂。它抑制MDA-MB-435S 细胞的侵袭能力与下调miR-27a 的表达有关。它诱导活性氧的产生，发挥血管扩张和抗癌作用。它似乎是一种有希望的候选药物，可作为与 5-氟尿嘧啶 (5-FU) 和奥沙利铂 (OXA) 这两种用于 CRC 治疗的化疗药物联合治疗的辅助剂。其作用的可能机制可能涉及药物代谢基因的调节。它在抑制黑色素瘤的发生和发展方面具有一定的作用，其作用机制可能表现为抑制VEGF 和HIF-α的表达，从而使血管模拟和黑色素瘤细胞新生血管的形成，促进肿瘤的生长。
TN2524	1-Acetyl-β-carboline 1-Acetyl-beta-carboline	Antifection	Microbiology/Virology
	Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.
T11895	Luteolin-7-rutinoside	Others	Others
	Luteolin-7-rutinoside has both antifungal activities and anti-arthritic, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
TN1349	9-Hydroxycalabaxanthone	Antifection	Microbiology/Virology
	9-Hydroxycalabaxanthone exhibits cytotoxicity against the HT-29 cell line with ED50 values of 9.1 microM. The combination of 9-hydroxycalabaxanthone with α±-mangostin shows the synergistic antimalarial interaction in both clones.
TN5466	Boeravinone B
	Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for further development. Boeravinone B exh
T40859	5-Hydroxy-8-methoxypsoralen 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen	Others	Others
	5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite derived from Xanthotoxin, which acts as a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). It is employed as an agent for the treatment of psoriasis, eczema, vitiligo, and certain cutaneous Lymphomas, in combination with phototherapy involving exposure to sunlight.
TMA1008	Ganoderic acid S	Others	Others
	A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon ca
TN1498	Cimigenol	Others	Others
	Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87μM) and A-549 (12.16 μM
T37751	Streptazolin	Others	Others
	Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes. It increases NF-κB activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling. Streptazolin enhances TNF-α secretion induced by LPS and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells.
T14047	5-Aminolevulinic acid 5-Amino-4-oxopentanoic acid	Others	Others
	5-Aminolevulinic acid 是血红素合成的中间体，是卟啉合成途径中的一个化合物。它是一种光敏剂、抗肿瘤剂和前药。它也可以(以盐酸盐的形式)与蓝光照明结合使用，用于治疗面部或头皮的轻度至中度厚的光化性角化病。
T36886	Pestalotin	Others	Others
	Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from 3 to 100 mg/L and enhances growth of rice seedlings (O. sativa) when used in combination with gibberellin A3 at concentrations ranging from 30 to 500 mg/L. Pestalotin has antifungal activity, reducing the growth of C. albicans, C. neoformans, T. rubrum, and A. fumigatus (MICs = 1...
TN3708	Coronarin D	BCL; c-Myc; TNF; NF-κB; Caspase; COX; Antifection	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
	Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, i
T36417	Nargenicin Antibiotic 47444	Others	Others
	Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (...
TN7560	PF-1163A	Others	Others
	PF-1163A, a depsipeptide antifungal compound isolated from Penicillium, blocks ergosterol synthesis with an IC50 of 12 ng/ml. This compound specifically inhibits the enzyme ERG25p, a C-4 methyl oxidase in the ergosterol biosynthetic pathway, leading to its antifungal activity. Notably, in Saccharomyces cerevisiae modified to express ERG biosynthesis genes, PF-1163A exhibits an inhibition concentration (MIC value) of 12.5 µg/ml against ERG25p, though strains overexpressing ERG25p show resistance....
TN4291	Isofuranodiene	IL Receptor; NOS	Immunology/Inflammation
	Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apo

天然产物

3-Hydroxy-6-methoxyflavone

Cat.No: TN2943

Target: Others

Coumarin-3-carboxylic acid

Cat.No: TJS0339

Synonym: 香豆素-3-羧酸,3-Carboxycoumarin

Target: VEGFR

Cat.No: T24403

Synonym: HSDB 6544,Leucovorin

Target: Endogenous Metabolite, Antifolate

Cat.No: TN1877

Synonym: 忍冬苦苷,金银花

Target: Apoptosis, Antibacterial

Cat.No: T0004

Synonym: 水杨酰胺,Salamide,2-Hydroxybenzamide

Target: COX

Cat.No: T1589

Synonym: RO-1-9213,D-环丝氨酸

Target: Others, Antibacterial, Antibiotic, iGluR

Hydroxygenkwanin

Cat.No: T4S0094

Synonym: 羟基芫花素,Luteolin 7-methylether,7-O-Methylluteolin

Target: Antioxidant

(E)-Methyl 4-coumarate

Cat.No: T3733

Synonym: Methyl trans-p-Coumarat,OMpCA,反式对羟基肉桂酸,Methyl 4-hydroxycinnamate

Target: Apoptosis, Others, Antibacterial

β-Glycerophosphate disodium salt hydrate

Cat.No: T4915

Target: Phosphatase, Endogenous Metabolite

Demethoxycurcumin

Cat.No: T6S1683

Synonym: Curcumin II,去甲氧基姜黄素,Desmethoxycurcumin,脱甲氧姜黄,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

Cat.No: T3S0364

Synonym: L-精氨酸,L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

Cat.No: TN1362

Synonym: 阿福豆苷,Kaempferol-3-O-rhamnoside

Target: PTEN, p38 MAPK, TNF, Mitochondrial Metabolism, Antibacterial, Prostaglandin Receptor, Autophagy

Cholesteryl palmitate

Cat.No: T5074

Target: Others, Endogenous Metabolite

Cat.No: T5S0053

Synonym: 黄连碱,Coptisin

Target: Indoleamine 2,3-Dioxygenase (IDO)

Cat.No: T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

Cat.No: T4S1551

Synonym: Cinnamic Aldehyde,肉桂醛

Target: HIF

1-Acetyl-β-carboline

Cat.No: TN2524

Synonym: 1-Acetyl-beta-carboline

Target: Antifection

Luteolin-7-rutinoside

Cat.No: T11895

Target: Others

9-Hydroxycalabaxanthone

Cat.No: TN1349

Target: Antifection

Cat.No: TN5466

5-Hydroxy-8-methoxypsoralen

Cat.No: T40859

Synonym: 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen

Target: Others

Ganoderic acid S

Cat.No: TMA1008

Target: Others

Cat.No: TN1498

Target: Others

Cat.No: T37751

Target: Others

5-Aminolevulinic acid

Cat.No: T14047

Synonym: 5-Amino-4-oxopentanoic acid

Target: Others

Cat.No: T36886

Target: Others

Cat.No: TN3708

Target: BCL, c-Myc, TNF, NF-κB, Caspase, COX, Antifection

Cat.No: T36417

Synonym: Antibiotic 47444

Target: Others

Cat.No: TN7560

Target: Others

Cat.No: TN4291

Target: IL Receptor, NOS

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00528	Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His) UVSX,Recombination and repair protein	Enterobacteria phage T4	E. coli
	Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.
TMPY-02646	NSE/ENO2 Protein, Human, Recombinant (His) enolase 2 (γ, neuronal),NSE,HEL-S-279,enolase 2 (gamma, neur...	Human	E. coli
	The combination of silencing ENO2 and 2-deoxyglucose (2-DG) synergistically inhibited leukemia cell survival. ENO2 may be a biological marker for monitoring chemotherapeutic efficacy and relapse in ALL. Reduced ENO2 expression may be a biomarker for a subset of autistic children. Neuron specific enolase (ENO2, gamma-enolase) has been used as a biomarker to help identify neuroendocrine differentiation in breast cancer.
TMPY-03962	AFM Protein, Human, Recombinant (His) afamin,ALBA,ALB2,ALF	Human	HEK293 Cells
	Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of...
TMPH-01435	Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc) Hemoglobin gamma-1 chain,Hemoglobin subunit gamma-1,Gamma-1-...	Human	E. coli
	Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.0 kDa and the accession number is P69891.
TMPK-00893	PGF Protein, Human, Recombinant (hFc) PlGF,SHGC-10760,PGFL,PGF,D12S1900,PlGF-2	Human	HEK293 Cells
	Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV possibly via modulating their own expression in mononuclear phagocytes. PGF-related, optimized strategies to target inflammation-mediated angiogenesis may help to increase efficacy and reduce non-responders in the treatment of wet AMD patients.
TMPJ-00895	SCF Protein, Rat, Recombinant (HEK293, His) steel factor,Mast cell growth factor,SLF,MGFSHEP7,SCFStem ce...	Rat	HEK293 Cells
	SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II...
TMPY-00151	Alpha SNAP Protein, Human, Recombinant (His) N-ethylmaleimide-sensitive factor attachment protein, alpha,...	Human	E. coli
	NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of s...
TMPJ-00070	IL-18 Protein, Human, Recombinant (His) GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-18,Interferon γ-ind...	Human	HEK293 Cells
	Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After...
TMPY-01865	BLMH Protein, Mouse, Recombinant (His) Bh,bleomycin hydrolase,Bmh,AI035728	Mouse	E. coli
	The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide antica...
TMPY-03861	Amelotin Protein, Human, Recombinant (mFc) amelotin,UNQ689	Human	HEK293 Cells
	Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface which protects against the constant microbiological challenge to the periodontium. TNF-α stimulates AMTN gene transcription in human gingival epithelial cells via C/EBP1, C/EBP2, and YY1 elements in the human AMTN gene promoter.AMTN mRNA levels increased at 6 h and reached maximum a...
TMPY-02766	PSPH Protein, Human, Recombinant PSP,phosphoserine phosphatase,PSPHD	Human	E. coli
	Phosphoserine phosphatase (PSPH) belongs to a subfamily of the phosphotransferases. PSPH is the rate-limiting enzyme in l-serine biosynthesis. It has previously been found that Phosphoserine phosphatase (PSPH) plays a role in epidermal homeostasis. Phosphoserine phosphatase (PSP) catalyzes the hydrolysis of phosphoserine to serine. Phosphoserine phosphatase (PSPH) expression has been examined in human-mouse somatic cell hybrids retaining different combination of human chromosomes. Phosphoserine ...
TMPY-00564	MCP-4 Protein, Human, Recombinant (His) MCP-4,CCL13,SCYL1,NCC-1,MCP4,NCC1,CKb10,SCYA13,chemokine (C-...	Human	P. pastoris (Yeast)
	Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chem...
TMPY-01416	OLFM4 Protein, Human, Recombinant (His) hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomedin 4,OlfD,hOLfD,UN...	Human	HEK293 Cells
	Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed...

重组蛋白

Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His)

Cat.No: TMPH-00528

Species: Enterobacteria phage T4

Expression System: E. coli

NSE/ENO2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02646

Species: Human

Expression System: E. coli

AFM Protein, Human, Recombinant (His)

Cat.No: TMPY-03962

Species: Human

Expression System: HEK293 Cells

Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01435

Species: Human

Expression System: E. coli

PGF Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00893

Species: Human

Expression System: HEK293 Cells

SCF Protein, Rat, Recombinant (HEK293, His)

Cat.No: TMPJ-00895

Species: Rat

Expression System: HEK293 Cells

Alpha SNAP Protein, Human, Recombinant (His)

Cat.No: TMPY-00151

Species: Human

Expression System: E. coli

IL-18 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00070

Species: Human

Expression System: HEK293 Cells

BLMH Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01865

Species: Mouse

Expression System: E. coli

Amelotin Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03861

Species: Human

Expression System: HEK293 Cells

PSPH Protein, Human, Recombinant

Cat.No: TMPY-02766

Species: Human

Expression System: E. coli

MCP-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00564

Species: Human

Expression System: P. pastoris (Yeast)

OLFM4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01416

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T31813	Fludalanine MK641,D-Alanine-2-d, 3-fluoro-,3-Fluoro-D-(2-2H)alanine
	Fludalanine (MK641), an analogue of D-alanine, irreversiably inactivates racemase and also inhibits synthase. When used in combination with cycloserine, it has been found to be more active against a variety of non-mycobacterium organisms than fludalanine
TMIJ-0072	Lumefantrine-d9
	Lumefantrine-d9 是 Lumefantrine 的氘代化合物。Lumefantrine 的 CAS 号为 82186-77-4。Lumefantrine是一种抗疟药，用于治疗急性单纯性疟疾。与Artemether联用，可提高疗效。
TMID-0205	Nevirapine-d4
	Nevirapine-d4 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMIJ-0039	Norethindrone Acetate-2,2,4,6,6,10-d6
	Norethindrone Acetate-2,2,4,6,6,10-d6 是 Norethindrone Acetate 的氘代化合物。Norethindrone Acetate 的 CAS 号为 51-98-9。Norethindrone acetate 是一种雌性激素，对青少年月经和肝腺瘤有抑制作用，常与孕激素联合使用，可用于研究子宫内膜异位症。
TMIJ-0239	Cobicistat-d8
	Cobicistat-d8 是 Cobicistat 的氘代化合物。Cobicistat 的 CAS 号为 1004316-88-4。Cobicistat 是一种细胞色素酶P450 3A 的选择性抑制剂，IC50值为30-285 nM。它是一种药代动力学增强剂，可增强抗 HIV 药物的吸收。
TMID-0206	Nevirapine-d3
	Nevirapine-d3 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMID-0126	Clonidine-d4 Hydrochloride
	Clonidine-d4 Hydrochloride 是 Clonidine Hydrochloride 的氘代化合物。Clonidine Hydrochloride 的 CAS 号为 4205-91-8。Clonidine hydrochloride 是一种α2-adrenoceptor激动剂，是一种抗高血压药。
TMIH-0181	Demethoxy Curcumin-d4
	Demethoxy Curcumin-d4 是 Demethoxy Curcumin 的氘代化合物。Demethoxy Curcumin 的 CAS 号为 22608-11-3。Demethoxycurcumin是姜黄素的主要活性成分，有抗炎和抗癌作用。
TMID-0188	Mianserin-d3
	Mianserin-d3 是 Mianserin 的氘代化合物。Mianserin 的 CAS 号为 24219-97-4。Mianserin是H1受体反向激动剂，是四环抗抑郁药(TeCA)治疗家族中的一种精神活性化合物，具有抗抑郁、抗焦虑、止吐、促氧、催眠和抗组胺作用，可作为去甲肾上腺素和特定的血清素联合用药能治疗抑郁症。
TMIJ-0252	Benazeprilat-d5 Benazepril EP Impurity C-d5
	Benazeprilat-d5 是 Benazeprilat 的氘代化合物。Benazeprilat 的 CAS 号为 86541-78-8。Benazeprilat(CGS 14831) 是一种具有口服活性的贝那普利活性代谢物。Benazeprilat 具有高效的抗血压活性，可与其他其他类别的化合物（包括噻嗪类利尿剂和钙通道阻滞剂）联合使用来减少与心血管风险和继发性终末器官损伤相关的疾病的发生。Benazeprilat 可能用于研究急性左心室衰竭。

同位素标记化合物

Cat.No: T31813

Synonym: MK641,D-Alanine-2-d, 3-fluoro-,3-Fluoro-D-(2-2H)alanine

Lumefantrine-d9

Cat.No: TMIJ-0072

Cat.No: TMID-0205

Norethindrone Acetate-2,2,4,6,6,10-d6

Cat.No: TMIJ-0039

Cat.No: TMIJ-0239

Cat.No: TMID-0206

Clonidine-d4 Hydrochloride

Cat.No: TMID-0126

Demethoxy Curcumin-d4

Cat.No: TMIH-0181

Cat.No: TMID-0188

Benazeprilat-d5

Cat.No: TMIJ-0252

Synonym: Benazepril EP Impurity C-d5

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