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Targets Recommended: Others

176

抑制剂 & 化合物

48

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6

化合物库

3

TargetMol 试剂盒

424

重组蛋白

10

同位素标记化合物

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Cat. No. Product Name
L4100 TGF-β/Smad靶点化合物库

184 compounds
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选;
L8000 干细胞分化化合物库

1197 compounds
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;
L4010 已知活性化合物库

22555 compounds
22555 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认;
L6710 中药抗炎分子库

1246 compounds
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具;
L4700 免疫/炎症分子化合物库

4720 compounds
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选;
L6610 抗感染天然产物库

1060 compounds
1060 个抗感染相关的天然产物集合,是药物开发、药理研究的有效工具;

化合物库

TGF-β/Smad靶点化合物库
Cat.No: L4100
Compounds: 184
干细胞分化化合物库
Cat.No: L8000
Compounds: 1197
已知活性化合物库
Cat.No: L4010
Compounds: 22555
中药抗炎分子库
Cat.No: L6710
Compounds: 1246
免疫/炎症分子化合物库
Cat.No: L4700
Compounds: 4720
抗感染天然产物库
Cat.No: L6610
Compounds: 1060
Cat. No. Product Name Form Specificity Of Inhibition
C0045 RIPA Lysis Buffer (Strong)

RIPA裂解液(强)

Solution in bottle
C0046 RIPA Lysis Buffer (Medium)

RIPA裂解液(中)

Solution in bottle
C0047 RIPA Lysis Buffer (Weak)

RIPA裂解液(弱)

Solution in bottle

TargetMol 试剂盒

RIPA裂解液(强)
Cat.No: C0045
RIPA裂解液(中)
Cat.No: C0046
RIPA裂解液(弱)
Cat.No: C0047
Cat. No. Product Name Target Signaling Pathways
TP1286 Carcinoembryonic Antigen CEA

癌胚抗原

Others Others
Carcinoembryonic Antigen CEA 是一种广谱性肿瘤标志物,是大肠癌组织产生的一种糖蛋白,作为抗原可引起患者的免疫反应。
T0907 Sulfasalazine

柳氮磺吡啶,NSC 667219,Azulfidine

Apoptosis; Ferroptosis; NF-κB; COX; Antibacterial; Antibiotic; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
Sulfasalazine (Azulfidine) 是一种合成的水杨酸衍生物,对含有弹性蛋白的结缔组织具有亲和力,并配制成前药。
TP2492 Hexapeptide-9 Acetate

Hexapeptide-9 Acetate(1228371-11-6 Free base)

Others Others
Hexapeptide-9 Acetate 是一种胶原蛋白肽,通过与皮肤细胞自然相互作用来帮助强化结构组织,从而促进再生过程。
T0380 Bicalutamide

比卡鲁胺,ICI-176334

Androgen Receptor; Autophagy Autophagy; Endocrinology/Hormones
Bicalutamide (ICI-176334) 是一种具有口服活性的非甾体雄激素受体拮抗剂,可研究前列腺癌。
T9608 KL201

Others Others
KL201 是一种昼夜节律调制器,是 CRY1选择性的 稳定剂, 对 CRY2 没有稳定作用。KL201 延长了细胞和组织中的昼夜节律周期。
TQ0133 Amifostine thiol dihydrochloride

WR 1065,硫代乙基氨基乙基胺盐酸盐

p53 Apoptosis
Amifostine thiol dihydrochloride (WR 1065) 可通过 JNK 依赖性信号通路激活 p53。它还可以保护正常组织免受某些抗癌药物的毒性作用。
T2121 SW033291

Dehydrogenase Metabolism
SW033291 是有效的15-PGDH 抑制剂,与15-PGDH 亲和力高,Ki 为 0.1 nM。它增加骨髓和其他组织中前列腺素 PGE2 的水平。它还可促进组织再生。
T25867 Nicodan Percutan

Nicotinic acid, propyl ester,Propylnicotinat,烟酸丙酯,Propyl pyridine-3-carboxylate,n-Propyl nicotinate,NSC-78447,NSC 78447,NSC78447

Others Others
Nicodan Percutan (Propylnicotinat) 是烟酸的丙酯形式,烟酸在各种动物和植物组织中存在,用于形成辅酶NAD 和NADP。
T9053 Lats-IN-1

Others; YAP Others; Stem Cells
Lats-IN-1 是一种 ATP 竞争性的、高效的Lats1和Lats2激酶抑制剂,能促进有丝分裂后哺乳动物组织的 Yap 依赖性增殖。
T0668 1-Aminohydantoin hydrochloride

Others Others
1-Aminohydantoin hydrochloride 是一种呋喃妥因在动物组织中的主要代谢物。它与组织蛋白共价结合,在微酸性条件下从组织中释放出来,与 2-硝基苯甲醛衍生形成 AHD 的硝基苯基衍生物可被检测。它可作为测定肉、奶等兽药残留的测定指标。
T14981 Clobetasone butyrate

Glucocorticoid Receptor Endocrinology/Hormones
Clobetasone butyrate 是糖皮质类固醇,特别是在皮肤上,具有局部抗炎活性。它可用于改善皮质类固醇反应性症状,如特应性皮炎、牛皮癣。
T4506 Gadopentetate dimeglumine

Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt

Others Others
Gadopentetate dimeglumine 可用于核磁共振成像 (MRI) 中,使血管、器官和其他非骨组织能够更清晰地被看到。Gadopentetate dimeglumine 可诱导生精细胞萎缩。
T19057 Solvent Blue 35

Sudan Blue II,溶剂蓝35,溶剂蓝 35,Oil Blue 35

Others Others
Solvent Blue 35 (Sudan Blue II) 是一种可用于着色醇类和烃基溶剂的染料。它能够作用于染色动物组织中的甘油三酯。
T20913 Light Green SF Yellowish

Acid Green 5,C.I. Acid Green 5,C.I. 42095

Light Green SF Yellowish (Acid Green 5) 是一种碱性染色剂,可用于动物组织染色,可用于植物组织学中作细胞质和纤维染色。
T68122 Oxmetidine

SKF 92994,Oxmetidina,Oxmetidinum

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Oxmetidine (SKF 92994) 是一种新型 H2 受体拮抗剂,具有细胞毒性。 Oxmetidine 抑制心脏和血管组织中跨膜钙通量,可用于治疗活动性十二指肠溃疡。
TD0105 Sulfobromophthalein disodium salt

Others Others
Sulfobromophthalein disodium salt 是一种有机阴离子染料,能够参与药物和代谢物的运输,可用于研究动物组织中表达的多种膜载体。
T26086L (Iso)-Rilmakalim

Others Others
1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one 是 Rilmakalim 的异构体,Rilmakalim 是一种钾通道打开剂 (PCO),可以激活心脏或其它组织中 ATP-敏感 K+ 通道
T67981 Copper histidine

Others Others
Copper histidine 抑制了Ctr1介导的奥沙利铂在体外的细胞摄取,而不会改变奥沙利铂在体内DRG 组织中的铂或神经毒性的积累。Copper histidine 通过口服治疗 Menkes 疾病。
T7423 Diquafosol tetrasodium

地夸磷索四钠,INS365

P2Y Receptor GPCR/G Protein; Neuroscience
Diquafosol tetrasodium (INS365) 是一种 P2Y2 受体激动剂,可刺激眼组织粘蛋白的分泌。它可改善泪膜稳定性和视觉功能,作为干眼症的局部治疗。
TP2308 TB500 acetate(885340-08-9 free base)

Frag17-23 Acetate,TB500 Acetate

Others Others
TB500 acetate(885340-08-9 free base) (Frag17-23 Acetate) 是胸腺素 β4 活性区域的合成版本。它促进内皮细胞分化、真皮组织中的血管生成、角质形成细胞迁移、胶原沉积和减少炎症。
T78268 Anti-Mouse NK1.1 Antibody (PK136)

Anti-Mouse NK1.1 Antibody (PK136) 是鼠源靶向 NK1.1的IgG2a类抗体,可消除外周血、脾脏和肺组织中的NK1.1和NK1.1NKT细胞,抑制 NK1.1 信号传导,可用于研究心肺衰竭。
T16333 NKY80

Adenylyl cyclase type V Inhibitor

Adenylyl cyclase Neuroscience
NKY80 调节心脏和肺组织中的腺苷酸环化酶催化活性。 NKY80 是腺苷酸环化酶 V 型亚型的非竞争性抑制剂(IC50 值:V、III 和 II 型分别为 8.3 µM、132 µM 和 1.7 mM)。
T10073 2-Iodomelatonin

Melatonin Receptor GPCR/G Protein
2-Iodomelatonin 是褪黑激素受体 1 (MT1) 的强效激动剂,Ki 为 28 pM,对 MT1的选择性是 MT2 的 5 倍以上。2-Iodomelatonin 可用于鉴定,表征和定位脑和周围组织的褪黑激素结合位点。
T2134 Dorzolamide hydrochloride

MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl

Carbonic Anhydrase Metabolism
Dorzolamide hydrochloride (MK507 hydrochloride) 是一种碳酸酐酶carbonic anhydrase II 抑制剂,能够抑制红细胞CA-II(IC50:0.18 nM) 和CA-I(IC50:600 nM) 。
T1229 Erdosteine

厄多司坦,RV 144,KW-9144

NF-κB; Antibacterial; Adenosine deaminase Metabolism; Microbiology/Virology; NF-κB
Erdosteine (RV 144) 抑制脂多糖诱导的NF-κB 激活,具有粘液调节、抗菌、抗炎、抗氧化和自由基清除作用。
T5095 Oxazolone

4-乙氧基亚甲基-2-苯基-2-唑啉-5-酮,4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

Others Others
Oxazolone 已被用作半抗原化剂,可在成年斑马鱼肠道组织中诱导炎症反应,并可用作两种形式的炎症性肠病(如克罗恩病和溃疡性结肠炎)的基因表达研究模型。
TP1844L Small Cardioactive Peptide B SCPB acetate

Small Cardioactive Peptide B SCPB acetate(84746-43-0 free base)

Others Others
Small Cardioactive Peptide B SCPB acetate (Small Cardioactive Peptide B SCPB acetate (84746-43-0 free base)) 是一种神经活性肽,可刺激心脏和鳃组织颗粒部分的腺苷酸环化酶活性,EC50 分别为 0.1 和 1.0 μM。
T6273 Vadimezan

DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Influenza Virus; VDA; STING; IFNAR Angiogenesis; Immunology/Inflammation; Microbiology/Virology
Vadimezan (DMXAA) 是一种血管破坏剂,一种鼠 STING 激动剂,也是一种细胞因子如 I 型 IFN 的诱导剂。Vadimezan 具有抗肿瘤活性,可以诱导肿瘤中的血流快速停止,但不影响正常组织中的血流。
T61202 TDO-IN-1

Others Others
TDO-IN-1 是一种具有口服活性、有效性和选择性的色氨酸 2,3-双加氧酶 (TDO)抑制剂 ,对吲哚胺-2,3-双加氧酶 具有抑制作用。TDO-IN-1 具有抗肿瘤活性, 能够通过逆转肿瘤组织的局部免疫耐受来发挥作用。
T60839 SLMP53-1

p53 Apoptosis
SLMP53-1 是一种 p53 激活剂, 具有抗肿瘤活性,抑制 wt 和 mutp53,激活异种移植人肿瘤组织中葡萄糖代谢的重编程,干扰血管生成和迁移。SLMP53-1 抑制肿瘤细胞生长,可用于研究人直肠癌。
T39695 ARD-2128

Androgen Receptor; PROTACs Endocrinology/Hormones; PROTAC
ARD-2128 是高效的雄激素受体降解剂 PROTAC。它可有效降低 雄激素受体蛋白并抑制肿瘤组织中雄激素受体调节的基因,在没有毒性迹象的情况下抑制肿瘤生长。它有用于前列腺癌研究的价值。
T1167 Cyproterone acetate

Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮

Androgen Receptor Endocrinology/Hormones
Cyproterone acetate (Cyproterone 17-O-acetate) 是能够抗雄激素(IC50=7.1 nM) 和孕激素合成的类固醇。它与 progesteron 和糖皮质激素受体有亲和力。
T23280 Ruthenium Red

钌红,Ammoniated ruthenium oxychloride

Calcium Channel Membrane transporter/Ion channel; Metabolism
Ruthenium Red (Ammoniated ruthenium oxychloride) 是一种 L 型钙电流 (ICa) 阻断剂,是一种聚阳离子染料,广泛用于电子显微镜 (EM) 下细胞、组织和营养细菌的观察。它能与磷脂和脂肪酸反应强烈,并与酸性粘多糖结合。
TP1280 Hexa-His

Others Others
Hexa-His 是融合蛋白的金属结合位点,是一种由 6 个组氨酸构成的六肽。
T37207L Cdk5 Substrate acetate

CDK Cell Cycle/Checkpoint
Cdk5 Substrate acetate 是一种丝氨酸/苏氨酸激酶,主要在神经元组织中具有活性。与 p25 或 p35 一起,Cdk5 磷酸化一系列蛋白质,包括组蛋白 H1 和 tau。 它是一种合成肽 (PKTPKKAKKL),对应于组蛋白 H1 的序列。它被 Cdk5 磷酸化,Km 值为 5 µM。
T22540L Ac-Endothelin-1 (16-21), human acetate

Others Others
Ac-Endothelin-1 (16-21), human acetate 是内皮素家族的主要肽,已被证明在血管和非血管组织中具有多种生物活性。 C-末端片段是 ET 家族肽中高度保守的序列,已显示可区分称为 ETA 和 ETB 的两种 ET 受体亚型,因为它仅激活后者。
T82252 GTPγS tetralithium

Guanosine 5'-[γ-thio]triphosphate tetralithium

Others Others
GTPγS tetralithium (Guanosine 5'-[γ-thio]triphosphate tetralithium) 是一种 G 蛋白激活剂,是一种不可水解 GTP 类似物,可保护蛋白质免遭蛋白水解降解。GTPγS tetralithium 参与检测表达重组受体的细胞以及表达内源性受体的细胞和组织中GPCR信号传导,可测定用于测量激动剂诱导的两种人多态性 α2B-肾上腺素受体变体的脱敏。
T3354 BIA 10-2474

BIA10-2474

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
BIA 10-2474 是一种长效可逆的脂肪酸酰胺水解酶抑制剂,与人类内源性大麻素系统相互作用,可增加中枢神经系统和外周组织,对大鼠大脑不同区域的 IC50值为50至70mg/kg。它用于治疗焦虑症、帕金森氏病和多发性硬化症、高血压或肥胖症的慢性疼痛。
T124358 Deferoxamine

Deferoxamine B,Desferrioxamine B

Apoptosis; Antioxidant; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; oxidation-reduction
Deferoxamine(Desferrioxamine B) 是一种铁螯合剂 (结合 Fe(III) 和许多其他金属阳离子),可抑制神经元病变,可用于改减少铁在组织中的积累和沉积,可通过抑制创伤性脑损伤后的铁死亡和神经炎症来改善神经功能障碍。Desferrioxamin-B 具有抗氧化、抗增殖、抗肿瘤活性,可诱导 HIF-1α 产生,诱导癌细胞凋亡和自噬。Desferrioxamin-B 可用于治疗急性铁中毒和与 COVID-19 相关疾病。
T14017 2-NBDG

2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖

Others Others
2-NBDG 是一种荧光指示剂 (λex=467 nm,λem=542 nm),是一种荧光 D-葡萄糖类似物。2-NBDG 可用于监测活细胞和组织中的葡萄糖吸收,可以通过实时共聚焦、高分辨率或宽视场荧光显微镜和流式细胞术进行监测。
T29209 ZD4190 HCl

ZD-4190,ZD-4190 HCl,ZD 4190,ZD4190,ZD-4190 hydrochloride

Others Others
ZD-4190, a potent VEGFR inhibitor, prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues.
T34559 SC-53116

SC 53116 HCl,SC53116 HCl

Others Others
SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.
T30750 Carnosine nitrate

(+)-Carnosine nitrate

Others Others
Carnosine nitrate is a dipeptide molecule. It is highly concentrated in muscle and brain tissues.
T69053 ANAPP3

Others Others
ANAPP3 is a P2x-purinoceptor antagonist. It affects contractions in various muscle groups and tissues.
T84569 Thromboxane B3

Δ17-TXB2

Others Others
Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.
T19465 N6-Etheno 2'-deoxyadenosine

Others Others
N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.
T85064 1-1(Z)-Hexadecenyl-2-Palmitoyl-sn-glycero-3-PC

1-1(Z)-Hexadecenyl-2-Hexadecanoyl-sn-glycero-3-Phosphocholine,PC(P-16:0/16:0),C16(plasm)-16:0-PC,16:0p/16:0-PC,1-1(Z)-Hexadecenyl-2-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine

Others Others
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC, a plasmalogen, appears in various rat tissues including the liver, heart, kidney, and both gluteus and soleus muscles, as well as visceral and subcutaneous adipose tissues. It serves in lipid bilayer synthesis to investigate how amphiphilic compounds, like lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC) and lysoplasmenylcholine, influence membrane dynamics.
T20908 Benzathine

Benzatin,AI3-23851,NSC 5632

Others Others
Benzathine is a diamine used as a component in some medications including benzathine benzylpenicillin and benzathine phenoxymethylpenicillin. When injected into tissues, it stabilizes penicillin and prolongs its sojourn.
T26230 Stilbamidine dihydrochloride

NSC 35605,NCI 174

Others Others
Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection.
T19211 BM152054

Others Others
BM152054 是一种有效的 PPARγ配体,可以通过加强胰岛素作用来诱导外周组织对葡萄糖的利用。

化合物

Carcinoembryonic Antigen CEA
Cat.No: TP1286
Synonym: 癌胚抗原
Target: Others
Sulfasalazine
Cat.No: T0907
Synonym: 柳氮磺吡啶,NSC 667219,Azulfidine
Target: Apoptosis, Ferroptosis, NF-κB, COX, Antibacterial, Antibiotic, Autophagy
Hexapeptide-9 Acetate
Cat.No: TP2492
Synonym: Hexapeptide-9 Acetate(1228371-11-6 Free base)
Target: Others
Bicalutamide
Cat.No: T0380
Synonym: 比卡鲁胺,ICI-176334
Target: Androgen Receptor, Autophagy
KL201
Cat.No: T9608
Synonym:
Target: Others
Amifostine thiol dihydrochloride
Cat.No: TQ0133
Synonym: WR 1065,硫代乙基氨基乙基胺盐酸盐
Target: p53
SW033291
Cat.No: T2121
Synonym:
Target: Dehydrogenase
Nicodan Percutan
Cat.No: T25867
Synonym: Nicotinic acid, propyl ester,Propylnicotinat,烟酸丙酯,Propyl pyridine-3-carboxylate,n-Propyl nicotinate,NSC-78447,NSC 78447,NSC78447
Target: Others
Lats-IN-1
Cat.No: T9053
Synonym:
Target: Others, YAP
1-Aminohydantoin hydrochloride
Cat.No: T0668
Synonym:
Target: Others
Clobetasone butyrate
Cat.No: T14981
Synonym:
Target: Glucocorticoid Receptor
Gadopentetate dimeglumine
Cat.No: T4506
Synonym: Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt
Target: Others
Solvent Blue 35
Cat.No: T19057
Synonym: Sudan Blue II,溶剂蓝35,溶剂蓝 35,Oil Blue 35
Target: Others
Light Green SF Yellowish
Cat.No: T20913
Synonym: Acid Green 5,C.I. Acid Green 5,C.I. 42095
Target:
Oxmetidine
Cat.No: T68122
Synonym: SKF 92994,Oxmetidina,Oxmetidinum
Target: Histamine Receptor
Sulfobromophthalein disodium salt
Cat.No: TD0105
Synonym:
Target: Others
(Iso)-Rilmakalim
Cat.No: T26086L
Synonym:
Target: Others
Copper histidine
Cat.No: T67981
Synonym:
Target: Others
Diquafosol tetrasodium
Cat.No: T7423
Synonym: 地夸磷索四钠,INS365
Target: P2Y Receptor
TB500 acetate(885340-08-9 free base)
Cat.No: TP2308
Synonym: Frag17-23 Acetate,TB500 Acetate
Target: Others
Anti-Mouse NK1.1 Antibody (PK136)
Cat.No: T78268
Synonym:
Target:
NKY80
Cat.No: T16333
Synonym: Adenylyl cyclase type V Inhibitor
Target: Adenylyl cyclase
2-Iodomelatonin
Cat.No: T10073
Synonym:
Target: Melatonin Receptor
Dorzolamide hydrochloride
Cat.No: T2134
Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl
Target: Carbonic Anhydrase
Erdosteine
Cat.No: T1229
Synonym: 厄多司坦,RV 144,KW-9144
Target: NF-κB, Antibacterial, Adenosine deaminase
Oxazolone
Cat.No: T5095
Synonym: 4-乙氧基亚甲基-2-苯基-2-唑啉-5-酮,4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
Target: Others
Small Cardioactive Peptide B SCPB acetate
Cat.No: TP1844L
Synonym: Small Cardioactive Peptide B SCPB acetate(84746-43-0 free base)
Target: Others
Vadimezan
Cat.No: T6273
Synonym: DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404
Target: Influenza Virus, VDA, STING, IFNAR
TDO-IN-1
Cat.No: T61202
Synonym:
Target: Others
SLMP53-1
Cat.No: T60839
Synonym:
Target: p53
ARD-2128
Cat.No: T39695
Synonym:
Target: Androgen Receptor, PROTACs
Cyproterone acetate
Cat.No: T1167
Synonym: Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮
Target: Androgen Receptor
Ruthenium Red
Cat.No: T23280
Synonym: 钌红,Ammoniated ruthenium oxychloride
Target: Calcium Channel
Hexa-His
Cat.No: TP1280
Synonym:
Target: Others
Cdk5 Substrate acetate
Cat.No: T37207L
Synonym:
Target: CDK
Ac-Endothelin-1 (16-21), human acetate
Cat.No: T22540L
Synonym:
Target: Others
GTPγS tetralithium
Cat.No: T82252
Synonym: Guanosine 5'-[γ-thio]triphosphate tetralithium
Target: Others
BIA 10-2474
Cat.No: T3354
Synonym: BIA10-2474
Target: FAAH, Autophagy
Deferoxamine
Cat.No: T124358
Synonym: Deferoxamine B,Desferrioxamine B
Target: Apoptosis, Antioxidant, HIF, Autophagy
2-NBDG
Cat.No: T14017
Synonym: 2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖
Target: Others
ZD4190 HCl
Cat.No: T29209
Synonym: ZD-4190,ZD-4190 HCl,ZD 4190,ZD4190,ZD-4190 hydrochloride
Target: Others
SC-53116
Cat.No: T34559
Synonym: SC 53116 HCl,SC53116 HCl
Target: Others
Carnosine nitrate
Cat.No: T30750
Synonym: (+)-Carnosine nitrate
Target: Others
ANAPP3
Cat.No: T69053
Synonym:
Target: Others
Thromboxane B3
Cat.No: T84569
Synonym: Δ17-TXB2
Target: Others
N6-Etheno 2'-deoxyadenosine
Cat.No: T19465
Synonym:
Target: Others
1-1(Z)-Hexadecenyl-2-Palmitoyl-sn-glycero-3-PC
Cat.No: T85064
Synonym: 1-1(Z)-Hexadecenyl-2-Hexadecanoyl-sn-glycero-3-Phosphocholine,PC(P-16:0/16:0),C16(plasm)-16:0-PC,16:0p/16:0-PC,1-1(Z)-Hexadecenyl-2-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine
Target: Others
Benzathine
Cat.No: T20908
Synonym: Benzatin,AI3-23851,NSC 5632
Target: Others
Stilbamidine dihydrochloride
Cat.No: T26230
Synonym: NSC 35605,NCI 174
Target: Others
BM152054
Cat.No: T19211
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TMS2180 Zeaxanthin

Anchovyxanthin,All-Trans-Zeaxanthin,玉米

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
Zeaxanthin (All-Trans-Zeaxanthin) 是食物获得类胡萝卜素,存在于眼睛的黄斑部,具有抗氧化活性。
T7647 Eicosadienoic acid

二十碳二烯酸,11,14-二十碳二烯酸C20:2

Endogenous Metabolite Metabolism
Eicosadienoic acid 是天然存在的 n-6 多不饱和脂肪酸,主要再动物组织中获得。
T4710 3-Methoxytyramine hydrochloride

3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐

Others; Endogenous Metabolite; Drug Metabolite Metabolism; Others
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物,能够活化痕量胺相关受体1 。
T0434 D-Glucuronic acid lactone

Glucuronolactone,D-Glucurone,Dicurone,葡醛内酯

Others; Endogenous Metabolite Metabolism; Others
D-Glucuronic acid lactone (Dicurone) 是内源性代谢产物的一种。
T4945 Normetanephrine hydrochloride

DL-Normetanephrine hydrochloride,DL-去甲变肾上腺素盐酸盐

Endogenous Metabolite Metabolism
Normetanephrine hydrochloride (DL-Normetanephrine hydrochloride) 是肾上腺素的代谢物。它与肾上腺素一起存在于尿液和某些组织中。
T12297 Oleuropeinic acid

Others Others
Oleuropeinic acid 是一种抗氧化剂可溶性纤维,存在于橄榄组织中或通过热处理形成,可能是由橄榄苦苷的氧化形成。
T0022 Taurine

牛磺酸,2-Aminoethanesulfonic acid

LDL; Endogenous Metabolite; Autophagy Autophagy; Metabolism
Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。
T4804 Pyruvic acid

BTS,Pyroracemic acid,α-Ketopropionic acid,2-Oxopropionic acid,Acetylformic acid,丙酮酸,NSC 179

Others; Endogenous Metabolite Metabolism; Others
Pyruvic acid (Acetylformic acid) 是碳水化合物,是蛋白质和脂肪代谢的中间产物。
T0937 Riboflavin

Vitamin B2,维生素B2,E101

Endogenous Metabolite Metabolism
Riboflavin (E101),一种人内源性代谢物, 是极易吸收的微量营养素。
T3405 [6]-Gingerol

6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
[6]-Gingerol ((S)-(+)-[6]Gingerol) 是一种从生姜中分离的活性物质,具有抗癌,抗炎和抗氧化活性。
T3007 Spermine

Gerontine,Musculamine,精胺,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine

Influenza Virus; Endogenous Metabolite Metabolism; Microbiology/Virology
Spermine (Neuridine) 作为一个直接的自由基清除剂,具有抗病毒作用,能够保护 DNA 免受自由基的攻击。
TL0006 Cichoric Acid

菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物,具有抗氧化作用。
T2O2733 L-Cystine

Cystine Acid,cystine,胱氨酸,L-胱氨酸

Antioxidant; Ferroptosis; Endogenous Metabolite Apoptosis; Metabolism; oxidation-reduction
L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用,保护组织免受辐射和污染,减缓衰老过程。它还有助于蛋白质合成。
T5232 3-Methyl-2-oxobutanoic acid

3-甲基-2-氧丁酸,2-Oxoisovaleric acid,alpha-Ketoisovaleric acid

Others; Endogenous Metabolite Metabolism; Others
3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) 是大肠杆菌中泛酸的前体。它是由支链氨基酸的不完全分解产生的一种异常代谢物。
T5S0734 Desmethoxyyangonin

Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain

Others; Monoamine Oxidase Neuroscience; Others
Desmethoxyyangonin (5,6-Dehydrokavain) 是一种MAO-B 可逆性抑制剂。
TN1343 8-Geranyloxypsoralen

8-香叶草氧基补骨脂素

Anti-infection; P450; BACE Metabolism; Microbiology/Virology; Neuroscience
8-Geranyloxypsoralen 是一种呋喃香豆素,分离自葡萄柚,是 P450 3A4 的有效抑制剂(IC50:3.93 μM)。
T6491 (-)-(S)-Equol

(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。
TN7244 Egg PG

Phosphatidylglycerols(egg)

Egg PG(Phosphatidylglycerols(egg)) 是一种食物和生物组织的主要磷脂酰甘油之一,常存在于细菌和动物细胞的膜中,可作为 sPMCA,反应中的阴离子磷脂底物。
T1658 Selenomethionine

DL-Selenomethionine,DL-硒代蛋氨酸,Seleno-DL-methionine,硒代蛋氨酸

Amino Acids and Derivatives; Endogenous Metabolite; Autophagy Autophagy; Metabolism
Selenomethionine (Seleno-DL-methionine) 是一种硒代氨基酸,是蛋氨酸的硒类似物。 它具有作为植物代谢物的作用。 它是硒代蛋氨酸和硒代氨基酸的成员。
T4814 (R)-5-Oxopyrrolidine-2-carboxylic acid

D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸

Others; Endogenous Metabolite Metabolism; Others
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) 是内源性代谢产物的一种。
T8948 Ferroheme

protoheme,Hematin,heme

Others Others
Ferroheme (protoheme) 是一种亚铁离子和卟啉的复合物,也是脂肪酸结合大鼠肝脏脂肪酸结合蛋白的同位异构抑制剂。
T0879 Niacin

Vitamin B3,烟酸(维生素B3),Nicotinic acid

Endogenous Metabolite; Autophagy Autophagy; Metabolism
Niacin (Nicotinic acid),也称为烟酸和维生素 B3,是一种水溶性必需的 B 族维生素,用于治疗维生素缺乏症以及高脂血症,血脂异常,高甘油三酯血症,并降低心肌梗塞的风险
TN1003 DL-Alanine

DL-2-Aminopropionic acid

Endogenous Metabolite Metabolism
DL-Alanine (DL-2-Aminopropionic acid) 是一种氨基酸,是L-和D-丙氨酸的外消旋化合物。DL-Alanine 与硝酸银水溶液一起用于纳米颗粒生成时常作为还原剂和封端剂。DL-Alanine 是一种甜味剂,可把它位与甘氨酸和糖精钠归为一类。DL-Alanine 在组织和肝脏之间的葡萄糖-丙氨酸循环中起重要作用。DL-Alanine 可用于研究 Cu、Zn、Cd 等过渡金属螯合。
T0846 L-Carnitine

L(-)-Carnitine,Levocarnitine,左旋肉碱

Endogenous Metabolite; Fatty Acid Synthase Metabolism
L-Carnitine (L(-)-Carnitine) 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
T4704 L-Anserine nitrate

L-鹅肌肽硝酸盐,L-Anserine nitrate salt

Others; Endogenous Metabolite Metabolism; Others
L-Anserine nitrate (L-Anserine nitrate salt) 是一种存在于大多数动物组织中的二肽。在模型系统中,它是一种有效的抗氧化剂和羟基自由基清除剂。该化合物抑制醛糖和酮糖还原糖诱导的非酶蛋白糖基化。
T8264 3-Methyl-2-oxovaleric acid

Endogenous Metabolite Metabolism
3-Methyl-2-oxovaleric acid 是神经毒素,代谢毒素和酸性原,它是支链氨基酸不完整分解产生的异常代谢物。
T0665 Xanthine

2,6-Dihydroxypurine,海生丁(黄嘌呤),黄嘌呤,Isoxanthine

Endogenous Metabolite; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Xanthine (Isoxanthine) 是一种植物生物碱,存在于茶、咖啡和可可中。Xanthine 是温和的中枢神经系统激活剂,也是嘌呤降解途径的中间产物。
T4685 INOSINIC ACID

Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P

Endogenous Metabolite Metabolism
Inosinic acid (IMP) 是内源性代谢产物。
T5004 Hyaluronic acid sodium

透明质酸钠,Sodium Hyaluronate

Others Others
Hyaluronic acid sodium (Sodium Hyaluronate) 是一种生物聚合物,由二糖的重复单元组成,应用领域广泛。
T41245 Trimethylamine N-oxide

Reactive Oxygen Species; NOD-like Receptor (NLR); TGF-beta/Smad Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
Trimethylamine N-oxide (TMAO) 是由胆碱、甜菜碱和肉碱通过肠道微生物代谢产生的一种无色氧化胺,积聚在海洋动物的组织中,可预防尿素对蛋白质的破坏作用。Trimethylamine N-oxide 通过激活 ROS/NLRP3 炎性体诱导炎症,可诱导纤维细胞的分化和心脏纤维化。
T2A2532 L-Histidine

Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Mitochondrial Metabolism; Endogenous Metabolite Metabolism
L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T6480 D-Pantothenic acid

vitamin B5,pantothenate,D-泛酸

Others Others
D-Pantothenic acid (vitamin B5) 是必需的微量营养素,是辅酶 A 的前体,在很多生物过程中发挥关键作用,如调节碳水化合物,脂质,蛋白和核酸代谢。
T0848 L-DOPA

左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine

Dopamine Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism; Neuroscience
L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体,具有口服活性。Levodopa 能够透过血脑屏障,并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。
T4883 Creatine

Methylguanidoacetic acid,肌酸

Endogenous Metabolite Metabolism
Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。
T5306 H-Abu-OH

L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid

Others; Endogenous Metabolite Metabolism; Others
H-Abu-OH (L-α-amino-n-Butyric acid) 是氨基丁酸的三个同分异构体之一,它在患有雷氏综合征,同型血尿症,酪氨酸血症,非酮糖症以及鸟氨酸转氨酶症等代谢病儿童的血浆中的含量会明显升高。
T5074 Cholesteryl palmitate

Others; Endogenous Metabolite Metabolism; Others
Cholesteryl palmitate 是一种慢性间质性肺炎的有用预后生物标志物。
T4947 3-Hydroxybutyric acid

Butanoic acid,3-羟基丁酸

Endogenous Metabolite Metabolism
3-Hydroxybutyric acid (Butanoic acid) 是一种人内源性代谢物,在 I 型糖尿病中升高。它能够调节膜脂的性质。
T4893 Spermidine

N-(3-Aminopropyl)-1,4-diaminobutane,亚精胺,N-(4-Aminobutyl)-1,3-diaminopropane

Endogenous Metabolite Metabolism
Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) 属于天然多胺,存在于核糖体和活组织中,在生物体内具有各种代谢功能。Spermidine 具有炎症减轻、调节脂质代谢、调节细胞生长和死亡的功能。
T1183 Retinol

all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin

Others Others
Retinol (Vitamin A) 属于天然维生素,具有脂溶性。Retinol 在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。
T12996 Squalamine lactate

MSI-1256F

Others Others
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.
T82792 Caffeoyl-CoA

Caffeoyl-CoA,其Km值为1.45 μm,可从禾本科植物的叶组织提取。
T0879L Niacin hydrochloride

Niacin hydrochloride is a water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is needed by the body for the formation of coenzymes NAD and NADP. It possesses PELLAGRA-curative, vasodilating, and antilipemic properties.
TN4062 Flavidin

COX; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should have wide application in molecular detection, providing a general insight into how to optimiz
T37972 12-OxoETE

Others Others
12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via a leukotriene B4 receptor or a common activation sequence.
T83405 2,3-Diphosphoglyceric acid

2,3-DPG

Others Others
2,3-Diphosphoglyceric acid (2,3-DPG) 是一种糖酵解途径的中间产物,能够通过变构作用结合并稳定脱氧血红蛋白,从而促进氧气在组织部位的释放。此外,2,3-Diphosphoglyceric acid 与血红蛋白结合,有效降低了其对氧的亲和力。
T83274 6′-Galactosyllactose

6′-Galactosyllactose是人乳中半乳糖主要的低聚糖成分,它能与3′-Galactosyllactose和4′-Galactosyllactose结合,合成人乳低聚糖和半乳糖人工低聚糖,从而减缓T84、NCM-460和H4细胞以及肠道组织的炎症反应。
TN4997 Serpentine

IGF-1R Tyrosine Kinase/Adaptors
Serpentine 是一种玫瑰花根中的生物碱,可用作胰岛素增敏剂,以协助胰岛素降低血糖。Serpentine 可激活 AMPK 磷酸化,从而刺激C2C12细胞对葡萄糖的摄取。Serpentine 可增加了肌肉组织中GSK-3β mRNA的表达,从而增强葡萄糖摄取。Serpentine 显著增加胰高血糖素分泌和肝糖异生。在高脂肪饮食/链脲佐菌素(HFD/STZ)诱导的糖尿病小鼠中,Serpentine 显著延长了胰岛素的降血糖时间,显著降低了外源性胰岛素的使用,抑制了内源性胰岛素的分泌。
T35415 α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

Others Others
α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...

天然产物

Zeaxanthin
Cat.No: TMS2180
Synonym: Anchovyxanthin,All-Trans-Zeaxanthin,玉米
Target: Antioxidant, Endogenous Metabolite
Eicosadienoic acid
Cat.No: T7647
Synonym: 二十碳二烯酸,11,14-二十碳二烯酸C20:2
Target: Endogenous Metabolite
3-Methoxytyramine hydrochloride
Cat.No: T4710
Synonym: 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐
Target: Others, Endogenous Metabolite, Drug Metabolite
D-Glucuronic acid lactone
Cat.No: T0434
Synonym: Glucuronolactone,D-Glucurone,Dicurone,葡醛内酯
Target: Others, Endogenous Metabolite
Normetanephrine hydrochloride
Cat.No: T4945
Synonym: DL-Normetanephrine hydrochloride,DL-去甲变肾上腺素盐酸盐
Target: Endogenous Metabolite
Oleuropeinic acid
Cat.No: T12297
Synonym:
Target: Others
Taurine
Cat.No: T0022
Synonym: 牛磺酸,2-Aminoethanesulfonic acid
Target: LDL, Endogenous Metabolite, Autophagy
Pyruvic acid
Cat.No: T4804
Synonym: BTS,Pyroracemic acid,α-Ketopropionic acid,2-Oxopropionic acid,Acetylformic acid,丙酮酸,NSC 179
Target: Others, Endogenous Metabolite
Riboflavin
Cat.No: T0937
Synonym: Vitamin B2,维生素B2,E101
Target: Endogenous Metabolite
[6]-Gingerol
Cat.No: T3405
Synonym: 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚
Target: Apoptosis, AMPK
Spermine
Cat.No: T3007
Synonym: Gerontine,Musculamine,精胺,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine
Target: Influenza Virus, Endogenous Metabolite
Cichoric Acid
Cat.No: TL0006
Synonym: 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid
Target: Reactive Oxygen Species, HIV Protease
L-Cystine
Cat.No: T2O2733
Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸
Target: Antioxidant, Ferroptosis, Endogenous Metabolite
3-Methyl-2-oxobutanoic acid
Cat.No: T5232
Synonym: 3-甲基-2-氧丁酸,2-Oxoisovaleric acid,alpha-Ketoisovaleric acid
Target: Others, Endogenous Metabolite
Desmethoxyyangonin
Cat.No: T5S0734
Synonym: Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain
Target: Others, Monoamine Oxidase
8-Geranyloxypsoralen
Cat.No: TN1343
Synonym: 8-香叶草氧基补骨脂素
Target: Anti-infection, P450, BACE
(-)-(S)-Equol
Cat.No: T6491
Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Egg PG
Cat.No: TN7244
Synonym: Phosphatidylglycerols(egg)
Target:
Selenomethionine
Cat.No: T1658
Synonym: DL-Selenomethionine,DL-硒代蛋氨酸,Seleno-DL-methionine,硒代蛋氨酸
Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy
(R)-5-Oxopyrrolidine-2-carboxylic acid
Cat.No: T4814
Synonym: D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸
Target: Others, Endogenous Metabolite
Ferroheme
Cat.No: T8948
Synonym: protoheme,Hematin,heme
Target: Others
Niacin
Cat.No: T0879
Synonym: Vitamin B3,烟酸(维生素B3),Nicotinic acid
Target: Endogenous Metabolite, Autophagy
DL-Alanine
Cat.No: TN1003
Synonym: DL-2-Aminopropionic acid
Target: Endogenous Metabolite
L-Carnitine
Cat.No: T0846
Synonym: L(-)-Carnitine,Levocarnitine,左旋肉碱
Target: Endogenous Metabolite, Fatty Acid Synthase
L-Anserine nitrate
Cat.No: T4704
Synonym: L-鹅肌肽硝酸盐,L-Anserine nitrate salt
Target: Others, Endogenous Metabolite
3-Methyl-2-oxovaleric acid
Cat.No: T8264
Synonym:
Target: Endogenous Metabolite
Xanthine
Cat.No: T0665
Synonym: 2,6-Dihydroxypurine,海生丁(黄嘌呤),黄嘌呤,Isoxanthine
Target: Endogenous Metabolite, Adenosine Receptor
INOSINIC ACID
Cat.No: T4685
Synonym: Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P
Target: Endogenous Metabolite
Hyaluronic acid sodium
Cat.No: T5004
Synonym: 透明质酸钠,Sodium Hyaluronate
Target: Others
Trimethylamine N-oxide
Cat.No: T41245
Synonym:
Target: Reactive Oxygen Species, NOD-like Receptor (NLR), TGF-beta/Smad
L-Histidine
Cat.No: T2A2532
Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine
Target: Mitochondrial Metabolism, Endogenous Metabolite
D-Pantothenic acid
Cat.No: T6480
Synonym: vitamin B5,pantothenate,D-泛酸
Target: Others
L-DOPA
Cat.No: T0848
Synonym: 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine
Target: Dopamine Receptor, Endogenous Metabolite
Creatine
Cat.No: T4883
Synonym: Methylguanidoacetic acid,肌酸
Target: Endogenous Metabolite
H-Abu-OH
Cat.No: T5306
Synonym: L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid
Target: Others, Endogenous Metabolite
Cholesteryl palmitate
Cat.No: T5074
Synonym:
Target: Others, Endogenous Metabolite
3-Hydroxybutyric acid
Cat.No: T4947
Synonym: Butanoic acid,3-羟基丁酸
Target: Endogenous Metabolite
Spermidine
Cat.No: T4893
Synonym: N-(3-Aminopropyl)-1,4-diaminobutane,亚精胺,N-(4-Aminobutyl)-1,3-diaminopropane
Target: Endogenous Metabolite
Retinol
Cat.No: T1183
Synonym: all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin
Target: Others
Squalamine lactate
Cat.No: T12996
Synonym: MSI-1256F
Target: Others
Caffeoyl-CoA
Cat.No: T82792
Synonym:
Target:
Niacin hydrochloride
Cat.No: T0879L
Synonym:
Target:
Flavidin
Cat.No: TN4062
Synonym:
Target: COX, Prostaglandin Receptor
12-OxoETE
Cat.No: T37972
Synonym:
Target: Others
2,3-Diphosphoglyceric acid
Cat.No: T83405
Synonym: 2,3-DPG
Target: Others
6′-Galactosyllactose
Cat.No: T83274
Synonym:
Target:
Serpentine
Cat.No: TN4997
Synonym:
Target: IGF-1R
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
Cat.No: T35415
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-00272 RELT/TNFRSF19L Protein, Human, Recombinant (hFc)

RELT,TNFRSF19L,Receptor expressed in lymphoid tissues

Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane protein and contains one TNFR-Cys repeat. TNFRSF19L is highly expressed in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. It has been shown TNFRSF19L activates the NF-kappaB pathway and selectively binds TNF receptor-associated factor 1 (TRAF1)....
TMPY-04853 TSHR Protein, Human, Recombinant (His)

TSHR,hTSHR-I,TSH Receptor,LGR3,CHNG1

Human Baculovirus Insect Cells
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis.
TMPH-00010 MMP-14 Protein, Human, Recombinant (His & SUMO)

Membrane-type-1 matrix metalloproteinase,MMP14,Membrane-type...

Human E. coli
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to...
TMPK-00807 Osteopontin Protein, Mouse, Recombinant (His)

ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteopontin,Ne...

Mouse HEK293 Cells
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells.
TMPY-00021 PADI4 Protein, Human, Recombinant (His)

PADI5,PAD4,PDI4,peptidyl arginine deiminase, type IV,PAD,PDI...

Human Baculovirus Insect Cells
Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase family. PADI4 is expressed in CD34+stem cells in normal tissues, and many more CD34+ cells expressing PADI4 are present in tumour tissues. PADI4 post-translationally converts peptidylarginine to citrulline, a process called citrullination. Studies have demonstrated the high expres...
TMPY-05033 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)

5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4

Human HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641.
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi)

CD163,HbSR,RM3/1,MM130,CD163 molecule,GHI/61,sCD163,SCARI1,M...

Human HEK293 Cells
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. CD163 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 111.4 kDa and th...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1,Vascular perme...

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPY-03958 TGF alpha Protein, Human, Recombinant

transforming growth factor α,转化生长因子,transforming growth fact...

Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (...
TMPY-02483 ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

ATPCL,ACL,ATP citrate lyase,CLATP

Human Baculovirus Insect Cells
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show...
TMPY-02292 IGSF11 Protein, Human, Recombinant (His)

CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C...

Human HEK293 Cells
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep...
TMPY-05054 Notch 4 Protein, Human, Recombinant (His)

INT3,notch 4

Human Baculovirus Insect Cells
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is involved in the development and patterning of the central nervous systems. It regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene has also been identified as a possibl...
TMPY-04125 PTP1B Protein, Human, Recombinant (His)

protein tyrosine phosphatase, non-receptor type 1,PTP1B,PTPN...

Human E. coli
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein p...
TMPY-04989 Galectin-9 Protein, Human, Recombinant (hFc)

LGALS9A,lectin, galactoside-binding, soluble, 9,HUAT

Human HEK293 Cells
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or i...
TMPY-00322 DEC-205 Protein, Human, Recombinant (His)

GP200-MR6,CD205,CLEC13B,lymphocyte antigen 75,LY-75,DEC-205

Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s a...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant

NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3

Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)

APOL1,apolipoprotein L1,APOL,FSGS4,APOL-I,APO-L

Human Baculovirus Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer...
TMPJ-00038 IL-7 Protein, Mouse, Recombinant (His)

interleukin-7,白介素,IL-7,IL-7 interleukin-7,PBGF,Lymphopoietin...

Mouse HEK293 Cells
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His)

abhydrolase domain containing 4,ABH4

Human Baculovirus Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa...
TMPJ-01204 TPSAB1 Protein, Human, Recombinant (His)

TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1...

Human HEK293 Cells
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s...
TMPY-02707 PAH Protein, Human, Recombinant (415 Asn/Asp, His)

phenylalanine hydroxylase,PH,PKU1,PKU

Human Baculovirus Insect Cells
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding sites for phenylalanine and to constitute an "inhibitory" domain that regulates the activity of a catalytic domain in the C-terminal portion of the molecule. In humans, PAH is expressed both in the liver and the kidney, and there is some indication that it may be differentially reg...
TMPJ-00071 EPO/Erythropoietin Protein, Human, Recombinant (His)

Erythropoietin,EPO,红细胞生长素,Epoetin

Human HEK293 Cells
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP...
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...

Human HEK293 Cells
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His)

Nog,Noggin

Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi...
TMPY-02700 BCL2 Protein, Human, Recombinant (His)

Bcl-2,PPP1R50,B-cell CLL/lymphoma 2

Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPJ-01461 IL-15RA & IL-15 Protein, Human, Recombinant (hFc)

IL-15 Receptor α & IL-15 Fusion Protein,Interleukin-15,IL15R...

Human HEK293 Cells
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ...
TMPY-04552 AKT1 Protein, Human, Recombinant (His)

RAC-ALPHA,v-akt murine thymoma viral oncogene homolog 1,RAC,...

Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac...
TMPJ-01462 IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)

IL15,IL15RA&IL15,IL-15,Interleukin-15,IL-15 Receptor α & IL-...

Human HEK293 Cells
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ...
TMPY-04985 TMPRSS11D Protein, Human, Recombinant (His)

transmembrane protease, serine 11D,HAT

Human HEK293 Cells
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated with NSCLC patients' clinical characteristics and overall survival. Both TMPRSS11D mRNA and protein expression levels were significantly higher in NSCLC tumorous tissues than in adjacent normal tissues. High TMPRSS11D protein expression was associated with high TNM stages, and hi...
TMPK-00992 SEZ6L2 Protein, Mouse, Recombinant (His)

SEZ6L2,BSRP-A,PSK-1,UNQ1903/PRO4349

Mouse HEK293 Cells
Seizure-related 6 homolog (mouse)-like 2 (SEZ6L2) was shown to be involved in transcription of a type 1 transmembrane protein for regulating cell fate. SEZ6L2 was significantly up-regulated in tumour tissues of patients with CRC compared with adjacent normal tissues. Up-regulation of SEZ6L2 was correlated with a poor prognosis in patients with CRC. Furthermore, SEZ6L2 expression was inversely correlated with the expression of cytochrome C in malignant tissues in patients with CRC.
TMPY-00497 ZG16 Protein, Human, Recombinant (mFc)

JCLN1,zymogen granule protein 16,ZG16A,JCLN

Human HEK293 Cells
Zymogen granule protein 16 (ZG16) is one of the most significantly down-regulated genes in colorectal cancer (CRC) tissues. Proteomic analyses of mucus have identified the lectin-like protein ZG16 as an abundant mucus component, which is significantly decreased in CRC samples compared to adjacent non-tumor tissues and associated with prognosis of patients.
TMPH-00224 APOA1 Protein, Bovine, Recombinant (E. coli, His)

APOA1,Apolipoprotein A-I,ApoA-I,Apo-AI,Apolipoprotein A1

Bovine E. coli
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. APOA1 Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.6 kDa and the accession number is P15497.
TMPH-00225 APOA1 Protein, Bovine, Recombinant (His)

Apolipoprotein A-I,APOA1,ApoA-I,Apo-AI,Apolipoprotein A1

Bovine P. pastoris (Yeast)
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. APOA1 Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.5 kDa and the accession number is P15497.
TMPJ-00795 Growth Hormone Protein, Mouse, Recombinant

Gh1,Somatotropin,Gh,Growth Hormone

Mouse E. coli
Somatotropin(GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
TMPK-00163 IL-33 Protein, Cynomolgus, Recombinant (His)

IL1F11,C9orf26 Z,C9ORF26,DV27,RP11-575C20.2,NFEHEV,IL33,DVS2...

Cynomolgus HEK293 Cells
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.
TMPZ-00002 GH2 Protein, Human, Recombinant (His)

Growth hormone 2,Placenta-specific growth hormone

Human HEK294 Cells
GH2 Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.01 kDa and the accession number is P01242.
TMPK-01304 Kremen-2 Protein, Cynomolgus, Recombinant (His)

KREMEN2,KRM2,Dickkopf receptor 2,Kremen-2

Cynomolgus HEK293 Cells
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian c...
TMPH-02447 GH Protein, Rhesus macaque, Recombinant (His & Myc)

Growth hormone,Growth hormone 1,Somatotropin,GH1,Pituitary g...

Rhesus E. coli
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Rhesus macaque, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.7 kDa and the accession number is ...
TMPH-03127 GH Protein, Pig, Recombinant (His & Myc)

GH1,Growth hormone,Somatotropin

Sus scrofa (Pig) E. coli
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.4 kDa and the accession number is P01248.
TMPK-00509 E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)

E-Cadherin,Arc-1,L-CAM,E-CAD,Cadherin1,Cadherin-1,E Cadherin...

Cynomolgus HEK293 Cells
E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelial tissues.
TMPJ-01281 COL21A1 Protein, Human, Recombinant (His)

collagen, type XXI, alpha 1,COL21A1,FLJ44623,DKFZp564B052,co...

Human HEK293 Cells
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I collagen; it may serve to main...
TMPY-00193 ULBP-4 Protein, Human, Recombinant (hFc)

LETAL,bA350J20.7,RL-4,RAET1E2,retinoic acid early transcript...

Human HEK293 Cells
The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q8TD07-1.
TMPJ-01059 CRADD Protein, Human, Recombinant

Caspase and RIP Adapter with Death Domain,RAIDD,RIP-Associat...

Human E. coli
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numero...
TMPH-01818 CD200 Protein, Human, Recombinant (His & SUMO)

MOX1,OX-2 membrane glycoprotein,MOX2,CD200

Human E. coli
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. CD200 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.4 kDa and the accession number is P41217.
TMPK-00478 Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)

CA12,CAXII,Carbonic anhydrase,CA-XII,Tumor antigen HOM-RCC-3...

Cynomolgus HEK293 Cells
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in cancer development.
TMPK-01093 Kremen-2 Protein, Mouse, Recombinant (His)

KRM2,KREMEN2,Dickkopf receptor 2,Kremen-2

Mouse HEK293 Cells
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells ...
TMPK-01106 Kremen-2 Protein, Human, Recombinant (His)

KRM2,KREMEN2,Kremen-2,Dickkopf receptor 2

Human HEK293 Cells
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells ...
TMPJ-00243 Serpin B6 Protein, Human, Recombinant (E. coli, His)

CAP,PI6,SERPINB6,Placental Thrombin Inhibitor,Cytoplasmic An...

Human E. coli
Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and se...
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重组蛋白

RELT/TNFRSF19L Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00272
Species: Human
Expression System: HEK293 Cells
TSHR Protein, Human, Recombinant (His)
Cat.No: TMPY-04853
Species: Human
Expression System: Baculovirus Insect Cells
MMP-14 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00010
Species: Human
Expression System: E. coli
Osteopontin Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00807
Species: Mouse
Expression System: HEK293 Cells
PADI4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00021
Species: Human
Expression System: Baculovirus Insect Cells
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
Cat.No: TMPY-05033
Species: Human
Expression System: HEK293 Cells
CD163 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01074
Species: Human
Expression System: HEK293 Cells
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
TGF alpha Protein, Human, Recombinant
Cat.No: TMPY-03958
Species: Human
Expression System: E. coli
ATP citrate lyase/ACLY Protein, Human, Recombinant (His)
Cat.No: TMPY-02483
Species: Human
Expression System: Baculovirus Insect Cells
IGSF11 Protein, Human, Recombinant (His)
Cat.No: TMPY-02292
Species: Human
Expression System: HEK293 Cells
Notch 4 Protein, Human, Recombinant (His)
Cat.No: TMPY-05054
Species: Human
Expression System: Baculovirus Insect Cells
PTP1B Protein, Human, Recombinant (His)
Cat.No: TMPY-04125
Species: Human
Expression System: E. coli
Galectin-9 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04989
Species: Human
Expression System: HEK293 Cells
DEC-205 Protein, Human, Recombinant (His)
Cat.No: TMPY-00322
Species: Human
Expression System: HEK293 Cells
Neurotrophin 3 Protein, Human, Recombinant
Cat.No: TMPY-04069
Species: Human
Expression System: E. coli
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02956
Species: Human
Expression System: Baculovirus Insect Cells
IL-7 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00038
Species: Mouse
Expression System: HEK293 Cells
ABHD4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01460
Species: Human
Expression System: Baculovirus Insect Cells
TPSAB1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01204
Species: Human
Expression System: HEK293 Cells
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
Cat.No: TMPY-02707
Species: Human
Expression System: Baculovirus Insect Cells
EPO/Erythropoietin Protein, Human, Recombinant (His)
Cat.No: TMPJ-00071
Species: Human
Expression System: HEK293 Cells
FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293 Cells
Noggin/NOG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
BCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02700
Species: Human
Expression System: E. coli
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
IL-15RA & IL-15 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-01461
Species: Human
Expression System: HEK293 Cells
AKT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
Cat.No: TMPJ-01462
Species: Human
Expression System: HEK293 Cells
TMPRSS11D Protein, Human, Recombinant (His)
Cat.No: TMPY-04985
Species: Human
Expression System: HEK293 Cells
SEZ6L2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00992
Species: Mouse
Expression System: HEK293 Cells
ZG16 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00497
Species: Human
Expression System: HEK293 Cells
APOA1 Protein, Bovine, Recombinant (E. coli, His)
Cat.No: TMPH-00224
Species: Bovine
Expression System: E. coli
APOA1 Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00225
Species: Bovine
Expression System: P. pastoris (Yeast)
Growth Hormone Protein, Mouse, Recombinant
Cat.No: TMPJ-00795
Species: Mouse
Expression System: E. coli
IL-33 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00163
Species: Cynomolgus
Expression System: HEK293 Cells
GH2 Protein, Human, Recombinant (His)
Cat.No: TMPZ-00002
Species: Human
Expression System: HEK294 Cells
Kremen-2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01304
Species: Cynomolgus
Expression System: HEK293 Cells
GH Protein, Rhesus macaque, Recombinant (His & Myc)
Cat.No: TMPH-02447
Species: Rhesus
Expression System: E. coli
GH Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03127
Species: Sus scrofa (Pig)
Expression System: E. coli
E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00509
Species: Cynomolgus
Expression System: HEK293 Cells
COL21A1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01281
Species: Human
Expression System: HEK293 Cells
ULBP-4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00193
Species: Human
Expression System: HEK293 Cells
CRADD Protein, Human, Recombinant
Cat.No: TMPJ-01059
Species: Human
Expression System: E. coli
CD200 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01818
Species: Human
Expression System: E. coli
Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00478
Species: Cynomolgus
Expression System: HEK293 Cells
Kremen-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01093
Species: Mouse
Expression System: HEK293 Cells
Kremen-2 Protein, Human, Recombinant (His)
Cat.No: TMPK-01106
Species: Human
Expression System: HEK293 Cells
Serpin B6 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPJ-00243
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0009 1-Amino Hydantoin-13C3

1-Amino Hydantoin-13C3 是 1-Amino Hydantoin 的 13C 的标记化合物。1-Amino Hydantoin 的 CAS 号为 6301-02-6。1-Aminohydantoin 是一种呋喃妥因在动物组织中的主要代谢物。1-Aminohydantoin 与组织蛋白共价结合,在微酸性条件下从组织中释放出来,与 2-硝基苯甲醛衍生形成 AHD 的硝基苯基衍生物可被检测。1-Aminohydantoin 可作为测定肉、奶等兽药残留的测定指标。
TMIJ-0097 Sulfasalazine-d4

Sulfasalazine-d4 是 Sulfasalazine 的氘代化合物。Sulfasalazine 的 CAS 号为 599-79-1。Sulfasalazine 是一种合成的水杨酸衍生物,对含有弹性蛋白的结缔组织具有亲和力,并配制成前药。
TMID-0169 Taurine-d4

Taurine-d4 是 Taurine 的氘代化合物。Taurine 的 CAS 号为 107-35-7。Taurine 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。
T71302 Norfluoxetine-d5 HCl

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...
TMIJ-0101 DL-Alanine-2,3,3,3-d4

DL-Alanine-2,3,3,3-d4 是 DL-Alanine 的氘代化合物。DL-Alanine 的 CAS 号为 302-72-7。DL-Alanine 是一种氨基酸,是L-和D-丙氨酸的外消旋化合物。DL-Alanine 与硝酸银水溶液一起用于纳米颗粒生成时常作为还原剂和封端剂。DL-Alanine 是一种甜味剂,可把它位与甘氨酸和糖精钠归为一类。DL-Alanine 在组织和肝脏之间的葡萄糖-丙氨酸循环中起重要作用。DL-Alanine 可用于研究 Cu、Zn、Cd 等过渡金属螯合。
TMIJ-0090 L-Carnitine-d9

L-Carnitine-d9 是 L-Carnitine 的氘代化合物。L-Carnitine 的 CAS 号为 541-15-1。L-carnitine 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
T35783 Zearalenone-13C18

Zearalenone-13C18

Zearalenone-13C18is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also i...
T70960 Maprotiline-d3 hydrochloride

Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r...
TMID-0097 Ethyl-d5-malonic Acid

Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。
TMIJ-0312 L-Dopa-2,5,6-d3

L-Dopa-2,5,6-d3 是 L-Dopa 的氘代化合物。L-Dopa 的 CAS 号为 59-92-7。Levodopa 是的神经递质多巴胺的代谢前体,具有口服活性。Levodopa 能够透过血脑屏障,并在大脑中转化为多巴胺。Levodopa具有抗痛觉过敏作用。Levodopa还具有帕金森氏病的研究潜力。

同位素标记化合物

1-Amino Hydantoin-13C3
Cat.No: TMIJ-0009
Synonym:
Target:
Sulfasalazine-d4
Cat.No: TMIJ-0097
Synonym:
Target:
Taurine-d4
Cat.No: TMID-0169
Synonym:
Target:
Norfluoxetine-d5 HCl
Cat.No: T71302
Synonym:
Target:
DL-Alanine-2,3,3,3-d4
Cat.No: TMIJ-0101
Synonym:
Target:
L-Carnitine-d9
Cat.No: TMIJ-0090
Synonym:
Target:
Zearalenone-13C18
Cat.No: T35783
Synonym: Zearalenone-13C18
Target:
Maprotiline-d3 hydrochloride
Cat.No: T70960
Synonym:
Target:
Ethyl-d5-malonic Acid
Cat.No: TMID-0097
Synonym:
Target:
L-Dopa-2,5,6-d3
Cat.No: TMIJ-0312
Synonym:
Target:
TargetMol Loading
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