139
52
359
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8701 |
GRP-60367
|
Others | Others |
GRP-60367 是一种小分子狂犬病病毒进入抑制剂,对某些 RABV 株具有纳摩尔作用效果。 | |||
TP1644 |
Influenza A NP(366-374) Strain A/PR/8/35
|
||
This peptide is an H2-Db-restricted epitope from the Influenza A/PR/8/34 nucleoprotein. | |||
T7785 |
T-1105
|
Influenza Virus | Microbiology/Virology |
T-1105 是 T-705 的结构类似物,是一种广谱病毒聚合酶抑制剂,在转化为核糖核苷三磷酸代谢物后抑制 RNA 病毒的聚合酶,有抗病毒活性。 | |||
T76521 |
HCV NS4A Protein (18-40) (JT strain)
|
||
HCVNS4A Protein (18-40) (JT strain) 为HCVNS4A 肽,由第18至40个NS4A蛋白残基构成,能够增强NS3蛋白酶的催化效率。 | |||
T7700 |
Lersivirine
3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-1H-吡唑-4-基]氧基]苯腈,Lersivirine(UK 453061),UK-453061 |
HIV Protease; Reverse Transcriptase | Microbiology/Virology; Proteases/Proteasome |
Lersivirine (UK-453061) 是非核苷逆转录的抑制剂 (NNRTI),有效抑制 NNRTI 耐药病毒。它对野生型人类免疫缺陷病毒和临床相关 NNRTI 耐药菌株显示出强大的抗逆转录病毒活性。 | |||
TQ0157 |
EIPA
L593754,MH 12-43 |
Sodium Channel; TRP/TRPV Channel | Membrane transporter/Ion channel |
EIPA (L593754) 是一种有效的TRPP3 channel 抑制剂,IC50为 10.5 μM。EIPA 对Na+/H+交换 (NHE) 和巨噬细胞也有抑制作用。 | |||
T9231 |
Mbx2329
|
Antiviral | Immunology/Inflammation |
MBX2329 是一种流感病毒抑制剂,能特异性地抑制血凝素介导的病毒进入,HIV/HA(H5) 的 IC90值为8.6 μM。它能够有效地抑制多种甲型流感病毒。 | |||
T11888 |
LtaS-IN-1
|
Others; Antibacterial | Microbiology/Virology; Others |
LtaS-IN-1 是多药耐药粪肠球菌中脂磷壁酸合成的有效抑制剂,可改变细胞壁形态。 LtaS-IN-1 对抗肠球菌属 28 菌株,MIC 值从 0.5 μg/mL 到 64 μg/mL 不等。 LtaS-IN-1 抑制菌株 E1630 和 E1590,MIC 值为 0.5 μg/mL。 | |||
TQ0174 |
Mavorixafor
AMD-070 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Mavorixafor (AMD-070) 是一种有效的特异性 CXCR4 拮抗剂,对 CXCR4 125I-SDF 结合的 IC50 值为 13 nM。 Mavorixafor 在 MT-4 细胞 (IC50 = 1 nM) 和 PBMC (IC50 = 9 nM) 中抑制 T-tropic HIV-1 (NL4.3 株) 的复制。 | |||
T40421 |
4,5-Dichlorocatechol
|
Others | Others |
4,5-Dichlorocatechol 是广谱的pseudomonas chlororaphisRW71 氯邻苯二酚 1,2-二加氧酶的底物。对于Pseudomonas putidaAC27 菌株双加氧酶和AcidovoraxPS14 菌株双加氧酶的Ki 都为 30 nM。 | |||
T67912 |
PA3552-IN-1
|
Others | Others |
PA3552-IN-1 是一种抗生素佐剂, 可以降低 PA3552 的表达,恢复 MDR 铜绿假单胞菌 DK2 菌株对 Polymyxin B 的敏感性。 | |||
T67827 |
Urease Inhibitor 07
|
Others | Others |
Urease Inhibitor 07 是一种异取代金属蛋白酶抑制剂 , 对结核分枝杆菌H37Rv 菌株的潜在活性。 | |||
T3642 |
TBA-354
TBA 354 |
Antibacterial; Antibiotic | Microbiology/Virology |
TBA-354 有抗结核作用,对结核分枝杆菌 H37Rv 菌株具有活性。 | |||
T1400L |
Demeclocycline
Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol |
Antibacterial | Microbiology/Virology |
Demeclocycline (Declostatin) 是一种四环素类抗生素,产自金霉素链霉菌(Streptomyces aureofaciens)菌株。Demeclocycline 具有抗菌活性,能抑制血管加压素对肾小管的作用,从而导致利尿。Demeclocycline 可用诱导尿崩症和急性肾衰竭。 | |||
T15409 |
GNF179
|
Parasite | Microbiology/Virology |
GNF179 是8,8-二甲基 IP 类似物。 它表现出对多药耐药菌株 W2 的效力,具有良好的体外代谢稳定性和体内口服生物相容性。 | |||
T67833 |
HIV-1 inhibitor-54
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
HIV-1 inhibitor-54 是一种有效的 HIV-1 抑制剂,在 MT-4 细胞中对 WT HIV-1 (菌株 IIIB) x 显示出抗 HIV 活性(EC50 : 32 nM)。HIV-1 inhibitor-54 可用于研究病毒感染。 | |||
T7338L |
DHBP
紫外线吸收剂,Benzoresorcinol |
Others | Others |
DHBP (Benzoresorcinol) 是一种 WalKR TCS 激活剂。它通过靶向行走和选择性地促进纽曼野生型菌株的溶葡萄球菌素诱导的裂解活性起作用。 | |||
T21900 |
ML-336
(E)-2-((1,4-二甲基哌嗪-2-亚基)氨基)-5-硝基-N-苯基苯甲酰胺 |
Others | Others |
ML-336 是一种喹唑啉酮类的委内瑞拉马脑炎病毒 (VEEV) 抑制剂,其VEEV TC-83 CPE(IC50:32 nM)、VEEV V3526 CPE(IC50:20 nM)、VEEV 野生型 CPE (IC50:42 nM),有效抑制 VEEV 诱导的三种病毒株 (V3526、TC-83和野生型) 细胞病变效应。 | |||
T10903 |
CWHM-1552
|
Parasite | Microbiology/Virology |
CWHM-1552 是一种有效的恶性疟原虫抑制剂。 对于 3D7 和 Dd2 菌株,IC50 分别为 51 nM 和 53 nM。 | |||
T5997 |
TBAJ-587
|
Antibacterial; Antibiotic | Microbiology/Virology |
TBAJ-587 是一种抗结核药物,在 MABA 和 LORA 试验中抑制 M.tb 菌株 H37Rv 的生长,MIC90 分别为 0.006 和 <0.02 µg/mL。它对 M. tuberculosis 具有更有效的活性,并且在 TB 动物模型中具有更好的功效。 | |||
T73721 |
Phleomycin D1
PLM D1,PLM-D1 |
Antibacterial; Antibiotic | Microbiology/Virology |
Phleomycin D1 (PLM D1) 是一种由Streptomyces verticillus(轮枝链霉菌)的突变株产生的一种糖肽抗生素,具有抗菌活性,可破坏细菌双螺旋结构的完整性。Phleomycin D1 可用于筛选携带Sh ble基因的转染细胞。 | |||
T77948 |
Tri-GalNAc-DBCO
|
PROTACs | PROTAC |
Tri-GalNAc-DBCO是一种PIP-GalNAc 偶联物,通过无铜菌株促进的叠氮化物-炔烃环加成与非特异性标记抗体上的叠氮化物偶联,可结合ASGPR以驱动蛋白质下调和靶向蛋白质降解的化合物。 | |||
T16500 |
PF-3450074
PF-74 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
PF-3450074 (PF-74)是 HIV-1 衣壳蛋白的特异性抑制剂,可广谱抑制 HIV 分离株。它在 HIV-1 感染的早期阶段起作用,通过与 CPSF6 和 NUP153 的结合直接竞争来抑制病毒复制,并阻断病毒生命周期的脱膜,组装和逆转录步骤。 | |||
T4531 |
GSK2200150A
|
Antibacterial | Microbiology/Virology |
GSK2200150A 是一种通过高通量筛选活动确定的抗结核剂,对 H37Rv 的 MIC 是 0.38 μM。 | |||
T37739 |
N-decanoyl-L-Homoserine lactone
C10-HSL,N-decanoyl-L-Homoserine lactone |
Reactive Oxygen Species; Antibacterial | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高,增加丝裂原激活蛋白激酶 6 (MPK6) 的活性,并促使一氧化氮 (NO) 的产生。 | |||
T39693 |
Polyketide synthase 13-IN-3
|
Others | Others |
Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv. | |||
T10296 |
Mavorixafor trihydrochloride
AMD-070 trihydrochloride |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM). | |||
T12084 |
MMV008138
|
Others | Others |
MMV008138 inhibits the growth of P. falciparum Dd2 strain (IC50 of 250 nM). | |||
T25438 |
FR 900137
FR900137,FR-900137,Antibiotic FR 900137 |
Others | Others |
FR 900137 is a new antibiotic agent from a new strain of Streptomyces. | |||
T26411 |
A 269A
A269A |
Others | Others |
A 269A is an antibiotic isolated from broth of Streptomyces sp., strain. | |||
T31251 |
Deacetylsclerotiorin
Deacetylsclerotiorin, (+)-,(+)-Deacetylsclerotiorin |
Others | Others |
Deacetylsclerotiorin is a chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550. | |||
T26501 |
AB 3217-C
AB3217-C,AB-3217-C |
Others | Others |
AB 3217-C is an anti-mite substance isolated from streptomycete strain. | |||
T31252 |
Deacetylsclerotiorin, (-)-
(-)-Deacetylsclerotiorin |
Others | Others |
deacetylsclerotiorin is a new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550. | |||
T32949 |
Luminamicin
|
Others | Others |
Luminamicin is active against anaerobic bacteria, especially Clostridium sp.; isolated from actinomycete strain OMR-59. | |||
T34643 |
Simaomicin alpha
L D42067alpha,LL D42067alpha,LL-D42067alpha |
Others | Others |
Simaomicin alpha is an actinomycete metabolite isolated from an actinomycete strain. | |||
T34810 |
Terpentecin
MF 730N6,Antibiotic MF 730N6 |
Others | Others |
Terpentecin is isolated from strain MF730-N6 and is active against leukemia L-1210 and Ehrlich ascites carcinoma. | |||
T24992 |
A-130A
Antibiotic A 130A,A 130A,Antibiotic Ro 21 6150,Lenoremycin |
Others | Others |
A-130A is a polycyclic polyether compound belonging to the nigericin group of antibiotics generated by Streptomyces hygroscopicus strain. | |||
T26418 |
A 51493A
A-51493A,A51493A |
Others | Others |
A51493A is a novel antibiotic in the class of anthracyclinone, it is produced by a strain of Streptomyces humifer. | |||
T69981 |
CRM-51005
|
Others | Others |
CRM-51005 is a new phospholipase C inhibitor produced by unidentified fungal strain MT51005 | |||
T71792 |
Quipazine maleate
|
Others | Others |
Quipazine maleate is a selective 5-HT receptor agonist that promotes the proliferation and apoptosis of human hepatocyte strain of L-02 strain and could also exert an excitatory effect on raphe neurons via stimulation of 5-HT2A receptors. Like quipazine, quipazine derivatives produce contracture of smooth muscle organs and bronchospasm. | |||
T70034 |
Dehatrine
|
Others | Others |
Dehatrine is from an Indonesian medical plant Beilschmiedia madang; a bisbibenzylisoquinoline alkaloid; inhibits growth of cultured Plasmodium falciparum K1 strain. | |||
T26176 |
Saphenamycin
Racemic ssaphenamycin |
Others | Others |
Saphenamycin is an antibiotic from a strain of Streptomyces. | |||
T60324 |
Fungicide4
|
Others | Others |
Fungicide4 对P. infestans 菌株显示出高活性。 | |||
T26500 |
AB 3217-B
AB-3217-B,AB3217-B |
Others | Others |
AB 3217-B is an anti-mite substance isolated from streptomycete strain. | |||
T36075 |
Cholic Acid anilide
|
Others | Others |
Cholic acid anilide is a synthetic bile acid and derivative of cholic acid that inhibits the germination of C. difficile strain R20291 spores in vitro (IC50 = 1.8 μM).1 |1. Sharma, S.K., Yip, C., Esposito, E.X., et al. The design, synthesis, and characterizations of spore germination inhibitors effective against an epidemic strain of Clostridium difficile. J. Med. Chem. 61(15), 6759-6778 (2018). | |||
T72717 |
Anti-IAV agent 1
|
Others | Others |
Anti-IAV agent 1-1a) 是一种口服抗甲型流感病毒(IAV)剂,对IAV H1N1及Oseltamivir抗性IAV H1N1的IC50值分别是0.03μM与0.06μM。 | |||
T28756 |
Septamycin
A 28695A,A28695A,A-28695A |
Others | Others |
Septamycin is a polycyclic, polyether, monocarboxylic acid antibiotic. Septamycin is isolated from strain of Streptomyces albus. | |||
T26406 |
A 204
Antibiotic A-204,Antibiotic A204,A-204,Antibiotic A 204,A204 |
Others | Others |
A 204 is a polycyclic polyether monocarboxylic acid antibiotic isolated from fermentation of strain of Streptomyces albus. | |||
T11445 |
GNF179 (Metabolite)
GNF179 Metabolite |
Others | Others |
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral bioavailability. | |||
T80395 |
Abaecin
|
||
Abaecin是一种具有针对Apidaecin抗性黄单胞菌菌株的特异活性的抗菌肽。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2027 |
Oxysanguinarine
8-Oxosanguinarine,氧化血根碱,Hydroxysanguinarine |
Parasite | Microbiology/Virology |
Oxysanguinarine (Hydroxysanguinarine) 是一种来自Meconopsis simplicifolia 的小檗生物碱,具有抗疟和抗血小板聚集活性,对登革热病毒具有潜在的抑制作用。 | |||
T1100 |
Polymyxin B Sulfate
Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX |
Antibacterial; Antibiotic | Microbiology/Virology |
Polymyxin B Sulfate (Poly-RX) 是一个阳离子型表面活性剂抗生素剂,能够提高细胞膜的渗透性。 | |||
T11288 |
Filipin III
|
Antifungal | Microbiology/Virology |
Filipin III 是 从菌株KPE18H 中提取得到,具有显著的抗真菌活性。 | |||
T6402 |
Azomycin
2-Nitroimidazole,2-硝基咪唑,Ro 05-9129,Amicin |
Antibacterial; Antibiotic | Microbiology/Virology |
Azomycin (Ro 05-9129) 是一种可抑制有氧革兰氏阳性菌和革兰氏阴性菌的生长的抗生素。 | |||
T9790 |
Lactoferrin
Lactoferrin (Bovine) |
Endogenous Metabolite | Metabolism |
Lactoferrin 由哺乳动物分泌,具有广泛的生物学作用,包括提高应用良好的益生菌菌株的耐寒性。 | |||
TN5503 |
Linaroside
|
Antibacterial | Microbiology/Virology |
Linaroside 在 6.25 microg mL(-1) 浓度下对结核分枝杆菌、菌株 H(37)Rv 的抗分枝杆菌活性表现出 30%的抑制作用。 | |||
TCS2070 |
Homogentisic acid
高龙胆酸,2,5-dihydroxyphenylacetic acid,Homogentisinic Acid,Melanic acid |
Antioxidant; Endogenous Metabolite | Metabolism; oxidation-reduction |
Homogentisic acid (2,5-dihydroxyphenylacetic acid) 是一种尿液和血清代谢物中的特定代谢物,可用于尿黑酸尿症的诊断。 | |||
T12796 |
S-Dihydrodaidzein
S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one |
Others | Others |
S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) 是一种 dihydrodaidzein 的 (S) 型对映体。其中 dihydrodaidzein 是一种可食用性植物雌激素。 | |||
T5S2357 |
Acetylcorynoline
(+)-Corynoline Acetate,O-Acetylcorynoline,乙酰紫堇灵 |
Antifungal | Microbiology/Virology |
Acetylcorynoline (O-Acetylcorynoline) 是提取自 Corydalis bungeana 中的一种主要生物碱成分,具有抗炎活性。 | |||
T2762 |
Kasugamycin hydrochloride
Kasumin,盐酸春雷霉素 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Kasugamycin hydrochloride (Kasumin) 是一种能结合 30s 和 70s 核糖体,但不能结合 50s 亚基的抗生素。它模拟 mRNA 核苷酸以破坏 tRNA 结合并抑制经典翻译起始。 | |||
T4964 |
steviolbioside
CCRIS-6025,菊双糖甙,甜菊双糖苷 |
Others | Others |
Steviolbioside (CCRIS-6025) 是一种存在于甜菊叶中的罕见甜味剂。它对几种人类癌细胞有抑制作用,对乳腺癌具有潜在的研究价值。 | |||
T3629 |
Gamithromycin
ML-1709460,加米霉素 |
Antibacterial; Antibiotic | Microbiology/Virology |
Gamithromycin (ML-1709460) 是一种可抑制 MmmSC 菌株 B237 和 Tan8 生长的大环内酯类抗菌剂,MIC 值分别为 0.00012 和 0.00006 μg/mL。 | |||
T20879 |
Tacrolimus monohydrate
FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,他克莫司一水合物,FK 506 |
Phosphatase; Others; Antibacterial; Antibiotic; Autophagy | Autophagy; Metabolism; Microbiology/Virology; Others |
Tacrolimus monohydrate (LCP-Tacro) 是大环内酯类化合物,它与 FK506 结合蛋白 (FKBP) 结合形成复合物并抑制钙调神经磷酸酶,从而抑制 T 淋巴细胞信号转导和 IL-2 转录。具有强免疫抑制特性。 | |||
T37341 |
N-Acetyltyramine
|
Antibacterial | Microbiology/Virology |
N-Acetyltyramine 是一种群体感应抑制剂,由溶藻弧菌 M3-10 产生。N-Acetyltyramine 可以抑制C. violaceumATCC 12472 的群体感应。它可以逆转阿霉素耐药白血病 P388 细胞的耐药性。 | |||
T2S2362 |
Dehydrocorydaline nitrate
去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱 |
BCL; Others; PARP; p38 MAPK; Caspase; Parasite; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Others; Proteases/Proteasome |
Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达,激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌、抗疟疾等功效。 | |||
T12299 |
Oligomycin C
|
Others | Others |
Oligomycin C is an antifungal agent isolated from Streptomyces strain. | |||
T29091 |
Valilactone
(-)-Valilactone |
Others | Others |
Valilactone is a fatty acid synthase inhibitor, which is produced by a cultured strain of soil actinomycetes. | |||
TN6447 |
Cyclo(Leu-Val)
|
||
Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain. | |||
T3831 |
Licoricone
|
Antifection | Microbiology/Virology |
Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. | |||
T38235 |
16-Keto Aspergillimide
|
Others | Others |
16-Keto Aspergillimide (SB202327) is a novel anthelmintic compound derived from the Aspergillus strain IMI 337664. | |||
TN3583 |
Canophyllal
|
Antifection | Microbiology/Virology |
Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs. | |||
TN4717 | Oplopanone | Antifection | Microbiology/Virology |
Oplopanone exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strain. | |||
T17198 |
UCN-02
7-epi-Hydroxystaurosporine |
Others | Others |
UCN-02 is a selective protein kinase C inhibitor produced by Streptomyces strain N-12 (IC50s: 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively). | |||
T83155 |
Agonodepside B
|
||
Agonodepside B, 分离自非孢子丝状真菌F7524,是一种化合物。 | |||
T82706 |
Clonostachydiol
|
||
Clonostachydiol为源于真菌Clonostachys cylindrospora(菌株FH-A 6607)的大分子内酯类驱虫药。 | |||
TN3608 |
Catalpin
|
Others | Others |
Catalpin exhibited mutagenic activity towards Salmonella typhimurium strain TA100 in the presence and absence of rat liver homogenate (S9) mix in Ames' test. | |||
T81318 |
R-30-Hydroxygambogic acid
|
||
R-30-Hydroxygambogic acid是从藤黄提取的一种聚戊烯酰黄酮外聚体,对K562/R和K562/S两种人白血病细胞系的IC50分别为2.89 μM和1.27 μM。该化合物适用于癌症研究领域。 | |||
T81906 |
Lucidenic acid K
|
||
Lucidenic acid K,一种灵芝酸,自G. lucidum子实体(YK-02)菌株中分离得到。 | |||
T80001 |
Majoranaquinone
|
Antibiotic | Microbiology/Virology |
Majoranaquinone对4种Staphylococcus菌株、1种Moraxella菌株和1种Enterococcus菌株显示出良好的抑菌作用。此外,Majoranaquinone在E.coli ATCC 25922菌株中表现出显著的外排泵抑制活性,并能有效抑制E.coli ATCC 25922和E.coli K-12 AG100的生物膜形成。 | |||
TN2311 |
Wulignan A1
五脂素 A1 |
Antifection | Microbiology/Virology |
Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities. | |||
T83245 |
7-Desmethylmicrocystin-LR
|
||
7-Desmethylmicrocystin-LR为有毒七肽类化合物,可自无菌铜绿微囊藻菌株(K-139)中提取。 | |||
T28379 |
PF-1163B
PF1163B,(-)-PF1163B,PF 1163B |
Others | Others |
PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotox | |||
TMA2418 |
1-Methoxyphaseollidin
|
PAFR; Antifection | GPCR/G Protein; Microbiology/Virology |
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity against KB and L1210 cells. 1-Methoxyphaseollidin also shows inhibition of lysoPAF acetyltransferase activity. | |||
TN3907 |
Pinosylvin monomethyl ether
(E)-3-Hydroxy-5-methoxystilbene |
Antifection | Microbiology/Virology |
(E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacillusanthracis (Sterne strain), among | |||
TN3403 |
Djalonensone
交链孢霉甲基醚,Alternariol monomethyl ether |
Immunology/Inflammation related | Immunology/Inflammation |
Djalonensone (Alternariol monomethyl ether) 具有强大的 DPPH 自由基清除作用。 | |||
TN3461 |
Asebotin
|
Influenza Virus | Microbiology/Virology |
Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit the proliferation of murine B cells. | |||
TN4776 |
Physalin D
|
TNF; Antifection | Apoptosis; Microbiology/Virology |
Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. Physalin D displays considerable cytotoxicity against several cancer cell lines. It | |||
T75568 |
Z-Antiepilepsirine
|
Others | Others |
Z-Antiepilepsirine 是一种酰胺生物碱,存在于 Piper capense L.f 中。Z-Antiepilepsirine 显示抗疟原虫活性,对 PlasmodiumfalciparumW2 菌株的 IC50值为 27 µM。 | |||
T83584 |
(±)-Lavandulol
|
||
(±)-Lavandulol为一不对称的单萜醇,能由米根霉(Rhizopus oryzae)真菌转化为其对应氧化代谢产物。 | |||
T75638 |
Himastatin
|
Others | Others |
Himastatin 是一种具有抗肿瘤活性的抗生素,由S. hygroscopicus sp 菌株产生。Himastatin 是一种二聚环六肽,含有哌嗪酸和一个独特的芳香族中心。 | |||
TN4388 |
Kielcorin
|
Antifection | Microbiology/Virology |
Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils (IC (50) = 965.21 ± 65.80 uM). trans-Kielcorin has hepatoprotective activity, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes. | |||
T75507 |
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone
|
Others | Others |
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone 对幽门螺杆菌菌株 51 表现出有效的抗菌活性,MIC50 值和 MIC90 值分别为 22 µM 和 50 µM。该化合物展现了在研究胃及十二指肠溃疡方面的潜力。 | |||
T75523 |
Wychimicin A
|
Others | Others |
Wychimicin A 是一种螺旋藻酸聚酮,可从罕见的放线菌 Actinocrispum wychmicini 菌株 MI503-AF4 中分离得到。Wychimicin A 具有强抗菌活性,显著抑制耐甲氧西林的金黄色葡萄球菌Staphylococcus. aureus(IC50=0.125-0.5 μg/mL) 和 肠球菌Enterococcus. Faecalis/faecium(IC50=0.25 μg/mL)。 | |||
T75522 |
Wychimicin C
|
Others | Others |
Wychimicin C为源自罕见放线菌Actinocrispum wychmicini菌株MI503-AF4的螺旋藻酸聚酮类化合物。此化合物展现出卓越的抗菌效果,尤其对耐甲氧西林的Staphylococcus. aureus(IC50=0.125-0.5 μg/mL)和Enterococcus. Faecalis/faecium(IC50=0.125-0.25 μg/mL)展现显著的抑制活性。 | |||
TN4113 |
Garcinone E
|
Antifection | Microbiology/Virology |
Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer. | |||
T38015 |
Herquline A
|
Others | Others |
Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively). | |||
TN4449 |
Longistylin C
|
Antifection | Microbiology/Virology |
Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. Longistylin A and longistylin C, and betulinic acid show a moderately high in vitro activity against the chloroquine | |||
T81958 |
Lacto-N-neodifucohexaose II
LNnDFH II |
||
Lacto-N-neodifucohexaose II(Compd 9),一种关键的人乳四糖衍生物,为点击化学反应试剂。该化合物含 Azide 基团,适用于铜催化叠氮-炔环加成反应(CuAAc),与含 Alkyne 基团的分子反应。同时,它也能与含 DBCO 或 BCN 基团的分子,进行菌株促进的炔-叠氮环加成反应(SPAAC)。 | |||
T35758 |
Butyrolactone V
|
Others | Others |
Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM).2,1 Butyrolactone V (227 and 454.1 μM) is also active against adult S. mansoni worms.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS radicals with IC50 values of 20.7 and 3.7 μM, respectively, in cell-free assays.3 Butyrolactone V also... | |||
T35751 |
Violacein
|
Others | Others |
Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserine lactone , a property that has been modified to create a strain of C. violaceum used in detecting quorum-sensing molecules.[3] Violacein is active against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.8 and 1.6 µM, respectively). It is also active aga... | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00054 |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)
Macaca fascicularis Cytωlovirus (CyCMV) (strain OT-... |
CyCMV | HEK293 Cells |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 102.5 kDa and the accession number is E7DB34. | |||
TMPY-06572 |
Vaccinia virus (VACV) (strain Copenhagen) Protein B5 (His)
|
VACV | HEK293 Cells |
Vaccinia virus (VACV) (strain Copenhagen) Protein B5 (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.53 kDa and the accession number is P21115. | |||
TMPY-04870 |
Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His)
|
ZIKV | HEK293 Cells |
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates signalling of the innate immune system, has possible damages to platelets and endothelial cells through anti-NS1 antibodies. | |||
TMPY-01552 |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0. | |||
TMPY-04865 |
Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His)
|
CHIKV | Baculovirus Insect Cells |
Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A5Y7Y5. | |||
TMPY-04892 |
Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (His)
|
ZIKV | Baculovirus Insect Cells |
Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 45.5 kDa and the accession number is ALU33341.1. | |||
TMPY-04192 |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591. | |||
TMPY-04903 |
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His)
DENV-NS1 |
DENV | HEK293 Cells |
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is AAA99437.1. | |||
TMPY-00052 |
Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His)
DENV-NS1 |
DENV | HEK293 Cells |
Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is AAC59275.1. | |||
TMPY-03236 |
Human respiratory syncytial virus (RSV) Fusion protein/RSV-F (Strain RSS-2) Protein (His)
F Protein,HRSVgp8 |
RSV | Baculovirus Insect Cells |
Human respiratory syncytial virus (RSV) Fusion protein/RSV-F (Strain RSS-2) Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is P11209. | |||
TMPY-00065 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His)
Matrix protein VP40 |
EBOV | E. coli |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.4 kDa and the accession number is B8XCM9. | |||
TMPY-05824 |
Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His)
E Protein |
DENV | HEK293 Cells |
Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.79 kDa and the accession number is AAA99437.1. | |||
TMPY-06338 |
Human respiratory syncytial virus (RSV) (strain A2, strain Long) Nucleoprotein Protein (His)
|
RSV | E. coli |
Human respiratory syncytial virus (RSV) (strain A2, strain Long) Nucleoprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 44.28 kDa and the accession number is P03418. | |||
TMPY-04689 |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His)
E Protein, DENV |
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAC59274.1. | |||
TMPH-03693 |
VSIV (strain Glasgow) Matrix Protein (His)
M,Matrix protein |
VSIV | E. coli |
VSIV (strain Glasgow) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.8 kDa and the accession number is P04876. | |||
TMPH-03690 |
VEEV (strain 3880) P1234 Protein (His)
Polyprotein P1234,Non-structural polyprotein |
VEEV | E. coli |
VEEV (strain 3880) P1234 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 55.7 kDa and the accession number is P36327. | |||
TMPH-03656 |
Vaccinia virus (strain Copenhagen) TopIB Protein (His)
Late protein H6,DNA topoisomerase 1B,DNA topoisomerase I,OPG... |
VACV | E. coli |
Vaccinia virus (strain Copenhagen) TopIB Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.7 kDa and the accession number is P68697. | |||
TMPH-03698 |
VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc)
Phosphoprotein,P,Protein M1 |
VSIV | E. coli |
Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template. May act as a chaperone for newly synthesized free N protein, so-called N(0). Plays a role in virion assembly. VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is P04879. | |||
TMPH-00149 |
IBV (strain D274) Spike glycoprotein (His)
S,E2,Spike glycoprotein,Peplomer protein |
IBV | E. coli |
IBV (strain D274) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 27.2 kDa and the accession number is P12722. | |||
TMPH-00150 |
IBV (strain D3896) Spike glycoprotein (His)
S,E2,Spike glycoprotein,Peplomer protein |
IBV | E. coli |
IBV (strain D3896) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 25.8 kDa and the accession number is P17662. | |||
TMPH-03694 |
VSIV (strain Glasgow) Matrix Protein (His & Myc)
Matrix protein,M |
VSIV | Baculovirus Insect Cells |
VSIV (strain Glasgow) Matrix Protein (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 30.7 kDa and the accession number is P04876. | |||
TMPH-00252 |
Bovine coronavirus (strain Mebus) Protein I (His)
IORF,Protein in nucleocapsid ORF,N,I,Accessory protein N2,N ... |
BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain Mebus) Protein I (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 25.5 kDa and the accession number is P10525. | |||
TMPH-00032 |
ASFV (strain Ba71V) p17 Protein (His)
Ba71V-107,Minor capsid protein p17,D117L |
ASFV | E. coli |
Essential for the correct processing of both structural polyproteins and for the maturation of viral precursor membranes at the viral factories. ASFV (strain Ba71V) p17 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is Q89424. | |||
TMPH-00261 |
Bovine coronavirus (strain vaccine) Spike glycoprotein (His)
Spike glycoprotein,E2,S glycoprotein,S,Peplomer protein |
BCoV | E. coli |
Bovine coronavirus (strain vaccine) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 24.6 kDa and the accession number is P25194. | |||
TMPH-03229 |
Rabies virus (RABV) (strain PM) Phosphoprotein (His)
P,Protein M1,Phosphoprotein |
RABV | E. coli |
Rabies virus (RABV) (strain PM) Phosphoprotein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.2 kDa and the accession number is P69480. | |||
TMPH-00033 |
ASFV (strain Ba71V) p30 Protein (His)
Ba71V-93,Phosphoprotein p30,p30,CP204L,Phosphoprotein p32 |
ASFV | E. coli |
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection. | |||
TMPH-00258 |
Bovine coronavirus (strain Quebec) Spike glycoprotein (His)
S,E2,Spike glycoprotein,S glycoprotein,Peplomer protein |
BCoV | P. pastoris (Yeast) |
Bovine coronavirus (strain Quebec) Spike glycoprotein (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 36.8 kDa and the accession number is P25193. | |||
TMPH-00141 |
IBV (strain D1466) Nucleoprotein/NP Protein (His)
N,Nucleoprotein,Nucleocapsid protein |
IBV | E. coli |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain D1466) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession nu... | |||
TMPH-00138 |
IBV (strain KB8523) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
IBV | HEK293 Cells |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain KB8523) Nucleoprotein/NP Protein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 47.2 kDa and the accession numb... | |||
TMPH-03665 |
Vaccinia virus (strain Copenhagen) OPG185 Protein (His)
Hemagglutinin,Protein OPG185,OPG185 |
VACV | E. coli |
Prevents cell to cell fusion by interacting with and directing the viral K2 protein on the host plasma membrane. The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation. Via its interaction with C3/VCP protein, protects the infected cell and probably also the extracellular enveloped virus from complement attack. Vaccinia virus (strain Copenhagen) OPG185 Protein (His) is expressed in E. coli expression system with ... | |||
TMPH-03667 |
Vaccinia virus (strain Copenhagen) OPG190 Protein (His)
Plaque-size/host range protein,Protein OPG190,OPG190 |
VACV | P. pastoris (Yeast) |
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracellular enveloped virions (IEV). Vaccinia virus (strain Copenhagen) OPG190 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is P21115. | |||
TMPH-00145 |
IBV (strain H52) Nucleoprotein/NP Protein (His)
Nucleocapsid protein,Nucleoprotein,N |
IBV | HEK293 Cells |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain H52) Nucleoprotein/NP Protein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 47.4 kDa and the accession number ... | |||
TMPH-00249 |
Bovine coronavirus (strain Quebec) Nucleoprotein/NP Protein (His)
N,NC,Nucleoprotein,Nucleocapsid protein,Protein N |
BCoV | E. coli |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Bovine coronavirus (strain Quebec) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 50.3 kDa and ... | |||
TMPH-00136 |
IBV (strain Beaudette CK) Nucleoprotein/NP Protein (His)
N,Nucleocapsid protein,Nucleoprotein |
IBV | HEK293 Cells |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain Beaudette CK) Nucleoprotein/NP Protein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 47.2 kDa and the accessio... | |||
TMPH-00259 |
Bovine coronavirus (strain Mebus) Spike glycoprotein (His)
S,Peplomer protein,Spike glycoprotein,E2,S glycoprotein |
BCoV | E. coli |
Bovine coronavirus (strain Mebus) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 24.7 kDa and the accession number is P15777. | |||
TMPH-03219 |
Rabies virus (RABV) (strain India) Glycoprotein (His)
Glycoprotein,G |
RABV | P. pastoris (Yeast) |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPH-00137 |
IBV (strain Arkansas 99) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
IBV | HEK293 Cells |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain Arkansas 99) Nucleoprotein/NP Protein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 47.4 kDa and the accession... | |||
TMPH-00232 |
Bovine coronavirus (strain Mebus) Hemagglutinin-esterase Protein (His)
Hemagglutinin-esterase,E3 glycoprotein,HE,HE protein |
Bovine | P. pastoris (Yeast) |
Bovine coronavirus (strain Mebus) Hemagglutinin-esterase Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 47.7 kDa and the accession number is P15776. | |||
TMPH-00153 |
IBV (strain UK/123/82) Spike glycoprotein (His)
E2,Spike glycoprotein,S,Peplomer protein |
IBV | HEK293 Cells |
IBV (strain UK/123/82) Spike glycoprotein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 27 kDa and the accession number is P30206. | |||
TMPH-00256 |
Bovine coronavirus (strain LY-138) Protein I (His)
I,N internal ORF protein,N,Accessory protein N2,Protein I,IO... |
BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain LY-138) Protein I (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 25.4 kDa and the accession number is Q9QAR7. | |||
TMPH-03660 |
Vaccinia virus (strain Lister) OPG190 Protein (His)
OPG190,Protein OPG190,Plaque-size/host range protein |
VACV | E. coli |
Regulation of plaque size and host range. Vaccinia virus (strain Lister) OPG190 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is P24083. | |||
TMPH-02395 |
Lassa virus (strain GA391) GPC Protein (His)
Pre-glycoprotein polyprotein GP complex,GPC |
LASV | E. coli |
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation clea... | |||
TMPH-02981 |
Mumps virus (strain RW) Hemagglutinin-neuraminidase Protein (His)
HN,Hemagglutinin-neuraminidase |
MuV | E. coli |
Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.; Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins. Mumps virus (strain RW) Hemagglutinin-neuraminidase Protein (His) is expressed in E. coli expression system with N-10... | |||
TMPH-03734 |
Zaire ebolavirus (strain Mayinga-76) L Protein (His)
Transcriptase,L,RNA-directed RNA polymerase L,Large structur... |
ZEBOV | E. coli |
Zaire ebolavirus (strain Mayinga-76) L Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is Q05318. | |||
TMPH-03220 |
Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)
Glycoprotein,G |
RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPH-00148 |
IBV (strain M41) Spike glycoprotein (His)
S,E2,Spike glycoprotein,Peplomer protein |
IBV | E. coli |
IBV (strain M41) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 26.8 kDa and the accession number is P12651. | |||
TMPH-03680 |
Vaccinia virus (strain LC16m8) B5 Protein (His)
PS/HR,Protein B5,Truncated plaque-size/host range protein |
VACV | P. pastoris (Yeast) |
Regulation of plaque size and host range. In this strain the truncated ps/hr protein is probably not functional. Vaccinia virus (strain LC16m8) B5 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.6 kDa and the accession number is P24284. | |||
TMPH-03697 |
VSIV (strain Glasgow) Nucleoprotein/NP Protein (His & Myc)
N,Nucleoprotein,Nucleocapsid protein |
VSIV | E. coli |
VSIV (strain Glasgow) Nucleoprotein/NP Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.9 kDa and the accession number is P11212. | |||
TMPH-00248 |
Bovine coronavirus (strain Mebus) Nucleoprotein/NP Protein (His)
Nucleocapsid protein,NC,Nucleoprotein,Protein N,N |
BCoV | E. coli |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Bovine coronavirus (strain Mebus) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 55.3 kDa and t... | |||
TMPH-00257 |
Bovine coronavirus (strain LY-138) Spike glycoprotein (His)
S,Peplomer protein,E2,S glycoprotein,Spike glycoprotein |
BCoV | P. pastoris (Yeast) |
Bovine coronavirus (strain LY-138) Spike glycoprotein (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 36.6 kDa and the accession number is P25192. | |||
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