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PknB-IN-1 (Compound 2) is an inhibitor of protein kinase B (PknB) with a concentration causing 50% inhibition (IC50) of 14.4 μM. This compound demonstrates anti-mycobacterial activity by effectively suppressing the growth of M. tuberculosis H37Rv strain, with a minimum inhibitory concentration (MIC) of 6.2 μg/mL [1].
PknB-IN-1 (Compound 2) is an inhibitor of protein kinase B (PknB) with a concentration causing 50% inhibition (IC50) of 14.4 μM. This compound demonstrates anti-mycobacterial activity by effectively suppressing the growth of M. tuberculosis H37Rv strain, with a minimum inhibitory concentration (MIC) of 6.2 μg/mL [1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | |
50 mg | ¥ 13,800 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | PknB-IN-1 (Compound 2) is an inhibitor of protein kinase B (PknB) with a concentration causing 50% inhibition (IC50) of 14.4 μM. This compound demonstrates anti-mycobacterial activity by effectively suppressing the growth of M. tuberculosis H37Rv strain, with a minimum inhibitory concentration (MIC) of 6.2 μg/mL [1]. |
体外活性 | PknB-IN-1 (0-100 μM; 60 min) can inhibit M. tuberculosis PknB activity [1]. Cell Viability Assay [1] Cell Line: M. tuberculosis Concentration: 0-100 μM Incubation Time: 60 min Result: Exhibited M. tuberculosis PknB inhibition activity (IC 50 =7.3 μM). |
分子量 | 390.52 |
分子式 | C25H30N2O2 |
CAS No. | 1447917-39-6 |
存储 | Shipping with blue ice. |
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