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Search Results for " division "

Targets Recommended: Apoptosis Mitophagy Dynamin Autophagy

87

抑制剂 & 化合物

20

天然产物

4

化合物库

56

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L1380	转录因子库		695 compounds
	695 种转录因子靶向、结构新颖的化合物；
L1110	微管靶向化合物库		142 compounds
	142 种靶向微管的分子集合，用于高通量筛选和高内涵筛选；
L8100	细胞周期化合物库		677 compounds
	677 种细胞周期相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L3700	JAK-STAT 化合物库		252 compounds
	252 个 JAK/STAT 靶点相关的小分子化合物的独特集合，用于高通量、高内涵筛选；

化合物库

转录因子库

Cat.No: L1380

Compounds: 695

微管靶向化合物库

Cat.No: L1110

Compounds: 142

细胞周期化合物库

Cat.No: L8100

Compounds: 677

JAK-STAT 化合物库

Cat.No: L3700

Compounds: 252

Cat. No.	Product Name	Target	Signaling Pathways
T1907	Mdivi-1 Mitochondrial division inhibitor 1	Apoptosis; Mitophagy; Dynamin; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling
	Mdivi-1 (Mitochondrial division inhibitor 1) 是一种线粒体分裂抑制剂，抑制 DRP1 和 Dynamin I (IC50=1-10 μM)。Mdivi-1 可以抑制线粒体自噬。
T8513	Spastazoline	Others	Others
	Spastazoline 是spastin(一种微管切断AAA 蛋白) 的选择性抑制剂，对人 spastin 的IC50值为 99 nM。它不能影响重组人 VPS4 的 ATPase 活性。
T12642L	Simurosertib TAK-931	CDK	Cell Cycle/Checkpoint
	Simurosertib (TAK-931) 是一种选择性和 ATP 竞争性细胞分裂周期 7 激酶抑制剂，具有抗癌活性，IC50值小于 0.3 nM。
T6393	ARQ 621	Kinesin	Cytoskeletal Signaling
	ARQ 621 是一种变构和选择性 Eg5 有丝分裂运动蛋白抑制剂，具有抗肿瘤活性。
T21970	ML-097	GTPase	GPCR/G Protein
	ML-097 是 Ras 相关 GTP 酶的泛激活剂。
T21678	3MB-PP1	PLK	Cell Cycle/Checkpoint
	3MB-PP1是嘌呤类似物，是一种 Polo 样激酶 1 (Plk1) 抑制剂。在表达类似物敏感的 Plk1 等位基因的细胞中，3MB-PP1 通过靶向 Plk1 阻断有丝分裂进程和细胞分裂。3MB-PP1 特异性抑制类似物敏感的 Ssn3 (Cdk8)。3MB-PP1 抑制 Leu93 突变 Zipper-interacting protein kinase(Leu93-ZIPK)，IC50为2 μM。3MB-PP1 可用于细胞分裂和白色念珠菌 (Candida albicans) 菌丝形成的研究。
T0849	Pyrimethamine Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶	DHFR; Antifolate; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Pyrimethamine (Pirimecidan) 是一种二氢叶酸还原酶的竞争性抑制剂，用作抗疟药。
T22991	ML-099	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	ML-099 是广谱的 Ras 相关GTPases 激活剂，对Rac1、cell division cycle 42、Ras、Rab7和Rab-2A 均有激活作用。
T8586	cicloprofen	Others	Others
	cicloprofen 是细胞分裂周期 7 相关蛋白激酶（人）抑制剂。
T15141	DM4 Ravtansine,美登素 DM4	Others; Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling; Others
	DM4 (Ravtansine)可用于制备抗体药物偶联物，是抗微管蛋白剂。它抑制细胞分裂。
T12642	(R)-Simurosertib (R)-TAK-931	CDK	Cell Cycle/Checkpoint
	(R)-Simurosertib ((R)-TAK-931) 是具有 ATP 竞争作用的细胞分裂周期 7 (CDC7) 激酶的抑制剂。
T3256	MMAF 一甲基澳瑞他汀 F,MonoMethyl auristatin F	Others; Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling; Others
	MMAF (MonoMethyl auristatin F) 是一种抗有丝分裂剂，通过阻断微管蛋白的聚合来抑制细胞分裂，用作抗肿瘤药物和抗体偶联药物的细胞毒性成分。
T6897	Monomethyl auristatin E 一甲基澳瑞他汀E,Vedotin,MMAE	Apoptosis; Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Cytoskeletal Signaling
	Monomethyl auristatin E (MMAE) 是海兔毒素 10 的合成衍生物，是一种抗有丝分裂剂，通过阻断微管蛋白的聚合来抑制细胞分裂，并且还具有抑制抗体-药物偶联物的活性。
T3352	XL413	cholecystokinin; Casein Kinase; Pim; CDK	Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; JAK/STAT signaling; Metabolism; Stem Cells
	XL413 是一种口服生物可利用的细胞分裂周期 7 同源物 (CDC7) 激酶抑制剂，具有潜在的抗肿瘤活性，IC50值为 3.4 nM。它对 pMCM 的 EC50值为 118 nM，对 CK2 和 PIM1 的 IC50值分别为 215 和 42 nM。
T1060	Flumequine Flumigal,氟甲喹,R-802	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Flumequine (R-802) 是一种喹诺酮类抗生素，对革兰氏阳性菌和革兰氏阴性菌均有效。它是拓扑异构酶 II 抑制剂，抑制细胞分裂，IC50值为 15 μM (3.92 μg/mL)。
T14348	Auristatin E	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	Auristatin E 通过阻断微管蛋白的聚合来抑制细胞分裂。它是一种细胞毒性微管蛋白修饰剂，具有强效和选择性抗肿瘤活性。它是一种 MMAE 类似物，是抗体-药物偶联物中的细胞毒素。
T25214	CCR-11 CCR11,CCR 11	Antibiotic	Microbiology/Virology
	CCR-11 是一种具有抗菌活性的绕丹宁衍生物。 CCR-11 可以抑制 B. subtilis细胞和 HeLa 细胞增殖。 CCR-11 通过抑制 FtsZ 的组装和 GTPase 活性来抑制细菌增殖和细菌胞质分裂。 CCR-11 具有潜在的抗肿瘤活性，可用于研究乳腺癌和小儿骨髓增生异常。
T11929	M2N12	Phosphatase	Metabolism
	M2N12 是一种高度选择性的细胞分裂周期蛋白磷酸酶 25C 抑制剂，IC50值为 0.09 μM。它还抑制 Cdc25A 和 Cdc25B 的活性，IC50值分别为 0.53 μM 和 1.39 μM。它具有抗肿瘤活性，可研究癌症。
T6437	Cefoperazone 头孢哌酮,Cefob,Medocef	Antibacterial; Antibiotic	Microbiology/Virology
	Cefoperazone (Medocef) 是一种半合成的头孢菌素，有抗菌活性。
T10735	CDK4/6/1 Inhibitor Crozbaciclib	CDK	Cell Cycle/Checkpoint
	CDK4/6/1 Inhibitor (Crozbaciclib) 是一种 CDK4/6 抑制剂 (IC50s: 3 and 1 nM). CDK4/6抑制剂是一类用于治疗一些类型的激素受体阳性、her2阴性乳腺癌的化合物，可阻断了乳腺癌细胞分裂和繁殖的过程。
T1600	Doxifluridine Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Doxifluridine (AMC 0101) 是一种胸苷磷酸化酶活化剂，对 PC9-DPE2细胞的 IC50为0.62 μM。它是具有抗肿瘤活性的抗肿瘤剂 5-fluorouracil (5-FU) 的氟嘧啶衍生物和口服前药。
T4433	6-CFDA N-succinimidyl ester Carboxyfluorescein diacetate succinimidyl	Others	Others
	6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) 能够自发且不可逆地与游离胺结合。在流式细胞术实验中用于追踪哺乳动物细胞和细菌的细胞分裂。与多种细胞透化剂结合使用，作为一种有效的、非破坏性的荧光染料，可快速检测细菌细胞。
T2511	Plinabulin 普那布林,NPI-2358	Microtubule Associated	Cytoskeletal Signaling
	Plinabulin (NPI-2358) 是一种抗微管蛋白解聚肿瘤细胞的血管破坏剂，选择性地靶向并结合到微管蛋白的秋水仙碱结合位点，从而中断微管动力学的平衡。它对人肿瘤细胞系具有抑制作用，对 HT-29 细胞系的IC50值为 9.8 nM。
T3661	Citarinostat ACY241,HDAC-IN-2	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Citarinostat (ACY241) 是一种强效、选择性和口服组蛋白脱乙酰酶 (HDAC) 抑制剂，具有抗肿瘤活性，对 HDAC1、HDAC2、HDAC3、HDAC6 和 HDAC8 的 IC50分别为 35、45、46、2.6 和 137 nM。
T1228	Cefonicid sodium Monocid sodium,头孢尼西钠,Cefonicid disodium salt	Antibacterial; Antibiotic	Microbiology/Virology
	Cefonicid sodium (Monocid sodium) 是一种广谱头孢类抗生素, 能抑制细菌细胞壁的形成。
T1213	Piperacillin sodium 哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt	Antibacterial; Antibiotic	Microbiology/Virology
	Piperacillin sodium salt(CL227193) )是一种β-内酰胺类广谱抗生素。
T67509	Cholesteryl Hemisuccinate Cholesterol hydrogen succinate	Apoptosis; DNA/RNA Synthesis; Topoisomerase	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) 是一种经常使用在极性溶液中具有高溶解度的胆固醇类似物，具有保肝、抗癌和抑制肿瘤生长的作用。Cholesteryl Hemisuccinate 抑制对乙酰氨基酚的肝毒性，并防止 AAP 诱导的肝细胞凋亡和坏死。Cholesteryl Hemisuccinate 抑制 DNA 聚合酶和 DNA 拓扑异构酶，从而抑制 DNA 复制和修复以及细胞分裂。
T3615	Evofosfamide 艾伏磷酰胺,TH-302	Apoptosis; Others	Apoptosis; Others
	Evofosfamide (TH-302) 是一种缺氧激活前药，在缺氧 (N2) 和常氧 (21% O2) 环境下，IC50分别为 10 μM 和 1000 μM。
T1408	Capecitabine Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Capecitabine (Capecitibine) 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
T1122	Cephalothin sodium 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin	Antibacterial; Antibiotic	Microbiology/Virology
	Cephalothin sodium (Cefalotin) 是一种头孢类抗生素, 具有广泛的抗菌活性，抑制革兰氏阳性和阴性菌。
T25529	IMM-01	GTPase	GPCR/G Protein
	IMM-01 是一类新型的哺乳动物透明 (mDia) 相关形式的小分子激动剂，其作用于 Rho GTPase 下游以组装肌动蛋白丝，并与微丝组织在迁移和不对称分裂过程中建立和维持细胞极性. GTP 结合的 Rho 通过破坏 DID 和 DAD 自动调节结构域之间的相互作用来激活 mDia 家族成员，从而释放 FH2 结构域以调节肌动蛋白和微管动力学。
T40443	JAK2-IN-6 JAK2-IN-6	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2-IN-6是一种有效的、有选择性的 JAK2抑制剂(ic50为22.86 μg/mL),是一种多取代氨基噻唑衍生物。JAK2-IN-6抑制 JAK2酶的活性，通过干扰与 JAK2相关的信号通路，从而对 JAK2失调的特定疾病产生治疗作用，对 JAK1和JAK3不显示出活性。JAK2是一种参与调节细胞生长和分裂的信号通路的蛋白质。JAK2的异常激活与多种疾病有关，包括某些类型的癌症和炎症性疾病。JAK2-IN-6对癌细胞具有抗增殖活性。
T24126	Gyramide A Gyramide-A	Others	Others
	Gyramide A is an inhibitor of bacterial DNA gyrase. It shows antimicrobial activity and inhibits bacterial cell division.
T19830	Dicapthon AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124	Others	Others
	Dicapthon is an insecticide. Dicapthon increases the occurrence of abnormal cell frequency, decreases the mitotic index, and decreases the nuclear division index.
T34924	Triadimenol Spinnaker,UK199,Baytan,UK 199,UK-199	Others	Others
	Triadimenol is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis, and thus the rate of cell division.
T28305	PC58538 PC-58538,PC 58538	Others	Others
	PC58538 is an inhibitor of FtsZ protein, a important role in the division machinery of bacterial cells.
T23578	(S)-Gyramide A (S)-Gyramide-A,(S)-534F6,(S)534F6,(S) 534F6	Others	Others
	(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.
T38428	Alisertib sodium MLN 8237 sodium	Others	Others
	Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitotic spindle and causes abnormal cell division. At the molecular level, it acts on the AKT/mTOR/AMPK/p38 pathway, leading to the induction of apoptosis and autophagy in leukemic cells. This compound exhibits significant antitumor activity.
T29205	Zarilamide Zarilamid	Others	Others
	Zarilamide is inhibitor of the nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide destructs the microtubule cytoskeleton, resulting in a consequent inhibition of mitosis.
T40782	Metazachlor	Others	Others
	Metazachlor, a member of the chloroacetamide class of herbicides, acts as a long chain fatty acid synthesis inhibitor. It exerts an influence on cell division and tissue differentiation in germinating and emerging weed species.
T70958	Dov-Val-Dil-OH TFA	Others	Others
	Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin.
T31838	Folic acid, methyl- x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid	Others	Others
	Folic acid, methyl- is a nutrient that belongs to the vitamin B family. Folate is significant for the easy conversion of carbohydrates into glucose and is essential in red blood cell formation, cell division, detoxification, and the production of some neu
T32655	l-Ergothionine hydrochloride l-Ergothionine HCl	Others	Others
	l-Ergothionine hydrochloride is a sulfur-containing amino acid, which is only produced by Actinomycetales bacteria and non-yeast-like fungi belonging to the division Basidiomycota and Ascomycota. It was originally isolated from Claviceps purpurea or rye e
T72934	Epothilone E 埃博霉素E	Others	Others
	Epothilone E，作为Epothilone的衍生化合物，通过抑制微管蛋白功能来阻碍细胞分裂，从而展现出抗肿瘤活性。
T40816	Metalaxyl-M Metalaxyl-M,(R)-Metalaxyl	Others	Others
	Metalaxyl-M ((R)-Metalaxyl), the active (R)-enantiomer of Metalaxyl, is a broad-spectrum fungicide that targets protein and ribosomal RNA synthesis in fungi. It is employed in the research of plant diseases attributed to pathogens from the Oomycota division.
T36106	Coumermycin A1	Others	Others
	Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1]. [1]. Tiantian Zhang, et al. SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. Research Article.
T21298	SNS-314 SNS-314 free base,SNS314,SNS 314	Others	Others
	SNS-314, a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity, selectively binds and inhibits AKs A and B, resulting in the inhibition of cell division and proliferation in tumor cells that overexpress AKs.
T78591	Zoxamide RH-7281	Others	Others
	Zoxamide (RH-7281) 是一种抑制辣椒疫霉幼苗中核分裂和破坏微管细胞骨架的卵菌杀菌剂。
T25043	Alestramustine	Others	Others
	Alestramustine is a cytostatic antineoplastic agent. The drug, via its active metabolites, binds to microtubule-associated proteins and β-tubulin and interferes with microtubule function, thereby suppressing cell division. Due to its estrogen moiety, Ales
T11042	Dihydrocytochalasin B	Others	Others
	Dihydrocytochalasin B (H2CB) is a cell division inhibitor that changes the morphology of cells, similar to cytochalasin B. Does not inhibit glucose transport. Dihydrocytochalasin B (H2CB) disrupts the structure of actin and inhibits the ability of growth

化合物

Cat.No: T1907

Synonym: Mitochondrial division inhibitor 1

Target: Apoptosis, Mitophagy, Dynamin, Autophagy

Cat.No: T8513

Target: Others

Cat.No: T12642L

Synonym: TAK-931

Target: CDK

Cat.No: T6393

Target: Kinesin

Cat.No: T21970

Target: GTPase

Cat.No: T21678

Target: PLK

Cat.No: T0849

Synonym: Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶

Target: DHFR, Antifolate, Parasite

Cat.No: T22991

Target: Rho, Ras

Cat.No: T8586

Target: Others

Cat.No: T15141

Synonym: Ravtansine,美登素 DM4

Target: Others, Microtubule Associated, ADC Cytotoxin

(R)-Simurosertib

Cat.No: T12642

Synonym: (R)-TAK-931

Target: CDK

Cat.No: T3256

Synonym: 一甲基澳瑞他汀 F,MonoMethyl auristatin F

Target: Others, Microtubule Associated, ADC Cytotoxin

Monomethyl auristatin E

Cat.No: T6897

Synonym: 一甲基澳瑞他汀E,Vedotin,MMAE

Target: Apoptosis, Microtubule Associated, ADC Cytotoxin

Cat.No: T3352

Target: cholecystokinin, Casein Kinase, Pim, CDK

Cat.No: T1060

Synonym: Flumigal,氟甲喹,R-802

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T14348

Target: Microtubule Associated, ADC Cytotoxin

Cat.No: T25214

Synonym: CCR11,CCR 11

Target: Antibiotic

Cat.No: T11929

Target: Phosphatase

Cat.No: T6437

Synonym: 头孢哌酮,Cefob,Medocef

Target: Antibacterial, Antibiotic

CDK4/6/1 Inhibitor

Cat.No: T10735

Synonym: Crozbaciclib

Target: CDK

Cat.No: T1600

Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

6-CFDA N-succinimidyl ester

Cat.No: T4433

Synonym: Carboxyfluorescein diacetate succinimidyl

Target: Others

Cat.No: T2511

Synonym: 普那布林,NPI-2358

Target: Microtubule Associated

Cat.No: T3661

Synonym: ACY241,HDAC-IN-2

Target: HDAC

Cefonicid sodium

Cat.No: T1228

Synonym: Monocid sodium,头孢尼西钠,Cefonicid disodium salt

Target: Antibacterial, Antibiotic

Piperacillin sodium

Cat.No: T1213

Synonym: 哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt

Target: Antibacterial, Antibiotic

Cholesteryl Hemisuccinate

Cat.No: T67509

Synonym: Cholesterol hydrogen succinate

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase

Cat.No: T3615

Synonym: 艾伏磷酰胺,TH-302

Target: Apoptosis, Others

Cat.No: T1408

Synonym: Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cephalothin sodium

Cat.No: T1122

Synonym: 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin

Target: Antibacterial, Antibiotic

Cat.No: T25529

Target: GTPase

Cat.No: T40443

Synonym: JAK2-IN-6

Target: JAK

Cat.No: T24126

Synonym: Gyramide-A

Target: Others

Cat.No: T19830

Synonym: AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124

Target: Others

Cat.No: T34924

Synonym: Spinnaker,UK199,Baytan,UK 199,UK-199

Target: Others

Cat.No: T28305

Synonym: PC-58538,PC 58538

Target: Others

Cat.No: T23578

Synonym: (S)-Gyramide-A,(S)-534F6,(S)534F6,(S) 534F6

Target: Others

Alisertib sodium

Cat.No: T38428

Synonym: MLN 8237 sodium

Target: Others

Cat.No: T29205

Synonym: Zarilamid

Target: Others

Cat.No: T40782

Target: Others

Dov-Val-Dil-OH TFA

Cat.No: T70958

Target: Others

Folic acid, methyl-

Cat.No: T31838

Synonym: x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid

Target: Others

l-Ergothionine hydrochloride

Cat.No: T32655

Synonym: l-Ergothionine HCl

Target: Others

Cat.No: T72934

Synonym: 埃博霉素E

Target: Others

Cat.No: T40816

Synonym: Metalaxyl-M,(R)-Metalaxyl

Target: Others

Cat.No: T36106

Target: Others

Cat.No: T21298

Synonym: SNS-314 free base,SNS314,SNS 314

Target: Others

Cat.No: T78591

Synonym: RH-7281

Target: Others

Cat.No: T25043

Target: Others

Dihydrocytochalasin B

Cat.No: T11042

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2190	Scoulerine	Apoptosis; Beta-Secretase; BACE; Parasite	Apoptosis; Microbiology/Virology; Neuroscience
	Scoulerine 是抗有丝分裂化合物。它抑制细胞增殖，阻止细胞周期，并诱导癌细胞凋亡。它也是BACE1(淀粉样前体蛋白裂解酶 1) 的抑制剂。
T2223	Kinetin 激动素,6-Furfuryladenine,6-糠氨基嘌呤,N6-Furfuryladenine	Others	Others
	Kinetin (N6-Furfuryladenine) 是 N6-取代腺嘌呤衍生物细胞分裂素家族成员，其中细胞分裂素是一种参与细胞分裂、分化等生理过程的植物生长激素。它具有抗衰老活性。
T13818	Phytohemagglutinin PHA-M,植物血球凝集素,PHA,植物血凝素	Apoptosis	Apoptosis
	Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素，聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂，能够刺激人单核白细胞，可诱导 ChAT mRNA 表达，增强 ACh 合成。
T8211	(±)-Decursinol 紫花前胡醇,3',4'-dihydro-3'-hydroxy-Xanthyletin	Others; Antibacterial	Microbiology/Virology; Others
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) 是来自当归的一种 FtsZ 抑制剂，抑制 B. anthracis 的 FtsZ 聚合，IC50为 102 μM。
T2982	Xanthone Genicide,呫吨酮,氧杂蒽酮,Xanthenone,Benzophenone oxide	Apoptosis; Others; Influenza Virus; Antibacterial; Antifungal	Apoptosis; Microbiology/Virology; Others
	Xanthone (Xanthenone) 是一种从山竹果中分离得到的天然产物，具有抗炎，抗氧化，抗肿瘤，抗过敏，抗细菌，抗真菌和抗病毒活性。在癌变的不同阶段可控制细胞分裂和生长，凋亡，炎症和转移。
T2942	Psoralen Ficusin,Furocoumarin,补骨脂素,psoralene	Apoptosis; Influenza Virus; HIV Protease; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。它具有如抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等多种生物学特性。
T3151	Brassinolide Brassin lactone,24-Epibrassinolide,芸苔素内酯	Apoptosis; Others	Apoptosis; Others
	Brassinolide (Brassin lactone) 是一种植物生长调节剂，可调节植物细胞伸长。
T14304	Aphidicolin	Others	Others
	Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA
T4454	Traumatic Acid Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid	Antioxidant	oxidation-reduction
	Traumatic Acid (Dodec-2-Enedioic Acid) 是一种单不饱和二元羧酸，从菜豆中分离得到。它可减少膜磷脂的过氧化，并表现出抗氧化和对胶原生物合成的刺激作用。它可用于许多与胶原蛋白生物合成障碍和氧化应激有关的皮肤疾病的研究。
TMS2181	trans-Zeatin (E)-Zeatin,玉米素	ERK; MEK; Endogenous Metabolite	MAPK; Metabolism
	trans-Zeatin ((E)-Zeatin) 是植物细胞分裂素，可抑制紫外线诱导的MEK/ERK 的活化，在细胞生长、分化和分裂中起着重要的作用。
TMS2182	trans-Zeatinriboside Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷	Others	Others
	trans-Zeatinriboside (Ribosylzeatin) 是一种细胞分裂素前体，是木质素导管中主要的长距离信号形式，能够调节叶片大小和分生组织活性相关形状。
T7132	(Rac)-Brassinazole BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑	P450	Metabolism
	(Rac)-Brassinazole 是三唑型化合物，是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T1004	6-Benzylaminopurine 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine	Others	Others
	6-Benzylaminopurine (6-BAP) 是一种细胞分裂素，能够通过刺激细胞分裂引起植物生长和发育，抑制呼吸激酶，从而延长绿色蔬菜的保鲜。
TMS2179	Zeatin 玉米素	Others	Others
	Zeatin 是一种来源于腺嘌呤的细胞分裂素。Zeatin 是在玉米属的未成熟玉米粒中发现的。它促进侧芽的生长，当喷洒在分生组织上时会刺激细胞分裂，从而产生更浓密的植物。
T5088	3-Indoleacetic acid sodium Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,吲哚乙酸钠,Heteroauxin sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	3-Indoleacetic acid sodium (Heteroauxin sodium salt) 是一种天然存在的植物生长素类激素。能刺激细胞伸长和分裂，促进植物生长发育。然而，高浓度时，它表现出生长抑制作用，包括生长和阻止茎和根的生长。后一种效应形成了合成生长素被开发为农业除草剂和生物调节剂的基础。
TMM2618	Gibberllin A7 Gibberellin A7,Gibberllin 7,赤霉素GA7	Others	Others
	Gibberllin A7 (Gibberllin 7) 是重要的植物生长激素，可促进植物细胞生长和伸长。它可促进茎和根的快速生长，诱导有丝分裂并启动（打破休眠）并提高种子发芽率。它还参与诸如作为向地力、张力和花卉展示。Gibberellin A3(G1025, G7645) 和 A4 (G7276) 可用作植物生长培养基如 Murashige 和 Skoog 培养基的补充剂。 A3 和 A4 或 Gebberellins 组合的具体作用应在具体的植物应用中确定。
T38141	Glycerophospholipids, cephalins Phosphatidylethanolamines (egg)
	Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物，在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用，可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
T75520	Aplyronine A	Others	Others
	Aplyronine A是具有特异性肌动蛋白解聚活性、抗肿瘤及促凋亡功能的化合物，适用于癌症、肌肉收缩、细胞运动和细胞分裂等研究领域。
TN4890	Rabdosin B	Others	Others
	Rabdosin B shows cytotoxic activity against three human tumour HepG2, GLC-82 and HL-60 cell lines, it induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner. Rabdosin B at higher concentrations inhibits root growth by affecting
TN4249	Ilicol	Others	Others
	Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. They reduce Allium cepa cell

天然产物

Cat.No: TN2190

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Cat.No: T2223

Synonym: 激动素,6-Furfuryladenine,6-糠氨基嘌呤,N6-Furfuryladenine

Target: Others

Phytohemagglutinin

Cat.No: T13818

Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素

Target: Apoptosis

(±)-Decursinol

Cat.No: T8211

Synonym: 紫花前胡醇,3',4'-dihydro-3'-hydroxy-Xanthyletin

Target: Others, Antibacterial

Cat.No: T2982

Synonym: Genicide,呫吨酮,氧杂蒽酮,Xanthenone,Benzophenone oxide

Target: Apoptosis, Others, Influenza Virus, Antibacterial, Antifungal

Cat.No: T2942

Synonym: Ficusin,Furocoumarin,补骨脂素,psoralene

Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis

Cat.No: T3151

Synonym: Brassin lactone,24-Epibrassinolide,芸苔素内酯

Target: Apoptosis, Others

Cat.No: T14304

Target: Others

Cat.No: T4454

Synonym: Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid

Target: Antioxidant

Cat.No: TMS2181

Synonym: (E)-Zeatin,玉米素

Target: ERK, MEK, Endogenous Metabolite

trans-Zeatinriboside

Cat.No: TMS2182

Synonym: Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷

Target: Others

(Rac)-Brassinazole

Cat.No: T7132

Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

Target: P450

6-Benzylaminopurine

Cat.No: T1004

Synonym: 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine

Target: Others

Cat.No: TMS2179

Synonym: 玉米素

Target: Others

3-Indoleacetic acid sodium

Cat.No: T5088

Synonym: Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,吲哚乙酸钠,Heteroauxin sodium salt

Target: Others, Endogenous Metabolite

Cat.No: TMM2618

Synonym: Gibberellin A7,Gibberllin 7,赤霉素GA7

Target: Others

Glycerophospholipids, cephalins

Cat.No: T38141

Synonym: Phosphatidylethanolamines (egg)

Cat.No: T75520

Target: Others

Cat.No: TN4890

Target: Others

Cat.No: TN4249

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03002	FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) ftsQ,Cell division protein FtsQ	Mycobacterium tuberculosis	E. coli
	Essential cell division protein. FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P9WNA0.
TMPY-01715	CDC37 Protein, Human, Recombinant (GST) cell division cycle 37,P50CDC37	Human	Baculovirus Insect Cells
	CDC37 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 70.7 kDa and the accession number is A0A024R7B7.
TMPH-00666	FtsZ Protein, E. coli O157:H7, Recombinant (His & Myc) Cell division protein FtsZ,ftsZ	E. coli	E. coli
	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
TMPH-03527	FtsZ Protein, S. aureus, Recombinant (His) ftsZ,Cell division protein FtsZ	Staphylococcus aureus	E. coli
	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. FtsZ Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The ...
TMPY-03558	CDC37 Protein, Mouse, Recombinant p50Cdc37,cell division cycle 37,p50	Mouse	Baculovirus Insect Cells
	CDC37 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 44.7 kDa and the accession number is Q61081.
TMPY-03534	CDC37 Protein, Mouse, Recombinant (His & GST) cell division cycle 37,p50,p50Cdc37	Mouse	Baculovirus Insect Cells
	CDC37 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.4 kDa and the accession number is Q61081.
TMPY-02308	CDC42 Protein, Human, Recombinant (GST) cell division cycle 42,G25K,CDC42Hs	Human	E. coli
	CDC42 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 48.1 kDa and the accession number is P60953-2.
TMPH-03150	FtsZ Protein, Porphyromonas gingivalis, Recombinant (His) Cell division protein FtsZ,ftsZ	Porphyromonas gingivalis	E. coli
	FtsZ Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 56.3 kDa and the accession number is B2RIF5.
TMPH-00684	FtsZ Protein, E. coli O6:H1, Recombinant (His & SUMO) Cell division protein FtsZ,ftsZ	E. coli	E. coli
	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. FtsZ Protein, E. coli O6:H1, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHi...
TMPH-01074	CDC20 Protein, Human, Recombinant (His & Myc) Cell division cycle protein 20 homolog,CDC20,p55CDC	Human	E. coli
	CDC20 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.2 kDa and the accession number is Q12834.
TMPH-01167	CDK1 Protein, Human, Recombinant (His) p34 protein kinase,Cell division control protein 2 ...	Human	E. coli
	CDK1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01169	CDK4 Protein, Human, Recombinant (His) Cyclin-dependent kinase 4,CDK4,Cell division protei...	Human	E. coli
	CDK4 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01171	CDK5 Protein, Human, Recombinant Serine/threonine-protein kinase PSSALRE,Cyclin-dependent-lik...	Human	E. coli
	CDK5 Protein, Human, Recombinant is expressed in E. coli.
TMPH-01172	CDK7 Protein, Human, Recombinant (His) 39 kDa protein kinase,Cyclin-dependent kinase 7,CDK-activati...	Human	Baculovirus Insect Cells
	CDK7 Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPH-01173	CDK7 Protein, Human, Recombinant Cyclin-dependent kinase 7,Cell division protein kin...	Human	E. coli
	CDK7 Protein, Human, Recombinant is expressed in E. coli.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPH-00657	NlpD Protein, E. coli, Recombinant (His & SUMO) Murein hydrolase activator NlpD,nlpD	E. coli	E. coli
	Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division.
TMPH-02400	Pal Protein, Legionella pneumophila, Recombinant (His) 19 kDa surface antigen,Peptidoglycan-associated lipoprotein,...	Legionella pneumophila	P. pastoris (Yeast)
	Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan.
TMPH-02399	Pal Protein, Legionella pneumophila, Recombinant (E. coli, His) pal,19 kDa surface antigen,Peptidoglycan-associated lipoprot...	Legionella pneumophila	E. coli
	Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan.
TMPH-03086	Pal Protein, Pasteurella multocida, Recombinant (His & SUMO) Peptidoglycan-associated lipoprotein,pal,Outer membrane prot...	Pasteurella multocida	E. coli
	Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Pal Protein, Pasteurella multocida, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is Q51886.
TMPK-01480	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated IAP4,Survivin,API4,BIRC5,MHC,MHC I,EPR-1,survivin variant 3 ...	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
TMPH-00703	Pal Protein, E. coli, Recombinant (His & Myc) Peptidoglycan-associated lipoprotein,pal,Tol-Pal system lipo...	E. coli	E. coli
	Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. The Tol-Pal system is also required for polar localization of chemoreceptors clusters. The system also appears to be required for the activity of several outer membrane-localized enzymes with cell wall remodeling activity.
TMPK-01516	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi) IAP4,survivin variant 3 alpha,BIRC5,Survivin,EPR-1,API4,MHC ...	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
TMPH-03021	PstP Protein, Mycobacterium tuberculosis, Recombinant (His) Mycobacterial Ser/Thr phosphatase,PP2C-family Ser/Thr phosph...	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection.
TMPK-00392	FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1	Human	HEK293 Cells
	Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb...
TMPH-02693	GNAI2 Protein, Mouse, Recombinant (His) Guanine nucleotide-binding protein G(i) subunit alpha-2,Gnai...	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.
TMPH-03022	PstP Protein, Mycobacterium tuberculosis, Recombinant PP2C-family Ser/Thr phosphatase,pstP,Serine/threonine protei...	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection. PstP Protein, Mycobacterium tuberculosis, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.3 kDa and the accession number is P9WHW4.
TMPK-00394	FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1	Human	HEK293 Cells
	Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ...
TMPK-01517	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi) survivin variant 3 alpha,MHC I,BIRC5,EPR-1,IAP4,Survivin,API...	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
TMPH-00368	FGF-2 Protein, Chicken, Recombinant (His) Heparin-binding growth factor 2,FGF2,Fibroblast growth facto...	Chicken	P. pastoris (Yeast)
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P48800.
TMPH-00169	PBP 3 Protein, Bacillus subtilis, Recombinant (His) Penicillin-binding protein 3,PSPB20,Penicillin-binding prote...	Bacillus subtilis	E. coli
	Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Probably required for both cortical and vegetative peptidoglycan synthesis. Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential. Confers resistance to oxacillin and cephalexin. PBP 3 Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.2 kDa and the accession number is P429...
TMPH-03438	CHS1 Protein, S. cerevisiae, Recombinant (His) CHS1,Chitin-UDP acetyl-glucosaminyl transferase 1,Chitin syn...	Saccharomyces cerevisiae	E. coli
	Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation during adverse conditions. CHS1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is P08004.
TMPH-00369	FGF-2 Protein, Chicken, Recombinant (His & Myc) Basic fibroblast growth factor,Fibroblast growth factor 2,He...	Chicken	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.8 kDa and the accession number is P48800.
TMPH-00081	CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His) CDKB1-2,CDKB1;2,Cyclin-dependent kinase B1-2	Arabidopsis thaliana	P. pastoris (Yeast)
	Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage. CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.6 kDa and the accessio...
TMPH-01752	Nestin/NES Protein, Human, Recombinant (His) Nestin,NES	Human	P. pastoris (Yeast)
	Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. Nestin/NES Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 2...
TMPH-03203	FGFb Protein, Rabbit, Recombinant (His & SUMO) Basic fibroblast growth factor,Fibroblast growth factor 2,FG...	Rabbit	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp...
TMPK-00329	TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated LDS2B,TbetaR-II,TGFβR2,LDS2,RIIC,TGF-β RII/TGFBR2,TβR-II,TGF...	Human	HEK293 Cells
	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi...
TMPK-00328	TGFBR2 Protein, Human, Recombinant (mFc & Avi) TAAD2,LDS2B,LDS2,MFS2,TGFBR2,AAT3,LDS1B,TGFβR2,TbetaR-II,TGF...	Human	HEK293 Cells
	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The pred...
TMPJ-00907	GADD45A Protein, Human, Recombinant (His) GADD45,DDIT1,Growth Arrest and DNA Damage-Inducible Protein ...	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating ...
TMPJ-00944	PPP1CC Protein, Human, Recombinant (His) PP-1G,Serine/Threonine-Protein Phosphatase PP1-Gamma Catalyt...	Human	E. coli
	Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1C...
TMPJ-01407	FIS1 Protein, Human, Recombinant (His) FIS1 Homolog,FIS1,Tetratricopeptide Repeat Protein 11,TPR Re...	Human	E. coli
	Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus i...
TMPY-05095	RAF1 Protein, Human, Recombinant (His & GST) Raf-1 proto-oncogene, serine/threonine kinase,CRAF,NS5,CMD1N...	Human	Baculovirus Insect Cells
	RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell p...
TMPJ-00769	TK1 Protein, Human, Recombinant (His) cytosolic,Thymidine kinase,TK1	Human	HEK293 Cells
	Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme...
TMPH-01240	MCM2 Protein, Human, Recombinant (His) DNA replication licensing factor MCM2,Nuclear protein BM28,M...	Human	E. coli
	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active ...
TMPY-04458	TRIB2 Protein, Human, Recombinant (His & GST) TRIBBLE,tribbles pseudokinase 2,TRIB2,C5FW,FLJ57420,GS3955,T...	Human	Baculovirus Insect Cells
	Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems and physiological processes, including development, together with their potential involvement in diabetes and cancer, has generated considerable interest in these proteins. Tribbles have been reported to regulate the activation of some intracellular signalling pathways with roles e...
TMPY-01412	Glypican 5 Protein, Human, Recombinant (His) glypican 5	Human	Baculovirus Insect Cells
	Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control of cell division and growth regulation. So far, six members (Glypican-1/GPC1, Glypican-2/GPC2, Glypican-3/GPC3, Glypican-4/GPC4, Glypican-5/GPC5, Glypican-6/GPC6) of this family are known in the vertebrates. In the adult, Glypican-5 is primarily expressed in the brain. It is als...
TMPJ-01316	IL-21 Protein, Mouse, Recombinant (His) 白细胞介素,IL-21,Interleukin-21,白介素,IL21	Mouse	E. coli
	Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, respectively. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex (IL-21 specific IL-21 R). IL-21 is a cytokine that has potent regulatory effects on cells of the immun...
TMPY-04558	NEK7 Protein, Human, Recombinant (His & GST) NIMA-related kinase 7	Human	Baculovirus Insect Cells
	NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily. NEKs (NIMA-related kinases) are mammalian serine/threonine (Ser/Thr) protein kinases structurally related to Aspergillus NIMA (Never in Mitosis, gene A), which plays essential roles in mitotic signaling. NEKs share an amino-terminal catalytic domain related to NIMA, an Aspergillus kinase involved in the control of several aspects of mitosis, and dive...
TMPY-01332	HIST1H3A Protein, Human, Mouse, Recombinant Histone H3.1,histone cluster 1, H3a,Histone H3	Human,Mouse	E. coli
	Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expressed during the S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby pla...
TMPY-04566	CAMKV Protein, Human, Recombinant (His & GST) 1G5,VACAMKL,CaM kinase-like vesicle-associated	Human	Baculovirus Insect Cells
	CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase family. CAMKV contains oneprotein kinase domain. It is predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. CAMKV may be associated with vesicular structures. It does not appear to have detectable kinase activity. ...
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重组蛋白

FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Cat.No: TMPH-03002

Species: Mycobacterium tuberculosis

Expression System: E. coli

CDC37 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01715

Species: Human

Expression System: Baculovirus Insect Cells

FtsZ Protein, E. coli O157:H7, Recombinant (His & Myc)

Cat.No: TMPH-00666

Species: E. coli

Expression System: E. coli

FtsZ Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03527

Species: Staphylococcus aureus

Expression System: E. coli

CDC37 Protein, Mouse, Recombinant

Cat.No: TMPY-03558

Species: Mouse

Expression System: Baculovirus Insect Cells

CDC37 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-03534

Species: Mouse

Expression System: Baculovirus Insect Cells

CDC42 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02308

Species: Human

Expression System: E. coli

FtsZ Protein, Porphyromonas gingivalis, Recombinant (His)

Cat.No: TMPH-03150

Species: Porphyromonas gingivalis

Expression System: E. coli

FtsZ Protein, E. coli O6:H1, Recombinant (His & SUMO)

Cat.No: TMPH-00684

Species: E. coli

Expression System: E. coli

CDC20 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01074

Species: Human

Expression System: E. coli

CDK1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01167

Species: Human

Expression System: E. coli

CDK4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01169

Species: Human

Expression System: E. coli

CDK5 Protein, Human, Recombinant

Cat.No: TMPH-01171

Species: Human

Expression System: E. coli

CDK7 Protein, Human, Recombinant (His)

Cat.No: TMPH-01172

Species: Human

Expression System: Baculovirus Insect Cells

CDK7 Protein, Human, Recombinant

Cat.No: TMPH-01173

Species: Human

Expression System: E. coli

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

NlpD Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00657

Species: E. coli

Expression System: E. coli

Pal Protein, Legionella pneumophila, Recombinant (His)

Cat.No: TMPH-02400

Species: Legionella pneumophila

Expression System: P. pastoris (Yeast)

Pal Protein, Legionella pneumophila, Recombinant (E. coli, His)

Cat.No: TMPH-02399

Species: Legionella pneumophila

Expression System: E. coli

Pal Protein, Pasteurella multocida, Recombinant (His & SUMO)

Cat.No: TMPH-03086

Species: Pasteurella multocida

Expression System: E. coli

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01480

Species: Human

Expression System: HEK293 Cells

Pal Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00703

Species: E. coli

Expression System: E. coli

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01516

Species: Human

Expression System: HEK293 Cells

PstP Protein, Mycobacterium tuberculosis, Recombinant (His)

Cat.No: TMPH-03021

Species: Mycobacterium tuberculosis

Expression System: E. coli

FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00392

Species: Human

Expression System: HEK293 Cells

GNAI2 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02693

Species: Mouse

Expression System: E. coli

PstP Protein, Mycobacterium tuberculosis, Recombinant

Cat.No: TMPH-03022

Species: Mycobacterium tuberculosis

Expression System: E. coli

FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00394

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01517

Species: Human

Expression System: HEK293 Cells

FGF-2 Protein, Chicken, Recombinant (His)

Cat.No: TMPH-00368

Species: Chicken

Expression System: P. pastoris (Yeast)

PBP 3 Protein, Bacillus subtilis, Recombinant (His)

Cat.No: TMPH-00169

Species: Bacillus subtilis

Expression System: E. coli

CHS1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03438

Species: Saccharomyces cerevisiae

Expression System: E. coli

FGF-2 Protein, Chicken, Recombinant (His & Myc)

Cat.No: TMPH-00369

Species: Chicken

Expression System: E. coli

CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00081

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

Nestin/NES Protein, Human, Recombinant (His)

Cat.No: TMPH-01752

Species: Human

Expression System: P. pastoris (Yeast)

FGFb Protein, Rabbit, Recombinant (His & SUMO)

Cat.No: TMPH-03203

Species: Rabbit

Expression System: E. coli

TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated

Cat.No: TMPK-00329

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (mFc & Avi)

Cat.No: TMPK-00328

Species: Human

Expression System: HEK293 Cells

GADD45A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00907

Species: Human

Expression System: E. coli

PPP1CC Protein, Human, Recombinant (His)

Cat.No: TMPJ-00944

Species: Human

Expression System: E. coli

FIS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01407

Species: Human

Expression System: E. coli

RAF1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-05095

Species: Human

Expression System: Baculovirus Insect Cells

TK1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00769

Species: Human

Expression System: HEK293 Cells

MCM2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01240

Species: Human

Expression System: E. coli

TRIB2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04458

Species: Human

Expression System: Baculovirus Insect Cells

Glypican 5 Protein, Human, Recombinant (His)

Cat.No: TMPY-01412

Species: Human

Expression System: Baculovirus Insect Cells

IL-21 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01316

Species: Mouse

Expression System: E. coli

NEK7 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04558

Species: Human

Expression System: Baculovirus Insect Cells

HIST1H3A Protein, Human, Mouse, Recombinant

Cat.No: TMPY-01332

Species: Human,Mouse

Expression System: E. coli

CAMKV Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04566

Species: Human

Expression System: Baculovirus Insect Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T70808	Cabazitaxel-d6
	Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...
TMIJ-0157	Cefoperazone-d5
	Cefoperazone-d5 是 Cefoperazone 的氘代化合物。Cefoperazone 的 CAS 号为 62893-19-0。Cefoperazone是一种半合成的头孢菌素，有抗菌活性。
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。

同位素标记化合物

Cat.No: T70808

Cefoperazone-d5

Cat.No: TMIJ-0157

Capecitabine-d11

Cat.No: TMID-0242

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