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TMPY-02700
|
BCL2 Protein, Human, Recombinant (His)
Bcl-2,PPP1R50,B-cell CLL/lymphoma 2
|
Human
|
E. coli
|
|
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins... |
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TMPY-02603
|
STAT6 Protein, Human, Recombinant (His)
STAT6C,IL-4-STAT,STAT6B,signal transducer and activator of t...
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Human
|
Baculovirus Insect Cells
|
|
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators... |
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TMPJ-00038
|
IL-7 Protein, Mouse, Recombinant (His)
interleukin-7,白介素,IL-7,IL-7 interleukin-7,PBGF,Lymphopoietin...
|
Mouse
|
HEK293 Cells
|
|
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell... |
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TMPY-03962
|
AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF
|
Human
|
HEK293 Cells
|
|
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... |
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TMPY-00150
|
IGF2/IGF-II Protein, Human, Recombinant
PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-like growth factor 2
|
Human
|
P. pastoris (Yeast)
|
|
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br... |
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TMPK-00077
|
EPO/Erythropoietin Protein, Human, Recombinant
EPO,MVCD2,红细胞生长素,Epoetin,Erythropoietin,EP
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Human
|
HEK293 Cells
|
|
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition improvement, neurogenesis, and anti-fibrotic, anti-apoptotic, anti-oxidative, and anti-inflammatory effects. |
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TMPY-01561
|
PIG3 Protein, Human, Recombinant (His)
TP53I3,PIG3,tumor protein p53 inducible protein 3
|
Human
|
E. coli
|
|
Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of... |
|
TMPH-01667
|
MT1X Protein, Human, Recombinant (GST)
Metallothionein-IX,Metallothionein-1X,MT1X
|
Human
|
E. coli
|
|
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling. MT1X Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 32.9 kDa and the accession number is P80297. |
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TMPY-03974
|
Bim Protein, Human, Recombinant (His)
BAM,BCL2-like 11 (apoptosis facilitator),BIM,BOD
|
Human
|
E. coli
|
|
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L11 contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. BCL2L11 gene functions as an essential initiator of apoptosis in thymoc... |
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TMPY-03434
|
BMF Protein, Human, Recombinant (His)
Bcl2 modifying factor
|
Human
|
E. coli
|
|
BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular d... |
|
TMPJ-00584
|
Bc1-w Protein, Human, Recombinant (His)
Apoptosis Regulator Bcl-W,KIAA0271,Bcl-2-Like Protein 2,Bcl2...
|
Human
|
E. coli
|
|
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone... |
|
TMPY-04936
|
BCL2A1 Protein, Human, Recombinant (His)
BFL1,ACC1,ACC-2,GRS,ACC-1,HBPA1,BCL2 related protein A1,BCL2...
|
Human
|
E. coli
|
|
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der... |
|
TMPK-00799
|
ANXA1 Protein, Mouse, Recombinant (His)
Calpactin-2,LPC1,Annexin-1,Annexin I,ANXA1,p35,Chromobindin-...
|
Mouse
|
E. coli
|
|
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Mouse, Re... |
|
TMPK-01291
|
ANXA1 Protein, Cynomolgus, Recombinant (His)
Lipocortin I,Calpactin-2,ANX1,ANXA1,Annexin A1,Annexin I,LPC...
|
Cynomolgus
|
E. coli
|
|
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Cynomolgu... |
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TMPK-00768
|
ANXA1 Protein, Human, Recombinant (His)
Annexin A1,Calpactin II,ANX1,p35,Lipocortin I,ANXA1,Calpacti...
|
Human
|
E. coli
|
|
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Human, Re... |
|
TMPJ-01066
|
CYCS Protein, Human, Recombinant (His)
CYC,Cytochrome C,CYCS
|
Human
|
E. coli
|
|
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic... |
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TMPK-00555
|
CDH17 Protein, Cynomolgus, Recombinant (His)
Cdh17,HPT-1,FLJ26931,LI-cadherin,BILL-cadherin,P130,Cadherin...
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Cynomolgus
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Cynomolgus, Recombinant (His) is expressed i... |
|
TMPK-00948
|
CDH17 Protein, Human, Recombinant (hFc)
Cdh17,cadherin-16,FLJ26931,Cadherin-17,HPT-1,P130,CDH16,LI-c...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK... |
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TMPK-00950
|
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
HPT-1,P130,MGC138218,LI-cadherin,FLJ26931,cadherin-16,Cdh17,...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) is expre... |
|
TMPK-01223
|
CDH17 Protein, Mouse, Recombinant (His)
CDH16,LI-cadherin,Cdh17,MGC138218,HPT-1,MGC142024,FLJ26931,B...
|
Mouse
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Mouse, Recombinant (His) is expressed in HEK... |
|
TMPK-00473
|
CDH17 Protein, Rhesus macaque, Recombinant (His)
CDH16,Cdh17,MGC142024,Cadherin-17,cadherin-16,P130,MGC138218...
|
Rhesus
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is express... |
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TMPK-01224
|
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
P130,BILL-cadherin,LI-cadherin,MGC138218,FLJ26931,CDH16,Cadh...
|
Mouse
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant ... |
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TMPK-00949
|
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
CDH16,P130,MGC142024,Cdh17,FLJ26931,Cadherin-17,MGC138218,ca...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is express... |
|
TMPK-00952
|
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
BILL-cadherin,Cadherin-17,LI-cadherin,CDH16,cadherin-16,Cdh1...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) is exp... |
|
TMPK-00947
|
CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
CDH16,Cdh17,P130,cadherin-16,HPT-1,LI-cadherin,Cadherin-17,B...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated... |
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TMPK-00953
|
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
Cdh17,CDH16,MGC138218,BILL-cadherin,HPT-1,cadherin-16,MGC142...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) is expre... |
|
TMPK-00951
|
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
FLJ26931,CDH16,LI-cadherin,MGC138218,cadherin-16,Cadherin-17...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, R... |
|
TMPY-03416
|
TNFAIP8 Protein, Human, Recombinant (His)
GG2-1,tumor necrosis factor, alpha-induced protein 8,SCCS2,S...
|
Human
|
E. coli
|
|
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to prom... |
|
TMPY-00151
|
Alpha SNAP Protein, Human, Recombinant (His)
N-ethylmaleimide-sensitive factor attachment protein, alpha,...
|
Human
|
E. coli
|
|
NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of s... |
|
TMPH-01213
|
DNASE1L3 Protein, Human, Recombinant (His)
DNase I homolog protein DHP2,DNAS1L3,DNase I-like 3,Deoxyrib...
|
Human
|
Baculovirus Insect Cells
|
|
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... |
|
TMPH-01214
|
DNASE1L3 Protein, Human, Recombinant
DHP2,Deoxyribonuclease I-like 3,Deoxyribonuclease gamma,DNas...
|
Human
|
E. coli
|
|
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... |
|
TMPH-01212
|
DNASE1L3 Protein, Human, Recombinant (His & Myc)
LSD,Liver and spleen DNase,Deoxyribonuclease I-like 3,DNAS1L...
|
Human
|
E. coli
|
|
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... |
|
TMPY-02084
|
Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)
MT-TRX,RP5-1119A7. 13-005,TRX2,MTRX,thioredoxin 2
|
Human
|
E. coli
|
|
Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small ... |
|
TMPY-01187
|
Rac1 Protein, Human, Recombinant (GST)
Rac-1,p21-Rac1,MIG5,ras-related C3 botulinum toxin substrate...
|
Human
|
Baculovirus Insect Cells
|
|
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for RAC1 gene. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, bind... |
|
TMPY-02001
|
RTN4 Protein, Human, Recombinant (GST)
UNG1,NOGO,reticulon 4,RTN4-A,Nbla00271,NOGO-A,RTN-X,NSP,UNG1...
|
Human
|
E. coli
|
|
Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that contains one reticulon domain. Isoform 1 of RTN4 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 of RTN4 is widely expressed except for the liver. Isoform 3 of RTN4 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 ... |
|
TMPY-04455
|
PKC iota Protein, Human, Recombinant (GST)
PKCI,nPKC-iota,protein kinase C, ι,DXS1179E,nPKC-ι,protein k...
|
Human
|
Baculovirus Insect Cells
|
|
Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and PKC subfamily. PRKCI contains one AGC-kinase C-terminal domain, one OPR domain, one phorbol-ester/DAG-type zinc finger and one protein kinase domain. PRKCI is predominantly expressed in lung and brain, but also expressed at lower levels in many tissues includ... |
|
TMPH-02613
|
ATF-5 Protein, Mouse, Recombinant (His & Myc)
Transcription factor ATFx,Transcription factor-like protein ...
|
Mouse
|
E. coli
|
|
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip... |
|
TMPH-01503
|
Humanin Protein, Human, Recombinant (hFc)
MT-RNR2,Humanin,Humanin mitochondrial
|
Human
|
HEK293 Cells
|
|
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... |
|
TMPH-01502
|
Humanin Protein, Human, Recombinant (GST)
Humanin,Humanin mitochondrial,MT-RNR2
|
Human
|
E. coli
|
|
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... |
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