tCFA15

Name: tCFA15
Brand: TargetMol
SKU: T13917
Price: 196 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T13917Cas号 220757-88-0

tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.

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tCFA15

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产品编号 T13917Cas号 220757-88-0

tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.

规格	价格	库存
2 mg	¥ 2,480	5日内发货
5 mg	¥ 2,890	5日内发货
25 mg	¥ 10,500	6-8周
50 mg	¥ 13,700	6-8周
100 mg	¥ 19,500	6-8周
1 mL x 10 mM (in DMSO)	¥ 3,180	5日内发货

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产品介绍

生物活性

产品描述

tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.

体外活性

tCFA15 (10 nM-1μM) dose-dependently promotes the differentiation of neural stem cell-derived neurospheres by promoting neurons at the expense of astrocytes, and this effect is through Notch1. tCFA15 (1 μM) specifically decreases the level of Notch1 mRNA in spheres, and such an effect is also observed in decreases Notch1 expression in neuronal and glial cell cultures[1]. tCFA15 stimulates arginine vasopressin secretion in nerve terminals of the neurohypophysis[2].

化学信息

分子量	364.61
分子式	C₂₄H₄₄O₂
CAS No.	220757-88-0
密度	0.910 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 130 mg/mL (356.56 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7427 mL	13.7133 mL	27.4266 mL	137.1328 mL
5 mM	0.5485 mL	2.7427 mL	5.4853 mL	27.4266 mL
10 mM	0.2743 mL	1.3713 mL	2.7427 mL	13.7133 mL
20 mM	0.1371 mL	0.6857 mL	1.3713 mL	6.8566 mL
50 mM	0.0549 mL	0.2743 mL	0.5485 mL	2.7427 mL
100 mM	0.0274 mL	0.1371 mL	0.2743 mL	1.3713 mL