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Search Results for " urinary "

Targets Recommended: Others

160

抑制剂 & 化合物

43

天然产物

17

重组蛋白

14

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T19417	Urinary Incontinence-Targeting Compound 1	Others	Others
	Urinary Incontinence-Targeting Compound 1, used in the research of urinary incontinence, is a sulfonanilide derivative.
T76240	Urinary Trypsin Inhibitor Fragment
	Urinary Trypsin Inhibitor Fragment，一种通过蛋白水解生成的尿胰蛋白酶抑制剂片段，能通过有限蛋白水解抑制肿瘤细胞侵袭。
T1049L	Oxybutynin Oxytrol,奥昔布宁,Ditropan,Oxibutyninum	Potassium Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	Oxybutynin (Ditropan) 是一种抗胆碱能药，抑制血管 Kv 通道，IC50为 11.51 μM，可用于治疗尿失禁和膀胱过度活动症。
T1049	Oxybutynin chloride Oxybutynin hydrochloride,盐酸奥昔布宁,Oxybutynin HCl	Potassium Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	Oxybutynin chloride (Oxybutynin HCl) 是一种抗胆碱能药物，用于缓解泌尿和膀胱困难。它抑制血管 Kv 通道，IC50为 11.51 μM。
T8365	Methenamine Hippurate	Antibacterial	Microbiology/Virology
	Methenamine hippurate 是一种口服活性尿液广谱抗菌剂。它对大多数常见的尿路病原体有效。
T8133	SulfadiMethoxine sodium	Anti-infection; Antibacterial; Antibiotic	Microbiology/Virology
	SulfadiMethoxine sodium 是一种磺胺类抗生素，可研究由多种感染引起的疾病。
T1444	Lomefloxacin 洛美沙星,SC47111A	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Lomefloxacin (SC47111A) 是一种广谱喹诺酮类抗生素，具有抗菌活性。它可研究支气管炎、尿路感染、结膜炎、外耳炎和中耳炎。
T1078	Sulfadimethoxine Sulphadimethoxine,磺胺二甲氧嗪	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfadimethoxine (Sulphadimethoxine) 是一种磺胺类抗生素，用于多种感染引起的疾病的研究。
T3126	Bethanechol chloride (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride	AChR	Neuroscience
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) 是一种拟副交感神经剂，是毒蕈碱型受体 (mAChR) 激动剂，通过直接刺激副交感神经系统的 mAChR 发挥作用。
T16789	Rosoxacin 罗索沙星,Acrosoxacin	Antibacterial; Antibiotic	Microbiology/Virology
	Rosoxacin (Acrosoxacin) 是具有口服活性的喹诺酮类抗生素，具有广谱的抗菌活性，抑制革兰氏阴性菌，包括淋病奈瑟氏球菌(MIC90=0.03 mg/ml)。它在尿路感染中有应用的潜能。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
T5513	RO-3	P2X Receptor	Membrane transporter/Ion channel; Neuroscience
	RO3 是一种能透过大脑的P2X3和P2X2/3拮抗剂，口服有活性。它对人同型多聚体 P2X3和异型多聚体 P2X2/3受体的 pIC50分别为 5.9 和 7.0。
T5521	Bropirimine U-54461,溴匹立明	TLR	Immunology/Inflammation
	Bropirimine (U-54461) 是 toll 样受体 7(TLR7)的合成激动剂，可通过 TLR7 介导 IFN-β 的产生抑制破骨细胞前体细胞向破骨细胞分化。它是一种生物反应调节剂，通过诱导淋巴因子起作用，在膀胱和上尿路的原位移行细胞癌中具有抗癌活性。
T0748	Sulfameter 5-Methoxysulfadiazine,Sulfametoxydiazine,磺胺对甲氧嘧啶	DHFR; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Sulfameter (Sulfametoxydiazine) 是一种长效磺胺类抗生素，具有抗菌活性。它可研究尿路感染和麻风病。
T5023	Propiverine hydrochloride	Others; Calcium Channel; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
	Propiverine hydrochloride 是一种痉挛剂，具有钙拮抗和抗胆碱能特性，用于研究膀胱过度活动和尿失禁。
T10952	Dabuzalgron 达布扎琼,Ro 115-1240	Apoptosis; Adrenergic Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	Dabuzalgron (Ro 115-1240) 是一种口服活性选择性 α-1A 肾上腺素受体激动剂，用于治疗尿失禁。它通过维持线粒体功能来预防多柔比星引起的心脏毒性。
T0274	Cinoxacin 西诺沙星,Compound 64716	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Cinoxacin (Compound 64716) 是一种喹诺酮类的合成抗生素, 与Oxolinic acid 和 Nalidixic acid 活性相似。
T0396	Pipemidic acid 吡哌酸,Acido pipemidico	Antibacterial; Antibiotic	Microbiology/Virology
	Pipemidic acid (Acido pipemidico) 是一种新型抗菌剂，对革兰氏阴性菌和某些革兰氏阳性细菌具有活性，可研究肠道、泌尿和胆道感染。
T1070	Cefmetazole sodium 头孢美唑钠,Sodium cefmetazole	Antibacterial; Antibiotic	Microbiology/Virology
	Cefmetazole sodium (Sodium cefmetazole) 是具有广谱抗菌活性的半合成头孢霉素抗生素。它通过与青霉素结合蛋白结合，阻止肽聚糖的交联，导致细胞壁完整性的丧失。它可研究妇科、腹腔内、尿道、呼吸道和皮肤和软组织感染。
T1472	Trospium chloride Spasmex,Sanctura,曲司氯铵,曲司氯胺	AChR	Neuroscience
	Trospium chloride (Spasmex) 是一种可口服的特异竞争性毒蕈碱胆碱能受体拮抗剂，可与毒蕈碱受体 M1、M2 和 M3 高亲和力结合，具有抗毒蕈碱活性。
T0601	Monobenzyl phthalate 邻苯二甲酸单苄酯,Phthalic Acid Monobenzyl Ester	Others; Endogenous Metabolite	Metabolism; Others
	Phthalic Acid Monobenzyl Ester 是一种暴露于邻苯二甲酸盐(如，邻苯二甲酸二乙基己酯)后的尿代谢物 (urinary metabolite)，具有雌激素作用。。
T1625	Lomefloxacin hydrochloride Lomefloxacin HCl,盐酸洛美沙星,Okacyn,Maxaquin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Lomefloxacin hydrochloride (Okacyn) 是一种广谱喹诺酮类抗生素，具有抗菌活性。它可研究支气管炎、尿路感染、结膜炎、外耳炎和中耳炎。
T6349	Sitafloxacin Hydrate 西他沙星水合物,DU-6859a,DU6859a hydrate	Antibacterial; Antibiotic	Microbiology/Virology
	Sitafloxacin Hydrate (DU-6859a) 是一种口服有效的氟喹诺酮类抗生素，在体外可对抗广泛的革兰氏阳性和阴性细菌有活性。Sitafloxacin 可研究呼吸道感染和尿路感染。
T8139	Sulfamethoxazole sodium 新诺明钠,Ro 4-2130 sodium,磺胺甲恶唑钠	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Sulfamethoxazole sodium (Ro 4-2130 sodium) 是一种磺胺类抗菌素。它常用于各种尿道病原体的研究，与 Trimethoprim 联用，可用于尿路感染的研究。
T0099	Tolterodine tartrate Detrol LA,PNU-200583E,Kabi-2234,酒石酸托特罗定	AChR	Neuroscience
	Tolterodine tartrate (PNU-200583E) 是毒蕈碱受体的有效拮抗剂。它在体内显示出对膀胱和唾液腺的选择性。
T1233	Oxolinic acid Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox	Dopamine Receptor; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology; Neuroscience
	Oxolinic acid (Nidantin) 是一种抗生素，对革兰氏阴性菌和革兰氏阳性菌均有效，可研究急性和慢性尿路感染。它是一种 DNA/RNA 合成抑制剂，也是一种多巴胺摄取抑制剂，能刺激小鼠的活跃过度。
T1504	Silodosin 西洛多辛,KAD 3213,KMD 3213	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Silodosin (KAD 3213) 是有选择性的、强效的、口服活性的 α1A-adrenergic receptor 阻滞剂，是一种有效且耐受性良好的试剂，可用于研究 LUTS/BPH。它对 α1A-AR 表现出高度的亲和力，是 α1B-AR 和 α1D-AR 亲和力的 162 和 50 倍。
T5189	Omadacycline PTK 0796,Amadacycline	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂，是四环素类抗生素。它与 30S 核糖体亚基结合，抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染，感染性肺炎和尿路感染。
T0703	Flavoxate hydrochloride Flavoxate HCl,盐酸黄酮哌酯,NSC-114649,DW61,Rec-7-0040	AChR	Neuroscience
	Flavoxate hydrochloride (DW61) 是一种毒蕈碱受体 AChR 拮抗剂， IC50为 12.2 μM。
T29687	Afacifenacin Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986	AChR	Neuroscience
	Afacifenacin (SMP-986) fumarate 是一种 M3 毒蕈碱受体选择性拮抗剂，可用于研究缺血性心脏病，尿失禁和膀胱炎和其他疾病。
T0400	Nitroxoline 5-Nitro-8-quinolinol,8-Hydroxy-5-nitroquinoline,5-Nitro-8-hydroxyquinoline,5-nitroquinolin-8-ol,硝羟喹啉	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Nitroxoline (5-nitroquinolin-8-ol) 是一种抗生素，防治生物膜感染。它通过从生物膜基质螯合Fe2+和Zn2+离子而发挥作用。
T11305	Flurofamide	Others	Others
	Flurofamide 是一种细菌尿素酶抑制剂，在感染性尿路结石方面有研究的价值。
T1534	Darifenacin hydrobromide 氢溴酸达非那新,Darifenacin HBr,UK-88525	AChR	Neuroscience
	Darifenacin hydrobromide (UK-88525) 是一种选择性 M3 蕈毒碱受体拮抗剂，pKi 为 8.9。
T4273	Furagin F-35,Akritoin,Furazidine,NF-416,呋喃烯啶,Furazidin	Antibacterial	Microbiology/Virology
	Furagin (Furazidine) 是 nitrofurantoin 类似物，有抗菌活性，用于尿路感染。
T22316	Doxazosin UK 33274,多沙唑嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Doxazosin (UK 33274) 是选择性的拮抗突触后的α1肾上腺素受体。
TP1819L	Substance P 1-9 aceate	Neurotensin Receptor	GPCR/G Protein
	Substance P 1-9 aceate 是九肽，可减少豚鼠回肠和膀胱对 P 物质的失活。
T2184	Sulfachloropyridazine Sulfachlorpyridazine,磺胺二甲基嘧啶	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfachloropyridazine (Sulfachlorpyridazine) 是一种广谱磺酰胺，抑制革兰氏阳性和革兰氏阴性好氧细菌的生长。
T0026	Sulfalene 磺胺林,Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene	Antibacterial; Antibiotic; Parasite; Autophagy	Autophagy; Microbiology/Virology
	Sulfalene (SMP2) 是一种长效磺胺类抗生素，用于治疗慢性支气管炎、尿路感染和疟疾。
T9420	prifinium bromide	Others	Others
	Prifinium bromide 是抗胆碱能试剂，能够改善痉挛，具有止吐效果。
T28257L	(-)-OPC-51803	AChR	Neuroscience
	(-)-OPC-51803 是一种抗利尿激素 V2受体激动剂，可用于夜尿症和尿失禁的治疗。
T6349L	Sitafloxacin DU-6859A,Sitafloxacin anhydrous,DU 6859,DU6859,DU-6859,DU 6859A,DU6859A	Antibiotic	Microbiology/Virology
	Sitafloxacin (Sitafloxacin anhydrous) 是一种具有口服活性的氟喹诺酮类抗生素，具有广谱的抗菌活性。Sitafloxacin 可用于研究呼吸道感染和尿路感染。
T0111	Solifenacin succinate YM905,索非那新琥珀酸盐	AChR	Neuroscience
	Solifenacin succinate (YM905) 是毒蕈碱受体拮抗剂，对 M1、M2和M3受体的pKi 值分别为 7.6、6.9 和 8.0。
T0087L	Sulfacetamide sodium Sulamyd sodium,磺乙酰胺钠盐,磺胺醋酰钠	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Sulfacetamide sodium (Sulamyd sodium) 是磺胺类抗感染剂，可局部用于口服治疗尿路感染和皮肤感染。
T28257	OPC-51803 SOU-003,SOU 003,SOU003,OPC51803,OPC 51803	Vasopressin Receptor	GPCR/G Protein
	OPC-51803是一种可口服的非肽加压素（AVP）V（2）受体选择性激动剂，可用于治疗尿失禁和夜尿。
T19794	Temafloxacin 替马沙星,Omniflox	Antibiotic	Microbiology/Virology
	Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂，对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。
T35851	Etzadroxil Ethyl 2-Ethylbutyrate	Antibacterial	Microbiology/Virology
	Etzadroxil (Ethyl 2-Ethylbutyrate) 是一种可口服且具有挥发性的酯化物。Etzadroxil 具有广谱的抗菌活性，可用于治疗由多重耐药细菌引起的尿路感染。
T0170	Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) phosphonomycin calcium,Fosfomycin calcium,磷霉素钙,phosphomycin calcium	Antibiotic	Microbiology/Virology
	Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) (phosphonomycin calcium)是一种抗生素，用于治疗敏感菌株引起的尿路感染和肠道感染。
T1460	Dicyclomine hydrochloride	AChR	Neuroscience
	Dicyclomine hydrochloride 是口服活性毒蕈碱胆碱能受体拮抗剂。它是一种抗痉挛试剂，在体内可缓解胃肠道平滑肌痉挛。它对 M1 受体亚型和 M2 受体亚型，Ki 分别为5.1和54.6nM，在刷状缘膜和基底质膜中均表现出较高的亲和力。
T8802	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur	Serine Protease	Proteases/Proteasome
	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) 是胰蛋白酶抑制剂（人尿 urinastatin protein moiety），作为尿胰蛋白酶抑制剂（UTI），是一种从健康人尿液中分离或合成产生的糖蛋白。
T1475	Fesoterodine fumarate Toviaz,SPM 907,富马酸非索罗定	AChR	Neuroscience
	Fesoterodine fumarate (Toviaz) 是可口服的，非亚型选择性的竞争性毒蕈碱受体拮抗剂，用于膀胱过度活动症，对 M1、M2、M3、M4 和 M5 受体的pKi 值分别为 8.0、7.7、7.4、7.3 和 7.5。

化合物

Urinary Incontinence-Targeting Compound 1

Cat.No: T19417

Target: Others

Urinary Trypsin Inhibitor Fragment

Cat.No: T76240

Cat.No: T1049L

Synonym: Oxytrol,奥昔布宁,Ditropan,Oxibutyninum

Target: Potassium Channel, AChR

Oxybutynin chloride

Cat.No: T1049

Synonym: Oxybutynin hydrochloride,盐酸奥昔布宁,Oxybutynin HCl

Target: Potassium Channel, AChR

Methenamine Hippurate

Cat.No: T8365

Target: Antibacterial

SulfadiMethoxine sodium

Cat.No: T8133

Target: Anti-infection, Antibacterial, Antibiotic

Cat.No: T1444

Synonym: 洛美沙星,SC47111A

Target: Topoisomerase, Antibacterial, Antibiotic

Sulfadimethoxine

Cat.No: T1078

Synonym: Sulphadimethoxine,磺胺二甲氧嗪

Target: Antibacterial, Antibiotic

Bethanechol chloride

Cat.No: T3126

Synonym: (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride

Target: AChR

Cat.No: T16789

Synonym: 罗索沙星,Acrosoxacin

Target: Antibacterial, Antibiotic

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Cat.No: T5513

Target: P2X Receptor

Cat.No: T5521

Synonym: U-54461,溴匹立明

Target: TLR

Cat.No: T0748

Synonym: 5-Methoxysulfadiazine,Sulfametoxydiazine,磺胺对甲氧嘧啶

Target: DHFR, Antibacterial, Antibiotic

Propiverine hydrochloride

Cat.No: T5023

Target: Others, Calcium Channel, AChR

Cat.No: T10952

Synonym: 达布扎琼,Ro 115-1240

Target: Apoptosis, Adrenergic Receptor

Cat.No: T0274

Synonym: 西诺沙星,Compound 64716

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0396

Synonym: 吡哌酸,Acido pipemidico

Target: Antibacterial, Antibiotic

Cefmetazole sodium

Cat.No: T1070

Synonym: 头孢美唑钠,Sodium cefmetazole

Target: Antibacterial, Antibiotic

Trospium chloride

Cat.No: T1472

Synonym: Spasmex,Sanctura,曲司氯铵,曲司氯胺

Target: AChR

Monobenzyl phthalate

Cat.No: T0601

Synonym: 邻苯二甲酸单苄酯,Phthalic Acid Monobenzyl Ester

Target: Others, Endogenous Metabolite

Lomefloxacin hydrochloride

Cat.No: T1625

Synonym: Lomefloxacin HCl,盐酸洛美沙星,Okacyn,Maxaquin

Target: Topoisomerase, Antibacterial, Antibiotic

Sitafloxacin Hydrate

Cat.No: T6349

Synonym: 西他沙星水合物,DU-6859a,DU6859a hydrate

Target: Antibacterial, Antibiotic

Sulfamethoxazole sodium

Cat.No: T8139

Synonym: 新诺明钠,Ro 4-2130 sodium,磺胺甲恶唑钠

Target: Others, Antibacterial, Antibiotic

Tolterodine tartrate

Cat.No: T0099

Synonym: Detrol LA,PNU-200583E,Kabi-2234,酒石酸托特罗定

Target: AChR

Cat.No: T1233

Synonym: Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox

Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T1504

Synonym: 西洛多辛,KAD 3213,KMD 3213

Target: Adrenergic Receptor

Cat.No: T5189

Synonym: PTK 0796,Amadacycline

Target: ribosome, Antibacterial, Antibiotic

Flavoxate hydrochloride

Cat.No: T0703

Synonym: Flavoxate HCl,盐酸黄酮哌酯,NSC-114649,DW61,Rec-7-0040

Target: AChR

Cat.No: T29687

Synonym: Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986

Target: AChR

Cat.No: T0400

Synonym: 5-Nitro-8-quinolinol,8-Hydroxy-5-nitroquinoline,5-Nitro-8-hydroxyquinoline,5-nitroquinolin-8-ol,硝羟喹啉

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T11305

Target: Others

Darifenacin hydrobromide

Cat.No: T1534

Synonym: 氢溴酸达非那新,Darifenacin HBr,UK-88525

Target: AChR

Cat.No: T4273

Synonym: F-35,Akritoin,Furazidine,NF-416,呋喃烯啶,Furazidin

Target: Antibacterial

Cat.No: T22316

Synonym: UK 33274,多沙唑嗪

Target: Adrenergic Receptor

Substance P 1-9 aceate

Cat.No: TP1819L

Target: Neurotensin Receptor

Sulfachloropyridazine

Cat.No: T2184

Synonym: Sulfachlorpyridazine,磺胺二甲基嘧啶

Target: Antibacterial, Antibiotic

Cat.No: T0026

Synonym: 磺胺林,Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene

Target: Antibacterial, Antibiotic, Parasite, Autophagy

prifinium bromide

Cat.No: T9420

Target: Others

Cat.No: T28257L

Target: AChR

Cat.No: T6349L

Synonym: DU-6859A,Sitafloxacin anhydrous,DU 6859,DU6859,DU-6859,DU 6859A,DU6859A

Target: Antibiotic

Solifenacin succinate

Cat.No: T0111

Synonym: YM905,索非那新琥珀酸盐

Target: AChR

Sulfacetamide sodium

Cat.No: T0087L

Synonym: Sulamyd sodium,磺乙酰胺钠盐,磺胺醋酰钠

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T28257

Synonym: SOU-003,SOU 003,SOU003,OPC51803,OPC 51803

Target: Vasopressin Receptor

Cat.No: T19794

Synonym: 替马沙星,Omniflox

Target: Antibiotic

Cat.No: T35851

Synonym: Ethyl 2-Ethylbutyrate

Target: Antibacterial

Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI)

Cat.No: T0170

Synonym: phosphonomycin calcium,Fosfomycin calcium,磷霉素钙,phosphomycin calcium

Target: Antibiotic

Dicyclomine hydrochloride

Cat.No: T1460

Target: AChR

2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-

Cat.No: T8802

Synonym: 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur

Target: Serine Protease

Fesoterodine fumarate

Cat.No: T1475

Synonym: Toviaz,SPM 907,富马酸非索罗定

Target: AChR

Cat. No.	Product Name	Target	Signaling Pathways
T10815	Cinnamoylglycine	Endogenous Metabolite	Metabolism
	Cinnamoylglycine 是肉桂酸和的甘氨酸结合物，是人体尿液代谢物。它被用作的尿液标志物，能够作为在抗生素研究期之后定殖耐药性的标志物。
T10021	1-Methylxanthine	Endogenous Metabolite	Metabolism
	1-Methylxanthine 是咖啡因衍生物，是咖啡因和茶碱 (1,3-二甲基黄嘌呤，TP) 在人体尿代谢产物，能够提高肿瘤细胞的放射敏感性。
T9599	3,4,5-Trimethoxybenzaldehyde	Anti-infection; Antibacterial	Microbiology/Virology
	3,4,5-Trimethoxybenzaldehyde 是合成各种药物，特别是治疗细菌感染的甲氧苄啶的中间体，它有抗念珠菌功效并抑制粘附和生物膜。
T8126	Cefodizime Sodium	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Cefodizime sodium 是一种头孢菌素抗生素，具有抗菌活性。它对肾脏没有毒性，具有良好的耐受性和免疫调节活性，可研究呼吸道和泌尿道的严重感染。
T1313	Nitrofurantoin Furadantine,呋喃妥因,Macrodantin,Furadonine	Antibacterial; Antibiotic	Microbiology/Virology
	Nitrofurantoin (Furadantine) 是一种具有口服活性的广谱内酰胺酶抗菌剂。它是一种抗生素，可研究尿路感染。
T0613	3-Hydroxyisovaleric acid β-羟基异戊酸,Beta-Hydroxyisovaleric acid	Others; Endogenous Metabolite	Metabolism; Others
	3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) 是尿液中排泄的内源性代谢产物，可作为生物素缺乏的早期和敏感指标。
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。
T4456	N4-Acetylcytidine N4-乙酰胞苷,N-Acetylcytidine	Others; Endogenous Metabolite	Metabolism; Others
	N4-Acetylcytidine (N-Acetylcytidine) 是内源性代谢产物的一种。
TQ0193	N2,N2-Dimethylguanosine N2,N2-二甲基鸟苷	Endogenous Metabolite	Metabolism
	N2,N2-Dimethylguanosine 是尿核苷，是 tRNA 的初级代谢产物。
TN7107	S-(2-Carboxypropyl)cysteine	Endogenous Metabolite	Metabolism
	S-(2-Carboxypropyl)cysteine 是 S-(2-Carboxypropyl)glutathione 的尿代谢产物。
T7154	trans-trans-Muconic acid	Endogenous Metabolite	Metabolism
	trans-trans-Muconic acid 是苯的尿代谢物，能够被用作人体暴露于苯的生物标志物。
T0543	7-Methylxanthine Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤	Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Adenosine Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	7-Methylxanthine 是一种黄嘌呤的甲基衍生物，是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。
T4107	4-Pyridoxic Acid 4-吡哆酸,Pyridoxic Acid,4-Pyridoxinsaeure	Endogenous Metabolite	Metabolism
	4-Pyridoxic Acid (4-Pyridoxinsaeure) 是一种维生素B6的分解代谢产物，从尿液中分泌得到。
T4853	TRIA-662 3-Carbamoyl-1-methylpyridinium Chloride,3-氨基甲酰-1-甲基氯化吡啶,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate	Others; Endogenous Metabolite	Metabolism; Others
	TRIA-662 (Nicotinamide Chloromethylate) 是内源性代谢产物的一种。
T3A2467	Allocryptopine Thalictrimine,Fagarine I,别隐品碱	Potassium Channel	Membrane transporter/Ion channel
	Allocryptopine (Thalictrimine) 是一种延胡索乙素的衍生物，提取自Corydalis decumbens。Allocryptopine 具有抗心律失常作用，能有效阻断hERG 电流。
T5984	Indole-3-carboxylic acid 3-Indoleformic acid,3-吲哚甲酸	Endogenous Metabolite	Metabolism
	Indole-3-carboxylic acid (3-Indoleformic acid) 是尿吲哚色氨酸代谢物，在肝病患者中浓度会升高。
T4816	6-Hydroxynicotinic acid 6-Hydroxypyridine-3-carboxylic acid,6-羟基烟酸,2-Hydroxy-5-pyridinecarboxylic acid	Others; Endogenous Metabolite	Metabolism; Others
	6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) 用于核磁共振波谱或气相色谱-质谱法诊断尿路感染中的铜绿假单胞菌。在引起尿液感染的常见细菌中，只有铜绿假单胞菌从烟酸中产生6-羟基烟酸。
T8075	1,3-Dimethyluric acid	Endogenous Metabolite	Metabolism
	1,3-Dimethyluric acid 是尿路结石中的嘌呤成分之一，是一种人体茶碱代谢的产物。
T16542	Piromidic acid 吡咯酸,吡乙酸三氮萘	Antibacterial; Antibiotic	Microbiology/Virology
	Piromidic acid 是一种抗菌剂。它对革兰氏阴性菌和葡萄球菌具有活性，可研究肠道，泌尿和胆道感染。
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
T0738	Urea 尿素,Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide	Others; DHFR; Wnt/beta-catenin; Arginase; Endogenous Metabolite; Carbonic Anhydrase	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others; Stem Cells
	Urea (Carbonyldiamide) 在肝脏中由氨基酸脱氨产生的氨形成。它是蛋白质分解代谢的主要终代谢产物。
T1571	Estriol NSC-12169,Oestriol,雌三醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite	Endocrinology/Hormones; Immunology/Inflammation; Metabolism
	Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。
T1630	Tiopronin Thiopronine,硫普罗宁,Acadione,Captimer	ROS	Immunology/Inflammation
	Tiopronin (Acadione) 是可扩散的抗氧化剂，是重金属中毒的解毒剂和辐射防护剂。它可控制胱氨酸沉淀和排泄的速度，有用于胱氨酸尿症、类风湿性关节炎和肝病的研究潜力。
T5275	2,5-Furandicarboxylic acid Dehydromucic Acid,2,5-Dicarboxyfuran,2,5-呋喃二甲酸	Others; Endogenous Metabolite	Metabolism; Others
	2,5-Furandicarboxylic acid (Dehydromucic Acid) 是重要的能够再生生物技术基础，能够在人类尿液中检测到，在聚酯生产中能够作为对苯二甲酸的环保替代品。
T0983	Penicillamine 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine	Antibiotic	Microbiology/Virology
	Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
T5231	2-Methylsuccinic acid Pyrotartaric Acid,Methylbutanedioic acid,甲基丁二酸	Others; Endogenous Metabolite	Metabolism; Others
	2-Methylsuccinic acid (Pyrotartaric Acid) 是乙基丙二酸脑病的主要生化指标，是人体液中的正常代谢物。
T5309	Dimethylamine hydrochloride N,N-Dimethylamine,二甲胺盐酸盐	Others	Others
	Dimethylamine hydrochloride (N,N-Dimethylamine) 大量存在于人类尿液中。
T5246	Trans-2-butene-1,4-dicarboxylic acid trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid,反式-2-丁烯-1,4-二甲酸	Others; Endogenous Metabolite	Metabolism; Others
	Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) 是内源性代谢产物的一种。
T6S0119	Dauricine 蝙蝠葛碱	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	Dauricine 是存在于北豆根粉末中的一种双苯异喹啉生物碱，具有抗炎活性。它通过抑制NF-κB 激活，剂量依赖性地抑制结肠癌细胞的增值和侵袭，并诱导凋亡。
T37508	Meconin	Endogenous Metabolite	Metabolism
	Meconine 是一种人内源性代谢产物。
T4716	Pyrrole-2-carboxylic acid 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite	Metabolism
	Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类，从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
T5250	Levoglucosan 1,6-anhydro-b-D-Glucose,1,6-脱水-β-D-葡萄糖	Others; Endogenous Metabolite	Metabolism; Others
	Levoglucosan (1,6-anhydro-b-D-Glucose) 是一种无水己糖，是 β -D-葡萄糖的 1,6-无水衍生物。它是由碳水化合物，如淀粉和纤维素的热解形成的。左旋葡聚糖还可用于手性聚合物如不可水解葡萄糖聚合物的合成。左旋葡聚糖也可以通过糖的焦糖化产生。食用焦糖或含焦糖的甜食可导致尿中左旋葡聚糖水平短期增加5倍(从20 μm /mM肌酐增加到100 μm /mM肌酐)。
T19576	Tetrahydrocortisone	Others	Others
	Tetrahydrocortisone, a stress-induced hormone and a urinary metabolite of Cortisone, originates from the reduction of Cortisone facilitated by 5-reductase.
T40381	2,8-Dihydroxyadenine	Others	Others
	2,8-Dihydroxyadenine, an endogenous metabolite, can induce the generation of urinary crystals and nephrolithiasis. Moreover, 2,8-Dihydroxyadenine serves as a diagnostic tool for detecting adenine phosphoribosyltransferase (APRT) deficiency.
T15011	Creatine riboside	Others	Others
	Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.
T36472	Tetrahydro-11-deoxy Cortisol	Others	Others
	Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.
T13978	(S)-3,4-Dihydroxybutyric acid	Others	Others
	(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.
T17057	Tetrahydrocortisol	Others	Others
	The urinary Tetrahydrocortisol/Tetrahydrocortisone ratio decreases with increasing 11β-hydroxysteroid dehydrogenase activity. Tetrahydrocortisol is cortisol metabolite.
TN6028	Gardneramine
	Gardneramine has a mild central depressive effect. Gardneramine and hirsutine show a local anesthetic action, they also can inhibit the ganglionic transmission of the dog urinary bladder and that the blockade of the nicotinic receptor plays a main role.
T38954	L-Glyceric acid sodium	Others	Others
	L-Glyceric acid sodium is a urinary metabolite predominantly found in individuals with the rare inherited metabolic disorder, L-glyceric aciduria. This compound serves as a diagnostic tool for identifying primary hyperoxaluria type 2 (PH2) and can be used to differentiate between PH1 and PH2 based on its excretion pattern.
T81117	Spilanthol
	Spilanthol为一具有多种生物活性的化合物，包括镇痛、神经保护、抗氧化、抗诱变、抗癌、抗炎、抗菌以及杀虫作用。该化合物能够通过诱导cAMP抑制尿浓缩的负调节机制，且可作为利尿剂研究的候选物。
T37710	5-Hydroxyoxindole	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	5-Hydroxyoxindole 是尿酸的一种结构类似物，具有脂质过氧化抑制活性和自由基 DPPH 清除活性，可用于氧化应激介导的疾病的研究。
TN4382	Kazinol A	AMPK; mTOR	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M against XOD. Kazinol A may be a candidate for the development of effective anti-cancer drug on h

天然产物

Cinnamoylglycine

Cat.No: T10815

Target: Endogenous Metabolite

1-Methylxanthine

Cat.No: T10021

Target: Endogenous Metabolite

3,4,5-Trimethoxybenzaldehyde

Cat.No: T9599

Target: Anti-infection, Antibacterial

Cefodizime Sodium

Cat.No: T8126

Target: Others, Antibacterial, Antibiotic

Cat.No: T1313

Synonym: Furadantine,呋喃妥因,Macrodantin,Furadonine

Target: Antibacterial, Antibiotic

3-Hydroxyisovaleric acid

Cat.No: T0613

Synonym: β-羟基异戊酸,Beta-Hydroxyisovaleric acid

Target: Others, Endogenous Metabolite

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

N4-Acetylcytidine

Cat.No: T4456

Synonym: N4-乙酰胞苷,N-Acetylcytidine

Target: Others, Endogenous Metabolite

N2,N2-Dimethylguanosine

Cat.No: TQ0193

Synonym: N2,N2-二甲基鸟苷

Target: Endogenous Metabolite

S-(2-Carboxypropyl)cysteine

Cat.No: TN7107

Target: Endogenous Metabolite

trans-trans-Muconic acid

Cat.No: T7154

Target: Endogenous Metabolite

7-Methylxanthine

Cat.No: T0543

Synonym: Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Adenosine Receptor

4-Pyridoxic Acid

Cat.No: T4107

Synonym: 4-吡哆酸,Pyridoxic Acid,4-Pyridoxinsaeure

Target: Endogenous Metabolite

Cat.No: T4853

Synonym: 3-Carbamoyl-1-methylpyridinium Chloride,3-氨基甲酰-1-甲基氯化吡啶,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate

Target: Others, Endogenous Metabolite

Cat.No: T3A2467

Synonym: Thalictrimine,Fagarine I,别隐品碱

Target: Potassium Channel

Indole-3-carboxylic acid

Cat.No: T5984

Synonym: 3-Indoleformic acid,3-吲哚甲酸

Target: Endogenous Metabolite

6-Hydroxynicotinic acid

Cat.No: T4816

Synonym: 6-Hydroxypyridine-3-carboxylic acid,6-羟基烟酸,2-Hydroxy-5-pyridinecarboxylic acid

Target: Others, Endogenous Metabolite

1,3-Dimethyluric acid

Cat.No: T8075

Target: Endogenous Metabolite

Cat.No: T16542

Synonym: 吡咯酸,吡乙酸三氮萘

Target: Antibacterial, Antibiotic

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0738

Synonym: 尿素,Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide

Target: Others, DHFR, Wnt/beta-catenin, Arginase, Endogenous Metabolite, Carbonic Anhydrase

Cat.No: T1571

Synonym: NSC-12169,Oestriol,雌三醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite

Cat.No: T1630

Synonym: Thiopronine,硫普罗宁,Acadione,Captimer

Target: ROS

2,5-Furandicarboxylic acid

Cat.No: T5275

Synonym: Dehydromucic Acid,2,5-Dicarboxyfuran,2,5-呋喃二甲酸

Target: Others, Endogenous Metabolite

Cat.No: T0983

Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Target: Antibiotic

2-Methylsuccinic acid

Cat.No: T5231

Synonym: Pyrotartaric Acid,Methylbutanedioic acid,甲基丁二酸

Target: Others, Endogenous Metabolite

Dimethylamine hydrochloride

Cat.No: T5309

Synonym: N,N-Dimethylamine,二甲胺盐酸盐

Target: Others

Trans-2-butene-1,4-dicarboxylic acid

Cat.No: T5246

Synonym: trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid,反式-2-丁烯-1,4-二甲酸

Target: Others, Endogenous Metabolite

Cat.No: T6S0119

Synonym: 蝙蝠葛碱

Target: Apoptosis, Others, NF-κB

Cat.No: T37508

Target: Endogenous Metabolite

Pyrrole-2-carboxylic acid

Cat.No: T4716

Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

Cat.No: T5250

Synonym: 1,6-anhydro-b-D-Glucose,1,6-脱水-β-D-葡萄糖

Target: Others, Endogenous Metabolite

Tetrahydrocortisone

Cat.No: T19576

Target: Others

2,8-Dihydroxyadenine

Cat.No: T40381

Target: Others

Creatine riboside

Cat.No: T15011

Target: Others

Tetrahydro-11-deoxy Cortisol

Cat.No: T36472

Target: Others

(S)-3,4-Dihydroxybutyric acid

Cat.No: T13978

Target: Others

Tetrahydrocortisol

Cat.No: T17057

Target: Others

Cat.No: TN6028

L-Glyceric acid sodium

Cat.No: T38954

Target: Others

Cat.No: T81117

5-Hydroxyoxindole

Cat.No: T37710

Target: Reactive Oxygen Species

Cat.No: TN4382

Target: AMPK, mTOR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02965	Uromodulin/Umod Protein, Mouse, Recombinant (His) Uromodulin,Umod,Tamm-Horsfall urinary glycoprotein	Mouse	P. pastoris (Yeast)
	Uromodulin/Umod Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 64.2 kDa and the accession number is Q91X17.
TMPH-02775	Mup11 Protein, Mouse, Recombinant (His) Mup11,Major urinary protein 11	Mouse	E. coli
	Mup11 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-02776	Mup2 Protein, Mouse, Recombinant (His) Major urinary protein 2,Mup2	Mouse	P. pastoris (Yeast)
	Mup2 Protein, Mouse, Recombinant (His) is expressed in Yeast.
TMPH-02777	Mup6 Protein, Mouse, Recombinant (His & SUMO) Major urinary protein 6,Mup6,Alpha-2U-globulin,Grou...	Mouse	E. coli
	Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. Mup6 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is P02762.
TMPH-02067	SLURP1 Protein, Human, Recombinant (His) ARS(component B)-81/S,ARS component B,SLURP1,Secreted Ly-6/u...	Human	E. coli
	SLURP1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated Polymorphic epithelial mucin,KL-6,Cancer antigen 15-3,PEMT,P...	Human	HEK293 Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane ...
TMPH-01705	Mucin-1/MUC1 Protein, Human, Recombinant (Isoform 8, His) Peanut-reactive urinary mucin,Isoform 8 of Mucin-1,...	Human	E. coli
	Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His) Protein C inhibitor,Plasminogen activator inhibitor 3,Serpin...	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple...
TMPH-02046	Ribonuclease 7 Protein, Human, Recombinant (His) RNASE7,Skin-derived antimicrobial protein 2,Ribonuclease 7	Human	E. coli
	Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. Ribonuclease 7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted...
TMPK-00967	DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) CMD1BB,Desmoglein-2,ARVC10,CDHF5,MGC117037,MGC117036,HDGC,DS...	Human	HEK293 Cells
	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mo...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPK-00736	DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His) MGC117036,HDGC,Desmoglein-2,CDHF5,DSG2,MGC117037,ARVC10,CMD1...	Mouse	HEK293 Cells
	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mo...
TMPH-01508	HABP2 Protein, Human, Recombinant (His & SUMO) Hepatocyte growth factor activator-like protein,Factor VII-a...	Human	E. coli
	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulat...
TMPY-04171	MFAP3 Protein, Human, Recombinant (hFc) microfibrillar-associated protein 3	Human	HEK293 Cells
	MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found to be located on chromosome 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2, which has been linked to congenital contractural arachnodactyly. MFAP3 is widely expressed in the placenta, urinary bladder, and other tissues. It does not appear to share homo...
TMPJ-01116	HABP2 Protein, Human, Recombinant (His) Factor seven-activating protease,Factor VII-activating prote...	Human	HEK293 Cells
	Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His) Plasminogen Activator Inhibitor 3,Acrosomal Serine Protease ...	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o...
TMPY-02220	HRAS Protein, Human, Recombinant (His) HAMSV,Harvey rat sarcoma viral oncogene homolog,C-H-RAS,C-HA...	Human	Baculovirus Insect Cells
	HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Defects in HRAS are the cause of faciocutaneoskeletal syndrome (FCSS). FCSS is a rare condition characterized by prenatally increase...

重组蛋白

Uromodulin/Umod Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02965

Species: Mouse

Expression System: P. pastoris (Yeast)

Mup11 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02775

Species: Mouse

Expression System: E. coli

Mup2 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02776

Species: Mouse

Expression System: P. pastoris (Yeast)

Mup6 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02777

Species: Mouse

Expression System: E. coli

SLURP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02067

Species: Human

Expression System: E. coli

Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

Cat.No: TMPJ-00155

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (Isoform 8, His)

Cat.No: TMPH-01705

Species: Human

Expression System: E. coli

Serpin A5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

Ribonuclease 7 Protein, Human, Recombinant (His)

Cat.No: TMPH-02046

Species: Human

Expression System: E. coli

DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00967

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00736

Species: Mouse

Expression System: HEK293 Cells

HABP2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01508

Species: Human

Expression System: E. coli

MFAP3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04171

Species: Human

Expression System: HEK293 Cells

HABP2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01116

Species: Human

Expression System: HEK293 Cells

Serpin A5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00490

Species: Human

Expression System: HEK293 Cells

HRAS Protein, Human, Recombinant (His)

Cat.No: TMPY-02220

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
T36055	Nitisinone-13C6 Nitisinone-13C6
	Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
TMIJ-0437	Sulfameter-d4
	Sulfameter-d4 是 Sulfameter 的氘代化合物。Sulfameter 的 CAS 号为 651-06-9。Sulfameter是一种长效磺胺类抗生素，具有抗菌活性。它可研究尿路感染和麻风病。
TMIH-0532	Sulfachloropyridazine-d4
	Sulfachloropyridazine-d4 是 Sulfachloropyridazine 的氘代化合物。Sulfachloropyridazine 的 CAS 号为 80-32-0。Sulfachloropyridazine 是一种广谱磺酰胺，抑制革兰氏阳性和革兰氏阴性好氧细菌的生长。
TMIJ-0035	16α-Hydroxy-17β-estradiol-2,4-d2
	16α-Hydroxy-17β-estradiol-2,4-d2 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。
TMID-0063	rac Bendroflumethiazide-d5
	rac Bendroflumethiazide-d5 是 rac Bendroflumethiazide 的氘代化合物。rac Bendroflumethiazide 的 CAS 号为 73-48-3。Bendroflumethiazide 是一种口服具有活性的利尿剂。它是一种抗高血压药。它对动脉高血压疾病具有潜在的研究价值。
T36537	Nitrofurantoin-13C3 Nitrofurantoin-13C3
	Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg/kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as ca...
TMID-0195	Levofloxacin-d8
	Levofloxacin-d8 是 Levofloxacin 的氘代化合物。Levofloxacin 的 CAS 号为 100986-85-4。Levofloxacin是合成的氟喹诺酮类抗生素，有抑制细菌DNA旋转酶的超螺旋活性的作用，能阻止DNA复制。
TMIJ-0158	Sitafloxacin-d4
	Sitafloxacin-d4 是 Sitafloxacin 的氘代化合物。Sitafloxacin 的 CAS 号为 127254-12-0。Sitafloxacin (Sitafloxacin anhydrous) 是一种具有口服活性的氟喹诺酮类抗生素，具有广谱的抗菌活性。Sitafloxacin 可用于研究呼吸道感染和尿路感染。
TMIH-0300	Levofloxacin-d3
	Levofloxacin-d3 是 Levofloxacin 的氘代化合物。Levofloxacin 的 CAS 号为 100986-85-4。Levofloxacin是合成的氟喹诺酮类抗生素，有抑制细菌DNA旋转酶的超螺旋活性的作用，能阻止DNA复制。
TMIJ-0235	rac-Tolterodine-d14 Tartrate
	rac-Tolterodine-d14 Tartrate 是 rac-Tolterodine Tartrate 的氘代化合物。rac-Tolterodine Tartrate 的 CAS 号为 124937-52-6。Tolterodine Tartrate 是毒蕈碱受体的有效拮抗剂。它在体内显示出对膀胱和唾液腺的选择性。
TMIJ-0280	Estriol-d3
	Estriol-d3 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。
T36021	Flumequine-13C3 Flumequine-13C3
	Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae(MICs = 1-100 μg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3In vivo, fl...
TMID-0096	P-CRESOL-d3 (METHYL-d3)
	P-CRESOL-d3 (METHYL-d3) 是 P-CRESOL 的氘代化合物。P-CRESOL 的 CAS 号为 106-44-5。p-Cresol 是一种部分亲脂性部分，在正常条件下与血浆蛋白（接近 100%）强烈结合。对甲酚通过结合代谢，主要是硫酸化和葡萄糖醛酸化，但未结合的对甲酚至少部分通过尿液去除。
T35698	Octanoic Acid-13C
	Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d...

同位素标记化合物

Nitisinone-13C6

Cat.No: T36055

Synonym: Nitisinone-13C6

Cat.No: TMIJ-0437

Sulfachloropyridazine-d4

Cat.No: TMIH-0532

16α-Hydroxy-17β-estradiol-2,4-d2

Cat.No: TMIJ-0035

rac Bendroflumethiazide-d5

Cat.No: TMID-0063

Nitrofurantoin-13C3

Cat.No: T36537

Synonym: Nitrofurantoin-13C3

Levofloxacin-d8

Cat.No: TMID-0195

Sitafloxacin-d4

Cat.No: TMIJ-0158

Levofloxacin-d3

Cat.No: TMIH-0300

rac-Tolterodine-d14 Tartrate

Cat.No: TMIJ-0235

Cat.No: TMIJ-0280

Flumequine-13C3

Cat.No: T36021

Synonym: Flumequine-13C3

P-CRESOL-d3 (METHYL-d3)

Cat.No: TMID-0096

Octanoic Acid-13C

Cat.No: T35698

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