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TMPY-04180
|
PfLDH Protein, P. falciparum, Recombinant (His)
PfLDH,L-lactate dehydrogenase
|
P. falciparum
|
E. coli
|
|
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy. |
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TMPY-02204
|
LBP Protein, Human, Recombinant (His)
BPIFD2,lipopolysaccharide binding protein
|
Human
|
HEK293 Cells
|
|
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end... |
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TMPH-01394
|
GRIN1 Protein, Human, Recombinant (His)
N-methyl-D-aspartate receptor subunit NR1,Glutamate [NMDA] r...
|
Human
|
E. coli
|
|
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. GRIN1 Protein, Human, Recombinant (His)... |
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TMPH-02582
|
CELA2A Protein, Mouse, Recombinant (His)
Elastase-2A,ELA2A,CELA2A,Chymotrypsin-like elastase family m...
|
Mouse
|
E. coli
|
|
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.7 kDa and the accession number is P05208. |
|
TMPH-02956
|
TNNI1 Protein, Mouse, Recombinant (Flag & His & Myc)
Troponin I, slow skeletal muscle,Tnni1,Troponin I, slow-twit...
|
Mouse
|
E. coli
|
|
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TNNI1 Protein, Mouse, Recombinant (Flag & His & Myc) is expressed in E. coli expression system with N-10xHis-Flag and C-Myc tag. The predicted molecular weight is 29.6 kDa and the accession number is Q9WUZ5. |
|
TMPH-02955
|
TNNI2 Protein, Mouse, Recombinant (His & Myc)
Tnni2,Troponin I, fast skeletal muscle,Troponin I, fast-twit...
|
Mouse
|
E. coli
|
|
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TNNI2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P13412. |
|
TMPH-00307
|
TnTf Protein, Bovine, Recombinant (His & Myc)
Tnnt3,Troponin T, fast skeletal muscle
|
Bovine
|
E. coli
|
|
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TnTf Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.0 kDa and the accession number is Q8MKI3. |
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TMPH-03393
|
TnTc Protein, Rat, Recombinant (His)
Troponin T, cardiac muscle,Cardiac muscle troponin T,Tnnt2
|
Rat
|
E. coli
|
|
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TnTc Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 41.6 kDa and the accession number is P50753. |
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TMPH-02954
|
TNNI3 Protein, Mouse, Recombinant (His & SUMO)
Cardiac troponin I,Troponin I, cardiac muscle,Tnni3
|
Mouse
|
E. coli
|
|
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TNNI3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 40.1 kDa and the accession number is P48787. |
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TMPH-01094
|
CELA2A Protein, Human, Recombinant (His)
Chymotrypsin-like elastase family member 2A,CELA2A,ELA2A,Ela...
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Human
|
P. pastoris (Yeast)
|
|
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P08217. |
|
TMPH-01093
|
CELA2A Protein, Human, Recombinant (E. coli, His)
Elastase-2A,CELA2A,Chymotrypsin-like elastase family member ...
|
Human
|
E. coli
|
|
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P08217. |
|
TMPK-00516
|
BST1 Protein, Cynomolgus, Recombinant (His)
Bp-3,CD157,Bst1,BST-1,Ly65,Bp3,Antigen BP3
|
Cynomolgus
|
HEK293 Cells
|
|
BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon exposure to exogenous sphingosine. sphingoid base metabolism is similar in all eukaryotes and suggests that yeast genetics may be useful in the isolation and identification of other genes involved in sphingolipid signaling and metabolism. |
|
TMPK-01137
|
FAM3D Protein, Human, Recombinant (hFc)
OIT1,EF7,FAM3D
|
Human
|
HEK293 Cells
|
|
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity t... |
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TMPK-00751
|
FSTL3 Protein, Human, Recombinant (His)
FSTL3,FLRGFSRP,Follistatin-like 3,FLRG
|
Human
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HEK293 Cells
|
|
Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both human chronic kidney disease (CKD) and acute kidney dysfunction (AKD). Furthermore, mFSTL3 expression was analysed in insulin-sensitive tissues in a mouse model of CKD. |
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TMPY-03329
|
DPEP1 Protein, Human, Recombinant (His)
MBD1,dipeptidase 1,MDP,RDP
|
Human
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HEK293 Cells
|
|
Dehydropeptidase-I, also known as DPEP1, is a kidney membrane enzyme. Its expression in normal colonic mucosa is very low, but it is highly expressed in colorectal adenoma and cancer specimens and is negatively correlated with parameters of pathological aggressiveness and poor prognosis. The overexpression of DPEP1 suppressed tumor cells invasiveness and increased sensitivity to chemotherapeutic agent Gemcitabine. Growth factor EGF treatment decreased DPEP1 expression. Dehydropeptidase-I m... |
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TMPK-00410
|
AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UFO,AI32364...
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Human
|
HEK293 Cells
|
|
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec... |
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TMPK-00408
|
AXL Protein, Human, Recombinant (His & Avi), Biotinylated
AXL oncogene,EC 2.7.10.1,AI323647,Axl,JTK11,ARK,EC 2.7.10,UF...
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Human
|
HEK293 Cells
|
|
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi), Bio... |
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TMPK-00407
|
AXL Protein, Human, Recombinant (His & Avi)
AXL oncogene,Axl,EC 2.7.10.1,Tyro7,UFO,ARK,EC 2.7.10,AI32364...
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Human
|
HEK293 Cells
|
|
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi) is e... |
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TMPK-00472
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AXL Protein, Cynomolgus, Recombinant (His)
Tyro7,JTK11,AI323647,AXL oncogene,EC 2.7.10.1,EC 2.7.10,UFO,...
|
Cynomolgus
|
HEK293 Cells
|
|
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Cynomolgus, Recombinant (His) is ex... |
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TMPH-01368
|
GABRP Protein, Human, Recombinant (His)
GABRP,GABA(A) receptor subunit pi,Gamma-aminobutyric acid re...
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Human
|
E. coli
|
|
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. GABRP Protein, Human, Recombinant (His) is expressed in E. coli... |
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TMPJ-00922
|
DCK Protein, Human, Recombinant (His & T7)
DCK,Deoxycytidine Kinase
|
Human
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E. coli
|
|
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and c... |
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TMPK-00149
|
Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)
Fc-ε RI-α,Fc-epsilon RI-alpha,FCER1A,Fc-epsilon RI-α,FCE1A,F...
|
Human
|
HEK293 Cells
|
|
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic dis... |
|
TMPY-03047
|
Stathmin 1 Protein, Human, Recombinant (His)
SMN,OP18,stathmin 1,LAP18,C1orf215,PP17,Lag,PP19,PR22
|
Human
|
E. coli
|
|
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and prom... |
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TMPY-00055
|
LCAT Protein, Human, Recombinant (His)
lecithin-cholesterol acyltransferase
|
Human
|
HEK293 Cells
|
|
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport. Lecithin cholesterol acyltransferase (LCAT) plays a pivotal role in HDL metabolism.LCAT is intimately involved in HDL maturation an... |
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TMPY-02452
|
CMBL Protein, Human, Recombinant (His)
carboxymethylenebutenolidase homolog (Pseudomonas),JS-1
|
Human
|
E. coli
|
|
Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase, and carboxymethylene butenolide hydrolase, is a hydrolase specially belonging to the family of hydrolases. It maily acts on carboxylic ester bonds. CMBL is a human homolog of Pseudomonas dienelactone hydrolase involved in the bacterial halocatechol degradation pathway. The ubiquitous expression of human CMBL gene transcript in various tiss... |
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TMPJ-01415
|
ANGPTL4 Protein, Mouse, Recombinant (hFc)
Angptl4,HFARP,Fasting-induced adipose factor,Fiaf,Secreted p...
|
Mouse
|
HEK293 Cells
|
|
Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity... |
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TMPY-00410
|
EPHX2 Protein, Human, Recombinant (His)
SEH,CEH,epoxide hydrolase 2, cytoplasmic
|
Human
|
Baculovirus Insect Cells
|
|
Genetic variation in EPHX2 was significantly associated with risk of incident CHD in Caucasians, implicating EPHX2 as a potential cardiovascular disease-susceptibility gene. Single nucleotide polymorphisms (SNPs) in the human EPHX2 gene had been implicated in susceptibility to cardiovascular disease, including stroke. The human EPHX2 mutations may in part explain the genetic variability in sensitivity to ischemic brain injury and stroke outcome. Epoxide hydrolase is involved in metabolism of vas... |
|
TMPY-06836
|
NR3C1 Protein, Human, Recombinant (His)
GCCR,GRL,GR,nuclear receptor subfamily 3, group C, member 1 ...
|
Human
|
E. coli
|
|
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. NR3C1 is a transcriptional regulator of many drug-metabolizing enzymes and anti-inflammatory molecules. NR3C1 polymorphisms associate with obesi... |
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TMPY-04460
|
OXSR1 Protein, Human, Recombinant (GST)
OSR1,oxidative stress responsive 1
|
Human
|
Baculovirus Insect Cells
|
|
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. OXSR1 is a 58 kDa protein of 527 amino acids that is widely expressed in mammalian tissues and cell lines. The amino acid (aa) sequence of the predicted OXSR1 protein is 39% identical to that of human SOK1. Of... |
|
TMPY-02135
|
S100A16 Protein, Human, Recombinant
S100F,DT1P1A7,S100 calcium binding protein A16,MGC17528,AAG1...
|
Human
|
E. coli
|
|
S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has be... |
|
TMPY-01742
|
Acetylcholinesterase Protein, Mouse, Recombinant (His)
Acre,Chrne,acetylcholinesterase (Yt blood group)
|
Mouse
|
HEK293 Cells
|
|
Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role in nerve impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine (ACh). ACHE appears to be a potential therapeutic target at muscle injuries including organophosphate myopathy. It is an externally oriented membrane-bound enzyme and ... |
|
TMPY-04813
|
ACAT2 Protein, Rat, Recombinant (His)
acetyl-CoA acetyltransferase 2
|
Rat
|
E. coli
|
|
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio... |
|
TMPH-01503
|
Humanin Protein, Human, Recombinant (hFc)
MT-RNR2,Humanin,Humanin mitochondrial
|
Human
|
HEK293 Cells
|
|
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... |
|
TMPH-01502
|
Humanin Protein, Human, Recombinant (GST)
Humanin,Humanin mitochondrial,MT-RNR2
|
Human
|
E. coli
|
|
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... |
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