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Search Results for " radiation "

Targets Recommended: GPX

69

抑制剂 & 化合物

13

天然产物

3

化合物库

7

重组蛋白

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Cat. No.	Product Name
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L2190	抗肺癌化合物库		1702 compounds
	1702 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L2170	肿瘤免疫治疗小分子化合物库		449 compounds
	449 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；

化合物库

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

抗肺癌化合物库

Cat.No: L2190

Compounds: 1702

肿瘤免疫治疗小分子化合物库

Cat.No: L2170

Compounds: 449

Cat. No.	Product Name	Target	Signaling Pathways
T21899	Misonidazole SR-1354,SR1354,Ro 7-0582	GPX	oxidation-reduction
	Misonidazole 是一种缺氧肿瘤细胞放射增敏剂，具有抗菌活性。
T2046	Nimorazole Nimorazol,Nitrimidazine,尼莫唑,K-1900,Naxogin,尼莫拉唑	Others; Antibiotic; Parasite	Microbiology/Virology; Others
	Nimorazole (Nimorazol) 是一种 2-硝基咪唑，是一种低氧细胞辐射敏化剂。它具有抗感染，抗滴虫等原生动物的作用。它有头颈癌的研究潜力。
T1478	Ondansetron hydrochloride dihydrate 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ondansetron hydrochloride dihydrate (GR 38032) 是5- HT3受体拮抗剂，可治疗化疗后的恶心和呕吐，有抗焦虑和抗精神病作用。
T19957	Bismaleimide XU 292A,XU-292A,XU292A	Others	Others
	Bismaleimide (XU 292A) 具有抗热性、抗氧化性、抗辐射性，可用于制备电器绝缘材料、耐磨材料、增强塑料添加剂、砂轮粘结剂等。
T2068	(Rac)-LB-100	Phosphatase	Metabolism
	LB-100 是一种新型蛋白磷酸酶 2A (PP2A) 抑制剂，可使恶性脑膜瘤细胞对放射治疗效果敏感。
T20109	Cystamine dihydrochloride	Others	Others
	Cystamine dihydrochloride 是一种辐射防护剂。它还可以防止四氯化碳肝损伤。
T0698	Dioxybenzone UV-24,二羟苯宗,Benzophenone-8,2,2'-Dihydroxy-4-methoxybenzophenone,Dioxybenzon,Cyasorb UV 24,Advastab 47	Others	Others
	Dioxybenzone (Benzophenone-8) 是一种能够阻断 UVB 和短波 UVA 紫外线照射的有机试剂。
T15943	M443	p38 MAPK; Chk	Cell Cycle/Checkpoint; MAPK
	M443 是一种高效的 MRK 小分子抑制剂，抑制辐射诱导的 p38 和 Chk2 的激活，可用于研究癌症。
T12019	Methylproamine	Others	Others
	Methylproamine是一种与DNA结合的辐射保护剂，可以修复辐射诱导的短暂活性氧。
T6616	Ondansetron hydrochloride SN 307,盐酸昂丹司琼,帕罗西汀杂质A,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ondansetron hydrochloride (Zofran) 是5-HT3受体的拮抗剂，可用作化疗后止吐剂。
T2020	RGW 611	Others	Others
	RGW 611 是一种能够增强辐射且诱导缺氧 V79-379A 细胞死亡的吗啉衍生物。
TP1024	Rusalatide acetate (497221-38-2 free base) Rusalatide acetate,TP508 amide acetate	Others	Others
	Rusalatide acetate (TP508 amide acetate) 是一种再生肽，可诱导干细胞再生修复，保护隐窝完整性，减缓辐照引起的胃肠道损伤。
T31929	Giripladib PLA 695,PLA-695,PLA695	Phospholipase	Metabolism
	Giripladib (PLA695)(PLX-695)是一种cPLA2特异性抑制剂，可抑制辐射诱导的内皮细胞磷酸化ERK 和磷酸化Akt 的增加。
T7465	4-Methylbenzylidene camphor Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC	AChE	Neuroscience
	4-Methylbenzylidene camphor 是有机的樟脑衍生物，应用于化妆品行业，具有保护皮肤抵抗紫外线（特别是紫外线B 辐射）的能力。
T24184	Itasetron DAU6215CL,UNII-00S0D0OEKR,U-98079A,U 98079A,DAU 6215CL	5-HT Receptor	GPCR/G Protein; Neuroscience
	Itasetron (U 98079A) 是一种5-羟色胺3受体拮抗剂，可用于预防大鼠与年龄有关的记忆缺陷。Itasetron 在癌症化疗和放疗动物模型中的止吐活性，可用于研究健忘症。
T6970	RK33 RK-33,RK 33	COX	Immunology/Inflammation; Neuroscience
	RK33 (RK 33) 是 DDX3（一种 RNA 解旋酶）的一流小分子抑制剂，可导致 G1 细胞周期停滞，诱导细胞凋亡，并促进 DDX3 过表达细胞的辐射增敏。
T38681	P-SCN-Bn-DOTA	Others	Others
	p-SCN-Bn-DOTA 是一种螯合剂，可同时螯合放射性核素和连接单克隆抗体，可作为放射引导手术的示踪剂，可用于肿瘤的放射免疫研究。
T1110	Meclizine dihydrochloride Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪	Apoptosis; Histamine Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Meclizine dihydrochloride (NSC28728) 是一种组胺 H1 拮抗剂，用于治疗妊娠期间的晕动病、眩晕和恶心以及放射病。它是小鼠组成型雄甾烷受体激动剂，是人 CAR 的反向激动剂。它可透过血脑屏障，可用于多聚谷氨酰胺毒性障碍方面的研究。
T22070	DBIBB	LPA Receptor	GPCR/G Protein
	DBIBB 是一种特异性溶血磷脂酸 (LPA2) 的 2 型 G 蛋白偶联受体的非脂质激动剂，是一种能够治疗高强度γ 射线对造血和胃肠系统引起的急性放射综合征的潜在活性分子，是一种作未有机合成和药物研究中的中间体。 DBIBB 可用于制备各种化合物，可减轻胃肠道辐射综合征，增加肠隐窝存活率和肠细胞增殖，并减少细胞凋亡。
T2386	Pirfenidone S-7701,AMR-69,S-7701,AMR69,吡非尼酮	CCR; TGF-beta/Smad	Immunology/Inflammation; Microbiology/Virology; Stem Cells
	Pirfenidone (AMR69) 是一种抗纤维化剂，可减弱纤维细胞中CCL2和CCL12的产生。它可抑制细胞生长，并能降低人胶质瘤细胞系中的TGF-β2蛋白水平，具有抗炎活性。
T4434	Tirapazamine Tirazone,Win59075,SR4233,替拉扎明,SR259075	Others	Others
	Tirapazamine (Win59075) 是抗癌剂，对实体瘤中的缺氧细胞具有选择性细胞毒性，促使 DNA 中的单链和双链断裂，碱基损伤和细胞死亡。
T0357	Potassium iodide	Tyrosinase	Proteases/Proteasome
	Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。
T20681	Estramustine NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275	Microtubule Associated	Cytoskeletal Signaling
	Estramustine (LEO-275) 是一种与雌二醇相连的氮芥，通常为磷酸盐。它已被用于治疗前列腺肿瘤；还具有防辐射功能。它被前列腺细胞选择性吸收，并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。
T33701	NM-3 NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3	Apoptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	NM-3 是一种可口服的抗血管生成的抑制剂，具有抗肿瘤活性。NM-3在体外和体内可当作辐射调节剂使用。NM-3抑制血管内皮生长因子（VEGF），从而抑制内皮细胞的增殖。NM-3与活性氧的机制诱导细胞凋亡有关。
T34467	S 75 S75,S-75	Others	Others
	S 75 is a compound with radiation protective action.
T13862L	Recilisib sodium Brand name: Ex-RAD,ON 01210.Na,ON01210,ON-01210	Others	Others
	Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation protection studies. It appears tha
T4451L	Estramustine phosphate LS 299,NSC 89199,NSC-89199,LS-299,LS299	Others	Others
	Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.
T33292	Meradine NSC 22721,NSC-22721,NSC22721	Others	Others
	Meradine can be used for the treatment of radiation injury.
T3289L	Amifostine Hydrate	Others	Others
	Amifostine Hydrate is a radiation protective agent that induces splenic vasodilation and blocks autonomic ganglion.
T31825	Fluoromisonidazole
	Fluoromisonidazole, a Radiation-Sensitizing Agent, can be used for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapy.
T3289L2	Amifostine sodium WR-2721 sodium,WR2721 sodium,WR 2721 sodium	Others	Others
	Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
T34357	Ro 31-0313 Ro 310313,Ro-31-0313	Others	Others
	Ro 31-0313 is a metabolite of Ro 03-8799, radiation sensitizing agent.
TP2405	Romurtide MDP-lys(L18),CCRIS 1220,DJ-7041,Nopia
	Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.
T11118	Duocarmycin SA	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Duocarmycin SA is an extremely potent cytotoxic agent and antitumor antibiotic that induces sequence-selective alkylation of duplex DNA, with an IC50 of 10 pM. It demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells when combined with proton radiation in vitro.
T82768	CBLB 612
	CBLB 612是一种具有双重功效的化合物，既能作为抗辐射辅助剂，也能用作抗肿瘤剂。
T38267	Valeryl-L-carnitine (chloride) Valeryl-L-carnitine (chloride),L-Valerylcarnitine	Others	Others
	Valeryl-L-carnitine is a short-chain acylcarnitine and a derivative of L-carnitine . Valeryl-L-carnitine levels increase in the serum of rhesus monkeys following exposure to 7 and 10 Gray units (Gy) of ionizing radiation.[1]
T33407	MitoEbselen-2 chloride MitoPeroxidase-2,MitoPeroxidase 2,MitoEbselen 2,MitoEbselen-2	Others	Others
	MitoEbselen-2 is a radiation mitigator which reduces lipid hydroperoxides and prevents apoptotic cell death. When administered 24 hours postirradiation, MitoEbselen-2 was shown to increase the survival of mice exposed to whole body γ-irradiation.
T85138	2-Stearoyl-rac-glycerol 18:0-MG,2-Monostearin,MG(0:0/18:0/0:0)	Others	Others
	2-Stearoyl-rac-glycerol, a monoacylglycerol with stearic acid at the sn-2 position, exhibits elevated levels in mouse plasma after low-dose ionizing radiation exposure and in rat kidney following ischemia-reperfusion injury models.
T72969	Actinoquinol 阿克汀喹	Others	Others
	Actinoquinol 是一种 UVB 吸收剂，有助于人眼抵御光氧化和其他氧化。
T84725	Melanin	Others	Others
	Melanin是能够应对环境压力如紫外线(UV)、氧化剂和电离辐射的多功能生物色素。
T36704	CCT241533 dihydrochloride CCT 241533 dihydrochloride	Others	Others
	Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes. Caldwell et al (2011) Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. J.Med.Chem. 54 580 PMID:21186793
T33487	Motexafin gadolinium PCI0120,Gd texaphyrin,PCI-0120,PCI 0120,Gd-Texgadolinium,API-GP 3	Others	Others
	Motexafin gadolinium, also known as PCI 0120, is a synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating rea
T35821	CAY10721	Others	Others
	CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy.
T84943	5-Androstenetriol Δ5-AT	Others	Others
	5-Androstenetriol, a steroid and active metabolite of dehydroepiandrosterone (DHEA), demonstrates significant therapeutic effects. Administered at 0.75 mg/25 g body weight, it mitigates radiation-induced mortality and facilitates hematopoietic recovery from surviving stem cells in mice. Moreover, a dosage of 40 mg/kg enhances survival rates in rats subjected to surgical trauma-induced sepsis. Additionally, elevated urinary levels of 5-androstenetriol are observed in women suffering from androgen...
T41037	Ecamsule disodium	Others	Others
	Ecamsule disodium is a versatile UVA filter compound commonly employed in the formulation of sunscreen products. Its primary role is to mitigate the potential harm posed by solar radiation through the prevention of various biological repercussions induced by UV exposure. These include the inhibition of pyrimidine dimer formation, the reduction of p53 protein accumulation, and the downregulation of collagenase 2 expression.
T68708	Denibulin HCl	Others	Others
	Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells. The results of preclinical study demonstrated that MN-029 could cause rapid vascular shutdown in solid tumors, dose-dependent secondary tumor cell killing, and effective enhancement of the antitumor effects of radiation and cisplatin chemotherapy.
T69714	Etanidazole	Others	Others
	Etanidazole (SR-2508) is a 2-nitroimidazole drug with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
T11449	Golotimod hydrochloride (229305-39-9 free base) Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride	STAT	JAK/STAT signaling; Stem Cells
	Golotimod (SCV 07) hydrochloride 是一种免疫调节肽，具抗菌活性，能显著提升抗结核疾病研究效果。该化合物通过刺激胸腺和脾细胞增殖、改善巨噬细胞功能，展现其生物调节能力。此外，Golotimod hydrochloride 通过抑制STAT3信号传导，有效调节接受放疗或与顺铂联用治疗动物模型中的口腔粘膜炎持续时间和严重程度。还显示出对研究复发性生殖器单纯疱疹病毒 2 型 (HSV-2) 具有潜在应用价值。
T71908	NU1085	Others	Others
	NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer). Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h.
T72009	N-Phenylthiourea	Others	Others
	N-Phenylthiourea is a tyrosinase inhibitor and building block. It increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity when used at a concentration of 0.01 μM. N-Phenylthiourea has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities. It has also been used as a genetic marker for taste because only some people detect it as a bitter taste.

化合物

Cat.No: T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

Cat.No: T2046

Synonym: Nimorazol,Nitrimidazine,尼莫唑,K-1900,Naxogin,尼莫拉唑

Target: Others, Antibiotic, Parasite

Ondansetron hydrochloride dihydrate

Cat.No: T1478

Synonym: 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride

Target: 5-HT Receptor

Cat.No: T19957

Synonym: XU 292A,XU-292A,XU292A

Target: Others

Cat.No: T2068

Target: Phosphatase

Cystamine dihydrochloride

Cat.No: T20109

Target: Others

Cat.No: T0698

Synonym: UV-24,二羟苯宗,Benzophenone-8,2,2'-Dihydroxy-4-methoxybenzophenone,Dioxybenzon,Cyasorb UV 24,Advastab 47

Target: Others

Cat.No: T15943

Target: p38 MAPK, Chk

Cat.No: T12019

Target: Others

Ondansetron hydrochloride

Cat.No: T6616

Synonym: SN 307,盐酸昂丹司琼,帕罗西汀杂质A,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran

Target: 5-HT Receptor

Cat.No: T2020

Target: Others

Rusalatide acetate (497221-38-2 free base)

Cat.No: TP1024

Synonym: Rusalatide acetate,TP508 amide acetate

Target: Others

Cat.No: T31929

Synonym: PLA 695,PLA-695,PLA695

Target: Phospholipase

4-Methylbenzylidene camphor

Cat.No: T7465

Synonym: Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC

Target: AChE

Cat.No: T24184

Synonym: DAU6215CL,UNII-00S0D0OEKR,U-98079A,U 98079A,DAU 6215CL

Target: 5-HT Receptor

Cat.No: T6970

Synonym: RK-33,RK 33

Target: COX

Cat.No: T38681

Target: Others

Meclizine dihydrochloride

Cat.No: T1110

Synonym: Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪

Target: Apoptosis, Histamine Receptor

Cat.No: T22070

Target: LPA Receptor

Cat.No: T2386

Synonym: S-7701,AMR-69,S-7701,AMR69,吡非尼酮

Target: CCR, TGF-beta/Smad

Cat.No: T4434

Synonym: Tirazone,Win59075,SR4233,替拉扎明,SR259075

Target: Others

Potassium iodide

Cat.No: T0357

Target: Tyrosinase

Cat.No: T20681

Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275

Target: Microtubule Associated

Cat.No: T33701

Synonym: NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3

Target: Apoptosis, Reactive Oxygen Species

Cat.No: T34467

Synonym: S75,S-75

Target: Others

Recilisib sodium

Cat.No: T13862L

Synonym: Brand name: Ex-RAD,ON 01210.Na,ON01210,ON-01210

Target: Others

Estramustine phosphate

Cat.No: T4451L

Synonym: LS 299,NSC 89199,NSC-89199,LS-299,LS299

Target: Others

Cat.No: T33292

Synonym: NSC 22721,NSC-22721,NSC22721

Target: Others

Amifostine Hydrate

Cat.No: T3289L

Target: Others

Fluoromisonidazole

Cat.No: T31825

Amifostine sodium

Cat.No: T3289L2

Synonym: WR-2721 sodium,WR2721 sodium,WR 2721 sodium

Target: Others

Cat.No: T34357

Synonym: Ro 310313,Ro-31-0313

Target: Others

Cat.No: TP2405

Synonym: MDP-lys(L18),CCRIS 1220,DJ-7041,Nopia

Cat.No: T11118

Target: Others, ADC Cytotoxin

Cat.No: T82768

Valeryl-L-carnitine (chloride)

Cat.No: T38267

Synonym: Valeryl-L-carnitine (chloride),L-Valerylcarnitine

Target: Others

MitoEbselen-2 chloride

Cat.No: T33407

Synonym: MitoPeroxidase-2,MitoPeroxidase 2,MitoEbselen 2,MitoEbselen-2

Target: Others

2-Stearoyl-rac-glycerol

Cat.No: T85138

Synonym: 18:0-MG,2-Monostearin,MG(0:0/18:0/0:0)

Target: Others

Cat.No: T72969

Synonym: 阿克汀喹

Target: Others

Cat.No: T84725

Target: Others

CCT241533 dihydrochloride

Cat.No: T36704

Synonym: CCT 241533 dihydrochloride

Target: Others

Motexafin gadolinium

Cat.No: T33487

Synonym: PCI0120,Gd texaphyrin,PCI-0120,PCI 0120,Gd-Texgadolinium,API-GP 3

Target: Others

Cat.No: T35821

Target: Others

5-Androstenetriol

Cat.No: T84943

Synonym: Δ5-AT

Target: Others

Ecamsule disodium

Cat.No: T41037

Target: Others

Cat.No: T68708

Target: Others

Cat.No: T69714

Target: Others

Golotimod hydrochloride (229305-39-9 free base)

Cat.No: T11449

Synonym: Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride

Target: STAT

Cat.No: T71908

Target: Others

N-Phenylthiourea

Cat.No: T72009

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3399	Psoralidin	Others; Estrogen/progestogen Receptor; Reactive Oxygen Species; Lipoxygenase; Gamma-secretase; Akt; COX; Antibacterial	Cytoskeletal Signaling; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Psoralidin 是COX-2和5-LOX 的抑制剂，有抗癌，抗菌和抗炎作用。它显著下调NOTCH1信号传导，还极大地诱导活化氧产生。
TN1921	Meloside A 异牡荆素-2''-O-葡萄糖苷,Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside	Others	Others
	Meloside A (Isovitexin 2''-O-β-D-glucoside) 是一种从大麦中提取的苯丙烷类天然产物。 Meloside A 对过量的 UV-B 辐射具有抗氧化和保护作用，并与对病原体的抵抗力有关。
T2804	Panaxatriol 人参三醇,Panaxtriol	Others	Others
	Panaxatriol (Panaxtriol) 是一种能够减轻由于辐射损伤造成的骨髓抑制的天然产物。
TMO2685	10-Hydroxydecanoic Acid NSC 15139,10-羟基癸烯酸,10-羟基癸酸	Antibacterial	Microbiology/Virology
	10-Hydroxydecanoic Acid (NSC 15139) 是一种存在于蜂王浆中的 10-hydroxy-trans-2-decenoic acid 的饱和脂肪酸，具有抗炎活性。
T1556	Ornidazole Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ornidazole (Tiberal) 是一种5-硝基咪唑衍生物，能抗原生动物和厌氧菌。
T3O2784	Vitamin B6 维生素B6	Others	Others
	Vitamin B6 是人体某些辅酶的成分，参与多种代谢反应，特别是与氨基酸代谢有关。维生素B6在防治妊娠和放射病呕吐中的临床应用。
T4759	Urocanic acid 4-Imidazoleacrylic acid,尿刊酸	Others; Endogenous Metabolite	Metabolism; Others
	Urocanic acid（4-Imidazoleacrylic acid）存在于表皮中，是哺乳动物皮肤中紫外线（UV）辐射的主要吸收物。
T15705	Laminaran β-1,3-Glucan
	Laminaran 是一种从褐藻中分离出来的 β-1-3-葡聚糖，常作为 Dectin-1 的典型配体，具有抗癌、免疫调节和辐射防护作用。 Laminaran 可被葡糖酶催化。Laminaran 在体内外实验中显示出抗肿瘤活性，可用于预防和治疗癌症。
T2A2532	L-Histidine Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine	Mitochondrial Metabolism; Endogenous Metabolite	Metabolism
	L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T5S0045	Isofraxidin 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶	MMP; ERK; p38 MAPK; TLR; COX	Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
	Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分，抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞，抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达，还抑制TLR4/髓样分化蛋白 2 复合物的形成。
T2O2733	L-Cystine Cystine Acid,cystine,胱氨酸,L-胱氨酸	Antioxidant; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用，保护组织免受辐射和污染，减缓衰老过程。它还有助于蛋白质合成。
TN1821	Kaempferol 3-O-arabinoside 山奈酚-3-O-α-L-吡喃阿拉伯糖苷,堪非醇 3-O-阿拉伯糖苷	ROS; Antifection	Immunology/Inflammation; Microbiology/Virology
	Kaempferol-3-O-α±-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging ROS, and protect cellular membrane against ROS; they can be applicable to new cosmeceuticals for antioxidant, antiaging, and antibacterial activity.
T82046	Irisquinone
	Irisquinone，一种具有抗癌活性的天然产物，同时作为癌症放射增敏剂。该化合物通过降低GSH水平并抑制DNA单链断裂修复，展现其药理作用。

天然产物

Cat.No: T3399

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Cat.No: TN1921

Synonym: 异牡荆素-2''-O-葡萄糖苷,Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside

Target: Others

Cat.No: T2804

Synonym: 人参三醇,Panaxtriol

Target: Others

10-Hydroxydecanoic Acid

Cat.No: TMO2685

Synonym: NSC 15139,10-羟基癸烯酸,10-羟基癸酸

Target: Antibacterial

Cat.No: T1556

Synonym: Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T3O2784

Synonym: 维生素B6

Target: Others

Cat.No: T4759

Synonym: 4-Imidazoleacrylic acid,尿刊酸

Target: Others, Endogenous Metabolite

Cat.No: T15705

Synonym: β-1,3-Glucan

Cat.No: T2A2532

Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Target: Mitochondrial Metabolism, Endogenous Metabolite

Cat.No: T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

Target: MMP, ERK, p38 MAPK, TLR, COX

Cat.No: T2O2733

Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸

Target: Antioxidant, Ferroptosis, Endogenous Metabolite

Kaempferol 3-O-arabinoside

Cat.No: TN1821

Synonym: 山奈酚-3-O-α-L-吡喃阿拉伯糖苷,堪非醇 3-O-阿拉伯糖苷

Target: ROS, Antifection

Cat.No: T82046

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03614	DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO) DNA photolyase,Deoxyribodipyrimidine photo-lyase,phr,phrA,Ph...	Synechococcus	E. coli
	Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 74.3 kDa and the accession number is P05...
TMPH-03452	NDPK Protein, S. cerevisiae, Recombinant (His) Nucleoside diphosphate kinase,YNK1	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P36010.
TMPH-03451	NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) YNK1,Nucleoside diphosphate kinase	Saccharomyces cerevisiae	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P36010.
TMPJ-00826	TXN Protein, Human, Recombinant (His) ADF,TXN,TRX1,Thioredoxin,TRX,ATL-Derived Factor,TRDX,Surface...	Human	E. coli
	Thioredoxin (TXN) is a member of the Thioredoxin family. Thioredoxin exists as a disulfide-linked homodimer and contains one Thioredoxin domain. Thioredoxin is up-regulated by ionizing radiation. Thioredoxin participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin also plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contri...
TMPY-00261	Meprin beta Protein, Human, Recombinant (His) meprin A, β,Meprin β,meprin A, beta	Human	HEK293 Cells
	MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in the kidney and intestine. Meprins are cell membrane, oligomeric metalloendopeptidases composed of two distinct but evolutionarily related subunits, alpha, and beta. MEP1A is mapped to the short arm of chromosome 6 by the use of radiation and som...
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His) ALDHIII,aldehyde dehydrogenase 3 family, member A1,ALDH3	Human	Baculovirus Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi...
TMPH-01267	RNF13 Protein, Human, Recombinant (His & Myc) RING finger protein 8,RNF8,E3 ubiquitin-protein ligase RNF8,...	Human	E. coli
	E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of hist...

重组蛋白

DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03614

Species: Synechococcus

Expression System: E. coli

NDPK Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03452

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)

Cat.No: TMPH-03451

Species: Saccharomyces cerevisiae

Expression System: E. coli

TXN Protein, Human, Recombinant (His)

Cat.No: TMPJ-00826

Species: Human

Expression System: E. coli

Meprin beta Protein, Human, Recombinant (His)

Cat.No: TMPY-00261

Species: Human

Expression System: HEK293 Cells

ALDH3A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02299

Species: Human

Expression System: Baculovirus Insect Cells

RNF13 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01267

Species: Human

Expression System: E. coli

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