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Search Results for " nucleic acid "

118

抑制剂 & 化合物

9

天然产物

3

化合物库

3

TargetMol 试剂盒

8

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；
L3510	甲基化化合物库		128 compounds
	128 种甲基化相关的化合物，可以用于高通量和高内涵筛选；
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；

化合物库

核苷类化合物库

Cat.No: L1720

Compounds: 334

甲基化化合物库

Cat.No: L3510

Compounds: 128

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0104B	Protein A/G Immunomagnetic Beads Protein A/G 免疫沉淀磁珠	Suspension in bottle	IP, Co-IP, ChIP
C0104	Protein A/G Immunoprecipitation Kit Protein A/G 免疫沉淀试剂盒	Suspension in bottle	IP, Co-IP, ChIP
C0105	Protein A Immunoprecipitation Kit Protein A 免疫沉淀试剂盒	Suspension in bottle	IP, Co-IP, ChIP

TargetMol 试剂盒

Protein A/G 免疫沉淀磁珠

Cat.No: C0104B

Protein A/G 免疫沉淀试剂盒

Cat.No: C0104

Protein A 免疫沉淀试剂盒

Cat.No: C0105

Cat. No.	Product Name	Target	Signaling Pathways
T83668	Nucleic Acid Dye Green I NucGel Green I Nucleic Acid Gel Stain,Green I Nucleic Acid Gel Stain
	Nucleic Acid Dye Green I是一种不可渗透细胞的荧光染料，通常用于双链DNA和单链DNA的定量分析。它的激发和发射峰值分别为497 nm和520 nm。Nucleic Acid Dye Green I也被用于基因表达和RT-PCR检测。
T19156	Locked nucleic acid 1	Others	Others
	Locked nucleic acid 1 is an LNA-type nucleoside derivative.
T19065	Thiazole Orange	Others	Others
	Thiazole Orange 是不对称的花青素染料，能够与寡核苷酸偶联，制备荧光杂交探针。它可用于分析网织红细胞。
TD0002L	CelRed nucleic acid gel stain 10,000× concentrate in DMSO
	1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells. Ames test results also show that the mutagenicity of CelRed dye is much less than that of EB. 2) High sensitivi
TD0003	CelGreen nucleic acid gel stain (10,000×, water)	Others	Others
	CelGreen 是一种具有独特参与性的荧光染料，可与所有 dsDNA 双螺旋沟区域结合。在游离状态下，侧链和 CelGreen 发出微弱的荧光，但一旦与双链DNA 结合，荧光就会大大增强。因此，CelGreen 的荧光信号强度与双链DNA 的量有关，可以根据荧光信号检测PCR 系统中双链DNA 的量。
TD0003L	CelGreen nucleic acid gel stain 10,000× concentrate in DMSO
	CelGreen nucleic acid gel stain 10,000× concentrate in DMSO is a fluorescent dye with a unique involvement that binds to all dsDNA double helix sulcus regions.In the free state, the side strand and CelGreen emit weak fluorescence, but the fluorescence is greatly enhanced once they are combined with the double-stranded DNA. Therefore, the fluorescence signal strength of CelGreen is related to the amount of double-stranded DNA, and the amount of double-stranded DNA in the PCR system can be detec...
TD0004	Celfinder nucleic acid gel stain 10,000× concentrate in DMSO
	Celfinder is a new kind of nucleic acid dye, which has the advantages of safety and sensitivity, and can be used as a dye for various kinds of nucleic acid electrophoresis.Unlike EB, which is highly carcinogenic, Celfinder is a flower-like dye with low to
TD0002	CelRed nucleic acid gel stain 10,000× concentrate in water
	1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells, and Ames test results also show that the mutagenicity of CelRed dye is much less than EB. 2) High sensitivity:
T9098	DMG-PEG 2000 DMG-PEG2000	Others	Others
	DMG-PEG 2000 (DMG-PEG2000) 可用于脂质纳米颗粒制备，用于口服质粒 DNA 的体内传递途径，提高纳米颗粒的黏液渗透性和传递效率。它也可用于 siRNA 转染的脂质体的制备，能够提高转染效率。
T15507	Hycanthone Etrenol(mesylate),Win 249-33,海恩酮	DNA/RNA Synthesis; Topoisomerase; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Hycanthone (Etrenol(mesylate)) 是 Lucanthone 的生物活性代谢产物，是一种抗血吸虫病药。它是一个噻吨酮类 DNA 嵌入剂，可抑制 RNA 合成以及 DNA 拓扑异构酶 I 和 II。它通过直接蛋白质结合来抑制核酸生物合成并抑制嘌呤内切核酸酶1，KD 为 10 nM。
T11086	DOTAP chloride (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride	Others	Others
	DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) 是高效的阳离子脂质，可以在不使用辅助脂质的情况下，作用于瞬时或者稳定转染 DNA (质粒、bacmids) 和修饰核酸 (反义寡核苷酸)。
TD0082	EDANS sodium EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-氨乙基氨)-1-萘磺酸钠盐,5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt	Others	Others
	EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) 是开发基于 FRET 的核酸探针的供体，该探针广泛用于实时 PCR 测定。
TD0001	SYBR GREEN 1 SUPER Green I （效果同SYBR Green I）核酸染料（10,000× DMSO溶液）（电泳级）,SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料	Others	Others
	SYBR GREEN 1 是一种不对称花青染料，用于检测核酸。它由一个 N-烷基化的苯并噻唑或苯并恶唑环系统组成，通过一甲基桥连接到吡啶鎓或喹啉鎓环系统。 SYBR Green I 与 dsDNA 的小沟结合，在 480 nm 波长处被激发。它具有 520 nm 的峰值荧光发射。
T83656	DLIN-MC4-DMA	Others	Others
	DLIN-MC4-DMA 是一种脂质膜，是一种潜在的核酸载体。
T74233	Dlin-MeOH	Others	Others
	Dlin-MeOH 是一种脂质膜，是一种潜在的核酸载体，可用于合成 DLin-MC3-DMA。
T15140	DLinDMA	Others	Others
	DLinDMA 是一种稳定的核酸脂质颗粒 (SNALPs) 中的关键脂质成分，是一种可电离的阳离子脂质。它可用于siRNA 递送的研究。
T36710	N-(2-hydroxyethyl)-Naphthalimide
	N-(2-hydroxyethyl)-Naphthalimide是一种用于核酸检测的荧光探针，其荧光可被猝灭。
T18945	CY3 Sulfo-Cyanine3,磺基-CY3 羧酸	Others	Others
	CY3 (Sulfo-Cyanine3) 是传统的蛋白质和核酸的橙色荧光标记物(λex=554, λem=568)。
T8354	Triazavirin	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Triazavirin 是一种核酸的核苷类似物和抗病毒剂，通过抑制病毒 RNA 和 DNA 的合成以及基因组片段的复制而起作用。在流感传播阶段，它可作为保护剂。
T4068	E6446 dihydrochloride	TLR	Immunology/Inflammation
	E6446 dihydrochloride 是一种新型合成拮抗剂，用于核酸感应 TLR；有效抑制对 HEK:TLR9 细胞的 DNA 刺激，IC50 为 10 nM。
T83655	DLIN-MC2-DMA DLin-M-C2-DMA	Others	Others
	DLIN-MC2-DMA (DLin-M-C2-DMA) 是一种脂质膜，是一种潜在的核酸载体。
T28475	Pyrazoloacridine PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	Pyrazoloacridine (PD 115934) 是一种核酸结合剂，在 K562 细胞中抑制 topo I 和 II 的活性，IC50 为 1.25 μM。 Pyrazoloacridine 具有抗癌活性。
T38709	PFM39	Others	Others
	PFM39 是一种选择性 MRE11 核酸外切酶抑制剂，是 Mirin 类似物，可延长有丝分裂。PFM39 抑制 HR，可缓解由 EXO1/BLM 耗竭引起的修复缺陷。
T84299	BHQ3 Maleimide
	BHQ3 Maleimide 属于荧光探针，可以消除背景荧光，可用于蛋白质标记、核酸标记和细胞成像。
T41324	L319 Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate	Others	Others
	L319 (Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) 是一种脂质膜，是一种潜在的核酸载体。
T10509	Xanthine oxidase-IN-1 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid	Xanthine Oxidase	Metabolism
	Xanthine oxidase-IN-1是一种有效的黄嘌呤氧化酶抑制剂(IC50值:6.5 nM),是一种利用核酸和核苷酸介质降解产生的生物活性核苷酸在嘌呤分解代谢中起核心作用的化合物，
T8333	Aurintricarboxylic acid ATA,NSC-4056,NSC4056,金精三羧酸,NSC 4056	Apoptosis; P2X Receptor; Influenza Virus; Topoisomerase	Apoptosis; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Aurintricarboxylic acid (NSC-4056) 是高效的αβ-亚甲基-ATP 敏感选择性P2X1Rs 和P2X3Rs 变构拮抗剂。它是核糖核酸酶和拓扑异构酶 II 的有效抑制剂，可阻止核酸与酶结合。
T2130	Propidium Iodide PI,碘化丙啶,碘化丙啶（PI）	Others	Others
	Propidium Iodide (PI) 是一种可用于细胞染色的红色荧光染料，适用于荧光显微镜、共聚焦显微镜、流式细胞仪以及荧光计分析。在水溶液中，Propidium Iodide 的 Ex/Em 为 493/636 nm；与核酸结合后，PI-核酸的 Ex/Em 变为 535/617 nm，同时荧光信号增强 20-30 倍。
T37636	2'-Deoxyguanosine 5'-monophosphate disodium 5′-dGMP disodium	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) 是一种核酸三磷酸鸟苷（GTP）衍生物，可作为可氧化靶标，可用于和其他化合物组成多元配合物。
T1038	Fludarabine NSC 118218,Fludarabinum,氟达拉宾,氟达拉滨,F-ara-A	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; STAT	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; JAK/STAT signaling; Stem Cells
	Fludarabine (Fludarabinum) 是一种氟化嘌呤类似物，一种核酸合成抑制剂和 STAT1 激活抑制剂。Fludarabine 具有抗肿瘤活性，可以用于治疗白血病和淋巴瘤。
T2201	6-Mercaptopurine hydrate 6-Mercaptopurine monohydrate,6-巯基嘌呤(一水合物),6-Mercaptopurine (6-MP) Monohydrate,6-巯基嘌呤一水合物	Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	6-Mercaptopurine hydrate (6-Mercaptopurine monohydrate) 是一种核苷代谢抑制剂。它通过抑制嘌呤代谢来干扰核酸合成，通常与其他药物联合用于白血病的治疗或缓解维持计划。
T0010	6-Mercaptopurine 6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤	Nucleoside Antimetabolite/Analog; Others; Dehydrogenase; Endogenous Metabolite; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	6-Mercaptopurine (6-MP) 是一种具有免疫抑制特性的抗代谢物抗肿瘤剂。它通过抑制嘌呤代谢来干扰核酸合成，通常与其他药物联合用于白血病的治疗或缓解维持计划。
TP2505L	LAH4 acetate KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base)	Antibacterial	Microbiology/Virology
	LAH4 acetate 是所设计的两性肽抗生素的α -螺旋结构，能够与DNA 络合，与细胞表面膜结合后被包裹在核内体中，随着pH 值的下降破坏核内体膜。具有强大的抗菌、核酸转染和细胞渗透活性。LAH4 acetate 具有较高的质粒DNA 传递能力。LAH4 acetate 对细菌膜外膜中的阴离子脂具有很强的亲和力。
T70961	Dmb-rifampicin	Others	Others
	Dmb-rifampicin is an inhibitor of nucleic acid polymerases.
T19022	LDS-751	Others	Others
	LDS-751 is a stain of nucleic acid.
T36299	Uridine triphosphate 13C9,15N2 sodium Uridine triphosphate 13C9,15N2 sodium	Others	Others
	Uridine triphosphate 13C9,15N2 (UTP 13C9,15N2) sodium, a labeled form of uridine triphosphate sodium, facilitates nucleic acid synthesis.
T36972	5-O-TBDMS-N4-Benzoyl-2-deoxycytidine 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine	Others	Others
	5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.
T38676	5'-O-DMT-2'-O-TBDMS-rI	Others	Others
	5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside utilized in the synthetic process of deoxyribonucleic acid (DNA) or nucleic acid.
TNU0029	N4-Methylcytidine	Others	Others
	Other modified nucleoside; building block for nucleic acid
T31696	EthD-1 EthD1,Ethidium Homodimer-1
	EthD-1 is a cell-impermeant viability indicator. It acts as a high-affinity nucleic acid stain.
T18897	5(6)-ROX 5(6)-Carboxy-X-rhodamine	Others	Others
	5(6)-ROX, a nucleic acid fluorescent label, serves as a reference dye in real-time polymerase chain reaction (PCR) applications.
TNU0686	2’,3’-O-Isopropylidene-5-hydroxymethyl uridine	Others	Others
	5-modified pyrimidine nucleoside, building block for nucleic acid
T74379	DLin-K-C3-DMA	Others	Others
	DLin-K-C3-DMA 是一种阳离子脂质，可用于核酸脂质颗粒的合成，以输送核酸。
TNU0002	3’-Deoxy-3’-alpha-C-methylcytidine	Others	Others
	3'-Deoxy-3'-alpha-C-methylcytidine is a Nucleoside; Used for nucleoside and nucleic acid modifications.
TNU0610	Methyl 3,5-di-O-benzyl-D-ribofuranoside	Others	Others
	Methyl 3,5-di-O-benzyl-D-ribofuranoside is a Carbohydrate; Used for nucleoside and nucleic acid modifications.
T24149	HQCG	Others	Others
	HQCG is an inhibitor of 2- Oxoglutarate- dependent nucleic acid demethylase that also acts as a prolyl- 4- hydroxylase inhibitor.
T39201	7-TFA-ap-7-Deaza-dA	Others	Others
	7-TFA-ap-7-Deaza-dA, a modified nucleoside, finds application in the synthesis of deoxyribonucleic acid or nucleic acid.
T40500	5'-O-DMT-N2-DMF-dG 5'-O-DMT-N2-DMF-dG	Others	Others
	5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.
T28320	PD 121373 PD121373,PD-121373	Others	Others
	PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations.
T40772	7-TFA-ap-7-Deaza-dG	Others	Others
	5'-O-TBDMS-dG, a modified nucleoside, is utilized in the synthesis of deoxyribonucleic acid or nucleic acid.

化合物

Nucleic Acid Dye Green I

Cat.No: T83668

Synonym: NucGel Green I Nucleic Acid Gel Stain,Green I Nucleic Acid Gel Stain

Locked nucleic acid 1

Cat.No: T19156

Target: Others

Thiazole Orange

Cat.No: T19065

Target: Others

CelRed nucleic acid gel stain *10,000× concentrate in DMSO*

Cat.No: TD0002L

CelGreen nucleic acid gel stain (10,000×, water)

Cat.No: TD0003

Target: Others

CelGreen nucleic acid gel stain *10,000× concentrate in DMSO*

Cat.No: TD0003L

Celfinder nucleic acid gel stain *10,000× concentrate in DMSO*

Cat.No: TD0004

CelRed nucleic acid gel stain *10,000× concentrate in water*

Cat.No: TD0002

Cat.No: T9098

Synonym: DMG-PEG2000

Target: Others

Cat.No: T15507

Synonym: Etrenol(mesylate),Win 249-33,海恩酮

Target: DNA/RNA Synthesis, Topoisomerase, Parasite

Cat.No: T11086

Synonym: (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride

Target: Others

Cat.No: TD0082

Synonym: EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-氨乙基氨)-1-萘磺酸钠盐,5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt

Target: Others

Cat.No: TD0001

Synonym: SUPER Green I （效果同SYBR Green I）核酸染料（10,000× DMSO溶液）（电泳级）,SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料

Target: Others

Cat.No: T83656

Target: Others

Cat.No: T74233

Target: Others

Cat.No: T15140

Target: Others

N-(2-hydroxyethyl)-Naphthalimide

Cat.No: T36710

Cat.No: T18945

Synonym: Sulfo-Cyanine3,磺基-CY3 羧酸

Target: Others

Cat.No: T8354

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis

E6446 dihydrochloride

Cat.No: T4068

Target: TLR

Cat.No: T83655

Synonym: DLin-M-C2-DMA

Target: Others

Pyrazoloacridine

Cat.No: T28475

Synonym: PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934

Target: Apoptosis, Topoisomerase

Cat.No: T38709

Target: Others

Cat.No: T84299

Cat.No: T41324

Synonym: Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate

Target: Others

Xanthine oxidase-IN-1

Cat.No: T10509

Synonym: 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid

Target: Xanthine Oxidase

Aurintricarboxylic acid

Cat.No: T8333

Synonym: ATA,NSC-4056,NSC4056,金精三羧酸,NSC 4056

Target: Apoptosis, P2X Receptor, Influenza Virus, Topoisomerase

Propidium Iodide

Cat.No: T2130

Synonym: PI,碘化丙啶,碘化丙啶（PI）

Target: Others

2'-Deoxyguanosine 5'-monophosphate disodium

Cat.No: T37636

Synonym: 5′-dGMP disodium

Target: Endogenous Metabolite

Cat.No: T1038

Synonym: NSC 118218,Fludarabinum,氟达拉宾,氟达拉滨,F-ara-A

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, STAT

6-Mercaptopurine hydrate

Cat.No: T2201

Synonym: 6-Mercaptopurine monohydrate,6-巯基嘌呤(一水合物),6-Mercaptopurine (6-MP) Monohydrate,6-巯基嘌呤一水合物

Target: Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis

6-Mercaptopurine

Cat.No: T0010

Synonym: 6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤

Target: Nucleoside Antimetabolite/Analog, Others, Dehydrogenase, Endogenous Metabolite, Autophagy

Cat.No: TP2505L

Synonym: KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base)

Target: Antibacterial

Cat.No: T70961

Target: Others

Cat.No: T19022

Target: Others

Uridine triphosphate 13C9,15N2 sodium

Cat.No: T36299

Synonym: Uridine triphosphate 13C9,15N2 sodium

Target: Others

5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

Cat.No: T36972

Synonym: 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

Target: Others

5'-O-DMT-2'-O-TBDMS-rI

Cat.No: T38676

Target: Others

N4-Methylcytidine

Cat.No: TNU0029

Target: Others

Cat.No: T31696

Synonym: EthD1,Ethidium Homodimer-1

Cat.No: T18897

Synonym: 5(6)-Carboxy-X-rhodamine

Target: Others

2’,3’-O-Isopropylidene-5-hydroxymethyl uridine

Cat.No: TNU0686

Target: Others

Cat.No: T74379

Target: Others

3’-Deoxy-3’-alpha-C-methylcytidine

Cat.No: TNU0002

Target: Others

Methyl 3,5-di-O-benzyl-D-ribofuranoside

Cat.No: TNU0610

Target: Others

Cat.No: T24149

Target: Others

7-TFA-ap-7-Deaza-dA

Cat.No: T39201

Target: Others

5'-O-DMT-N2-DMF-dG

Cat.No: T40500

Synonym: 5'-O-DMT-N2-DMF-dG

Target: Others

Cat.No: T28320

Synonym: PD121373,PD-121373

Target: Others

7-TFA-ap-7-Deaza-dG

Cat.No: T40772

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4706	Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐	DNA/RNA Synthesis; Endogenous Metabolite; P2Y Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) 是一种选择性 P2Y6受体激动剂，EC50为300 nM，对人 P2Y6受体的 pEC50为6.52。它可刺激炎症介质的产生、吞噬作用和血管收缩，催化多种底物的葡糖醛酸糖化反应，用于核酸生物合成。
T40370	2′-Deoxyadenosine 5′-monophosphate disodium	Endogenous Metabolite	Metabolism
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T4746	Purine 7H-Imidazo(4,5-d)pyrimidine,嘌呤	Others; Endogenous Metabolite	Metabolism; Others
	Purine (7H-Imidazo(4,5-d)pyrimidine) 是内源性代谢产物的一种。
T5079	Adenosine 5'-diphosphate sodium salt 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸，是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T1362	Hypoxanthine 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin	Others; Endogenous Metabolite	Metabolism; Others
	Hypoxanthine (Purin-6-ol)，也被称为 purine-6-ol 或 Hyp，是一种天然存在的嘌呤衍生物，是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下，Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤，黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。
T4737	2'-Deoxyadenosine-5'-monophosphate D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸，是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
T38141	Glycerophospholipids, cephalins Phosphatidylethanolamines (egg)
	Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物，在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用，可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
TN7272	4-chloro-α-Cyanocinnamic Acid Cl-CCA	Others	Others
	4-Chloro-α-cyanocinnamic acid (Cl-CCA), a phenylpropanoid derivative of cinnamic acid synthesized from phenylalanine by plants, exhibits a propensity for co-crystallization with a range of biomolecules, including peptides and nucleic acids.
T11233	Erythromycin thiocyanate	Antibacterial	Microbiology/Virology
	Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .Erythromycin thiocyanate

天然产物

Uridine-5'-diphosphate disodium salt

Cat.No: T4706

Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐

Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor

2′-Deoxyadenosine 5′-monophosphate disodium

Cat.No: T40370

Target: Endogenous Metabolite

Cat.No: T4746

Synonym: 7H-Imidazo(4,5-d)pyrimidine,嘌呤

Target: Others, Endogenous Metabolite

Adenosine 5'-diphosphate sodium salt

Cat.No: T5079

Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Cat.No: T1362

Synonym: 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin

Target: Others, Endogenous Metabolite

2'-Deoxyadenosine-5'-monophosphate

Cat.No: T4737

Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Target: Others, Endogenous Metabolite

Glycerophospholipids, cephalins

Cat.No: T38141

Synonym: Phosphatidylethanolamines (egg)

4-chloro-α-Cyanocinnamic Acid

Cat.No: TN7272

Synonym: Cl-CCA

Target: Others

Erythromycin thiocyanate

Cat.No: T11233

Target: Antibacterial

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00732	RtcB Protein, E. coli, Recombinant (His) rtcB,3'-phosphate/5'-hydroxy nucleic acid ...	E. coli	P. pastoris (Yeast)
	GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.
TMPJ-01450	SARS-CoV-2 Helicase Protein (His & MBP) SARS-CoV 2 nsp13,SARS-CoV 2 Helicase	SARS-CoV-2	E. coli
	The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 demonstrated that it can unwind both doublestranded DNA and RNA in a 5’-3’ direction, and it can hydrolyze all deoxyribonucleotide and ribonucleotide triphosphates. Helicases are motor proteins that utilize the energy derived from nucleotide hydrolysisto unwind double-stranded nu...
TMPJ-00946	TALDO1 Protein, Human, Recombinant (His) Transaldolase,TALDO1,TAL,TALDOR,TALDO	Human	HEK293 Cells
	Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. TALDO1 deficiency results in telangiectases of the sk...
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cytidine monophosphate (UMP-CM...	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi...
TMPY-03286	hnRNP-R Protein, Human, Recombinant (His & GST) hnRNP-R,HNRPR,heterogeneous nuclear ribonucleoprotein R,HNRN...	Human	Baculovirus Insect Cells
	HNRNP R, also known as HNRNPR, is an RNA binding protein. HNRNP R gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). HnRNPs complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The ...
TMPY-03395	PC4/SUB1 Protein, Human, Recombinant (His) PC4,RPO2TC1,SUB1 homolog, transcriptional regulator,p14,SUB1...	Human	E. coli
	SUB1 belongs to the transcriptional coactivator PC4 family. It is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. SUB1 binds single-stranded DNA. Single-stranded DNA-binding proteins play many roles in nucleic acid metabolism, but their importance during transcription remains unclear. SUB1 exhibits strong genetic interactions with factors necessary for promoter melting. It loc...
TMPJ-00836	G6PD Protein, Human, Recombinant (His) Glucose-6-Phosphate 1-Dehydrogenase,G6PD	Human	HEK293 Cells
	Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the re...
TMPY-01595	PCBP1 Protein, Human, Recombinant (His) HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) binding protein 1,hn...	Human	E. coli
	Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr...

重组蛋白

RtcB Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00732

Species: E. coli

Expression System: P. pastoris (Yeast)

SARS-CoV-2 Helicase Protein (His & MBP)

Cat.No: TMPJ-01450

Species: SARS-CoV-2

Expression System: E. coli

TALDO1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00946

Species: Human

Expression System: HEK293 Cells

UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04480

Species: Human

Expression System: Baculovirus Insect Cells

hnRNP-R Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03286

Species: Human

Expression System: Baculovirus Insect Cells

PC4/SUB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03395

Species: Human

Expression System: E. coli

G6PD Protein, Human, Recombinant (His)

Cat.No: TMPJ-00836

Species: Human

Expression System: HEK293 Cells

PCBP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01595

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0166	Thymine-d4
	Thymine-d4 是 Thymine 的氘代化合物。Thymine 的 CAS 号为 65-71-4。Thymine 是 DNA 的四个碱基之一，在动物癌症模型中，能够作为5-氟尿嘧啶的靶标，其 Km=2.3 μM。
TMID-0167	6-Hydroxypurine-d4
	6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine，也被称为 purine-6-ol 或 Hyp，属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物，是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下，Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤，黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。

同位素标记化合物

Cat.No: TMID-0166

6-Hydroxypurine-d4

Cat.No: TMID-0167

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