|
TMPJ-01465
|
GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)
Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr...
|
Human
|
E. coli
|
|
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo... |
|
TMPJ-01210
|
IL-33 Protein, Mouse, Recombinant
Interleukin-1 family member 11,白细胞介素,NF-HEV and IL- 1F11,白介素...
|
Mouse
|
E. coli
|
|
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ... |
|
TMPY-01061
|
FGF-10 Protein, Human, Recombinant
fibroblast growth factor 10,KGF2
|
Human
|
E. coli
|
|
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla... |
|
TMPJ-00412
|
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Vascular endothelial growth factor receptor 1,Vascular perme...
|
Human
|
HEK293 Cells
|
|
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas... |
|
TMPH-02856
|
SAAL1 Protein, Mouse, Recombinant (His & Myc)
Synoviocyte proliferation-associated in collagen-induced art...
|
Mouse
|
E. coli
|
|
Plays a role in promoting the proliferation of synovial fibroblasts in response to proinflammatory stimuli. |
|
TMPH-00376
|
IL-8/CXCL8 Protein, Chicken, Recombinant
CEF-4,Embryo fibroblast protein 1,Chemokine (C-X-C motif) li...
|
Chicken
|
E. coli
|
|
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. IL-8/CXCL8 Protein, Chicken, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is P08317. |
|
TMPH-00375
|
IL-8/CXCL8 Protein, Chicken, Recombinant (His)
Embryo fibroblast protein 1,Interleukin-8,Chemokine (C-X-C m...
|
Chicken
|
E. coli
|
|
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. IL-8/CXCL8 Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is P08317. |
|
TMPH-02568
|
CTGF/CCN2 Protein, Mouse, Recombinant (GST)
betaIG-M2,Connective tissue growth factor,Protein FISP-12,Fi...
|
Mouse
|
E. coli
|
|
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
|
TMPK-00373
|
FAP Protein, Human, Recombinant (hFc)
FAPA,SIMP,DPPIV,FAPα,FAP,Seprase,FAPalpha,DPPIVA,APCE
|
Human
|
HEK293 Cells
|
|
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells. FAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 112.3 kDa and the accession number is Q12884-1. |
|
TMPH-01069
|
CTGF/CCN2 Protein, Human, Recombinant (His)
Hypertrophic chondrocyte-specific protein 24,CCN family memb...
|
Human
|
E. coli
|
|
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and... |
|
TMPK-00517
|
GAS6 Protein, Cynomolgus, Recombinant (His)
FLJ34709,AXLLG,GAS6,DKFZp666G247,GAS-6
|
Cynomolgus
|
HEK293 Cells
|
|
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM). |
|
TMPK-00923
|
FAP Protein, Mouse, Recombinant (His)
FAPα,FAPalpha,DPPIVA,APCE,SIMP,FAP,DPPIV,FAPA,Seprase
|
Mouse
|
HEK293 Cells
|
|
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells. FAP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 86.4 kDa and the accession number is P97321-1. |
|
TMPH-02507
|
Angiogenin-4 Protein, Mouse, Recombinant (His & Myc & SUMO)
EC:3.1.27.-,Angiogenin-4,Ang4
|
Mouse
|
E. coli
|
|
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). Angiogenin-4 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 31.4 kDa and the accession number is Q3TMQ6. |
|
TMPH-02508
|
Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar)
Ang4,Angiogenin-4,EC:3.1.27.-
|
Mouse
|
P. pastoris (Yeast)
|
|
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 29.9 kDa and the accession number is Q3TMQ6. |
|
TMPJ-00008
|
CXCL10 Protein, Human, Recombinant (hFc & His)
INP10,10 kDa Interferon Gamma-Induced Protein,C-X-C Motif Ch...
|
Human
|
HEK293 Cells
|
|
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity. |
|
TMPK-01282
|
FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
FAPα,DPPIVA,SIMP,APCE,DPPIV,Seprase,FAP,FAPA,FAPalpha
|
Cynomolgus
|
HEK293 Cells
|
|
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells. FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 88 kDa and the accession number is A0A2K5VGF4. |
|
TMPY-02602
|
PTPMT1 Protein, Human, Recombinant (His)
protein tyrosine phosphatase, mitochondrial 1,MOSP,FLJ46081,...
|
Human
|
E. coli
|
|
PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. It has been recently reported that PTPMT1 dephosphorylates phosphatidylglycerol phosphate, an essential intermediate of cardiolipin biosynthesis. PTPMT1 deficiency in mouse embryonic fibroblasts compromises mitochondrial respiration and results in abnormal mitochondrial morphology. Lipid analysis of PTPMT1-deficient fibroblasts reveals an a... |
|
TMPJ-01085
|
DPT Protein, Human, Recombinant (hFc & His)
TRAMP and DPT,Tyrosine-rich acidic matrix protein,Dermatopon...
|
Human
|
HEK293 Cells
|
|
Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. ... |
|
TMPJ-01308
|
ITPase Protein, Human, Recombinant (His)
Nucleoside-Triphosphate Diphosphatase,Nucleoside-Triphosphat...
|
Human
|
E. coli
|
|
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation... |
|
TMPY-05353
|
CCL26 Protein, Human, Recombinant
MIP-4alpha,SCYA26,MIP-4a,chemokine (C-C motif) ligand 26,IMA...
|
Human
|
Baculovirus Insect Cells
|
|
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3), which is also expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. The sequence similarity between the three eotaxins is limited (<4%), but their functional properties are very similar. Eotaxin-1 ... |
|
TMPY-02023
|
CD46 Protein, Human, Recombinant (His)
AHUS2,MIC10,CD46 molecule, complement regulatory protein,TLX...
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Human
|
HEK293 Cells
|
|
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic... |
|
TMPJ-00508
|
CTSL Protein, Human, Recombinant (His)
CTSL,CTSL1,Cathepsin L1,Major Excreted Protein,MEP
|
Human
|
HEK293 Cells
|
|
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the maj... |
|
TMPY-03853
|
DCBLD2 Protein, Human, Recombinant (His)
CLCP1,discoidin, CUB and LCCL domain containing 2,ESDN
|
Human
|
HEK293 Cells
|
|
DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor med... |
|
TMPJ-01107
|
PAP Protein, Human, Recombinant (His)
PAP1,PAP,PDGFA-Associated Protein 1,HASPP28,28 kDa Heat- and...
|
Human
|
E. coli
|
|
Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 sho... |
|
TMPJ-00073
|
FGF-7/KGF Protein, Human, Recombinant
Fibroblast growth factor 7,成纤维细胞生长因子,FGF-7,Heparin-binding g...
|
Human
|
E. coli
|
|
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in... |
|
TMPJ-00164
|
IGFBP-5 Protein, Human, Recombinant (His & Avi), Biotinylated
IBP-5,IBP5,IGF-Binding Protein 5,IGFBP5,Insulin-Like Growth ...
|
Human
|
HEK293 Cells
|
|
Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. They have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP-5 contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP-5 is expressed... |
|
TMPJ-00810
|
ITGA5 Protein, Human, Recombinant (His)
FNRA,Integrin α-5,Integrin Alpha-F,Fibronectin Receptor Subu...
|
Human
|
HEK293 Cells
|
|
Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the ext... |
|
TMPJ-01338
|
TSLP Protein, Mouse, Recombinant (hFc)
Thymic stromal lymphopoietin,Thymic stroma-derived lymphopoi...
|
Mouse
|
HEK293 Cells
|
|
Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells ... |
|
TMPY-04073
|
MRPL44 Protein, Human, Recombinant (His)
mitochondrial ribosomal protein L44,COXPD16,L44MT,MRP-L44
|
Human
|
Baculovirus Insect Cells
|
|
MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondrial ribosome. It belongs to the mitochondrion-specific ribosomal protein mL44 subfamily. In the patient fibroblasts, decreased MRPL44 affected assembly of the large ribosomal subunit and stability of 16S rRNA leading to complex IV deficiency. It may have a function in the assembly/... |
|
TMPY-01557
|
MAGOH Protein, Human, Recombinant (His)
MAGOHA,MAGOH1,mago-nashi homolog, proliferation-associated (...
|
Human
|
E. coli
|
|
MAGOH (Mago Homolog, Exon Junction Complex Subunit) is a Protein Coding gene. MAGOH is the human homolog of Drosophila mago nashi, a protein that is required for normal germplasm development in the Drosophila embryo. In mammals, mRNA expression is not limited to the germplasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. The exon junction complex (EJCs) are deposited on messenger RNAs (mRNAs) during splicing and their core consi... |
|
TMPJ-00006
|
CXCL1 Protein, Mouse, Recombinant (His)
Scyb1,Growth-regulated α,Mgsa,Gro1,Growth-regulated alpha pr...
|
Mouse
|
HEK293 Cells
|
|
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical ... |
|
TMPY-03987
|
T Plastin/PLS3 Protein, Human, Recombinant (His)
BMND18,T-plastin,plastin 3
|
Human
|
E. coli
|
|
PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, m... |
|
TMPJ-01004
|
HDGF Protein, Human, Recombinant (His)
HDGF,Hepatoma-Derived Growth Factor,HMG1L2,High Mobility Gro...
|
Human
|
E. coli
|
|
Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDG... |
|
TMPJ-00253
|
OPG Protein, Mouse, Recombinant (His)
Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory factor,Oste...
|
Mouse
|
HEK293 Cells
|
|
Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ... |
|
TMPJ-00361
|
Endoglin Protein, Human, Recombinant (Trx & His)
CD105,END,Endoglin,ENG
|
Human
|
E. coli
|
|
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins an... |
|
TMPJ-01286
|
proHB-EGF Protein, Human, Recombinant (His)
heparin-binding EGF-like growth factor,HB-EGF,HEGFL,DTS,Diph...
|
Human
|
HEK293 Cells
|
|
Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. Human HBEGF shows 76% and 73% aa sequence identity with rat and mouse HBEGF, respectively. It is required for normal cardiac valve formation and normal heart function, promotes smooth muscle cell proliferation. It may b... |
|
TMPJ-00012
|
CXCL4 Protein, Human, Recombinant (His)
SCYB4,PF4,Iroplact,Platelet Factor 4,PF-4,Oncostatin-A,CXCL4...
|
Human
|
HEK293 Cells
|
|
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokin... |
|
TMPJ-00028
|
CCL2 Protein, Mouse, Recombinant
Ccl2,Je,Mcp1,C-C motif chemokine 2,Platelet-derived growth f...
|
Mouse
|
E. coli
|
|
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equine, porcine, bovine and canine CCL2, respectively. Fibroblasts, glioma cells, smooth muscle cells, endothelial cells, lymphocytes and mononuclear phagocytes can produce CCL2 either constitutively or upon mitogenic stimulation, but monocytes and macrophages appear to be the major... |
|
TMPJ-00323
|
Nectin-2 Protein, Mouse, Recombinant (hFc)
Herpes Virus Entry Mediator B,PVRL2,Poliovirus Receptor-Rela...
|
Mouse
|
HEK293 Cells
|
|
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju... |
|
TMPJ-00438
|
SECTM1A Protein, Mouse, Recombinant (His)
Sectm1a
|
Mouse
|
HEK293 Cells
|
|
SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect h... |
|
TMPJ-01177
|
NOV/CCN3 Protein, Mouse, Recombinant (His)
CCN family member 3,Nephroblastoma-overexpressed gene protei...
|
Mouse
|
HEK293 Cells
|
|
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and ... |
|
TMPJ-00920
|
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
TNFSF5,Tumor necrosis factor ligand superfamily member 5,CD4...
|
Mouse
|
HEK293 Cells
|
|
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is upregulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and sm... |
|
TMPY-02120
|
XPNPEP2 Protein, Human, Recombinant (His)
AEACEI,X-prolyl aminopeptidase (aminopeptidase P) 2, membran...
|
Human
|
HEK293 Cells
|
|
Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution ... |
|
TMPJ-01082
|
IGFBP-5 Protein, Mouse, Recombinant (His)
IGFBP-5,IGF-binding protein 5,BP-5,Insulin-like growth facto...
|
Mouse
|
HEK293 Cells
|
|
Mouse Insulin-like growth factor-binding protein 5(IGFBP-5) belongs to the superfamily of insulin-like growth factor (IGF) binding proteins. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. Mouse IGFBP-5 shows 97% aa sequence identity with those of human and rat IGFBP-5. It is expressed mostly in kidney, uterus and gastrocnemius muscle. It also expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. IGFBP-5 has a strong... |
|
TMPJ-01337
|
IL-21R Protein, Mouse, Recombinant (aa 20-236, His)
Nilr,IL-21R,Interleukin-21 receptor,IL-21 receptor,Il21r
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Mouse
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HEK293 Cells
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Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i... |
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TMPJ-00835
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FGF-4 Protein, Mouse, Recombinant
HSTF1,HST-1,FGF4,FGF-4,HBGF-4,Fibroblast growth factor 4,HST...
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Mouse
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E. coli
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Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2... |
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TMPY-02757
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TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)
FN14,CD266,TWEAKR,tumor necrosis factor receptor superfamily...
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Human
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HEK293 Cells
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Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an extracellular domain, a membrane-anchoring domain, and a cytoplasmic domain. In response to FGF1, calf serum, or phorbol ester stimulation of human quiescent fibroblasts in vitro, the level of Fn14 is increased. A 1.2-kb FN14 transcript was expressed at high levels in heart, placent... |
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TMPY-01929
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ECE1 Protein, Human, Recombinant (His)
RP3-329E20.1,endothelin converting enzyme 1,ECE
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Human
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HEK293 Cells
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Endothelin-converting enzyme 1, also known as ECE-1, is a single-pass type II membrane protein which belongs to thepeptidase M13 family. ECE-1 converts big endothelin-1 to endothelin-1. ECE-1 is a membrane metalloprotease that generates endothelin from its direct precursor big endothelin. Four isoforms of ECE-1 are produced from a single gene through the use of alternate promoters. These isoforms share the same extracellular catalytic domain and contain unique cytosolic tails, which resul... |
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TMPJ-00831
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CCL3 Protein, Mouse, Recombinant (His)
LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha,LD78 alpha,chemokine (C-C ...
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Mouse
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E. coli
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C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra... |
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TMPY-02246
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HB-EGF Protein, Human, Recombinant
DTSF,DTR,HEGFL,heparin-binding EGF-like growth factor,DTS
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Human
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Baculovirus Insect Cells
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Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of... |
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