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Targets Recommended: Reductase

137

抑制剂 & 化合物

30

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1

化合物库

83

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5

同位素标记化合物

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Cat. No. Product Name
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Target Signaling Pathways
T2013 Ponalrestat

Reductase Endocrinology/Hormones; Metabolism
Ponalrestat 是一种口服有效的,选择性的和非竞争性的醛糖还原酶抑制剂,对 ALR2选择性选择性较高,Ki 为 7.7 nM, 对 ALR1 的选择性较弱,Ki 为 60 μM。Ponalrestat 抑制葡萄糖向山梨糖醇的转化。
T8490 Butoconazole

1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole,布康唑

Antifungal Microbiology/Virology
Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) 是一种咪唑类抗真菌药物,可治疗白色念珠菌引起的阴道感染。它可通过抑制类固醇起抗菌作用。
T13584 BMVC-8C3O

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
BMVC-8C3O 是一种 DNA G-四链体 (G4) 配体,可诱导人类端粒 DNA G4 中的非平行到平行形式的拓扑转换
T2061 APY0201

PI3K; Interleukin Immunology/Inflammation; PI3K/Akt/mTOR signaling
APY0201 是PIKfyve 抑制剂,能够抑制 PtdIns3P 转化为PtdIns(3,5)P2 (IC50:5.2 nM),还能够抑制IL-12/IL-23产生。
T2148 Carbidopa monohydrate

Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物

Decarboxylase; Aryl Hydrocarbon Receptor Immunology/Inflammation; Metabolism; Others
Carbidopa monohydrate (S(-)-Carbidopa) 是一种外周型脱羧酶抑制剂,可用于帕金森病的研究。它是一种选择性芳香烃受体 (AhR) 调节剂。它抑制胰腺癌细胞和肿瘤生长。
T3281 Delapril hydrochloride

indalapril,地拉普利盐酸盐,Alindapril Hydrochloride,Delapril Hydrochloride,盐酸地拉普利,CV 3317

RAAS Endocrinology/Hormones
Delapril hydrochloride (indalapril) 是一种血管紧张素转化酶抑制剂,能够用于心血管疾病的研究。
T77507 (-)-Benzotetramisole

Others Others
(-)-Benzotetramisole 使一种高效且具有选择性的催化剂。(-)-Benzotetramisole 是抗蠕虫化合物四咪唑3 的苯annulated 衍生物,本身也是转化的有效催化剂。
T4049 Genz-123346 free base

Glucokinase Metabolism
Genz-123346 free base 是一种能够阻断神经酰胺向GL1转化的GL1合酶的抑制剂,其抑制GM1的IC50值为14 nM。
T23550 YM-750

YM 750

Acyltransferase Metabolism
YM-750 是一种有效的酰基:胆固醇酰基转移酶(ACAT)抑制剂,IC50为0.18 μM。
T27832 Lifibrol

U 83860,K-12148,K-12.148,U-83860,K12148

Lipid Metabolism
Lifibrol (U-83860) 是一种胆固醇合成抑制剂。Lifibrol 具有抗胆固醇和降血脂的作用,可促进高胆固醇血症和混合型高脂血症患者体内低密度脂蛋白载脂蛋白 B-100 的转化。
T0961 Trometamol

三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵

COX Immunology/Inflammation; Neuroscience
Trometamol (Tromethamine) 是一种在生理范围内控制 pH 值的有效胺类化合物,也是一种低毒性的生物惰性氨基醇,可以在体内和体外缓冲二氧化碳和酸。
T1462 Captopril

SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333

RAAS Endocrinology/Hormones
Captopril (SA333) 是一种含巯基的,具有口服活性的血管紧张素转换酶(ACE)抑制剂 ,IC50=0.025 μM,广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是NDM-1抑制剂,IC50=7.9 μM。
T1736 Apixaban

阿哌沙班,BMS-562247-01

Factor Xa Metabolism
Apixaban (BMS-562247-01) 是一种高度选择性,可逆的、口服具有活力的凝血因子 Xa (Factor Xa) 抑制剂,抑制人和兔凝血因子 Xa 的 Ki 分别为 0.08 nM 和 0.17 nM。它可以用于研究各种血栓栓塞疾病。
T2134 Dorzolamide hydrochloride

MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl

Carbonic Anhydrase Metabolism
Dorzolamide hydrochloride (MK507 hydrochloride) 是一种碳酸酐酶carbonic anhydrase II 抑制剂,能够抑制红细胞CA-II(IC50:0.18 nM) 和CA-I(IC50:600 nM) 。
T8987 Epiblastin A

Casein Kinase Metabolism; Stem Cells
Epiblastin A 是 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂,能够抑制 CK1α (IC50:8.9 µM)、 CK1δ (IC50:0.5 µM)、CK1 ɛ (IC50:4.7 µM)。它能够抑制 CK1 诱导外胚层干细胞重编程为胚胎干细胞。
T1484L Perindopril erbumine

培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt

Apoptosis; RAAS; MRP Apoptosis; Endocrinology/Hormones; Immunology/Inflammation
Perindopril erbumine (S9490-3) 是一种长效血管紧张素转换酶抑制剂。
T1790 Fosaprepitant dimeglumine

福沙匹坦二甲葡胺,L785298,福沙吡坦二甲葡胺,MK-0517,Fosaprepitant dimeglumine salt

Neurokinin receptor GPCR/G Protein; Neuroscience
Fosaprepitant dimeglumine (MK-0517) 是 Aprepitant 的前药。它是一种神经激肽 1 受体拮抗剂,可用于预防化疗引起的恶心呕吐。
T20339 7-Hydroxymethotrexate

NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962

Drug Metabolite Metabolism
7-Hydroxymethotrexate 是 Methotrexate 主要的代谢产物。Methotrexate 对叶酸具有抑制作用,抑制二氢叶酸还原酶,从而防止叶酸转化为四氢叶酸,并抑制 DNA 合成。Methotrexate 对代谢也具有抑制作用。
T72814 11β-HSD1-IN-12

Dehydrogenase Metabolism
11β-HSD1-IN-12 是一种11β-HSD1抑制剂。11β-HSD1 可从非活性形式再生活性糖皮质激素,在调节细胞内糖皮质激素浓度方面很重要。11β-HSD1-IN-12 可用于肥胖和代谢综合征的研究。
T16510 PF-915275

Dehydrogenase Metabolism
PF-915275 是口服有效的人 11β-羟基类固醇脱氢酶1型选择性抑制剂,Ki 为 2.3 nM,在 HEK293 细胞中的EC50为 15 nM 。它对人和猴原代肝细胞中可的松向皮质醇的转化具有剂量依赖性,EC50分别为 20 nM 和 100 nM。
T77379 Bexmarilimab

FP-1305

Others Others
Bexmarilimab (FP-1305) 是一种高效的人源化抗 CLEVER-1 IgG4 抗体,其 IC50 值为 4.51 nM。Bexmarilimab 能够促使肿瘤相关巨噬细胞表型 M2 到 M1 的免疫转换。Bexmarilimab 可用于研究癌症。
T1438 Butoconazole nitrate

RS 35887,硝酸布康唑

Estrogen/progestogen Receptor; Antifungal Endocrinology/Hormones; Microbiology/Virology
Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物,可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。
T28482 Firibastat

QGC 001,QGC-001,RB-150,RB150,QGC001,RB 150

Aminopeptidase Metabolism
Firibastat (RB150) 是一种具有口服活性的 EC33 前体药物。Firibastat 是一种首创的脑氨基肽酶 A(APA) 抑制剂 (Ki=200 nM),选择性地抑制高血压大鼠脑血管紧张素 II 转化为血管紧张素 III,降低血压。
T0196 Diclofenac

双氯芬酸,奥尔芬,Diclofenacum,Voltaren

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Diclofenac (Diclofenacum) 是一种具有抗炎活性的非甾体苯乙酸衍生物,是 COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的 IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的 IC50值分别为 5.1 μM,0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。
T1184 Rivaroxaban

BAY 59-7939,利伐沙班

Factor Xa; Thrombin Metabolism; Proteases/Proteasome
Rivaroxaban (BAY 59-7939) 是高效选择性的凝血因子 Xa (FXa) 直接抑制剂,IC50=0.7 nM,Ki 为 0.4 nM。
T4281 Endoxifen

(E/Z)-N-desmethyl-4-hydroxy Tamoxifen,N-去甲基-4-羟基-,(E/Z)-Endoxifen

Estrogen Receptor/ERR; Aromatase; Estrogen/progestogen Receptor; Parasite; Drug Metabolite Endocrinology/Hormones; Metabolism; Microbiology/Virology
Endoxifen ((E/Z)-Endoxifen) 是 Tamoxifen 的关键活性代谢物,能抑制芳香酶的活性,与雌激素受体有较高的亲和力和特异性。它有潜力研究乳腺癌。
T1574 Etoricoxib

Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine,依托考昔

COX Immunology/Inflammation; Neuroscience
Etoricoxib (MK-663) 是一种合成的非甾体抗炎药 (NSAID),具有解热、镇痛和潜在的抗肿瘤特性。它是可口服的选择性 COX-2抑制剂,对人全血 COX-2 和 COX-1 的 IC50值分别为 1.1 和 116 μM。
T14878 CAY10566

Dehydrogenase; Stearoyl-CoA Desaturase (SCD) Metabolism
CAY10566 是选择性的、口服具有活性的硬脂酰辅酶 A 去饱和酶 1 抑制剂,在小鼠和人酶测定中IC50分别为 4.5 和 26 nM。它具有显著的细胞活性,可阻断 HepG2 细胞中饱和长链脂肪酸-CoAs (LCFA-CoAs) 向单不饱和 LCFA-CoAs 的转化 。
TP1115 L-Asparaginase

L-​ASNase

Others Others
L-Asparaginase (L-​ASNase) 是催化 L-天冬酰胺转化的水解酶,从血浆中去除 L-天冬酰胺,导致 RNA 和 DNA 合成抑制,随后引起细胞凋亡。它用于急性淋巴细胞白血病的研究。
T1185 Rofecoxib

MK 966,罗非昔布,罗非考昔,MK-0966

COX Immunology/Inflammation; Neuroscience
Rofecoxib (MK 966) 是可口服的 COX-2特异性抑制剂,具有抗炎、解热和镇痛特性以及潜在的抗肿瘤特性。在人骨肉瘤细胞和中国仓鼠卵巢细胞中,对人 COX-2 的 IC50值分别为 26 和 18 nM。
T1139 Salbutamol

Albuterol,沙丁胺醇,AH-3365

Adrenergic Receptor GPCR/G Protein; Neuroscience
Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。
T1676 Rosuvastatin

罗伐他汀,ZD 4522,瑞舒伐他汀

Potassium Channel; HMG-CoA Reductase; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Rosuvastatin (ZD 4522) 是一种抗血脂药,可竞争性抑制羟甲基戊二酰辅酶 A 还原酶,用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,IC50为 195 nM,延迟心脏复极化,延长动作电位持续时间和校正 QT 间期间隔。
T71703L Isomer-Turosteride

Isomer-Turosteride(Isomer-137099-09-3)

Reductase Endocrinology/Hormones; Metabolism
Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) 是一种新型 5α- 还原酶抑制剂。Isomer-Turosteride 在成年大鼠中的抗前列腺作用与抑制T向 DHT 的转化有关。Isomer-Turosteride引起前列腺 DHT 的降低,与 T 含量的继发性增加无关。Isomer-Turosteride 具有抗癌活性,可抑制肿瘤细胞的生长。
T4039 BIBB 515

Others Others
BIBB 515 是口服具有活力的 2,3-氧化角鲨烯环化酶选择性抑制剂,在大鼠和小鼠中的 ED50值分别为 0.2-0.5 mg/kg 和 0.36-33.3 mg/kg (1-5 小时)。它主要利用抑制低密度脂蛋白的产生,从而发挥降脂作用。
T37190 L-Allylglycine

Dehydrogenase; GABA Receptor Membrane transporter/Ion channel; Metabolism; Neuroscience
L-Allylglycine 是 GABA 合成酶(谷氨酸脱羧酶)的有效抑制剂。
T25127 Azalanstat

RS-21607,RS 21607,RS21607

Others Others
Azalanstat is a lanosterol 14 alpha-demethylase inhibitor. The enzyme catalyzes the first step in the conversion of lanosterol to cholesterol in mammals.
T32539 Laidlomycin propionate

Others Others
Laidlomycin propionate improves the rate of gain and feed conversion in both steers and heifers.
T1574L Etoricoxib HCl

L-791456 monohydrochloride salt,L791456 hydrochloride,L-791456 hydrochloride,L 791456 hydrochloride,Etoricoxib hydrochloride

Others Others
Etoricoxib HCl is a synthetic, nonsteroidal anti-inflammatory drug. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2, resulting in inhibition of the conversion of arachidonic acid into prostaglandins.
T3281L Delapril

Alindapril

Others Others
Delapril is an ACE inhibitor. It blocks the conversion of angiotensin I to angiotensin II.
T40841 L-2-Aminooxy-3-phenylpropanoic acid hydrobromide

Others Others
L-2-Aminooxy-3-phenylpropanoic acid hydrobromide is a powerful inhibitor of L-phenylalanine ammonia-lyase, an enzyme responsible for catalyzing the conversion of L-phenylalanine to trans-cinnamic acid.
T70209 Nepicastat hydrochloride monohydrate

Others Others
Nepicastat hydrochloride monohydrate is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.
T11070L DO34

Others Others
DO34 is a highly potent and centrally active inhibitor of diacylglycerol lipase (IC50: 6 nM for DAGLα conversion of SAG to 2-AG).
T40852 (Rac)-γ-Tocopherol

(Rac)-γ-Tocopherol,DMPBQ

Others Others
(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.
T1517L Benserazide

Ro-44602,Ro44602,Ro 44602,Serazide

Others Others
Benserazide is an inhibitor of dopa decarboxylase. It is often given with levodopa in the treatment of Parkinson's to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system an
T27119 Daglutril

SLV306,SLV 306,SLV-306

Others Others
Daglutril, a NEP/ECE inhibitor, is potentially used for the treatment of hypertension, heart failure andpulmonary. Daglutril inhibits systemic conversion of big endothelin-1 in humans.
T76115 Pyruvate kinase

Others Others
Pyruvate kinase 是一种糖酵解酶,催化磷酸烯醇式丙酮酸和 ADP 转化为丙酮酸和 ATP。
T85007 10(S)-HOME

HOD

Others Others
10(S)-HOME, an oxylipin, acts as an intermediate in the conversion process of oleic acid into the antibacterial hydroxy fatty acid 7,10-dihydroxy-8(E)-octadecenoic acid within P. aeruginosa.
T34084 Plastoquinone

Q 254,Q-254,Q254

Others Others
Plastoquinone is a polyunsaturated side-chain quinone derivative which is an important link in the electron transport chain of green plants during the photosynthetic conversion of light energy by photophosphorylation into the potential energy of chemical
T76106 Glycerol phosphate dehydrogenase

Others Others
Glycerol phosphate dehydrogenase 催化磷酸二羟丙酮转化为 α-甘油磷酸。
T11389 Genz-123346

Others Others
Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM. Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor.

化合物

Ponalrestat
Cat.No: T2013
Synonym:
Target: Reductase
Butoconazole
Cat.No: T8490
Synonym: 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole,布康唑
Target: Antifungal
BMVC-8C3O
Cat.No: T13584
Synonym:
Target: DNA/RNA Synthesis
APY0201
Cat.No: T2061
Synonym:
Target: PI3K, Interleukin
Carbidopa monohydrate
Cat.No: T2148
Synonym: Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物
Target: Decarboxylase, Aryl Hydrocarbon Receptor
Delapril hydrochloride
Cat.No: T3281
Synonym: indalapril,地拉普利盐酸盐,Alindapril Hydrochloride,Delapril Hydrochloride,盐酸地拉普利,CV 3317
Target: RAAS
(-)-Benzotetramisole
Cat.No: T77507
Synonym:
Target: Others
Genz-123346 free base
Cat.No: T4049
Synonym:
Target: Glucokinase
YM-750
Cat.No: T23550
Synonym: YM 750
Target: Acyltransferase
Lifibrol
Cat.No: T27832
Synonym: U 83860,K-12148,K-12.148,U-83860,K12148
Target: Lipid
Trometamol
Cat.No: T0961
Synonym: 三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵
Target: COX
Captopril
Cat.No: T1462
Synonym: SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333
Target: RAAS
Apixaban
Cat.No: T1736
Synonym: 阿哌沙班,BMS-562247-01
Target: Factor Xa
Dorzolamide hydrochloride
Cat.No: T2134
Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl
Target: Carbonic Anhydrase
Epiblastin A
Cat.No: T8987
Synonym:
Target: Casein Kinase
Perindopril erbumine
Cat.No: T1484L
Synonym: 培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt
Target: Apoptosis, RAAS, MRP
Fosaprepitant dimeglumine
Cat.No: T1790
Synonym: 福沙匹坦二甲葡胺,L785298,福沙吡坦二甲葡胺,MK-0517,Fosaprepitant dimeglumine salt
Target: Neurokinin receptor
7-Hydroxymethotrexate
Cat.No: T20339
Synonym: NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962
Target: Drug Metabolite
11β-HSD1-IN-12
Cat.No: T72814
Synonym:
Target: Dehydrogenase
PF-915275
Cat.No: T16510
Synonym:
Target: Dehydrogenase
Bexmarilimab
Cat.No: T77379
Synonym: FP-1305
Target: Others
Butoconazole nitrate
Cat.No: T1438
Synonym: RS 35887,硝酸布康唑
Target: Estrogen/progestogen Receptor, Antifungal
Firibastat
Cat.No: T28482
Synonym: QGC 001,QGC-001,RB-150,RB150,QGC001,RB 150
Target: Aminopeptidase
Diclofenac
Cat.No: T0196
Synonym: 双氯芬酸,奥尔芬,Diclofenacum,Voltaren
Target: Apoptosis, COX
Rivaroxaban
Cat.No: T1184
Synonym: BAY 59-7939,利伐沙班
Target: Factor Xa, Thrombin
Endoxifen
Cat.No: T4281
Synonym: (E/Z)-N-desmethyl-4-hydroxy Tamoxifen,N-去甲基-4-羟基-,(E/Z)-Endoxifen
Target: Estrogen Receptor/ERR, Aromatase, Estrogen/progestogen Receptor, Parasite, Drug Metabolite
Etoricoxib
Cat.No: T1574
Synonym: Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine,依托考昔
Target: COX
CAY10566
Cat.No: T14878
Synonym:
Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)
L-Asparaginase
Cat.No: TP1115
Synonym: L-​ASNase
Target: Others
Rofecoxib
Cat.No: T1185
Synonym: MK 966,罗非昔布,罗非考昔,MK-0966
Target: COX
Salbutamol
Cat.No: T1139
Synonym: Albuterol,沙丁胺醇,AH-3365
Target: Adrenergic Receptor
Rosuvastatin
Cat.No: T1676
Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
Isomer-Turosteride
Cat.No: T71703L
Synonym: Isomer-Turosteride(Isomer-137099-09-3)
Target: Reductase
BIBB 515
Cat.No: T4039
Synonym:
Target: Others
L-Allylglycine
Cat.No: T37190
Synonym:
Target: Dehydrogenase, GABA Receptor
Azalanstat
Cat.No: T25127
Synonym: RS-21607,RS 21607,RS21607
Target: Others
Laidlomycin propionate
Cat.No: T32539
Synonym:
Target: Others
Etoricoxib HCl
Cat.No: T1574L
Synonym: L-791456 monohydrochloride salt,L791456 hydrochloride,L-791456 hydrochloride,L 791456 hydrochloride,Etoricoxib hydrochloride
Target: Others
Delapril
Cat.No: T3281L
Synonym: Alindapril
Target: Others
L-2-Aminooxy-3-phenylpropanoic acid hydrobromide
Cat.No: T40841
Synonym:
Target: Others
Nepicastat hydrochloride monohydrate
Cat.No: T70209
Synonym:
Target: Others
DO34
Cat.No: T11070L
Synonym:
Target: Others
(Rac)-γ-Tocopherol
Cat.No: T40852
Synonym: (Rac)-γ-Tocopherol,DMPBQ
Target: Others
Benserazide
Cat.No: T1517L
Synonym: Ro-44602,Ro44602,Ro 44602,Serazide
Target: Others
Daglutril
Cat.No: T27119
Synonym: SLV306,SLV 306,SLV-306
Target: Others
Pyruvate kinase
Cat.No: T76115
Synonym:
Target: Others
10(S)-HOME
Cat.No: T85007
Synonym: HOD
Target: Others
Plastoquinone
Cat.No: T34084
Synonym: Q 254,Q-254,Q254
Target: Others
Glycerol phosphate dehydrogenase
Cat.No: T76106
Synonym:
Target: Others
Genz-123346
Cat.No: T11389
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4888 Phosphocreatine disodium hydrate

磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate

Others; Endogenous Metabolite Metabolism; Others
Phosphocreatine disodium hydrate 是内源性代谢产物的一种。
T3793 (20R)-Ginsenoside Rh1

20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1

Others Others
(20R)-Ginsenoside Rh1 (20(R)-Ginsenoside Rh1) 是 Ginsenoside Rh1 的 R 型异构体,分离自 Panax Ginseng 中,能够阻碍凝血酶诱导的纤维蛋白原向纤维蛋白的转化。
T20255 L-Galactose

Galactose, L-

Endogenous Metabolite Metabolism
L-Galactose (Galactose, L-) 是一种天然产物,广泛存在动植物体内。L-Galactose 在Pistia stratiotes 中被证明是D-葡萄糖转化为草酸的分子途径中的关键中间体。
T4929 L-2-Phosphoglyceric acid

L-GLYCERATE 3-PHOSPHATE 二钠盐,L-2-Phosphoglyceric acid disodium salt h

Others; Endogenous Metabolite Metabolism; Others
L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) 是内源性代谢产物的一种。
T5755 Aloesin

Tyrosinase Proteases/Proteasome
Aloesin 是芦荟的活性成分之一,能够通过 MAPK 信号通路发挥抗癌作用,并具有抗炎、紫外线保护和抗菌作用。
T0610 Piceatannol

白皮杉醇,trans-Piceatannol,Astringenin

Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
Piceatannol (Astringenin) 是一种Syk 抑制剂,可降低由 TNF 诱导的 iNOS 表达,可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯,可诱导细胞自噬和凋亡,具有抗癌和抗炎特性。
T4811 D-Alanine

D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid

Chloride channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
D-Alanine ((R)-Alanine) 是一种GlyR 和PMBA 的弱激动剂,其对GlyR 的EC50=9 mM。
T4726 D-Glucose 6-phosphate sodium

G6P sodium salt,D-Glucose 6-phosphate sodium salt,D-葡萄糖-6-磷酸钠盐,Sodium Glucose-6-Phosphate

Others; Endogenous Metabolite Metabolism; Others
D-Glucose 6-phosphate sodium (G6P sodium salt) 是内源性代谢产物的一种。
T1664 Meglutol

Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托

Endogenous Metabolite; HMG-CoA Reductase; Autophagy Autophagy; Metabolism
Meglutol (3-Hydroxy-3-methylglutaric acid) 是一种抗血脂剂,可降低胆固醇、甘油三酯、血清 β-脂蛋白和磷脂。它抑制胆固醇生物合成中的限速酶羟甲基戊二酰辅酶 A 还原酶的活性。
T10938 D-Kynurenine

D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103

GPR; AhR; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。
T4887 3-Amino-2-methylpropanoic acid

DL-3-AMINOISOBUTYRIC ACID,3-氨基异丁酸,α-Methyl-β-alanine

Endogenous Metabolite Metabolism
3-Amino-2-methylpropanoic acid (α-Methyl-β-alanine) 是 N-carbamyl-beta-aminoisobutyric acid 经 enzyme Beta-ureidopropionase (EC 3.5.1.6)转化后的产物,是嘧啶降解的最后一步。-尿嘧啶丙酸酶缺乏症是一种与神经异常相关的嘧啶降解的先天性错误。
T5069 D-Glucose 6-phosphate potassium salt

Others Others
在细胞中,当葡萄糖被己糖激酶或葡萄糖激酶磷酸化或在糖原分解过程中通过磷酸葡萄糖变位酶转化葡萄糖 1-磷酸时,会产生D-glucose 6-phosphate (G6P)。 G6P 位于糖酵解和戊糖磷酸途径的起点。当血糖水平高时,它也可以作为糖原储存。
T3578 Pyridoxal phosphate

PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Reverse Transcriptase; Endogenous Metabolite Metabolism; Microbiology/Virology
Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式,可抑制逆转录酶活性,用于研究迟发性运动障碍症。
T5079 Adenosine 5'-diphosphate sodium salt

腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Others; Endogenous Metabolite Metabolism; Others
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸,是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T2P2923 Stearic acid

硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid

Phosphatase; Endogenous Metabolite Metabolism
Stearic acid (Cetylacetic acid) 是长链饱和脂肪酸,存在于许多动植物油脂中。
T1591 Ancitabine hydrochloride

NSC 145668 HCl,盐酸环胞苷,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C

Others; DNA/RNA Synthesis; Autophagy Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
Ancitabine hydrochloride (NSC 145668 HCl) 是一种天然的抗白血病药物。
T4877 L-Homocystine

Endogenous Metabolite Metabolism
L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子,也是研究心血管疾病发生机制的内质网应激反应的诱导剂。
T4858 4-​Hydroxyphenylpyruvic acid

4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid

Endogenous Metabolite Metabolism
4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物,是一种酶抑制剂。
TN2769 2-Hydroxynaringenin

Others Others
The recombinant protein exhibits high FNS I activity catalyzing the conversion of naringenin to apigenin and 2-Hydroxynaringenin.
T37774 Thielavin A

Others Others
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).
TN1655 Ganoderal A

Others Others
The oxygenated sterols( 26-oxygenosterols ganoderol A, ganoderol B, ganoderal A, and ganoderic acid Y) from G. lucidum can inhibit cholesterol biosynthesis via conversion of acetate or mevalonate as a precursor of cholesterol.
T82445 Erinacine P

Erinacine P(化合物1)为担子菌猴头菇YB4-6237菌丝体分离得到的木犀草素亲代代谢产物。其在温和条件下可化学转化为猴头素B,继而可转化为猴头素A。
T78471 α,α-Trehalose 6-phosphate potassium

Tre6P potassium

Endogenous Metabolite Metabolism
α,α-Trehalose 6-phosphate (Tre6P) potassium 是一种α,α′-trehalose的6-磷酸衍生物及内源代谢物。在Tre6P磷酸酶 (T6PP) 的催化下,α,α-Trehalose 6-phosphate可被高效转化为α,α′-trehalose。
TN1751 Hydroxycitric acid

ERK; p38 MAPK; Fatty Acid Synthase MAPK; Metabolism
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis.
T35710 N-Acetyl-S-allyl-L-cysteine

Others Others
L-Deoxyalliin , also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities. N-Acetyl-S-allyl-L-cysteine is a principal metabolite of L-deoxyalliin in humans, mice, rats, and dogs. It is readily detected in plasma and urine. The conversion of L-deoxyalliin to N-acetyl-S-allyl-L-cysteine appears to be mediated by a family of flavin-containing monooxygenases.
T83416 2-(Methylamino)benzoic acid

N-Methylanthranilic acid

2-(Methylamino)benzoic acid 为 methyl-N-methylanthranilates (MMA) 的主要代谢物,系通过酯基转化形成。此化合物可从柑橘中提取,并具备潜在的镇痛功能。2-(Methylamino)benzoic acid 亦应用于监测大鼠肝脏中 MMA 的代谢情况。
T35415 α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

Others Others
α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...
T75576 Solidagonic acid

Others Others
Solidagonic acid 通过促进异常单极纺锤体向双极纺锤体的转变来抑制 HSET 运动活动。Solidagonic acid 抑制裂殖酵母细胞死亡,并使有丝分裂纺锤体从单极形态逆转为双极形态。Solidagonic acid 对 Lactuca sativaL. 和 Lolium multiflorumLam 的幼苗具有生长抑制活性。
T5141 L-2-Phosphoglyceric acid disodium salt hydrate

L-2-Phosphoglyceric acid 二钠盐水合物

Others Others
L-2-Phosphoglyceric acid disodium salt hydrate 是一种甘油酸,可作为糖酵解第九步的底物。它被烯醇化酶催化为磷酸烯醇式丙酮酸 (PEP),这是葡萄糖转化为丙酮酸的倒数第二个步骤。
T37452 Stephacidin B

Others Others
Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...

天然产物

Phosphocreatine disodium hydrate
Cat.No: T4888
Synonym: 磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate
Target: Others, Endogenous Metabolite
(20R)-Ginsenoside Rh1
Cat.No: T3793
Synonym: 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1
Target: Others
L-Galactose
Cat.No: T20255
Synonym: Galactose, L-
Target: Endogenous Metabolite
L-2-Phosphoglyceric acid
Cat.No: T4929
Synonym: L-GLYCERATE 3-PHOSPHATE 二钠盐,L-2-Phosphoglyceric acid disodium salt h
Target: Others, Endogenous Metabolite
Aloesin
Cat.No: T5755
Synonym:
Target: Tyrosinase
Piceatannol
Cat.No: T0610
Synonym: 白皮杉醇,trans-Piceatannol,Astringenin
Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy
D-Alanine
Cat.No: T4811
Synonym: D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid
Target: Chloride channel, Endogenous Metabolite
D-Glucose 6-phosphate sodium
Cat.No: T4726
Synonym: G6P sodium salt,D-Glucose 6-phosphate sodium salt,D-葡萄糖-6-磷酸钠盐,Sodium Glucose-6-Phosphate
Target: Others, Endogenous Metabolite
Meglutol
Cat.No: T1664
Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托
Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy
D-Kynurenine
Cat.No: T10938
Synonym: D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103
Target: GPR, AhR, Endogenous Metabolite
3-Amino-2-methylpropanoic acid
Cat.No: T4887
Synonym: DL-3-AMINOISOBUTYRIC ACID,3-氨基异丁酸,α-Methyl-β-alanine
Target: Endogenous Metabolite
D-Glucose 6-phosphate potassium salt
Cat.No: T5069
Synonym:
Target: Others
Pyridoxal phosphate
Cat.No: T3578
Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate
Target: Reverse Transcriptase, Endogenous Metabolite
Adenosine 5'-diphosphate sodium salt
Cat.No: T5079
Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt
Target: Others, Endogenous Metabolite
Stearic acid
Cat.No: T2P2923
Synonym: 硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid
Target: Phosphatase, Endogenous Metabolite
Ancitabine hydrochloride
Cat.No: T1591
Synonym: NSC 145668 HCl,盐酸环胞苷,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C
Target: Others, DNA/RNA Synthesis, Autophagy
L-Homocystine
Cat.No: T4877
Synonym:
Target: Endogenous Metabolite
4-​Hydroxyphenylpyruvic acid
Cat.No: T4858
Synonym: 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid
Target: Endogenous Metabolite
2-Hydroxynaringenin
Cat.No: TN2769
Synonym:
Target: Others
Thielavin A
Cat.No: T37774
Synonym:
Target: Others
Ganoderal A
Cat.No: TN1655
Synonym:
Target: Others
Erinacine P
Cat.No: T82445
Synonym:
Target:
α,α-Trehalose 6-phosphate potassium
Cat.No: T78471
Synonym: Tre6P potassium
Target: Endogenous Metabolite
Hydroxycitric acid
Cat.No: TN1751
Synonym:
Target: ERK, p38 MAPK, Fatty Acid Synthase
N-Acetyl-S-allyl-L-cysteine
Cat.No: T35710
Synonym:
Target: Others
2-(Methylamino)benzoic acid
Cat.No: T83416
Synonym: N-Methylanthranilic acid
Target:
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
Cat.No: T35415
Synonym:
Target: Others
Solidagonic acid
Cat.No: T75576
Synonym:
Target: Others
L-2-Phosphoglyceric acid disodium salt hydrate
Cat.No: T5141
Synonym: L-2-Phosphoglyceric acid 二钠盐水合物
Target: Others
Stephacidin B
Cat.No: T37452
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-01108 Factor VII Protein, Human, Recombinant (His & SUMO)

F7,Serum prothrombin conversion accelerator,Proconv...

Human E. coli
Factor VII Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-02014 Coagulation factor VII/F7 Protein, Human, Recombinant (His)

coagulation factor VII (serum prothrombin conversion

Human HEK293 Cells
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is ...
TMPH-01225 DHODH Protein, Human, Recombinant (His)

DHOdehase,DHODH,Dihydroorotate oxidase,Dihydroorotate dehydr...

Human E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-00857 ABAT Protein, Human, Recombinant (His & Myc & SUMO)

L-AIBAT,GABA aminotransferase,GABA transaminase,GABA-T,(S)-3...

Human E. coli
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. ABAT Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 73.3 kDa and the accession number is P80404.
TMPH-00007 HMGCR Protein, Human, Recombinant (His)

HMGCR,3-hydroxy-3-methylglutaryl-coenzyme A reductase

Human E. coli
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
TMPY-02483 ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

ATPCL,ACL,ATP citrate lyase,CLATP

Human Baculovirus Insect Cells
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show...
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G11Rik,9430067E15Rik,lysyl oxidase-like...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His)

coagulation factor 11,coagulation factor XI,FXI

Human HEK293 Cells
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ...
TMPH-00693 L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His)

lldD,L-lactate dehydrogenase

E. coli E. coli
Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
TMPJ-00496 PGM2 Protein, Human, Recombinant (His)

Phosphopentomutase,Phosphodeoxyribomutase,Glucose phosphomut...

Human E. coli
Phosphoglucomutase-2 (PGM2) is a member of PGM family, which catalyzes the inter-conversion of sugar phosphates and participates in anabolic and catabolic reactions. When cells are grown in glucose, PGM catalyzes the conversion of glucose-6-phosphate to glucose-1-phosphate an important precursor required for the synthesis of UDP glucose and trehalose. PGM2 catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphope...
TMPH-02627 DHODH Protein, Mouse, Recombinant (E. coli, His)

Dihydroorotate oxidase,DHODH,Dihydroorotate dehydrogenase (q...

Mouse E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-03278 DHODH Protein, Rat, Recombinant (His)

DHODH,DHOdehase,Dihydroorotate dehydrogenase (quinone), mito...

Rat E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-01608 DCT Protein, Human, Recombinant (His & Myc & SUMO)

DT,TYRP2,Tyrosinase-related protein 2,L-dopachrome Delta-iso...

Human E. coli
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
TMPH-02850 DHODH Protein, Mouse, Recombinant (His)

Dihydroorotate oxidase,Dihydroorotate dehydrogenase (quinone...

Mouse E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-00843 HSD11B1 Protein, Human, Recombinant (His & SUMO)

7-oxosteroid reductase,11-beta-hydroxysteroid dehydrogenase ...

Human E. coli
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol. HSD11B1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.5 kDa and the accession number is P28845.
TMPH-00757 Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His)

BBE1,Tetrahydroprotoberberine synthase,Berberine bridge-form...

Eschscholzia californica E. coli
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
TMPH-02751 DCT Protein, Mouse, Recombinant (His & SUMO)

TRP2,L-dopachrome Delta-isomerase,TRP-2,TYRP2,L-dopachrome t...

Mouse E. coli
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). DCT Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 69.7 kDa and the accession number is P29812.
TMPH-00578 NrdD Protein, E. coli, Recombinant (His)

nrdD,Class III ribonucleoside-triphosphate reductase,Anaerob...

E. coli E. coli
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.0 kDa and the accession number is P28903.
TMPH-02626 DLAT Protein, Mouse, Recombinant (His)

Pyruvate dehydrogenase complex component E2,Dlat,Dihydrolipo...

Mouse HEK293 Cells
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
TMPH-03654 Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase,OP...

VACV E. coli
Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response. Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...
TMPH-02299 UGP2 Protein, Human, Recombinant (His & SUMO)

UDP-glucose pyrophosphorylase,UTP--glucose-1-phosphate uridy...

Human E. coli
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.
TMPH-02625 DLAT Protein, Mouse, Recombinant (E. coli, His)

Dihydrolipoyllysine-residue acetyltransferase component of p...

Mouse E. coli
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. DLAT Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 62.8 kDa and the accession number is Q8BMF4.
TMPH-00074 GlcNAcT-I  Protein, Arabidopsis thaliana, Recombinant (His)

N-acetylglucosaminyltransferase I,Protein COMPLEX GLYCAN LES...

Arabidopsis thaliana Baculovirus Insect Cells
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Required for normal root growth and morphology. GlcNAcT-I  Protein, Arabidopsis thaliana, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is Q9XGM8.
TMPH-00404 Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His)

AADase,EC:4.1.1.4,ADC,AAD

Clostridium acetobutylicum Baculovirus Insect Cells
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide. Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is P23670.
TMPH-02643 Enteropeptidase Protein, Mouse, Recombinant (His & Myc)

Serine protease 7,Prss7,Transmembrane protease serine 15,Ent...

Mouse HEK293 Cells
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
TMPH-01862 PFAS Protein, Human, Recombinant (His & Myc & SUMO)

Phosphoribosylformylglycinamidine synthase,Formylglycinamide...

Human E. coli
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. PFAS Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 45.4 kDa and the accession number is O15067.
TMPH-00167 L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc)

L-arabinose isomerase,araA

Bacillus subtilis E. coli
Catalyzes the conversion of L-arabinose to L-ribulose. L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 63.6 kDa and the accession number is P94523.
TMPH-01601 Lactoylglutathione lyase/GLO1 Protein, Human, Recombinant (GST)

Ketone-aldehyde mutase,Glyoxalase I,Lactoylglutathione lyase...

Human E. coli
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.
TMPH-00689 Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc)

tdcD,Propionate kinase

E. coli E. coli
Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.4 kDa and the accession number is P59244.
TMPH-00575 GlpD Protein, E. coli, Recombinant (His)

glpD,Aerobic glycerol-3-phosphate dehydrogenase

E. coli E. coli
Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor. GlpD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 60.8 kDa and the accession number is P13035.
TMPH-00844 HSD11B2 Protein, Human, Recombinant (His)

HSD11B2,11-beta-hydroxysteroid dehydrogenase type 2,Short ch...

Human P. pastoris (Yeast)
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365.
TMPJ-00955 MDH1 Protein, Human, Recombinant (His)

Cytosolic Malate Dehydrogenase,MDH1,MDHA,Diiodophenylpyruvat...

Human E. coli
Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted up...
TMPH-03198 MGAT1 Protein, Rabbit, Recombinant (His & Myc)

MGAT1,Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosa...

Rabbit E. coli
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. MGAT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.2 kDa and the accession number is P27115.
TMPH-00667 OGDC-E2 Protein, E. coli O157:H7, Recombinant (His)

Dihydrolipoamide succinyltransferase component of 2-oxogluta...

E. coli E. coli
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). OGDC-E2 Protein, E. coli O157:H7, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P0AFG7.
TMPH-03260 Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc)

Cpa1,Carboxypeptidase A1,Cpa

Rat E. coli
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond. Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.6 kDa and the accession number is P00731.
TMPH-02644 Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)

Tmprss15,Entk,Enterokinase,Serine protease 7,Prss7,Transmemb...

Mouse E. coli
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Enteropeptidase Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P97435.
TMPH-02476 HMGCR Protein, Mouse, Recombinant (His)

Hmgcr,3-hydroxy-3-methylglutaryl-coenzyme A reductase

Mouse E. coli
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.4 kDa and the accession number is Q01237.
TMPJ-00479 KHK Protein, Human, Recombinant (His)

KHK,Hepatic fructokinase,Ketohexokinase

Human HEK293 Cells
Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.
TMPH-02246 TGS1 Protein, Human, Recombinant (His & SUMO)

CLL-associated antigen KW-2,Cap-specific guanine-N2 methyltr...

Human E. coli
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
TMPJ-00690 PGDS Protein, Human, Recombinant

Glutathione-Requiring Prostaglandin D Synthase,PGDS,Glutathi...

Human E. coli
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop...
TMPY-04767 PMVK Protein, Human, Recombinant (His)

PMK,PMKA,phosphomevalonate kinase,HUMPMKI,PMKASE

Human E. coli
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
TMPJ-01092 MGAT2 Protein, Human, Recombinant (His)

Alpha-1,Mannoside Acetylglucosaminyltransferase 2,6-Mannosyl...

Human HEK293 Cells
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
TMPY-03617 GMPR Protein, Human, Recombinant (His)

GMPR1,guanosine monophosphate reductase

Human E. coli
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
TMPH-02908 AICDA Protein, Mouse, Recombinant (His & Myc)

Single-stranded DNA cytosine deaminase,Cytidine aminohydrola...

Mouse E. coli
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
TMPJ-01368 GPC1 Protein, Mouse, Recombinant (His)

Gpc1,Glypican-1

Mouse HEK293 Cells
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated sig...
TMPJ-00989 MTHFS Protein, Human, Recombinant (His)

5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro...

Human E. coli
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas...
TMPJ-00724 LDHA Protein, Human, Recombinant (His)

LDH-M,Renal Carcinoma Antigen NY-REN-59,Cell Proliferation-I...

Human E. coli
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
TMPY-04762 CKM Protein, Human, Recombinant (His)

creatine kinase, muscle,M-CK,CKMM

Human E. coli
CKM, also known as CK-MM, is mainly expressed in skeletal muscle. As the primary CK isoenzyme, it also can be detected in heart muscle. CKM is a subunit of creatine kinase (CK). CK is an enzyme expressed by various tissues and cell types. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). In the cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type).
TMPJ-00788 UROD Protein, Human, Recombinant (His)

UPD,UROD,Uroporphyrinogen Decarboxylase,URO-D

Human E. coli
Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen...
TMPH-01391 GPI Protein, Human, Recombinant (His)

Sperm antigen 36,Neuroleukin,Glucose-6-phosphate isomerase,G...

Human E. coli
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. GPI Protein, Huma...
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重组蛋白

Factor VII Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01108
Species: Human
Expression System: E. coli
Coagulation factor VII/F7 Protein, Human, Recombinant (His)
Cat.No: TMPY-02014
Species: Human
Expression System: HEK293 Cells
DHODH Protein, Human, Recombinant (His)
Cat.No: TMPH-01225
Species: Human
Expression System: E. coli
ABAT Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00857
Species: Human
Expression System: E. coli
HMGCR Protein, Human, Recombinant (His)
Cat.No: TMPH-00007
Species: Human
Expression System: E. coli
ATP citrate lyase/ACLY Protein, Human, Recombinant (His)
Cat.No: TMPY-02483
Species: Human
Expression System: Baculovirus Insect Cells
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
Cat.No: TMPY-01104
Species: Human
Expression System: HEK293 Cells
L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His)
Cat.No: TMPH-00693
Species: E. coli
Expression System: E. coli
PGM2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00496
Species: Human
Expression System: E. coli
DHODH Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02627
Species: Mouse
Expression System: E. coli
DHODH Protein, Rat, Recombinant (His)
Cat.No: TMPH-03278
Species: Rat
Expression System: E. coli
DCT Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01608
Species: Human
Expression System: E. coli
DHODH Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02850
Species: Mouse
Expression System: E. coli
HSD11B1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00843
Species: Human
Expression System: E. coli
Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His)
Cat.No: TMPH-00757
Species: Eschscholzia californica
Expression System: E. coli
DCT Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02751
Species: Mouse
Expression System: E. coli
NrdD Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00578
Species: E. coli
Expression System: E. coli
DLAT Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02626
Species: Mouse
Expression System: HEK293 Cells
Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)
Cat.No: TMPH-03654
Species: VACV
Expression System: E. coli
UGP2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02299
Species: Human
Expression System: E. coli
DLAT Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02625
Species: Mouse
Expression System: E. coli
GlcNAcT-I  Protein, Arabidopsis thaliana, Recombinant (His)
Cat.No: TMPH-00074
Species: Arabidopsis thaliana
Expression System: Baculovirus Insect Cells
Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His)
Cat.No: TMPH-00404
Species: Clostridium acetobutylicum
Expression System: Baculovirus Insect Cells
Enteropeptidase Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02643
Species: Mouse
Expression System: HEK293 Cells
PFAS Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01862
Species: Human
Expression System: E. coli
L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc)
Cat.No: TMPH-00167
Species: Bacillus subtilis
Expression System: E. coli
Lactoylglutathione lyase/GLO1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01601
Species: Human
Expression System: E. coli
Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc)
Cat.No: TMPH-00689
Species: E. coli
Expression System: E. coli
GlpD Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00575
Species: E. coli
Expression System: E. coli
HSD11B2 Protein, Human, Recombinant (His)
Cat.No: TMPH-00844
Species: Human
Expression System: P. pastoris (Yeast)
MDH1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00955
Species: Human
Expression System: E. coli
MGAT1 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03198
Species: Rabbit
Expression System: E. coli
OGDC-E2 Protein, E. coli O157:H7, Recombinant (His)
Cat.No: TMPH-00667
Species: E. coli
Expression System: E. coli
Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03260
Species: Rat
Expression System: E. coli
Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02644
Species: Mouse
Expression System: E. coli
HMGCR Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02476
Species: Mouse
Expression System: E. coli
KHK Protein, Human, Recombinant (His)
Cat.No: TMPJ-00479
Species: Human
Expression System: HEK293 Cells
TGS1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02246
Species: Human
Expression System: E. coli
PGDS Protein, Human, Recombinant
Cat.No: TMPJ-00690
Species: Human
Expression System: E. coli
PMVK Protein, Human, Recombinant (His)
Cat.No: TMPY-04767
Species: Human
Expression System: E. coli
MGAT2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01092
Species: Human
Expression System: HEK293 Cells
GMPR Protein, Human, Recombinant (His)
Cat.No: TMPY-03617
Species: Human
Expression System: E. coli
AICDA Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02908
Species: Mouse
Expression System: E. coli
GPC1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01368
Species: Mouse
Expression System: HEK293 Cells
MTHFS Protein, Human, Recombinant (His)
Cat.No: TMPJ-00989
Species: Human
Expression System: E. coli
LDHA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00724
Species: Human
Expression System: E. coli
CKM Protein, Human, Recombinant (His)
Cat.No: TMPY-04762
Species: Human
Expression System: E. coli
UROD Protein, Human, Recombinant (His)
Cat.No: TMPJ-00788
Species: Human
Expression System: E. coli
GPI Protein, Human, Recombinant (His)
Cat.No: TMPH-01391
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0127 Diclofenac-d4

Diclofenac-d4 是 Diclofenac 的氘代化合物。Diclofenac 的 CAS 号为 15307-86-5。Diclofenac 是一种具有抗炎活性的非甾体苯乙酸衍生物,是COX抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的IC50值分别为 5.1 μM,0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。
TMIJ-0519 Fosaprepitant-d4 Dimeglumine

Fosaprepitant-d4 Dimeglumine 是 Fosaprepitant Dimeglumine 的氘代化合物。Fosaprepitant Dimeglumine 的 CAS 号为 265121-04-8。Fosaprepitant dimeglumine 是 Aprepitant 的前药。它是一种神经激肽 1 受体拮抗剂,可用于预防化疗引起的恶心呕吐。
TMID-0178 Stearic acid-18,18,18-d3

Stearic acid-18,18,18-d3 是 Stearic acid 的氘代化合物。Stearic acid 的 CAS 号为 57-11-4。Stearic acid是长链饱和脂肪酸,存在于许多动植物油脂中。
TMID-0233 Salbutamol-d9

Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
TMIH-0512 Salbutamol-d3

Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。

同位素标记化合物

Diclofenac-d4
Cat.No: TMIJ-0127
Synonym:
Target:
Fosaprepitant-d4 Dimeglumine
Cat.No: TMIJ-0519
Synonym:
Target:
Stearic acid-18,18,18-d3
Cat.No: TMID-0178
Synonym:
Target:
Salbutamol-d9
Cat.No: TMID-0233
Synonym:
Target:
Salbutamol-d3
Cat.No: TMIH-0512
Synonym:
Target:
TargetMol Loading
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