313
149
4
380
9
Cat. No. | Product Name | ||
---|---|---|---|
L6750 | 活血化瘀中药单体库 | 580 compounds | |
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。 | |||
L1300 | PI3K/Akt/mTOR 化合物库 | 420 compounds | |
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选; | |||
L6730 | 抗病毒中药单体化合物库 | 268 compounds | |
268 种具有抗病毒活性的中药单体集合,是药物开发、药理研究的有效工具; | |||
L6720 | 抗COVID-19中药单体库 | 1147 compounds | |
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1147 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19995 |
C.I. Azoic Coupling Component 5
NSC 37212,NSC37212,Cibanaphthol AG,Diacetylacetotolidide,Daito Grounder G,NSC-37212 |
||
C.I. Azoic Coupling Component 5 is an indicator of fluorescent. | |||
T19996 |
C.I. 37550
Acna Naphthol SS,C.I. Azoic Coupling Component 12,Azoground ITR,Amanil Naphthol AS-ITR,Azotol O,Daito Grounder ITR |
||
C.I. 37550 is an indicator of fluorescent. | |||
T8365 |
Methenamine Hippurate
|
Antibacterial | Microbiology/Virology |
Methenamine hippurate 是一种口服活性尿液广谱抗菌剂。它对大多数常见的尿路病原体有效。 | |||
T6819 |
Desogestrel
Org-2969,去氧孕烯,Desogen,Desogestrelum,Cerazette |
Estrogen/progestogen Receptor; Progesterone Receptor | Endocrinology/Hormones; Others |
Desogestrel (Cerazette) 是第三代孕激素类似物,存在于许多口服避孕制剂中。 | |||
T15140 |
DLinDMA
|
Others | Others |
DLinDMA 是一种稳定的核酸脂质颗粒 (SNALPs) 中的关键脂质成分,是一种可电离的阳离子脂质。它可用于siRNA 递送的研究。 | |||
T21808 |
Inotilone
|
Others | Others |
Inotilone 是中药材 Inonotus linteus 的主要成分,可用于转移性肺癌细胞的研究。 | |||
T40645 |
PIPES
1,4-Piperazinediethanesulfonic acid,1,4-piperazine bis(ethanesulfonic acid),1,4-Piperazinebis(ethanesulfonic acid),PIPES |
Others | Others |
PIPES (1,4-Piperazinediethanesulfonic acid) 作为PIPES缓冲液的关键成分,广泛应用于生化领域作为试剂。 | |||
T38845 |
Dodecamethylpentasiloxane
|
Parasite | Microbiology/Virology |
Dodecamethylpentasiloxane 可用作臭虫杀虫剂。 Dodecamethylpentasiloxane 是硅氧烷的一种成分,可用作硅油。 | |||
T4574 |
Sacubitril
AHU 377,AHU377,沙库必曲,AHU-377 |
Neprilysin | Metabolism |
Sacubitril (AHU-377) 是一种有效的NEP 抑制剂,IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。 | |||
T6105 |
Phosphorylcholine chloride
phosphorylcholine,磷酸胆碱,Phosphocholine chloride |
Others | Others |
Phosphorylcholine chloride 是一种构成细胞膜外层结构卵磷脂的组分,血液相容性较好。 | |||
T0497 |
Cetrimonium bromide
Lauroseptol,Cetyltrimethylammonium Bromide,西曲溴铵,CTAB |
Antibiotic | Microbiology/Virology |
Cetrimonium bromide (Lauroseptol) 是局部消毒剂 Cetrimide 的组成部分之一,是一种阳离子季胺盐表面活性剂。 | |||
T85315 |
cis-8-Dodecen-1-ol
|
||
cis-8-Dodecen-1-ol 是一种 Grapholita molesta 引诱剂,是一种雌性 Grapholita molesta 的性信息素成分,常用农业。 | |||
T22374 |
N-(beta-Ketocaproyl)-L-hoMoserine lactone
N-3-氧-己酰高丝氨酸内酯,N-(β-Ketocaproyl)-L-hoMoserine lactone,N-(Ketocaproyl)-L-homoserine lactone,N-(β-Ketocaproyl)-L-hoMoserine lactone |
Others | Others |
N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) 是群体调节感应的成分之一。 | |||
T2199 |
Myclobutanil
Systhane,腈菌唑 |
Antifungal | Microbiology/Virology |
Myclobutanil (Systhane) 是康唑类抗真菌剂,可用作农药。 | |||
T5116 |
Iprodione
|
Others; Reactive Oxygen Species; Antifungal | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others |
Iprodione 是一种二甲酰亚胺类的高度特异性杀菌剂,能通过产生自由氧自由基引起氧化损伤。 | |||
T0352 |
Dibenzothiophene
二苯并噻吩,Imino semicarbazide,Diphenylene sulfide |
Others | Others |
Dibenzothiophene (Imino semicarbazide) 是有机合成过程的中间体,是由两个苯环稠合到一个中心的噻吩环。 | |||
T21727 |
Ivermectin B1a
|
SARS-CoV; Parasite | Microbiology/Virology |
Ivermectin B1a 是 Avermectin B1a 的一种衍生物,是 Ivermectin 的主要成分。Ivermectin 是广谱的抗寄生虫剂。Ivermectin 也是抗 SARS-CoV-2/COVID-19 的候选药物。 | |||
T11244 |
Etimizol
Ethymisol,Ethimizole,Ethymisole |
Others | Others |
Etimizol (Ethimizole) 对缺氧造成的失忆症有效果。 | |||
T10863 |
Complement C5-IN-1
|
Complement System | Immunology/Inflammation |
Complement C5-IN-1 (Compound 7) 是补体成分蛋白5 (C5) 的小分子抑制剂。 Complement C5-IN-1 与 C5 相互作用以防止其被 C5 转化酶切割, 阻断酵母多糖诱导的 50%人全血 MAC 沉积的 IC50 值为 0.77 μM。 | |||
T4544 |
Elbasvir
MK-8742 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Elbasvir (MK-8742) 是丙型肝炎病毒的非结构蛋白 5A 抑制剂,可用于治疗慢性 HCV 感染。 | |||
T5821 |
BC-1215
|
Others; Ligand for E3 Ligase | Others; PROTAC |
BC-1215 是一种 F-box protein 3 抑制剂。它能够稳定 TRAF1-TRAF6 来抑制 Fbxo3-TRAF 激活途径。它与 ApaG 相互作用,阻碍来自人 PBMC 广谱 TH1 细胞因子的分泌。 | |||
T0412 |
Idebenone
艾地苯醌,CV-2619 |
Apoptosis; Antioxidant; Mitochondrial Metabolism | Apoptosis; Metabolism; oxidation-reduction |
Idebenone (CV-2619) 是一种线粒体保护剂,具有神经保护功效,可用于研究阿尔茨海默病、亨廷顿舞蹈病,可透过血脑屏障,诱导细胞凋亡。 | |||
T37735 |
Stearoyl-L-carnitine chloride
C18 Carnitine,Stearoylcarnitine chloride |
||
Stearoyl-L-carnitine chloride(Acylcarnitine C18:0) 是一种存在于小脑中的长链酰基肉碱,抑制 GlyT2 ,是研究脂代谢的重要组成部分。 | |||
T18540 |
Phe-Lys(Trt)-PAB
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Phe-Lys(Trt)-PAB 是一种组织蛋白酶可裂解的 ADC 接头,用于合成抗体-药物偶联物。 | |||
T6715 |
Valnemulin hydrochloride
盐酸沃尼妙林,Valnemulin HCl |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Valnemulin hydrochloride (Valnemulin HCl) 是截短侧耳素抗生素,与 50s 核糖体亚基中的肽基转移酶结合来抑制细菌中的蛋白质合成。 | |||
T67905 |
GS-829845
|
JAK; Drug Metabolite | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Metabolism; Stem Cells |
GS-829845 是一种 JAK1 抑制剂,是 Filgotinib 活性代谢物的主要成分,其效力比母体低约 10 倍且半衰期更长。 | |||
T61194 |
D75-4590
|
Others | Others |
D75-4590是一种β-1,6-葡聚糖抑制剂。由于葡聚糖是细胞壁的主要成分,特别是β-1,6-葡聚糖,D75-4590可以通过抑制其合成酶来对抗真菌感染。 | |||
TP1299 |
Melittin
蜂毒素,蜂毒肽 |
Phospholipase | Metabolism |
Melittin 是 PLA2激活剂,能够刺激低分子量 PLA2的活性,而不刺激高分子量 PLA2的活性。 | |||
TP1880L1 |
PAMP-12 (human, porcine) acetate
PAMP-12 (human, porcine) acetate(196305-05-2 free base) |
Others | Others |
PAMP-12 (human, porcine) acetate (PAMP-12 (human, porcine) acetate (196305-05-2 free base)) 是 ir-PAMP 的主要成分,由 AM 前体加工而成,PAMP-20 也是如此,并且可能参与心血管控制。 | |||
T6386 |
Ampicillin sodium
氨苄西林钠,Domicillin,D-(-)-α-Aminobenzylpenicillin sodium salt,Penialmen,Citteral |
Antibacterial; Antibiotic | Microbiology/Virology |
Ampicillin sodium (Domicillin) 是Ampicillin 的钠盐形式,是Ampicillin 的广谱半合成衍生物。它通过与青霉素结合蛋白结合来抑制细菌细胞壁的合成,从而抑制肽聚糖的合成,肽聚糖是细菌细胞壁的关键成分。 | |||
T35363 |
HM-cytosine
5hmC,5-Hydroxymethylcytosine,5-羟甲基胞嘧啶 |
Others | Others |
HM-cytosine (5hmC) (5hmC) 是哺乳动物基因组 DNA 中天然存在的成分,被认为是 DNA 的第六个碱基。HM-cytosine 是活性 DNA 去甲基化的中间代谢物。HM-cytosine 是已知会影响哺乳动物全局基因表达的表观遗传标记。 | |||
T2305 |
Isavuconazole
艾沙康唑,BAL-4815,RO-0094815 |
P450; Antibiotic; Antifungal | Metabolism; Microbiology/Virology |
Isavuconazole (RO-0094815) 是一种三唑类前药,对酵母、霉菌和二型真菌具有抗真菌活性。它抑制麦角固醇生物合成,导致真菌膜结构和功能的破坏。它是 CYP3A4抑制剂。 | |||
T40870 |
Leukotriene E4
LTE4 |
Endogenous Metabolite | Metabolism |
Leukotriene E4 (LTE4)(LTE4)通过 二肽酶对LTD4 上的作用生成,是过敏性休克慢反应物质(SRS-A)的成分之一。LTE4 存在于血浆和尿液中,可用于检测哮喘。 | |||
T36310 |
AKT-IN-6
INCB-047775 |
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
AKT-IN-6 (INCB-047775)对ATK 有抑制作用。Akt 是对生长因子、细胞因子和其他细胞刺激的细胞信号传导的重要组成部分。Akt 的异常激活与2型糖尿病和癌症的发生密切相关。 | |||
TP2137L |
pp60 c-src (521-533) (phosphorylated) acetate
|
Others | Others |
pp60 c-src (521-533) (phosphorylated) acetate 是粘着斑形成和细胞扩散的调节剂。它还调节细胞运动,是由促运动透明质酸受体 RHAMM 触发的信号通路中的关键成分。 | |||
T30251 |
AZD-1305
UNII-CZO834LXQM,AZD 1305 |
Others | Others |
AZD-1305是一种新型抗心律失常化合物,主要阻断哺乳动物细胞和心室心肌细胞中 IKr 的快速组分、l 型钙电流和病房内钠电流,可用于研究逆转心律失常。 | |||
T5022 |
Ceforanide
|
Antibacterial; Antibiotic | Microbiology/Virology |
Ceforanide 是一种头孢菌素,可静脉或肌肉给药。它在体外具有一系列抗菌活性。 | |||
T13392 |
ZEN-3219
|
Others; Epigenetic Reader Domain | Chromatin/Epigenetic; Others |
ZEN-3219 是一种 BET 抑制剂,对 BRD4(BD1),BRD4(BD2) 和 BRD4(BD1BD2)既有抑制作用,ZEN-3219对 BRD4(BD1),BRD4(BD2) 和 BRD4(BD1BD2)的 IC50 分别为 0.48, 0.16 和 0.47 μM。ZEN-3219 是 PROTAC 分子的组成部分,可诱导 BRD4 降解。。 | |||
TP1299L |
Melittin TFA(20449-79-0(free base))
|
Phospholipase | Metabolism |
Melittin TFA(20449-79-0(free base)) 是一种含有 26 个氨基酸残基的小蛋白质,是蜂毒的主要毒性成分。它是一种 PLA2 活化剂,可刺激低分子量 PLA2 的活性,而不会增加高分子量 PLA2 的活性。 | |||
T9928 |
Ranibizumab
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Ranibizumab 是一种人源化单克隆抗体片段,旨在靶向和抑制血管内皮生长因子 (VEGF),包括 VEGF110、VEGF121 和 VEGF165。 Ranibizumab 选择性靶向和中和 VEGF-A 同工型的能力使其成为湿性年龄相关性黄斑变性 (AMD) 研究和治疗策略的重要组成部分。 | |||
T6476 |
Dofetilide
UK 68789,UK-68798,Tikosyn,多非利特 |
Potassium Channel | Membrane transporter/Ion channel |
Dofetilide (UK 68789) 是一种具有口服活性、有效的且特异性的IKr 阻滞剂,作为 III 类抗心律失常药物。Dofetilide 可用于心血管疾病研究。 | |||
T33631 |
Neocuproine
Neocuproin |
Others | Others |
Neocuproine 是一种铜 (I) 螯合剂,可增强电场刺激引起的输精管收缩的嘌呤能成分,常被用作配位试剂和铜离子检测剂。Neocuproine 与铜离子形成稳定的络合物,并可在某些化学反应和分析方法中起到催化作用。Neocuproine 作为铁和钴上的氧化还原活性配体平台,对NSC34细胞氧化损伤的保护作用。 | |||
T1224 |
Cefuroxime sodium
Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素,增加了对 β-内酰胺酶的稳定性。 | |||
T1187 |
Bifonazole
联苯苄唑,Bay H-4502 |
P450; Antibiotic; Antifungal | Metabolism; Microbiology/Virology |
Bifonazole (Bay H-4502) 是咪唑类抗真菌剂。 | |||
T1290 |
Oxiconazole nitrate
硝酸奥昔康唑,Ro 13-8996 |
Others; Antibiotic; Antifection; Antifungal | Microbiology/Virology; Others |
Oxiconazole nitrate (Ro 13-8996) 是广谱抗真菌药物,抑制T. tonsurans 和T.rubrum 的生长,MIC90值分别为 0.25 和 0.5 μg/mL。 | |||
TP1238L |
ACTH 1-14 acetate(25696-21-3 free base)
Adrenocorticotropic Hormone Fragment 1-14 acetate |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
ACTH 1-14 acetate(25696-21-3 free base) (Adrenocorticotropic Hormone Fragment 1-14 acetate) 是促肾上腺皮质激素的片段,可调节皮质醇和雄激素的产生。促肾上腺皮质激素 (ACTH),也称为促肾上腺皮质激素,由垂体前叶产生和分泌。作为对生物应激的反应,ACTH 是下丘脑-垂体-肾上腺轴的重要组成部分。 | |||
T6686 |
Sulconazole mononitrate
Exelderm,Sulconazole Nitrate,RS 44872,硝酸硫康唑 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Sulconazole mononitrate (Exelderm) 是一种咪唑类广谱杀菌剂。它可研究皮肤真菌病,花斑糠疹病,皮肤念珠菌病。 | |||
T4200 |
Sacubitril hemicalcium salt
AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt |
Neprilysin | Metabolism |
Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂,IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。 | |||
T3934 |
Isavuconazonium sulfate
|
Antifungal | Microbiology/Virology |
Isavuconazonium sulfate 是一种口服活性抗真菌药,是活性三唑类抗真菌药物 Isavuconazole 的前药,可用于侵袭性曲霉菌病和毛霉菌病。 | |||
T8902 |
DOTMA
Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium |
Others | Others |
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) 作为 tetra-methylated DOTA 类似物,是一种阳离子脂类,被用作基因治疗的非病毒载体。它已被用作脂质体的成分,可用于封装 siRNA、microRNA 和寡核苷酸,并用于体外基因转染。在体外和体内均表现出良好的基因转染效果。DOTMA 诱导脂质体上的正电荷,从而促进脂质体与细胞膜的有效相互作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22221 |
2-Undecanol
2-十一醇,2-Hendecanol,Methyl nonyl carbinol,Undecan-2-ol,2-Hydroxyundecane |
Others | Others |
2-Undecanol (Methyl nonyl carbinol) 是一种从树液甲虫 Lobiopa insularis 中鉴定出的特定挥发物。它是一种花朵释放的挥发物,是膜翅目昆虫的各种物种用作信息素成分之一。 | |||
TN6753 |
1-TETRACOSANOL
二十四醇,Tetracosanol,LIGNOCERYL ALCOHOL |
Others | Others |
1-Tetracosanol (LIGNOCERYL ALCOHOL) 是从多根火龙果 Hylocereus polyrhizus 中提取的天然成分。 | |||
TN6700 |
gamma-Nonanolactone
|
Others | Others |
gamma-Nonanolactone 是蒸小麦的香气成分。 | |||
TN1127 |
Salviaflaside
|
Antioxidant | oxidation-reduction |
Salviaflaside 是夏枯草的主要生物活性成分,具有抗氧化活性。 | |||
T0543 |
7-Methylxanthine
Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤 |
Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Adenosine Receptor | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience |
7-Methylxanthine 是一种黄嘌呤的甲基衍生物,是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。 | |||
TN2341 |
Cucurbitacin Q1
葫芦素F-25-乙酸酯,葫芦素Q1 |
Others | Others |
Cucurbitacin Q1 是一种天然的四环三萜,来源于Cucumis prophetarum。 | |||
T11047 |
DiosMetin 7-O-β-D-Glucuronide
|
Others; Antioxidant | Others; oxidation-reduction |
DiosMetin 7-O-β-D-Glucuronide 是一种丝瓜中的抗氧化成分。 | |||
T2977 |
Vanillin acetate
Acetovanillin,乙酰香兰酯,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,乙酰香兰素,4-Acetoxy-3-methoxybenzaldehyde |
Others | Others |
Acetylvanillin 可由香草醛用乙酸酐处理后得到。 | |||
TN2033 |
Padmatin
李属素,Blumeatin C |
Others | Others |
Padmatin (Blumeatin C) 是一种从 Prunus puddum 中分离出来的二氢黄酮醇。 | |||
TN1384 |
Angelicain
当归碱,去甲升麻素,Norcimifugin |
Others | Others |
Angelicain (Norcimifugin) 是升麻 (Cimicifuga foetida) 的一种具有抗炎作用的成分。 | |||
TN6890 |
Methyl octanoate
Methyl n-Octanoate,辛酸甲酯 |
Others | Others |
Methyl octanoate (Methyl n-Octanoate) 是一种具有挥发性的化合物,也是柿子酒的香气成分。 | |||
T19295 |
Docosapentaenoic acid 22n-3
|
Endogenous Metabolite | Metabolism |
Docosapentaenoic acid 22n-3 是在所有动物细胞膜中发现的磷脂组成成分。 | |||
T5S1569 |
AKBA
乙酰基-11-酮基-beta-乳香酸,3-O-Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-beta-boswellic acid,Acetyl-11-keto-β-boswellic acid |
Others; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite | Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; Others |
AKBA (3-O-Acetyl-11-keto-beta-boswellic acid) 是一种从乳香中分离的天然成分,是新颖的 Nrf2 的活化剂。 | |||
TN6747 |
Phenyl-β-D-glucopyranoside
苯基-BETA-葡萄糖吡喃糖苷,PHENYL-B-D-GLUCOPYRANOSIDE |
Others | Others |
Phenyl-β-D-glucopyranoside (PHENYL-B-D-GLUCOPYRANOSIDE) 是黄柏的一种成分,具有抗癌和抗炎活性。 | |||
T6S1500 |
Ginsenoside Rf
人参皂苷 Rf,Ginsenoside-Rf,Panaxoside Rf |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
Ginsenoside Rf (Panaxoside Rf) 是人参根的微量成分,可抑制 N 型 Ca2+通道。 | |||
T41288 |
Myristoleic acid
cis-9-tetradecenoic acid,肉豆蔻酸,9-Tetradecenoic acid,(Z)-Tetradec-9-enoic acid |
Apoptosis | Apoptosis |
Myristoleic acid (9-Tetradecenoic acid) 是 Serenoa repens 提取物中的一种细胞毒性成分。Myristoleic acid 诱导人前列腺 LNCaP 细胞凋亡和坏死。 | |||
T19606 |
Xylan
|
Others | Others |
Xylan 是开花植物的次生植物细胞壁中的半纤维素成分,是一种由木糖单元组成的多糖,主要包含由纤维素连接的 β-D-木糖单位。 | |||
T2793 |
Tetrahydropalmatine
DL-Tetrahydropalmatine,四氢帕马丁,延胡索乙素,Rotundine |
Apoptosis; Others; Dopamine Receptor | Apoptosis; GPCR/G Protein; Neuroscience; Others |
Tetrahydropalmatine (DL-Tetrahydropalmatine) 通过抑制大鼠杏仁核的多巴胺释放来抑制癫痫发作,用于缓解疼痛的研究。 | |||
T8165 |
Erythrodiol
|
Endogenous Metabolite; ABC | Membrane transporter/Ion channel; Metabolism |
Erythrodiol 是一种橄榄油的成分,能够选择性抑制ABCA1蛋白的降解来促进胆固醇外流,有用于动脉粥样硬化的研究潜力。 | |||
T1424 |
Ethynyl estradiol
乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Ethynyl estradio 是一种高效的生物活性雌激素。 | |||
TMA1603 |
Parishin C
巴利森苷 C,巴利森苷C |
Antioxidant | oxidation-reduction |
Parishin C 是一种从天麻中分离出的 Parishin 衍生物,可能具有抗氧化作用。 | |||
T3251 |
Stachydrine Hydrochloride
|
NF-κB | NF-κB |
Stachydrine hydrochloride 是Herba Leonuri 的主要活性成分,可以抑制NF-κB 信号通路。它可用于心血管疾病的研究,具有抗心肌肥大活性 。 | |||
T0136 |
Citicoline
CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline |
Apoptosis; Dopamine Receptor; Endogenous Metabolite | Apoptosis; GPCR/G Protein; Metabolism; Neuroscience |
Citicoline (CDP-Choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体,有神经保护作用。 | |||
T5430 |
[8]-Shogaol
8-SHOGAOL,8-姜烯酚 |
Apoptosis; COX | Apoptosis; Immunology/Inflammation; Neuroscience |
[8]-Shogaol 是生姜中的一种刺激性酚类天然产物,可诱导人白血病细胞凋亡,抑制 COX-2的IC50为17.5 μM,具有抗血小板活性,IC50为5 μM。 | |||
T13616 |
cis-9,10-Epoxystearic acid
cis-9,10-Epoxystearic acid,cis-9,10-Epoxyoctadecanoic acid |
Endogenous Metabolite | Metabolism |
cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) 是来自人血液和尿液的内源性成分。它可以通过油酸和非酶环氧化反应从油酸中制备。 | |||
T22293 |
Chondroitine sulfate
Chondroitine sulfate (From cattle) |
Others | Others |
Chondroitine sulfate 是软骨的重要结构成分,已被用作治疗关节不适的膳食补充剂。 | |||
T7035 |
ANTHRAQUINONE-2-CARBOXYLIC ACID
|
IRAK; Syk | Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors |
Anthraquinone-2-carboxylic acid 从 Brazilian taheebo 中分离得到,具有抗炎、缓解疼痛的作用。 | |||
TN1499 |
Cimiracemoside C
千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Cimicifugoside M |
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Cimiracemoside C (Cimicifugoside M) 是在升麻中发现的一种天然产物,可激活 AMPK 并具有抗糖尿病的潜在活性。 | |||
TN6822 |
3,5-Dimethoxytoluene
Orcinol dimethyl ether,1,3-dimethoxy-5-methylbenzene |
Others | Others |
3,5-Dimethoxytoluene (Orcinol dimethyl ether) 是玫瑰中主要香味成分,具有镇静作用,可作为一种害虫引诱剂使用。 | |||
T3S1541 |
(Iso) (-)-Zuonin A
rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m,(7S,7'R)-双(3,4-亚甲二氧苯基)-rel-(8R,8'R)-二甲基四氢呋喃 |
Others | Others |
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan 为肉豆蔻果实中发现的化学成分。 | |||
T3396 |
Baohuoside I
Icariside-II,宝藿苷I,Icariin-II,宝藿苷 I |
Apoptosis; CXCR | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation |
Baohuoside I (Icariside-II) 是从朝鲜淫羊藿中得到的一种黄酮类天然产物,是CXCR4抑制剂,抑制 CXCR4 的表达,诱导凋亡,具有抗肿瘤活性。 | |||
T0434 |
D-Glucuronic acid lactone
Glucuronolactone,D-Glucurone,Dicurone,葡醛内酯 |
Others; Endogenous Metabolite | Metabolism; Others |
D-Glucuronic acid lactone (Dicurone) 是内源性代谢产物的一种。 | |||
T3344 |
Ciwujianoside B
yemuoside YM,刺五加皂苷 B,acanthopanax senticosides B,刺五加皂甙 B,Ciwujianoside-B |
BCL; Others | Apoptosis; Others |
Ciwujianoside B (acanthopanax senticosides B) 是刺五加的主要成分,能缓解疲劳,增强记忆力,提高人的认知能力。 | |||
TQ0240 |
6"-O-Apiosyl-5-O-Methylvisammioside
|
Others | Others |
6”-O-Apiosyl-5-O-Methylvisammioside 是中药颈复康的成分之一,颈复康具有活血通络,散风止痛的作用。 | |||
T0036 |
18β-Glycyrrhetinic acid
Enoxolone,甘草次酸,18β-甘草次酸,Glycyrrhetin |
Dehydrogenase; Endogenous Metabolite | Metabolism |
18β-Glycyrrhetinic acid (Enoxolone) 是甘草的主要生物活性成分,具有抗炎,抗增殖和抗溃疡的特性。 | |||
T3090 |
Abietic Acid
Rosin Acid,L-Abietic acid,Sylvic acid,松香酸,Abietate |
MMP; Lipoxygenase; Antibacterial; PPAR | DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Proteases/Proteasome |
Abietic Acid (Sylvic acid) 是从 Pimenta racemosavar. grissea 中提取出来的一种二萜,具有抗菌、抗增殖和抗肥胖的活性。它抑制脂氧合酶活性,可研究过敏性疾病。 | |||
TN1056 |
Mogroside IIe
|
IL Receptor | Immunology/Inflammation |
Mogroside IIe 是一种天然来源的三萜糖苷,作为非糖类甜味剂,Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。 | |||
TN1096 |
Ginsenoside Ra1
人参皂苷 Ra1,人参皂苷Ra1 |
Others; Tyrosine Kinases | Others; Tyrosine Kinase/Adaptors |
Ginsenoside Ra1 是来自人参的成分。 Ginsenoside Ra1 对缺氧/复氧诱导的蛋白酪氨酸激酶 (PTK) 活化具有显着抑制作用。 | |||
T2945 |
Germacrone
|
P450; Antiviral; Influenza Virus | Immunology/Inflammation; Metabolism; Microbiology/Virology |
Germacrone 提取自姜黄,具有抗炎、抗雄激素和抗病毒活性。 它还通过促进细胞凋亡来抑制胶质瘤细胞的增殖。 | |||
TN6961 |
Heneicosane
N-HENEICOSANE,正二十一烷,henicosane |
Antifungal | Microbiology/Virology |
Heneicosane (henicosane) 是一种信息素,是从 Streptomyces philanthiRL-1-178 或 Serapias cordigera 中分离出来的一种香气成分,可抑制黄曲霉毒素的产生。 | |||
TN7117 |
regaloside I
|
Others | Others |
Regaloside I 是百合中的单体成分,可能是保护人类皮肤成纤维细胞免受 UVA 诱导的形态变化的主要成分。 | |||
T4955 |
saponaretin
Isovitexin,Apigenin-6-C-glucoside,异牧荆素 |
Apoptosis; Antioxidant | Apoptosis; oxidation-reduction |
saponaretin 是许多中药的活性成分,具有多种活性,如抗氧化、抗炎、抗阿尔茨海默病(AD)作用等。 | |||
T2P2937 |
Nonacosane
|
Others; Antibacterial | Microbiology/Virology; Others |
Nonacosane 是从Baphia massaiensis 分离的,是一种由 29 个碳原子组成的直链烷烃,具有植物代谢物和挥发油成分的作用。 | |||
T22327 |
Ethanolamine hydrochloride
甲基氧氯酸,2-Aminoethanol hydrochloride,乙醇胺盐酸盐 |
Others | Others |
Ethanolamine hydrochloride (2-Aminoethanol hydrochloride) 是一种具有氨气味的粘性、吸湿性氨基醇,广泛分布于生物组织中,是卵磷脂的一种成分。 | |||
T3O2784 |
Vitamin B6
维生素B6 |
Others | Others |
Vitamin B6 是人体某些辅酶的成分,参与多种代谢反应,特别是与氨基酸代谢有关。维生素B6在防治妊娠和放射病呕吐中的临床应用。 | |||
T8301 |
Amaranth
Acid Red 27,酸性红 27 |
Others | Others |
Amaranth (Acid Red 27) 是一种阴离子染料, 可应用到天然和合成纤维、皮革、纸张及苯酚-甲醛树脂。它是一种暗红色至紫色的偶氮染料,可用作食品染料和化妆品。 | |||
T2926 |
Schizandrin A
|
P450; Virus Protease; Autophagy | Autophagy; Metabolism; Microbiology/Virology |
Schisandrin A 是一种从东方药物五味子中提取的主要有效成分,抑制 CYP3A 活性,IC50 分别为 6.60 μM 和 Ki 为 5.83 μM。 | |||
T0539 |
Dihydrocaffeic acid
二氢咖啡酸,Hydrocaffeic acid |
Antioxidant; p38 MAPK; Endogenous Metabolite | MAPK; Metabolism; oxidation-reduction |
Dihydrocaffeic acid 是绿原酸的代谢物,是一种众所周知的抗氧化成分,具有抗氧化、抗阿尔茨海默病、神经保护、唤醒和降脂作用。 | |||
T3387 |
Phytolaccagenin
|
Others; Antibacterial | Microbiology/Virology; Others |
Phytolaccagenin 是一种三萜类皂苷,是商陆的活性成分,有抗真菌活性,抗炎活性和较低的毒性。在东亚国家广泛用于治疗炎症相关疾病。 | |||
T3025 |
Asiaticoside
BRN0078195,CCRIS8995,Emdecassol,Ba 2742,Madecassol,积雪草皂苷,NSC166062,积雪草苷 |
Apoptosis; p38 MAPK; Reactive Oxygen Species; Endogenous Metabolite; TGF-beta/Smad | Apoptosis; Immunology/Inflammation; MAPK; Metabolism; NF-κB; Stem Cells |
Asiaticoside (Emdecassol) 是一种从积雪草中分离得到的三萜皂苷化合物,具有抗氧化、抗炎、抗溃疡等作用。在瘢痕疙瘩成纤维细胞中,它通过活化 Smad7,抑制 TGF-βRI 和 TGF-βRII,抑制 TGF-β/Smad 信号通路。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05732 |
Complement C3 Protein, Cynomolgus, Recombinant (His)
complement component 3 |
Cynomolgus | HEK293 Cells |
Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.40 kDa and the accession number is XP_005587776.1. | |||
TMPY-00686 |
Complement C2 Protein, Human, Recombinant (His)
CO2,complement component 2,ARMD14 |
Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1. | |||
TMPY-03195 |
Serum Amyloid P Protein, Human, Recombinant (His)
amyloid P component, serum,HEL-S-92n,SAP,PTX2 |
Human | HEK293 Cells |
Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743. | |||
TMPY-05325 |
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His)
exosome component 9,p5,p6,PMSCL1,Rrp45p,RRP45,PM/Sc... |
Human | Baculovirus Insect Cells |
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.3 kDa and the accession number is Q06265-1. | |||
TMPY-05057 |
Complement C5 Protein, Human, Recombinant (His & FLAG)
C5b,ECLZB,C5a,CPAMD4,C5D,complement component 5,Com... |
Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 188.8 kDa and the accession number is P01031. | |||
TMPY-00653 |
Complement C5 Protein, Human, Recombinant (Complement C5a)
C5D,C5b,CPAMD4,complement component 5,Complement C5... |
Human | E. coli |
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is P01031. | |||
TMPY-01186 |
Argonaute-2 Protein, Human, Recombinant (His)
EIF2C2,argonaute RISC catalytic component 2,Argonau... |
Human | Baculovirus Insect Cells |
Argonaute-2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 99 kDa and the accession number is Q9UKV8. | |||
TMPY-05731 |
Complement C3 Protein, Human, Recombinant (His)
HEL-S-62p,CPAMD1,ARMD9,C3b,ASP,C3a,AHUS5,complement comp... |
Human | HEK293 Cells |
Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024. | |||
TMPY-02130 |
Argonaute-2 Protein, Mouse, Recombinant (His)
mKIAA4215,1110029L17Rik,2310051F07Rik,Ago2,argonaute RISC ca... |
Mouse | Baculovirus Insect Cells |
Argonaute-2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 99 kDa and the accession number is Q8CJG0. | |||
TMPY-06538 |
Complement C5 Protein, Cynomolgus, Recombinant
complement component 5 |
Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.41 kDa and the accession number is XP_005580972.1. | |||
TMPY-03447 |
Complement C2 Protein, Mouse, Recombinant (His)
complement component 2 |
Mouse | HEK293 Cells |
Complement C2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is P21180-1. | |||
TMPY-06137 |
Complement C5 Protein, Cynomolgus, Recombinant (His)
complement component 5 |
Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 188.1 kDa and the accession number is XP_005580972.1. | |||
TMPY-02641 |
Complement C6 Protein, Human, Recombinant (His)
complement component 6 |
Human | HEK293 Cells |
Complement C6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104 kDa and the accession number is AAA59668.1. | |||
TMPY-05459 |
Complement C5a Protein, Mouse, Recombinant, Biotinylated
complement component 5 |
Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPY-04902 |
Complement C5a Protein, Mouse, Recombinant
complement component 5 |
Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPY-02370 |
Serum Amyloid P Protein, Rat, Recombinant (His)
amyloid P component, serum |
Rat | HEK293 Cells |
Serum Amyloid P Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P23680. | |||
TMPJ-00417 |
Complement C3a Protein, Human, Recombinant
Anaphylatoxin,C3a,Complement Component C3a |
Human | E. coli |
Complement C3a Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 KDa and the accession number is P01024. | |||
TMPY-02892 |
Complement C7 Protein, Human, Recombinant (His)
Complement C7,complement component 7 |
Human | HEK293 Cells |
Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 92.6 kDa and the accession number is P10643. | |||
TMPY-00666 |
Serum Amyloid P Protein, Mouse, Recombinant (His)
amyloid P component, serum,Sap |
Mouse | HEK293 Cells |
Serum Amyloid P Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P12246. | |||
TMPJ-00416 |
Complement C3a Protein, Mouse, Recombinant
C3a,Complement Component C3a,Anaphylatoxin |
Mouse | E. coli |
Complement C3a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 KDa and the accession number is P01027. | |||
TMPJ-00585 |
Complement C8 gamma Protein, Human, Recombinant (His)
C8 γ,Complement component C8 gamma chain,C8G,Comple... |
Human | E. coli |
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a... | |||
TMPY-02311 |
AGO3 Protein, Human, Recombinant (His)
EIF2C3,argonaute RISC catalytic component 3 |
Human | Baculovirus Insect Cells |
Argonaute (Ago) protein family plays a key role in the RNA interference (RNAi) process in different insects including Lepidopteran. AGO3 also coexists and interacts with Armitage in the mitochondrial fraction. Furthermore, AGO3 acts in conjunction with the mitochondria-associated protein Zucchini to control the dynamic subcellular localization of Armitage between mitochondria and nuage in a Slicer-dependent fashion. | |||
TMPY-03012 |
Complement C7 Protein, Human, Recombinant (hFc)
complement component 7,Complement C7 |
Human | HEK293 Cells |
Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 118 kDa and the accession number is P10643. | |||
TMPH-01132 |
Complement C8a Protein, Human, Recombinant (His)
C8A,Complement component 8 subunit alpha,Complement... |
Human | E. coli |
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01133 |
Complement C8b Protein, Human, Recombinant (His)
Complement component C8 beta chain,C8B,Complement <... |
Human | E. coli |
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Complement C8b Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.0 kDa and the accession number is P07358. | |||
TMPH-03556 |
HlgC Protein, S. aureus, Recombinant (E. coli, His)
hlgC,Gamma-hemolysin component C |
Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.6 kDa and the accession number is Q7A3S2. | |||
TMPJ-00683 |
SNCA Protein, Mouse, Recombinant
NACP,α-synuclein,Non-A beta component of AD amyloid... |
Mouse | E. coli |
SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042. | |||
TMPH-03557 |
HlgC Protein, S. aureus, Recombinant (His)
hlgC,Gamma-hemolysin component C |
Staphylococcus aureus | P. pastoris (Yeast) |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.6 kDa and the accession number is Q7A3S2. | |||
TMPH-00667 |
OGDC-E2 Protein, E. coli O157:H7, Recombinant (His)
Dihydrolipoamide succinyltransferase component of 2... |
E. coli | E. coli |
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). OGDC-E2 Protein, E. coli O157:H7, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P0AFG7. | |||
TMPY-00687 |
Complement C2 Protein, Human, Recombinant (hFc)
ARMD14,complement component 2,CO2 |
Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110 kDa and the accession number is P06681-1. | |||
TMPH-02626 |
DLAT Protein, Mouse, Recombinant (His)
Pyruvate dehydrogenase complex component E2,Dlat,Di... |
Mouse | HEK293 Cells |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | |||
TMPJ-00684 |
SNCA Protein, Mouse, Recombinant (His)
Snca,Non-A β component of AD amyloid,Non-A4 com... |
Mouse | E. coli |
Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Manyneurodegenerative diseases has shown that alpha-synuclein accumulates in dystrophic neurites and in Lewy bodies. The function of alpha-synuclein is closely correlated with its three-dimensional structure, especially for proteins important... | |||
TMPY-06695 |
C1QA Protein, Human, Recombinant (GST)
complement component 1, q subcomponent, A ... |
Human | E. coli |
C1QA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 50.58 kDa and the accession number is P02745. | |||
TMPH-01134 |
Complement C8g Protein, Human, Recombinant (His)
C8G,Complement component C8 gamma chain |
Human | E. coli |
C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Complement C8g Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P07360. | |||
TMPY-01712 |
C1QB Protein, Human, Recombinant (His)
complement component 1, q subcomponent, B ... |
Human | Baculovirus Insect Cells |
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Southern blot analysis of chromosomal DNA from vertebrate species demonstrated highest similarity between the C1qB genes, followed by C1qC and finally C1qA. Sequence comparison of C1... | |||
TMPH-02625 |
DLAT Protein, Mouse, Recombinant (E. coli, His)
Dihydrolipoyllysine-residue acetyltransferase component<... |
Mouse | E. coli |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. DLAT Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 62.8 kDa and the accession number is Q8BMF4. | |||
TMPY-06767 |
Complement C3 Protein, Mouse, Recombinant (His)
HSE-MSF,complement component 3,Plp,AI255234,ASP |
Mouse | HEK293 Cells |
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.34 kDa and the accession number is NP_033908.2. | |||
TMPJ-00023 |
SNCA Protein, Human, Recombinant (His)
α-Synuclein,Alpha-Synuclein,PARK1,Non-A β Component... |
Human | E. coli |
SNCA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P37840. | |||
TMPY-06585 |
C1s Protein, Human, Recombinant (His)
complement component 1, s subcomponent,C1s... |
Human | HEK293 Cells |
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex composed of the binding protein C1q and two proenzymes, C1r and C1s. Upon binding of IgG to the head of C1q, C1r undergoes autoactivation and in turn cleaves and activates C1s. C1r and C1s, the proteases responsible for activation and proteolytic activity of the C1 complex of complem... | |||
TMPY-06460 |
Alpha-Synuclein Protein, Mouse, Recombinant (His)
alphaSYN,synuclein, α (non A4 component of amyloid ... |
Mouse | E. coli |
Alpha-Synuclein Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.31 kDa and the accession number is O55042-1. | |||
TMPY-06808 |
Serum Amyloid P Protein, Human, Recombinant (hFc)
PTX2,HEL-S-92n,SAP,amyloid P component, serum |
Human | HEK293 Cells |
Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743. | |||
TMPH-02067 |
SLURP1 Protein, Human, Recombinant (His)
ARS(component B)-81/S,ARS component B,SLUR... |
Human | E. coli |
SLURP1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01992 |
PDHB Protein, Human, Recombinant (His)
Pyruvate dehydrogenase E1 component subunit beta, m... |
Human | E. coli |
PDHB Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-06814 |
Complement C5 Protein, Human, Recombinant (Flag)
C5a,CPAMD4,ECLZB,C5b,C5D,Complement C5,complement compon... |
Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 187.36 kDa and the accession number is NP_001726.2. | |||
TMPH-01316 |
ECM1 Protein, Human, Recombinant (GST & His & Myc)
Extracellular matrix protein 1,ECM1,Secretory component<... |
Human | E. coli |
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. ECM1 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q16610. | |||
TMPY-01308 |
AGO1 Protein, Human, Recombinant (His)
EIF2C,GERP95,argonaute RISC catalytic component 1,E... |
Human | Baculovirus Insect Cells |
Protein argonaute-1, also known as eukaryotic translation initiation factor 2C 1, EIF2C1, and AGO1, is a member of the argonaute family and ago subfamily. Protein argonaute-1 in humans is encoded by the EIF2C1 gene. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and argonaute 4. This genomic region is frequently lost in human cancers such as Wilms tumors, neuroblastoma, and carcinomas of the breast, liver, and colon. The human EIF... | |||
TMPJ-00759 |
VDB Protein, Human, Recombinant (His)
Group-Specific Component,DBP,VDB,GC,Gc-Globulin,Vit... |
Human | HEK293 Cells |
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on... | |||
TMPY-05545 |
DLST Protein, Human, Recombinant (His)
DLTS,dihydrolipoamide S-succinyltransferase (E2 componen... |
Human | Baculovirus Insect Cells |
DLST Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 43.9 kDa and the accession number is A0A024R6C9. | |||
TMPY-02512 |
Alpha-Synuclein Protein, Human, Recombinant
PD1,α-Synuclein,PARK4,synuclein, α (non A4 component |
Human | E. coli |
Alpha-Synuclein Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.5 kDa and the accession number is P37840-1. | |||
TMPY-06318 |
Alpha-Synuclein Protein,Human,Recombinant (H50Q)
Human α-Synuclein Protein (H50Q),synuclein, alpha (non A4 |
Human | E. coli |
Alpha-Synuclein Protein,Human,Recombinant (H50Q) is expressed in E. coli expression system. The predicted molecular weight is 14.45 kDa and the accession number is P37840-1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMID-0139 |
17α-Ethynylestradiol-2,4,16,16-d4
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17α-Ethynylestradiol-2,4,16,16-d4 是 17α-Ethynylestradiol 的氘代化合物。17α-Ethynylestradiol 的 CAS 号为 57-63-6。Ethynyl Estradiol 是一种高效的生物活性雌激素。 | |||
TMID-0065 |
Adenine-2-d1
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Adenine-2-d1 是 Adenine 的氘代化合物。Adenine 的 CAS 号为 73-24-5。Adenine 是一种嘌呤衍生物,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
TMIJ-0041 |
Hippuric Acid-d5
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Hippuric Acid-d5 是 Hippuric Acid 的氘代化合物。Hippuric Acid 的 CAS 号为 495-69-2。Hippuric Acid 是一种正常的尿液成分,是苯酸和甘氨酸结合作用下产生的一种酰基甘氨酸,来自食物的芳香化合物的代谢。 | |||
TMID-0041 |
Menaquinone-9-d7
Vitamin K2-MK9-d7 |
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Menaquinone-9-d7 是 Menaquinone-9 的氘代化合物。Menaquinone-9 的 CAS 号为 523-39-7。Menaquinone 9 (MK-9) 是一种维生素 K2 类似物,已在包括大肠杆菌在内的各种细菌中发现。Menaquinone 9 对紫外线敏感,可与细菌电子传输链的一种成分可溶性硝酸还原酶结合。 | |||
T35695 |
Oleic Acid-13C
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Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximate... | |||
TMID-0303 |
Vitamin A-d4
Retinol-d4 |
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Vitamin A-d4 是 Vitamin A 的氘代化合物。Vitamin A 的 CAS 号为 68-26-8。Retinol 及其衍生物,在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。膳食维生素 A 来源于植物中发现的多种类胡萝卜素。它富含肝脏、蛋黄和乳制品的脂肪成分。 | |||
TMIH-0025 |
13C-d3-AOH1996
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13C-d3-AOH1996 是 AOH1996 的 13C 和氘代化合物。AOH1996 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体,靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用,导致 DNA 复制应激,诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用,可抑制肿瘤细胞生长。 | |||
TMIH-0091 |
AOH-d3
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AOH-d3 是 AOH 的氘代化合物。AOH 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体,靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用,导致 DNA 复制应激,诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用,可抑制肿瘤细胞生长。 | |||
TMIJ-0384 |
L-Cysteine-d3
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L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。 |