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Search Results for " chemicals "

Targets Recommended: Others

27

抑制剂 & 化合物

12

天然产物

12

化合物库

3

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
LF1000	多样性核心预制库		50000 compounds
	For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap.
LF8200	含氟片段化合物库LF		6000 compounds
	The Life Chemicals Fluorine Fragment comprises more than 6,000 fluorine-containing fragments from the General Fragments Stock Collection.
LF9100	丝氨酸靶向共价抑制剂库		2700 compounds
	Over 2,700 small-molecule screening compounds in the library.
LF9200	LC 共价筛选化合物库		34700 compounds

L5200	抗代谢疾病化合物库		1544 compounds
	1544 个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L4500	抗真菌库		252 compounds
	252 个抗真菌活性化合物的独特集合，包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物，是相关疾病药物筛选的有效工具。
L2800	5-羟色胺分子库		268 compounds
	268 种生物活性小分子化合物，用于高通量、高内涵筛选；
LF8700	共价片段化合物库LF		6500 compounds
	The resulting Library comprises over 4,000 small-molecule compounds for covalent fragment screening efforts.
L2610	神经递质受体化合物库		1513 compounds
	1513 种与神经递质受体相关的化合物，用于高通量、高内涵筛选；
L4700	免疫/炎症分子化合物库		4720 compounds
	4720 种具有抗炎症活性的化合物的特有集合，可用于高通量筛选和高内涵筛选；
L8500	HIF-1化合物库		1336 compounds
	1336 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；
L8600	泛素化化合物库		210 compounds
	210 种泛素化相关的小分子，用于高通量和高内涵筛选；

化合物库

多样性核心预制库

Cat.No: LF1000

Compounds: 50000

含氟片段化合物库LF

Cat.No: LF8200

Compounds: 6000

丝氨酸靶向共价抑制剂库

Cat.No: LF9100

Compounds: 2700

LC 共价筛选化合物库

Cat.No: LF9200

Compounds: 34700

抗代谢疾病化合物库

Cat.No: L5200

Compounds: 1544

Cat.No: L4500

Compounds: 252

5-羟色胺分子库

Cat.No: L2800

Compounds: 268

共价片段化合物库LF

Cat.No: LF8700

Compounds: 6500

神经递质受体化合物库

Cat.No: L2610

Compounds: 1513

免疫/炎症分子化合物库

Cat.No: L4700

Compounds: 4720

HIF-1化合物库

Cat.No: L8500

Compounds: 1336

泛素化化合物库

Cat.No: L8600

Compounds: 210

Cat. No.	Product Name	Target	Signaling Pathways
T9365	3-Methyl-2-nitrobenzoic acid	Others	Others
	3-Methyl-2-nitrobenzoic acid 在农药等的制备中用作中间体。
T8239	Cromoglicic acid	Others	Others
	Cromoglicic acid 可防止肥大细胞释放炎性化学物质，例如组胺。
T7842	1H-Pyrazole-3-carboxylic acid	Others	Others
	1H-Pyrazole-3-carboxylic acid 是合成各种药物和农用化学品的重要中间体，也被用作合成吡唑啉酮、吡唑酰胺和吡唑啉等化合物。
T60231	N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine	Others	Others
	N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine 是一种生物活性化合物，属于哌嗪类。它是一种重要的合成中间体，用于制备多种药物、农用化学品和其他化学品。它被认为是参与药物代谢的某些酶的抑制剂，例如细胞色素P450酶，也已被证明具有抗炎和抗肿瘤作用。
T0839L	S-(+)-Ketoprofen RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen,(S)-(+)-酮洛芬,右旋酮洛芬	COX	Immunology/Inflammation; Neuroscience
	S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) 抑制 COX-1和 COX-2的IC50值分别为 1.9 和 27 nM。
T20141	L-6355 L 6355,Amiodarone related compound E,Demonoiodoamiodarone	Others	Others
	L-6355 is an agent of bioactive chemicals.
T20007	Euchrysine 3RX Euchrysine	Others	Others
	Euchrysine 3RX is an agent of bioactive chemicals.
T20086	Hexadecanolactone NSC 33546,BRN 0148631,NSC33546,Hexadecanolide,Juniperic acid lactone,NSC-33546	Others	Others
	Hexadecanolide is an agent of bioactive chemicals.
T20134	L-3373 EINECS 217-773-7	Others	Others
	L-3373 is an agent of bioactive chemicals.
T19998	N-Ethyl tadalafil Homotadalafil,NEthyl tadalafil	Others	Others
	N-Ethyl tadalafil is a compound of bioactive chemicals.
T20044	BAP9THP Acell	Others	Others
	Acell is an agent of bioactive chemicals.
T19997	Daimuron Dymron,Dimuron	Others	Others
	Daimuron is an agent of bioactive chemicals.
T20047	9-Benzyladenine NSC-35649,NSC35649,NSC 35649	Others	Others
	9-Benzyladenine is an agent of bioactive chemicals.
TNU0875	5-O-Triphenylmethoxypentanol	Others	Others
	Intermediates and Building Blocks - Nucleophile; Fine Chemicals
T20171	Bekanamycin sulfate Kanamycin B sulfate,NK 1006,Nebramycin V,Kanendomycin,Stereocidin,Kanendos	Others	Others
	Bekanamycin sulfate is an agent of bioactive chemicals.
T19321	Fenoxaprop-P-ethyl	Others	Others
	Fenoxaprop-P-ethyl, a post-emergent herbicide within the aryloxyphenoxy propionate group, belongs to the phenoxy class of chemicals.
TNU0796	6-Oxo-1,6-dihydropyridazine-3-carboxylic acid methyl ester	Others	Others
	Heterocyclic Compound - Other heterocycle; Intermediate - Electrophile; Fine Chemicals
TNU1454	2-Amino-1,3-benzenediol; 2-Aminoresorcinol	Others	Others
	Fine Chemicals; Intermediates and Building Blocks - Nucleophiles
TNU0917	4-Isopropylphenoxyacetic acid	Others	Others
	Intermediates and Building Blocks - Electrophile; Fine Chemicals
T83377	2-Naphthylamine-6,8-disulfonic acid potassium
	2-Naphthylamine-6,8-disulfonic acid potassium 是一种化学品，它被广泛应用于染料、医药、农药等领域的制备工作中。
TNU0003	2'-O-Methylinosine	Others	Others
	Flame retardant, fine chemicals (plasticizer, functional material); Made by our newly invented process. Used as the flame retardant agent for polyurethane formed hard plastics and as additive in petroleum. It has excellent flame retarding properties because of the phosphorus and chlorine content.
TNU0722	Diethyl (4-aminophenyl)phosphonate	Others	Others
	Diethyl (4-aminophenyl)phosphonate 是一种磷化合物，是一种中间体和结构砌块。它已被用作合成有机化合物的试剂，也被用作合成药物、农用化学品和其他特种化学品的反应物。
TP1647	β-Endorphin, equine
	Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain. Endorphin Beta is produced in response to pain, exercise, and other forms of stress. Endorphin Beta belongs to a group of
T75430	Succinic acid tromethamine	Others	Others
	Succinic acid tromethamine 是一种口服活性抗焦虑剂，有效地参与三羧酸循环作为中间产物。它也广泛用作食品、化学和制药行业中多种重要工业化学品的前体。
T69059	Cromoglicate sodium hydrate	Others	Others
	Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cro...
T35414	α-Cyclodextrin (hydrate)	Others	Others
	α-Cyclodextrin (α-CD) is a saccharide comprised of six glucose subunits linked by α-1,4 bonds, which results in a cone-shaped molecule.1It contains a hydrophobic interior and hydrophilic exterior, which allow it to form inclusion complexes with wide variety of molecules, conferring enhanced solubility and stabilization to the molecules. α-CD has commonly been used in the separation and purification of chemicals on an industrial scale.1,2Formulations containing α-CD have been used in the pharmace...
T36913	17-Epiestriol	Others	Others
	17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme...

化合物

3-Methyl-2-nitrobenzoic acid

Cat.No: T9365

Target: Others

Cromoglicic acid

Cat.No: T8239

Target: Others

1H-Pyrazole-3-carboxylic acid

Cat.No: T7842

Target: Others

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine

Cat.No: T60231

Target: Others

S-(+)-Ketoprofen

Cat.No: T0839L

Synonym: RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen,(S)-(+)-酮洛芬,右旋酮洛芬

Target: COX

Cat.No: T20141

Synonym: L 6355,Amiodarone related compound E,Demonoiodoamiodarone

Target: Others

Cat.No: T20007

Synonym: Euchrysine

Target: Others

Hexadecanolactone

Cat.No: T20086

Synonym: NSC 33546,BRN 0148631,NSC33546,Hexadecanolide,Juniperic acid lactone,NSC-33546

Target: Others

Cat.No: T20134

Synonym: EINECS 217-773-7

Target: Others

N-Ethyl tadalafil

Cat.No: T19998

Synonym: Homotadalafil,NEthyl tadalafil

Target: Others

Cat.No: T20044

Synonym: Acell

Target: Others

Cat.No: T19997

Synonym: Dymron,Dimuron

Target: Others

9-Benzyladenine

Cat.No: T20047

Synonym: NSC-35649,NSC35649,NSC 35649

Target: Others

5-O-Triphenylmethoxypentanol

Cat.No: TNU0875

Target: Others

Bekanamycin sulfate

Cat.No: T20171

Synonym: Kanamycin B sulfate,NK 1006,Nebramycin V,Kanendomycin,Stereocidin,Kanendos

Target: Others

Fenoxaprop-P-ethyl

Cat.No: T19321

Target: Others

6-Oxo-1,6-dihydropyridazine-3-carboxylic acid methyl ester

Cat.No: TNU0796

Target: Others

2-Amino-1,3-benzenediol; 2-Aminoresorcinol

Cat.No: TNU1454

Target: Others

4-Isopropylphenoxyacetic acid

Cat.No: TNU0917

Target: Others

2-Naphthylamine-6,8-disulfonic acid potassium

Cat.No: T83377

2'-O-Methylinosine

Cat.No: TNU0003

Target: Others

Diethyl (4-aminophenyl)phosphonate

Cat.No: TNU0722

Target: Others

β-Endorphin, equine

Cat.No: TP1647

Succinic acid tromethamine

Cat.No: T75430

Target: Others

Cromoglicate sodium hydrate

Cat.No: T69059

Target: Others

α-Cyclodextrin (hydrate)

Cat.No: T35414

Target: Others

Cat.No: T36913

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T8242	Sabinene	Others	Others
	Sabinene 是香料添加剂，具有成为下一代飞机燃料成分的成分。
T4837	Itaconic acid methylene-butanedioicaci,衣康酸	Others; Endogenous Metabolite	Metabolism; Others
	Itaconic acid 是聚合物，化学物质和燃料的合成前体，具有抗炎活性。Itaconic acid可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。
T4848	Mandelic acid acidomandelico,DL-Mandelic acid,扁桃酸	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸，有抗菌活性，广泛用作医药和精细化学品的中间体，已用于研究尿路感染和阴道滴虫病，还具有较高的精子固定活性和较低的阴道刺激性。
T6359	1-Hexadecanol 鲸蜡醇,Cetanol,cetyl alcohol,Hexadecan-1-ol,1-十六烷醇	Others; Endogenous Metabolite	Metabolism; Others
	1-Hexadecanol (Hexadecan-1-ol) 是一种脂肪醇，是亲脂性底物。
TJS1183	Cyclen 轮环藤宁,1,4,7,10-tetraazacyclododecane	Others	Others
	Cyclen (1,4,7,10-tetraazacyclododecane) 是一种氮杂冠醚的类似物，是制备有效的大环螯合物的中间体，是制备磁共振造影剂的前体物质。
T6S0270	Ononin Formononetin 7-O-β-D-glucopyranoside,Formononetin glucoside,Ononoside,芒柄花苷,Formononetin 7-O-glucoside	Antibacterial	Microbiology/Virology
	Ononin (Formononetin 7-O-glucoside) 是一种能够抑制土壤中杂 Pluchea lanceolata 生长的异黄酮。
T8033	Sodium Thiocyanate	Others; Reactive Oxygen Species; Interleukin	Immunology/Inflammation; Metabolism; NF-κB; Others
	Sodium thiocyanate 能够减少促炎细胞因子 IL-6水平，并增强抗炎细胞因子 IL-10水平，并显著减少 ROS 形成。
T8051	Bis(2-methyl-3-furyl)disulfide 双(2-甲基-3-呋喃基)二硫,Bis(2-methyl-3-furyl)disulphide	Others	Others
	Bis(2-methyl-3-furyl)disulphide 是调味剂，能够增强与牛奶相关的产品的自然感，清新感。
T7977	Benzofuroxan	Others	Others
	Benzofuroxan 被用作合成其他化合物的起始材料，如药物和其他化学品；也用于聚合物的合成；还被用于合成荧光染料，并作为检测某些分子的荧光探针。
TN6742	β-Damascone Damascone,大马酮	Others	Others
	β-Damascone 是具有香气活性的大米挥发物，普遍用于香水成分中。它具有用作癌症化学预防剂及蚊香类杀虫剂的潜力。
T41122	1,3-Dihydroxyacetone	Endogenous Metabolite	Metabolism
	1,3-Dihydroxyacetone 是防晒美黑护肤制剂的主要活性成分，是合成各种精细化学品的重要前体，也是一种食品添加剂，可通过在 Gluconobacter oxydans 上进行微生物发酵实现工业规模生产。1,3-Dihydroxyacetone 具有提高cAMP 水平的能力。
TN6564	Palustrol
	Palustrol exhibits acaricidal, insecticidal, 'pesticidal' and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance.

天然产物

Cat.No: T8242

Target: Others

Cat.No: T4837

Synonym: methylene-butanedioicaci,衣康酸

Target: Others, Endogenous Metabolite

Cat.No: T4848

Synonym: acidomandelico,DL-Mandelic acid,扁桃酸

Target: Others, Endogenous Metabolite, Antibacterial

Cat.No: T6359

Synonym: 鲸蜡醇,Cetanol,cetyl alcohol,Hexadecan-1-ol,1-十六烷醇

Target: Others, Endogenous Metabolite

Cat.No: TJS1183

Synonym: 轮环藤宁,1,4,7,10-tetraazacyclododecane

Target: Others

Cat.No: T6S0270

Synonym: Formononetin 7-O-β-D-glucopyranoside,Formononetin glucoside,Ononoside,芒柄花苷,Formononetin 7-O-glucoside

Target: Antibacterial

Sodium Thiocyanate

Cat.No: T8033

Target: Others, Reactive Oxygen Species, Interleukin

Bis(2-methyl-3-furyl)disulfide

Cat.No: T8051

Synonym: 双(2-甲基-3-呋喃基)二硫,Bis(2-methyl-3-furyl)disulphide

Target: Others

Cat.No: T7977

Target: Others

Cat.No: TN6742

Synonym: Damascone,大马酮

Target: Others

1,3-Dihydroxyacetone

Cat.No: T41122

Target: Endogenous Metabolite

Cat.No: TN6564

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His) HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotransferase family, cyt...	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa...
TMPJ-00813	QDPR Protein, Human, Recombinant (His) Dihydropteridine Reductase,QDPR,DHPR,HDHPR,Quinoid Dihydropt...	Human	HEK293 Cells
	Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals i...
TMPY-02223	GSTM2 Protein, Human, Recombinant (His) GSTM2-2,GTHMUS,glutathione S-transferase mu 2 (muscle),GSTM,...	Human	E. coli
	Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si...

重组蛋白

SULT1A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02062

Species: Human

Expression System: E. coli

QDPR Protein, Human, Recombinant (His)

Cat.No: TMPJ-00813

Species: Human

Expression System: HEK293 Cells

GSTM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02223

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0207	(S)-Ketoprofen-d3
	(S)-Ketoprofen-d3 是 (S)-Ketoprofen 的氘代化合物。(S)-Ketoprofen 的 CAS 号为 22161-81-5。S-(+)-Ketoprofen 抑制COX-1和COX-2的IC50值分别为 1.9 和 27 nM。

同位素标记化合物

(S)-Ketoprofen-d3

Cat.No: TMIJ-0207

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