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Search Results for " antithrombotic "
Targets Recommended: Factor Xa

67

抑制剂 & 化合物

13

天然产物

3

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1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T4980 Betrixaban maleate

Factor Xa Metabolism
Betrixaban maleate 是一种非维生素 K 口服抗凝剂,其作用是由 Xa 因子的竞争性和可逆抑制作用驱动的。
T3536 AZD1283

P2Y Receptor GPCR/G Protein; Neuroscience
AZD1283是P2Y12受体拮抗剂,EC50为3.0 ug/kg/min,结合的IC50为11 nM。它剂量依赖性地诱导血流量增加和抑制 ADP 诱导的血小板聚集,抗血栓形成的 ED50 值分别为 3.0 和 10 μg/kg/min。
T4132 BPTU

BMS-646786

P2Y Receptor GPCR/G Protein; Neuroscience
BPTU (BMS-646786) 是一种非核苷酸类P2Y1受体变构拮抗剂,能够阻断位于胃肠道神经肌肉接头的 P2Y1受体,具有抗血栓活性。
T0435 Sulfinpyrazone

(+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925

COX Immunology/Inflammation; Neuroscience
Sulfinpyrazone (NSC-75925) 是一种口服有效的尿酸剂,具有抗血栓和血小板抑制作用。它可作用于慢性和间歇性痛风性关节炎。
T0389 Dabigatran etexilate

达比加群酯,BIBR 1048

Thrombin Proteases/Proteasome
Dabigatran etexilate (BIBR 1048) 是一种 Dabigatran 前药,具有口服活性。它具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。
T4190 Ticlopidine

PCR 5332,Ticlid,噻氯匹定

ATPase; Adiponectin receptor GPCR/G Protein; Membrane transporter/Ion channel
Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂,抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂,能够阻断 NTPDase 同工酶,对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
T31206 Darexaban

YM 150,Darexaban, Tanexaban,YM150

Factor Xa Metabolism
Darexaban (Tanexaban, YM-150) 是选择性的、口服具有活力的 Xa 因子 (FXa) 抑制剂,IC50=54.6 nM。它对其他相关丝氨酸蛋白酶(如胰蛋白酶、凝血酶和激肽释放酶)具有高选择性。它具有抗凝和抗血栓形成作用。
T6182 Tirofiban

L700462,Aggrastat,替罗非班,MK383

Integrin Cytoskeletal Signaling
Tirofiban (L700462) 是一种非肽类选择性 GPIIb/IIIa 拮抗剂,IC50 为 9 nM,可抑制血小板聚集。
T5133 Dabigatran Etexilate Mesylate

甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate

Thrombin Proteases/Proteasome
Dabigatran Etexilate Mesylate (BIBR 1048MS) 是一种口服具有活性的 Dabigatran 前药,具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。
T2537 Tirofiban hydrochloride monohydrate

Tirofiban Hydrochloride,盐酸替罗非班水合物,MK-383 Hydrochloride,盐酸替罗非班

ATPase; Integrin Cytoskeletal Signaling; Membrane transporter/Ion channel
Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) 是一种非肽类糖蛋白IIb/IIIa 的拮抗剂。
T0182L Clopidogrel hydrogen sulfate

硫酸氢氯吡格雷,(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel,硫酸氯吡格雷

P450; P2Y Receptor GPCR/G Protein; Metabolism; Neuroscience
Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) 是一种抗血小板药物,可防止血栓形成。它抑制 CYP2B6和 CYP2C19,IC50分别为 18.2 和 524 nM。 它是一种选择性的高亲和力 P2Y12 受体拮抗剂,可抑制纤维蛋白原与血小板的结合以及血小板的粘附和聚集。
T2368 Edoxaban Tosylate Monohydrate

DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物

Factor Xa; Thrombin Metabolism; Proteases/Proteasome
Edoxaban Tosylate Monohydrate (DU-176b tosylate Monohydrate) 是口服具有活力的 factor Xa 选择性抑制剂。它是一种抗凝剂,可用于预防中风,是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂,对 FXa 的选择性超过 10000 倍。它具有抗血栓形成的特性,可用于血栓栓塞性疾病的研究。
T67991 Iliparcil

Others Others
Iliparcil 是一种具有口服活性的抗血栓化合物。
T4076 Fondaparinux sodium

Natural heparin pentasaccharide Sodium,Fondaparin sodium,磺达肝素(癸)钠,磺达肝癸钠,SR-90107A,Arixtra

Factor Xa Metabolism
Fondaparinux sodium (SR-90107A) 是抗凝血酶依赖性的 factor Xa 抑制剂。
T13210 Trombodipine

PCA-4230

Antibiotic Microbiology/Virology
Trombodipine (PCA-4230) 是一种血小板聚集抑制剂,具有抗血栓活性,对单核细胞增生李斯特菌具有保护作用。
T80792 WAY-639228

Others Others
WAY-639228-A 具有潜在的抗血栓和抗凝活性,可用于研究脑血栓。
T25741 Linotroban

HN 11500,CL-871502

PPAR DNA Damage/DNA Repair; Metabolism
Linotroban(CL-871502) 是一种有效的选择性血栓素(TXA2)受体拮抗剂,具有抗血栓活性。
T27920 LY 517717

LY-517717,LY517717

Factor Xa Metabolism
LY 517717 是一种具有口服活性的凝血因子 Xa 抑制剂,具有抗血栓活性,可用于研究静脉血栓栓塞(VTE)。
T27318 Fidexaban

CI-1031,BX-807834,PD-200022,CI1031,BX807834,ZK-807834

Factor Xa Metabolism
Fidexaban (CI1031) 是一种新型、强效、选择性和口服活性 Xa 因子抑制剂,在多种测定中均显示出抗血栓活性。
T17025 Tecarfarin

ATI-5000,ATI-5923

Others Others
Tecarfarin (ATI-5923) 是一种具有口服活性和有效性的维生素 K 环氧化物还原酶 (VKOR) 拮抗剂和大麻素-1受体反向激动剂,具有抗血栓形成活性,可减轻小鼠的腹痛并增加肠道转运。
T3757 NQ301

Thrombin; Platelet aggregation Others; Proteases/Proteasome
NQ301 是一种抗血栓剂,能够抑制胶原蛋白激发的兔血小板聚集,IC50=10 mg/mL。
T9620 Sodium Tetradecyl Sulfate

Others Others
Sodium Tetradecyl Sulfate 是洗涤剂硬化剂,常用于静脉曲张及食管静脉的治疗。
T24542 NP-313

NP 313,NSC 4264,NSC-4264,NSC4264

Others Others
NP-313 (NSC-4264) 是一种有效的抗血栓剂,对血栓素 A 2 合成和选择性抑制由 SOCC 介导的 Ca 2+ 内流有抑制作用,可以抑制血小板的聚集和活化。
T3469 PCI-27483

PCI27483

Others Others
PCI-27483 是一种FVIIa/tissue factor 抑制剂,具有抗肿瘤的作用。
T8580 Bupranolol

Adrenergic Receptor GPCR/G Protein; Neuroscience
Bupranolol 是竞争性的、口服活性的、非选择性的β-adrenoceptor 拮抗剂,无固有的拟交感神经活性。
T37299 L-Palmitoylcarnitine chloride

Palmitoyl-L-carnitine chloride

ATPase Membrane transporter/Ion channel
L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物,具有抗血栓形成的作用,通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵,抑制 FeCl 3诱导的动脉血栓形成,减轻了短暂性大脑中动脉闭塞(tMCAO)小鼠模型的脑内血栓形成和炎症。
T63966 BMS-986141

UDM-003183

Protease-activated Receptor GPCR/G Protein
BMS-986141(UDM-003183) 是一种具有口服活性的选择性和高效性的凝血酶受体蛋白酶激活受体-4 (protease-activated receptor-4 (PAR-4)) 拮抗剂,其 IC50 值为 0.4 nM。BMS-98614 表现出显著的抗血栓作用。
T71641 BMS-593214

Others Others
BMS-593214 是一种活性位点定向因子 (F)VIIa 抑制剂。BMS-593214 具有抗血栓和抗出血特性。BMS-593214 是人 FVIIa 的直接竞争性抑制,也是 VIIa 激活底物 FX 的非竞争性抑制剂。BMS-593214 预防电诱导颈动脉血栓形成 (AT)、线诱导腔静脉血栓形成 (VT)。
T16328 Nitroaspirin

2-乙酰氧基苯甲酸-3-硝酸甲基苯酯,NCX 4016

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Nitroaspirin (NCX 4016) 是一氧化氮供体和阿司匹林的硝基衍生物,与 Aspirin 结合可抑制环氧合酶=,可作为 COX-1 的直接和不可逆抑制剂。 它通过下调 EGFR/PI3K/STAT3 信号传导和调节 Bcl-2 家族蛋白,显着诱导顺铂耐药人卵巢癌细胞的细胞周期停滞和凋亡,具有抗血栓和抗血小板特性。
T68002 Naroparcil

Thrombin Proteases/Proteasome
Naroparcil 是一种可口服的硫代苷类化合物,是一种 4-甲基伞形 β-D-木糖苷类似物,在静脉血栓形成(颈静脉)的Wessler淤滞模型中显示出抗血栓形成作用。Naroparcil 增强了凝血酶/肝素辅因子II复合物的形成,诱导了处理兔血浆中硫酸皮肤素样物质的出现,但减少了与(125I)-人α-凝血酶孵育的血浆中的凝血酶/抗凝血酶III复合物的形成。
T2368L Edoxaban

Lixiana,依杜沙班

Factor Xa; Thrombin Metabolism; Proteases/Proteasome
Edoxaban (Lixiana) (DU-176) 是一种选择性的,口服有效的 factor Xa (FXa)抑制剂。Edoxaban 对游离 FXa 和凝血酶原的 Ki 分别为 0.561 nM 和 2.98 nM。Edoxaban 是一种抗凝剂,可用于预防中风。Edoxaban 还是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂,Ki 值分别为 6.00 μM 和 41.7 μM,对 FXa 的选择性超过 10000 倍。由于具有抗血栓形成的特性,Edoxaban 可用于预防血栓栓塞性疾病的研究。
T29070 Uproleselan

Others Others
Uproleselan has antithrombotic and antineoplastic properties.
T30186 AT-1459

UNII-JWP323ABVS

Others Others
AT-1459 is a novel direct thrombin inhibitor with antithrombotic efficacy.
T21471 Dazoxiben free base

Dazoxiben hydrochloride,Dazoxiben hydrochloride, Dazoxiben HCl,Dazoxiben hydrochloride, UK-37,248-01

Others Others
Dazoxiben is an antithrombotic agent used to reduce the formation of blood clots.
T68719 Ro 15-2041

Others Others
Ro 15-2041 is a selective platelet camp phosphodiesterase inhibitor with antithrombotic properties.
T70737 HN 11500

Others Others
HN 11500 is an antithrombotic agent and thromboxane A2 receptor antagonist.
T12741 Ro-15-2041

Others Others
Ro 15-2041 is a selective inhibitor of platelet phosphodiesterase, with antithrombotic properties.
T17024 Tecarfarin sodium

ATI-5923 sodium

Others Others
Tecarfarin sodium is a novel orally active non-competitive vitamin K epoxide reductase antagonist. Tecarfarin sodium has the antithrombotic activity.
T17091 Thrombin Inhibitor 2

Others Others
Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.
T15256 Etofylline clofibrate

Others Others
Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.
T26874 BN 50341

BN50341,BN-50341

Others Others
BN 50341 is an inhibitor of antithrombotic platelet activating factor.
T70458 FXIa-6f

Others Others
FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species
T28909 TA-993 maleate

TA 993,TA993,TA-993

Others Others
TA-993 is a calcium channel antagonist. TA-993 has an antithrombotic effect.
T70909 AY 31390

Others Others
AY 31390 is a phosphodiesterase (PDE) inhibitor with antithrombotic activity.
T70536 Idraparinux Na

Others Others
Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor
T24898 Trifenagrel

BW-325U,BW 325U,BW325U

Others Others
Trifenagrel is an antithrombotic. It has been found to produce less gastric irritation and fecal blood loss in humans.
T80512 Thrombin receptor peptide ligand

Thrombin Proteases/Proteasome
Thrombin receptor peptide ligand为凝血酶受体的一种拮抗肽,用于抗血栓治疗。
T12782 RWJ-445167

3DP-10017

Factor Xa; Thrombin Metabolism; Proteases/Proteasome
RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.
T12694 Razaxaban hydrochloride

BMS 561389 hydrochloride,DPC 906 hydrochloride

Others Others
Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.
T29190 YM-75466

YM 466,YM-466,YM75466,YM 75466,YM-75466 Free

Others Others
YM-75466 is a factor Xa inhibitor. YM-75466 did not prolong coagulation time even at the dose which exerted significant antithrombotic effects, while it decreased TAT level in plasma in a dose-dependent manner.

化合物

Betrixaban maleate
Cat.No: T4980
Synonym:
Target: Factor Xa
AZD1283
Cat.No: T3536
Synonym:
Target: P2Y Receptor
BPTU
Cat.No: T4132
Synonym: BMS-646786
Target: P2Y Receptor
Sulfinpyrazone
Cat.No: T0435
Synonym: (+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925
Target: COX
Dabigatran etexilate
Cat.No: T0389
Synonym: 达比加群酯,BIBR 1048
Target: Thrombin
Ticlopidine
Cat.No: T4190
Synonym: PCR 5332,Ticlid,噻氯匹定
Target: ATPase, Adiponectin receptor
Darexaban
Cat.No: T31206
Synonym: YM 150,Darexaban, Tanexaban,YM150
Target: Factor Xa
Tirofiban
Cat.No: T6182
Synonym: L700462,Aggrastat,替罗非班,MK383
Target: Integrin
Dabigatran Etexilate Mesylate
Cat.No: T5133
Synonym: 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate
Target: Thrombin
Tirofiban hydrochloride monohydrate
Cat.No: T2537
Synonym: Tirofiban Hydrochloride,盐酸替罗非班水合物,MK-383 Hydrochloride,盐酸替罗非班
Target: ATPase, Integrin
Clopidogrel hydrogen sulfate
Cat.No: T0182L
Synonym: 硫酸氢氯吡格雷,(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel,硫酸氯吡格雷
Target: P450, P2Y Receptor
Edoxaban Tosylate Monohydrate
Cat.No: T2368
Synonym: DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物
Target: Factor Xa, Thrombin
Iliparcil
Cat.No: T67991
Synonym:
Target: Others
Fondaparinux sodium
Cat.No: T4076
Synonym: Natural heparin pentasaccharide Sodium,Fondaparin sodium,磺达肝素(癸)钠,磺达肝癸钠,SR-90107A,Arixtra
Target: Factor Xa
Trombodipine
Cat.No: T13210
Synonym: PCA-4230
Target: Antibiotic
WAY-639228
Cat.No: T80792
Synonym:
Target: Others
Linotroban
Cat.No: T25741
Synonym: HN 11500,CL-871502
Target: PPAR
LY 517717
Cat.No: T27920
Synonym: LY-517717,LY517717
Target: Factor Xa
Fidexaban
Cat.No: T27318
Synonym: CI-1031,BX-807834,PD-200022,CI1031,BX807834,ZK-807834
Target: Factor Xa
Tecarfarin
Cat.No: T17025
Synonym: ATI-5000,ATI-5923
Target: Others
NQ301
Cat.No: T3757
Synonym:
Target: Thrombin, Platelet aggregation
Sodium Tetradecyl Sulfate
Cat.No: T9620
Synonym:
Target: Others
NP-313
Cat.No: T24542
Synonym: NP 313,NSC 4264,NSC-4264,NSC4264
Target: Others
PCI-27483
Cat.No: T3469
Synonym: PCI27483
Target: Others
Bupranolol
Cat.No: T8580
Synonym:
Target: Adrenergic Receptor
L-Palmitoylcarnitine chloride
Cat.No: T37299
Synonym: Palmitoyl-L-carnitine chloride
Target: ATPase
BMS-986141
Cat.No: T63966
Synonym: UDM-003183
Target: Protease-activated Receptor
BMS-593214
Cat.No: T71641
Synonym:
Target: Others
Nitroaspirin
Cat.No: T16328
Synonym: 2-乙酰氧基苯甲酸-3-硝酸甲基苯酯,NCX 4016
Target: Apoptosis, COX
Naroparcil
Cat.No: T68002
Synonym:
Target: Thrombin
Edoxaban
Cat.No: T2368L
Synonym: Lixiana,依杜沙班
Target: Factor Xa, Thrombin
Uproleselan
Cat.No: T29070
Synonym:
Target: Others
AT-1459
Cat.No: T30186
Synonym: UNII-JWP323ABVS
Target: Others
Dazoxiben free base
Cat.No: T21471
Synonym: Dazoxiben hydrochloride,Dazoxiben hydrochloride, Dazoxiben HCl,Dazoxiben hydrochloride, UK-37,248-01
Target: Others
Ro 15-2041
Cat.No: T68719
Synonym:
Target: Others
HN 11500
Cat.No: T70737
Synonym:
Target: Others
Ro-15-2041
Cat.No: T12741
Synonym:
Target: Others
Tecarfarin sodium
Cat.No: T17024
Synonym: ATI-5923 sodium
Target: Others
Thrombin Inhibitor 2
Cat.No: T17091
Synonym:
Target: Others
Etofylline clofibrate
Cat.No: T15256
Synonym:
Target: Others
BN 50341
Cat.No: T26874
Synonym: BN50341,BN-50341
Target: Others
FXIa-6f
Cat.No: T70458
Synonym:
Target: Others
TA-993 maleate
Cat.No: T28909
Synonym: TA 993,TA993,TA-993
Target: Others
AY 31390
Cat.No: T70909
Synonym:
Target: Others
Idraparinux Na
Cat.No: T70536
Synonym:
Target: Others
Trifenagrel
Cat.No: T24898
Synonym: BW-325U,BW 325U,BW325U
Target: Others
Thrombin receptor peptide ligand
Cat.No: T80512
Synonym:
Target: Thrombin
RWJ-445167
Cat.No: T12782
Synonym: 3DP-10017
Target: Factor Xa, Thrombin
Razaxaban hydrochloride
Cat.No: T12694
Synonym: BMS 561389 hydrochloride,DPC 906 hydrochloride
Target: Others
YM-75466
Cat.No: T29190
Synonym: YM 466,YM-466,YM75466,YM 75466,YM-75466 Free
Target: Others
Cat. No. Product Name Target Signaling Pathways
T13302 Viquidil hydrochloride

Quinotoxine hydrochloride

Others Others
Viquidil hydrochloride (Quinotoxine hydrochloride) 是奎尼丁的同分异构体,是一种脑血管扩张剂,具有抗血栓作用。
T4853 TRIA-662

3-Carbamoyl-1-methylpyridinium Chloride,3-氨基甲酰-1-甲基氯化吡啶,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate

Others; Endogenous Metabolite Metabolism; Others
TRIA-662 (Nicotinamide Chloromethylate) 是内源性代谢产物的一种。
T3817 Darutigenol

Others Others
Darutigenol 是一种戊二萜,从Siegesbecikia orientalis L.中分离得到。
T2S0504 Ilexoside D

Others Others
Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.
T8121 Octacosanoic acid

Anti-infection Microbiology/Virology
Octacosanoic acid 具有抗血小板和抗血栓作用。
T8061 Citronellal

(±)-Citronellal,香茅醛

Others Others
Citronellal ((±)-Citronellal) 是多种芳香植物精油的单萜烯,具有促进睡眠、安定和抗伤害的作用。它可以降低机械伤害感受,且部分通过 NO-cGMP-ATP 敏感型 K⁺渠道通道介导的。
T2S1749 Protogracillin

原纤细薯蓣皂甙

Others Others
Protogracillin 是一种甾体皂苷,分离自Dioscorea zingiberensisWright (DZW) 中。从 DZW 根状茎中获得的甾体皂苷具有抗血栓作用,同时由降低心血管疾病风险的潜力。
T5725 Salvianolic acid B

丹酚酸B,lithospermic acid B,Dan Shen Suan B

Sirtuin; Autophagy Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参的天然产物,是一种抗氧化剂,具有水溶性。Salvianolic acid B 具有抗血小板聚集、抗凝和抗血栓作用,常用来研究微循环疾病。
T2727 Salvianolic acid B

Others Others
Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参提取物的水溶性抗氧化剂,具有抗血小板聚集、抗凝和抗血栓作用。它常用来研究微循环疾病。
TN1996 Nothofagin

ERK; IL Receptor; TNF Apoptosis; Immunology/Inflammation; MAPK
Nothofagin 具有抗氧化和抗血栓活性,它通过抑制高渗透性、CAMs 的表达以及白细胞的粘附和迁移具有抗炎活性,从而支持其作为血管炎症性疾病的治疗作用。
T4S0498 Glaucocalyxin A

蓝萼甲素,Wangzaozin B,Leukamenin F

Apoptosis; Akt; Caspase; PI3K Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Glaucocalyxin A (Leukamenin F) 是来自日本黑纹病菌的一种对映型月桂基二萜,具有抗肿瘤作用。它通过调节PI3K/Akt 信号通路抑制 GLI1 的核易位,诱导骨肉瘤凋亡。
TN2002 Obovatol

BCL; Caspase; JAK Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Proteases/Proteasome; Stem Cells
Obovatol has antioxidant, neuroprotective, antiinflammatory, antithrombotic and antitumour effects, it is a potent NF-κB inhibitors for Alzheimer's disease treatment.
T5794 Saponin C from Liriope muscari

Liriope muscari baily Saponins C

Autophagy Autophagy
Saponin C from Liriope muscari 可从百合科植物 Liriope muscari中提取,具有抗血栓活性,可诱导自噬。

天然产物

Viquidil hydrochloride
Cat.No: T13302
Synonym: Quinotoxine hydrochloride
Target: Others
TRIA-662
Cat.No: T4853
Synonym: 3-Carbamoyl-1-methylpyridinium Chloride,3-氨基甲酰-1-甲基氯化吡啶,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate
Target: Others, Endogenous Metabolite
Darutigenol
Cat.No: T3817
Synonym:
Target: Others
Ilexoside D
Cat.No: T2S0504
Synonym:
Target: Others
Octacosanoic acid
Cat.No: T8121
Synonym:
Target: Anti-infection
Citronellal
Cat.No: T8061
Synonym: (±)-Citronellal,香茅醛
Target: Others
Protogracillin
Cat.No: T2S1749
Synonym: 原纤细薯蓣皂甙
Target: Others
Salvianolic acid B
Cat.No: T5725
Synonym: 丹酚酸B,lithospermic acid B,Dan Shen Suan B
Target: Sirtuin, Autophagy
Salvianolic acid B
Cat.No: T2727
Synonym:
Target: Others
Nothofagin
Cat.No: TN1996
Synonym:
Target: ERK, IL Receptor, TNF
Glaucocalyxin A
Cat.No: T4S0498
Synonym: 蓝萼甲素,Wangzaozin B,Leukamenin F
Target: Apoptosis, Akt, Caspase, PI3K
Obovatol
Cat.No: TN2002
Synonym:
Target: BCL, Caspase, JAK
Saponin C from Liriope muscari
Cat.No: T5794
Synonym: Liriope muscari baily Saponins C
Target: Autophagy
Cat. No. Product Name Species Expression System
TMPH-03210 TFPI Protein, Rabbit, Recombinant (E. coli, His)

Lipoprotein-associated coagulation inhibitor,Extrinsic pathw...

Rabbit E. coli
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761.
TMPH-03211 TFPI Protein, Rabbit, Recombinant (His)

TFPI,Lipoprotein-associated coagulation inhibitor,Extrinsic ...

Rabbit HEK293 Cells
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is P19761.
TMPJ-00802 THBS1 Protein, Human, Recombinant (His)

TSP,TSP1,Thrombospondin-1,THBS1

Human HEK293 Cells
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 contains an N-terminal Laminin G-like globular domain, an extended central region with one vWFC domain, 3 TSP type 1domains, 2 EGF-like domains, and 8 TSP type3 domains, and a globular TSP C-terminal domain. Distinct regions of TSP-1 have...

重组蛋白

TFPI Protein, Rabbit, Recombinant (E. coli, His)
Cat.No: TMPH-03210
Species: Rabbit
Expression System: E. coli
TFPI Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03211
Species: Rabbit
Expression System: HEK293 Cells
THBS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00802
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMID-0040 Palmitoyl L-Carnitine-d3 Hydrochloride

Palmitoyl L-Carnitine-d3 Hydrochloride 是 Palmitoyl L-Carnitine Hydrochloride 的氘代化合物。Palmitoyl L-Carnitine Hydrochloride 的 CAS 号为 18877-64-0。L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物,具有抗血栓形成的作用,通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵,抑制 FeCl 3诱导的动脉血栓形成,减轻了短暂性大脑中动脉闭塞(tMCAO)小鼠模型的脑内血栓形成和炎症。

同位素标记化合物

Palmitoyl L-Carnitine-d3 Hydrochloride
Cat.No: TMID-0040
Synonym:
Target:
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