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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T83675 |
Thio-NAD
Thionicotinamide NAD,Thionicotinamide adenine dinucleotide |
||
Thio-NAD是一种经硫酮改造的信号分子和酶辅因子NAD+的衍生物。它能够在碱性磷酸酶(ALP)酶活性检测中替代NAD+作为辅因子。Thio-NAD被用作双酶循环ELISA的底物,以识别严重急性呼吸综合征冠状病毒2(SARS-CoV-2)刺突糖蛋白,亦称为表面糖蛋白,以及患者痰液中的活M. tuberculosis细菌。其在405 nm处表现出吸收,使其能够与其他辅因子区分开来。 | |||
T73616 |
Glutamate dehydrogenase (NAD(P))
GLDH |
Mitochondrial Metabolism | Metabolism |
Glutamate dehydrogenase NAD(P) (GLDH)是一种线粒体酶,广泛存在于生物体内,催化谷氨酸可逆的氧化脱氨生成 α-酮戊二酸 (α-KG),可用于研究谷氨酸代谢异常引起的疾病。 | |||
T36304 |
Fluorescein-NAD+
|
Others | Others |
Fluoroscein NAD+ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled NAD for use in PARP assays. Allows direct measurement of NAD-dependent enzymes, such as PARP, by fluorescence microscopy. This product is a replacement for R&D Systems product 4673-500-01 81 μg is supplied as 250 μl of a 0.25 mM solution in water. | |||
T83799 |
6-alkyne NAD+ sodium
β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD |
||
6-炔基NAD+是一种可点击的信号分子及酶辅因子NAD+形式。它与荧光标签联用,用于检测聚(ADP-核糖)聚合酶(PARP)蛋白质底物。 | |||
T38730 |
Ara-F-NAD+
|
Others | Others |
Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM. | |||
T23050 |
NAD 299 hydrochloride
|
Others | Others |
Selective, high affinity 5-HT1A receptor antagonist | |||
T33565 |
NAAD sodium salt
NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD |
Others | Others |
NAAD sodium salt (NAAD Na salt) 是烟酰胺腺嘌呤二核苷酸合酶的底物,可用于研究底物的特异性和动力学。 | |||
T83845 |
8-(4-azidophenacylthio) NAD+ sodium
Click Tag™ 8-(4-azidophenacylthio) NAD+,8-(4-azidophenacylthio) Nicotinamide adenine dinucleotide |
||
8-(4-azidophenacylthio) NAD+ 是NAD+信号分子及酶辅因子的一种可点击形式。 | |||
T83844 |
8-(2-azidobenzylthio) NAD+ sodium
8-(2-azidobenzylthio) Nicotinamide adenine dinucleotide,Click Tag™ 8-(2-azidobenzylthio) NAD+ |
||
8-(2-azidobenzylthio) NAD+ 是一种可点击形式的信号分子及酶辅因子NAD+。 | |||
T75289 |
NAD sodium
|
Others | Others |
NAD sodium(β-Nicotinamide Adenine Dinucleotide sodium)为NAD的同类物,能在有机底物氧化反应中被还原为β-烟酰胺腺嘌呤二核苷酸(NADH)。此外,NAD sodium转化成的NADH能传递至线粒体内,间接促进ATP的生成。 | |||
T24721 |
Robalzotan
NAD-299,AZD 7371,AZD7371,NAD 299,AZD-7371 |
Others | Others |
Robalzotan is a selective 5-HT1A receptor antagonist. | |||
T78408 |
Nicotinamide 1,N6-ethenoadenine dinucleotide
ε-NAD |
||
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) 是一种NAD的荧光类似物,它可作为底物参与细菌毒素催化的信号转导G蛋白G-ADP核糖基化反应。此外,ε-NAD还常用作ADP核糖基化反应研究的荧光底物。 | |||
T76159 |
Aldehyde dehydrogenase (NAD(P))
|
Others | Others |
Aldehyde dehydrogenaseNAD(P) (ALDH) 催化醛氧化成相应的羧酸,伴随辅因子 NAD(P) 还原成 NAD(P)H,常用于生化研究。Aldehyde dehydrogenaseNAD(P) 是人体用来缓解乙醛应激的许多酶系统之一。 | |||
T31261 |
Deaminocozymase
Deamino-NAD,Deamino DPN,Nicotinamide-hypoxanthine dinucleotide,Deamino NAD,Desamino-DPN |
Others | Others |
Deaminocozymase also known as Nicotinamide-hypoxanthine dinucleotide, is a biochemical. | |||
T83800 |
6-Biotin-17-NAD+ sodium
6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide |
||
6-Biotin-17-NAD+ 是信号分子及酶辅因子NAD+的生物素化衍生物,已应用于高通量筛选(HTS)中,用于测定线粒体复合物I(又称NADH脱氢酶)的活性。 | |||
T74032 |
Ara-F-NAD+ sodium
|
Others | Others |
Ara-F-NAD+ sodium 是一种 NAD+的 arabino 类似物。Ara-F-NAD+ sodium 是一种有效的、可逆的、缓慢结合的CD38NADase 抑制剂。 | |||
T83798 |
8-bromo NAD+ sodium
8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+ |
Others | Others |
8-bromo NAD+ 作为循环ADP-核糖(cADPR)抑制剂8-bromo cADPR的前药形式,通过CD38转化为8-bromo-cADPR。在1 mM浓度下,8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时,在100 µM浓度下使用,减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。 | |||
T38163 |
ML-148
|
Dehydrogenase | Metabolism |
ML-148 是 15-羟基前列腺素脱氢酶 (15-PGDH, IC50 = 56 nM) 的特异性抑制剂。 ML-148 可用于分析一组相关的脱氢酶或还原酶以及有关前列腺素信号通路的研究。 | |||
T6912 |
NU1025
NSC 696807 |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
NU1025 (NSC-696807) 是一种PARP 的有效抑制剂,IC50为 400 nM,Ki 为 48 nM。它可增强电离辐射和抗癌药物的细胞毒性,有抗癌和神经保护的作用。 | |||
T12854 |
SBI-797812
|
NAMPT | Metabolism |
SBI-797812 是在结构上类似于活性位点定向的 NAMPT 抑制剂的化合物,能够阻断这些抑制剂与 NAMPT 的结合。 它将 NAMPT 反应平衡转向 NMN 形成,提高 NAMPT 对 ATP 的亲和力,稳定 His247 处的磷酸化 NAMPT,增加焦磷酸盐副产物的消耗,并通过 NAD+钝化反馈抑制。 | |||
T19467 |
NADPH tetracyclohexanamine
还原型辅酶II四钠,NADPH (tetracyclohexanamine) |
Ferroptosis | Apoptosis |
NADPH tetracyclohexanamine (NADPH(tetracyclohexanamine)) 是一种辅助因子和生物还原剂。 | |||
T6851 |
NADP sodium salt
Sodium NADP,三磷酸吡定核苷酸,辅酶Ⅱ(NADP 钠盐) |
Others | Others |
NADP sodium salt (Sodium NADP) 是一种烟酰胺腺嘌呤二核苷酸,是一种氧化还原辅助因子。它是代谢中电子转移的关键辅因子,能够被交替氧化 (NADP+) 和还原 (NADPH)。 | |||
T1466 |
Nadifloxacin
OPC7251,那氟沙星 |
Antibacterial; Antibiotic | Microbiology/Virology |
Nadifloxacin (OPC7251) 是一种对粉刺有效的广谱氟喹诺酮类抗生素。 | |||
T28294 |
Panadiplon
FG10571,FG-10571,FD-10571,PNU 78875,FG 10571,FD10571,FD 10571 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Panadiplon (FG 10571) 是一种具有选择性的γ-氨基丁酸受体激动剂和5GABAA 的部分激动剂,是一种苯二氮卓类受体,可用于治疗焦虑症。Panadiplon 对 5GABAA 受体与 1GABAA 受体表现出选择性。 | |||
T16980 |
Taminadenant
|
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Taminadenant 是一种腺苷受体拮抗剂。 | |||
T2189 |
Sodium orthovanadate
Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate |
ATPase; Phosphatase | Membrane transporter/Ion channel; Metabolism |
Sodium orthovanadate 是一种蛋白酪氨酸磷酸酶,碱性磷酸酶和一些ATP 酶的抑制剂,有可能充当磷酸盐类似物。它具有胰岛素样作用、对心室肌的正性肌力作用和其他代谢作用。 | |||
T27627 |
Iroxanadine
BRX005,BRX-235,BRX-005,BRX235,BRX 005,BRX 235 |
p38 MAPK | MAPK |
Iroxanadine (BRX-005) 是一种新型小分子MAPK p38 抑制剂,诱导p38 SAPK 的磷酸化,在用去氧肾上腺素预先收缩的豚鼠肺动脉制剂中诱导浓度依赖性松弛,可用于治疗动脉粥样硬化、糖尿病血管病,微血管心绞痛和外周动脉疾病等血管疾病。 | |||
T68599 |
Orphenadrine
Orphenadrine (free base) |
Sodium Channel; NMDAR; AChR | Membrane transporter/Ion channel; Neuroscience |
Orphenadrine 是一种非竞争性的 N-甲基-D-天冬氨酸(NMDA)受体拮抗剂,以浓度依赖性方式抑制克隆的 HERG 通道,在 HEK 细胞中产生0.85μM 的 IC。Orphenadrine 是中枢和外周毒蕈碱受体的拮抗剂,通过孔残基 Y652或 F656突变阻断衰减。 Orphenadrine 具有抗痉挛、镇痛和抗胆碱能活性,对在体外和体内对谷氨酸神经毒性具有保护作用。Orphenadrine 对钠离子通道具有抑制作用,可用来治疗帕金森。 | |||
T68127 |
Picenadol
LY-150720,LY150720,LY 150720 |
Others | Others |
Picenadol (LY 150720) 是N-甲基-4-苯基哌啶衍生物的外消旋混合物,具有激动剂 - 拮抗剂阿片性质。Picenadol 具有中枢镇痛活性。 | |||
T8833 |
2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid
|
Others | Others |
2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid 可用于合成多种有机化合物。 | |||
T5963 |
Menadione bisulfite sodium
Sodium menadione bisulfite,亚硫酸氢钠甲萘醌,Menadione sodium bisulfite,Vitamin K3 sodium bisulfite |
Others | Others |
Menadione bisulfite sodium (Vitamin K3 sodium bisulfite) 是可以诱导急性氧化应激的试剂,可用作植物防御活化剂,具有抵抗病菌的作用。 | |||
T1308 |
Orphenadrine hydrochloride
Mebedrol,Mephenamin,盐酸邻甲苯海拉明 |
Sodium Channel; NMDAR; Norepinephrine; iGluR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience |
Orphenadrine hydrochloride (Mephenamin) 是一种非竞争性的NMDA 受体拮抗剂, Ki=6.0 ± 0.7 μM。 | |||
T22694 |
CRANAD 2
|
Others | Others |
CRANAD 2 是一种特异性近红外 (NIR) 荧光探针,可用于检测 Aβ 斑块。它可透过血脑屏障,且对 Aβ 聚集体有高亲和性,其 Kd=38 nM。 | |||
T12005 |
meta-Fexofenadine
meta-MDL-16455,meta-Terfenadine carboxylate,Fexofenadine impurity B |
Drug Metabolite | Metabolism |
meta-Fexofenadine (meta-MDL-16455) 是 Fexofenadine 的异构体。 | |||
T21390 |
Fexofenadine
Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Fexofenadine (Carboxyterfenadine) 是一种抗组胺药物,用于治疗过敏症状,如鼻塞、花粉热和荨麻疹。与第一代抗组胺药相比,它通过血脑屏障并引起镇静的能力较差。 | |||
T2644 |
(E)-Daporinad
Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈 |
NAMPT; Transferase; Autophagy | Autophagy; Metabolism |
(E)-Daporinad (FK866) 是一种烟酰胺磷酸核糖基转移酶的小分子抑制剂,具有潜在的抗肿瘤和抗血管生成活性,IC50为 0.09 nM。 | |||
T1470 |
Fexofenadine hydrochloride
Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,盐酸非索非那定,Telfast,Fexofenadine HCl,Allegra,MDL 16455A |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) 是一种抗组胺药,用于治疗过敏性鼻炎、血管性水肿和慢性荨麻疹。 | |||
T9430 |
Venadaparib
NOV140101,IDX-1197 |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Venadaparib (NOV140101) 是一种选择性和具有口服活性的 PARP 抑制剂,对 PARP1和 PARP2的 IC50分别为 1.4 和 1.0 nM。它可防止 DNA 单链断裂 (SSB) 的修复,可研究实体瘤。 | |||
T67826 |
Alalevonadifloxacin
|
DNA gyrase; Topoisomerase; Antibacterial | DNA Damage/DNA Repair; Microbiology/Virology |
Alalevonadifloxacin 是一种DNA 回旋酶和DNA 拓扑异构酶抑制剂,是一种喹诺酮类针对Mrsa 的新型抗菌化合物。Alalevonadifloxacin 对治疗细菌性革兰氏阳性、革兰氏阴性和厌氧性感染有潜在作用。 | |||
T5015 |
Gonadorelin Acetate (33515-09-2 free base)
醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate |
Reductase | Endocrinology/Hormones; Metabolism |
Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) 是下丘脑神经肽,在控制生殖功能中起关键作用。 | |||
T26254 |
Teglarinad chloride
GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride |
NAMPT | Metabolism |
Teglarinad chloride (GMX-1777 chloride) 是一种有效的 NAMPT 的抑制剂,是 GMX1778 的前体。Teglarinad chloride 具有抗肿瘤活性,通过干扰 DNA 修复和抑制血管生成来发挥作用。 | |||
T1266 |
Terfenadine
(±)-Terfenadine,特非那定,MDL-991 |
Apoptosis; Potassium Channel; 5-HT Receptor; Caspase; Na+/Ca2+ Exchanger; HER; AChR; Histamine Receptor | Angiogenesis; Apoptosis; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Terfenadine ((±)-Terfenadine) 是一种hERG 开放通道抑制剂,IC50为 204 nM。它也是一种 H1 组胺受体拮抗剂,通过调节Ca2+稳态在黑素瘤细胞中起到有效的细胞凋亡诱导作用。 Terfenadine 诱导 ROS 依赖性细胞凋亡,同时激活Caspase-4,-2,-9。 | |||
T77092 |
Nadecnemab
REGN-5069 |
Others | Others |
Nadecnemab 是一种靶向胶质细胞源性神经营养因子家族受体 GFRA3 的 IgG4κ 抗体。Nadecnemab 可用于膝骨关节炎和神经系统疾病。 | |||
T31091 |
CRANAD-28
CRANAD28 |
Others | Others |
CRANAD-28 是一种血脑屏障(BBB)穿透型双光子成像探头,能够显示淀粉样蛋白斑块,可以标记斑块和脑淀粉样血管病。 | |||
T6618 |
Orphenadrine Citrate
Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君 |
AChR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Orphenadrine Citrate (Flexon) 是NMDA 受体拮抗剂,Ki 为6.0μM,还是HERG 钾离子通道阻断剂。它是一种骨骼肌松弛剂,它作用于中枢神经系统以产生肌肉松弛作用。 | |||
T1470L |
Fexofenadine hydrochloride
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Fexofenadine hydrochloride 是 terfenadine 的羧化代谢衍生物和长效选择性组胺 H1 受体拮抗剂,具有抗组胺活性。 | |||
T22276 |
Bis(maltolato)oxovanadium(IV)
双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) |
Phosphatase; Others | Metabolism; Others |
Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂,也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA,PTP1B,HPTPβ和SHP2的IC50分别为 126 nM,109 nM,26 nM 和 201 nM。 | |||
T7092 |
NADPH tetrasodium salt
|
Others; Ferroptosis; Endogenous Metabolite | Apoptosis; Metabolism; Others |
NADPH tetrasodium salt 是电子受体烟酰胺腺嘌呤二核苷酸磷酸的还原形式,在各种生物反应中充当电子供体。NADPH tetrasodium salt 也是一种内源性铁死亡抑制剂。 | |||
T36066 |
NADP+ (sodium salt hydrate)
|
Others | Others |
NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling. For example, binding of NADP+ to β-subunits of Kv channels activates ion transport, whereas NADPH stabilizes channel inactivation. NADP+ is biosynth... | |||
T9097 |
Guanadrel
|
Others | Others |
Guanadrel 是一种抗高血压药。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1609 |
NAD+
烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD |
NADPH; Endogenous Metabolite | Metabolism |
NAD+ (β-Nicotinamide Adenine Dinucleotide) 是一种转递氢离子的辅酶,参与细胞中的氧化还原反应。NAD+ 参与糖酵解、柠檬酸循环、脂肪酸氧化等。NAD+ 接受来自其他分子的电子形成 NADH,然后又作为还原剂来给电子。 | |||
TN2252 |
Syrosingopine
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Syrosingopine 是 MCT1和 MCT4双重抑制剂,对 MCT4 的效力高 60 倍,可防止乳酸和 H+ 流出。它是可口服抗高血压药物,联合二甲双胍具有研究癌症疾病的潜力。 | |||
T13795 |
Nicotinamide riboside
|
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Nicotinamide riboside 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。 | |||
T6220 |
Nicotinamide riboside chloride
烟酰胺核糖氯酸盐,烟酰胺核苷 |
Sirtuin; Endogenous Metabolite | Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism |
Nicotinamide riboside Chloride 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。 | |||
T4721 |
β-Nicotinamide mononucleotide
NMN,β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸 |
Others; Endogenous Metabolite | Metabolism; Others |
β-nicotinamide mononucleotide 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物。β-nicotinamide mononucleotide的作用包括其在细胞生化功能、心脏保护、糖尿病、肥胖相关并发症和阿尔茨海默病中的作用。 | |||
T8150 |
Nudifloramide
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺 |
PARP; Endogenous Metabolite | Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism |
Nudifloramide 是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的一种最终产物,可显著抑制PARP-1活性。 | |||
T0449 |
Menadione
维生素K3,Vitamin K3,甲萘醌 |
Thrombin; Endogenous Metabolite | Metabolism; Proteases/Proteasome |
Menadione (Vitamin K3) 是合成的萘醌,能够在体内转化成活性维生素 K2。 | |||
TN6754 |
1-Nonadecanol
|
Others | Others |
1-Nonadecanol 是一种 Heracleum thomsonii 的超临界二氧化碳精油的成分,也是 Neotinea ustulata 的重要香气化合物。 | |||
T5283 |
NADH disodium salt
Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠 |
Others; Endogenous Metabolite | Metabolism; Others |
NADH disodium salt hydrate是氧化还原酶的辅酶。 NADH在分解代谢过程中起到再生电子供体的作用,包括糖酵解,柠檬酸循环和β-氧化。 | |||
TN7148 |
Mukanadin C
7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one |
Others | Others |
Mukanadin C (7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one) 是一种海洋来源的天然产物,存在于 Stylissa carteri。 | |||
T8067 |
Methyl Nonadecanoate
Nonadecanoic Acid methyl ester,正十九酸甲酯 |
Others | Others |
Methyl Nonadecanoate (Nonadecanoic Acid methyl ester)是一种内标物,能够用于生物柴油中脂肪酸甲酯含量的测定。 | |||
T4448 |
NADP
|
||
NADP,也称为烟酰胺腺嘌呤二核苷酸磷酸,是各种代谢过程中电子转移所必需的重要氧化还原辅因子。 它在促进细胞能量产生和维持细胞内氧化还原平衡方面发挥着关键作用。 | |||
T8070 |
Nonadecanoic acid
|
Others | Others |
Nonadecanoic acid 是19 C长的饱和脂肪酸,是白蚁防御时分泌的主要物质。 | |||
T3373 |
Columbianadin
Zosimin,2-Butenoic acid,二氢欧山芹醇当归酸酯 |
Apoptosis | Apoptosis |
Columbianadin (Zosimin) 是来自当归的根的主要生物活性成分之一,是一种天然香豆素,具有抗炎和抗癌作用。 | |||
T22446 |
NADP disodium salt
Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐 |
Others | Others |
NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子,是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子,可以被交替氧化 (NADP+) 和还原 (NADPH)。 | |||
T8271 |
10Z-Nonadecenoic acid
|
Endogenous Metabolite | Metabolism |
10Z-Nonadecenoic acid 是一种长链脂肪酸,具有抗肿瘤特性。 | |||
TN2916 |
3-Acetoxy-4,7(11)-cadinadien-8-one
|
Others | Others |
3-Acetoxy-4,7(11)-cadinadien-8-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2916,CAS号为 104975-02-2。 | |||
T75459 |
Canadensolide
|
Others | Others |
Canadensolide 是一种 Penicillium canadense 的抗真菌代谢产物。 | |||
TN4200 |
Hennadiol
|
Others | Others |
Hennadiol是一种天然产物,属于大戟科野桐属,其产品编号为 TN4200,CAS号为 20065-99-0。Hennadiol可用作对照参考。 | |||
TN3308 |
9(11),12-Oleanadien-3-ol
|
Others | Others |
9(11),12-Oleanadien-3-ol is a natural product from Euonymus maackii. | |||
TN3253 |
7alpha-Hydroxy-4,11-cadinadiene-3,8-dione
|
Others | Others |
7alpha-Hydroxy-4,11-cadinadiene-3,8-dione 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3253,CAS号为 1423809-64-6。 | |||
TN3574 |
Canadine
|
P450 | Metabolism |
Canadine has antioxidant activity with low-toxic effect. | |||
TN3108 |
5-Epicanadensene
|
Others | Others |
5-Epicanadensene is a natural product from Taxus sumatrana. | |||
TN3129 |
5-Nonadecylresorcinol
|
Others | Others |
5-Nonadecylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells. | |||
TN7037 |
(Z)-9-nonadecene
9-Nonadecene |
Others | Others |
(Z)-9-nonadecene (9-Nonadecene) 首次在 T. melanocephalum 中被发现。它是下颌腺中的主要成分,而虹膜在尾腺中产生。 | |||
TQ0190 |
D-Xylulose
|
Others; Endogenous Metabolite | Metabolism; Others |
D-xylulose 通过葡萄糖醛酸途径中的酶 NAD+ 连接的木糖醇脱氢酶从木糖醇转化,葡萄糖醛酸途径是哺乳动物中重要的木糖醇处理代谢途径。 | |||
T0064 |
Adenine
Vitamin B4,腺嘌呤,6-Aminopurine |
DNA/RNA Synthesis; Endogenous Metabolite; AChR | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Neuroscience |
Adenine (6-Aminopurine) 是一种嘌呤衍生物,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
T0934 |
Nicotinamide
Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP |
Sirtuin; Endogenous Metabolite | Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism |
Nicotinamide 是维生素 B3 的吡啶核苷形式,可作为烟酰胺腺嘌呤二核苷酸或 NAD+ 的前体,可通过膳食摄入来补充,能预防或治疗黑舌病和糙皮病。 | |||
T0617 |
Nicotinamide N-oxide
Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide |
c-Myc; Endogenous Metabolite; CXCR; Drug Metabolite | Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; Immunology/Inflammation; Metabolism |
Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物,是高效选择性CXCR2受体拮抗剂。 | |||
T1353 |
DL-Mevalonolactone
甲瓦龙酸内酯,Mevalonolactone |
Others; Endogenous Metabolite | Metabolism; Others |
DL-Mevalonolactone ,一种人内源性代谢物,是甲羟戊酸的 δ-lactone 形式,甲羟戊酸途径的一个前体。它能够降低大脑中线粒体膜电位 (∆Ψm),Ca2+的保留能力和NAD (P) H 的含量 , 而且还诱导线粒体肿胀。DL-Mevalonolactone 诱导炎症和氧化应激反应,降低线粒体膜电位。 | |||
T4728 |
4-Acetamidobutanoic acid
N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸 |
GABA Receptor; Endogenous Metabolite; Antibacterial | Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience |
4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) 可在血液、粪便和尿液以及人体前列腺组织中找到,也存在于从酵母到人类的所有真核生物中。它是GABA 衍生物,具有抗氧化和抗菌活性。 | |||
T0879 |
Niacin
Vitamin B3,烟酸(维生素B3),Nicotinic acid |
Endogenous Metabolite; Autophagy | Autophagy; Metabolism |
Niacin (Nicotinic acid),也称为烟酸和维生素 B3,是一种水溶性必需的 B 族维生素,用于治疗维生素缺乏症以及高脂血症,血脂异常,高甘油三酯血症,并降低心肌梗塞的风险 | |||
T6369 |
Adenine hemisulfate
硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐 |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
T6225 |
Adenine hydrochloride
Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
T0809 |
Dicoumarol
Dicumarol,双羟香豆素,双香豆素 |
Dehydrogenase; NADPH; PDK | Metabolism; PI3K/Akt/mTOR signaling |
Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂,它们的IC50值分别为 0.37 和 19.42 μM。 | |||
T19477 |
Nicotinic acid mononucleotide
|
Others | Others |
Nicotinic acid mononucleotide is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. | |||
T13870 |
Riboflavine phosphate
Riboflavine 5'-phosphate |
Endogenous Metabolite | Metabolism |
Riboflavine phosphate (Flavin mononucleotide)是 Riboflavin 的衍生物。Riboflavin phosphate 可用于研究圆锥角膜、角膜扩张、不规则散光。Riboflavine phosphate 是一种高效经济的 NAD+ 回收剂。 | |||
T19253 |
Cyclic ADP-ribose
cADPR |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release | |||
T0879L |
Niacin hydrochloride
|
||
Niacin hydrochloride is a water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is needed by the body for the formation of coenzymes NAD and NADP. It possesses PELLAGRA-curative, vasodilating, and antilipemic properties. | |||
T12576 |
Pterosin B
|
SIK | PI3K/Akt/mTOR signaling |
Pterosin B 是一种广泛存在于绿色植物的叶子和芽中,是盐诱导性激酶 3 (Sik3) 信号转导抑制剂。Pterosin B 可促进 G6pc 的表达,对Ang II诱导的心肌细胞肥大具有保护作用,通过调节NAD(P)H氧化酶2/4的表达水平发挥作用。 | |||
T37687 |
Cyclic ADP-ribose ammonium
|
Others | Others |
Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum, while also facilitating extracellular influx through the opening of TRPM2 channels [1][2][3]. | |||
TN1208 |
2-Amino-3-carboxy-1,4-naphthoquinone
|
NADPH-oxidase | Immunology/Inflammation |
2-Amino-3-carboxy-1,4-naphthoquinone 是电子转移介质,可改变同型发酵乳酸菌的葡萄糖代谢,可作为双歧杆菌生长刺激剂,它通过NAD(P)H 介导的氧化作用影响双歧杆菌的终产物形态。 | |||
TN3806 |
Dehydroglyasperin C
|
ERK; IκB/IKK; p38 MAPK; TNF; NF-κB; Akt; COX; PI3K; NADPH; DNA/RNA Synthesis; Nrf2; JNK; Autophagy | Apoptosis; Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling |
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases | |||
T37911 |
cis-Resveratrol
顺式白藜芦醇,(Z)-Resveratrol |
Others | Others |
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the µM range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase ... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01106 |
NAD(P) transhydrogenase/NNT Protein, Human, Recombinant (His)
NAD(P) transhydrogenase,NNT |
Human | E. coli |
NAD(P)+transhydrogenase (NNT) is located in the inner mitochondrial membrane and catalyzes a reversible hydride transfer between NAD(H) and NADP(H) that is coupled to proton translocation between the intermembrane space and mitochondrial matrix. NNT activity has an essential role in maintaining the NADPH supply for antioxidant defense and biosynthetic pathways. Structurally, NNT is composed of three domains; domains I and III are hydrophilic and have binding sites for NAD and NADP, respectively,... | |||
TMPH-00658 |
NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His)
Riboflavin reductase [NAD(P)H],Ferrisiderophore red... |
E. coli | E. coli |
Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides. | |||
TMPH-00416 |
NAD-GDH Protein, Clostridium difficile, Recombinant (His)
gluD,NAD-specific glutamate dehydrogenase |
Peptoclostridium difficile | E. coli |
NAD-GDH Protein, Clostridium difficile, Recombinant (His) is expressed in E. coli. | |||
TMPH-00336 |
GPD2 Protein, Candida albicans, Recombinant (His)
GPD2,Glycerol-3-phosphate dehydrogenase [NAD(+)] 2 |
Candida albicans | P. pastoris (Yeast) |
GPD2 Protein, Candida albicans, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is Q59W33. | |||
TMPY-03407 |
NQO1 Protein, Human, Recombinant (His)
NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1,NMO... |
Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex... | |||
TMPJ-00462 |
NADK Protein, Human, Recombinant (His)
Poly(P)/ATP NAD Kinase,NADK,NAD K... |
Human | E. coli |
NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through phosphorylating the NAD+ coenzyme. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined. | |||
TMPY-02599 |
MDH1 Protein, Rat, Recombinant (His)
malate dehydrogenase 1, NAD (soluble) |
Rat | E. coli |
Malate dehydrogenases 1(MDH1 / MDHA) is a soluble form of malate dehydrogenases. Malate dehydrogenases (MDH) is a group of multimeric enzymes consisting of identical subunits usually organized as either dimer or tetramers with subunit molecular weights of 30-35 kDa. MDH has been isolated from different sources including archaea, eubacteria, fungi, plants, and mammals. MDH catalyzes the NAD/NADH-dependent interconversion of the substrates malate and oxaloacetate. This reaction plays a key part in... | |||
TMPH-00673 |
NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)
NAD-capped RNA hydrolase NudC,nudC,NADH py... |
E. coli | E. coli |
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. NADH pyrophosphatase Protein, E. coli O157:H7, Recombina... | |||
TMPY-02273 |
15-PGDH Protein, Mouse, Recombinant (His)
15-PGDH,AV026552,hydroxyprostaglandin dehydrogenase 15-(... |
Mouse | E. coli |
15-PGDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.6 kDa and the accession number is Q8VCC1. | |||
TMPH-00425 |
DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)
ligA,DNA ligase,Polydeoxyribonucleotide synthase [NAD |
Colwellia psychrerythraea | E. coli |
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.1 kDa and the accession number is Q47YI0. | |||
TMPH-00161 |
MDH Protein, Bacillus methanolicus, Recombinant (His)
Type 3 alcohol dehydrogenase,mdh,NAD-dependent meth... |
Bacillus methanolicus | P. pastoris (Yeast) |
Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and cannot use NADP. MDH Protein, Bacillus methanolicus, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P31005. | |||
TMPH-00475 |
DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His)
Polydeoxyribonucleotide synthase [NAD(+)],ligA,DNA ... |
Desulfotalea psychrophila | E. coli |
DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His) is expressed in E. coli. | |||
TMPH-00432 |
Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc)
Diphtheria toxin,DT,NAD(+)--diphthamide ADP-ribosyl... |
Corynephage omega | E. coli |
Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02797 |
NQO1 Protein, Mouse, Recombinant (His)
Quinone reductase 1,NAD(P)H dehydrogenase [quinone]... |
Mouse | P. pastoris (Yeast) |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q64669. | |||
TMPH-03168 |
Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)
NAD(+)--diphthamide ADP-ribosyltransferase,Exotoxin... |
Pseudomonas aeruginosa | E. coli |
An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38. Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 39.9 kDa and the accession number is P11439. | |||
TMPY-01264 |
15-PGDH Protein, Human, Recombinant (His)
PGDH1,hydroxyprostaglandin dehydrogenase 15-(NAD),P... |
Human | E. coli |
15-PGDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.7 kDa and the accession number is P15428-1. | |||
TMPH-00162 |
MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO)
NAD-dependent methanol dehydrogenase,Type 3 alcohol... |
Bacillus methanolicus | E. coli |
Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and cannot use NADP. MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 59.9 kDa and the accession number is P31005. | |||
TMPH-01742 |
SIRT6 Protein, Human, Recombinant (GST)
Protein mono-ADP-ribosyltransferase sirtuin-6,NAD-d... |
Human | E. coli |
SIRT6 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 66.0 kDa and the accession number is Q8N6T7. | |||
TMPH-00916 |
ADH1B Protein, Human, Recombinant (His & SUMO)
ADH2,Alcohol dehydrogenase subunit beta,All-trans-retinol de... |
Human | E. coli |
Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. ADH1B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli... | |||
TMPH-00207 |
PTX S1 Protein, Bordetella pertussis, Recombinant (His)
Islet-activating protein S1,Pertussis toxin subunit 1,NA... |
Bordetella pertussis | P. pastoris (Yeast) |
S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. PTX S1 Protein, Bordetella pertussis, ... | |||
TMPH-00093 |
GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
NAD-dependent glyceraldehydephosphate dehydrogenase... |
Arabidopsis thaliana | E. coli |
GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.4 kDa and the accession number is P25858. | |||
TMPH-00417 |
4HbD Protein, Clostridium kluyveri, Recombinant (His & Myc)
GHBDH,NAD(+)-dependent 4-hydroxybutyrate dehydrogen... |
Clostridium kluyveri | E. coli |
4HbD Protein, Clostridium kluyveri, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02798 |
SIRT3 Protein, Mouse, Recombinant (His & Myc)
Regulatory protein SIR2 homolog 3,Sirt3,NAD-depende... |
Mouse | E. coli |
SIRT3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.3 kDa and the accession number is Q8R104. | |||
TMPH-02149 |
ALDH5A1 Protein, Human, Recombinant (His)
Succinate-semialdehyde dehydrogenase, mitochondrial,NAD<... |
Human | P. pastoris (Yeast) |
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). | |||
TMPH-01745 |
NOX4 Protein, Human, Recombinant (Cell-Free, His)
NOX4,Kidney oxidase-1,Renal NAD(P)H-oxidase,Kidney ... |
Human | E. coli |
NOX4 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 69.8?kDa and the accession number is Q9NPH5. | |||
TMPH-02799 |
SIRT5 Protein, Mouse, Recombinant (E. coli, His & Myc)
NAD-dependent protein deacylase sirtuin-5, mitochon... |
Mouse | E. coli |
SIRT5 Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.6 kDa and the accession number is Q8K2C6. | |||
TMPH-02800 |
SIRT5 Protein, Mouse, Recombinant (His & Myc)
Regulatory protein SIR2 homolog 5,Sirt5,NAD-depende... |
Mouse | Baculovirus Insect Cells |
SIRT5 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-00917 |
ADH4 Protein, Human, Recombinant (GST)
Alcohol dehydrogenase 4,Alcohol dehydrogenase 2,All-trans-re... |
Human | E. coli |
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones. ADH4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 67.2 kDa and the accession n... | |||
TMPH-01746 |
NOX4 Protein, Human, Recombinant (E. coli, His)
Kidney superoxide-producing NADPH oxidase,NOX4,... |
Human | E. coli |
NOX4 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is Q9NPH5. | |||
TMPH-01741 |
SARM1 Protein, Human, Recombinant (His & KSI)
Sterile alpha and Armadillo repeat protein,Sterile alpha mot... |
Human | E. coli |
SARM1 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 48.8 kDa and the accession number is Q6SZW1. | |||
TMPH-01881 |
PARP2 Protein, Human, Recombinant (GST & His)
Protein poly-ADP-ribosyltransferase PARP2,NAD(+) AD... |
Human | Baculovirus Insect Cells |
PARP2 Protein, Human, Recombinant (GST & His) is expressed in Baculovirus insect cells with N-GST and C-6xHis tag. The predicted molecular weight is 92.8 kDa and the accession number is Q9UGN5. | |||
TMPH-03192 |
NAD2 Protein, Psoroptes ovis, Recombinant (His)
NADH-ubiquinone oxidoreductase chain 2,NAD... |
Psoroptes ovis | E. coli |
N/A. NAD2 Protein, Psoroptes ovis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.7 kDa and the accession number is A0A075XDS2. | |||
TMPH-01880 |
PARP2 Protein, Human, Recombinant (His)
Protein poly-ADP-ribosyltransferase PARP2,Poly [ADP-ribose] ... |
Human | E. coli |
PARP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is Q9UGN5. | |||
TMPH-01740 |
SARM1 Protein, Human, Recombinant (His & Myc)
Tir-1 homolog,Sterile alpha and Armadillo repeat protein,Ste... |
Human | Baculovirus Insect Cells |
SARM1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 80.4 kDa and the accession number is Q6SZW1. | |||
TMPH-00844 |
HSD11B2 Protein, Human, Recombinant (His)
HSD11B2,11-beta-hydroxysteroid dehydrogenase type 2,Short ch... |
Human | P. pastoris (Yeast) |
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365. | |||
TMPH-01039 |
CBR1 Protein, Human, Recombinant (E. coli, His)
Alcohol dehydrogenase [NAD(P)+] CBR1,CBR1,20-beta-h... |
Human | E. coli |
CBR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.2?kDa and the accession number is P16152. | |||
TMPH-01040 |
CBR1 Protein, Human, Recombinant (His)
20-beta-hydroxysteroid dehydrogenase,Carbonyl reductase [ |
Human | P. pastoris (Yeast) |
CBR1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is P16152. | |||
TMPH-03060 |
NaD1 Protein, Nicotiana alata, Recombinant (His & SUMO)
D1,Flower-specific defensin,NaD1 |
Nicotiana alata | E. coli |
Plant defense peptide with antifungal activity against F.oxysporum and B.cinerea. Retards the growth of the Lepidopteran insect pests H.armigera and H.punctigera. | |||
TMPH-03421 |
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) VP7 Protein (His & Myc)
Outer capsid glycoprotein VP7 |
RV-A | E. coli |
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) VP7 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.0 kDa and the accession number is A8D8S8. | |||
TMPY-05932 |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His)
NA Protein |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0G3XQY1. | |||
TMPY-00647 |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His)
CG-α,FSH alpha,glycoprotein hormones, alpha polypeptide,FSHA... |
Human | HEK293 Cells |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.6 kDa and the accession number is P01215. | |||
TMPY-02923 |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc)
HCG,GPHa,CG-ALPHA,glycoprotein hormones, alpha polypeptide,g... |
Human | HEK293 Cells |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 36.6 kDa and the accession number is P01215. | |||
TMPH-01743 |
NADP-ME Protein, Human, Recombinant (His)
NADP-dependent malic enzyme, mitochondrial,ME3,Mali... |
Human | E. coli |
NADP-ME Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.2 kDa and the accession number is Q16798. | |||
TMPY-01495 |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H2N2 | HEK293 Cells |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is Q4ZH98. | |||
TMPY-00298 |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H2N2 | Baculovirus Insect Cells |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q4ZH98. | |||
TMPY-06517 |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His)
NA Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.64 kDa and the accession number is AKM14549. | |||
TMPH-03354 |
Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His)
Progonadoliberin-1,Gnrh1,Progonadoliberin ... |
Rat | E. coli |
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 12.2 kDa and the accession number is P07490. | |||
TMPY-04586 |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant
FSH alpha,glycoprotein hormones, alpha polypeptide,LHA,CG-AL... |
Human | HEK293 Cells |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 10.2 kDa and the accession number is P01215. | |||
TMPH-03045 |
NadA Protein, MenB, Recombinant (His)
Quinolinate synthase,nadA |
MenB | E. coli |
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | |||
TMPH-03047 |
NadA Protein, MenC, Recombinant (His)
Quinolinate synthase,nadA |
MenB | E. coli |
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. NadA Protein, MenC, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.1 kDa and the accession number is A1KVN9. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12167 |
Nadolol-d9
纳多洛尔 D9,SQ-11725 D9,Nadolol D9 |
Others | Others |
Nadolol D9 is the deuterium labeled Nadolol is a blocker of non-selective beta. | |||
T11276 |
Fexofenadine-d6
MDL-16455-d6,Terfenadine carboxylate-d6 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Fexofenadine-d6 (MDL-16455-d6) 是 Fexofenadine 的氘代物,可用做检测人血浆中非索非那定浓度的内标。 | |||
TMIJ-0317 |
Nadolol-d9 (Mixture of Diastereomers)
|
||
Nadolol-d9 (Mixture of Diastereomers) 是 Nadolol 的氘代化合物。Nadolol 的 CAS 号为 42200-33-9。Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。 | |||
TMID-0065 |
Adenine-2-d1
|
||
Adenine-2-d1 是 Adenine 的氘代化合物。Adenine 的 CAS 号为 73-24-5。Adenine 是一种嘌呤衍生物,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
T69395 |
Nicotinamide-d4
|
||
Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl... |