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Leptomycin B (LMB) 是一种抗真菌抗生素,可阻断真核细胞周期,抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。
Leptomycin B (LMB) 是一种抗真菌抗生素,可阻断真核细胞周期,抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,780 | In stock | |
5 mg | ¥ 5,470 | In stock | |
10 mg | ¥ 7,460 | In stock | |
25 mg | ¥ 11,300 | In stock | |
50 mg | ¥ 15,000 | In stock | |
1 mL x 10 mM (in DMSO) | ¥ 2,060 | In stock |
产品描述 | Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. |
别名 | 来普霉素B, LMB, CI 940 |
分子量 | 540.73 |
分子式 | C33H48O6 |
CAS No. | 87081-35-4 |
Smiles | CC\C(\C=C\[C@H]1OC(=O)C=C[C@@H]1C)=C\[C@H](C)C\C=C\C(\C)=C\[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C\C(C)=C\C(O)=O |
密度 | 1.072 g/cm3 (Predicted) |
存储 | store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 70 mg/mL (129.45 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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