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Search Results for " triglycerides "
Targets Recommended: Others

30

抑制剂 & 化合物

16

天然产物

4

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T14933 Cetaben

Others Others
Cetaben 是不依赖 PPARα 的过氧化物酶体增殖物。它可有效降低胆固醇和甘油三酸酯的浓度,是一种非纤维化降血脂药。
T9766 GW590735

PPAR DNA Damage/DNA Repair; Metabolism
GW590735 是一种有效的选择性 PPARα 激动剂,对 PPARα 的 EC50 为 4 nM,比 PPARδ 和 PPARγ 的选择性至少高 500 倍。 GW590735 可用于血脂异常研究。
T2499 Torcetrapib

CP-529414,托彻普

CETP Metabolism
是胆固醇酯转移蛋白 (CETP) 选择性抑制剂。根据人血浆的抑制曲线,Torcetrapib (CP-529414) 对CETP 的最有效浓度为 37 nM。
T1676 Rosuvastatin

罗伐他汀,ZD 4522,瑞舒伐他汀

Potassium Channel; HMG-CoA Reductase; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Rosuvastatin (ZD 4522) 是一种抗血脂药,可竞争性抑制羟甲基戊二酰辅酶 A 还原酶,用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,IC50为 195 nM,延迟心脏复极化,延长动作电位持续时间和校正 QT 间期间隔。
T1510 Rosuvastatin calcium

ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙

Potassium Channel; HMG-CoA Reductase; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂,具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用,还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,延迟心脏复极化,来延长动作电位持续时间和校正 QT 间期间隔。
T27691 JNJ-DGAT2-A

JNJDGAT2A

Transferase Metabolism
JNJ-DGAT2-A 是 DGAT2 的特异性抑制剂(IC50 = 0.14 μM),可用于甘油三酯合成的研究。
T19861 Niceritrol

Perycit,Cardiolipol,戊四烟酯,Bufor

Others Others
Niceritrol (Cardiolipol) 是一种烟酸酯,可降低总血浆以及 VLD 和 LD 脂蛋白部分中的胆固醇和甘油三酯。
T9106 E1231

Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair
E1231 是 SIRT1 的激活剂。 E1231 通过增强 ABCA1 表达来防止实验性动脉粥样硬化并降低血浆胆固醇和甘油三酯。
T0841 Bezafibrate

BM15075,苯扎贝特

PPAR DNA Damage/DNA Repair; Metabolism
Bezafibrate (BM15075) 是一种降血脂剂,是PPAR 的激动剂,对人以及鼠PPARα、PPARγ和PPARδ的EC50分别为 50、60和20 μM, 以及 90、55 和110 μM。
T15821 LY518674

LY-674

PPAR DNA Damage/DNA Repair; Metabolism
LY518674 (LY-674) 是一种高效、选择性的 PPARα 激动剂,对人 PPARα 作用的 EC50 值为 42 nM。LY518674 能降低甘油三酸酯,增加 HDL-C,可用于研究动脉粥样硬化。
T19864 Xenalipin

BW 207U

Others Others
Xenalipin (BW 207U) 具有降血脂作用。它可以降低大鼠的血液胆固醇和甘油三酯。
T16018 MB-07811

VK-2809

Thyroid hormone receptor(THR) Endocrinology/Hormones
MB-07811 (VK-2809) 是 MB07344 的一种口服活性 HepDirect 前药,具有降低胆固醇和甘油三酯的活性。 MB-07811 是肝脏靶向甲状腺激素受体-β 的激动剂。
T19057 Solvent Blue 35

Sudan Blue II,溶剂蓝35,溶剂蓝 35,Oil Blue 35

Others Others
Solvent Blue 35 (Sudan Blue II) 是一种可用于着色醇类和烃基溶剂的染料。它能够作用于染色动物组织中的甘油三酯。
T15549 Icosabutate

NST-4016,PRC-4016

Others Others
Icosabutate (NST-4016) 是一种具有口服活性的二十碳五烯酸的衍生物,可抑制 NASH 的肝脏炎症和纤维化,可改善他汀类药物治疗的残留高甘油三酯血症患者的心血管风险状况,降低甘油三脂,可用于研究肝纤维化和动脉粥样硬化。
T6267 Lomitapide

AEGR-733,洛美他派,BMS-201038

CETP Metabolism
Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂,体内试验的IC50值为8 nM。
T11386L Gemcabene

PD-72953

Others Others
Gemcabene (PD-72953) 是一种具有抗炎活性的降脂剂。 Gemcabene 降低低密度脂蛋白胆固醇和甘油三酯,提高高密度脂蛋白胆固醇,并降低促炎急性期蛋白、C 反应蛋白。
T4681 T863

DGAT-3,DGAT-1 inhibitor

Acyltransferase; Transferase Metabolism
T863 (DGAT-3) 是口服有效的二酰基甘油酰基转移酶1 选择性抑制剂。T863结合DGAT1的酰基辅酶A 结合位点,抑制三酰甘油在细胞内的合成。
T26345 YM-53601

YM53601

Others Others
YM-53601 is a squalene synthase activity inhibitor that acts by lowering cholesterol as well as triglycerides.
T85105 1,3-Dilinoelaidoyl Glycerol

DG(18:2/0:0/18:2),1,3-Dilinoelaidin

Others Others
1,3-Dilinoleoyl glycerol, a diacylglycerol, incorporates linoelaidic acid at both the sn-1 and sn-3 positions. This compound emerges from the collision-induced decomposition of synthetic linoleic ammoniated triglycerides.
T24261 KHG26693

KHG-26693,KHG 26693

Others Others
KHG26693 is an anti-inflammatory and antioxidant agent that acts by significantly decreasing blood glucose, triglycerides, cholesterol and increased insulin.
T19432 Mono-and diglycerides

Others Others
Mono-and diglycerides is formed by triglycerides .
T33660 Nicofibrate hydrochloride

Nicofibrate HCl,Arterium V,Nicofibrate hydrochloride,

Others Others
Nicofibrate hydrochloride is a biochemical which may cause a significant reduction in plasma cholesterol and triglycerides and bring lipoprotein levels to normal. Nicofibrate HCl may also lead to a significant drop in plasma prothrombinic activity.
T11386 Gemcabene calcium

PD-72953 calcium

Others Others
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).
T39303 CP-346086

Others Others
CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces plasma levels of cholesterol and triglycerides when administered in vivo.
T74757 Didocosahexaenoin

Others Others
Didocosahexaenoin 是一种 omega-3 衍生物,是 DHA 的甘油二酯,可由 DHA 甘油三酯合成。Didocosahexaenoin 导致线粒体膜电位显着丧失并诱导 ROS 产生。Didocosahexaenoin 诱导细胞凋亡。Didocosahexaenoin 在人前列腺癌细胞中诱导比 DHA 更强的细胞毒性。
T69408 GW590735 sodium

Others Others
GW590735 is a potent and selective agonist of PPARα with an EC50 value of 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivity versus PPARγ and PPARδ. GW590735 significantly increased HDL cholesterol, decreased LDL and VLDL cholesterol, and significantly reduced triglycerides. Maximal increases in HDL cholesterol were 37%, 53%, and 84% with fenofibrate, torcetrapib, and GW590735, respectively.
T36567 DPPP

DPPP is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O). Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidylethanolamine, triglycerides, and cholesteryl esters have been measured by HPLC with a post column detection system using DPPP. DPPP has also been used as a fluorescent probe for the detection of low density lipoprotein and cellular oxidation. Fluorescence of DPPP-O can be monitor ...
T36765 Palmitelaidic Acid methyl ester

Others Others
Palmitoleic acid is a common constituent of the triglycerides of human adipose tissue. Palmitoleic acid-based diets raise low-density lipoprotein cholesterol and diminish high-density lipoprotein cholesterol, even when dietary intake of cholesterol is maintained at a low level. Palmitelaidic acid is the trans isomer of the 16:1 fatty acid palmitoleic acid. While its effects on cholesterol levels are poorly studied, palmitelaidic acid can have very different effects from those of palmitoleic acid...
T35800 MD001

Others Others
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. It increases transcriptional activity of PPARα and PPARγ in a cell-based luciferase reporter assay when used at a concentration of 10 μM. MD001 (10 μM) increases expression of PPARα, PPARγ, and retinoid X receptor (RXR), as well as PPARα and PPARγ target genes, in HepG2 cells. It...
T37522 Teneligliptin

Others Others
Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneligliptin (MP-513) inhibits all these DPP-4 enzymes in a concentration-dependent manner. The IC50s of Teneligliptin (MP-513) for rhDPP-4, human plasma, and rat plasma are 0.889, 1.75, and 1.35 nM, respectively. A study of enzyme inhibition kinetics is conducted for Teneligliptin (M...

化合物

Cetaben
Cat.No: T14933
Synonym:
Target: Others
GW590735
Cat.No: T9766
Synonym:
Target: PPAR
Torcetrapib
Cat.No: T2499
Synonym: CP-529414,托彻普
Target: CETP
Rosuvastatin
Cat.No: T1676
Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
Rosuvastatin calcium
Cat.No: T1510
Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
JNJ-DGAT2-A
Cat.No: T27691
Synonym: JNJDGAT2A
Target: Transferase
Niceritrol
Cat.No: T19861
Synonym: Perycit,Cardiolipol,戊四烟酯,Bufor
Target: Others
E1231
Cat.No: T9106
Synonym:
Target: Sirtuin
Bezafibrate
Cat.No: T0841
Synonym: BM15075,苯扎贝特
Target: PPAR
LY518674
Cat.No: T15821
Synonym: LY-674
Target: PPAR
Xenalipin
Cat.No: T19864
Synonym: BW 207U
Target: Others
MB-07811
Cat.No: T16018
Synonym: VK-2809
Target: Thyroid hormone receptor(THR)
Solvent Blue 35
Cat.No: T19057
Synonym: Sudan Blue II,溶剂蓝35,溶剂蓝 35,Oil Blue 35
Target: Others
Icosabutate
Cat.No: T15549
Synonym: NST-4016,PRC-4016
Target: Others
Lomitapide
Cat.No: T6267
Synonym: AEGR-733,洛美他派,BMS-201038
Target: CETP
Gemcabene
Cat.No: T11386L
Synonym: PD-72953
Target: Others
T863
Cat.No: T4681
Synonym: DGAT-3,DGAT-1 inhibitor
Target: Acyltransferase, Transferase
YM-53601
Cat.No: T26345
Synonym: YM53601
Target: Others
1,3-Dilinoelaidoyl Glycerol
Cat.No: T85105
Synonym: DG(18:2/0:0/18:2),1,3-Dilinoelaidin
Target: Others
KHG26693
Cat.No: T24261
Synonym: KHG-26693,KHG 26693
Target: Others
Mono-and diglycerides
Cat.No: T19432
Synonym:
Target: Others
Nicofibrate hydrochloride
Cat.No: T33660
Synonym: Nicofibrate HCl,Arterium V,Nicofibrate hydrochloride,
Target: Others
Gemcabene calcium
Cat.No: T11386
Synonym: PD-72953 calcium
Target: Others
CP-346086
Cat.No: T39303
Synonym:
Target: Others
Didocosahexaenoin
Cat.No: T74757
Synonym:
Target: Others
GW590735 sodium
Cat.No: T69408
Synonym:
Target: Others
DPPP
Cat.No: T36567
Synonym:
Target:
Palmitelaidic Acid methyl ester
Cat.No: T36765
Synonym:
Target: Others
MD001
Cat.No: T35800
Synonym:
Target: Others
Teneligliptin
Cat.No: T37522
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T14862 Caprylic/Capric Triglyceride

Others Others
Caprylic/Capric Triglyceride 是一种从分离的植物油中提取的甘油三酯和酯,以及从椰子油和棕榈仁油中提取的脂肪酸。它具有良好的氧化稳定性,可用作食品添加剂及用于化妆品。
T10020 1-Methyluric acid

1-Methyl-2,6,8-trihydroxypurine,1-Methylurate

Endogenous Metabolite Metabolism
1-Methyluric acid (1-Methylurate) 作用于膀胱粘膜并增加胰岛素、甘油三酯、胆固醇和血糖的水平。
T21383 D-Thyroxine

Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine

Others Others
D-Thyroxine (Dextroxin) 是一种甲状腺激素,对 TSH 的分泌具有抑制作用,可用于研究高胆固醇血症。
TN2364 Sudan IV

苏丹红Ⅳ,Solvent Red 24,C.I. 26105

Others Others
Sudan IV (Solvent Red 24) 是脂溶性重氮染料,可用于冰冻或石蜡切片上,能够将脂类、甘油三酯和脂蛋白染色。
T3771 Methyl protodioscin

山药,Smilax saponin B,NSC-698790

Apoptosis Apoptosis
Methyl protodioscin (Smilax saponin B) 是一种甾二糖苷,能诱导细胞周期阻滞,具有抗肿瘤活性。
T5242 Triarachidin

Triarachin,1,2,3-Trieicosanoyl Glycerol,Glycerol Trieicosanoate,三花生精

Others; Endogenous Metabolite Metabolism; Others
Triarachidin (1,2,3-Trieicosanoyl Glycerol) 是内源性代谢产物的一种。
T3859 Isomucronulatol

7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚

Others Others
Isomucronulatol 是一种黄酮类化合物,分离自A. membranaceus根。它在体外对 LPS 刺激产生的 IL-12 p40 有抑制作用,具有潜在的抗炎作用。
T75636 (E/Z)-Squalene

(E/Z)-Super Squalene,(E/Z)-AddaVax

Others Others
(E/Z)-Squalen 调节细胞内活性氧化物质 (ROS) 的产生,并呈浓度和时间依赖性引起细胞凋亡和坏死 。(E/Z)-Squalene ((E/Z)-AddaVax) 在肝脏中积累并降低肝脏胆固醇和甘油三酯。
T2P2919 (2S,3R,4S)-4-Hydroxyisoleucine

(4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine

PI3K PI3K/Akt/mTOR signaling
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分,具有抗糖尿病、抗糖尿病肾病的作用。
T5227 Tricaprin

Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate,甘油三癸酸酯,三癸酸甘油酯

Others; Endogenous Metabolite Metabolism; Others
Glycerol Tridecanoate 是癸酸的一种口服具有活性前体 (DA precursor),能够被水解为癸酸。它是中链甘油三酸酯 (MCT) 的主要成分,具有抗雄激素和抗高血糖特性。 它能够用做食品,药品,化妆品中的添加剂。
T1664 Meglutol

Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托

Endogenous Metabolite; HMG-CoA Reductase; Autophagy Autophagy; Metabolism
Meglutol (3-Hydroxy-3-methylglutaric acid) 是一种抗血脂剂,可降低胆固醇、甘油三酯、血清 β-脂蛋白和磷脂。它抑制胆固醇生物合成中的限速酶羟甲基戊二酰辅酶 A 还原酶的活性。
T5074 Cholesteryl palmitate

Others; Endogenous Metabolite Metabolism; Others
Cholesteryl palmitate 是一种慢性间质性肺炎的有用预后生物标志物。
T3123 Allicin

ERK; IL Receptor; Others; IκB/IKK; p38 MAPK; TNF; ROS; Caspase; Antifection Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; Others; Proteases/Proteasome
Allicin 具有抗氧化、杀菌、抗癌、抗炎活性,对肠上皮细胞具有抑制性免疫调节作用。 Allicin 能显着抑制胰岛素诱导的血管平滑肌细胞的增殖和迁移,这可能与抑制 ERK 信号通路的激活有关。 Allicin 有利于降低高胆固醇血症大鼠的血液胆固醇、甘油三酯水平和收缩压,它可能有益于影响动脉粥样硬化的两个危险因素——高脂血症和高血压。
T4776 Glycerol

Glycerin,甘油

Endogenous Metabolite Metabolism
Glycerol 是甘油三酯(即脂肪和油)和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
TN4584 Morolic acid

IL Receptor; COX; HIV Protease Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro
TN4585 Moronic acid

HIV Protease; Antifection; HSV Microbiology/Virology; Proteases/Proteasome
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an...

天然产物

Caprylic/Capric Triglyceride
Cat.No: T14862
Synonym:
Target: Others
1-Methyluric acid
Cat.No: T10020
Synonym: 1-Methyl-2,6,8-trihydroxypurine,1-Methylurate
Target: Endogenous Metabolite
D-Thyroxine
Cat.No: T21383
Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine
Target: Others
Sudan IV
Cat.No: TN2364
Synonym: 苏丹红Ⅳ,Solvent Red 24,C.I. 26105
Target: Others
Methyl protodioscin
Cat.No: T3771
Synonym: 山药,Smilax saponin B,NSC-698790
Target: Apoptosis
Triarachidin
Cat.No: T5242
Synonym: Triarachin,1,2,3-Trieicosanoyl Glycerol,Glycerol Trieicosanoate,三花生精
Target: Others, Endogenous Metabolite
Isomucronulatol
Cat.No: T3859
Synonym: 7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚
Target: Others
(E/Z)-Squalene
Cat.No: T75636
Synonym: (E/Z)-Super Squalene,(E/Z)-AddaVax
Target: Others
(2S,3R,4S)-4-Hydroxyisoleucine
Cat.No: T2P2919
Synonym: (4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine
Target: PI3K
Tricaprin
Cat.No: T5227
Synonym: Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate,甘油三癸酸酯,三癸酸甘油酯
Target: Others, Endogenous Metabolite
Meglutol
Cat.No: T1664
Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托
Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy
Cholesteryl palmitate
Cat.No: T5074
Synonym:
Target: Others, Endogenous Metabolite
Allicin
Cat.No: T3123
Synonym:
Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection
Glycerol
Cat.No: T4776
Synonym: Glycerin,甘油
Target: Endogenous Metabolite
Morolic acid
Cat.No: TN4584
Synonym:
Target: IL Receptor, COX, HIV Protease
Moronic acid
Cat.No: TN4585
Synonym:
Target: HIV Protease, Antifection, HSV
Cat. No. Product Name Species Expression System
TMPH-00491 PNLIPRP1 Protein, Canine, Recombinant (His)

Inactive pancreatic lipase-related protein 1,PNLIPRP1

Canine P. pastoris (Yeast)
May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro). PNLIPRP1 Protein, Canine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.7 kDa and the accession number is P06857.
TMPH-00492 PNLIPRP1 Protein, Canine, Recombinant (His & SUMO)

Inactive pancreatic lipase-related protein 1,PNLIPRP1

Canine E. coli
May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro). PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.7 kDa and the accession number is P06857.
TMPJ-00601 Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)

Apolipoprotein C2,Apolipoprotein C-II,APC2 and APOC2

Human E. coli
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoprot...
TMPJ-00286 ANGPTL3 Protein, Human, Recombinant (hFc)

ANGPTL3,ANGPT5,Angiopoietin-related protein 3,ANG-5,Angiopoi...

Human HEK293 Cells
Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits ...

重组蛋白

PNLIPRP1 Protein, Canine, Recombinant (His)
Cat.No: TMPH-00491
Species: Canine
Expression System: P. pastoris (Yeast)
PNLIPRP1 Protein, Canine, Recombinant (His & SUMO)
Cat.No: TMPH-00492
Species: Canine
Expression System: E. coli
Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00601
Species: Human
Expression System: E. coli
ANGPTL3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00286
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0296 Bezafibrate-d6 (dimethyl-d6)

Bezafibrate-d6 (dimethyl-d6) 是 Bezafibrate 的氘代化合物。Bezafibrate 的 CAS 号为 41859-67-0。Bezafibrate 是一种降血脂剂,是PPAR的激动剂,对人以及鼠PPARα、PPARγ和PPARδ的EC50分别为 50、60和20 μM, 以及 90、55 和110 μM。

同位素标记化合物

Bezafibrate-d6 (dimethyl-d6)
Cat.No: TMIJ-0296
Synonym:
Target:
TargetMol Loading
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