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Cat. No. | Product Name | Target | Signaling Pathways |
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TP2204L |
CCK Octapeptide, non-sulfated acetate
CCK Octapeptide, non-sulfated acetate(25679-24-7 Free base) |
cholecystokinin | GPCR/G Protein |
CCK Octapeptide, non-sulfated acetate 是一种合成的胆囊收缩素脱硫酸肽。 | |||
T37205 |
CCK (26-31) (sulfated)
|
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CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% when used at a concentration of 0.1 mM. | |||
T37203 |
CCK (26-30) (sulfated)
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||
CCK (26-30) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% when used at a concentration of 0.1 mM. | |||
T38645 |
Acetyl-Hirudin (54-65) (sulfated)
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Acetyl-Hirudin (54-65) (sulfated) directly binds to thrombin-rHCII(L444R) and hinders the interaction between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin, which stabilizes the complex. | |||
T37204 |
CCK (26-31) (non-sulfated)
|
||
CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. | |||
T37206 |
CCK (27-33) (non-sulfated)
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CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in m... | |||
T35583 |
Hirudin (54-65; non-sulfated) (trifluoroacetate salt)
|
Others | Others |
Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2 1.Niehrs, C., Huttner, W.B., Carvallo, D., et al.Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferasesJ. Biol. Chem.265(16)9314-9318(1990) 2.Payne, M.H., Krste... | |||
TP2204 |
Cholecystokinin Octapeptide, desulfated
CCK Octapeptide, non-sulfated |
Others | Others |
Non-sulfated form of the C-terminal octapeptide of CCK | |||
T83485 |
[Thr28, Nle31]-Cholecystokinin (25-33), sulfated
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[Thr28, Nle31]-Cholecystokinin (25-33) 是一种具备CCK8所有生物活性的胆囊收缩素 (CCK) 类似物,表现出食欲抑制功效。它在胃肠道系统和中枢神经系统中担任激素和神经递质角色。此肽通过 Thr28 和 Nle31 的特殊替代,展现出在酸性条件下的高稳定性,并能抵抗空气氧化(防止蛋氨酸受损)。其主要构象特征为以Thr4为核心的γ转角和Gly5分隔的C末端螺旋片段。 | |||
T80119 |
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
|
Thrombin | Proteases/Proteasome |
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) 是一种具有高亲和力的Hirugen类肽,其与凝血酶的KD值小于100 nM。作为抗血栓剂,它能有效抑制凝血酶诱导的纤维蛋白凝块生成,其IC50值为0.087 μM。 | |||
T39170 |
Cholecystokinin Octapeptide, desulfated TFA
CCK Octapeptide, desulfated TFA,Cholecystokinin Octapeptide, desulfated TFA |
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Cholecystokinin Octapeptide, desulfated TFA, is a synthetic octapeptide derived from Cholecystokinin (CCK) that has undergone desulfation. | |||
TP1547 |
Caerulein, desulfated
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Caerulein, desulfated is the desulfurated form of Caerulein. Caerulein is a deceptide with the same five carboxy-terminal amino acids as gastrin and cholecystatin (CCK). | |||
TP1377 |
Caerulein, desulfated TFA (20994-83-6 free base)
Caerulein, desulfated TFA |
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Caerulein, desulfated TFA is Caerulein after desulfurization.Caerulein is a deceptide with the same five carboxy-terminating amino acids as gastrin and cholecystatin (CCK).. | |||
T6531 |
Heparin sodium salt
肝素钠,Sodium heparinate,Heparin sodium |
Factor Xa; Thrombin; Autophagy | Autophagy; Metabolism; Proteases/Proteasome |
Heparin sodium salt (Sodium heparinate) 是一种抗凝血剂,可以干扰血凝过程中的多个环节。Heparin sodium salt 可以与抗凝血酶 III 可逆结合,加快凝血酶因子 IIa 和 Xa 的失活速度,从而发挥抗凝作用。 | |||
T25163 |
Bivittoside B
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Others | Others |
Bivittoside B 是一种非硫酸化的六苷类化合物,从波氏海参中提取得到,具有抗真菌活性和潜在抗肿瘤活性。 | |||
T25162 |
Bivittoside A
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Others | Others |
Bivittoside A 是一种非硫酸化的六苷类化合物,从波氏海参中提取得到,具有抗真菌活性和潜在抗肿瘤活性。 | |||
T37812 |
6-O-Sulfo-β-cyclodextrin (sodium salt)
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Others | Others |
6-O-Sulfo-β-cyclodextrin is a sulfated cyclodextrin.1It has been used for the chiral separation of nadolol racemates by capillary electrophoresis. 1.Wang, F., Dowling, T., Bicker, G., et al.Electrophoretic chiral separation of pharmaceutical compounds with multiple stereogenic centers in charged cyclodextrin mediaJ. Sep. Sci.24(5)378-384(2001) | |||
T35797 |
Lithocholic acid 3-sulfate disodium
Sulfolithocholic acid disodium |
Others | Others |
Lithocholic acid 3-sulfate disodium (Sulfolithocholic acid disodium) 可作为 RORgammat 配体,抑制 Th17 细胞分化。Lithocholic acid 3-sulfate disodium 是石胆酸(LCA)的硫酸化产物,可诱导细胞损伤。 | |||
T37004 |
Estradiol 3-sulfate 17β-Glucuronide (potassium salt)
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Others | Others |
Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com... | |||
T38283 |
Tetracosanoyl-sulfatide
C24 3'-sulfo Galactosylceramide (d18:1/24:0) |
Others | Others |
Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mo... | |||
T75518 |
Galactofucan
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Others | Others |
Galactofucan (Fucogalactan) 是一种硫酸多糖。Galactofucan 可以从棕色海藻 Saccharina longicruris 中提取,具有抗凝血、抗肿瘤、抗血栓形成、抗炎、抗病毒等特性。Galactofucan 对 HSV-1和 HSV-2具有抗病毒活性,IC50值分别为 0.76 和 1.34 µg/mL 。Galactofucan 可用于癌症和炎症的研究。 | |||
T82151 |
Hyaluronan-binding peptide, biotin labeled
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Hyaluronan-binding peptide, biotin labeled 是通过 C 端 GGGSK 残基生物素化的透明质酸结合肽,能够干预 HA 与 CD44 受体的作用,并阻碍 T 细胞增殖。 HA 在细胞外基质和细胞表面广泛表达,参与多种生物过程,包括受精、胚胎发育、伤口修复、血管新生、炎症反应和肿瘤转移。 | |||
T36132 |
3β-OH-7-Oxocholenic Acid
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Others | Others |
3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3 |1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat. Steroids 15(3), 303-326 (1970).|2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick dise... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T40416 |
D-Dimannuronic acid
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Others | Others |
D-Dimannuronic acid, derived from brown algae, is an alginate extract employed in the synthesis of sulfated polymannuronate (SPMG)-derived oligosaccharides. | |||
T38179 |
C16 3'-sulfo Galactosylceramide (d18:1/16:0)
C16 3'-sulfo Galactosylceramide (d18:1/16:0) |
Others | Others |
C16 3'-sulfo Galactosylceramide (d18:1/16:0)是硫酸盐类糖脂的一种。C16 3'-sulfo Galactosylceramide (d18:1/16:0)是在猪脑和血浆中发现的一种比较丰富的硫化物,在小鼠的整个发育过程中会有所减少。C16 3'-sulfo Galactosylceramide (d18:1/16:0)在体外可抑制视网膜神经节细胞生长。C16 3'-sulfo Galactosylceramide (d18:1/16:0)已被用作量化大鼠小脑和多发性硬化症患者分离的白质中的硫化物的参照物。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01632 |
MRC1 Protein, Human, Recombinant (His)
Human mannose receptor,C-type lectin domain family 13 member... |
Human | E. coli |
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.; (Microbial infection) Interacts with Hepatitis B virus envelope protein. MRC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.9... | |||
TMPH-02813 |
Nidogen-1 Protein, Mouse, Recombinant (E. coli, His)
Nid1,Nidogen-1,Entactin |
Mouse | E. coli |
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. Nidogen-1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is P10493. | |||
TMPH-02812 |
Nidogen-1 Protein, Mouse, Recombinant (His)
Nid1,Nidogen-1,Entactin |
Mouse | P. pastoris (Yeast) |
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. | |||
TMPH-03012 |
HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Adhesin,Heparin-binding hemagglutinin,hbhA |
Mycobacterium tuberculosis | E. coli |
Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells. HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.8 kDa and the accession number is P9WIP8. | |||
TMPH-02611 |
Langerin/CD207 Protein, Mouse, Recombinant (His)
C-type lectin domain family 4 member K,Langerin,Cd207 |
Mouse | E. coli |
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. | |||
TMPH-00794 |
Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)
napA,DNA protection during starvation protein,Bacterioferrit... |
Helicobacter pylori | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role... | |||
TMPY-01660 |
SULT1E1 Protein, Human, Recombinant (His)
ST1E1,EST,sulfotransferase family 1E member 1,EST-1,STE,MGC3... |
Human | E. coli |
Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradio... | |||
TMPJ-01369 |
DPT Protein, Mouse, Recombinant (hFc)
EQ-1,Early quiescence protein 1,TRAMP,Tyrosine-rich acidic m... |
Mouse | HEK293 Cells |
Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growths such as leiomyoma and scar tissue, inhibits cell proliferation, accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation, Dermatopontin deficient mice exhibit altered collagen matrix deposition and organization. Dermatopontin s... | |||
TMPJ-00445 |
IBSP Protein, Mouse, Recombinant (His)
BNSP,IBSP,Integrin binding sialoprotein,Cell binding sialopr... |
Mouse | HEK293 Cells |
Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesized as a 324 amino acid (aa) precursor that contains a 16 aa signal sequence and a 308 aa mature region. The mature segment is divided into a basic N‑terminus (aa 17 ‑ 62), a central region (aa 63 ‑ 233), and an acidic C‑terminus (aa 234 ‑ 317). IBSP is highly glycosylated, sulfate... | |||
TMPY-01707 |
CHST15 Protein, Human, Recombinant (His)
BRAG,carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulf... |
Human | HEK293 Cells |
Carbohydrate sulfotransferase 15, also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST, B-cell RAG-associated gene protein, CHST15 and BRAG, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family. CHST15 / BRAG is expressed in B-cell-enriched tissues but not in fetal or adult thymus. It is expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. It is not expressed in T-cells. In pro-B, pre... | |||
TMPJ-01361 |
Siglec-8 Protein, Human, Recombinant (mFc)
CD329 antigen,Siglec-8,SAF2SAF-2,CDw329,Siglec8,SAF-2,SAF2 |
Human | HEK293 Cells |
Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c... | |||
TMPY-04070 |
Citrate Synthase Protein, Human, Recombinant (His)
citrate synthase |
Human | Baculovirus Insect Cells |
Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers. Overwhelming evidence over recent years indicates that sulphation motif sequences within the CS chain structure are a source of significant biological information to cells and their surrounding environment. CS sulphation motifs have been shown to interact with a wide variety of bioactive molecules, e.g. cytokines, growth factors, ... | |||
TMPY-00950 |
WISP1/CCN4 Protein, Human, Recombinant (His)
WISP1c,WISP1i,CCN4,WNT1 inducible signaling pathway protein ... |
Human | HEK293 Cells |
CCN4/Wnt-induced secreted protein 1 (WISP1) is a secreted, cysteine-rich, heparin-binding glycoprotein, belonging to the CCN (CTGF/CYR61/NOV) family of growth factors, and is involved in diverse biological functions such as cell growth, adhesion, migration, angiogenesis, tissue repair, and regulation of extracellular matrix. Members of the CCN family demonstrate high structural homology sharing four conserved cysteine-rich modular domains: an IGFBP (insulin-like growth factor-binding) domain, a ... | |||
TMPJ-00220 |
B3GAT1 Protein, Human, Recombinant (His)
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)... |
Human | HEK293 Cells |
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. It adds a glucuronic residue to the terminal lactosamine residue (Gal beta 14GlcNAc) of a glycoprotein or glycolipid, which can be further sulfated to become the HNK1 epitope, a unique trisaccharide structure, HSO3-3GlcA beta 1-3Gal beta 1-4GlcNAc. The enzyme activity was found to be enhanced in the presence of sphingomyelin an... |