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Search Results for " monoamine "

Targets Recommended: Monoamine Transporter Monoamine Oxidase Others

195

抑制剂 & 化合物

40

天然产物

2

化合物库

4

重组蛋白

9

同位素标记化合物

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Cat. No.	Product Name
L2800	5-羟色胺分子库		268 compounds
	268 种生物活性小分子化合物，用于高通量、高内涵筛选；
L9830	抗帕金森病化合物库		857 compounds
	857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

5-羟色胺分子库

Cat.No: L2800

Compounds: 268

抗帕金森病化合物库

Cat.No: L9830

Compounds: 857

Cat. No.	Product Name	Target	Signaling Pathways
T75422	Monoamine oxidase	Others	Others
	Monoamine oxidase 是一种由不同多肽组成的酶。Monoamine oxidase 通过产生过氧化氢催化大脑和外周组织中多种生物胺氧化脱氨。Monoamine oxidase 在维持突触神经传递、情绪行为和其他大脑功能的调节中发挥重要作用。
T61463	Monoamine oxidase/Aromatase-IN-1	Others	Others
	Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potential for research in neurological disorders and breast cancer [1].
T60656	Monoamine Oxidase B inhibitor 1	Others	Others
	Monoamine Oxidase B inhibitor 1 是一种可逆、口服有效和选择性的单胺氧化酶 B 抑制剂 (IC50 = 0.02 nM)，可以穿过血脑屏障 (BBB)。Monoamine Oxidase B inhibitor 1 显示出抗氧化和抗神经炎症活性，可用于研究帕金森病。
T60806	Monoamine Oxidase B inhibitor 2	Others	Others
	Monoamine Oxidase B inhibitor 2 是有可逆并且口服有效的和选择性的单胺氧化酶 B (MAO-B) 抑制剂(IC50 = 1.33 nM) ，可以透过血脑屏障 (BBB)。Monoamine Oxidase B inhibitor 2 显示出抗氧化和抗神经炎症活性，可用于研究帕金森病。
T8849	PF-9601N	MAO	Metabolism; Neuroscience
	PF-9601N 是一种单胺氧化酶 B (MAO-B) 抑制剂，在多种体内外模型中表现出抗帕金森病 (PD) 的神经保护作用。它可用于研究兴奋性毒性介导的神经退行性疾病。
T0235	Modaline sulfate	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Modaline sulfate 是一种 MAO 抑制剂，用于研究抑郁症。
T4559	Isocarboxazid	Monoamine Oxidase	Neuroscience
	Isocarboxazid 是不可逆的、非选择性的单胺氧化酶 monoamine oxidase 抑制剂，其在大鼠大脑中测得的 IC50值为4.8 μM。
T22605	Bifemelane hydrochloride	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Bifemelane hydrochloride 是一种选择性的，有效的，和竞争性的单胺氧化酶A (MAO-A)抑制剂，Ki=4.20 μM，它也非竞争性地抑制MAO-B，Ki=46.0 μM。它具有显著的抗抑郁作用，可用于研究与脑血管疾病有关的认知和情绪障碍。
T7147	Valbenazine NBI-98854	Monoamine Transporter	Membrane transporter/Ion channel
	Valbenazine (NBI-98854) 是一种高度选择性的囊泡单胺转运蛋白 2 (VMAT2) 抑制剂，Ki 为 110-190 nM，用于治疗迟发性运动障碍。
T7626	Budipine	Others	Others
	Budipine 是抗帕金森病剂的一种。
T16803	RS 8359	MAO	Metabolism; Neuroscience
	RS 8359 是单胺氧化酶 A (MAO-A) 的可逆抑制剂，对 A:B 酶类型的特异性比约为 2200。 RS 8359 具有抗抑郁活性。
T0084	Moclobemide 吗氯贝胺,Ro111163	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Moclobemide (Ro111163) 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂，能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
T12585	PXS-5153A	Others; Monoamine Oxidase	Neuroscience; Others
	PXS-5153A 是一种有效、特异性和速效的Lysyl Oxidase-like 2/3 (LOXL2/3) 抑制剂，其酶活性在 15 分钟内几乎完全阻断。 PXS-5153A 可以减少交联并改善纤维化。
T12584	PXS-5120A	Others; Monoamine Oxidase	Neuroscience; Others
	PXS-5120A 是一种不可逆的 Lysyl Oxidase-like 2/3 (LOXL2/3) 的氟代烯丙胺抑制剂，具有抗纤维化活性。
T1993	J-147 J147	Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase	Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
	J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂，可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体，EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
T6073	OG-L002	Histone Demethylase; Monoamine Oxidase; HSV	Chromatin/Epigenetic; Microbiology/Virology; Neuroscience
	OG-L002 是一种高度选择性的 LSD1有效抑制剂，IC50为 0.02 μM。它抑制HSV IE 基因的表达，还是单胺氧化酶抑制剂，对 MAO-A 和 MAO-B 的IC50分别为 1.38 μM 和 0.72 μM。
T3596	TB5	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	TB5 是一种选择性可逆 hMAO-B 有效抑制剂，Ki=0.11±0.01 μM。
T7185	(2-Chloropyridin-4-yl)MethanaMine Hydrochloride	Monoamine Oxidase	Neuroscience
	(2-Chloropyridin-4-yl)methanamine hydrochloride 是一种选择性的LOXL2抑制剂，IC50=126 nM。
T5323	Toloxatone 托洛沙酮,MD 69276	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Toloxatone (MD 69276) 是可逆的单胺氧化酶 A (MAOA) 抑制剂，是一种抗抑郁剂。
T0821	Iproniazid Phosphate 磷酸异丙烟肼,Isoproniazid phosphate	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Iproniazid Phosphate 是一种非选择性的，不可逆的单胺氧化酶抑制剂，具有抗抑郁作用。
T1455	Nialamide Nialamid,烟肼酰胺,Niamidal	MAO; Transferase; Monoamine Oxidase	Metabolism; Neuroscience
	Nialamide (Nialamid) 是非选择性的，不可逆的单胺氧化酶抑制剂，是一种抗抑郁药。
T8907	Minaprine dihydrochloride 米那卜林二盐酸盐	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Minaprine dihydrochloride 是一种可逆的单胺氧化酶 MAO-A 抑制剂，对乙酰胆碱酯酶有微弱抑制，是一种抗抑郁类化合物。
T12441	Phenelzine sulfate 硫酸苯乙肼,苯肼,硫酸盐	Monoamine Oxidase	Neuroscience
	Phenelzine sulfate 是一种非选择性的、不可逆的单胺氧化酶抑制剂 (MAOI)，可用作抗抑郁药和抗焦虑药。
T1578	Pargyline hydrochloride 优降宁盐酸盐,Pargylamine hydrochloride	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Pargyline hydrochloride (Pargylamine hydrochloride) 是不可逆的单胺氧化酶抑制剂，可作用于 MAO-A (Ki=13 μM) 和 MAO-B (Ki=0.5 μM) ，具有降压和抗癌作用。
T39986	LOX-IN-3 dihydrochloride	Lipoxygenase	Metabolism
	LOX-IN-3 dihydrochloride 是口服有效的赖氨酰氧化酶抑制剂，在纤维化，癌症和/或血管生成方面有研究价值。
T0719	Tetrabenazine Xenazine,丁苯那嗪,Ro 1-9569	Others; Dopamine Receptor; Monoamine Transporter	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience; Others
	Tetrabenazine (Ro 1-9569) 是 VMAT 抑制剂，用作抗精神病药和治疗各种运动障碍。
T5053	Eprobemide LIS 630,依普贝胺	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Eprobemide (LIS 630) 是一种非竞争性的、可逆的单胺氧化酶 A 抑制剂。
T18918	Azure B Azure B chloride,天青 B	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Azure B (Azure B chloride) 是一种 Methylene blue 的主要代谢物，是一种阳离子染料，用于 Azure 曙红染色剂以进行血液涂片染色。它是高选择性和可逆的抑制单胺氧化酶(MAO)-A 的抑制剂，对重组人的 MAO-A 和 MAO-B 的IC50分别为 11 和 968 nM。它具有显著的抗抑郁作用。
T0300	Pargyline Pargylamine,Paragyline,优降宁	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Pargyline (Pargylamine) 是不可逆的单胺氧化酶抑制剂，对MAO-A 和MAO-B 的Ki 分别为 13 μM 和 0.5 μM，具有降压和抗癌作用。
T23070	Nisoxetine hydrochloride	Sodium Channel; Monoamine Transporter; Norepinephrine	Membrane transporter/Ion channel; Neuroscience
	Nisoxetine hydrochloride 是一种去甲肾上腺素转运蛋白 (NET) 抑制剂，Kd 值为 0.76 nM。它是抗抑郁药和局部麻药，可以阻断电压门控性钠通道。
T1119	Rasagiline 雷沙吉兰,AGN1135,TVP1012	BCL; MAO; Monoamine Oxidase	Apoptosis; Metabolism; Neuroscience
	Rasagiline (AGN1135) 是不可逆的、高效的、选择性的线粒体单胺氧化酶 (MAO) 抑制剂，抑制大鼠脑 MAO B 和 MAO A 的 IC50分别为 4.43 nM 和 412 nM。
T7942	Tranylcypromine hemisulfate Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐	Histone Demethylase; MAO; Monoamine Oxidase	Chromatin/Epigenetic; Metabolism; Neuroscience
	Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂，可用于研究抑郁症和子宫内膜异位症。
T22714	Decynium 22	Others	Others
	Decynium 22 是有机阳离子转运蛋白和单胺转运蛋白的抑制剂，具有抗抑郁作用。
T7048	1,4-Naphthoquinone α-Naphthoquinone,Naphthalene-1,4-Dione,P-Naphthoquinone,1,4-萘醌,para-naphthoquinone	Others; MAO; Topoisomerase	DNA Damage/DNA Repair; Metabolism; Neuroscience; Others
	1,4-Naphthoquinone (P-Naphthoquinone) 被用作单胺氧化酶和 DNA 拓扑异构酶活性的潜在抑制剂，还用于抑制乙酰转移酶活性。
T1632	Amitraz BTS-27419,NSC 324552,双甲脒	Adrenergic Receptor; Parasite; Monoamine Oxidase	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Amitraz (NSC 324552) 是一种非系统性杀螨剂和杀虫剂,，可治疗犬蠕形螨。它具有α-肾上腺素能激动剂活性, 与中枢神经系统的章鱼胺受体相互作用, 抑制单胺氧化酶和前列腺素合成。
T26795	PXS-4728A BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl	Monoamine Oxidase	Neuroscience
	BI-1467335 HCl(BI 1467335) 是口服具有活性的、选择性的氨基脲敏感性胺氧化酶(SSAO) 抑制剂。PXS-4728A (BI 1467335) 能够改善小鼠的慢性阻塞性肺疾病。
T8589	(±)-Amiflamine 4-(dimethylamino)-alpha,4-(2-氨基丙基)-N,N,3-三甲基苯胺,Amiflamine,2-dimethylphenethylamine	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	(±)-Amiflamine (2-dimethylphenethylamine) 是一种单胺氧化酶(MAO-A)，pIC50=5.57。
T2315	GSK-LSD1 dihydrochloride GSK-LSD1 (hydrochloride),GSK-LSD1 2HCl	Histone Demethylase	Chromatin/Epigenetic
	GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) 是一种特异性不可逆的 LSD1 抑制剂(IC50: 16 nM)。GSK-LSD1 dihydrochloride 对 LSD1 的选择性是其他密切相关的 FAD 利用酶（即 MAO-A、LSD2、MAO-B）的 1000 倍以上。
T1117	Clorgyline hydrochloride 盐酸氯吉林,Clorgiline hydrochloride,N-[3-(2,4-二氯苯氧基)丙基]-N-甲基-2-丙炔胺盐酸盐	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Clorgyline hydrochloride (Clorgiline hydrochloride) 是一种选择性、不可逆的单胺氧化酶A 抑制剂，结构上与Pargyline 相关。
T6962	Rasagiline Mesylate TVP1012,甲磺酸雷沙吉兰,AGN1135,Azilect	Apoptosis; MAO; Autophagy; Monoamine Oxidase	Apoptosis; Autophagy; Metabolism; Neuroscience
	Rasagiline Mesylate (AGN1135) 是一种高效的，不可逆的选择性线粒体单胺氧化酶 (MAO) 抑制剂，抑制大鼠脑 MAO B 和 MAO A 的IC50分别为 4.43 nM 和 412 nM。
T3534	Tetrabenazine Racemate Nitoman,丁苯那嗪外消旋体,丁苯那嗪,Ro 1-9569 Racemate,Rubigen,TETRABENAZINE	Monoamine Transporter	Membrane transporter/Ion channel
	Tetrabenazine Racemate (Rubigen) 是一种选择性和可逆的囊泡单胺转运蛋白 2(VMAT-2) 抑制剂。它阻断神经递质吸收到肾上腺素能储存囊泡中，并已被用作囊泡运输系统的高亲和力标记。
T5678	Lazabemide hydrochloride N-(2-Aminoethyl)-5-chlor-2-pyridincarbox,拉扎贝胺盐酸盐	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) 是一种单胺氧化酶 B 的选择性的可逆抑制剂，但对 MAO-A 活性较低。它在高浓度时，具有抑制单胺摄取的作用，抑制去甲肾上腺素、血清素和多巴胺摄取。它可用于研究帕金森和阿尔茨海默病。
T4274	Melitracen hydrochloride 盐酸美利曲辛,盐酸美力他欣,Thymeol hydrochloride,Melixeran	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Melitracen hydrochloride (Thymeol hydrochloride) 是一种可口服的双相抗抑郁药和抗焦虑药。它可以通过突触前膜抑制去甲肾上腺素和5-羟色胺(5-HT)的吸收，从而诱导突触空间中单胺递质的增加。
T6352	(-)-Dizocilpine maleate C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) 是一种选择性且非竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂，Ki 为 211.7 nM。它是一种 Dizocilpine 的活性较低的 (-)-对映体，具有抗抑郁作用。
T5887	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone,3,4-二氢-7-羟基-2(1H)-喹啉酮	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 是弱MAO-A 抑制剂，IC50=183 μM，对 MAO-B 无作用。
T0006	Methylene Blue trihydrate 碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue	Guanylate cyclase; Microtubule Associated; NO Synthase; Parasite; Monoamine Oxidase	Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Methylene Blue trihydrate (Basic blue 9) 是鸟苷酸环化酶，单胺氧化酶 A 和 NO 合酶抑制剂。它是血管加压药，在医疗中通常用作染料。它具有抗伤害感受，抗疟疾，抗抑郁和抗焦虑作用，可用于高铁血红蛋白血症，神经退行性疾病和异环磷酰胺引起的脑病的研究。
T7563	NBI-98782 (+)-α-二氢丁苯那嗪,(+)-α-Dihydrotetrabenazine,(+)-α-DHTBZ,(+)-DTBZ,[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-六氢-9,10-二甲氧基-3-异丁基-2H-苯并[a]喹嗪-2-醇	Monoamine Transporter	Membrane transporter/Ion channel
	NBI-98782 ((+)-α-DHTBZ) 是一种囊泡单胺转运蛋白 (VMAT2) 抑制剂，Ki 为0.97nM。
T6888	Methylene Blue 亚甲蓝,methylthioninium chloride,CI-52015,Tetramethylthionine chloride,亚甲兰,Basic Blue 9	Guanylate cyclase; Microtubule Associated; NO Synthase; Parasite; Monoamine Oxidase	Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Methylene Blue (Tetramethylthionine chloride) 是鸟苷酸环化酶，是单胺氧化酶 A 和 NO 合酶抑制剂。它有抗伤害感受、抗疟疾、抗抑郁和抗焦虑作用，可研究高铁血红蛋白血症、神经退行性疾病和异环磷酰胺引起的脑病。它是血管加压剂，用作色素内窥镜检查中的染料。
T5470	LAZABEMIDE 拉扎贝胺,Ro 19-6327	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Lazabemide (Ro 19-6327) 是一种单胺氧化酶 B 的选择性的可逆抑制剂，但对 MAO-A 活性较低。它高浓度时具有抑制单胺摄取的作用，能够抑制去甲肾上腺素、血清素和多巴胺摄取，其IC50值分别为 86 μM、123 μM 和 >500 μM。它可用于研究帕金森和阿尔茨海默病。
T6651	Safinamide mesylate PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate,沙芬酰胺甲磺酸盐	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Safinamide mesylate (EMD 1195686 mesylate) 是选择性的、有效的、可逆的单胺氧化酶 B 的抑制剂，对 MAO-A 选择性较低。它能够阻断钠通道和调节谷氨酸释放。它具有神经保护作用，可用于研究帕金森病、缺血脑卒中等疾病。

化合物

Monoamine oxidase

Cat.No: T75422

Target: Others

Monoamine oxidase/Aromatase-IN-1

Cat.No: T61463

Target: Others

Monoamine Oxidase B inhibitor 1

Cat.No: T60656

Target: Others

Monoamine Oxidase B inhibitor 2

Cat.No: T60806

Target: Others

Cat.No: T8849

Target: MAO

Modaline sulfate

Cat.No: T0235

Target: MAO, Monoamine Oxidase

Cat.No: T4559

Target: Monoamine Oxidase

Bifemelane hydrochloride

Cat.No: T22605

Target: MAO, Monoamine Oxidase

Cat.No: T7147

Synonym: NBI-98854

Target: Monoamine Transporter

Cat.No: T7626

Target: Others

Cat.No: T16803

Target: MAO

Cat.No: T0084

Synonym: 吗氯贝胺,Ro111163

Target: MAO, Monoamine Oxidase

Cat.No: T12585

Target: Others, Monoamine Oxidase

Cat.No: T12584

Target: Others, Monoamine Oxidase

Cat.No: T1993

Synonym: J147

Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase

Cat.No: T6073

Target: Histone Demethylase, Monoamine Oxidase, HSV

Cat.No: T3596

Target: MAO, Monoamine Oxidase

(2-Chloropyridin-4-yl)MethanaMine Hydrochloride

Cat.No: T7185

Target: Monoamine Oxidase

Cat.No: T5323

Synonym: 托洛沙酮,MD 69276

Target: MAO, Monoamine Oxidase

Iproniazid Phosphate

Cat.No: T0821

Synonym: 磷酸异丙烟肼,Isoproniazid phosphate

Target: MAO, Monoamine Oxidase

Cat.No: T1455

Synonym: Nialamid,烟肼酰胺,Niamidal

Target: MAO, Transferase, Monoamine Oxidase

Minaprine dihydrochloride

Cat.No: T8907

Synonym: 米那卜林二盐酸盐

Target: MAO, Monoamine Oxidase

Phenelzine sulfate

Cat.No: T12441

Synonym: 硫酸苯乙肼,苯肼,硫酸盐

Target: Monoamine Oxidase

Pargyline hydrochloride

Cat.No: T1578

Synonym: 优降宁盐酸盐,Pargylamine hydrochloride

Target: MAO, Monoamine Oxidase

LOX-IN-3 dihydrochloride

Cat.No: T39986

Target: Lipoxygenase

Cat.No: T0719

Synonym: Xenazine,丁苯那嗪,Ro 1-9569

Target: Others, Dopamine Receptor, Monoamine Transporter

Cat.No: T5053

Synonym: LIS 630,依普贝胺

Target: MAO, Monoamine Oxidase

Cat.No: T18918

Synonym: Azure B chloride,天青 B

Target: MAO, Monoamine Oxidase

Cat.No: T0300

Synonym: Pargylamine,Paragyline,优降宁

Target: MAO, Monoamine Oxidase

Nisoxetine hydrochloride

Cat.No: T23070

Target: Sodium Channel, Monoamine Transporter, Norepinephrine

Cat.No: T1119

Synonym: 雷沙吉兰,AGN1135,TVP1012

Target: BCL, MAO, Monoamine Oxidase

Tranylcypromine hemisulfate

Cat.No: T7942

Synonym: Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐

Target: Histone Demethylase, MAO, Monoamine Oxidase

Cat.No: T22714

Target: Others

1,4-Naphthoquinone

Cat.No: T7048

Synonym: α-Naphthoquinone,Naphthalene-1,4-Dione,P-Naphthoquinone,1,4-萘醌,para-naphthoquinone

Target: Others, MAO, Topoisomerase

Cat.No: T1632

Synonym: BTS-27419,NSC 324552,双甲脒

Target: Adrenergic Receptor, Parasite, Monoamine Oxidase

Cat.No: T26795

Synonym: BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl

Target: Monoamine Oxidase

(±)-Amiflamine

Cat.No: T8589

Synonym: 4-(dimethylamino)-alpha,4-(2-氨基丙基)-N,N,3-三甲基苯胺,Amiflamine,2-dimethylphenethylamine

Target: MAO, Monoamine Oxidase

GSK-LSD1 dihydrochloride

Cat.No: T2315

Synonym: GSK-LSD1 (hydrochloride),GSK-LSD1 2HCl

Target: Histone Demethylase

Clorgyline hydrochloride

Cat.No: T1117

Synonym: 盐酸氯吉林,Clorgiline hydrochloride,N-[3-(2,4-二氯苯氧基)丙基]-N-甲基-2-丙炔胺盐酸盐

Target: MAO, Monoamine Oxidase

Rasagiline Mesylate

Cat.No: T6962

Synonym: TVP1012,甲磺酸雷沙吉兰,AGN1135,Azilect

Target: Apoptosis, MAO, Autophagy, Monoamine Oxidase

Tetrabenazine Racemate

Cat.No: T3534

Synonym: Nitoman,丁苯那嗪外消旋体,丁苯那嗪,Ro 1-9569 Racemate,Rubigen,TETRABENAZINE

Target: Monoamine Transporter

Lazabemide hydrochloride

Cat.No: T5678

Synonym: N-(2-Aminoethyl)-5-chlor-2-pyridincarbox,拉扎贝胺盐酸盐

Target: MAO, Monoamine Oxidase

Melitracen hydrochloride

Cat.No: T4274

Synonym: 盐酸美利曲辛,盐酸美力他欣,Thymeol hydrochloride,Melixeran

Target: Dopamine Receptor, 5-HT Receptor

(-)-Dizocilpine maleate

Cat.No: T6352

Synonym: C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate

Target: NMDAR, iGluR

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Cat.No: T5887

Synonym: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone,3,4-二氢-7-羟基-2(1H)-喹啉酮

Target: MAO, Monoamine Oxidase

Methylene Blue trihydrate

Cat.No: T0006

Synonym: 碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Cat.No: T7563

Synonym: (+)-α-二氢丁苯那嗪,(+)-α-Dihydrotetrabenazine,(+)-α-DHTBZ,(+)-DTBZ,[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-六氢-9,10-二甲氧基-3-异丁基-2H-苯并[a]喹嗪-2-醇

Target: Monoamine Transporter

Cat.No: T6888

Synonym: 亚甲蓝,methylthioninium chloride,CI-52015,Tetramethylthionine chloride,亚甲兰,Basic Blue 9

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Cat.No: T5470

Synonym: 拉扎贝胺,Ro 19-6327

Target: MAO, Monoamine Oxidase

Safinamide mesylate

Cat.No: T6651

Synonym: PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate,沙芬酰胺甲磺酸盐

Target: MAO, Monoamine Oxidase

Cat. No.	Product Name	Target	Signaling Pathways
TN1120	Osthenol	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Osthenol 是一种前酰化香豆素，从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用，IC50=0.74 µM，对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T3152	Harmol 哈尔酚(骆驼蓬醇),Methylpyridoindolol	Others; Monoamine Oxidase	Neuroscience; Others
	Harmol 一种 β-carboline 生物碱，是单胺氧化酶抑制剂，可用作分析参考标准品。
T4024	Norharmane 2-Azacarbazole,2,9-Diazafluorene,β-Carboline,去甲哈尔满	DNA; Endogenous Metabolite; Monoamine Oxidase	DNA Damage/DNA Repair; Metabolism; Neuroscience
	Norharmane (β-Carboline) 是一种有效的选择性单胺氧化酶 A (MAO-A) 抑制剂，Ki=3.34 μM。
T2900	Paeonol 丹皮酚,Peonol	MAO; Autophagy; Monoamine Oxidase	Autophagy; Metabolism; Neuroscience
	Paeonol (Peonol) 是一种从牡丹中提取的活性物质，可抑制 MAO-A 和 MAO-B，IC50 分别为 54.6 μM 和 42.5 μM。
TN2004	Obtusin 1,7-二羟基-2,3,8-三甲氧基-6-甲基蒽-9,10-二酮,决明素	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Obtusin 是来自决明子种子，是一种高度选择性和竞争性的人单胺氧化酶-A 抑制剂，IC50=11.12 μM，Ki=6.15 μM。它在神经退行性疾病，尤其是焦虑和抑郁中起预防作用。
T0791	Reserpine 利血平,Serpalan,Serpasil,Serpivite	Others; Potassium Channel; MRP; Monoamine Transporter; Autophagy	Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others
	Reserpine (Serpalan) 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中，导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。
T6862	Isatin Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione	Apoptosis; MAO; Monoamine Oxidase	Apoptosis; Metabolism; Neuroscience
	Isatin (2,3-Indolinedione) 是一种单胺氧化酶抑制剂，IC50为3 μM。它也可作为心钠肽刺激和一氧化氮刺激的鸟苷酸环化酶活性的拮抗剂，显示对血清素系统有影响。
T3158	Harmane Loturine,Harman,Aribine,哈尔满碱	Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor	GPCR/G Protein; Neuroscience
	Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱，是有效的神经毒素，可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂，具有致突变作用，对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。
T3885	ROSIRIDIN 6'-O-Deacetylrosiridoside C,络塞定,(-)-Rosiridin	Others; Monoamine Oxidase	Neuroscience; Others
	Rosiridin (6'-O-Deacetylrosiridoside C) 能够抑制 MAO A 和 MAO B，有潜在的抑郁症和老年性痴呆作用。它在 10 μM 时对 MAO B 的抑制率为 83.8% (pIC50=5.38)。
T5S0734	Desmethoxyyangonin Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain	Others; Monoamine Oxidase	Neuroscience; Others
	Desmethoxyyangonin (5,6-Dehydrokavain) 是一种MAO-B 可逆性抑制剂。
T2765	Rosmarinic acid Labiatenic acid,迷迭香酸,Rosemary acid	Apoptosis; IκB/IKK; MAO; Endogenous Metabolite; Transferase; Monoamine Oxidase	Apoptosis; Metabolism; Neuroscience; NF-κB
	Rosmarinic acid (Labiatenic acid) 广泛存在植物中，具有抗氧化、抗炎和抗菌活性。它抑制 MAO-A，MAO-B 和 COMT，IC50分别为 50.1，184.6 和 26.7 μM。
T13475	β-Aminopropionitrile 3-氨基丙腈,3-Aminopropionitrile,BAPN	Others; Endogenous Metabolite	Metabolism; Others
	β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T6S0923	Hypericin Hypericine,金丝桃素,Cyclosan	Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Hypericin (Cyclosan) 是贯叶连翘的提取物，有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
TN7211	Tetrahydroharmine Leptaflorine	MAO	Metabolism; Neuroscience
	Tetrahydroharmine (Leptaflorine) 是一种天然产物，存在于植物Banisteriopsis caapi cultivar Da Vine 的茎和枝中。四氢骆驼蓬碱是一种Monoamine oxidase A 抑制剂。
Fr12415	Ethyl 4-hydroxyphenylacetate	Others	Others
	Ethyl 4-hydroxyphenylacetate 是单胺氧化酶 A 的选择性抑制剂。
TN1705	Glycyrrhisoflavone	MAO; Tyrosinase; NO Synthase; Immunology/Inflammation related	Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome
	Glycyrrhisoflavone 是一种具有抗炎作用的酪氨酸酶抑制剂。 Glycyrrhisoflavone 抑制 α-葡萄糖苷酶和单胺氧化酶。
T2209	Serotonin hydrochloride 5-HT hydrochloride,5-羟基色胺盐酸盐,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride	5-HT Receptor; Endogenous Metabolite; Transferase	GPCR/G Protein; Metabolism; Neuroscience
	Serotonin hydrochloride (Serotonin HCl) 是一种内源性 5-HT 受体激动剂、CNS 中的单胺神经递质和儿茶酚 O-甲基转移酶 (COMT) 抑制剂，Ki 值为 44 μM。
TC0022	Desoxypeganine Deoxypeganine	AChE	Neuroscience
	Desoxypeganine (Deoxypeganine) 是胆碱酯酶的抑制剂。它优先作用于丁酰胆碱酯酶，作为单胺氧化酶 A 而不是单胺氧化酶 B 的选择性抑制剂。它在酒精滥用的药理学治疗中的潜在用途，以减少酒精滥用者的渴望和抑郁，并且也可能有用作为戒烟辅助。
T13354	Xanthoangelol	Apoptosis; Monoamine Transporter; Antibacterial; AMPK	Apoptosis; Chromatin/Epigenetic; Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Xanthoangelol 可从 Angelica keiskei 中提取得到，对肥胖引起的炎症反应有抑制作用。Xanthoangelol 具有抗菌活性，对单胺氧化酶有抑制作用，还诱导神经母细胞瘤和白血病细胞凋亡。
T3933	Jatrorrhizine Yatrorizine,neprotin,药根碱	MAO; 5-HT Receptor; Antibacterial; AChE	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱，具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T0647	Tryptamine	Dehydrogenase; 5-HT Receptor; Endogenous Metabolite; TRP/TRPV Channel	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Tryptamine 是一种在动物、植物和真菌中发现的单胺生物碱。它含有吲哚环结构，结构类似于色氨酸。在哺乳动物的大脑中发现了微量这种物质，并被认为是一种神经递质或神经调节剂。
TN1470	Cassiaside B2 决明子苷B2	Phosphatase; MAO; 5-HT Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Cassiaside B2 是蛋白酪氨酸磷酸酶1B (PTP1B) 和人单胺氧化酶A (hMAO-A) 的抑制剂。Cassiaside B2是 5-HT2C 受体的激动剂，具有抗过敏活性。Cassiaside B2 是萘吡喃酮参比提取物（NRE）的有效成分之一。
T0469	Octopamine hydrochloride 章鱼胺盐酸盐,(±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl,章胺盐酸盐	Dopamine Receptor; Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) 是一种与去甲肾上腺素结构相关的生物单胺类物质，在无脊椎动物中起着神经调节剂、神经激素和神经递质的作用。它对转染人 alpha2-肾上腺素受体(ARs)的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。它提高糖原分解、糖酵解、糖异生、摄氧量和门脉灌注压。
T3095	Tyramine 4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine	MAO; Endogenous Metabolite	Metabolism; Neuroscience
	Tyramine (Uteramine) 是天然存在于体内或某些食物中的氨基酸。Tyramine 有助于调节血压。
T3822	Bellidifolin Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Bellidifolin (Bellidifoline) 是从獐牙菜的茎中提取的一种呫吨酮，它能作为病毒蛋白 R 的抑制剂，具有保肝、降血糖、抗炎、抗氧化、抗肿瘤作用。
T1311	4-aminobenzoic acid PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸	Endogenous Metabolite	Metabolism
	4-aminobenzoic acid 是一种具有紫外线吸收和抗纤维化特性的有机酸。当暴露在光线下时，4-aminobenzoic acid 吸收紫外线并通过光化学反应释放多余的能量，这可能会对DNA造成损害。4-aminobenzoic acid 还可以增加组织水平的摄氧量，并可能增强单胺氧化酶（MAO）活性以促进血清素的降解，过量可能导致纤维化变化。
T4848	Mandelic acid acidomandelico,DL-Mandelic acid,扁桃酸	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸，有抗菌活性，广泛用作医药和精细化学品的中间体，已用于研究尿路感染和阴道滴虫病，还具有较高的精子固定活性和较低的阴道刺激性。
TN3918	Echitovenidine	MAO	Metabolism; Neuroscience
	Echitovenidine shows monoamine oxidase inhibitor activity.
T36950	Rubrofusarin triglucoside	Others	Others
	Rubrofusarin triglucoside is a glycoside compound isolated from Cassia obtusifolia Linn seeds. Rubrofusarin triglucoside inhibits human monoamine oxidase A (hMAO-A) with an IC50 of 85.5 μM[1]. [1]. Pradeep Paudel, et al. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study. ACS Omega. 2019 Jul 3;4(7):11621-11630.
TN4137	Glicoricone	MAO	Metabolism; Neuroscience
	Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
TN3693	Confluentic acid	Others	Others
	Confluentic acid shows selective inhibition of Monoamine oxidase B with IC50 value of 0.22 microM.
T40244	Methyl citrate	Others	Others
	Methyl citrate, obtained from Opuntia ficus-indica var. saboten Makino fruits, serves as a potent Monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 0.23 mM.
TN2790	2'-O-Methylperlatolic acid	MAO	Metabolism; Neuroscience
	2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
T32208	Isogentisin BRN 0258402,BRN-0258402,BRN0258402	MAO	Metabolism; Neuroscience
	Isogentisin (BRN 0258402) 是一种从龙胆科植物中分离出来的化合物，是一种用于预防吸烟引起的内皮损伤的新型化合物。Isogentisin 对单胺氧化酶具有抑制作用。
TN3116	5-Hydroxy-1-methoxyxanthone	MAO; Antifection	Metabolism; Microbiology/Virology; Neuroscience
	5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B.
TN3726	Cudraflavone B	IκB/IKK; MAO; ROS; Akt; COX; PI3K; Nrf2; Autophagy	Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may be a lead for the development of a potential candidate for human oral squamous cell carcinoma cells.
T40576	(S)-Salsolidine	Others	Others
	(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boasting a K i value of 26 μM compared to the S form.
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to inhibit growth and metastasis of brea
T79979	Methyl piperate	Monoamine Oxidase	Neuroscience
	Methylpiperate，一种胡椒碱类生物碱，展现出显著的MAO抑制活性(IC50 3.6 μM)。该化合物对MAO-B的选择性抑制作用(IC50 1.6 μM)优于对MAO-A(IC50 27.1 μM)，因此可用于治疗精神障碍。
T37911	cis-Resveratrol 顺式白藜芦醇,(Z)-Resveratrol	Others	Others
	Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the &#181M range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase ...

天然产物

Cat.No: TN1120

Target: MAO, Monoamine Oxidase

Cat.No: T3152

Synonym: 哈尔酚(骆驼蓬醇),Methylpyridoindolol

Target: Others, Monoamine Oxidase

Cat.No: T4024

Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline,去甲哈尔满

Target: DNA, Endogenous Metabolite, Monoamine Oxidase

Cat.No: T2900

Synonym: 丹皮酚,Peonol

Target: MAO, Autophagy, Monoamine Oxidase

Cat.No: TN2004

Synonym: 1,7-二羟基-2,3,8-三甲氧基-6-甲基蒽-9,10-二酮,决明素

Target: MAO, Monoamine Oxidase

Cat.No: T0791

Synonym: 利血平,Serpalan,Serpasil,Serpivite

Target: Others, Potassium Channel, MRP, Monoamine Transporter, Autophagy

Cat.No: T6862

Synonym: Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione

Target: Apoptosis, MAO, Monoamine Oxidase

Cat.No: T3158

Synonym: Loturine,Harman,Aribine,哈尔满碱

Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor

Cat.No: T3885

Synonym: 6'-O-Deacetylrosiridoside C,络塞定,(-)-Rosiridin

Target: Others, Monoamine Oxidase

Desmethoxyyangonin

Cat.No: T5S0734

Synonym: Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

Rosmarinic acid

Cat.No: T2765

Synonym: Labiatenic acid,迷迭香酸,Rosemary acid

Target: Apoptosis, IκB/IKK, MAO, Endogenous Metabolite, Transferase, Monoamine Oxidase

β-Aminopropionitrile

Cat.No: T13475

Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN

Target: Others, Endogenous Metabolite

Cat.No: T6S0923

Synonym: Hypericine,金丝桃素,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Tetrahydroharmine

Cat.No: TN7211

Synonym: Leptaflorine

Target: MAO

Ethyl 4-hydroxyphenylacetate

Cat.No: Fr12415

Target: Others

Glycyrrhisoflavone

Cat.No: TN1705

Target: MAO, Tyrosinase, NO Synthase, Immunology/Inflammation related

Serotonin hydrochloride

Cat.No: T2209

Synonym: 5-HT hydrochloride,5-羟基色胺盐酸盐,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride

Target: 5-HT Receptor, Endogenous Metabolite, Transferase

Cat.No: TC0022

Synonym: Deoxypeganine

Target: AChE

Cat.No: T13354

Target: Apoptosis, Monoamine Transporter, Antibacterial, AMPK

Cat.No: T3933

Synonym: Yatrorizine,neprotin,药根碱

Target: MAO, 5-HT Receptor, Antibacterial, AChE

Cat.No: T0647

Target: Dehydrogenase, 5-HT Receptor, Endogenous Metabolite, TRP/TRPV Channel

Cat.No: TN1470

Synonym: 决明子苷B2

Target: Phosphatase, MAO, 5-HT Receptor

Octopamine hydrochloride

Cat.No: T0469

Synonym: 章鱼胺盐酸盐,(±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl,章胺盐酸盐

Target: Dopamine Receptor, Endogenous Metabolite, Adrenergic Receptor

Cat.No: T3095

Synonym: 4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine

Target: MAO, Endogenous Metabolite

Cat.No: T3822

Synonym: Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮

Target: Others, HIV Protease

4-aminobenzoic acid

Cat.No: T1311

Synonym: PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸

Target: Endogenous Metabolite

Cat.No: T4848

Synonym: acidomandelico,DL-Mandelic acid,扁桃酸

Target: Others, Endogenous Metabolite, Antibacterial

Cat.No: TN3918

Target: MAO

Rubrofusarin triglucoside

Cat.No: T36950

Target: Others

Cat.No: TN4137

Target: MAO

Confluentic acid

Cat.No: TN3693

Target: Others

Cat.No: T40244

Target: Others

2'-O-Methylperlatolic acid

Cat.No: TN2790

Target: MAO

Cat.No: T32208

Synonym: BRN 0258402,BRN-0258402,BRN0258402

Target: MAO

5-Hydroxy-1-methoxyxanthone

Cat.No: TN3116

Target: MAO, Antifection

Cat.No: TN3726

Target: IκB/IKK, MAO, ROS, Akt, COX, PI3K, Nrf2, Autophagy

(S)-Salsolidine

Cat.No: T40576

Target: Others

Cudratricusxanthone A

Cat.No: TN5901

Methyl piperate

Cat.No: T79979

Target: Monoamine Oxidase

cis-Resveratrol

Cat.No: T37911

Synonym: 顺式白藜芦醇,(Z)-Resveratrol

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02880	Renalase Protein, Mouse, Recombinant (His & SUMO) Monoamine oxidase-C,Renalase,Rnls	Mouse	E. coli
	Renalase Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.0 kDa and the accession number is A7RDN6.
TMPH-00926	MAOB Protein, Human, Recombinant (His) Amine oxidase [flavin-containing] B,Monoamine oxida...	Human	E. coli
	MAOB Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00379	AOC3 Protein, Human, Recombinant (hFc) SSAO,AOC3,Membrane primary amine oxidase,Copper amine oxidas...	Human	HEK293 Cells
	Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam...
TMPY-03056	LSD1 Protein, Human, Recombinant (His & GST) BHC110,LSD1,KDM1,AOF2,lysine (K)-specific demethylase 1A	Human	Baculovirus Insect Cells
	LSD1 belongs to the flavin monoamine oxidase family. It contains 1 SWIRM domain and is a component of an RCOR/GFI/LSD1/HDAC complex. LSD1 interacts directly with GFI1 and GFI1B. LSD1 specifically removes histone H3K4me2 to H3K4me1 or H3K4me0 through a FAD-dependent oxidative reaction. When forming a complex with an androgen receptor (and possibly other nuclear hormone receptors), LSD1 changes its substrates to H3K9me2. Thus LSD1 is considered to act as a coactivator or a corepressor. It may play...

重组蛋白

Renalase Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02880

Species: Mouse

Expression System: E. coli

MAOB Protein, Human, Recombinant (His)

Cat.No: TMPH-00926

Species: Human

Expression System: E. coli

AOC3 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00379

Species: Human

Expression System: HEK293 Cells

LSD1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03056

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
T12693	Rasagiline 13C3 mesylate racemic TVP1012 13C3 racemic,AGN1135 13C3 racemic	Others	Others
	Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.
TMID-0191	Moclobemide-d8
	Moclobemide-d8 是 Moclobemide 的氘代化合物。Moclobemide 的 CAS 号为 71320-77-9。Moclobemide 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂，能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
TMIH-0352	Moclobemide-d4
	Moclobemide-d4 是 Moclobemide 的氘代化合物。Moclobemide 的 CAS 号为 71320-77-9。Moclobemide 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂，能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
T12701	(rel)-Tranylcypromine D5 hydrochloride 2-Phenylcyclopropylamine D5 hydrochloride	Histone Demethylase	Chromatin/Epigenetic
	(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective inhibitor of monoamine oxidase (MAO) used in the treatment of depression.
T23983	Deutetrabenazine metabolite M4 SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4
	Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake
TMIJ-0100	(3R,11bR)-Tetrabenazine-d6
	(3R,11bR)-Tetrabenazine-d6 是 (3R,11bR)-Tetrabenazine 的氘代化合物。(3R,11bR)-Tetrabenazine 的 CAS 号为 1026016-83-0。(+)-Tetrabenazine是一种可逆的囊泡单胺转运蛋白2 (VMAT-2)抑制剂，对VMAT2转运的抑制作用是VMAT1的10倍。
T70174	Pirlindole-d4 HCl
	Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A over MAO-B. In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackieviru...
T36903	Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...
TMID-0056	(±)-Mandelic-2,3,4,5,6-d5 Acid
	(±)-Mandelic-2,3,4,5,6-d5 Acid 是 (±)-Mandelic Acid 的氘代化合物。(±)-Mandelic Acid 的 CAS 号为 90-64-2。DL-Mandelic acid 是一种 α-羟基羧酸，有抗菌活性，广泛用作医药和精细化学品的中间体，已用于研究尿路感染和阴道滴虫病，还具有较高的精子固定活性和较低的阴道刺激性。

同位素标记化合物

Rasagiline 13C3 mesylate racemic

Cat.No: T12693

Synonym: TVP1012 13C3 racemic,AGN1135 13C3 racemic

Target: Others

Cat.No: TMID-0191

Cat.No: TMIH-0352

(rel)-Tranylcypromine D5 hydrochloride

Cat.No: T12701

Synonym: 2-Phenylcyclopropylamine D5 hydrochloride

Target: Histone Demethylase

Deutetrabenazine metabolite M4

Cat.No: T23983

Synonym: SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4

(3R,11bR)-Tetrabenazine-d6

Cat.No: TMIJ-0100

Pirlindole-d4 HCl

Cat.No: T70174

Rasagiline-13C3 (mesylate)

Cat.No: T36903

Synonym: Rasagiline-13C3 (mesylate)

(±)-Mandelic-2,3,4,5,6-d5 Acid

Cat.No: TMID-0056

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