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MeSeI 在对单胺氧化酶MAO-A和MAO-B的作用中显示出较弱的抑制活性,其IC50为198.8 µM.该化合物还能够调控多巴胺受体D2及去甲肾上腺素受体α2、β1,且在小鼠体内展示出抗抑郁样效果.此外,MeSeI 具备良好的口服生物活性.
MeSeI 在对单胺氧化酶MAO-A和MAO-B的作用中显示出较弱的抑制活性,其IC50为198.8 µM.该化合物还能够调控多巴胺受体D2及去甲肾上腺素受体α2、β1,且在小鼠体内展示出抗抑郁样效果.此外,MeSeI 具备良好的口服生物活性.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | MeSeI exhibits weak inhibitory activity against monoamine oxidases MAO-A and MAO-B, with IC50 values of 198.8 µM. It modulates dopamine receptor D2 (dopamine receptorD2) and norepinephrine receptors α2, β1 (norepinephrine receptor α2, β1), displaying antidepressant-like effects in mice. Additionally, MeSeI is orally active. |
分子量 | 362.33 |
分子式 | C21H17NSe |
CAS No. | 2901664-87-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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