首页工具

登录

搜索结果

Search Results for " liver injury "

Targets Recommended: Leukotriene Receptor Lipoxygenase LTR

63

抑制剂 & 化合物

30

天然产物

1

化合物库

9

重组蛋白

10

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L5510	肝脏毒性化合物库		1001 compounds
	1001 个肝脏毒性化合物的特有集合，可用于高通量、高内涵筛选，是毒理学研究的良好工具；

化合物库

肝脏毒性化合物库

Cat.No: L5510

Compounds: 1001

Cat. No.	Product Name	Target	Signaling Pathways
T1677	Montelukast 孟鲁司特,Singular	Leukotriene Receptor; Lipoxygenase; LTR	GPCR/G Protein; Immunology/Inflammation; Metabolism
	Montelukast (Singular) 是可口服的半胱氨酸白三烯受体1 选择性拮抗剂，可用于研究预防哮喘和肝损伤。它还可减少心脏损伤，在肠缺血-再灌注损伤中也具有抗氧化作用。
T1677L	Montelukast sodium MK0476,孟鲁司特钠	Leukotriene Receptor; LTR	GPCR/G Protein; Immunology/Inflammation
	Montelukast sodium (MK0476) 是可口服的半胱氨酸白三烯受体1 选择性拮抗剂，可用于研究预防哮喘和肝损伤。它还可减少心脏损伤，在肠缺血-再灌注损伤中也具有抗氧化作用。
T22323	Enoxaparin sodium	Thrombin	Proteases/Proteasome
	Enoxaparin sodium 是一种低分子量肝素 (LMWH)，已获得美国 FDA 批准，可用于医疗管理的 ST 段心肌梗死 (STEMI) 或 STEMI 及随后的经皮冠状动脉介入治疗 (PCI) 患者。它与抗凝血酶结合并增强其作用，并抑制凝血因子 XIa、IXa、Xa 和 IIa（凝血酶），从而防止血栓形成。
T2171	SEW2871 SEW2871	S1P Receptor; LPL Receptor	GPCR/G Protein
	SEW 2871 是一种可口服的高选择性 S1P1激动剂，EC50为 13.8 nM。它减少血液中的淋巴细胞数量，可用于糖尿病、阿尔茨海默氏病、肝纤维化和炎症相关研究。它激活 ERK、Akt 和 Rac 信号通路，并诱导 S1P1 内在化和再循环。
T1090	Perphenazine Perphenazin,Etaperazine,Trilafon,奋乃静	CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Perphenazine (Trilafon) 是吩噻嗪衍生物和多巴胺拮抗剂，具有止吐和抗精神病特性。它能够抑制5-HT2A 受体，α1A 肾上腺素能受体，多巴胺D2、D3、D2L 受体，以及组胺H1受体，对应的Ki 值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
T14491	B022	NF-κB	NF-κB
	B022 是一种具有选择性和高效性的 NF-κB 诱导激酶（NIK）抑制剂（Ki：4.2 nM），是治疗肝脏炎症和损伤的化学探针。B022 可避免肝脏免受氧化应激和毒素引起的炎症和损伤。
T69360	RO3244794	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	RO3244794是一种具有选择性的前列环素（IP）受体拮抗剂，可用于研究肝脏损伤。
T7045	Clonidine Nexiclon,Catapres,Kapvay,可乐定	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Clonidine (Kapvay) 是 alpha2 肾上腺素能激动剂。
T11747	KD-3010	PPAR	DNA Damage/DNA Repair; Metabolism
	KD-3010(Kalypsys) 是一种具有口服活性有效性和选择性的 PPARδ 激动剂，可用于研究肝损伤。
T31795	FK-330 LS-192510,FR-260330,FK330,FK 330	NOS	Immunology/Inflammation
	FK-330（FR-260330）是一种新型口服活性诱导型一氧化氮合酶抑制剂，具有潜在的抗癌和抗肿瘤活性，可预防大鼠肝移植缺血和再灌注损伤。
T28089	mPGES-1 Inhibitor-1	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	mPGES-1 Inhibitor-1 是一种新型的微粒体前列腺素 E 合酶-1（mPGES-1）选择性抑制剂，具有抗炎镇痛活性，可用于研究急性肝损伤。
T2555	Aclidinium bromide LAS 34273,LAS-W 330,阿地溴铵	AChR	Neuroscience
	Aclidinium bromide (LAS-W 330) 是长效可吸入型的毒蕈碱拮抗剂，有用于慢性阻塞性肺病 (COPD) 的研究潜力。
T0226	Betaxolol hydrochloride 盐酸倍他洛尔,SL75212,SL 75212 HCl,Betaxolol HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Betaxolol hydrochloride (SL 75212 HCl) 是一种 β1 肾上腺素受体阻断剂，可用于研究高血压和青光眼。
T1472	Trospium chloride Spasmex,Sanctura,曲司氯铵,曲司氯胺	AChR	Neuroscience
	Trospium chloride (Spasmex) 是一种可口服的特异竞争性毒蕈碱胆碱能受体拮抗剂，可与毒蕈碱受体 M1、M2 和 M3 高亲和力结合，具有抗毒蕈碱活性。
T37859	SY-640	Endogenous Metabolite	Metabolism
	SY-640 是一种乙酰胺衍生物，显示出有效的保肝作用。SY-640 可缓解由脂多糖和痤疮丙酸杆菌诱导的小鼠肝损伤。
T17018	TCPOBOP	BCL	Apoptosis
	TCPOBOP 是一种组成型雄烷受体激动剂，可诱导强大的肝细胞增殖和肝肿大。它通过改变 Bcl-2 蛋白来减少 Fas 诱导的小鼠肝损伤。
T1655	Ambrisentan BSF-208075,BSF 208075,安倍生坦,LU 208075	Endothelin Receptor	GPCR/G Protein
	Ambrisentan (BSF 208075) 是 ET A 型受体选择性拮抗剂。
T7280	CAY10594	Phospholipase	Metabolism
	CAY10594 是磷脂酶 D2 抑制剂 (体外IC50=140 nM，细胞IC50=110 nM)。它在体外显著阻碍乳腺癌细胞的侵袭性迁移，并调节磷酸化 GSK-3β/JNK 轴改善扑热息痛诱导的急性肝损伤。
T0085L	Entecavir BMS200475,SQ34676,恩替卡韦	HBV	Microbiology/Virology
	Entecavir (SQ34676) 是一种选择性 HBV 抑制剂，在 HepG2细胞中的 EC50值为3.75 nM。
T73446	BI‑3231	Dehydrogenase	Metabolism
	BI‑3231 是一种具有选择性和高效性的羟基类固醇 17ß-脱氢酶 13 HSD17B13 抑制剂，抑制 hHSD17B13 和 mHSD17B13。BI‑3231 可用于研究酒精相关肝损伤、纤维化和肝硬化。
T1088	Repaglinide AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈	Potassium Channel; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Repaglinide (AG-EE 623ZW) 是一种能够用于2 型糖尿病的胰岛素促分泌剂。
T0805	Quinapril hydrochloride CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl	RAAS	Endocrinology/Hormones
	Quinapril hydrochloride (PD-109452-2) 是一种血管紧张素转化酶(ACE) 抑制剂的原药。
T0180	Benazepril hydrochloride 盐酸贝那普利,CGS 14824A HCl,Benazepril HCl,CGS14824A	RAAS	Endocrinology/Hormones
	Benazepril hydrochloride (CGS 14824A HCl) 是一种血管紧张素转化酶（ACE）抑制剂，能够作用于高血压。
T0929	Docusate sodium Aerosol OT,多库脂钠,Dioctyl sulfosuccinate sodium salt,Bis(2-ethylhexyl) sulfosuccinate sodium salt,Constonate	Opioid Receptor; HSV	Endocrinology/Hormones; GPCR/G Protein; Microbiology/Virology; Neuroscience
	Docusate sodium (Aerosol OT) 是一种口服的非处方泻药和大便软化剂，可用于研究便秘。
T68879	FK-330 dihydrate FR-260330 dihydrate	NO Synthase	Immunology/Inflammation
	FK-330 dihydrate（FR-260330 dihydrate）是一种新型口服活性诱导型一氧化氮合酶抑制剂，具有潜在的抗癌和抗肿瘤活性，可预防大鼠肝移植缺血和再灌注损伤。
T6875	Lesinurad RDEA594,雷西那德,来司诺雷	OAT	Membrane transporter/Ion channel
	Lesinurad (RDEA594) 是URAT1和OAT 抑制剂。Lesinurad 用作肾转运蛋白OAT1 和OAT3 的底物，Km 分别为 0.85 和 2 μM。
T0214	Pioglitazone U 72107,吡格列酮,匹格列酮	Ferroptosis; PPAR	Apoptosis; DNA Damage/DNA Repair; Metabolism
	Pioglitazone (U 72107) 是一种胰岛素增敏剂和噻唑烷二酮，适用于治疗 2 型糖尿病。它是一种选择性PPARγ激动剂，高亲和力结合到 PPARγ 配体结合域，作用于人和鼠 PPARγ的EC50分别为 0.93 和 0.99 μM。
T28248	Ono-3307 mesylate Ono-3307,Ono3307,Ono 3307	Protease	Proteases/Proteasome
	Ono-3307 mesylate 是一种蛋白酶抑制剂，对多种蛋白酶均具有抑制作用。Ono-3307 mesylate 对大鼠的肝损伤具有显着的保护作用，抑制放射性纤维蛋白在肾脏和肺部的沉积，可用于研究胰腺炎。
T16376	Odevixibat A4250	Others	Others
	Odevixibat (A4250) (A4250) 是一种有效的选择性回肠胆汁酸转运蛋白 (IBAT) 抑制剂。Odevixibat (A4250) 可减轻小鼠模型中的胆汁淤积性肝和胆管损伤。Odevixibat (A4250)可用于原发性胆汁性肝硬化的研究。
T6647	Rotigotine- Neupro,N-0923,罗替戈汀,N-0437,SPM 962	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Rotigotine (N-0923) 是多巴胺受体激动剂，是5-HT1A receptor 的部分激动剂，以及α2B-肾上腺素受体的拮抗剂，用于治疗帕金森病和不宁腿综合征。
T1189	Milnacipran hydrochloride 盐酸米那普仑,Milnacipran HCl,Savella,Dalcipran	Serotonin Transporter; Norepinephrine	Neuroscience
	Milnacipran hydrochloride (Savella) 是一种5-羟色胺-去甲肾上腺素重吸收抑制剂（SNRI），可用于纤维肌痛的研究。
T1674	Nateglinide 那格列奈,A4166,Senaglinide	Potassium Channel; Proteasome; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome; Ubiquitination
	Nateglinide (Senaglinide) 是 D-苯丙氨酸的一种衍生物，是口服有效的、短效促胰岛素释放化合物，也是 DPP IV 抑制剂。 Nateglinide 抑制胰岛 β 细胞中 ATP 敏感的 K+通道。Nateglinide 在 2 型糖尿病中具有研究价值。
T0331	Moxifloxacin hydrochloride 盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Moxifloxacin hydrochloride (BAY12-8039 HCl) 是一种口服有效的 8-甲氧基喹诺酮类抗菌药物，可研究感染性肺炎，急性细菌性鼻窦炎和慢性支气管炎的急性细菌性加重。
T0078L	Lapatinib ditosylate monohydrate Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,二甲苯磺酸拉帕替尼单水合物,Tyverb	EGFR; Ferroptosis; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Lapatinib ditosylate (Lapatinib tosilate) monohydrate 是一种有效的 EGFR 和 ErbB2 抑制剂，对 EGFR 和 ErbB2的 IC50值分别为 10.8 和 9.2 nM。它用于治疗晚期乳腺癌和其他实体瘤。
T0137	Mirtazapine 米氮平,6-Azamianserin,Org3770	Dopamine Receptor; 5-HT Receptor; Opioid Receptor; Adrenergic Receptor; Histamine Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Mirtazapine (6-Azamianserin) 是一种有效的具有口服活性的去甲肾上腺素能和特异性血清素能抗抑郁剂 (NaSSA)。它也是一种5-HT2、5-HT3、组胺 H1 受体和 α2-肾上腺素受体拮抗剂，pKi 值分别为 8.05、8.1、9.3 和 6.95。
T4297	Flibanserin BIMT-17BS,氟立班丝氨,Girosa,BIMT-17	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Flibanserin (Girosa) 一种具有口服活性的 5-HT1A 受体激动剂和 5-HT2A 受体拮抗剂，Ki 值分别为 1 和 49 nM。它与多巴胺 D4 受体结合，Ki 值在 4 到 24 nM 之间。它是一种血清素能抗抑郁药，用于治疗性欲减退症。
T1476	Pramipexole SND 919,普拉克索	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Pramipexole (SND 919) 是能够透过血脑屏障的 D2 型多巴胺受体的选择性激动剂，对 D2 型受体、D2、D3、D4亚型受体的Ki 分别为 2.2 nM、3.9 nM、0.5 nM、1.3 nM。它可用于研究帕金森综合症和腿多动综合征。
T1951	Asenapine Maleate Org 5222 maleate,Org 5222,马来酸阿塞那平,阿塞那平马来酸盐	5-HT Receptor	GPCR/G Protein; Neuroscience
	Asenapine Maleate (Org 5222 maleate) 是5-HT 和D2的拮抗剂，Ki 值分别为 0.03-4.0 nM, 1.3 nM。它也是抗精神病药物，用于治疗与双相 1 型障碍相关的精神分裂症和躁狂或混合发作。
T0189L	Pemetrexed disodium 培美曲塞二钠盐,LY-231514,LY231514 disodium,培美曲塞二钠,Pemetrexed	Apoptosis; DHFR; DNA/RNA Synthesis; Antifolate; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Pemetrexed disodium (LY-231514) 是一种叶酸拮抗剂，用于治疗非小细胞肺癌和恶性间皮瘤。它抑制胸苷酸合成酶，二氢叶酸还原酶和甘氨酰胺核苷酸甲酰转移酶的Ki 分别为 1.3 nM，7.2 nM 和 65 nM。
T1786	Daclatasvir dihydrochloride BMS-790052 dihydrochloride,盐酸达拉他韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) 是有机阴离子转运多肽 1B(OATP1B) 和 OATP1B3抑制剂，IC50分别为 1.5 µM 和 3.27 µM。它也具有口服活性的 HCV NS5A 蛋白抑制剂，多种 HCV 复制子基因型的 EC50范围为 9-146 pM。
T72039	CLK1-IN-3	DYRK; CDK; Autophagy	Autophagy; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
	CLK1-IN-3 是一种+具有选择性和高效的性 Clk1 抑制剂，其 IC50 为 5 nM，比对 Dyrk1A 的亲和力高300对倍。CLK1-IN-3 对 Clk2 和 Clk4 也显示出高效的抑制作用，IC50 值分别为 42 和 108 nM。CLK1-IN-3 在体外有效诱导自噬 (autophagy)，可用于预防和人治疗急性肝损伤 (ALI)。
T0371L	Gliquidone sodium	Others	Others
	Gliquidone sodium is a hypoglycemic sulfonylurea which may protect the liver from injury from diabetes.
T36509	U-74389G U-74389G,Methylated Tirilazad	Others	Others
	U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]
T69218	PUMAi HCl	Others	Others
	PUMAi is an inhibitor of p53 up-regulated modulator of apoptosis (PUMA), a BH3-only Bcl-2 family member, mitigating acetaminophen (APAP)-induced hepatocyte necrosis and liver injury.
T61599	XT2	Others	Others
	XT2 is a highly potent, orally active, and selective inhibitor of NF-κB-inducing kinase (NIK), exhibiting an IC50 of 9.1 nM. It effectively suppresses the upregulation of ALT, a vital biomarker for acute liver injury, induced by CCl4. Additionally, XT2 significantly decreases immune cell infiltration into the damaged liver tissue. As a result, XT2 holds immense potential in liver inflammatory disease research [1].
T69724	Cilofexor tromethamine	Others	Others
	Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.
T69962	IDN-1965	Others	Others
	IDN-1965 is a potent, broad-spectrum, irreversible caspase inhibitor. IDN-1965 is markedly effective at inhibiting Fas-mediated apoptosis by multiple routes of administration. The therapeutic potential of caspase inhibitors appears promising for the treatment of apoptosis-mediated liver injury based on potency and postinsult efficacy.
T11752	Keap1-Nrf2-IN-1 Keap1–Nrf2-IN-1	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	Keap1–Nrf2 IN-1 activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models. Keap1–Nrf2 IN-1 is a Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (
T1503	Esmolol hydrochloride ASL8052,Esmolol HCl,盐酸艾司洛尔	Mitophagy; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Esmolol hydrochloride 是一种心脏选择性β受体阻滞剂，用于治疗心律失常和严重高血压。
T37842	ASB 14780	Others	Others
	Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor (IC50 = 20 nM). Selective for cPLA2α over secreted PLA2α (sPLA2α; exhibits no inhibition at 10 μM). Inhibits cPLA2α-dependent inflammatory responses in vitro in guinea pig and human whole-blood assays. Improves diet-induced liver injury and CCl4-induced hepatic fibrosis in vivo. Orally bioavailable.

化合物

Cat.No: T1677

Synonym: 孟鲁司特,Singular

Target: Leukotriene Receptor, Lipoxygenase, LTR

Montelukast sodium

Cat.No: T1677L

Synonym: MK0476,孟鲁司特钠

Target: Leukotriene Receptor, LTR

Enoxaparin sodium

Cat.No: T22323

Target: Thrombin

Cat.No: T2171

Synonym: SEW2871

Target: S1P Receptor, LPL Receptor

Cat.No: T1090

Synonym: Perphenazin,Etaperazine,Trilafon,奋乃静

Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Cat.No: T14491

Target: NF-κB

Cat.No: T69360

Target: Prostaglandin Receptor

Cat.No: T7045

Synonym: Nexiclon,Catapres,Kapvay,可乐定

Target: Adrenergic Receptor

Cat.No: T11747

Target: PPAR

Cat.No: T31795

Synonym: LS-192510,FR-260330,FK330,FK 330

Target: NOS

mPGES-1 Inhibitor-1

Cat.No: T28089

Target: Prostaglandin Receptor

Aclidinium bromide

Cat.No: T2555

Synonym: LAS 34273,LAS-W 330,阿地溴铵

Target: AChR

Betaxolol hydrochloride

Cat.No: T0226

Synonym: 盐酸倍他洛尔,SL75212,SL 75212 HCl,Betaxolol HCl

Target: Adrenergic Receptor

Trospium chloride

Cat.No: T1472

Synonym: Spasmex,Sanctura,曲司氯铵,曲司氯胺

Target: AChR

Cat.No: T37859

Target: Endogenous Metabolite

Cat.No: T17018

Target: BCL

Cat.No: T1655

Synonym: BSF-208075,BSF 208075,安倍生坦,LU 208075

Target: Endothelin Receptor

Cat.No: T7280

Target: Phospholipase

Cat.No: T0085L

Synonym: BMS200475,SQ34676,恩替卡韦

Target: HBV

Cat.No: T73446

Target: Dehydrogenase

Cat.No: T1088

Synonym: AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈

Target: Potassium Channel, PPAR

Quinapril hydrochloride

Cat.No: T0805

Synonym: CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl

Target: RAAS

Benazepril hydrochloride

Cat.No: T0180

Synonym: 盐酸贝那普利,CGS 14824A HCl,Benazepril HCl,CGS14824A

Target: RAAS

Docusate sodium

Cat.No: T0929

Synonym: Aerosol OT,多库脂钠,Dioctyl sulfosuccinate sodium salt,Bis(2-ethylhexyl) sulfosuccinate sodium salt,Constonate

Target: Opioid Receptor, HSV

FK-330 dihydrate

Cat.No: T68879

Synonym: FR-260330 dihydrate

Target: NO Synthase

Cat.No: T6875

Synonym: RDEA594,雷西那德,来司诺雷

Target: OAT

Cat.No: T0214

Synonym: U 72107,吡格列酮,匹格列酮

Target: Ferroptosis, PPAR

Ono-3307 mesylate

Cat.No: T28248

Synonym: Ono-3307,Ono3307,Ono 3307

Target: Protease

Cat.No: T16376

Synonym: A4250

Target: Others

Cat.No: T6647

Synonym: Neupro,N-0923,罗替戈汀,N-0437,SPM 962

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Milnacipran hydrochloride

Cat.No: T1189

Synonym: 盐酸米那普仑,Milnacipran HCl,Savella,Dalcipran

Target: Serotonin Transporter, Norepinephrine

Cat.No: T1674

Synonym: 那格列奈,A4166,Senaglinide

Target: Potassium Channel, Proteasome, PPAR

Moxifloxacin hydrochloride

Cat.No: T0331

Synonym: 盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl

Target: Topoisomerase, Antibacterial, Antibiotic

Lapatinib ditosylate monohydrate

Cat.No: T0078L

Synonym: Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,二甲苯磺酸拉帕替尼单水合物,Tyverb

Target: EGFR, Ferroptosis, Autophagy

Cat.No: T0137

Synonym: 米氮平,6-Azamianserin,Org3770

Target: Dopamine Receptor, 5-HT Receptor, Opioid Receptor, Adrenergic Receptor, Histamine Receptor

Cat.No: T4297

Synonym: BIMT-17BS,氟立班丝氨,Girosa,BIMT-17

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T1476

Synonym: SND 919,普拉克索

Target: Dopamine Receptor

Asenapine Maleate

Cat.No: T1951

Synonym: Org 5222 maleate,Org 5222,马来酸阿塞那平,阿塞那平马来酸盐

Target: 5-HT Receptor

Pemetrexed disodium

Cat.No: T0189L

Synonym: 培美曲塞二钠盐,LY-231514,LY231514 disodium,培美曲塞二钠,Pemetrexed

Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Daclatasvir dihydrochloride

Cat.No: T1786

Synonym: BMS-790052 dihydrochloride,盐酸达拉他韦

Target: HCV Protease

Cat.No: T72039

Target: DYRK, CDK, Autophagy

Gliquidone sodium

Cat.No: T0371L

Target: Others

Cat.No: T36509

Synonym: U-74389G,Methylated Tirilazad

Target: Others

Cat.No: T69218

Target: Others

Cat.No: T61599

Target: Others

Cilofexor tromethamine

Cat.No: T69724

Target: Others

Cat.No: T69962

Target: Others

Keap1-Nrf2-IN-1

Cat.No: T11752

Synonym: Keap1–Nrf2-IN-1

Target: Src

Esmolol hydrochloride

Cat.No: T1503

Synonym: ASL8052,Esmolol HCl,盐酸艾司洛尔

Target: Mitophagy, Adrenergic Receptor, Autophagy

Cat.No: T37842

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T8733	Antrodin A (2-氯苯基)二苯基甲醇,camphorataanhydride A	Others	Others
	Antrodin A (camphorataanhydride A) 是固体发酵樟脑菌菌丝体的一种主要活性成分。它能够增强肝脏的抗炎及抗氧化能力，维持肠道菌群的稳定，避免酒精对肝脏的损伤。
TN1143	1-O-Acetyl britannilactone	Apoptosis; Antibiotic	Apoptosis; Microbiology/Virology
	1-O-Acetyl britannilactone 是一种农用杀菌剂，可诱导细胞凋亡，可用于研究肝损伤和癌症。
TN4661	Nodosin	IL Receptor; Autophagy	Autophagy; Immunology/Inflammation
	Nodosin 是一种二萜化合物，从Isodon trichocarpusKudo 和I. JaponicusHARA 中提取得到。
T3273	Bifendate 联苯双酯,Bifendatatum	HBV; Reverse Transcriptase	Microbiology/Virology
	Bifendate (Bifendatatum) 是 Schisandrin C 的合成中间体，在慢性 B 型肝炎的研究中具有抗HBV 功效，用于治疗病毒性肝炎和药物性肝损伤引起的转氨酶升高。
TN1132	Procyanidin A2 原花青素 A2,原花青素A2	IL Receptor; TNF; transporter; Antibacterial	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Procyanidin A2 是一种具有抗癌、抗氧化、抗菌和抗炎活性的黄酮类天然产物，存在于蔓越莓和越橘中。
T3S0289	Araloside X	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi
T3779	Crocin II Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B	Caspase; COX; NO Synthase	Apoptosis; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
	Crocin II (Crocetin gentiobiosylglucosyl ester) 是从栀子果实中分离出来的一种天然产物，具有抗氧化、抗癌和抗抑郁活性。它抑制 iNOS 和 COX-2的蛋白质和 m-RNA 的表达，还抑制NO 产生，IC50值为 31.1 μM。
T6194	Fidaxomicin 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Fidaxomicin (Tiacumicin B) 是一种大环RNA 聚合酶抑制剂，具有窄谱活性。它选择性地根除致病性艰难梭菌，对构成正常健康肠道菌群的多种细菌影响很小。
T3674	Hydroxysafflor yellow A 藏红花,羟基红花黄色素A,HSYA,Safflomin A	TGF-beta/Smad	Stem Cells
	Hydroxysafflor yellow A (Safflomin A) 是一种黄酮类天然产物，从中药红花中分离得到，具有抗癌作用。
T15245	Erythromycin estolate Phtalic anhydride,ilosone	Antibacterial	Microbiology/Virology
	Erythromycin estolate 是红霉素的衍生物，属于大环内酯类抗生素，常用于研究多种细菌感染。酯酸红霉素对胆汁酸转运有抑制作用，可引起肝损伤，主要是胆汁淤积性肝炎。
T0224	Meropenem 美罗培南,SM 7338	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Meropenem (SM 7338) 是一种具有广谱抗菌活性的碳青霉烯抗生素，对敏感和耐药的淋病奈瑟氏球菌，流感嗜血杆菌和杜克氏杆菌的 MIC 值分别为 0.02-0.06 mg/mL，0.03-0.12 mg/mL 和 0.015-0.12 mg/mL。
TN1464	Camellianin A	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Camellianin A 是从 A. nitida 和茶叶中提取得到的类黄酮列化合物，具有抗癌活性，抑制血管紧张素转换酶 (ACE) 活性，促进 Hep G2 和 MCF-7 细胞凋亡。Camellianin A 可预防CCl4-通过施加抗氧化应激、抗炎和抗细胞凋亡诱导肝损伤。
TN5770	Gingerenone A	Nrf2	Immunology/Inflammation
	Gingerenone A 是一种有效的 Nrf2-Gpx4 激活剂，是从生姜里面分离出来的小分子化合物，具有抗癌活性，可延长癌细胞的细胞周期，可抑制右旋糖酐硫酸钠 (DSS) 诱导的结肠炎小鼠继发性肝损伤 (SLI) 中的铁死亡。
T6S0653	Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷	TNF; AChE	Apoptosis; Neuroscience
	Linarin (Acacetin-7-O-rutinoside) 是一种选择性的乙酰胆碱酯酶 (AChE) 抑制剂，从薄荷花提取物中分离得到。
T2175	Apigenin C.I. Natural Yellow 1,4',5,7-Trihydroxyflavone,NSC 83244,金银花,Apigenol,芹菜素,LY 080400	P450; Autophagy	Autophagy; Metabolism
	Apigenin (LY 080400) 属于黄酮类天然产物，是一种 CYP2C9 抑制剂 (Ki=2 μM)，具有竞争性。Apigenin 可以减少焦虑，影响免疫健康，调节激素，被用作镇静剂、温和的镇痛剂和安眠剂。
T6S1572	Sauchinone	ERK; p38 MAPK; NF-κB	MAPK; NF-κB
	Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS，TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
T4S2326	Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside	ERK; p38 MAPK; NF-κB; JNK	MAPK; NF-κB
	Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷，可用于炎症疾病的研究和促进血液循环。它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应，用于炎性过敏性疾病中的潜能。
T2S2264	Linalool Linalol,(±)-Linalool,Phantol,沉香醇	Apoptosis; IL Receptor; TNF; Endogenous Metabolite; iGluR	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA 受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。
T4S0797	Berberine 小檗碱,Berberin,Umbellatine,黄连素	Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Berberine (Umbellatine) 属于生物碱类天然产物，可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。
T6677	Sophocarpine	ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长，具有抗肿瘤活性。
T31134	Cyclochlorotine CCRIS 1316
	Cyclochlorotine is a mycotoxin produced by Penicillium insularum, which can cause liver injury and has carcinogenic properties.
TN3517	Bisacurone	IL Receptor; IκB/IKK; TNF; NF-κB; ROS; Akt; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
	Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressing hepatic oxidation and inflammation.
TN3107	5-Deoxystrigol	Others	Others
	5-Deoxystrigol 是一种高活性的独脚金发芽刺激剂。对 D-半乳糖胺（D-GalN）诱导的小鼠急性肝损伤有保护作用，对 CCl4诱导的小鼠急性肝损伤有保护作用。
TN2147	Retrorsine	P450; OCT	Membrane transporter/Ion channel; Metabolism
	Retrorsine 特异性地抑制肝细胞增殖，并在肝损伤后唤起小肝细胞样祖细胞。逆转录酶可用于肝细胞损伤的研究。
T83371	3,4-Didehydroglabridin
	3,4-Didehydroglabridin 是甘草中的天然产物，具有对四氯化碳诱导的 HepG2 细胞损伤的保护作用，展现出在肝损伤研究中的应用潜力。
T81411	Praeroside IV
	Praeroside IV，一种可从当归根中提取的化合物，常用于研究D-GalN/LPS诱导的肝损伤。
TN4291	Isofuranodiene	IL Receptor; NOS	Immunology/Inflammation
	Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apo
TN4374	Kaerophyllin (-)-Kaerophylin	Apoptosis	Apoptosis
	Kaerophyllin ( (-)-Kaerophylin) 是一种从中药柴胡中分离出的木酚素，抑制肝细胞凋亡小体激活肝星状细胞，通过抑制肝脏炎症和抑制 HSC 活化来保护大鼠肝脏免受 TAA 引起的损伤和纤维化。
T82365	Fulvotomentoside B
	Fulvotomentoside B, 一种可从黄毛乳杆菌中分离的皂苷，对于CCl4、d-gal 和对乙酰氨基酚所致中毒小鼠具有显著的保护作用。在减低血清SGPT和GT水平以及减轻肝脏病理损伤方面表现出突出的效果。
T35624	Ajoene	Others	Others
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Cat.No: T8733

Synonym: (2-氯苯基)二苯基甲醇,camphorataanhydride A

Target: Others

1-O-Acetyl britannilactone

Cat.No: TN1143

Target: Apoptosis, Antibiotic

Cat.No: TN4661

Target: IL Receptor, Autophagy

Cat.No: T3273

Synonym: 联苯双酯,Bifendatatum

Target: HBV, Reverse Transcriptase

Cat.No: TN1132

Synonym: 原花青素 A2,原花青素A2

Target: IL Receptor, TNF, transporter, Antibacterial

Cat.No: T3S0289

Target: Calcium Channel

Cat.No: T3779

Synonym: Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

Cat.No: T6194

Synonym: 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

Hydroxysafflor yellow A

Cat.No: T3674

Synonym: 藏红花,羟基红花黄色素A,HSYA,Safflomin A

Target: TGF-beta/Smad

Erythromycin estolate

Cat.No: T15245

Synonym: Phtalic anhydride,ilosone

Target: Antibacterial

Cat.No: T0224

Synonym: 美罗培南,SM 7338

Target: Others, Antibacterial, Antibiotic

Cat.No: TN1464

Target: Apoptosis, RAAS

Cat.No: TN5770

Target: Nrf2

Cat.No: T6S0653

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷

Target: TNF, AChE

Cat.No: T2175

Synonym: C.I. Natural Yellow 1,4',5,7-Trihydroxyflavone,NSC 83244,金银花,Apigenol,芹菜素,LY 080400

Target: P450, Autophagy

Cat.No: T6S1572

Target: ERK, p38 MAPK, NF-κB

Cat.No: T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

Cat.No: T2S2264

Synonym: Linalol,(±)-Linalool,Phantol,沉香醇

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Cat.No: T4S0797

Synonym: 小檗碱,Berberin,Umbellatine,黄连素

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Cat.No: T6677

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Cyclochlorotine

Cat.No: T31134

Synonym: CCRIS 1316

Cat.No: TN3517

Target: IL Receptor, IκB/IKK, TNF, NF-κB, ROS, Akt, PKC

Cat.No: TN3107

Target: Others

Cat.No: TN2147

Target: P450, OCT

3,4-Didehydroglabridin

Cat.No: T83371

Cat.No: T81411

Cat.No: TN4291

Target: IL Receptor, NOS

Cat.No: TN4374

Synonym: (-)-Kaerophylin

Target: Apoptosis

Fulvotomentoside B

Cat.No: T82365

Cat.No: T35624

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain) HME,ME,MMP-12,MME,matrix metallopeptidase 12	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His) coagulation factor 11,coagulation factor XI,FXI	Human	HEK293 Cells
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ...
TMPY-01099	GPT Protein, Rat, Recombinant (His) Gpt1,ALAT,glutamic-pyruvate transaminase (alanine aminotrans...	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc...
TMPJ-00876	FAH Protein, Human, Recombinant (His) Fumarylacetoacetate Hydrolase,β-Diketonase,FAH,FAA,Fumarylac...	Human	HEK293 Cells
	Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. Defects in Fumarylacetoacetase cause tyrosinemia type 1, which is congenital metabolism defect characterized by elevated levels of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include renal tubular injury, self-mutilation, hepatic necrosis, ep...
TMPH-01796	NR4A1 Protein, Human, Recombinant (His & Myc) ST-59,NR4A1,Nuclear hormone receptor NUR/77,Orphan nuclear r...	Human	E. coli
	Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury. NR4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expre...
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPY-01100	GPT2 Protein, Rat, Recombinant (His) glutamic pyruvate transaminase (alanine aminotransferase) 2	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share ...
TMPY-01770	HAO1 Protein, Human, Recombinant (His) GOX1,hydroxyacid oxidase (glycolate oxidase) 1,GOX,HAOX1	Human	E. coli
	Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. HAO1 / GOX1 is a liver-specific peroxisomal enzyme that oxidizes glycolate to glyoxylate with the concomitant production of H2O2. In H...
TMPY-02014	Coagulation factor VII/F7 Protein, Human, Recombinant (His) coagulation factor VII (serum prothrombin conversion acceler...	Human	HEK293 Cells
	Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is ...

重组蛋白

MMP-12 Protein, Human, Recombinant (catalytic domain)

Cat.No: TMPY-02869

Species: Human

Expression System: E. coli

Coagulation factor XI/F11 Protein, Human, Recombinant (His)

Cat.No: TMPY-01104

Species: Human

Expression System: HEK293 Cells

GPT Protein, Rat, Recombinant (His)

Cat.No: TMPY-01099

Species: Rat

Expression System: Baculovirus Insect Cells

FAH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00876

Species: Human

Expression System: HEK293 Cells

NR4A1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01796

Species: Human

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

GPT2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-01100

Species: Rat

Expression System: Baculovirus Insect Cells

HAO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01770

Species: Human

Expression System: E. coli

Coagulation factor VII/F7 Protein, Human, Recombinant (His)

Cat.No: TMPY-02014

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0198	Esmolol-d7 HCl
	Esmolol-d7 HCl 是 Esmolol HCl 的氘代化合物。Esmolol HCl 的 CAS 号为 81161-17-3。Esmolol hydrochloride 是一种心脏选择性β受体阻滞剂，用于治疗心律失常和严重高血压。
TMIJ-0253	Benazepril-d5 HCl
	Benazepril-d5 HCl 是 Benazepril HCl 的氘代化合物。Benazepril HCl 的 CAS 号为 86541-74-4。Benazepril hydrochloride 是一种血管紧张素转化酶（ACE）抑制剂，能够作用于高血压。
TMID-0126	Clonidine-d4 Hydrochloride
	Clonidine-d4 Hydrochloride 是 Clonidine Hydrochloride 的氘代化合物。Clonidine Hydrochloride 的 CAS 号为 4205-91-8。Clonidine hydrochloride 是一种α2-adrenoceptor激动剂，是一种抗高血压药。
TMIJ-0329	Montelukast-d6
	Montelukast-d6 是 Montelukast 的氘代化合物。Montelukast 的 CAS 号为 158966-92-8。Montelukast 是可口服的半胱氨酸白三烯受体1 选择性拮抗剂，可用于研究预防哮喘和肝损伤。它还可减少心脏损伤，在肠缺血-再灌注损伤中也具有抗氧化作用。
TMIJ-0136	Moxifloxacin-d4 HCl
	Moxifloxacin-d4 HCl 是 Moxifloxacin HCl 的氘代化合物。Moxifloxacin HCl 的 CAS 号为 186826-86-8。Moxifloxacin Hydrochloride是一种口服有效的 8-甲氧基喹诺酮类抗菌药物，可研究感染性肺炎，急性细菌性鼻窦炎和慢性支气管炎的急性细菌性加重。
TMIH-0095	Apigenin-d4
	Apigenin-d4 是 Apigenin 的氘代化合物。Apigenin 的 CAS 号为 520-36-5。Apigenin 是从韩信草中提取的一种天然产物，是一种竞争性CYP2C9抑制剂，Ki为 2 μM。它被用作镇静剂、温和的镇痛剂和安眠药。
TMIH-0096	Apigenin-d6
	Apigenin-d6 是 Apigenin 的氘代化合物。Apigenin 的 CAS 号为 520-36-5。Apigenin 是从韩信草中提取的一种天然产物，是一种竞争性CYP2C9抑制剂，Ki为 2 μM。它被用作镇静剂、温和的镇痛剂和安眠药。
TMIJ-0287	Meropenem-d6-1
	Meropenem-d6-1 是 Meropenem-1 的氘代化合物。Meropenem-1 的 CAS 号为 96036-03-2。Meropenem是一种具有广谱抗菌活性的碳青霉烯抗生素，对敏感和耐药的淋病奈瑟氏球菌，流感嗜血杆菌和杜克氏杆菌的 MIC 值分别为 0.02-0.06 mg/mL，0.03-0.12 mg/mL 和 0.015-0.12 mg/mL。
TMID-0190	Milnacipran-d10 Hydrochloride
	Milnacipran-d10 Hydrochloride 是 Milnacipran Hydrochloride 的氘代化合物。Milnacipran Hydrochloride 的 CAS 号为 101152-94-7。Milnacipran hydrochloride 是一种5-羟色胺-去甲肾上腺素重吸收抑制剂（SNRI），可用于纤维肌痛的研究。
TMID-0254	Linalool-d3
	Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。

同位素标记化合物

Cat.No: TMID-0198

Benazepril-d5 HCl

Cat.No: TMIJ-0253

Clonidine-d4 Hydrochloride

Cat.No: TMID-0126

Cat.No: TMIJ-0329

Moxifloxacin-d4 HCl

Cat.No: TMIJ-0136

Cat.No: TMIH-0095

Cat.No: TMIH-0096

Cat.No: TMIJ-0287

Milnacipran-d10 Hydrochloride

Cat.No: TMID-0190

Cat.No: TMID-0254

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼