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Search Results for " hematopoietic "

Targets Recommended: Glucokinase Autophagy

72

抑制剂 & 化合物

3

天然产物

2

化合物库

100

重组蛋白

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Cat. No.	Product Name
L3100	造血毒性小分子库		101 compounds
	101 种生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2140	癌细胞分化化合物库		406 compounds
	406 个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

造血毒性小分子库

Cat.No: L3100

Compounds: 101

癌细胞分化化合物库

Cat.No: L2140

Compounds: 406

Cat. No.	Product Name	Target	Signaling Pathways
T22223	3PO	Glucokinase; Autophagy	Autophagy; Metabolism
	3PO 是一种 PFKFB3 的小分子抑制剂，IC50值为22.9 μM。它抑制几种人类恶性造血和腺癌细胞系的增殖，IC50在1.4到24 μM 之间。它抑制葡萄糖摄取，并降低 Fru-2,6-BP、乳酸、ATP、NAD+ 和 NADH 的细胞内浓度。
T2121	SW033291	Dehydrogenase	Metabolism
	SW033291 是有效的15-PGDH 抑制剂，与15-PGDH 亲和力高，Ki 为 0.1 nM。它增加骨髓和其他组织中前列腺素 PGE2 的水平。它还可促进组织再生。
T11438	GNE-1858	Others; MAPK	MAPK; Others
	GNE-1858 是高效的 ATP 竞争性造血祖细胞激酶-1抑制剂，能够抑制野生型(IC50:1.9 nM)、活性模拟突变株 HPK1-TSEE (IC50:1.9 nM)、 HPK1-SA (IC50:4.5 nM)的活性。
T3590	NSC23005	CDK	Cell Cycle/Checkpoint
	NSC23005 是一种 p18INK 抑制剂，可有效促进造血干细胞 (HSC) 扩增 (ED50: 5.21 nM)。
T1776L	Plerixafor octahydrochloride 盐酸普乐沙福,JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl	Virus Protease; HIV Protease; CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Plerixafor octahydrochloride (JM3100 octahydrochloride) 是一种选择性的CXCR4拮抗剂，IC50为 44 nM。Plerixafor 是一种具有造血干细胞动员活性的双环霉素。
T8883	Pizuglanstat	Others; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Others
	Pizuglanstat 是一种前列腺素 D 合酶抑制剂，对人造血前列腺素 D 合酶的IC50为 76 nM，可用于肌再生性疾病研究。
T24580	P18IN003 P18IN 003,P18IN-003	CDK	Cell Cycle/Checkpoint
	P18IN003 是一种具有选择性和有效性的 p18(INK4C) 抑制剂，可抑制 p18 蛋白的活性可用于研究造血干细胞的体外扩增。
T7948	HPGDS inhibitor 2 GSK-2894631A	PGE Synthase	Immunology/Inflammation
	HPGDS inhibitor 2 (GSK-2894631A) 是高效的造血前列腺素 D 合成酶(H-PGDS)选择性抑制剂(IC50:9.9 nM)。
T16699	PYZD-4409	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	PYZD-4409 是一种特异性 UBA1 抑制剂，IC50 为 20 μM。 PYZD-4409 在恶性细胞中诱导细胞死亡，并且对恶性细胞的细胞毒性优于对正常造血细胞的细胞毒性。
T3589	NSC23005 Sodium	CDK	Cell Cycle/Checkpoint
	NSC23005 sodium 是新型 p18 抑制剂 (ED50=5.21 nM)，在小鼠和人类模型中促进造血干细胞扩增。
T69730	F092	PGE Synthase	Immunology/Inflammation
	F092 是一种高效的造血前列腺素 D 合成酶 (H-PGDS) 抑制剂，可以用于研究过敏性炎症和与血管相关的疾病。
T21785	AG957	Bcr-Abl	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Tyrphostin AG957 是一种酪氨酸激酶抑制剂，具有抗BCR/ABL 酪氨酸激酶活性。它能够抑制p210bcr/abl 酶活性 (IC50:2.9 μM)。
T1804	HPGDS inhibitor 1 HPGDS-inhibitor-1	PGE Synthase	Immunology/Inflammation
	HPGDS inhibitor 1 是口服具有活性的HPGDS 选择性抑制剂，在酶和细胞分析中的IC50值分别为 0.6 nM 和 32 nM，但对 L-PGDS、mPGES、COX-1、COX-2 、5-LOX 无抑制作用。
T60081	BV02 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid	Others	Others
	BV02 是 14-3-3 蛋白-蛋白相互作用的抑制剂，可用于治疗慢性粒细胞白血病的研究。 BV02 破坏表达 IM 抗性 T315I 突变和 IM 敏感的野生型 Bcr-Abl 的造血细胞。
T11053	DJ001	Phosphatase	Metabolism
	DJ001 是一种高度特异性，选择性和非竞争性的蛋白酪氨酸磷酸酶-σ (PTPσ) 抑制剂，IC50 为 1.43 μM。DJ001 对其他磷酸酶无抑制活性，对蛋白质磷酸酶 5 仅有中等抑制活性。DJ001 促进造血干细胞再生。
T9017	HPK1-IN-2 Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2	Others; FLT; Src	Angiogenesis; Others; Tyrosine Kinase/Adaptors
	HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) 是一种有效且具有口服活性的造血祖细胞激酶-1 抑制剂(HPK1；IC50<0.05 µM)。它还抑制 Lck (0.05 µM<IC50<0.5 µM) 和 Flt3 (IC50<0.05 µM) 激酶活性，具有抗肿瘤活性。
T76870	Narsoplimab OMS 721	SARS-CoV	Microbiology/Virology
	Narsoplimab (OMS 721) 是一种选择性全人免疫球蛋白γ 4 (IgG4) 单克隆抗体，是一种甘露聚糖结合凝集素相关的丝氨酸蛋白酶-2（MASP-2）抑制剂，可结合 MASP-2 并阻止凝集素通路激活，对凝集素通路有抑制作用。Narsoplimab 可用于研究成人造血干细胞移植相关疾病。
T22070	DBIBB	LPA Receptor	GPCR/G Protein
	DBIBB 是一种特异性溶血磷脂酸 (LPA2) 的 2 型 G 蛋白偶联受体的非脂质激动剂，是一种能够治疗高强度γ 射线对造血和胃肠系统引起的急性放射综合征的潜在活性分子，是一种作未有机合成和药物研究中的中间体。 DBIBB 可用于制备各种化合物，可减轻胃肠道辐射综合征，增加肠隐窝存活率和肠细胞增殖，并减少细胞凋亡。
T21493	Cyclosporin H	Others	Others
	Cyclosporin H 是一种 FPR-1(甲酰肽受体 1) 的选择性强效抑制剂。它缺乏 Cyclosporin A 具有的免疫抑制活性。它是一种病毒转导增强剂，可使人脐带血来源的造血干细胞和祖细胞中慢病毒转导增强 10 倍。它与雷帕霉素或前列腺素 E2 联合使用时表现出累加效应。
T24870	TFC-007 TFC007	Others	Others
	TFC-007 is an inhibitor of hematopoietic prostaglandin D synthase.
T39709	HPK1-IN-19 HPK1-IN-19	Others	Others
	HPK1-IN-19 is an inhibitor of hematopoietic progenitor kinase 1 (HPK1).
T40188	HPK1-IN-20 HPK1-IN-20	Others	Others
	HPK1-IN-19 is a potent inhibitor of hematopoietic progenitor kinase 1 (HPK1).
T26887	BOP	Others	Others
	BOP is anantagonist of alpha4beta1/alpha9beta1 integrins. BOP rapidly mobilizes long-term multi-lineage reconstituting hematopoietic stem cells (HSC).
TP2339	Goralatide
	Goralatide, isolated from fetal calf bone marrow, exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells.
T29166	XIE18-6 XIE186	Others	Others
	XIE18-6, a novel INK4C inhibitor, specifically blocks the bioactivity of p18 protein and promotes human and murine hematopoietic stem cell ex vivo expansion.
T27591	II-B08 II-B 08,FAP1 Inhibitor,II-B-08,LMWPTP Inhibitor,Lyp Inhibitor III,CD45 Inhibitor V	Others	Others
	II-B08 is a cell-permeable SHP2 inhibitor (IC50 = 5.5 µM). II-B08 blocks growth factor stimulated ERK1/2 activation and hematopoietic progenitor proliferation.
T10046	16,16-Dimethyl prostaglandin E2 16,16-dimethyl PGE2	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
T72036	HPK1-IN-36	Others	Others
	HPK1-IN-36（compound 2）作为一种HPK1抑制剂，表现出高效性，其IC50为0.5 nM。
T84924	PROTAC(H-PGDS)-8	Others	Others
	PROTAC(H-PGDS)-8，一种针对造血前列腺素D合酶 (H-PGDS) 的PROTAC降解剂，具有 0.14 μM 的IC50值。
T77993	Goralatide acetate
	Goralatide为一种内源性四肽，作为造血生理调节剂。该化合物能够抑制原始造血细胞的增殖。
T37603	Osteogenic Growth Peptide (10-14)
	YGFGG, C-terminal pentapeptide fragment of the osteogenic growth peptide (OGP), (H-8640), showed the full spectrum of OGP-like bioactivities. It has attracted considerable interest as bone anabolic agent and hematopoietic stimulator.
T72052	HPK1-IN-34	Others	Others
	HPK1-IN-34是一种造血祖细胞激酶1(HPK1)抑制剂，IC50<100nM。
T33267	Me6TREN 4HCl Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl	Others	Others
	Me6TREN 4HCl is a potent and efficacious mobilizing agent of hematopoietic stem and progenitor cells (HSPCs) that can act by activating MMP-9 expression and disrupting the SDF-1α/CXCR4 axis, exhibiting more significant mobilizing effects than G-CSF or AMD
TP2141L	Balixafortide POL6326	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM and it is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects[1][2]. Balixafortide blocks β-arresti
T62859	MEIS-IN-1	Others	Others
	MEIS-IN-1 是一种有效的诱导小鼠和人类造血干细胞扩增的 MEIS 抑制剂。
T62547	HPK1-IN-17	Others	Others
	HPK1-IN-17 是一种选择性的、有效的 HPK1 抑制剂。造血祖细胞激酶1 (HPK1) 是 MAP4Ks 的家族成员，从造血祖细胞克隆。HPK1-IN-17 能够用于研究、预防或改善与 HPK1 活性相关的疾病或病症（如癌症）。
T63046	HPK1-IN-15	Others	Others
	HPK1-IN-15 是一种选择性的、有效的 HPK1 抑制剂。其中从造血祖细胞克隆的造血祖细胞激酶1 (HPK1) 属于 MAP4Ks 家族。HPK1-IN-15 能够用于与 HPK1 活性相关的疾病或病症 (如癌症) 的研究、预防或改善。
T15503	HQL-79	Others	Others
	HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-P
T13627	CP-10	CDK; PROTACs	Cell Cycle/Checkpoint; PROTAC
	CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1 nM). It inhibits the proliferation of several hematopoietic cancer cells including multiple myeloma and can degrade mutated and overexpressed CDK6.
T78852	HPK1-IN-39	Others	Others
	HPK1-IN-39（Compound 10n）为一选择性HPK1抑制剂，IC50值为29 nM。该化合物能抑制SLP76磷酸化，可用于癌症免疫治疗研究。
T60973	HPK1-IN-24	Others	Others
	HPK1-IN-24 (example 51) 可用于癌症领域研究，它是造血祖细胞激酶 1 (HPK1)的抑制剂 (Ki = 100 nM)。
T61449	HPK1-IN-18	Others	Others
	HPK1-IN-18 is a highly effective and specific HPK1 inhibitor. HPK1, a MAP kinase kinase kinase kinases (MAP4K) member, was initially isolated from hematopoietic progenitor cells. This compound, known as HPK1-IN-18, is valuable for investigating, preventing, or managing diseases or conditions linked to HPK1 activity, such as cancer[1].
T61733	HPK1-IN-25	Others	Others
	HPK1-IN-25 (示例 94) 为一种造血祖细胞激酶1 (HPK1) 抑制剂，具有129 nM的IC50值，展现出在癌症研究中的潜力。
T63661	HF51116	Others	Others
	HF51116 是 XCR4 的有效拮抗剂。HF51116 能够显著拮抗 SDF-1α 诱导的细胞迁移、钙动员和 CXCR4 内化，并利用 CXCR4 抑制 HIV-1 感染。HF51116 对HIV-1感染、造血干细胞动员和癌症转移表现出研究潜力。
T76748	Foralumab
	Foralumab（NI-0401）为口服有效的人源化单克隆抗体，针对CD3进行靶向。其能够调控NSG小鼠体内，由人类造血干细胞重建的人类细胞的免疫反应。
T8836	CY5-SE triethylamine salt Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt)	Others	Others
	CY5-SE triethylamine salt (Fluorolink Cy5 triethanolamine salt) 是一种用于标记肽, 蛋白质, 寡核苷酸的氨基基团的反应染料 (Ex=649 nm; Em=670 nm)。
T75752	N-Acetyl-Ser-Asp-Lys-Pro acetate
	N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) acetate 是血管紧张素转换酶 (ACE) N 端活性位点的特异性底物。N-Acetyl-Ser-Asp-Lys-Pro acetate 是多能干细胞增殖的天然抑制剂。N-Acetyl-Ser-Asp-Lys-Pro acetate 具有抗炎和抗纤维化特性。
T84943	5-Androstenetriol Δ5-AT	Others	Others
	5-Androstenetriol, a steroid and active metabolite of dehydroepiandrosterone (DHEA), demonstrates significant therapeutic effects. Administered at 0.75 mg/25 g body weight, it mitigates radiation-induced mortality and facilitates hematopoietic recovery from surviving stem cells in mice. Moreover, a dosage of 40 mg/kg enhances survival rates in rats subjected to surgical trauma-induced sepsis. Additionally, elevated urinary levels of 5-androstenetriol are observed in women suffering from androgen...
T36545	Prostaglandin D2 methyl ester Prostaglandin D2 methyl ester	Others	Others
	Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.
T61250	HPGDS inhibitor 3	Others	Others
	HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally restricting H-PGDS. Moreover, HPGDS inhibitor 3 exhibits excellent selectivity with no associated central nervous system toxicity. This compound also possesses favorable pharmacokinetic properties in mouse, rat, and dog models. Additionally, HPGDS inhibitor 3 displays noteworthy an...

化合物

Cat.No: T22223

Target: Glucokinase, Autophagy

Cat.No: T2121

Target: Dehydrogenase

Cat.No: T11438

Target: Others, MAPK

Cat.No: T3590

Target: CDK

Plerixafor octahydrochloride

Cat.No: T1776L

Synonym: 盐酸普乐沙福,JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl

Target: Virus Protease, HIV Protease, CXCR

Cat.No: T8883

Target: Others, Prostaglandin Receptor

Cat.No: T24580

Synonym: P18IN 003,P18IN-003

Target: CDK

HPGDS inhibitor 2

Cat.No: T7948

Synonym: GSK-2894631A

Target: PGE Synthase

Cat.No: T16699

Target: Others, E1/E2/E3 Enzyme

NSC23005 Sodium

Cat.No: T3589

Target: CDK

Cat.No: T69730

Target: PGE Synthase

Cat.No: T21785

Target: Bcr-Abl

HPGDS inhibitor 1

Cat.No: T1804

Synonym: HPGDS-inhibitor-1

Target: PGE Synthase

Cat.No: T60081

Synonym: 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid

Target: Others

Cat.No: T11053

Target: Phosphatase

Cat.No: T9017

Synonym: Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2

Target: Others, FLT, Src

Cat.No: T76870

Synonym: OMS 721

Target: SARS-CoV

Cat.No: T22070

Target: LPA Receptor

Cat.No: T21493

Target: Others

Cat.No: T24870

Synonym: TFC007

Target: Others

Cat.No: T39709

Synonym: HPK1-IN-19

Target: Others

Cat.No: T40188

Synonym: HPK1-IN-20

Target: Others

Cat.No: T26887

Target: Others

Cat.No: TP2339

Cat.No: T29166

Synonym: XIE186

Target: Others

Cat.No: T27591

Synonym: II-B 08,FAP1 Inhibitor,II-B-08,LMWPTP Inhibitor,Lyp Inhibitor III,CD45 Inhibitor V

Target: Others

16,16-Dimethyl prostaglandin E2

Cat.No: T10046

Synonym: 16,16-dimethyl PGE2

Target: Prostaglandin Receptor

Cat.No: T72036

Target: Others

PROTAC(H-PGDS)-8

Cat.No: T84924

Target: Others

Goralatide acetate

Cat.No: T77993

Osteogenic Growth Peptide (10-14)

Cat.No: T37603

Cat.No: T72052

Target: Others

Cat.No: T33267

Synonym: Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl

Target: Others

Cat.No: TP2141L

Synonym: POL6326

Target: CXCR

Cat.No: T62859

Target: Others

Cat.No: T62547

Target: Others

Cat.No: T63046

Target: Others

Cat.No: T15503

Target: Others

Cat.No: T13627

Target: CDK, PROTACs

Cat.No: T78852

Target: Others

Cat.No: T60973

Target: Others

Cat.No: T61449

Target: Others

Cat.No: T61733

Target: Others

Cat.No: T63661

Target: Others

Cat.No: T76748

CY5-SE triethylamine salt

Cat.No: T8836

Synonym: Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt)

Target: Others

N-Acetyl-Ser-Asp-Lys-Pro acetate

Cat.No: T75752

5-Androstenetriol

Cat.No: T84943

Synonym: Δ5-AT

Target: Others

Prostaglandin D2 methyl ester

Cat.No: T36545

Synonym: Prostaglandin D2 methyl ester

Target: Others

HPGDS inhibitor 3

Cat.No: T61250

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2883	3',4'-Dimethoxyflavone	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准，类黄酮化合物具有多种药用活性。
T31836	Folate sodium Folic acid, monosodium salt,Folvite sodium
	Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
TN5094	Tangshenoside I	Glucokinase	Metabolism
	Tangshenoside I might be a potential bioactive marker related to the hematopoietic and immunologic functions of Codonopsis Radix, which could be recommended as the index compound. It has α-glucosidase inhibition activity.

天然产物

3',4'-Dimethoxyflavone

Cat.No: TN2883

Target: Others, PARP

Cat.No: T31836

Synonym: Folic acid, monosodium salt,Folvite sodium

Tangshenoside I

Cat.No: TN5094

Target: Glucokinase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00166	SCF Protein, Mouse, Recombinant SCF,Hematopoietic growth factor KL,MGF,Steel factor...	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the ...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His) Mast cell growth factor,Il3,Multipotential colony-stimulatin...	Mouse	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages.Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, bu...
TMPJ-00515	HCLS1 Protein, Human, Recombinant (His) p75,Hematopoietic cell-specific LYN substrate 1,Lck...	Human	HEK293 Cells
	Hematopoietic lineage cell-specific protein (HCLS1) is a protein that in humans is encoded by the HCLS1 gene. It is expressed only in tissues and cells of hematopoietic origin. It is substrate of the antigen receptor-coupled tyrosine kinase and plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. It may also be involved in the regulation of gene expression.
TMPY-03977	DAP10 Protein, Human, Recombinant (mFc) PIK3AP,DAP10,hematopoietic cell signal transducer,K...	Human	HEK293 Cells
	HCST (Hematopoietic Cell Signal Transducer, also known as DAP1) is a Protein Coding gene. HCST belongs to the DAP10 family. It is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. HCST may be part of the immune recognition receptor complex. This receptor plays a major role in triggering cytotoxicity against target cells expressing cell sur...
TMPJ-01393	Carboxypeptidase Q Protein, Mouse, Recombinant (His) Plasma glutamate carboxypeptidase,Hls2,Hematopoietic	Mouse	HEK293 Cells
	Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides with unsubstituted terminals into amino acids. Carboxypeptidase may play an important role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. The monomeric form is inactive while the homodimer is active.
TMPY-04077	HPGDS/PGD2 Protein, Human, Recombinant (His) hematopoietic prostaglandin D synthase,PGD2,GSTS1-1...	Human	E. coli
	HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760.
TMPJ-00894	SCF Protein, Rat, Recombinant (His) Hematopoietic growth factor KL,Steel factor,Stem ce...	Rat	E. coli
	Stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase...
TMPJ-00465	PTP1C Protein, Human, Recombinant (His) HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase...	Human	E. coli
	Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPJ-00690	PGDS Protein, Human, Recombinant Glutathione-Requiring Prostaglandin D Synthase,PGDS,Glutathi...	Human	E. coli
	Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop...
TMPJ-01470	SCF Protein, Human, Recombinant Mast Cell Growth Factor,c-Kit ligand,KITLG,MGF,Stem Cell Fac...	Human	E. coli
	Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
TMPJ-01218	M-CSF/CSF1 Protein, Rat, Recombinant CSF1,集落刺激因子,CSF-1,Macrophage colony-stimulating factor 1,M-C...	Rat	HEK293 Cells
	Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regu...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr...	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo...
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His) Erythropoietin,EPO,红细胞生长素,Epoetin	Human	HEK293 Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP...
TMPY-01280	FOLR2 Protein, Human, Recombinant (His) FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...	Human	HEK293 Cells
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Vascular endothelial growth factor receptor 1,Vascular perme...	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPH-02316	YJEFN3 Protein, Human, Recombinant YjeF N-terminal domain-containing protein 3,YJEFN3,ApoA-I-bi...	Human	E. coli
	May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progeni...
TMPK-00929	FLT3 Protein, Mouse, Recombinant (hFc) FL,FLT3LG,Flt3L,SL cytokine,Flt3 ligand	Mouse	HEK293 Cells
	Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.78 kDa and the accession number is Q00342.
TMPY-03296	SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) SH-PTP1,Hcph,70Z-SHP,Ptp1C,protein tyrosine phosphatase, non...	Mouse	Baculovirus Insect Cells
	PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of PTPN6 with its substrates. PTPN6 is expressed primarily in hematopoietic cells, and functions as an ...
TMPJ-00128	SLAMF2 Protein, Mouse, Recombinant (His) BCM1,SLAMF2,CD48,BLAST1,SLAM Family Member 2	Mouse	HEK293 Cells
	CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells (DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. C...
TMPK-00125	FLT3 Ligand Protein, Human, Recombinant (hFc) FLT3LG,FL,Flt3 ligand,SL cytokine,Flt3L	Human	HEK293 Cells
	Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Ligand Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.8 kDa and the accession number is P49771-1.
TMPY-01299	GMF gamma/GMFG Protein, Human, Recombinant (His) glia maturation factor, γ,glia maturation factor, gamma,GMF-...	Human	E. coli
	The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG expression independently predicts poorer prognosis in patients with EOC. Ectopic overexpression of GMFG contributes to the malignant biological behavior of ovarian cancer cells.
TMPJ-00005	CCL3 Protein, Human, Recombinant MIP-1-Alpha,CCL3,MIP-1-α,Small-Inducible Cytokine A3,C-C Mot...	Human	E. coli
	Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3.
TMPJ-00708	CST7 Protein, Mouse, Recombinant (His) CMAP,Cystatin-7,Leukocystatin,Cystatin-like Metastasis-Assoc...	Mouse	HEK293 Cells
	Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a biomarker for both liver metastasis and inflammatory lung disorders. Mouse Cystatin F inhibits papain and cathepsin L but with affinities lower than other cystatins. It may play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
TMPK-01054	CD2 Protein, Cynomolgus, Recombinant (aa 25-209, His) SRBC,T11,LFA-3 receptor,LFA-2,CD2	Cynomolgus	HEK293 Cells
	The CD2 family of receptors is evolutionarily conserved and widely expressed on cells within the hematopoietic compartment. In recent years several new members have been identified with important roles in the immune system. CD2 family members regulate natural killer (NK) cell lytic activity and inflammatory cytokine production when engaged by ligands on tumor cells.
TMPH-00281	IL-7 Protein, Bovine, Recombinant (His) IL7,Interleukin-7	Bovine	E. coli
	Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL-7 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P26895.
TMPK-00356	IL-27RA/TCCR Protein, Human, Recombinant (His) WSX1,IL-27 RA,IL27R α,CRL1,IL27RA,IL27R alpha,IL-27R-alpha,W...	Human	HEK293 Cells
	IL-27Ra (also known as TCCR and WSX1) as a gene whose expression can induce the transformation of hematopoietic cells. IL-27Ra (IL-27R) is a type I cytokine receptor that functions as the ligand binding component of the receptor for IL-27 and functions with the glycoprotein 130 (gp130) coreceptor to induce signal transduction in response to IL-27.
TMPJ-00831	CCL3 Protein, Mouse, Recombinant (His) LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha,LD78 alpha,chemokine (C-C ...	Mouse	E. coli
	C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra...
TMPJ-00006	CXCL1 Protein, Mouse, Recombinant (His) Scyb1,Growth-regulated α,Mgsa,Gro1,Growth-regulated alpha pr...	Mouse	HEK293 Cells
	Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical ...
TMPK-00655	IL-3 Protein, Cynomolgus, Recombinant (His) MCGF,IL3,MULTI-CSF,IL-3MGC79398,interleukin-3,IL-3	Cynomolgus	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 15.13 kDa and the acce...
TMPK-00032	IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated 白细胞介素,白介素,interleukin-3,MULTI-CSF,IL-3,IL3,IL-3MGC79398,MCGF	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 16....
TMPY-02379	EED Protein, Human, Recombinant (His & GST) HEED,WAIT1,embryonic ectoderm development	Human	Baculovirus Insect Cells
	EED is essential for regulating the repressive histone modification, histone 3 lysine 27 tri-methylation (H3K27me3) at many developmental genes. EED depletion significantly impeded erythroid maturation. EED depletion impaired the generation of hematopoietic stem cells. The function of EED within polycomb repressive complex 2 (PRC2) is mediated by a complex network of protein-protein interactions. The targeted disruption of EED's reader function can lead to allosteric inhibition of PRC2 catalyti...
TMPK-00562	CD31/PECAM-1 Protein, Cynomolgus, Recombinant (His) FLJ58394,PECAM-1,GPIIA',FLJ34100,EndoCAM,PECA1,CD31	Cynomolgus	HEK293 Cells
	Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular responsiveness. CD31/PECAM-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 65.30 kDa and the accession number is A0A7N9CHZ3.
TMPK-00695	N Cadherin Protein, Human, Recombinant (hFc) CDHN,Neural cadherin,CDH2,N-cadherin,CDw325,CD325,NCAD	Human	HEK293 Cells
	Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment.
TMPK-01042	FcRH6/FCRL6 Protein, Human, Recombinant (His) Fc receptor homolog 6,IFGP6,FcR-like protein 6,FLJ16056,Fc r...	Human	HEK293 Cells
	Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed that FCRL6 expression by NK- and T-cell subpopulations increases as a function of differentiation and is remarkably restricted to mature lymphocytes with cytotoxic capability.
TMPK-00834	CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His) PECAM-1,FLJ58394,GPIIA',PECA1,EndoCAM,FLJ34100,CD31	Human	HEK293 Cells
	Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular responsiveness. CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 65.6 kDa and the accession number is P16284-1.
TMPK-00833	CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, hFc) FLJ34100,EndoCAM,PECA1,PECAM-1,FLJ58394,GPIIA',CD31	Human	HEK293 Cells
	Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular responsiveness. CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 91.2 kDa and the accession number is P16284-1.
TMPK-00590	IL-3 Protein, Human, Recombinant (E. coli) interleukin-3,IL-3,MULTI-CSF,MCGF,IL-3MGC79398,IL3	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant（E. coli） is expressed in E. coli expression system. The predicted molecular weight is 15.09 kDa and the accession number is A...
TMPJ-00879	HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His) Homeobox protein Hox-2.6,HOX2F,HOXB4,Homeobox protein Hox-2F...	Human	E. coli
	Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation ...
TMPJ-00123	FLT3LG Protein, Mouse, Recombinant (His) Fms-related tyrosine kinase 3 ligand (Flt3L),Flt3 ligand,SL ...	Mouse	HEK293 Cells
	Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and colony stimulating factor. Flt3L synergizes well with a number of other colony stimulating factors and interleukins. Flt3L stimulates the proliferation and differentiation of various blood cell progentiors by activating FLT3.
TMPY-04380	DYRK3 Protein, Human, Recombinant (His & GST) REDK,RED,DYRK5,dual-specificity tyrosine-(Y)-phosphorylation...	Human	Baculovirus Insect Cells
	Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase family and MNB/DYRK subfamily. DYRKs are an emerging family of dual-specificity kinases that play key roles in cell proliferation, survival, and development. DYRK3 contains oneprotein kinase domain. Isoform 1 and isoform 2 of DYRK3 are highly expressed in testis and in hemat...
TMPK-00323	M-CSF/CSF1 Protein, Human, Recombinant (His & Avi) CSF-1,Lanimostim,M-CSF,MCSF,MGC31930,CSF1,集落刺激因子	Human	HEK293 Cells
	CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. M-CSF/CSF1 Protein, Human, Recombinant (...
TMPY-02795	Eotaxin-2 Protein, Human, Recombinant (His) MPIF-2,chemokine (C-C motif) ligand 24,SCYA24,MPIF2,Ckb-6	Human	Baculovirus Insect Cells
	CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is als...
TMPK-00049	IL-3 Protein, Mouse, Recombinant (hFc) IL3,MULTI-CSF,MCGF,白细胞介素,IL-3MGC79398,IL-3,白介素,interleukin-3	Mouse	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.2 kDa and the accession num...
TMPK-00033	IL-3 Protein, Human, Recombinant (hFc) IL3,interleukin-3,IL-3,MULTI-CSF,白介素,白细胞介素,IL-3MGC79398,MCGF	Human	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 41.6 kDa and the accession num...
TMPK-00031	IL-3 Protein, Human, Recombinant (His & Avi) IL-3,IL3,IL-3MGC79398,白介素,interleukin-3,MULTI-CSF,白细胞介素,MCGF	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 16.9 kDa and the ...
TMPH-01973	Proteoglycan 4 Protein, Human, Recombinant (His) PRG4,Megakaryocyte-stimulating factor,Superficial zone prote...	Human	P. pastoris (Yeast)
	Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.; Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages. Proteoglycan 4 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 1...
TMPY-04391	Lyn Protein, Human, Recombinant (GST) JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p...	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif...
TMPY-00975	FSTL3 Protein, Mouse, Recombinant (His) E030038F23Rik,Flrg,follistatin-like 3 (secreted glycoprotein...	Mouse	HEK293 Cells
	Follistatin-like 3 (FLRG/Fstl3) is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. FLRG/Fstl3 is a recently described member of the FST family having an overall structure and activity profile similar to that of FST, including binding and neutralization of activin. FLRG/Fstl3 is expressed in a wide range of adult tissues, not detected in hematopoietic cells except in patients with a B cell chronic leukemia and a translocation. Isoform 1 or t...
TMPK-00237	2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated NAIL,CD244,SLAMF4,h2B4,NKR2B4,Nmrk,CD244 antigen,2B4	Human	HEK293 Cells
	2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness.
TMPY-00518	SBDS Protein, Human, Recombinant (His) CGI-97,Shwachman-Bodian-Diamond syndrome,SDS,SWDS	Human	E. coli
	The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disorders, including hematopoietic dysfunction. SBDS deficiency leads to telomere shortening, that SBDS is a telomere-protecting protein that participates in regulating telomerase recruitment. SBDS Protein, Human, Recombinant (His) is expressed in E. coli expression system with His ta...
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重组蛋白

SCF Protein, Mouse, Recombinant

Cat.No: TMPJ-00166

Species: Mouse

Expression System: E. coli

IL-3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00051

Species: Mouse

Expression System: HEK293 Cells

HCLS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00515

Species: Human

Expression System: HEK293 Cells

DAP10 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03977

Species: Human

Expression System: HEK293 Cells

Carboxypeptidase Q Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01393

Species: Mouse

Expression System: HEK293 Cells

HPGDS/PGD2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04077

Species: Human

Expression System: E. coli

SCF Protein, Rat, Recombinant (His)

Cat.No: TMPJ-00894

Species: Rat

Expression System: E. coli

PTP1C Protein, Human, Recombinant (His)

Cat.No: TMPJ-00465

Species: Human

Expression System: E. coli

PGDS Protein, Human, Recombinant

Cat.No: TMPJ-00690

Species: Human

Expression System: E. coli

SCF Protein, Human, Recombinant

Cat.No: TMPJ-01470

Species: Human

Expression System: E. coli

M-CSF/CSF1 Protein, Rat, Recombinant

Cat.No: TMPJ-01218

Species: Rat

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-01465

Species: Human

Expression System: E. coli

EPO/Erythropoietin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00071

Species: Human

Expression System: HEK293 Cells

FOLR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01280

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00412

Species: Human

Expression System: HEK293 Cells

YJEFN3 Protein, Human, Recombinant

Cat.No: TMPH-02316

Species: Human

Expression System: E. coli

FLT3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00929

Species: Mouse

Expression System: HEK293 Cells

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)

Cat.No: TMPY-03296

Species: Mouse

Expression System: Baculovirus Insect Cells

SLAMF2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00128

Species: Mouse

Expression System: HEK293 Cells

FLT3 Ligand Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00125

Species: Human

Expression System: HEK293 Cells

GMF gamma/GMFG Protein, Human, Recombinant (His)

Cat.No: TMPY-01299

Species: Human

Expression System: E. coli

CCL3 Protein, Human, Recombinant

Cat.No: TMPJ-00005

Species: Human

Expression System: E. coli

CST7 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00708

Species: Mouse

Expression System: HEK293 Cells

CD2 Protein, Cynomolgus, Recombinant (aa 25-209, His)

Cat.No: TMPK-01054

Species: Cynomolgus

Expression System: HEK293 Cells

IL-7 Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00281

Species: Bovine

Expression System: E. coli

IL-27RA/TCCR Protein, Human, Recombinant (His)

Cat.No: TMPK-00356

Species: Human

Expression System: HEK293 Cells

CCL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00831

Species: Mouse

Expression System: E. coli

CXCL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00006

Species: Mouse

Expression System: HEK293 Cells

IL-3 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00655

Species: Cynomolgus

Expression System: E. coli

IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00032

Species: Human

Expression System: E. coli

EED Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02379

Species: Human

Expression System: Baculovirus Insect Cells

CD31/PECAM-1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00562

Species: Cynomolgus

Expression System: HEK293 Cells

N Cadherin Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00695

Species: Human

Expression System: HEK293 Cells

FcRH6/FCRL6 Protein, Human, Recombinant (His)

Cat.No: TMPK-01042

Species: Human

Expression System: HEK293 Cells

CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His)

Cat.No: TMPK-00834

Species: Human

Expression System: HEK293 Cells

CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, hFc)

Cat.No: TMPK-00833

Species: Human

Expression System: HEK293 Cells

IL-3 Protein, Human, Recombinant (E. coli)

Cat.No: TMPK-00590

Species: Human

Expression System: E. coli

HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)

Cat.No: TMPJ-00879

Species: Human

Expression System: E. coli

FLT3LG Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00123

Species: Mouse

Expression System: HEK293 Cells

DYRK3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04380

Species: Human

Expression System: Baculovirus Insect Cells

M-CSF/CSF1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00323

Species: Human

Expression System: HEK293 Cells

Eotaxin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02795

Species: Human

Expression System: Baculovirus Insect Cells

IL-3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00049

Species: Mouse

Expression System: HEK293 Cells

IL-3 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00033

Species: Human

Expression System: HEK293 Cells

IL-3 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00031

Species: Human

Expression System: E. coli

Proteoglycan 4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01973

Species: Human

Expression System: P. pastoris (Yeast)

Lyn Protein, Human, Recombinant (GST)

Cat.No: TMPY-04391

Species: Human

Expression System: Baculovirus Insect Cells

FSTL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00975

Species: Mouse

Expression System: HEK293 Cells

2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated

Cat.No: TMPK-00237

Species: Human

Expression System: HEK293 Cells

SBDS Protein, Human, Recombinant (His)

Cat.No: TMPY-00518

Species: Human

Expression System: E. coli

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