首页工具

登录

搜索结果

Search Results for " glutamine "

Targets Recommended: TRP/TRPV Channel

51

抑制剂 & 化合物

14

天然产物

1

化合物库

15

重组蛋白

1

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；

化合物库

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

Cat. No.	Product Name	Target	Signaling Pathways
T36064	N-Oleoyl Glutamine Oleoyl-L-glutamine	TRP/TRPV Channel	Membrane transporter/Ion channel
	N-Oleoyl Glutamine (Oleoyl-L-glutamine) 是参与 PM20D1 调控的N-酰基氨基酸，拮抗瞬时受体电位（TRP）钙通道的 TRPV1。
T8171	Glycyl-glutamine Glycyl-L-glutamine monohydrate,甘氨酰-L-谷氨酰胺一水合物,Glycyl-L-glutamine,Glycylglutamine	Others	Others
	Glycyl-glutamine (Glycyl-L-glutamine monohydrate) 是 β-内啡肽(1-31) 的内源拮抗剂，是β-endorphin 的酶裂解产品。它是一种比谷氨酰胺 (Gln) 稳定的活性神经肽。
T5593	L-Alanyl-L-glutamine L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln	Others; Endogenous Metabolite	Metabolism; Others
	L-Alanyl-L-glutamine (Ala-Gln) 是一种由丙氨酸和谷氨酰胺组成的二肽，对抗氧化系统有益，能够减轻炎症，并能够在分解代谢情况下调节热休克蛋白 (HSP) 的反应。
T31944	Glutamine monofluorophosphate L-Glutamine monofluorophosphate,G-MFP	Others	Others
	Glutamine monofluorophosphate is used during the fluorotherapy of osteoporosis.
T64330	Nalpha-Fmoc-L-Glutamine Fmoc-Gln-OH,Fmoc-L-glutamine	Amino Acids and Derivatives	Metabolism
	Nalpha-Fmoc-L-Glutamine (Fmoc-Gln-OH) 是一种谷氨酰胺衍生物。
T40668	N-Palmitoyl-L-glutamine	Others	Others
	N-Palmitoyl-L-glutamine is a Glutamine derivative.
T31965	Glycotriosyl glutamine Triglc-gln	Others	Others
	Glycotriosyl glutamine is a nephritogenoside analog.
T34678	Sodium phenylacetyl glutamine Antineoplaston AS 2-5	Others	Others
	Sodium phenylacetyl glutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a common metabolite that is naturally occurring in human urine.
T76574	Arginyl-Glutamine
	Arginyl-Glutamine 是一种二肽，可以降低VEGF 水平，并抑制氧诱导视网膜病变小鼠模型中的视网膜新生血管。
T67539	N-Carbobenzyloxy-L-glutamine	Others	Others
	N-Carbobenzyloxy-L-glutamine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67539。
T25454	Glutamamide L-Glutamine amide,Pentanediamide, 2-amino-, (2S)-	Others	Others
	Glutamamide is an anticancer drug.
T124414	N-(1-Carboxy-2-phenylethyl)glutamine	Others	Others
	N-(1-Carboxy-2-phenylethyl)glutamine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124414，CAS号为 6810-81-7。
T15411	GPNA hydrochloride	Apoptosis; Others	Apoptosis; Others
	GPNA hydrochloride 是一种 γ-谷氨酰转移酶的知名底物，可逆地诱导 A549 细胞凋亡。它是一种特定的谷氨酰胺转运蛋白ASCT2抑制剂，还抑制依赖 Na+的载体，如 SNAT 家族 (SNAT1/2/4/5) 和不依赖 Na+的亮氨酸转运蛋白 LAT1/2。
T32733	L-Glutamic acid, N-nicotinoyl-, disodium salt L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt,N-(3-Pyridinylcarbonyl)glutamine disodium salt	Others	Others
	L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt is a bioactive chemical.
T5345	V-9302	Others	Others
	V-9302 是一种跨膜谷氨酰胺通量的竞争性拮抗剂。它选择性的靶向氨基酸转运体 ASCT2 (SLC1A5)，不影响 ASCT1。它能够阻碍 HEK-293 细胞中由 ASCT2 介导的谷氨酰胺摄取 (IC50=9.6 μM)。
T31824	Fluoroglutamine (2S,4R) FDG	Others	Others
	Fluoroglutamine (2S,4R) is a Glutamine analog, not metabolized in the TCA cycle, but it can be incorporated into proteins and peptides. Fluoroglutamine (2S,4R) can be used as assess transporter (ASCT2) activity or protein synthesis rate.
T33355	Methylseleno carboxyethylglutamine Peptiselene	Others	Others
	Methylseleno carboxyethylglutamine is a bioactive chemical.
T33609	N-Butoxyacetylglutamine Baa-gln	Others	Others
	N-Butoxyacetylglutamine is a metabolite of N-butoxyacetic acid.
T33572	N-Acetylglutaminylglutamine amide NAGGN	Others	Others
	N-Acetylglutaminylglutamine amide, as an unusual dipeptide, can be accumulated during osmotic stress in Rhizobium meliloti.
T34207	Pyroglutamylglutamine diketopiperazine Pglu-glu dkm	Others	Others
	Pyroglutamylglutamine diketopiperazine is a bioactive chemical.
T62560	Sirpiglenastat DRP-104	Glutaminase	Proteases/Proteasome
	Sirpiglenastat (DRP-104) 是一种谷氨酰胺 (glutamine) 拮抗剂，是DON的前药，具有抗肿瘤活性，通过抑制谷氨酰胺代谢和刺激先天性和适应性免疫系统来发挥作用。
T9085	JFD01307SC [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]	Antibacterial	Microbiology/Virology
	JFD01307SC ([(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]) 是一种谷氨酰胺合成酶抑制剂。它是抗结核剂，可作为 L-谷氨酸盐的模拟物，靶向参与谷氨酰胺生物合成的酶。
T41299	L-Methionine-DL-sulfoximine MSX,MSO	Others	Others
	L-Methionine-DL-sulfoximine (MSO) 抑制谷氨酰胺合成酶，主要在代谢和形态上影响星形胶质细胞。L-Methionine-DL-sulfoximine 可用于惊厥相关研究。
T67865	BJJF078	Glutaminase	Proteases/Proteasome
	BJJF078 是一种氨基哌啶衍生物，是一种有效的重组人和小鼠谷氨酰胺转氨酶 (TG2) 活性的抑制剂，对人和小鼠谷氨酰胺转氨酶的IC50 值分别为 41 和 54 nM。BJJF078 对 TG1 酶有抑制作用，其IC50 为 0.16 μM。 BJJF078 可用于研究多发性硬化症 (MS) 。
T9372	D-Histidine	Mitochondrial Metabolism	Metabolism
	D-Histidine 是一种 L-histidine 的对映体。其中 L-histidine 是婴儿必需的氨基酸，是一种线粒体谷氨酰胺转运的抑制剂。
T11717	JHU395	Apoptosis	Apoptosis
	JHU395 是一种口服生物利用度高的前药，其活性成分是亲脂性谷氨酸拮抗剂（GA，6-叠氮-5-酮-L-去亚硝基赖氨酸）。JHU395 能有效地将DON输送至恶性周围神经鞘瘤（MPNST）的体外和体内模型中，并在MPNST上显现出显著的抗肿瘤活性。此外，JHU395在血浆中表现出良好的稳定性。
T78362	Transglutaminase TG
	Transglutaminase (TG) 是一种硫醇酶，促使蛋白质分子间交联，通过催化谷氨酰胺残基的γ-羧酰胺基团与其他化合物的一级ε-胺基团形成异肽键。该酶在包括凝血、抗菌免疫反应和光合作用在内的多种生理过程中发挥作用。
TP1616L	Hsp70-derived octapeptide acetate Hsp70-derived octapeptide acetate(736171-62-3 free base)	Others	Others
	Hsp70-derived octapeptide acetate (Hsp70-derived octapeptide acetate)(736171-62-3 free base) 是一组含有四肽重复 (TPR) 的蛋白质，已显示与 70 kDa 热休克同源蛋白 (hsc70) 的 C 末端结构域相互作用。在本研究中，含 TPR 的蛋白质，包括 hsc70 相互作用蛋白 (CHIP)、TPR1 和人富含谷氨酰胺的 TPR 含蛋白 (hSGT) 的 C 端，对 DnaJ 和 hsc70 对荧光素酶重折叠的影响进行了调查。
T27217	Duazomycin Duazomycin A,Acetyl-don,Diazomycin A,NSC 51097	Others	Others
	Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.
T70016	Methionine sulfoximine	Others	Others
	Methionine sulfoximine (MSO) is an irreversible glutamine synthetase inhibitor. It is the sulfoximine derivative of methionine with convulsant effects.
T40064	V-9302 hydrochloride	Others	Others
	V-9302 hydrochloride is a potent and selective competitive antagonist that inhibits transmembrane glutamine flux by specifically targeting the amino acid transporter ASCT2 (SLC1A5), and not ASCT1. In HEK-293 cells, V-9302 hydrochloride effectively inhibits ASCT2-mediated glutamine uptake with an IC50 value of 9.6 μM.
T26729	Azotomycin Antibiotic 1719,NSC 56654,Duazomycin B	Others	Others
	Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.
T69068	Aspulvinone H	Others	Others
	Aspulvinone H is a natural inhibitor of glutamic oxaloacetate transaminase 1 (GOT1), suppressing glutamine metabolism, making PDAC cells sensitive to oxidative stress and inhibiting cell proliferation, exhibiting potent in vivo antitumor activity in an SW1990-cell-induced xenograft model.
TP1420	Microtubule-associated protein tau (26-44)
	Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
TP1460	NH2-KLGADTDGEQDQHMTYGGQ-COOH
	NH2-QGGYTMHQDQEGDTDAGLK-COOH is a synthetic peptide chain consisting of a primary amine group attached to lysine and a carboxyl group attached to glutamine.
T78892	Glutaminase C-IN-2	Glutaminase	Proteases/Proteasome
	GlutaminaseC-IN-2（compound 11）为GAC变构抑制剂，IC50值为10.64 nM。该化合物通过干扰谷氨酰胺代谢，调控细胞代谢产物，进而提高ROS水平，并展现出抗癌活性。
T37222	GLS1 Inhibitor	Others	Others
	GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50= 0.021 μM).1It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cellsin vitro(GI50= 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model. 1.Finlay, M.R.V., Anderton, M., Bailey, A., et al.Discovery of a thiadiazole-pyridazine-based allosteric glutaminase 1 inhibitor series that demons...
T73885	Methyl gerfelin	Others	Others
	Methyl gerfelin通过与三种关键细胞蛋白乙二醛酶 1 (GLO1)、固醇结合蛋白 2 (SCP2) 和富含谷氨酰胺的四肽重复蛋白 A (SGTA) 结合，抑制破骨细胞的分化。研究表明，Methyl gerfelin是一种与类黄酮相关的强效GLO1抑制剂。
T80566	Temtokibart
	Temtokibart为一种IgG1λ2抗体，靶向IL22RA1并进行人源化处理，由剔除谷氨酰胺合成酶基因的细胞所表达。
T69056	Albizziin	Others	Others
	Albizziin is amino acid analog which acts as a competitive inhibitor of asparagine synthetase with respect to glutamine. Albizziin has been used to isolate mutants of Chinese hamster ovary cells with alterations in levels of the target enzyme. Several classes of mutations can be distinguished on the basis of cross-resistance to beta-aspartyl hydroxamate, another amino acid analog. Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagin...
T73458	LWG-301	Others	Others
	LWG-301是一种针对Glutaminase1(GLS1)的变构抑制剂，具有(IC50=7 nM)。通过显著阻断谷氨酰胺代谢并增加细胞内ROS，LWG-301能够诱导细胞凋亡(apoptosis)。在HCT116异种移植模型中，LWG-301展示出中等抗肿瘤活性。
T80559	Duvakitug
	Duvakitug为针对TNFSF15/TL1A的人源IgG1-λ2型单克隆抗体，在CHOK1SV细胞系的内源性谷氨酰胺合成酶(GS)阳性细胞中表达，适用于克罗恩病（Crohn's Disease, CD）研究。
T77991	Glutaurine TFA Litoralon TFA
	Glutaurine (Litoralon) TFA，含谷氨酰胺与牛磺酸残基，为甲状旁腺源嗜氧细胞分离的口服活性激素。该化合物在抗癫痫与抗健忘症研究中有应用。
T25455L	Glutaurine aceate	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	含有谷氨酰胺和牛磺酸残基的 Glutaurine aceate 是甲状旁腺的一种口服活性激素。Glutaurine 作为一种激素，从甲状旁腺嗜氧细胞中分离出来。Glutaurine 可用于抗癫痫和抗遗忘的研究。
TP1616	Hsp70-derived octapeptide
	A group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing proteins, including the C-terminus
T72679	GLS1 Inhibitor-4	Glutaminase	Proteases/Proteasome
	GLS1 Inhibitor-4 (compound 41e)作为一种高效的GLS1抑制剂，具有11.86 nM的IC50值。该化合物展现了抗增殖效果、优秀的代谢稳定性以及强大的GLS1结合亲和力。它通过阻断谷氨酰胺代谢和诱导ROS生成，能够引发细胞凋亡并表现出对抗肿瘤的活性。
T80249	Epsilon-V1-2, Cys-conjugated	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Epsilon-V1-2, Cys-conjugated 是 εPKC 特异性抑制剂，通过阻断 εPKC 与 εRACK 锚定蛋白之间的相互作用，抑制 εPKC 易位及 MARCKS 磷酸化，从而表现生物活性。该肽将半胱氨酸残基接到 C 末端，以形成与载体蛋白的 SS 键。当序列 N 末端为谷氨酰胺 (Q) 或谷氨酸 (E) 时，肽可自发生成焦谷氨酰 (pGlu)。Q或E到pGlu的转化属于自然过程，并且pGlu的疏水性γ-内酰胺环对提高肽对胃肠道蛋白酶的稳定性起关键作用。在 HPLC 分析中，焦谷氨酰肽作为肽纯度的一部分进行检测，视为这类肽的典型子集。
T82504	EE epitope
	EE epitope 是一种具有生物活性的肽，源自小鼠多瘤病毒中间 T 抗原的氨基酸片段（314 至 319）。以 Glu-Glu 为特征的表位肽被广泛用作表位标签。当序列的 N 末端含有谷氨酰胺 (Q) 或谷氨酸 (E) 时，可能会自发形成焦谷氨酰 (pGlu) 肽。Q 或 E 至 pGlu 的转换是自然过程，所形成的疏水性 γ-内酰胺环被认为有助于提高针对胃肠道蛋白酶的肽稳定性。因此，在 HPLC 分析中，这些焦谷氨酰肽作为正常的肽子集纳入考量，用于评估肽的纯度。
T81825	Melan-A/MART-1 analog [Leu27]-Melan-A, MART-1 (26-35)
	[Leu27]-Melan-A, MART-1 (26-35)是一种具有改良的HLA-A*0201结合能力和增强的免疫原性及抗原性的生物活性肽。该类似物在第27位的Leu替换了Ala，与原生Melan-A (26-35)相比表现出更佳的性能。当序列N端为谷氨酰胺(Q)或谷氨酸(E)时，肽可能会自发形成焦谷氨酰(pGlu)。Q或E到pGlu的转化是自然发生的，pGlu的疏水性γ-内酰胺环被认为可增强针对胃肠道蛋白酶的抵抗力，使得含pGlu的肽成为这类肽的正常子集，在HPLC分析中通常作为评估肽纯度的一部分。
T82071	Influenza NP (311-325)
	Influenza NP (311-325) 是具有生物活性的肽段，对应于流感病毒核蛋白(NP)的311至325氨基酸。作为MHC II类限制性表位，它用于研究宿主在感染期间的免疫响应。该肽能在细胞内细胞因子检测中诱导强烈的γ干扰素(IFN-γ)产生，但不激活小鼠CD8 T细胞。谷氨酰胺(Q)或谷氨酸(E)位于N端时，焦谷氨酰(pGlu)肽可自发形成。Q或E向pGlu的自然转化及其疏水性γ-内酰胺环在肽的胃肠道蛋白酶稳定性中可能起作用。焦谷氨酰肽作为常见肽的一部分，在HPLC分析中评估肽的纯度。

化合物

N-Oleoyl Glutamine

Cat.No: T36064

Synonym: Oleoyl-L-glutamine

Target: TRP/TRPV Channel

Glycyl-glutamine

Cat.No: T8171

Synonym: Glycyl-L-glutamine monohydrate,甘氨酰-L-谷氨酰胺一水合物,Glycyl-L-glutamine,Glycylglutamine

Target: Others

L-Alanyl-L-glutamine

Cat.No: T5593

Synonym: L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln

Target: Others, Endogenous Metabolite

Glutamine monofluorophosphate

Cat.No: T31944

Synonym: L-Glutamine monofluorophosphate,G-MFP

Target: Others

Nalpha-Fmoc-L-Glutamine

Cat.No: T64330

Synonym: Fmoc-Gln-OH,Fmoc-L-glutamine

Target: Amino Acids and Derivatives

N-Palmitoyl-L-glutamine

Cat.No: T40668

Target: Others

Glycotriosyl glutamine

Cat.No: T31965

Synonym: Triglc-gln

Target: Others

Sodium phenylacetyl glutamine

Cat.No: T34678

Synonym: Antineoplaston AS 2-5

Target: Others

Arginyl-Glutamine

Cat.No: T76574

N-Carbobenzyloxy-L-glutamine

Cat.No: T67539

Target: Others

Cat.No: T25454

Synonym: L-Glutamine amide,Pentanediamide, 2-amino-, (2S)-

Target: Others

N-(1-Carboxy-2-phenylethyl)glutamine

Cat.No: T124414

Target: Others

GPNA hydrochloride

Cat.No: T15411

Target: Apoptosis, Others

L-Glutamic acid, N-nicotinoyl-, disodium salt

Cat.No: T32733

Synonym: L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt,N-(3-Pyridinylcarbonyl)glutamine disodium salt

Target: Others

Cat.No: T5345

Target: Others

Fluoroglutamine (2S,4R)

Cat.No: T31824

Synonym: FDG

Target: Others

Methylseleno carboxyethylglutamine

Cat.No: T33355

Synonym: Peptiselene

Target: Others

N-Butoxyacetylglutamine

Cat.No: T33609

Synonym: Baa-gln

Target: Others

N-Acetylglutaminylglutamine amide

Cat.No: T33572

Synonym: NAGGN

Target: Others

Pyroglutamylglutamine diketopiperazine

Cat.No: T34207

Synonym: Pglu-glu dkm

Target: Others

Cat.No: T62560

Synonym: DRP-104

Target: Glutaminase

Cat.No: T9085

Synonym: [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]

Target: Antibacterial

L-Methionine-DL-sulfoximine

Cat.No: T41299

Synonym: MSX,MSO

Target: Others

Cat.No: T67865

Target: Glutaminase

Cat.No: T9372

Target: Mitochondrial Metabolism

Cat.No: T11717

Target: Apoptosis

Transglutaminase

Cat.No: T78362

Synonym: TG

Hsp70-derived octapeptide acetate

Cat.No: TP1616L

Synonym: Hsp70-derived octapeptide acetate(736171-62-3 free base)

Target: Others

Cat.No: T27217

Synonym: Duazomycin A,Acetyl-don,Diazomycin A,NSC 51097

Target: Others

Methionine sulfoximine

Cat.No: T70016

Target: Others

V-9302 hydrochloride

Cat.No: T40064

Target: Others

Cat.No: T26729

Synonym: Antibiotic 1719,NSC 56654,Duazomycin B

Target: Others

Cat.No: T69068

Target: Others

Microtubule-associated protein tau (26-44)

Cat.No: TP1420

NH2-KLGADTDGEQDQHMTYGGQ-COOH

Cat.No: TP1460

Glutaminase C-IN-2

Cat.No: T78892

Target: Glutaminase

Cat.No: T37222

Target: Others

Methyl gerfelin

Cat.No: T73885

Target: Others

Cat.No: T80566

Cat.No: T69056

Target: Others

Cat.No: T73458

Target: Others

Cat.No: T80559

Cat.No: T77991

Synonym: Litoralon TFA

Glutaurine aceate

Cat.No: T25455L

Target: Thyroid hormone receptor(THR)

Hsp70-derived octapeptide

Cat.No: TP1616

GLS1 Inhibitor-4

Cat.No: T72679

Target: Glutaminase

Epsilon-V1-2, Cys-conjugated

Cat.No: T80249

Target: PKC

Cat.No: T82504

Melan-A/MART-1 analog

Cat.No: T81825

Synonym: [Leu27]-Melan-A, MART-1 (26-35)

Influenza NP (311-325)

Cat.No: T82071

Cat. No.	Product Name	Target	Signaling Pathways
T0326	DL-Glutamine Glutamin,DL-Gl,(±)-Glutamine,DL-谷氨酰胺,2-amino-4-carbamoylbutanoic acid	Ferroptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	DL-Glutamine (2-amino-4-carbamoylbutanoic acid) 是一种非必需氨基酸，大量存在于全身并参与许多代谢过程。它由谷氨酸和氨合成，是体内氮的主要载体，是许多细胞的重要能量来源，用于制药和供生物化学研究。
T6468	D-glutamine	Mitophagy; Ferroptosis; Endogenous Metabolite; GluR; Autophagy	Apoptosis; Autophagy; Metabolism; Neuroscience
	D-Glutamine 是有细胞渗透性谷氨酰胺的 D 型立体异构体，是标准遗传密码编码的20种氨基酸之一。
T0326L	L-Glutamine L-Glutamic acid 5-amide,L-谷氨酰胺	Ferroptosis; Endogenous Metabolite; GluR	Apoptosis; Metabolism; Neuroscience
	L-Glutamine (L-Glutamic acid 5-amide) 是在人体中大量存在的一种非必需氨基酸，由谷氨酸和氨合成。它为某些细胞中的氧化提供了碳源。
T0769	Aceglutamide N-乙酰-L-谷氨酰胺,N2-Acetylglutamine,α-N-Acetyl-L-glutamine,乙酰谷酰胺	Amino Acids and Derivatives; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Aceglutamide (N2-Acetylglutamine) 是一种精神激活剂和促智剂，是氨基酸 L-谷氨酰胺的乙酰衍生物，用于改善记忆和集中注意力。
T5265	Phenylacetylglutamine NSC 203800,N-苯乙酰基-L-谷氨酰胺,Phenyl-Ac-Gln-OH,Phenylacetyl-L-glutamine	Others; Endogenous Metabolite	Metabolism; Others
	Phenylacetylglutamine (NSC 203800) 是结肠微生物的代谢物，源于氨基酸发酵。
T0507	L-Pyroglutamic acid L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline	Others; Endogenous Metabolite	Metabolism; Others
	L-Pyroglutamic acid (pidolic acid) 是 Pyroglutamic acid 的左旋异构体，是人体中具有生物特性的对映异构体。Pyroglutamic acid 是谷胱甘肽代谢中的中间体。
T5980	2-Ketoglutaric acid α-酮戊二酸,alpha-酮戊二酸	Tyrosinase; Endogenous Metabolite	Metabolism; Proteases/Proteasome
	2-Ketoglutaric acid 是 Krebs 循环的中间体，可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。
TQ0158	Azaserine CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine	Others; Antibiotic	Microbiology/Virology; Others
	Azaserine (CI-337) 是一种从链霉菌属中分离出来的肿瘤抑制抗生素，可作为谷氨酰胺氨基转移酶的抑制剂。
T4813	L-Citrulline	Endogenous Metabolite	Metabolism
	L-Citrulline 是一种氨基酸，源自于精氨酸-瓜氨酸途径获得的 l-精氨酸，或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
T4826	L-Histidine monohydrochloride monohydrat	Others; Endogenous Metabolite	Metabolism; Others
	L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一，即蛋白质的组成部分。
T81794	Micromonosporamide A
	Micromonosporamide A exhibits glutamine-dependent antiproliferative activity. Micromonosporamide A体现了以谷氨酰胺为依赖的抗增殖活性。
T78485	D-Glucosamine 6-phosphate Glucosamine-6-phosphate	Endogenous Metabolite	Metabolism
	D-Glucosamine 6-phosphate为内源性代谢分子，谷氨酰胺果糖-6-磷酸氨基转移酶(GFAT)介导合成。该化合物常用于糖尿病研究领域。
T36179	Aspulvinone O	Others	Others
	Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu...

天然产物

Cat.No: T0326

Synonym: Glutamin,DL-Gl,(±)-Glutamine,DL-谷氨酰胺,2-amino-4-carbamoylbutanoic acid

Target: Ferroptosis, Amino Acids and Derivatives, Endogenous Metabolite

Cat.No: T6468

Target: Mitophagy, Ferroptosis, Endogenous Metabolite, GluR, Autophagy

Cat.No: T0326L

Synonym: L-Glutamic acid 5-amide,L-谷氨酰胺

Target: Ferroptosis, Endogenous Metabolite, GluR

Cat.No: T0769

Synonym: N-乙酰-L-谷氨酰胺,N2-Acetylglutamine,α-N-Acetyl-L-glutamine,乙酰谷酰胺

Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy

Phenylacetylglutamine

Cat.No: T5265

Synonym: NSC 203800,N-苯乙酰基-L-谷氨酰胺,Phenyl-Ac-Gln-OH,Phenylacetyl-L-glutamine

Target: Others, Endogenous Metabolite

L-Pyroglutamic acid

Cat.No: T0507

Synonym: L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline

Target: Others, Endogenous Metabolite

2-Ketoglutaric acid

Cat.No: T5980

Synonym: α-酮戊二酸,alpha-酮戊二酸

Target: Tyrosinase, Endogenous Metabolite

Cat.No: TQ0158

Synonym: CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine

Target: Others, Antibiotic

Cat.No: T4813

Target: Endogenous Metabolite

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

L-Histidine monohydrochloride monohydrat

Cat.No: T4826

Target: Others, Endogenous Metabolite

Micromonosporamide A

Cat.No: T81794

D-Glucosamine 6-phosphate

Cat.No: T78485

Synonym: Glucosamine-6-phosphate

Target: Endogenous Metabolite

Cat.No: T36179

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00438	GLUL Protein, Cricetulus griseus, Recombinant (His) Glutamine synthetase,GLUL,Glutamate--ammonia ligase...	Chinese hamster	E. coli
	GLUL Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli.
TMPJ-00855	GLUL Protein, Human, Recombinant (His) GLUL,GS,Glutamine Synthetase,Glutamate-Ammonia Liga...	Human	E. coli
	Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency.
TMPJ-00900	TGM2 Protein, Mouse, Recombinant (His) Transglutaminase C,Tgm2,Tissue transglutaminase,TGase-2,Prot...	Mouse	HEK293 Cells
	Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
TMPH-03000	ATase Protein, Mycobacterium tuberculosis, Recombinant (His) ATase,Glutamine phosphoribosylpyrophosphate amidotr...	Mycobacterium tuberculosis	E. coli
	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. ATase Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.5 kDa and the accession number is P9WHQ6.
TMPJ-00489	NTAQ1 Protein, Human, Recombinant (GST) Nt(Q)-amidase,C8orf32,NTAQ1,Protein NH2-terminal glutami...	Human	E. coli
	Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it do...
TMPH-01597	KYAT1 Protein, Human, Recombinant (His & SUMO) Kynurenine aminotransferase 1,KYAT1,Glutamine--phen...	Human	E. coli
	Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cl...
TMPY-01189	GFPT1 Protein, Human, Recombinant GFAT1,CMSTA1,GFAT,glutamine--fructose-6-phosphate t...	Human	E. coli
	Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re...
TMPJ-00535	F13A Protein, Human, Recombinant (His) F13A1,Coagulation Factor XIII A Chain,Transglutaminase A Cha...	Human	HEK293 Cells
	Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium io...
TMPJ-00679	SGTA Protein, Human, Recombinant (His) α-SGT,Alpha-SGT,SGT,Small Glutamine-Rich Tetratrico...	Human	E. coli
	Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV...
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-ALPHA-h	Human	Baculovirus Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which...
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) Coagulation factor 13,coagulation factor XIII, B polypeptide...	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en...
TMPH-01862	PFAS Protein, Human, Recombinant (His & Myc & SUMO) Phosphoribosylformylglycinamidine synthase,Formylglycinamide...	Human	E. coli
	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. PFAS Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 45.4 kDa and the accession number is O15067.
TMPJ-00871	BAR Protein, S. hygroscopicus, Recombinant bar,PPT N-acetyltransferase,Phosphinothricin-resistance prot...	Streptomyces hygroscopicus	E. coli
	Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant...
TMPJ-01372	Cornulin Protein, Human, Recombinant (His) Tumor-Related Protein,58 kDa Heat Shock Protein,PDRC1,C1orf1...	Human	E. coli
	Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and ...
TMPJ-01452	Notch 1 Protein, Mouse, Recombinant (aa 18-526, His) mT14,Neurogenic locus notch homolog protein 1,Motch A,Notch ...	Mouse	HEK293 Cells
	Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531 amino acid (aa) precursor that contains an 18 aa signal sequence, a 1707 aa extracellular domain (ECD) with 36 EGFlike repeats and three Lin12/notch repeats, a 21 aa transmembrane segment and a 785 aa cytoplasmic domain that contains six ankyrin repeats, a glutamine-rich domain ...

重组蛋白

GLUL Protein, Cricetulus griseus, Recombinant (His)

Cat.No: TMPH-00438

Species: Chinese hamster

Expression System: E. coli

GLUL Protein, Human, Recombinant (His)

Cat.No: TMPJ-00855

Species: Human

Expression System: E. coli

TGM2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00900

Species: Mouse

Expression System: HEK293 Cells

ATase Protein, Mycobacterium tuberculosis, Recombinant (His)

Cat.No: TMPH-03000

Species: Mycobacterium tuberculosis

Expression System: E. coli

NTAQ1 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00489

Species: Human

Expression System: E. coli

KYAT1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01597

Species: Human

Expression System: E. coli

GFPT1 Protein, Human, Recombinant

Cat.No: TMPY-01189

Species: Human

Expression System: E. coli

F13A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00535

Species: Human

Expression System: HEK293 Cells

SGTA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00679

Species: Human

Expression System: E. coli

Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01355

Species: Human

Expression System: Baculovirus Insect Cells

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

Cat.No: TMPY-02185

Species: Human

Expression System: HEK293 Cells

PFAS Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01862

Species: Human

Expression System: E. coli

BAR Protein, S. hygroscopicus, Recombinant

Cat.No: TMPJ-00871

Species: Streptomyces hygroscopicus

Expression System: E. coli

Cornulin Protein, Human, Recombinant (His)

Cat.No: TMPJ-01372

Species: Human

Expression System: E. coli

Notch 1 Protein, Mouse, Recombinant (aa 18-526, His)

Cat.No: TMPJ-01452

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T12447	Phenylacetylglutamine-D5 NSC 203800-D5,Phenylacetyl-L-glutamine-D5	Others	Others
	Phenylacetylglutamine-D5 is a deuterated form of Phenylacetylglutamine.

同位素标记化合物

Phenylacetylglutamine-D5

Cat.No: T12447

Synonym: NSC 203800-D5,Phenylacetyl-L-glutamine-D5

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼