首页工具

登录

搜索结果

Search Results for " 5-htt "

Targets Recommended: Serotonin Transporter

24

抑制剂 & 化合物

3

天然产物

8

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T12232	Nitroxazepine CIBA 2330Go	Serotonin Transporter	Neuroscience
	Nitroxazepine (CIBA 2330Go) 是三环抗抑郁化合物，是一种 5-羟色胺去甲肾上腺素再摄取抑制剂，可用于抗抑郁的研究。
T8708	Paroxetine	Serotonin Transporter	Neuroscience
	Paroxetine 是选择性血清素再摄取抑制剂，是苯基哌啶的衍生物。它对于甲肾上腺素摄取抑制功能较弱，但比该位点其他SSRIs 更有效。
T22453	Venlafaxine Wy 45030,文拉法辛	Serotonin Transporter	Neuroscience
	Venlafaxine (Wy 45030) 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂，具有抗抑郁活性。
T0450	Fluoxetine 氟西汀,LY-110140	5-HT Receptor; Serotonin Transporter; MRP; Autophagy	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fluoxetine (LY-110140) 是一种高度特异性的血清素摄取抑制剂，是选择性 5-羟色胺 (5-HT) 再吸收抑制剂。Fluoxetine 具有抗抑郁活性。
T22714	Decynium 22	Others	Others
	Decynium 22 是有机阳离子转运蛋白和单胺转运蛋白的抑制剂，具有抗抑郁作用。
T1189	Milnacipran hydrochloride 盐酸米那普仑,Milnacipran HCl,Savella,Dalcipran	Serotonin Transporter; Norepinephrine	Neuroscience
	Milnacipran hydrochloride (Savella) 是一种5-羟色胺-去甲肾上腺素重吸收抑制剂（SNRI），可用于纤维肌痛的研究。
T2594	Dextromilnacipran Levomilnacipran,左旋米那普仑	Serotonin Transporter; Norepinephrine	Neuroscience
	Dextromilnacipran (Levomilnacipran) 是米那普仑的对映体，是一种选择性 5- 羟色胺和去甲肾上腺素(5-HT/NE)再摄取抑制剂，也是一种人类 α 肾上腺素能受体拮抗剂，IC50=3.4 μM。
T2395	Vortioxetine 沃替西汀,Lu AA 21004	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Vortioxetine (Lu AA 21004) 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂，Ki 值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药，用于治疗重度抑郁症。
T1279	Vilazodone 维拉佐酮,SB659746A,EMD 68843	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Vilazodone (SB659746A) 是一种可口服的选择性 5 -羟色胺再摄取抑制剂 (SSRI) 和部分5-HT1A 受体激动剂。它有抗抑郁作用，可用于抑郁症和情绪性疾病的研究。
T21013	Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina,氯米帕明	5-HT Receptor	GPCR/G Protein; Neuroscience
	Clomipramine (Clomicalm) 是一种三环类抗抑郁药，能够有效阻断 5-HT 再摄取 (IC50:1.5 nM) ，可用于研究强迫症 (OCD) 及抑郁症。
T0472	Venlafaxine hydrochloride Venlafaxine HCl,盐酸文拉法辛,Wy 45030 hydrochloride	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Venlafaxine hydrochloride (Wy 45030 hydrochloride) 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂，具有抗抑郁活性。
T6232	Vilazodone Hydrochloride 盐酸维拉佐酮,SB659746A,EMD 68843,Vilazodone HCl	Others; 5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience; Others
	Vilazodone Hydrochloride (EMD 68843) 是 5-HT1A 受体和特异性 5-羟色胺再摄取抑制剂(SSRI) 的部分激动剂，用于治疗重度抑郁症。
T1580	Desvenlafaxine 去甲文拉法辛,WY 45233 Succinate,O-Desmethylvenlafaxine	5-HT Receptor; Serotonin Transporter; Norepinephrine	GPCR/G Protein; Neuroscience
	Desvenlafaxine (O-Desmethylvenlafaxine) 是 Venlafaxine 主要代谢物的丁二酸盐形式，在人多巴胺转运体上显示弱的结合亲和力。它是一种具有口服活性的、能透过血脑屏障的5-HT 和去甲肾上腺素再摄取的抑制剂，对 hSERT 和 hNET 的IC50值分别为 47.3 nM 和 531.3 nM。
T0482	Sertraline hydrochloride Sertraline HCl,CP-51974-1 HCl,盐酸舍曲林	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Sertraline hydrochloride (Sertraline HCl) 是选择性 5- 羟色胺再吸收抑制剂类的抗抑郁剂，可用于多种疾病的研究，如重度抑郁症和强迫症。
T7940	Milnacipran ((1S-cis) hydrochloride) 左旋米那普林,Levomilnacipran Hydrochloride	Serotonin Transporter	Neuroscience
	Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) 是 5-羟色胺去甲肾上腺素再摄取抑制剂，用于研究纤维肌痛。
T0255	Clomipramine hydrochloride Clomipramine HCl,Anafranil,盐酸氯米帕明	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine; GST	GPCR/G Protein; Neuroscience; oxidation-reduction
	Clomipramine hydrochloride (Anafranil) 是一种5-羟色胺转运体(Ki:0.14 nM)、去甲肾上腺素转运体(Ki:54 nM)和多巴胺转运体(Ki:3 nM)阻断剂。
T7941	Imipramine hydrochloride 盐酸丙咪嗪,Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine	Serotonin Transporter	Neuroscience
	Imipramine hydrochloride (Imipramine HCl) 可抑制血清素转运蛋白，IC50=32 nM。它可阻止胰酶的易位，阻碍 MV 和外泌体的分泌。
T0678	Amitriptyline hydrochloride Amitriptyline HCl,Tryptizol,盐酸阿米替林,Domical,Annoyltin	Trk receptor; Sigma receptor; 5-HT Receptor; Serotonin Transporter; Sodium Channel; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors
	Amitriptyline hydrochloride (Annoyltin) 是血清素再摄取转运体和去甲肾上腺素再摄取转运体抑制剂，还与多巴胺再摄取转运体结合，其Ki 为 2.58 μM。它也抑制肾上腺素能受体、毒蕈碱受体、组胺受体、5-羟色胺受体。它是TrkA 和TrkA 受体的激动剂，具有强神经营养活性和有抗抑郁作用。
T6493	Escitalopram Oxalate 草酸右旋西酞普兰,依他普仑草酸盐,Cipralex,(S)-(+)Citalopram oxalate	Others; 5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience; Others
	Escitalopram Oxalate ((S)-(+)Citalopram oxalate) 是一种外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂，Ki=0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性，是一种研究抑郁症的抗抑郁药。
T2395L	Vortioxetine hydrobromide 氢溴酸沃替西汀,Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,盐酸沃替西汀,Lu AA21004 hydrobromide	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Vortioxetine hydrobromide (Lu AA21004 hydrobromide) 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和5-羟色胺转运体(SERT)的抑制剂，Ki 值分别为 15、33、3.7、19 和 1.6 nM。
T1077	Fluvoxamine maleate 氟伏沙明马来酸盐,马来酸氟伏沙明,MK-264,DU-23000 (maleate)	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Fluvoxamine maleate (DU-23000 (maleate)) 是一种5-羟色胺再吸收抑制剂，有抗抑郁作用。
T6188	Desvenlafaxine succinate hydrate O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,琥珀酸去甲文拉法辛,Desvenlafaxine Succinate	5-HT Receptor; Serotonin Transporter; Norepinephrine	GPCR/G Protein; Neuroscience
	Desvenlafaxine succinate hydrate (WY 45233 Succinate) 是 Venlafaxine 主要代谢物的丁二酸盐形式，在人多巴胺转运体上显示弱的结合亲和力。它是具有口服活性的、能透过血脑屏障的5-HT 和去甲肾上腺素再摄取的抑制剂，对 hSERT 和 hNET 的IC50值分别为47.3 nM 和531.3 nM。
T1483	Citalopram hydrobromide Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,氢溴酸西酞普兰,Citalopram HBr	5-HT Receptor; Serotonin Transporter; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Citalopram hydrobromide (XU-62-320) 是一种选择性 5-羟色胺再摄取抑制剂，可选择性地抑制 CNS 神经元对 5-羟色胺的再摄取，从而增强中枢神经系统中的 5-羟色胺能活性，也具有抗抑郁活性。它抑制兔血小板中 5-HT 的摄取，IC50为 14 nM。
T1471	Duloxetine hydrochloride Duloxetine HCl,盐酸度洛西汀,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine	GPCR/G Protein; Neuroscience
	Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI)，Ki=4.6 nM，可用于广泛性焦虑症的研究。

化合物

Cat.No: T12232

Synonym: CIBA 2330Go

Target: Serotonin Transporter

Cat.No: T8708

Target: Serotonin Transporter

Cat.No: T22453

Synonym: Wy 45030,文拉法辛

Target: Serotonin Transporter

Cat.No: T0450

Synonym: 氟西汀,LY-110140

Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy

Cat.No: T22714

Target: Others

Milnacipran hydrochloride

Cat.No: T1189

Synonym: 盐酸米那普仑,Milnacipran HCl,Savella,Dalcipran

Target: Serotonin Transporter, Norepinephrine

Dextromilnacipran

Cat.No: T2594

Synonym: Levomilnacipran,左旋米那普仑

Target: Serotonin Transporter, Norepinephrine

Cat.No: T2395

Synonym: 沃替西汀,Lu AA 21004

Target: 5-HT Receptor, Serotonin Transporter

Cat.No: T1279

Synonym: 维拉佐酮,SB659746A,EMD 68843

Target: 5-HT Receptor, Serotonin Transporter

Cat.No: T21013

Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina,氯米帕明

Target: 5-HT Receptor

Venlafaxine hydrochloride

Cat.No: T0472

Synonym: Venlafaxine HCl,盐酸文拉法辛,Wy 45030 hydrochloride

Target: 5-HT Receptor, Serotonin Transporter

Vilazodone Hydrochloride

Cat.No: T6232

Synonym: 盐酸维拉佐酮,SB659746A,EMD 68843,Vilazodone HCl

Target: Others, 5-HT Receptor, Serotonin Transporter

Cat.No: T1580

Synonym: 去甲文拉法辛,WY 45233 Succinate,O-Desmethylvenlafaxine

Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine

Sertraline hydrochloride

Cat.No: T0482

Synonym: Sertraline HCl,CP-51974-1 HCl,盐酸舍曲林

Target: 5-HT Receptor, Serotonin Transporter

Milnacipran ((1S-cis) hydrochloride)

Cat.No: T7940

Synonym: 左旋米那普林,Levomilnacipran Hydrochloride

Target: Serotonin Transporter

Clomipramine hydrochloride

Cat.No: T0255

Synonym: Clomipramine HCl,Anafranil,盐酸氯米帕明

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST

Imipramine hydrochloride

Cat.No: T7941

Synonym: 盐酸丙咪嗪,Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine

Target: Serotonin Transporter

Amitriptyline hydrochloride

Cat.No: T0678

Synonym: Amitriptyline HCl,Tryptizol,盐酸阿米替林,Domical,Annoyltin

Target: Trk receptor, Sigma receptor, 5-HT Receptor, Serotonin Transporter, Sodium Channel, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

Escitalopram Oxalate

Cat.No: T6493

Synonym: 草酸右旋西酞普兰,依他普仑草酸盐,Cipralex,(S)-(+)Citalopram oxalate

Target: Others, 5-HT Receptor, Serotonin Transporter

Vortioxetine hydrobromide

Cat.No: T2395L

Synonym: 氢溴酸沃替西汀,Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,盐酸沃替西汀,Lu AA21004 hydrobromide

Target: 5-HT Receptor, Serotonin Transporter

Fluvoxamine maleate

Cat.No: T1077

Synonym: 氟伏沙明马来酸盐,马来酸氟伏沙明,MK-264,DU-23000 (maleate)

Target: 5-HT Receptor, Serotonin Transporter

Desvenlafaxine succinate hydrate

Cat.No: T6188

Synonym: O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,琥珀酸去甲文拉法辛,Desvenlafaxine Succinate

Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine

Citalopram hydrobromide

Cat.No: T1483

Synonym: Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,氢溴酸西酞普兰,Citalopram HBr

Target: 5-HT Receptor, Serotonin Transporter, Autophagy

Duloxetine hydrochloride

Cat.No: T1471

Synonym: Duloxetine HCl,盐酸度洛西汀,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine

Cat. No.	Product Name	Target	Signaling Pathways
T7521	Azaphen Pipofezin hydrochloride,阿扎吩,Pipofezine hydrochloride,Azafen	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Azaphen (Pipofezin hydrochloride) 是一种 5-羟色胺重吸收抑制剂。
T1317	Cinchonidine 奎宁树,α-Quinidine,辛可尼丁,L-Cinchonidine	5-HT Receptor; Serotonin Transporter; Parasite	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Cinchonidine (L-Cinchonidine) 是在金鸡纳和角蒿中发现的一种生物碱，有抗疟活性。它是用于有机化学中不对称合成的砌块，是血清素转运蛋白的弱抑制剂。
T0185	Escitalopram Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Escitalopram (Seroplex) 是一种外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂，Ki=0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性，是一种研究抑郁症的抗抑郁药。

天然产物

Cat.No: T7521

Synonym: Pipofezin hydrochloride,阿扎吩,Pipofezine hydrochloride,Azafen

Target: 5-HT Receptor, Serotonin Transporter

Cat.No: T1317

Synonym: 奎宁树,α-Quinidine,辛可尼丁,L-Cinchonidine

Target: 5-HT Receptor, Serotonin Transporter, Parasite

Cat.No: T0185

Synonym: Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc) SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His) V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi) MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05387

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05547

Species: Human

Expression System: HEK293 Cells

SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05498

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00854

Species: Human

Expression System: E. coli

SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01357

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01363

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼