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L-690330
还可以产品编号 T15685Cas号 142523-38-4
L-690330 is a competitive inositol monophosphatase inhibitor (Kis: 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase). L-690330 shows 10-fold more sensitive than a mouse and rat IMPase.
L-690330
还可以产品编号 T15685Cas号 142523-38-4
L-690330 is a competitive inositol monophosphatase inhibitor (Kis: 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase). L-690330 shows 10-fold more sensitive than a mouse and rat IMPase.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 789 | 5日内发货 | |
| 5 mg | ¥ 1,330 | 5日内发货 | |
| 25 mg | ¥ 5,300 | 6-8周 | |
| 50 mg | ¥ 6,890 | 6-8周 | |
| 100 mg | ¥ 11,200 | 6-8周 | |
| 1 mL x 10 mM (in DMSO) | ¥ 1,460 | 5日内发货 |
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生物活性
化学信息
| 产品描述 | L-690330 is a competitive inositol monophosphatase inhibitor (Kis: 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase). L-690330 shows 10-fold more sensitive than a mouse and rat IMPase. |
| 靶点活性 | IMPase (bovine recombinant):0.19 μM(ki), IMPase (bovine frontal cortex):0.42 μM, IMPase (human frontal cortex):0.30 μM(ki), IMPase (human recombinant):(ki)0.27 μM |
| 体外活性 | In HEK293 cells, L-690330 (50 μM; 1 hour) causes P-AMPK and autophagy and increases LC3-I/II and p-AMPK expression[2]. |
| 体内活性 | Except for a reduction in time spent in light in the dark/light test, L-690330 (intracerebroventricular?injection; 0.1 μmol) shows no effects on their motor activity and coordination in the beam walking [3]. |
| 分子量 | 298.12 |
| 分子式 | C8H12O8P2 |
| CAS No. | 142523-38-4 |
| 密度 | 1.31g/cm3 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| 溶解度信息 | H2O: 33.33 mg/mL (111.80 mM), Sonication is recommended. DMSO: 25 mg/mL (83.86 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
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