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TMPJ-00735
|
PDGF-BB Protein, Human, Recombinant
PDGF-BB,血小板源生长因子,PDGFBB
|
Human
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E. coli
|
|
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In a... |
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TMPY-02185
|
Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
Coagulation factor 13,coagulation factor XIII, B polypeptide...
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Human
|
HEK293 Cells
|
|
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en... |
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TMPJ-00562
|
PDGF-BB Protein, Mouse, Recombinant (His)
PDGFBB,PDGF-BB,血小板源生长因子
|
Mouse
|
E. coli
|
|
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor，it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival... |
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TMPJ-00037
|
FGF-2 Protein, Mouse, Recombinant
Fibroblast Growth Factor 2,bFGF,HBGF-2,Basic Fibroblast Grow...
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Mouse
|
E. coli
|
|
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari... |
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TMPY-01061
|
FGF-10 Protein, Human, Recombinant
fibroblast growth factor 10,KGF2
|
Human
|
E. coli
|
|
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla... |
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TMPH-02831
|
PLET1 Protein, Mouse, Recombinant (His & SUMO)
Plet1,Placenta-expressed transcript 1 protein,Antigen mAgK11...
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Mouse
|
E. coli
|
|
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. |
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TMPH-02830
|
PLET1 Protein, Mouse, Recombinant (His)
Plet1,Placenta-expressed transcript 1 protein,Antigen mAgK11...
|
Mouse
|
Baculovirus Insect Cells
|
|
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. |
|
TMPH-01865
|
PLET1 Protein, Human, Recombinant (His)
PLET1,Placenta-expressed transcript 1 protein
|
Human
|
E. coli
|
|
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q6UQ28. |
|
TMPH-01866
|
PLET1 Protein, Human, Recombinant (His & Myc)
Placenta-expressed transcript 1 protein,PLET1
|
Human
|
Baculovirus Insect Cells
|
|
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.3 kDa and the accession number is Q6UQ28. |
|
TMPH-02594
|
MMP-13 Protein, Mouse, Recombinant (His)
Matrix metalloproteinase-13,Collagenase 3,Mmp13
|
Mouse
|
E. coli
|
|
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone develop... |
|
TMPH-01297
|
DDR1 Protein, Human, Recombinant (aa 21-417, His)
EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...
|
Human
|
HEK293 Cells
|
|
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell... |
|
TMPH-01974
|
Prothrombin Protein, Human, Recombinant (His)
F2,Coagulation factor II,Prothrombin
|
Human
|
P. pastoris (Yeast)
|
|
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Prothrombin Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is P00734. |
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TMPJ-00271
|
SMAD3 Protein, Human, Recombinant (His & Flag)
SMAD 3,Mothers against DPP homolog 3,hMAD-3,MADH3,JV15-2,SMA...
|
Human
|
E. coli
|
|
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so doing transduce the signal into the nucleus. Receptor-regulated SMAD is an intracellular signal transducer and transcriptional modulator activated by TGF-beta and activin type 1 receptor kinases. SMAD3 binds the TRE element in the promoter region of many genes that are regulated... |
|
TMPY-02838
|
FGFBP3 Protein, Human, Recombinant (His)
C10orf13,FGF-BP3,fibroblast growth factor binding protein 3
|
Human
|
Baculovirus Insect Cells
|
|
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are important regulators of cell migration, proliferation and differentiation, e.g., during embryogenesis and wound healing, and under several pathological conditions including tumor growth and tumor angiogenesis. Expression of FGF-BP increases after injury to murine and human skin, in p... |
|
TMPK-01334
|
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
Basigin,BSG,M6,OK,5F7,TCSF,CD147
|
Canine
|
HEK293 Cells
|
|
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners. |
|
TMPY-04801
|
Fibromodulin Protein, Human, Recombinant (hFc)
FM,fibromodulin,SLRR2E
|
Human
|
HEK293 Cells
|
|
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therap... |
|
TMPH-03598
|
Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)
SPE B,Streptococcus peptidase A,Streptopain,Streptococcal cy...
|
Streptococcus pyogenes
|
E. coli
|
|
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) is expressed in E. coli expression system with... |
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TMPH-02835
|
PDGFD Protein, Mouse, Recombinant (His & SUMO)
Platelet-derived growth factor D,Pdgfd,Spinal cord-derived g...
|
Mouse
|
E. coli
|
|
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including inf... |
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TMPH-03599
|
Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)
Group A streptococcal cysteine protease,SPE B,Streptococcus ...
|
Streptococcus pyogenes
|
E. coli
|
|
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO... |
|
TMPY-01846
|
Activin A Protein, Mouse, Recombinant (His)
inhibin, β A,inhibin, beta A
|
Mouse
|
HEK293 Cells
|
|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in... |
|
TMPK-00368
|
MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated
Gelatinase B,MMP-9,MANDP2,CLG4B,GELB
|
Human
|
HEK293 Cells
|
|
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina... |
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TMPK-00503
|
MMP-9 Protein, Cynomolgus, Recombinant (His)
MMP-9,CLG4B,Gelatinase B,MANDP2,GELB
|
Cynomolgus
|
HEK293 Cells
|
|
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Cynomolgus, Reco... |
|
TMPK-00367
|
MMP-9 Protein, Human, Recombinant (His & Avi)
MANDP2,CLG4B,Gelatinase B,GELB,MMP-9
|
Human
|
HEK293 Cells
|
|
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina... |
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TMPK-01044
|
VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated
血管内皮生长因子,Flt4-L,VRP,VEGF-C,VEGFC
|
Human
|
HEK293 Cells
|
|
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes. VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mam... |
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TMPY-01190
|
INHBB Protein, Human, Recombinant (His)
inhibin beta B,INHBB,Inhibin β B Protein,MGC157939,inhibin β...
|
Human
|
HEK293 Cells
|
|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two ß subunits, ßA ßA (activin A), ßB ßB (activin B), or ßA ßB (activin AB). Inhibin is composed of an alpha and one of two ß subunits, ßA (inhibin A) or ßB (inhibin B). Activins are produced in... |
|
TMPK-01043
|
VEGFC Protein, Human, Recombinant (His & Avi)
Flt4-L,血管内皮生长因子,VEGFC,VRP,VEGF-C
|
Human
|
HEK293 Cells
|
|
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes. VEGFC Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells w... |
|
TMPJ-00447
|
MMP-3 Protein, Human, Recombinant (His)
Transin-1,Stromelysin-1,MMP-3,Matrix metalloproteinase-3,MMP...
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Human
|
HEK293 Cells
|
|
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 c... |
|
TMPY-00371
|
STC1 Protein, Human, Recombinant (His)
stanniocalcin 1,STC
|
Human
|
HEK293 Cells
|
|
Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has myriad functions, including the maintenance of calcium homeostasis, the promotion of early wound healing, uncoupling respiration (aerobic glycolysis), reepithelialization in damaged tissues, the inhibition of vascular leakage, and the regulation of macrophage functions to keep e... |
|
TMPJ-01433
|
Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated
Fibronectin,FN1
|
Human
|
E. coli
|
|
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, an... |
|
TMPJ-00012
|
CXCL4 Protein, Human, Recombinant (His)
SCYB4,PF4,Iroplact,Platelet Factor 4,PF-4,Oncostatin-A,CXCL4...
|
Human
|
HEK293 Cells
|
|
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokin... |
|
TMPJ-00771
|
TGF beta 1 Protein, Mouse/Rat, Recombinant
TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-beta 1 protein,latency-as...
|
Mouse,Rat
|
HEK293 Cells
|
|
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)... |
|
TMPY-03419
|
SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)
SMAD family member 3
|
Human,Mouse,Rat
|
Baculovirus Insect Cells
|
|
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is involved in cell signalling. It modulates signals of activin and TGFβ's. Binding of SMAD3 with SMAD4 enables its transmigration into the nucleus where it forms complexes with other proteins and acts as a transcription factor. SMAD3 is a receptor-regulated SMAD (R-SMAD). In mice,... |
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TMPJ-01177
|
NOV/CCN3 Protein, Mouse, Recombinant (His)
CCN family member 3,Nephroblastoma-overexpressed gene protei...
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Mouse
|
HEK293 Cells
|
|
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and ... |
|
TMPJ-00304
|
ALK-1 Protein, Mouse, Recombinant (hFc)
TSR-I,Serine/threonine-protein kinase receptor R3,ALK-1,SKR3...
|
Mouse
|
HEK293 Cells
|
|
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angiogenesis during embryogenesis, wound healing, and tumor growth. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. ALK-1... |
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TMPY-01484
|
THSD1 Protein, Mouse, Recombinant (His)
4833423O18Rik,thrombospondin type 1 domain containing 1,Tmts...
|
Mouse
|
HEK293 Cells
|
|
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to a... |
|
TMPJ-01089
|
TFF1 Protein, Mouse, Recombinant (His)
Bcei,Protein pS2,Ps2,Trefoil factor 1,Tff1
|
Mouse
|
HEK293 Cells
|
|
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing.It originates from musculus and highly expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and fo... |
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TMPH-03753
|
MYLK Protein, Human, Recombinant (His)
MYLK,Myosin light chain kinase, smooth muscle,Telokin,Kinase...
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Human
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E. coli
|
|
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl... |
|
TMPJ-00802
|
THBS1 Protein, Human, Recombinant (His)
TSP,TSP1,Thrombospondin-1,THBS1
|
Human
|
HEK293 Cells
|
|
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 contains an N-terminal Laminin G-like globular domain, an extended central region with one vWFC domain, 3 TSP type 1domains, 2 EGF-like domains, and 8 TSP type3 domains, and a globular TSP C-terminal domain. Distinct regions of TSP-1 have... |
|
TMPJ-00534
|
hFcgR4 Protein, Mouse, Recombinant (His)
Low Affinity Immunoglobulin γ Fc Region Receptor IV,FcgR4,Lo...
|
Mouse
|
HEK293 Cells
|
|
Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of sensory perception of pain, wound healing etc. Three groups are included for Fc γ receptors (FcR), and they are Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). Among these, CD64 possess high affinity even for monomeric IgG, while CD32 and CD16 display a relative lower affinity ... |
|
TMPY-02174
|
FABP5 Protein, Human, Recombinant
PA-FABP,E-FABP,fatty acid binding protein 5 (psoriasis-assoc...
|
Human
|
E. coli
|
|
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is pre... |
|
TMPY-01680
|
Lumican Protein, Human, Recombinant (His)
lumican,LDC,SLRR2D
|
Human
|
HEK293 Cells
|
|
Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican regulates collagenous matr... |
|
TMPY-00741
|
CXCL4 Protein, Human, Recombinant
PF-4,platelet factor 4,SCYB4,CXCL4
|
Human
|
E. coli
|
|
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a... |
|
TMPJ-00535
|
F13A Protein, Human, Recombinant (His)
F13A1,Coagulation Factor XIII A Chain,Transglutaminase A Cha...
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Human
|
HEK293 Cells
|
|
Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium io... |
|
TMPY-02760
|
CALML3 Protein, Human, Recombinant (His)
calmodulin-like 3,CLP
|
Human
|
E. coli
|
|
Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a tumor-sensitive protein specifically expressed in normal epithelial cells but downregulated in tumorigenesis. Downregulation of the protein is an early event in breast cancer development. One of the most pressing questions raised by the discovery of CLP/CALML3 is that of its pote... |
|
TMPY-02246
|
HB-EGF Protein, Human, Recombinant
DTSF,DTR,HEGFL,heparin-binding EGF-like growth factor,DTS
|
Human
|
Baculovirus Insect Cells
|
|
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of... |
|
TMPH-02524
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Arginase-1/ARG1 Protein, Mouse, Recombinant (His)
Arginase-1,Type I arginase,Liver-type arginase,Arg1
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Mouse
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P. pastoris (Yeast)
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Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.; Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available i... |
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TMPY-01212
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ADAM12 Protein, Human, Recombinant (His)
ADAM metallopeptidase domain 12,MLTNA,MCMP,CAR10,MLTN,MCMPMl...
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Human
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HEK293 Cells
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The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities. Human ADAM12, which is implicated in diseases such as cancer, is expressed in two splice forms, the transmembrane ADAM12-L and the shorter and soluble ADAM12-S. ADAM12, also known as and Meltrin alpha, is a member of the ADAM protein family, which contains one disintegrin domain, one EGF-like domain and one peptidase M12B domain. ADAM12 is synthes... |
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