|
TMPY-02779
|
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
thyroid peroxidase,MSA,TPX,TDH2A
|
Human
|
Baculovirus Insect Cells
|
|
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i... |
|
TMPK-00874
|
Thyroid Peroxidase Protein, Mouse, Recombinant (His)
MK-CSF,MGDF,ML,MPLLG,THPO,TPOMKCSF,Thrombopoietin,MKCSF,MGDF...
|
Mouse
|
HEK293 Cells
|
|
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune t... |
|
TMPY-06821
|
THRB Protein, Human, Recombinant (His)
THRB1,GRTH,THR1,ERBA2,C-ERBA-2,THRB2,thyroid hormon...
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Human
|
E. coli
|
|
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-binding domain, THRB isoform 1/2 expression localizes predominately to the liver and pituitary, respectively. THRB regulates the feedback of T3-dependent thyrotropin-stimulating hormone (TSH) transcription in the pituitary by binding to thyroid hormone (TH) response elements present... |
|
TMPY-04127
|
CIp4 Protein, Human, Recombinant (His)
CIP4,thyroid hormone receptor interactor 10,STOT,ST...
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Human
|
Baculovirus Insect Cells
|
|
CIp4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 64 kDa and the accession number is Q15642-2. |
|
TMPH-03386
|
TSHB Protein, Rat, Recombinant (E. coli, His & Myc)
Thyrotropin beta chain,Tshb,Thyrotropin subunit beta,Thy...
|
Rat
|
E. coli
|
|
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 19.9 kDa and the accession number is P04652. |
|
TMPH-03387
|
TSHB Protein, Rat, Recombinant (His & Myc)
Thyrotropin subunit beta,Thyroid-stimulating hormon...
|
Rat
|
P. pastoris (Yeast)
|
|
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession number is P04652. |
|
TMPH-01908
|
JMJD1C Protein, Human, Recombinant (His & Myc & SUMO)
Probable JmjC domain-containing histone demethylation protei...
|
Human
|
E. coli
|
|
JMJD1C Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli. |
|
TMPH-02204
|
THRB Protein, Human, Recombinant (His & SUMO)
c-erbA-beta,THRB,Thyroid hormone receptor beta,c-er...
|
Human
|
E. coli
|
|
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. |
|
TMPH-01273
|
TRIP12 Protein, Human, Recombinant (His & Myc)
Thyroid receptor-interacting protein 12,E3 ubiquiti...
|
Human
|
E. coli
|
|
E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damag... |
|
TMPH-02203
|
THRA Protein, Human, Recombinant (His)
c-erbA-1,c-erbA-alpha,THRA,Thyroid hormone receptor...
|
Human
|
E. coli
|
|
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.; Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action. THRA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is P10827. |
|
TMPH-01648
|
MED1 Protein, Human, Recombinant (His & SUMO)
Activator-recruited cofactor 205 kDa component,Mediator comp...
|
Human
|
E. coli
|
|
MED1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.2 kDa and the accession number is Q15648. |
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TMPH-00848
|
OASL Protein, Human, Recombinant (His)
59 kDa 2'-5'-oligoadenylate synthase-like protein,Thyroi...
|
Human
|
E. coli
|
|
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. OASL Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.1 kDa and the accession number is Q15646. |
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TMPH-00488
|
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His)
Follicle-stimulating hormone alpha chain,Glycoprotein hormon...
|
Canine
|
P. pastoris (Yeast)
|
|
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His) is expressed in Yeast. |
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TMPH-03370
|
Serpin A3K Protein, Rat, Recombinant (His & Myc)
GHR-P63,Thyroid hormone-regulated protein,Contrapsi...
|
Rat
|
E. coli
|
|
Binds to and inhibits kallikreins. Inhibits trypsin but not chymotrypsin or elastase. Serpin A3K Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 52.0 kDa and the accession number is P05545. |
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TMPH-00489
|
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His & Myc)
Follitropin alpha chain,CGA,Luteinizing hormone alpha chain,...
|
Canine
|
E. coli
|
|
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His & Myc) is expressed in E. coli. |
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TMPH-02314
|
XRCC5 Protein, Human, Recombinant (His & MBP)
Nuclear factor IV,Lupus Ku autoantigen protein p86,ATP-depen...
|
Human
|
Baculovirus Insect Cells
|
|
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... |
|
TMPH-02315
|
XRCC5 Protein, Human, Recombinant (His & Myc)
ATP-dependent DNA helicase 2 subunit 2,XRCC5,Ku86,Nuclear fa...
|
Human
|
E. coli
|
|
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... |
|
TMPY-04853
|
TSHR Protein, Human, Recombinant (His)
TSHR,hTSHR-I,TSH Receptor,LGR3,CHNG1
|
Human
|
Baculovirus Insect Cells
|
|
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis. |
|
TMPY-02287
|
Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)
KARP1,XRCC5 & XRCC6,KUB2,KU80,KARP-1,Ku86,NFIV
|
Human
|
Baculovirus Insect Cells
|
|
X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repair protein XRCC5, Lupus Ku autoantigen protein p86, TLAA and XRCC5, is a nucleus and chromosome which belongs to the ku8 family. XRCC5 is a single-stranded DNA-dependent ATP-dependent helicase. XRCC5 has a role in chromosome translocation. X-ray repair cross-complementing protein... |
|
TMPY-03502
|
PAX8 Protein, Human, Recombinant (His)
paired box 8
|
Human
|
E. coli
|
|
PAX8 gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 is involved in thyroid follicular cell development and expression of thyroid-specific genes. Also functions in very early stages of kidney organogenesis. Mutations in PAX8 gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyr... |
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TMPH-03262
|
Cathepsin K Protein, Rat, Recombinant (His)
CTSO,CTSO2,Cathepsin O2,Cathepsin X,Cathepsin O,CTSK,Catheps...
|
Rat
|
E. coli
|
|
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. |
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TMPH-02685
|
GPHB5 Protein, Mouse, Recombinant (His & Myc)
Glycoprotein hormone beta-5,Thyrostimulin subunit beta,Gphb5
|
Mouse
|
E. coli
|
|
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. |
|
TMPH-02947
|
Transthyretin Protein, Mouse, Recombinant
Prealbumin,Transthyretin,Ttr
|
Mouse
|
E. coli
|
|
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.5 kDa and the accession number is P07309. |
|
TMPH-02684
|
GPHB5 Protein, Mouse, Recombinant (His)
Thyrostimulin subunit beta,Glycoprotein hormone beta-5,Gphb5
|
Mouse
|
P. pastoris (Yeast)
|
|
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. GPHB5 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.3 kDa and the accession number is Q812B2. |
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TMPH-02242
|
Transthyretin Protein, Human, Recombinant (hFc & Myc)
TTR,ATTR,Transthyretin,Prealbumin,TBPA
|
Human
|
HEK293 Cells
|
|
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. |
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TMPH-02565
|
Cathepsin K Protein, Mouse, Recombinant (His)
Cathepsin O,Cathepsin K,CTSK,Cathepsin O2,CTSO2,Cathepsin X,...
|
Mouse
|
E. coli
|
|
Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Cathepsin K Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is P... |
|
TMPH-01061
|
Cathepsin K Protein, Human, Recombinant (His)
CTSO2,Cathepsin X,Cathepsin O2,CTSK,Cathepsin O,Cathepsin K,...
|
Human
|
E. coli
|
|
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Cathepsin K Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pre... |
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TMPH-03385
|
Thyroglobulin Protein, Rat, Recombinant (His & SUMO)
Tg,Thyroglobulin
|
Rat
|
E. coli
|
|
Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. Thyroglobulin Protein, Rat, Recombin... |
|
TMPY-01584
|
PR-Set7 Protein, Human, Recombinant
SET8,SET07,PR-Set7,SET domain containing (lysine methyltrans...
|
Human
|
E. coli
|
|
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was significantly correlated with extrathyroidal extension, lymph node metastasis and advanced pathological stage of papillary thyroid cancer. KMT5A may be a novel oncogenic factor, specifically a re... |
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TMPH-02120
|
SLC5A5 Protein, Human, Recombinant (His)
Sodium-iodide symporter,SLC5A5,Natrium iodide transporter,So...
|
Human
|
E. coli
|
|
Mediates iodide uptake in the thyroid gland. SLC5A5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession number is Q92911. |
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TMPH-01251
|
DUSP26 Protein, Human, Recombinant (His & SUMO)
MKP-8,NATA1,DSP-4,SKRP3,DUSP26,MKP8,LDP-4,LDP4,DUSP24,Dual s...
|
Human
|
E. coli
|
|
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |
|
TMPH-02946
|
Transthyretin Protein, Mouse, Recombinant (His & SUMO)
Transthyretin,Prealbumin,Ttr
|
Mouse
|
E. coli
|
|
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.6 kDa and the accession number is P07309. |
|
TMPH-01059
|
Cathepsin B Protein, Human, Recombinant (GST)
Cathepsin B1,APPS,Cathepsin B,CPSB,APP secretase,CTSB
|
Human
|
E. coli
|
|
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. Cathepsin B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.6 kDa and the accession number is P07858. |
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TMPY-00483
|
Parvalbumin/PVALB Protein, Human, Recombinant (His)
parvalbumin,D22S749
|
Human
|
E. coli
|
|
Parvalbumins (PVALBs) are particularly abundant in the fast-contracting muscles and correlate positively with muscle relaxation speed in amphibians and fishes. The loss of PVALB plays a role in the pathogenesis of thyroid tumors. The mutations in the PVALB gene are not involved in GS patients who harbour a single or no mutant SLC12A3 allele. |
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TMPJ-01319
|
TINAGL1 Protein, Human, Recombinant (His)
LCN7,Tubulointerstitial nephritis antigen-like (TINAGL1),Oxi...
|
Human
|
HEK293 Cells
|
|
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so on. TINAGL1 may be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. |
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TMPJ-00656
|
SULT1C2 Protein, Human, Recombinant (His)
Sulfotransferase 1C1,humSULTC2,SULT1C1,Sulfotransferase 1C2,...
|
Human
|
E. coli
|
|
Sulfotransferase 1C2 (SULT1C2) is a cytosolic enzyme member of the Sulfotransferase 1 family. Human SULT1C2 is primarily expressed in the adult stomach, kidney and thyroid gland, and in the fetal kidney and liver. SULT1C2 catalyzes the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. SULT1C2 may be involved in the activation of carcinogenic hyroxylamines. It shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). |
|
TMPH-03377
|
SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO)
DOPA/tyrosine sulfotransferase,Sult1b1,Sulfotransferase fami...
|
Rat
|
E. coli
|
|
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is P... |
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TMPY-01617
|
SULT1B1 Protein, Human, Recombinant (His)
sulfotransferase family, cytosolic, 1B, member 1,SULT1B2,ST1...
|
Human
|
E. coli
|
|
Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1B1 is highly expressed in the liver, perip... |
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TMPJ-00705
|
BCAS2 Protein, Human, Recombinant (His, T7)
BCAS2,DNA Amplified in Mammary Carcinoma 1 Protein,Pre-mRNA-...
|
Human
|
E. coli
|
|
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator ... |
|
TMPJ-00793
|
TPM3 Protein, Human, Recombinant
Tropomyosin α-3 Chain,γ-Tropomyosin,hTM5,Tropomyosin Alpha-3...
|
Human
|
E. coli
|
|
Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are... |
|
TMPY-04445
|
PDK4 Protein, Mouse, Recombinant (His & GST)
AV005916,pyruvate dehydrogenase kinase 4
|
Mouse
|
Baculovirus Insect Cells
|
|
Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient availability.Pyruvate dehydrogenase kinase 4 (PDK4) mRNA has been reported as an up-regulated gene in the heart and skeletal muscle of carnitine-deficient juvenile visceral steatosis (JVS) mice under fed conditions. PDK4 plays an important role in the inhibition of glucose oxida... |
|
TMPY-03613
|
COMMD8 Protein, Human, Recombinant (His)
COMM domain containing 8
|
Human
|
E. coli
|
|
COMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein interactions. Most COMMD proteins play a role in the regulation of NF˚B and, despite their similarities, seem to function in unique and non-redundant pathways. COMMD proteins may also play a role in the function of epithelial sodium channels, cell proliferation, copper homeostasis a... |
|
TMPY-02394
|
IMPA1 Protein, Human, Recombinant (His)
IMPA,inositol(myo)-1(or 4)-monophosphatase 1,IMP
|
Human
|
E. coli
|
|
IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Ad... |
|
TMPJ-00701
|
Carbonic Anhydrase 11 Protein, Human, Recombinant (His)
Carbonic Anhydrase-Related Protein 2,CARP XI,CA11,CARP-2,Car...
|
Human
|
HEK293 Cells
|
|
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA11 is expressed abundantly in the brain with moder... |
|
TMPY-03811
|
KCT2 Protein, Human, Recombinant (His)
chromosome 5 open reading frame 15,KCT2,HTGN29
|
Human
|
HEK293 Cells
|
|
C5orf15 (Chromosome 5 Open Reading Frame 15, also known as KCT2) is a Protein Coding gene. KCT2 gene maps to human chromosome 5q31.1 and is conserved in human, chimpanzee, cow, rat, and chicken. KCT2 is a 265 amino acid single-pass type I membrane protein that is widely expressed in the thyroid, kidney, and other tissues. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. ... |
|
TMPJ-01260
|
WBP2 Protein, Human, Recombinant (His)
WBP2,WW Domain-Binding Protein 2,WBP-2
|
Human
|
E. coli
|
|
WW Domain-Binding Protein 2 (WBP2) is a ubiquitous protein that contains one GRAM domain. The WW domain is composed of 38 to 40 semi-conserved AA shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is participated in mediating protein-protein interactions. WBP2 binds to the WW domain of YAP1, WWP1 and WWP2. The WW-binding 1 motif of WBP2 mediates interaction with NEDD4. The function of this protein WBP2 has not been determined. Some resear... |
|
TMPY-03280
|
RAMP3 Protein, Human, Recombinant (hFc)
receptor (G protein-coupled) activity modifying protein 3
|
Human
|
HEK293 Cells
|
|
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transp... |
|
TMPJ-00456
|
APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
TRDL-1,TNFSF13,CD256,TALL-2,A proliferation-inducing ligand
|
Mouse
|
HEK293 Cells
|
|
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissu... |
|
TMPY-01551
|
Serpin B8 Protein, Mouse, Recombinant (His)
CAP-2,serpin peptidase inhibitor, clade B (ovalbumin), membe...
|
Mouse
|
Baculovirus Insect Cells
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Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal... |
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TMPY-01451
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MESDC2 Protein, Human, Recombinant (His)
MESD,mesoderm development candidate 2,BOCA
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Human
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HEK293 Cells
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MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside... |
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