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Search Results for " scavenging "

Targets Recommended: Apoptosis Others Lipoxygenase

45

抑制剂 & 化合物

159

天然产物

1

化合物库

5

重组蛋白

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Cat. No.	Product Name
L6120	黄酮类天然产物库		514 compounds
	514 种黄酮类天然产物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

黄酮类天然产物库

Cat.No: L6120

Compounds: 514

Cat. No.	Product Name	Target	Signaling Pathways
T8794	4-MMPB 15-Lipoxygenase Inhibitor 1	Apoptosis; Others; Lipoxygenase	Apoptosis; Metabolism; Others
	4-MMPB (15-Lipoxygenase Inhibitor 1) 是一种选择性15-脂氧合酶抑制剂，其 IC50值为 18 μM，具有前列腺癌的研究潜力。它对大豆 15-脂氧合酶和人 15-脂氧合酶-1 的 IC50 分别为 19.5 μM 和 19.1 μM。
T40612	Manganese(salen) chloride EUK-8	Others	Others
	Manganese(salen) chloride (EUK-8) 是超氧化物歧化酶和过氧化氢酶的一种模拟物，具有氧自由基清除性能。它可减轻内毒素血症猪的急性肺损伤。
T1229	Erdosteine 厄多司坦,RV 144,KW-9144	NF-κB; Antibacterial; Adenosine deaminase	Metabolism; Microbiology/Virology; NF-κB
	Erdosteine (RV 144) 抑制脂多糖诱导的NF-κB 激活，具有粘液调节、抗菌、抗炎、抗氧化和自由基清除作用。
T3289	Amifostine 氨磷汀,Ethyol,WR2721,Gammaphos	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Amifostine (Ethyol) 是一种广谱细胞保护剂和辐射防护剂，具有清除自由基的作用。它可选择性保护正常组织免受放射线和化学疗法造成的损害。它是有效的 HIF-α1和 p53诱导剂，可降低肾脏毒性并具有抗血管生成作用。
T17111	Todralazine hydrochloride Ecarazine hydrochloride,盐酸托屈嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Todralazine hydrochloride (Ecarazine hydrochloride) 是一种 β2AR 阻滞剂，具有抗氧化和自由基清除活性。 Todralazine hydrochloride 可用于抗高血压的研究。
T41345	AFMK Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine	Apoptosis; Free radical scavengers; Antioxidant; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	AFMK (Formyl-N-acetyl-5-methoxykynurenamine) 是褪黑激素的活性代谢物，具有抗氧化和自由基清除活性。 AFMK 是一种凋亡调节剂，可提高吉西他滨在 PANC-1 细胞中的抗肿瘤作用。
T78554	Tyrosinase-IN-12	Tyrosinase	Proteases/Proteasome
	Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) 是一种有效的非竞争性酪氨酸酶抑制剂，IC50 值为 49.33 ± 2.64 µM，Ki 值为31.25 ± 0.25 µM。Tyrosinase-IN-12 具有显著的抗氧化和自由基清除活性，减少活性氧 (ROS) 的产生（IC50:25.39 ± 0.77 µM)。Tyrosinase-IN-12 可用于研究食品和水果中物质的褐变。
T63750	α-Amylase-IN-1	Antioxidant; Amylase	Metabolism; oxidation-reduction
	α-Amylase-IN-1 是一种 α-Amylase 抑制剂（ IC50： 0.5509 μM）。α-Amylase-IN-1 具有抗氧化 (antioxidant) 活性，清除 DPPH 自由基的 IC50 值为 53.49 μM，可用于研究糖尿病和氧化应激相关疾病。
T9560	MAO-B-IN-2	Others	Others
	MAO-B-IN-2 是一种选择性和竞争性的MAO-B 和 BChE 抑制剂，其IC50值分别为 0.51 和 7.00 μM。MAO-B-IN-2 通过良好的 ROS 清除特性减轻 H2O2 诱导的细胞损伤。
T23046	N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮	ROS; COX	Immunology/Inflammation; Neuroscience
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) 是基于硝酮的自由基清除剂，可形成一氧化氮自旋加合物。它可以穿透血脑屏障，抑制 COX2的催化活性，有 ROS 清除、抗炎、神经保护、抗衰老和抗糖尿病的作用。
T77578	CHBO4	MAO; ROS	Immunology/Inflammation; Metabolism; Neuroscience
	CHBO4 是一种 hMAO-B 抑制剂，具有强效性、可逆性、竞争性和选择性。CHBO4 在 CHBO 实验中对 hMAO-B 的 IC50 值为 0.031 μM， Ki 值为 0.010 ± 0.005 μM。CHBO4 通过清除细胞内活性氧 (ROS) 减少细胞损伤，可用于研究帕金森病 (PD) 。
T12781	RV01	Others	Others
	RV01 是一种新型的白藜芦醇喹啉取代类似物，可抑制 DNA 损伤，降低乙醇诱导的乙醛脱氢酶 (ALDH2) 的 mRNA 表达，具有清除羟自由基的活性。RV01 降低 iNOS 的表达，具有抗神经炎症作用。RV01降低肿瘤坏死因子-a (TNF-a)和白细胞介素-6 (IL-6) mRNA 水平和分泌，抑制lps 诱导的ROS 生成和烟酰胺腺嘌呤二核苷酸磷酸(NADPH)氧化酶活化，降低toll 样受体4 (TLR4)的蛋白表达，抑制lps 诱导的丝裂原活化蛋白激酶(MAPK)和核转录因子-кB (NF-кB)信号通路的激活。
T31834	FMHM	Others	Others
	FMHM is a TRAF6 scavenging agent via ubiquitination-dependent mode.
T17112	Todralazine Ecarazine	Others	Others
	Todralazine is an anti-hypertensive agent and acts as a β2AR blocker. It also has an antioxidant and free radical scavenging activity.
T71322	CV 6504	Others	Others
	CV 6504 is a dual inhibitor of thromboxane A2 synthetase and 5-lipoxygenase. It also possesses oxygen scavenging activity.
T23816	BPIC	Others	Others
	BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.
T76576	Arg-Tyr
	Arg-Tyr 是一种具有强羟自由基和过氧化氢清除活性的二肽。
T35964	MitoTEMPO hydrate	Others	Others
	MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.[1] This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. Mitochondrial targeting of superoxide scavenging via mitoTEMPO has been examined for potential therapeutic benefit to a variety of mitochondrial dysfunctions arising from...
T40979	XJB-5-131	Others	Others
	XJB-5-131 is a synthetic, bi-functional antioxidant specifically designed to target mitochondria for the scavenging of reactive oxygen species (ROS) and electrons, thereby acting as a radical scavenger. Additionally, it serves as an effective protector and mitigator against ionizing irradiation for cord blood mononuclear cells (CB MNCs).
T38945	Carboxy-PTIO	Others	Others
	Carboxy-PTIO is a highly effective nitric oxide (NO) scavenger known for its rapid reaction rate with NO, resulting in the formation of nitric dioxide (NO2). Its direct scavenging action against NO plays a crucial role in preventing hypotension and endotoxic shock, particularly in lipopolysaccharide-stimulated rat models.
T61579	BuChE-IN-5	Others	Others
	BuChE-IN-5 (compound 25b) is a highly potent BuChE inhibitor, displaying an IC50 value of 1.94 μM. It effectively inhibits aggregation of Aβ and tau protein in Escherichia coli. Furthermore, BuChE-IN-5 exhibits considerable free radical scavenging capacity and antioxidant activity. Given these properties, it holds promise as a valuable tool for Alzheimer's disease research [1].
T38646	GKT136901 hydrochloride GKT136901 hydrochloride	Others	Others
	GKT136901 hydrochloride is a powerful, selective, and orally active inhibitor of NADPH oxidase (NOX1/4). It exhibits K i values of 160 nM and 165 nM against NOX1 and NOX4, respectively. Additionally, GKT136901 hydrochloride demonstrates selectivity and direct scavenging ability towards peroxynitrite. This compound finds utility in studying diabetic nephropathy, stroke, neurodegeneration, and possesses anti-inflammatory properties.
T35590	Graphislactone A	Others	Others
	Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.
T81799	MHLWAAK TFA
	MHLWAAK TFA是从C-藻蓝蛋白胰酶水解产物中分离的抗氧化活性肽。它展现出了较强的DPPH和ABTS自由基清除效应，并且能保护斑马鱼幼虫免遭H2O2引发的氧化伤害。
T81827	MDYYFEER TFA
	MDYYFEER TFA为从C-藻蓝蛋白胰酶水解产物中提取的抗氧化活性肽，展现了显著的DPPH与ABTS自由基清除效果，并能保护斑马鱼幼虫免遭H2O2诱导的氧化伤害。
T81828	MDYYFEER
	MDYYFEER 是源自 C-藻蓝蛋白胰酶水解产物的抗氧化活性肽，能有效清除 DPPH 及 ABTS 自由基，并能保护斑马鱼幼虫免受 H2O2 诱导的氧化损害。
T81800	MHLWAAK
	MHLWAAK，抗氧化活性肽，源自C-藻蓝蛋白胰酶水解产物。该肽展现出显著DPPH及ABTS自由基清除效能，并能保护斑马鱼幼虫不受H2O2诱导的氧化损害。
T79603	3,7-DMF	TGF-beta/Smad	Stem Cells
	3,7-DMF作为一种口服活性抑制剂，有效抑制了TGF-β1诱导的HSC活化，并通过诱导抗氧化基因及淬灭ROS为研究肝纤维化提供了潜在应用。
T81864	MAQAAEYYR
	MAQAAEYYR 是从C-藻蓝蛋白的胰酶水解产物中分离得到的一种具备显著抗氧化活性的肽。它在DPPH和ABTS自由基清除实验中显示出较高的效率，并能有效保护斑马鱼幼虫免遭H2O2诱导的氧化伤害。
T81863	MAQAAEYYR TFA
	MAQAAEYYR TFA 是从 C-藻蓝蛋白胰酶水解产物中分离得到的一种具有高抗氧化活性的肽。它展现了显著的 DPPH 及 ABTS 自由基清除作用，并能有效保护斑马鱼幼虫不受 H2O2 诱导的氧化损伤。
T78067	Stobadine (-)-Stobadine	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Stobadine是一种抗氧化剂，能抑制自由基导致的内质网膜流动性变化，可作为基于抗氧化和清除自由基机制的心脏和神经保护剂研发的侯选药物[sup][1]。
T75501	Morin 3-O-β-D-glucopyranoside	Others	Others
	Morin 3-O-β-D-glucopyranoside 是一种天然类黄酮，具有抗真菌、抗癌和抗氧化活性。Morin 3-O-β-D-glucopyranoside 抑制逆转录酶、蛋白酪氨酸激酶和黄嘌呤氧化酶，还具有抗 HIV、抗动脉硬化和超氧化物清除活性。
T82408	Ferroptosis-IN-3	Ferroptosis	Apoptosis
	Ferroptosis-IN-3（Compound 25）是一款抑制RSL3引起的铁死亡（HT-1080细胞中EC50为8.6nM）的铁死亡抑制剂。此外，Ferroptosis-IN-3能有效清除DPPH和ABTS自由基（EC50分别为3.94μM与6.3μM），并且能降低脂质过氧化水平。
T79260	MCI	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	MCI具有针对性地清除活性氧(ROS)并降低环氧合酶-2(COX-2)表达的功能，COX-2的IC50值为1.23μM。在胶原诱导的关节炎(CIA)模型中展现出的抗炎效果明显，适用于类风湿性关节炎(RA)的研究。
T78817	AChE-IN-39	Others	Others
	AChE-IN-39（化合物7c）为一种高效AChE抑制剂，其IC50值为0.058 μM。该化合物展现出明显的DPPH清除活性，且能显著改善AlCl3诱导的遗忘症动物模型中的认知功能障碍，适用于阿尔茨海默病相关研究。
T83357	3-Hydroxy-2-(palmitoyloxy)propyl stearat	Others	Others
	3-Hydroxy-2-(palmitoyloxy)propyl stearate是一种从棕色巨藻Fucus virsoides J. Agardh的极性较小部分分离得到的非挥发性化合物。该化合物具有良好的自由基清除能力，并能保护斑马鱼胚胎免受过氧化氢诱导的氧化应激。
T35975	6,9-Dichloro-1,2,3,4-tetrahydroacridine	Others	Others
	6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3 1.Recanatini, M., Cavalli, A., Belluti, F., et al.SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylchol...
T61312	Antioxidant agent-3	Others	Others
	Antioxidant agent-3 (Compound 14q) 是一种抗氧化剂，具有有效的DPPH 自由基清除活性和ABTS+清除活性，IC50分别为 26.58 和 30.31 μM。Antioxidant agent-3 作用于 H2O2处理的 HepG2 细胞，可增加活性氧 (ROS)、超氧化物歧化酶 (SOD) 和谷胱甘肽 (GSH)，并减少乳酸脱氢酶(LDH)。
T60421	Antitumor agent-68	Others	Others
	Antitumor agent-68 是一种有效的微管蛋白抑制剂，具有良好的抗肿瘤活性，对宫颈癌细胞系 HeLa 和乳腺癌细胞系 MCF-7 细胞的IC50值分别为 3.6 和 3.8 μM。Antitumor agent-68 以剂量依赖的方式表现出良好的 ROS 和DPPH 自由基的清除活性。
T76598	H-Ser-Tyr-OH
	H-Ser-Tyr-OH是一种由谷氨酸、甘氨酸和组氨酸组成的二肽。它能与铜离子形成的铜（II）配合物生成，表现出较强的自由基清除活性。此外，H-Ser-Tyr-OH还能增加deltorphin这一δ阿片受体配体的细胞内摄取。
T81396	PRO-F
	PRO-F是一种光活化H2S供体，具备ROS清除功能。该化合物通过光激活能生成荧光信号，实现H2S释放的实时追踪；其激活过程不耗费内源性成分。PRO-F在细胞内提供H2S，以防止ROS过量造成的细胞损害，并已在慢性伤口愈合和糖尿病模型中展现出促进效果。
T36499	CuATSM	Others	Others
	The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic lateral sclerosis (ALS). Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that has traditionally been used in cellular imaging experiments to selectively label hypoxic tissue via its susceptibility ...
T78781	TrxR1-IN-1	Others	Others
	TrxR1-IN-1 (Compound 5j) 是一种具有针对性的TrxR1抑制剂，显示出IC50值为8.8 μM的抑制效能。该化合物在治疗癌症方面表现出潜在效果，其对多种癌细胞系的IC50值分别为：MCF-7细胞系1.5 μM、HeLa细胞系1.7 μM、BGC-823细胞系2.4 μM、SW-480细胞系2.8 μM和 A549细胞系2.1 μM。此外，TrxR1-IN-1还表现出了抗氧化特性，能有效清除DPPH自由基。
T60447	α-Amylase-IN-3	Others	Others
	α-Amylase-IN-3 (Compound 4) 是α-Amylase 的非竞争性型抑制剂，IC50值为 18.04 μM。α-Amylase-IN-3具有自由基清除活性，对DPPH 和ABTS 的IC50值分别为 16.04 μM 和 16.99 μM。α-Amylase-IN-3 显示出良好的 α-淀粉酶蛋白质-配体相互作用，可能具有抗氧化、抗炎等药理活性，有助于研究糖尿病和氧化应激相关疾病。
T72763	AChE/BuChE-IN-1	Others	Others
	AChE/BuChE-IN-1，一种白杨素衍生物，具备对丁酰胆碱酯酶（BuChE）的选择性抑制作用，其IC50值为0.48μM。对乙酰胆碱酯酶（AChE）的抑制IC50值为7.16μM。该化合物强效清除·OH，IC50仅为0.1674μM，能够抑制活性氧（ROS）、阻止Aβ1-42的聚集（自发、Cu2+诱导及AChE诱导）。AChE/BuChE-IN-1展现出高血脑屏障（BBB）渗透性、优良的生物利用度和低细胞毒性，是阿尔茨海默病（AD）研究领域的有力候选。

化合物

Cat.No: T8794

Synonym: 15-Lipoxygenase Inhibitor 1

Target: Apoptosis, Others, Lipoxygenase

Manganese(salen) chloride

Cat.No: T40612

Synonym: EUK-8

Target: Others

Cat.No: T1229

Synonym: 厄多司坦,RV 144,KW-9144

Target: NF-κB, Antibacterial, Adenosine deaminase

Cat.No: T3289

Synonym: 氨磷汀,Ethyol,WR2721,Gammaphos

Target: Others, HIF/HIF Prolyl-Hydroxylase

Todralazine hydrochloride

Cat.No: T17111

Synonym: Ecarazine hydrochloride,盐酸托屈嗪

Target: Adrenergic Receptor

Cat.No: T41345

Synonym: Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine

Target: Apoptosis, Free radical scavengers, Antioxidant, Endogenous Metabolite

Tyrosinase-IN-12

Cat.No: T78554

Target: Tyrosinase

α-Amylase-IN-1

Cat.No: T63750

Target: Antioxidant, Amylase

Cat.No: T9560

Target: Others

N-tert-butyl-α-Phenylnitrone

Cat.No: T23046

Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮

Target: ROS, COX

Cat.No: T77578

Target: MAO, ROS

Cat.No: T12781

Target: Others

Cat.No: T31834

Target: Others

Cat.No: T17112

Synonym: Ecarazine

Target: Others

Cat.No: T71322

Target: Others

Cat.No: T23816

Target: Others

Cat.No: T76576

MitoTEMPO hydrate

Cat.No: T35964

Target: Others

Cat.No: T40979

Target: Others

Cat.No: T38945

Target: Others

Cat.No: T61579

Target: Others

GKT136901 hydrochloride

Cat.No: T38646

Synonym: GKT136901 hydrochloride

Target: Others

Graphislactone A

Cat.No: T35590

Target: Others

Cat.No: T81799

Cat.No: T81827

Cat.No: T81828

Cat.No: T81800

Cat.No: T79603

Target: TGF-beta/Smad

Cat.No: T81864

Cat.No: T81863

Cat.No: T78067

Synonym: (-)-Stobadine

Target: Reactive Oxygen Species

Morin 3-O-β-D-glucopyranoside

Cat.No: T75501

Target: Others

Ferroptosis-IN-3

Cat.No: T82408

Target: Ferroptosis

Cat.No: T79260

Target: Reactive Oxygen Species

Cat.No: T78817

Target: Others

3-Hydroxy-2-(palmitoyloxy)propyl stearat

Cat.No: T83357

Target: Others

6,9-Dichloro-1,2,3,4-tetrahydroacridine

Cat.No: T35975

Target: Others

Antioxidant agent-3

Cat.No: T61312

Target: Others

Antitumor agent-68

Cat.No: T60421

Target: Others

Cat.No: T76598

Cat.No: T81396

Cat.No: T36499

Target: Others

Cat.No: T78781

Target: Others

α-Amylase-IN-3

Cat.No: T60447

Target: Others

AChE/BuChE-IN-1

Cat.No: T72763

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T9057	norbergenin	IL Receptor; TNF; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Norbergenin 是一种 bergenin 的邻去甲基衍生物，可从白芍的根茎中分离得到，具有中等的抗氧化活性。
T6S1440	Loganic acid 马钱苷酸,Loganate	Others	Others
	Loganic acid (Loganate) 是从山茱萸果实中分离得到的环烯醚萜。它具有很强的自由基清除活性，对重金属介导的毒性有显著的细胞保护作用。它能调节饮食引起的动脉粥样硬化和氧化还原状态。
T9135	Epirosmanol	Others	Others
	Epirosmanol 是含有内酯部分的二萜类化合物。 Epirosmanol 是一种极弱碱性（基本中性）的化合物（基于其 pKa）。
T3S0218	Thonningianin A	Apoptosis; Others	Apoptosis; Others
	Thonningianin A 是从非洲草药通宁宁的甲醇提取物中，分离得到的一种鞣花素，具有抗癌和抗氧化性，涉及自由基清除、抗超氧化物形成和金属螯合。
T2S1181	Aloenin Aloenin A,Aloearbonaside,芦荟宁	Beta-Secretase; AChR	Neuroscience
	Aloenin (Aloenin A) A 是一种具有清除过氧自由基作用的天然产物，对 β-分泌酶 (BACE) 具有中等抑制活性。
T22308	Dimboa 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one,丁布	Others; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology; Others
	Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) 是抗生素，是禾本科植物化学防御系统的一部分。它对许多已研究的细菌和真菌菌株具有生长抑制特性。它表现出强大的自由基清除活性和较弱的铁 (III) 离子还原活性和有抗氧化活性。
TN6706	3-demethylcolchicine 3-去甲秋水仙碱,3-去甲基秋水仙碱	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	3-Demethylcolchicine 是一种从金莲花中分离得到的天然产物，对纯化的牛脑微管蛋白的聚合有抑制作用。
T5728	OsMundacetone 4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Apoptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) 是从白桦茸中分离出的一种天然产物，具有抗凋亡作用。它具有DPPH 清除活性，保护神经细胞免受氧化应激，可研究神经退行性疾病。
TN2165	Rubrofusarin gentiobioside Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷	ERK; NF-κB; TGF-beta/Smad	MAPK; NF-κB; Stem Cells
	Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) 一种分离自决明子的、具有清除自由基作用的化合物。
T37710	5-Hydroxyoxindole	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	5-Hydroxyoxindole 是尿酸的一种结构类似物，具有脂质过氧化抑制活性和自由基 DPPH 清除活性，可用于氧化应激介导的疾病的研究。
TN6909	Polyporusterone B 猪苓酮B,(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one	Others	Others
	Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) 是一种三萜羧酸，从Polyporus umbellatusFries 中分离得到。它对自由基诱导的红细胞裂解 (溶血) 具有抑制作用。
T4S2084	3'-Methoxypuerarin 3'-甲氧基葛根素,3’- Methoxy Puerarin	Antioxidant	oxidation-reduction
	3'-Methoxypuerarin 是一种提取自葛根中的异黄酮，具有神经元保护作用。
T5S0281	Tubuloside A	NOS	Immunology/Inflammation
	Tubuloside A 是一种苯乙醇苷，具有抗氧化活性和保肝活性。
T7781	Reynoutrin Reinutrin,Quercetin-3-D-xyloside,槲皮素-3-D-木糖甙	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Reynoutrin (Reinutrin) 是一种黄酮类化合物，从草莓番石榴中得到，具有抗氧化清除自由基的活性。
T2936	Antiarol 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚	Others	Others
	Antiarol (3,4,5-trimethoxyphenol) 是一种提取自 Salmaliamalabaricum 中的天然化合物。
TN1916	Matairesinol 罗汉松树脂酚	ATPase; p38 MAPK; ROS	Immunology/Inflammation; MAPK; Membrane transporter/Ion channel
	Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells.
TN2008	Okanin	NF-κB; TLR	Immunology/Inflammation; NF-κB
	Okanin 是鬼针草中的一种有效成分，可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T3845	(+)-Gallocatechin Gallocatechol,没食子儿茶素没食子酸酯,D-Gallocatechin	Others	Others
	(+)-Gallocatechin (Gallocatechol) 是一种从绿茶中获得的多酚类化合物，具有抗癌作用。
TN1137	Isobutylshikonin	Others	Others
	Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。
T3828	(-)-Gallocatechin (2S,3R)-gallocatechin,(−)-GC,(-)-棓儿茶酸；没食子儿茶素,没食子儿茶素	Others	Others
	(-)-Gallocatechin ((−)-GC) 是一种 (-)-Epigallocatechin (EGC) 的差向异构体，常存在于各种茶产品中，具有抗氧化特性。
TN1002	Blumeatin	ROS	Immunology/Inflammation
	Blumeatin 是从Blumea balsamiferaDC 中分离得到，对 CCl4 和硫代乙酰胺 (TAA) 所致的肝损伤表现出保护活性。
TN1513	Clitorin 碟豆宁,碟豆素	PKC; Antifection	Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology
	Clitorin 是一种山奈酚糖苷，分离自 Acalypha indica 的花和叶，表现出抗氧化活性。
T3905	Isomangiferin	Free radical scavengers; Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
	Isomangiferin 是一种天然产物，具有抗病毒的作用。它还具有抗氧化和自由基清除活性。
TN1274	4-Allylcatechol 2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol	Others	Others
	4-Allylcatechol (Hydroxychavicol) 是合成黄樟素的一种中间体。
T2S1434	Bergaptol 5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-羟基-6,7-呋喃并香豆素,5-Hydroxypsoralen	P450	Metabolism
	Bergaptol (4-Hydroxybergapten) 是CYP3A4酶脱苄基作用的抑制剂(IC50:24.92 uM)，具有抗癌、抗增殖作用。
T39887	(S)-3-(4-Hydroxyphenyl)lactic acid (S)-3-(4-羟苯基)乳酸,(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid	Others; Antioxidant	Others; oxidation-reduction
	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid 是分离自间肠隐球菌培养基的代谢物，具有高的 DPPH 清除自由基活性和抗氧化活性。
T3778	3'-Hydroxypuerarin Pueraria glycoside,3'-hydroxy Puerarin,3'-羟基葛根素	Others; Antioxidant	Others; oxidation-reduction
	Pueraria glycoside 是一种异黄酮，从Pueraria lobata(Willd.) Ohwi 根部分离出来得到。它是抗氧化剂，具有显著的 ONOO(-)，NO•，总 ROS 清除活性。
TN1490	Chrysoeriol	ERK; p38 MAPK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Chrysoeriol 是一种天然黄酮，可从热带植物Coronopus didymus 中提取获得，具有强大的抗氧化功能，能够抑制脂质的过氧化。
T8087	Tropolone	Tyrosinase	Proteases/Proteasome
	Tropolone 是一种 mushroom tyrosinase 抑制剂，IC50=0.4 μM，它的抑制作用可以通过透析或过量的 CU2+逆转。它是 2 位上带有羟基的 tropone 衍生物，是许多 Azulene 衍生物的前体，如 2-methylazulene-1-carboxylate。
T6S1930	Schisanhenol 五味子酚,Schizanhenol,Gomisin-K3	Antioxidant	oxidation-reduction
	Schisanhenol (Schizanhenol) 是一种UGT2B7的抑制剂，是一种天然化合物。
T2S1086	Nepitrin 假荆芥属苷,Nepetin-7-glucoside	Antioxidant	oxidation-reduction
	Nepitrin (Nepetin-7-glucoside) 分离自Scrophularia striata 中，具有强大的抗炎、抗关节炎作用。
TN1644	Flavanomarein	Others	Others
	Flavanomarein 是Coreopsis tinctoria Nutt 的主要黄酮类化合物，对糖尿病性肾病具有保护作用。它具有很好的抗氧化，降糖，降压和降血脂作用。
TN1788	Isookanin	Amylase	Metabolism
	Isookanin 在多种疾病领域有研究价值，包括肿瘤，皮疹，蛇和昆虫叮咬，糖尿病，腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
TN1816	Kadsurin	Antioxidant	oxidation-reduction
	Kadsurin 是一种提取自异形南五味子茎中的天然产物，能够显著降低小鼠肝脏中CCL4诱导的脂质过氧化产物（例如TBA-RS、共轭二烯和荧光产物）。
T2759	Loganin Loganoside,马钱子苷	Apoptosis; NF-κB; BACE; AChR; AChE	Apoptosis; Neuroscience; NF-κB
	Loganin (Loganoside) 是山茱萸中的主要环烯醚萜苷类天然产物，具有抗炎、抗休克的作用。
TN6489	Regaloside A	Others	Others
	Regaloside A 是一种从百合中提取出的苯丙烷，在 160 ppm 时显示出 DPPH 自由基清除活性。Regaloside A 具有抗炎活性和抗抑郁活性。
T5S0089	Kaempferol-3-O-glucorhamnoside Kaempferol 3-glucorhamnoside,百蕊草素I	Antioxidant; p38 MAPK; NF-κB	MAPK; NF-κB; oxidation-reduction
	Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside) 是来源于百蕊草的一种类黄酮，在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T3383	Cimifugin 升麻素,Cimitin	Others	Others
	Cimifugin (Cimitin) 是中草药Saposhnikovia divaricate 的一种生物活性成分。它能够调节紧密连接减少上皮衍生的主动关键因子，对过敏性炎症产生抑制作用。
TN2031	γ-Terpinene Moslene,p-Mentha-1,4-diene,Crithmene	Antioxidant	oxidation-reduction
	γ-Terpinene (p-Mentha-1,4-diene) 是一种单萜化合物，具有高抗氧化属性，适合口服。它展示了直接的自由基清除能力，并且已知是一种有效的抗痛剂。
T1716	Echinacoside	Reactive Oxygen Species; Wnt/beta-catenin	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
	Echinacoside 是一种从Cistanche salsa 中分离的苯乙醇类化合物，抑制Wnt/β-catenin 信号通路。它能够激活 Trk 受体及其下游信号通路而起到神经保护作用，还具有显著的抗骨质疏松作用。
TN1873	Lirinidine	Others; Antioxidant	Others; oxidation-reduction
	Lirinidine 是一种分离自L. tulipifera叶片生物碱，具有抗氧化 (antioxidant) 和抗癌作用。它在体外表现出中等的铁还原能力和较小的自由基清除能力，可用于研究化妆品。
TJS2190	Nordihydroguaiaretic acid 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid	Antioxidant; Ferroptosis; Lipoxygenase; Autophagy	Apoptosis; Autophagy; Metabolism; oxidation-reduction
	Nordihydroguaiaretic acid (NDGA) 是从极叉开拉瑞阿提取出的一种天然产物，是脂氧合酶抑制剂，具有抗氧化和清除自由基的特性。
T0562	Protocatechuic acid 3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid	Others	Others
	Protocatechuic acid (3, 4-Dihydroxybenzoic acid) 是天然的多酚类物质，具有神经保护活性。
T2996	Tetrandrine NSC-77037,d-Tetrandrine,Hanfangchin A,粉防己碱,Fanchinine,Sinomenine A,汉防己甲素	Potassium Channel; Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Tetrandrine (Sinomenine A) 是来自粉防己的一种双苯基异喹啉生物碱，可抑制电压门控钙离子通道 (ICa) 和 Ca2+激活的钾离子通道。
TN1420	Bacopaside I	Others	Others
	Bacopaside I 是一种皂苷，分离自 Bacopa monniera 中，具有抗氧化活性和清除自由基的功能，有抗抑郁作用。
TN1601	Effusol 灯心草菲酚,厄弗酚	Caspase	Apoptosis; Proteases/Proteasome
	Effusol 是一种从 Juncus effuses 中分离到的酚类物质，对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP，保护海马功能对抗应激诱导的认知能力下降。
TN1742	Homovanillyl alcohol 高香草醇,4-羟基-3-甲氧基苯乙醇	TNF; Drug Metabolite	Apoptosis; Metabolism
	Homovanillyl alcohol 是羟基酪醇的生物代谢物。Hydroxytyrosol 是存在于原始橄榄油和葡萄酒中的酚类化合物。它能够保护红细胞免受氧化损伤，并对心血管具有保护作用。
TN3972	Epimedokoreanin B	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Epimedokoreanin B （EKB）是一种从韩国淫羊藿中分离出的异戊烯化类黄酮，在人非小细胞肺癌（NSCLC）A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性，可有清除 DPPH 自由基的活性，能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -（羧甲基）赖氨酸（CML）和 N (Ï) -（羧甲基）精氨酸（CMA）的形成，可通过抑制高级糖化终产物（AGEs）预防糖尿病的临床并发症。
T7984	2-Hydroxyflavanone	Others	Others
	2-Hydroxyflavanone 是一种天然存在的黄酮类化合物，存在于许多植物和水果中。它具有抗氧化、抗炎和抗肿瘤的活性，可以清除自由基，减少炎症，并抑制肿瘤细胞的生长，还具有治疗糖尿病、肥胖症、心血管疾病和神经系统疾病等多种疾病的潜力。
T0926	Azelaic acid Finacea,Azelex,壬二酸,Nonanedioic acid,Anchoic acid	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Azelaic acid (Anchoic acid) 是头发和皮肤调理剂的组分，可由油酸臭氧分解产生。Azelaic acid 通过抑制微生物细胞原蛋白合成对痤疮丙酸杆菌和表皮葡萄球菌具有抑菌活性。Azelaic acid 还具有抑制色素沉着的功能，这是由于其清除自由基作用。
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天然产物

Cat.No: T9057

Target: IL Receptor, TNF, Reactive Oxygen Species

Cat.No: T6S1440

Synonym: 马钱苷酸,Loganate

Target: Others

Cat.No: T9135

Target: Others

Thonningianin A

Cat.No: T3S0218

Target: Apoptosis, Others

Cat.No: T2S1181

Synonym: Aloenin A,Aloearbonaside,芦荟宁

Target: Beta-Secretase, AChR

Cat.No: T22308

Synonym: 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one,丁布

Target: Others, Antibacterial, Antibiotic, Antifungal

3-demethylcolchicine

Cat.No: TN6706

Synonym: 3-去甲秋水仙碱,3-去甲基秋水仙碱

Target: Reactive Oxygen Species

Cat.No: T5728

Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Apoptosis, Reactive Oxygen Species

Rubrofusarin gentiobioside

Cat.No: TN2165

Synonym: Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷

Target: ERK, NF-κB, TGF-beta/Smad

5-Hydroxyoxindole

Cat.No: T37710

Target: Reactive Oxygen Species

Polyporusterone B

Cat.No: TN6909

Synonym: 猪苓酮B,(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one

Target: Others

3'-Methoxypuerarin

Cat.No: T4S2084

Synonym: 3'-甲氧基葛根素,3’- Methoxy Puerarin

Target: Antioxidant

Cat.No: T5S0281

Target: NOS

Cat.No: T7781

Synonym: Reinutrin,Quercetin-3-D-xyloside,槲皮素-3-D-木糖甙

Target: Reactive Oxygen Species

Cat.No: T2936

Synonym: 3,4,5-trimethoxyphenol,3,4,5-三甲氧基苯酚

Target: Others

Cat.No: TN1916

Synonym: 罗汉松树脂酚

Target: ATPase, p38 MAPK, ROS

Cat.No: TN2008

Target: NF-κB, TLR

(+)-Gallocatechin

Cat.No: T3845

Synonym: Gallocatechol,没食子儿茶素没食子酸酯,D-Gallocatechin

Target: Others

Isobutylshikonin

Cat.No: TN1137

Target: Others

(-)-Gallocatechin

Cat.No: T3828

Synonym: (2S,3R)-gallocatechin,(−)-GC,(-)-棓儿茶酸；没食子儿茶素,没食子儿茶素

Target: Others

Cat.No: TN1002

Target: ROS

Cat.No: TN1513

Synonym: 碟豆宁,碟豆素

Target: PKC, Antifection

Cat.No: T3905

Target: Free radical scavengers, Antiviral, Influenza Virus

4-Allylcatechol

Cat.No: TN1274

Synonym: 2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol

Target: Others

Cat.No: T2S1434

Synonym: 5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-羟基-6,7-呋喃并香豆素,5-Hydroxypsoralen

Target: P450

(S)-3-(4-Hydroxyphenyl)lactic acid

Cat.No: T39887

Synonym: (S)-3-(4-羟苯基)乳酸,(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

Target: Others, Antioxidant

3'-Hydroxypuerarin

Cat.No: T3778

Synonym: Pueraria glycoside,3'-hydroxy Puerarin,3'-羟基葛根素

Target: Others, Antioxidant

Cat.No: TN1490

Target: ERK, p38 MAPK, Akt

Cat.No: T8087

Target: Tyrosinase

Cat.No: T6S1930

Synonym: 五味子酚,Schizanhenol,Gomisin-K3

Target: Antioxidant

Cat.No: T2S1086

Synonym: 假荆芥属苷,Nepetin-7-glucoside

Target: Antioxidant

Cat.No: TN1644

Target: Others

Cat.No: TN1788

Target: Amylase

Cat.No: TN1816

Target: Antioxidant

Cat.No: T2759

Synonym: Loganoside,马钱子苷

Target: Apoptosis, NF-κB, BACE, AChR, AChE

Cat.No: TN6489

Target: Others

Kaempferol-3-O-glucorhamnoside

Cat.No: T5S0089

Synonym: Kaempferol 3-glucorhamnoside,百蕊草素I

Target: Antioxidant, p38 MAPK, NF-κB

Cat.No: T3383

Synonym: 升麻素,Cimitin

Target: Others

Cat.No: TN2031

Synonym: Moslene,p-Mentha-1,4-diene,Crithmene

Target: Antioxidant

Cat.No: T1716

Target: Reactive Oxygen Species, Wnt/beta-catenin

Cat.No: TN1873

Target: Others, Antioxidant

Nordihydroguaiaretic acid

Cat.No: TJS2190

Synonym: 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid

Target: Antioxidant, Ferroptosis, Lipoxygenase, Autophagy

Protocatechuic acid

Cat.No: T0562

Synonym: 3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid

Target: Others

Cat.No: T2996

Synonym: NSC-77037,d-Tetrandrine,Hanfangchin A,粉防己碱,Fanchinine,Sinomenine A,汉防己甲素

Target: Potassium Channel, Calcium Channel

Cat.No: TN1420

Target: Others

Cat.No: TN1601

Synonym: 灯心草菲酚,厄弗酚

Target: Caspase

Homovanillyl alcohol

Cat.No: TN1742

Synonym: 高香草醇,4-羟基-3-甲氧基苯乙醇

Target: TNF, Drug Metabolite

Epimedokoreanin B

Cat.No: TN3972

Target: Apoptosis, Others, Antibacterial

2-Hydroxyflavanone

Cat.No: T7984

Target: Others

Cat.No: T0926

Synonym: Finacea,Azelex,壬二酸,Nonanedioic acid,Anchoic acid

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02972	VDB Protein, Mouse, Recombinant (E. coli, His) Vitamin D-binding protein,Gc,Gc-globulin,Group-specific comp...	Mouse	E. coli
	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.4 kDa and the accession number is P21614.
TMPH-02973	VDB Protein, Mouse, Recombinant (His) Vitamin D-binding protein,Gc,Gc-globulin,Group-specific comp...	Mouse	P. pastoris (Yeast)
	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.9 kDa and the accession number is P21614.
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His) Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell.
TMPJ-00753	Myoglobin Protein, Human, Recombinant (His) MGC13548,PVALB,MB,Myoglobin	Human	E. coli
	Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as well as scavenging of NO and reactive oxygen species. MB serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Myoglobin also serves as a sensitive marker for muscle injury resulting from cardiac infarction. Surprisingly, mice in which myogl...
TMPY-01679	LCN1 Protein, Human, Recombinant (His) TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA	Human	HEK293 Cells
	Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo...

重组蛋白

VDB Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02972

Species: Mouse

Expression System: E. coli

VDB Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02973

Species: Mouse

Expression System: P. pastoris (Yeast)

Cytoglobin/CYGB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01248

Species: Human

Expression System: E. coli

Myoglobin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00753

Species: Human

Expression System: E. coli

LCN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01679

Species: Human

Expression System: HEK293 Cells

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