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TMPH-03516
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NPTase Protein, S. aureus, Recombinant (His & SUMO)
30 kDa neutral phosphatase
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Staphylococcus aureus
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E. coli
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|
Highly cationic enzyme that can bind human or rat immunoglobulins as well as serum albumin, and could therefore be involved in post-infectious sequelae. NPTase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.7 kDa and the accession number is P21222. |
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TMPH-01031
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CAPN2 Protein, Human, Recombinant (His)
Calpain-2 catalytic subunit,Millimolar-calpain,Calpain-2 lar...
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Human
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E. coli
|
|
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82... |
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TMPH-01029
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CAPN1 Protein, Human, Recombinant (His)
CANPL1,CAPN1,Calpain-1 catalytic subunit,Micromolar-calpain,...
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Human
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E. coli
|
|
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. CAPN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.9 kDa and the accession number is P07384. |
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TMPH-03166
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Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elas...
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Pseudomonas aeruginosa
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E. coli
|
|
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756. |
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TMPH-03580
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Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Staphylococcus aureus neutral proteinase,aur,Zinc m...
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Staphylococcus aureus
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E. coli
|
|
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177. |
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TMPH-01030
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CAPN14 Protein, Human, Recombinant (His & Myc)
Calpain-14,Calcium-activated neutral proteinase 14,...
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Human
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Baculovirus Insect Cells
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|
Calcium-regulated non-lysosomal thiol-protease. CAPN14 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 78.6 kDa and the accession number is A8MX76. |
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TMPH-01032
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Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO)
Calponin-2,Calponin H2, smooth muscle,Neutral calpo...
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Human
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E. coli
|
|
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q99439. |
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TMPH-03119
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SERPINB1 Protein, Pig, Recombinant (His & Myc)
Leukocyte elastase inhibitor,Serpin B1,Leukocyte neutral...
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Sus scrofa (Pig)
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E. coli
|
|
SERPINB1 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.0 kDa and the accession number is P80229. |
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TMPH-00672
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Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)
stcE,Neutral zinc metalloprotease StcE,Metalloprote...
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E. coli
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E. coli
|
|
Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves human C1 inhibitor (SERPING1), a regulator of multiple inflammatory pathways, and binds and localizes it to bacterial and host cell surfaces, protecting them from complement-mediated lysis. Therefore, the current model proposes two roles for StcE during infection: it acts first as... |
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TMPH-01771
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ASAH2 Protein, Human, Recombinant (His)
HNAC1,LCDase (hCD),BCDase,Non-lysosomal ceramidase,Neutr...
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Human
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E. coli
|
|
ASAH2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9NR71. |
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TMPH-01985
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ASAH2B Protein, Human, Recombinant (His)
ASAH2L,ASAH2B,Putative inactive non-lysosomal ceramidase B,A...
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Human
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E. coli
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|
N/A. ASAH2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C7U1. |
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TMPH-02557
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CAPN1 Protein, Mouse, Recombinant (His)
CANP 1,Calpain-1 catalytic subunit,muCANP,CANPL1,Calcium-act...
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Mouse
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E. coli
|
|
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His-410'. |
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TMPH-01604
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SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)
SLC7A5,y+ system cationic amino acid transporter,Large n...
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Human
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E. coli
|
|
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 19.7 kDa and the accession number is Q01650. |
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TMPY-00963
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ASAH2 Protein, Mouse, Recombinant (His)
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) ...
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Mouse
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HEK293 Cells
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ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 po... |
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TMPH-03396
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TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO)
Mast cell protease 7,Tryptase, skin,Tpsab1,Tryptase alpha/be...
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Rat
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E. coli
|
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Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.4 kDa and the accession number is P27435. |
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TMPH-00627
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GAD-alpha Protein, E. coli, Recombinant (His)
Glutamate decarboxylase alpha,gadA
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E. coli
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E. coli
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|
Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria. |
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TMPK-01303
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TPSAB1 protein, Cynomolgus, Recombinant (His)
Tryptase alpha/beta-1,TPSB1,Tryptase I,TPS2,TPS1,Tryptase al...
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Cynomolgus
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E. coli
|
|
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |
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TMPH-02528
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SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar)
Slc7a10,Solute carrier family 7 member 10,Asc-type amino aci...
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Mouse
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P. pastoris (Yeast)
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Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-His tag. The predicted molecular weight is 22.5 kDa and the accession number is P63115. |
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TMPH-02258
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TPSB2 Protein, Human, Recombinant (E. coli, His)
Tryptase II,TPSB2,Tryptase beta-2
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Human
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E. coli
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Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.4 kDa and the accession number is P20231. |
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TMPH-02957
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TPSAB1 Protein, Mouse, Recombinant (His)
Tryptase,Tryptase alpha/beta-1,Mast cell protease 7,Tpsab1
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Mouse
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E. coli
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Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSAB1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.1 kDa and the accession number is Q02844. |
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TMPH-02257
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TPSB2 Protein, Human, Recombinant (His & Myc)
Tryptase beta-2,TPSB2,Tryptase II
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Human
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P. pastoris (Yeast)
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Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (His & Myc) is expressed in yeast with C-6xHis-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is P20231. |
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TMPH-03569
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IcaB Protein, S. aureus, Recombinant (His & Myc)
Intercellular adhesion protein B,Poly-beta-1,6-N-acetyl-D-gl...
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Staphylococcus aureus
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E. coli
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|
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions. IcaB Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular ... |
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TMPJ-00897
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TPSB2 Protein, Mouse, Recombinant (His)
Tryptase-2,Mast cell protease 6,Tryptase beta-2,Tryptase β-2...
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Mouse
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HEK293 Cells
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Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It plays a role in innate immunity. Tpsb2 can be detected primarily in skin during embryogenesis. Tpsb2 can not be detected at early embryonic stages but is abundantly expressed in later stages with a peak at E17.5-E18.5. Tryp... |
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TMPK-00150
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FOLR1 Protein, Human, Recombinant (His & Avi)
Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a...
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Human
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HEK293 Cells
|
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Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t... |
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TMPJ-00964
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PRCP Protein, Human, Recombinant (His)
PCP,Proline Carboxypeptidase,PRCP,Lysosomal Pro-X Carboxypep...
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Human
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HEK293 Cells
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Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been s... |
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TMPY-01865
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BLMH Protein, Mouse, Recombinant (His)
Bh,bleomycin hydrolase,Bmh,AI035728
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Mouse
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E. coli
|
|
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide antica... |
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TMPY-03439
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UBASH3A Protein, Human, Recombinant (aa 354-623, His)
TULA,STS-2,CLIP4,ubiquitin associated and SH3 domain contain...
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Human
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E. coli
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UBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A gene results in multiple transcript variants. It interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. UBASH3A pro... |
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TMPJ-00136
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MBL2 Protein, Human, Recombinant (His)
Collectin-1,Mannose-Binding Lectin,COLEC1,Mannan-Binding Pro...
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Human
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HEK293 Cells
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Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These h... |
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TMPY-01879
|
S100A14 Protein, Human, Recombinant (His)
S100 calcium binding protein A14,BCMP84,S100A15
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Human
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E. coli
|
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S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of in... |
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TMPY-00818
|
Granzyme H/GZMH Protein, Human, Recombinant (His)
CTSGL2,CSP-C,CCP-X,granzyme H,CTLA1,CGL-2,GZMH
|
Human
|
HEK293 Cells
|
|
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes (A-G and M) have been identified in the mouse, but only five are known in humans (A, B, H, M, and granzyme 3), and granzyme H appears to be specifically human. Human granzyme H is a neutral serine protease that is expressed predominantly in the lymphokine-activated killer (LAK)/... |
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TMPJ-00378
|
Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)
p90,TfR,T9,Trfr,Transferrin receptor protein 1,TR
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Human
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HEK293 Cells
|
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Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o... |
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TMPY-01466
|
S100A12 Protein, Human, Recombinant
MRP6,MRP-6,S100A12,S100 calcium binding protein A12,CAGC,p6,...
|
Human
|
E. coli
|
|
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i... |
|
TMPY-01926
|
S100A10 Protein, Human, Recombinant (His)
ANX2L,S100 calcium binding protein A10,p10,CLP11,MGC111133,G...
|
Human
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E. coli
|
|
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of int... |
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