44
9
13
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4512 |
Magnesium glycinate
magnesium 2-aminoacetate,Magnesium diglycinate,甘氨酸镁 |
Others | Others |
Magnesium glycinate (magnesium 2-aminoacetate) 是一种营养补充剂,是甘氨酸的镁盐,具有良好的理化性质和生物活性。Magnesium 是人体必需的矿物质,参与能量代谢过程,协助维持正常的肌肉功能,对人体起着至关重要的作用。 | |||
T2686 |
Esomeprazole Magnesium
(S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium |
ATPase; Proton pump | Membrane transporter/Ion channel |
Esomeprazole Magnesium (NEXIUM) 是一种口服有效的 H+, K+-ATPase 抑制剂,在上消化道疾病和胃食管反流疾病中具有研究价值。Esomeprazole magnesium 是一种外泌体抑制剂,通过抑制 V-H+-ATPases 来阻断外泌体的释放。 | |||
T40864 |
Magnesium sulfate
|
Others | Others |
Magnesium sulfate 是目前预防和控制子痫发作的抗惊厥剂。Magnesium sulfate 也被广泛用作宫缩剂。 | |||
T8386 |
Esomeprazole Magnesium trihydrate
埃索美拉唑镁三水合物,埃索美拉唑镁(三水),(S)-Omeprazole magnesium trihydrate |
Proton pump | Membrane transporter/Ion channel |
Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) 是一种口服有效的H+, K+-ATPase 抑制剂,在上消化道疾病和胃食管反流疾病的研究中具有价值。它是一种外泌体抑制剂,通过抑制 V-H+-ATPases 来阻断外泌体的释放。 | |||
T12834 |
Saroglitazar Magnesium
|
Others | Others |
Saroglitazar Magnesium 是一种新型过氧化物酶体增殖物激活受体(PPAR)激动剂,对PPARα (EC50 0.65pM)具有显著的激活活性以及对PPARγ(EC50 3 nM)有中等的激活活性。 | |||
T3272 |
Metamizole magnesium
Metamizolemagnesiumsalt,安乃近镁 |
Antibiotic | Microbiology/Virology |
Metamizole magnesium (Metamizolemagnesiumsalt) 是一种止痛药,可以解痉。 | |||
T19389 |
L-Ascorbic acid 2-phosphate magnesium
2-Phospho-L-ascorbic acid magnesium,维生素C磷酸酯镁,维生素 C 磷酸酯镁 |
Phosphatase; Phosphorylase | Metabolism |
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) 是长效的维生素 C 衍生物,能够以刺激胶原蛋白的表达和形成。它提高成骨细胞分化过程中 hASC 中的碱性磷酸酶特性和 runx2A 的表达。它能够以作为培养基补充人脂肪干细胞的成骨分化。 | |||
T9379 |
L-Threonic acid magnesium salt
|
Others | Others |
L-Threonic acid magnesium salt 可增加老年大鼠和晚期阿尔茨海默病 (AD) 模型小鼠的突触密度和记忆能力。 | |||
T33164 |
Magnesium decanoate
Decanoic acid, magnesium salt,Magnesium caprate,Magnesium di(decanoate) |
Others | Others |
Magnesium decanoate is a biochemical. | |||
T32705 |
Levomefolate magnesium
L-Methylfolate magnesium |
Others | Others |
Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across th | |||
T35376 |
Magnesium chloride
|
Others | Others |
Magnesium chloride 可减少活化的促凝血酶原激酶时间。 | |||
T68250 |
Omeprazole magnesium
|
Others | Others |
Omeprazole magnesium 是口服活性的质子泵(proton pump)抑制剂(PPI),用于抑制胃酸,常用于研究胃酸反流和烧心症相关症状。 | |||
T65281 |
Magnesium acetate tetrahydrate
|
Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology |
Magnesium acetate tetrahydrate 是无水醋酸镁盐的水合形式。Magnesium acetate tetrahydrate 常用来合成其他化合物,可作为电解质补充剂或分子生物学实验中的试剂。 | |||
T71560 |
Atorvastatin magnesium trihydrate
|
Others | Others |
Atorvastatin magnesium trihydrate is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia. | |||
T31363 |
Deferitazole magnesium
FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base |
Others | Others |
Deferitazole magnesium is a potential chelator for iron overload treatment. | |||
T69033 |
Magnesium Oxaloacetate
|
Others | Others |
Magnesium Oxaloacetate is an inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O2. | |||
T68467 |
Atorvastatin magnesium
|
Others | Others |
Atorvastatin magnesium is an HMG-CoA inhibitor. | |||
T75327 |
Magnesium silicate
|
Others | Others |
Magnesium silicate (Activated magnesium silicate) 是由氧化镁 (MgO) 和二氧化硅 (SiO2) 组成的化合物。该化合物在制备抗酸剂和抗溃疡剂中应用,同时也作为除臭剂、脱色剂和抗真菌剂使用。 | |||
T65282 |
Magnesium oxide
|
Others | Others |
Magnesium oxide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65282。 | |||
T64455 |
Magnesium citrate
|
Others | Others |
Magnesium citrate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64455,CAS号为 3344-18-1。 | |||
T60665 |
Magnesium salicylate
|
Others | Others |
Magnesium salicylate 可以暂时缓解轻微疼痛,是一种口服镇痛剂。 | |||
T35319 |
Zy 15109
N-Acetyl-aspartyl magnesium glutamate,Zy15109,Magnesium N-acetyl-aspartylglutamate |
Others | Others |
Zy 15109 can be used as inhaled mast cell stabilizer. | |||
T64541 |
Magnesium sulfate hydrate
|
Others | Others |
Magnesium sulfate hydrate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64541。 | |||
T61467 |
Esomeprazole magnesium salt
|
Others | Others |
Esomeprazole magnesium salt is a potent and orally active proton pump inhibitor that effectively reduces acid secretion in gastric parietal cells by inhibiting the H+, K+-ATPase. This compound has shown promise for the research and treatment of symptomatic gastroesophageal reflux disease [1][2][3]. | |||
T64727 |
Magnesium silicate adsorbent(Synthetic)
|
Others | Others |
Magnesium silicate adsorbent(Synthetic) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64727。 | |||
T7098 |
BAPTA
1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
BAPTA 是非渗透性、选择性的钙离子螯合剂,对 Ca2+的亲和力是 Mg2+的 105 倍。它是一个有价值的研究钙在细胞信号传导中的作用的工具。 | |||
T75325 |
ATP dimagnesium
|
Others | Others |
ATP dimagnesium 是体内能量储存和代谢的重要物质,参与机体的能量循环和代谢能量。ATP dimagnesium 可在细胞中充当辅酶,可被当做一种信号分子。 | |||
T75656 |
Calcimycin hemimagnesium
|
Others | Others |
Calcimycin (A-23187) hemimagnesium,一种具有抗生素功能的独特二价阳离子离子载体(例如钙离子和镁离子),通过提高细胞内钙浓度而诱导Ca2+依赖性细胞死亡。该化合物还能抑制革兰氏阳性细菌和部分真菌生长,同时抑制ATP酶活性并解耦哺乳动物细胞的氧化磷酸化(OXPHOS),触发细胞凋亡(apoptosis)。 | |||
T18934 |
Calmagite
|
Others | Others |
Calmagite 是络合指示剂,可用于多种样品中的钙和镁的检测。 | |||
T28020 |
Mesendogen
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
Mesendogen 是瞬时受体电位阳离子通道、亚家族 M、成员 6 (TRPM6) 和 7 (TRPM7) 的抑制剂,通过抑制 TRPM6/TRPM7 镁通道活性起作用。 | |||
T34639 |
Sigetin
|
Others | Others |
Sigetin affects the transport of calcium and magnesium in uterine smooth muscle and can be used in fetal development. | |||
T19019 |
KMG-104AM
|
Others | Others |
KMG-104AM is a selective fluorescein-derived magnesium fluorescent membrane-permeable probe. It is successfully used to Intracellular 3D Mg2+ Imaging. | |||
T40948 |
KMG-104
|
Others | Others |
KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types. | |||
T83941 |
Mag-Fura-2 AM
|
||
Mag-Fura-2 AM是一种可渗透细胞的荧光镁离子(Mg2+)指示剂,对Mg2+具有高度选择性,相较于其他二价离子(Zn2+、Cu2+和Ca2+)。其对Mg2+的选择性超过13,000倍(Mg2+Kd为1.9 nM,相对于Ca2+Kd的25 μM)。激发和发射峰值(λ)分别为369 nm和511 nm。Mag-Fura-2 AM可作为间接指示ATP消耗/产生的指标。 | |||
T83837 |
Rp-Thymidine-5'-O-(1-thiotriphosphate) sodium
Rp-dTTP-α-S |
Others | Others |
Rp-Thymidine-5'-O-(1-thiotriphosphate) (Rp-TTP-α-S) 是含硫核苷酸衍生物 TTP-α-S 的一个异构体。它能与HIV-1逆转录酶结合(在镁、锰酸盐和钴存在下的Kds分别为45.7、27.32和39.44 µM)。 | |||
T83811 |
2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate sodium
2'(3')-ANT-ATP |
||
2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate(2'-ANT-ATP)与3'-ANT-ATP是荧光ATP衍生物,可自发地进行异构化。在水中,2'(3')-ANT-ATP的激发波长为330 nm时,发射最大波长为428 nm。它对哺乳动物腺苷酸环化酶(AC1)、AC2及AC5显示出抑制作用,抑制常数(Kis)分别为130、640和120 nM。此外,它还能抑制百日咳杆菌腺苷酸环化酶毒素CyaA(在锰和镁存在下,Kis分别为1.3和20 µM)、炭疽杆菌腺苷酸环化酶毒素水肿因子(在锰和镁存在下,Kis分别为0.44和5.15 µM)以及大肠杆菌重组酶A(RecA;Ki = 6.3 µM)。 | |||
T83838 |
Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium
Sp-TTP-α-S |
Others | Others |
Sp-Thymidine-5'-O-(1-thiotriphosphate)(Sp-TTP-α-S)是含硫核苷酸衍生物TTP-α-S的一个异构体。它能够结合HIV-1逆转录酶(在镁、锰酸盐和钴存在时,Kds分别为2.88、4.23和20.21 µM)。Sp-TTP-α-S抑制脱氧核苷酸三磷酸三磷酸水解酶SAMHD1(Ki为46 nM)。 | |||
T71870 |
CP21
|
Others | Others |
CP21 is an iron chelator that binds to iron in a 3:1 (ligand:iron) ratio. It is active against P. falciparum when used at concentrations of 10 and 100 µM. CP21 inhibits production of prostaglandin I2 induced by epinephrine, arachidonic acid, or A23187 in isolated rat aortic rings with IC50 values of 1.3, 1.3, and 1.4 mM, respectively. It inhibits glutamate-induced oxytosis, as well as decreases iodoacetic acid-induced cytotoxicity in an in vitro model of ischemia, in HT22 mouse hippocampal cells... | |||
T35731 |
Deethylindanomycin
|
Others | Others |
Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg/ml, respectively). It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg/g in the diet. Deethylindanomycin acts as an ionop... | |||
T84995 |
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA
1-Hexadecanoyl-d9-2-hydroxy-sn-glycero-3-phosphate |
Others | Others |
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA (1-palmitoyl-d9LPA) serves as an internal standard for the quantification of 1-palmitoyl LPA using GC- or LC-MS. This compound, an analog of LPA with palmitic acid at the sn-1 position, activates reporter gene expression in PC12 cells fitted with human lysophosphatidic acid receptor 4 (LPA4) at 0.01 to 10 µM concentrations. Additionally, 1-palmitoyl LPA prompts aggregation in isolated human platelets within the 12-300 µM range, a process reversible by pro... | |||
T37762 |
Fura-FF AM
|
||
Fura-FF AM is a cell-permeable acetoxymethyl ester of the fluorescence calcium indicator fura-FF (potassium salt) . As fura-FF AM enters cells, it is hydrolyzed by intracellular esterases to produce fura-FF. Fura-FF is a difluorinated derivative of the calcium indicator fura-2 . Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation. Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively). ... | |||
T35687 |
Collismycin A
|
Others | Others |
Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria (MICs = 6.25 and 100 μg/ml) and fungi (MICs = 12.5-100 μg/ml). It inhibits proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells (IC50s = 0.3, 0.6, and 0.3 μM, respectively) and NIH373 fibroblasts (IC50 = 56.6 μM) but not MDA-MD-231 breast canc... | |||
T83843 |
2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium
2'(3')-ANT-GTP |
||
2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate(2'-ANT-GTP)及3'-ANT-GTP是荧光GTP衍生物,能够自发进行异构化。2'(3')-ANT-GTP在水中的激发波长为330 nm时,发射最大波长为428 nm。它抑制哺乳动物腺苷酸环化酶1(AC1;在锰存在下Ki=10 nM)、B. anthracis AC毒素水肿因子(在锰和镁存在下Kis分别为4.1 和 13 µM)及B. pertussis AC毒素CyaA(在锰存在下Ki=29 µM)。 | |||
T83820 |
TNP-GTP sodium
TNP-Guanosine 5'-triphosphate |
||
TNP-GTP是一种荧光衍生物,源自蛋白质合成与糖异生的能量底物鸟苷三磷酸(GTP)。其在水中激发波长为410 nm时,发射最大波长为552 nm,而在40%和80%的N,N-二甲基甲酰胺中,其荧光强度增加,发射波长分别向544 nm和532 nm移动,这是因为N,N-二甲基甲酰胺的极性比水小。TNP-GTP是谷氨酸脱氢酶的抑制剂(Ki = 2.7 μM)。当与谷氨酸脱氢酶结合时,TNP-GTP的荧光强度增加,且发射波长从552 nm变为545 nm,此效果可以通过加入GTP来阻断。TNP-GTP还是嘌呤P2X2和P2X2/3受体的拮抗剂(IC50s分别为0.4和1.2 nM)。它还选择性抑制大鼠可溶性鸟苷酸环化酶(sGC; Ki = 11 nM)高于牛肝谷氨酸脱氢酶(GDH; Ki = 2.7 µM)以及钙调素依赖的B. pertussis腺苷酸环化酶(AC)毒素(Kis在存在锰或镁时分别为20和320 µM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20793 |
Magnesium Lithospermate B
丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B |
Others | Others |
Magnesium Lithospermate B 是一种咖啡酸四聚体的衍生物,从Salviae miltiorrhizae 中提取得到。它能够抑制神经炎症并减轻神经变性。它被广泛用于心血管疾病的研究,并且可以防止葡萄糖引起的细胞内氧化损伤。 | |||
T20574 |
Magnesium lactate
Bis(lactato)magnesium |
||
Magnesium lactate is a magnesium donor and buffering agent. | |||
T19281L |
Dihydroxyacetone phosphate hemimagnesium hydrate
DHAP Mg,Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base) |
Others | Others |
Dihydroxyacetone phosphate hemimagnesium salt hydrate 也称为磷酸二羟基丙酮或 3-羟基-2-氧代丙基磷酸。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 存在于从细菌到人类的所有生物中。在人类体内, Dihydroxyacetone phosphate hemimagnesium salt hydrate参与许多酶促反应。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 已被研究用于治疗淋巴瘤、大细胞淋巴瘤、弥漫性淋巴瘤。 | |||
T0792 |
(-)-Sparteine sulfate pentahydrate
(-)-Sparteine Sulfate,Lupinidine sulfate pentahydrate,(-)-Sparteine sulfate salt,sulfate pentahydrate,五水合硫酸司巴丁 |
Sodium Channel | Membrane transporter/Ion channel |
(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) 是一种生物碱,是钠通道抑制剂,属于1a 类抗心律失常药。 | |||
T2803 |
Monocrotaline
野百合碱,Crotaline |
TGF-beta/Smad | Stem Cells |
Monocrotaline (Crotaline) 是一种吡咯里西啶生物碱,从猪屎豆植物的种子中提取得到,可诱导啮齿动物产生肺动脉高血压。 | |||
T7963 |
2,4-Dihydroxypyridine
|
Others | Others |
2,4-Dihydroxypyridine 是一种吡啶衍生物,作为螯合剂与金属离子结合并形成络合物。它被用作测定各种离子浓度的试剂,如钙、镁和磷酸盐;也用于测量酶催化反应的速率;还用于蛋白质、碳水化合物和其他生物分子的检测和定量。 | |||
T10662 |
Calcimycin hemicalcium salt
Antibiotic A-23187 hemicalcium salt,A-23187 hemicalcium salt |
Others | Others |
Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration. | |||
T3029 |
Sparteine sulfate
硫酸司巴丁,Depasan,Tocosimplex,Actospar |
Others; Sodium Channel | Membrane transporter/Ion channel; Others |
Sparteine sulfate (Tocosimplex) 是一种 1a 类抗心律失常药和钠通道阻滞剂。它可以螯合二价钙和镁。 | |||
T82926 |
Bacteriopheophytin
|
||
Bacteriopheophytin是细菌脱镁叶绿素的一种,由细菌叶绿素去除镁中心并由两个氢原子取代形成。在紫色细菌的反应中心(RC)中,它作为电子受体参与电子转移过程。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03857 |
MMGT1 Protein, Human, Recombinant (His)
membrane magnesium transporter 1,TMEM32,EMC5 |
Human | HEK293 Cells |
MMGT1 (Membrane Magnesium Transporter 1, also known as EMC5 and TMEM32) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein belongs to the membrane magnesium transporter (TC 1.A.67) family which is a group of magnesium transporters that are part of the TOG superfamily. It mediates Mg(2+) transport. MMGT1 is described as having 335 amino acids and five TMSs with an N-terminal cleavage site and some phosphorylation sites. It is widely expressed ... | |||
TMPJ-01205 |
MDP1 Protein, Human, Recombinant (His)
Magnesium-dependent phosphatase 1,MDP-1,EC=3.1.3.48 |
Human | HEK293 Cells |
MDP1, which is short for nesium-dependent phosphatase 1, is a 176 aa. protein. It has 3 forms by different alternative splicing. This protein belongs to the HAD-like hydrolase superfamily, and usually takes its function with Magnesium. It can be inhibited by vanadate and zinc, and slightly by calcium. MDP1 is a Magnesium-dependent phosphatase which may act as a tyrosine phosphatase. | |||
TMPK-00742 |
PRL-3/PTP4A3 Protein, Human, Recombinant (His)
PRL-R,PRLR,PRL3,PTP4A3,PRL-3 |
Human | E. coli |
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) plays an important role in the tumorigenesis and metastasis of multiple tumors. | |||
TMPK-01132 |
PRL-1/PTP4A1 Protein, Human, Recombinant (His)
PTPCAAX1,PRL1,PRL-1,PTP(CAAXI),PTP4A1 |
Human | E. coli |
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is a key molecule that activates tyrosine phosphorylation, which is important for cancer progression and metastasis. | |||
TMPH-00726 |
Ribokinase Protein, E. coli, Recombinant (His)
Ribokinase,rbsK |
E. coli | E. coli |
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | |||
TMPH-01394 |
GRIN1 Protein, Human, Recombinant (His)
N-methyl-D-aspartate receptor subunit NR1,Glutamate [NMDA] r... |
Human | E. coli |
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. GRIN1 Protein, Human, Recombinant (His)... | |||
TMPJ-01057 |
PSP Protein, Human, Recombinant (His)
PSPH,L-3-Phosphoserine Phosphatase,PSPase,Phosphoserine Phos... |
Human | E. coli |
Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial fea... | |||
TMPH-00743 |
PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)
Transcriptional regulatory protein PhoP,phoP |
E. coli | HEK293 Cells |
Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG. Mediates magnesium influx to the cytosol by activation o... | |||
TMPJ-00660 |
IMPase2 Protein, Human, Recombinant (His)
Inositol-1(or 4)-Monophosphatase 2,IMPA2,IMP 2,IMPase 2,Inos... |
Human | E. coli |
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphat... | |||
TMPJ-00926 |
GCA Protein, Human, Recombinant (GST)
GCA,Grancalcin,GCL |
Human | E. coli |
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and ... | |||
TMPJ-00905 |
DTYMK Protein, Human, Recombinant (His)
DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TYMK |
Human | HEK293 Cells |
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ... | |||
TMPY-02197 |
PPM1G Protein, Human, Recombinant (aa 317-546, His)
protein phosphatase, Mg2+/Mn2+ dependent, 1G,PP2Cγ,PPP2CG,PP... |
Human | E. coli |
Protein phosphatase 1G, also known as Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma, PP2C-gamma, PPM1G and PPM1C, is a cytoplasm protein that belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis, skeletal muscle, and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress respons... | |||
TMPY-01819 |
PDE1B Protein, Human, Recombinant (His & GST)
PDES1B,phosphodiesterase 1B, calmodulin-dependent,PDE1B1 |
Human | Baculovirus Insect Cells |
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE1 subfamily. Phosphodiesterase-1A (PDE1A), Phosphodiesterase-1B (PDE1B), Phosphodiesterase-4B (PDE4B), and Phosphodiesterase-4A (PDE4A) are important regulators of signal transduction in striatum due to their catalysis of cyclic AMP and cyclic GMP. PDE1B is highly expressed in the striatum. It b... |