40
5
2
15
Cat. No. | Product Name | ||
---|---|---|---|
L4710 | 非甾体类抗炎化合物库 | 530 compounds | |
530 种非甾体类的抗炎相关化合物,可用于高通量和高内涵筛选; | |||
L1700 | 抗病毒库 | 1040 compounds | |
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38238 |
2'-Deoxy-2'-fluorocytidine
|
Nucleoside Antimetabolite/Analog; Influenza Virus | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
2'-Deoxy-2'-fluorocytidine 是一种核苷类似物,可有效抑制刚果出血热病毒的复制。2'-Deoxy-2'-fluorocytidine 与 T705 的协同作用会增强对CCHFV 复制的抵抗效力。 | |||
T38236 |
2′-Deoxy-2′-fluoroguanosine
|
Nucleoside Antimetabolite/Analog; Influenza Virus | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
2′-Deoxy-2′-fluoroguanosine 是一种核苷类似物,有效抑制流感病毒,抑制A 型和B 型流感病毒的EC90值 <0.35 μM。2′-Deoxy-2′-fluoroguanosine 显著抑制流感病毒在上呼吸道中的复制,从而改善鼻腔炎症和发烧。 | |||
T7596 |
Firocoxib
非罗考昔,ML 1785713 |
COX | Immunology/Inflammation; Neuroscience |
Firocoxib (ML 1785713) 是一种可口服的 COX-2选择性抑制剂,IC50为 0.13 μM。它具有抗炎作用,对 COX-2的选择性比对 COX-1 的选择性高 58 倍,IC50为 7.5 μM。 | |||
T1531 |
Mometasone furoate
糠酸莫美他松,糠酸莫米松,Sch32088 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Mometasone furoate (Sch32088) 是糖皮质激素受体激动剂,具有抗炎和抗过敏作用。它是皮质固醇类试剂,动物模型中,可局部应用于气道炎症、慢性皮肤湿疹、哮喘。 | |||
T0059 |
Diphenylpyraline hydrochloride
盐酸双苯比拉林,4-Diphenylmethoxy-1-methylpiperidine hydrochloride |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) 是一种组胺 H1 受体的拮抗剂,抑制多巴胺的吸收。它是可口服的抗组胺试剂,具有抗胆碱和抗过敏作用,可用于缓解过敏性疾病,如鼻炎、花粉热和瘙痒性皮肤疾病等。 | |||
T21419 |
Diphenhydramine
苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Diphenhydramine (Syntedril) 是第一代具有抗胆碱能作用的H1 受体拮抗剂,它能透过血脑屏障。 | |||
T11281L |
FGI-106 tetrahydrochloride
|
Virus Protease; HCV Protease; Influenza Virus; HIV Protease | Microbiology/Virology; Proteases/Proteasome |
FGI-106 tetrahydrochloride 对多种病毒具有抑制活性,有抗埃博拉病毒,裂谷病毒和登革热病毒的 EC50分别为 100 nM,800 nM 和 400-900 nM,抑制非失血性发热病毒HCV 和HIV-1的EC50分别为 200 nM 和 150 nM 。 | |||
T0005 |
Aspirin
阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA |
Mitophagy; Virus Protease; COX; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Aspirin (Acetylsalicylic Acid) 是一种选择性 COX 抑制剂,具有多种药理活性。它是组蛋白去乙酰化酶抑制剂,可上调细胞周期阻滞蛋白 p21,抑制携带 COX-1 的卵巢 Y 细胞。 它还抑制 HUVEC 和新生大鼠心室心肌细胞中 COX-2 的表达,分别减少 PG 的产生和 ERK 和 NF-KB 的下调。 | |||
T69126 |
Clofeverine (free base)
|
Others | Others |
Clofeverine (free base) is a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was comparable to that of isoproterenol and 100 times higher than that of papaverine. | |||
T69324 |
Clofeverine hydrochloride
|
Others | Others |
Clofeverine hydrochloride is the salt form of Clofeverine (free base), a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was comparable to that of isoproterenol and 100 times higher than that of papaverine. | |||
T9957 |
LASV inhibitor 3.3
|
Virus Protease | Microbiology/Virology |
LASV inhibitor 3.3 是一种针对溶酶体相关膜蛋白 1 (LAMP1) 的拉沙热病毒 (LASV) 抑制剂,LAMP1 是一种在感染期间与 LASV 糖蛋白 (GP) 结合的宿主因子。 | |||
T13161 |
Tin-protoporphyrin IX dichloride
SnPPIX,SnPPIX dichloride |
Virus Protease; Autophagy | Autophagy; Microbiology/Virology |
Tin-protoporphyrin IX dichloride (SnPPIX dichloride) 是血红素加氧酶-1 (HO-1) 抑制剂,具有抗病毒活性,抑制登革热和黄热病病毒,可改善肝部分切除术后的肝脏再生。 | |||
T1553 |
Chlorpheniramine maleate
马来酸氯苯那敏,NCI-C55265,Chlorphenamine maleate |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Chlorpheniramine maleate (NCI-C55265) 是一种组胺 H1 拮抗剂,IC50为12 nM,用于过敏反应、花粉热、鼻炎、荨麻疹和哮喘。 | |||
T83975 |
Fenclozine Maleate
S 1429 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Fenclozine Maleate (S 1429) 是一种潜在的组胺H1受体拮抗剂 ,可用于研究发热、炎症和疼痛。 | |||
T4563 |
Thonzylamine
neohetramine,松齐拉敏 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂,具有抗组胺和抗过敏特性,可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。 | |||
T0785 |
Dexchlorpheniramine Maleate
S-(+)-Chlorpheniramine maleate salt,右泛醇,马来酸右氯苯那敏 |
Dopamine Receptor; 5-HT Receptor; Norepinephrine; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) 是一种具有抗胆碱能特性的抗组胺药,用于治疗花粉热或荨麻疹等过敏性疾病。 | |||
T0118 |
Mizolastine
SL 850324,咪唑司汀,咪唑斯汀 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Mizolastine (SL 850324) 是组胺 H1 受体拮抗剂,IC50为 47 nM。它用于治疗过敏反应,如花粉热和荨麻疹等。 | |||
T21390 |
Fexofenadine
Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Fexofenadine (Carboxyterfenadine) 是一种抗组胺药物,用于治疗过敏症状,如鼻塞、花粉热和荨麻疹。与第一代抗组胺药相比,它通过血脑屏障并引起镇静的能力较差。 | |||
T1002 |
Etodolac
Ultradol,AY-24236,依托度酸,Etodolic acid,Lodine |
Retinoid Receptor; COX | Immunology/Inflammation; Metabolism; Neuroscience |
Etodolac (AY-24236) 是一种吡喃羧酸和非甾体抗炎药,具有解热和镇痛活性,对 COX 的 IC50为53.5 nM。 | |||
T21369 |
Mecillinam
Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX |
Antibacterial | Microbiology/Virology |
Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。 | |||
T0322 |
Fipexide
|
Dopamine Receptor; AChR | GPCR/G Protein; Neuroscience |
Fipexide 是对氯苯乙酸衍生物,是哌嗪化学类的精神活性药物,作为促智药物,有用于老年痴呆的研究潜力。它可降低了纹状体腺苷酸环化酶的活性,通过多巴胺能神经传递对认知表现出积极的作用。 | |||
T11281 |
FGI-106
|
Others | Others |
FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. Furthermore, it effectively inhibits non-hemorrhagic fever viruses such as HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively. | |||
T24077 |
G202-0362
|
Others | Others |
G202-0362 is an antiviral agent against Rift Valley fever virus. It acts by blocking virus budding from the trans Golgi. | |||
T15554 | IHVR-19029 | Others | Others |
IHVR-19029 is an effective endoplasmic reticulum (ER) α-glucosidases I and II inhibitor (IC50: 0.48 μM for ER a-glucosidase I). IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as Ebola virus, Dengue virus, and Rift | |||
T21247 |
Carbinoxamine
Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine |
Others | Others |
Carbinoxamine, an anticholinergic and antihistamine agent, is used for hay fever, angioedema, vasomotor rhinitis, mild urticaria, dermatographism and allergic conjunctivitis. It is a histamine antagonist, specifically an H1-antagonist. | |||
T27590 |
IHVR-11029
IHVR 11029 |
Others | Others |
IHVR-11029 is a potent inhibitor of ER α-glucosidase. IHVR-11029 is active against multiple hemorrhagic fever viruses and efficiently disrupts the morphogenesis of a broad spectrum of enveloped viruses. | |||
T27050 |
CM-10-18
CM-1018 |
Others | Others |
CM-10-18 is a potent inhibitor of ER α-glucosidase. CM-10-18 demonstrated superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever. CM-10-18 efficiently protected the lethality of dengue virus | |||
T31396 |
Dexbrompheniramine maleate
D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral |
Others | Others |
Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the gastrointestinal tract, blood vessel | |||
T22983 |
Mizolastine dihydrochloride
|
Others | Others |
Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM). It also used in the treatment of hay fever, hives, and other allergic reactions. | |||
T69474 |
Naproxen ethyl ester
|
Others | Others |
Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor. | |||
T70855 |
Favipiravir sodium
|
Others | Others |
Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. | |||
T38957 |
2'-Deoxy-5'-O-DMT-2'-fluorouridine
|
Others | Others |
2'-Deoxy-5'-O-DMT-2'-fluorouridine is a nucleoside analogue compound derived from 5'-O-DMTr-5-FUDR. This compound exhibits strong anti-yellow fever (YFV) activity. | |||
T37870 |
Bz-Nle-Lys-Arg-Arg-AMC
|
Others | Others |
Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used NS3 substrate (kcat = 2.9 s 1, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s 1, the Km value 14.6 μM. | |||
T75276 |
Dexbrompheniramine
|
Others | Others |
Dexbrompheniramine为口服活性H1受体拮抗剂(H1 receptor),具有抗组胺药属性,能够减轻天然化学组胺的作用。该化合物适用于花粉热与荨麻疹的研究。 | |||
T69267 |
Naproxen glucuronide
|
Others | Others |
Naproxen glucuronide is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a nonselective COX inhibitor. | |||
T69491 |
(E/Z)-Ensifentrine
|
Others | Others |
(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effects. It is being developed by Verona Pharma as a potential treatment for asthma and hay fever, and is currently in clinical trials. | |||
T70954 |
SP-187 HCl
|
Others | Others |
SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium. | |||
T81309 |
RCB16007
|
Others | Others |
RCB16007为一种抗黄热病毒(YFV)化合物,对西尼罗河病毒显示出抑制活性,具体抑制浓度为EC50: 7.9 μM,细胞毒性浓度为CC50: 17 μM。 | |||
T83121 |
Anatumomab mafenatox
ABR-214936 |
||
Anatumomab mafenatox (ABR-214936)是一种73 KDa的重组蛋白,针对广泛表达于恶性肿瘤中的肿瘤相关抗原5T4。该分子构建于修饰后的SEA和小鼠Fab片段之间。Anatumomab mafenatox的主要副作用包括发烧、低血压、疼痛、恶心和嗜睡。 | |||
T36829 |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 |
Others | Others |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimes... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3328 |
Angelic Acid
2-Methylisocrotonic acid,(Z)-2-Methylbut-2-enoic acid,当归酸,cis-2-Methyl-2-butenoic acid |
Others | Others |
Angelic Acid ((Z)-2-Methylbut-2-enoic acid) 是一种存在于Anthemis nobilis 精油中的酯,能够促进伤口愈合,具有促进安定和精神药物的作用。 | |||
T20648 |
Dodecyl gallate
没食子酸月桂酯,NSC-133463,Nipagallin LA,Lauryl gallate,Progallin LA,NSC 133463,NSC133463 |
Others; Antioxidant; Antiviral | Immunology/Inflammation; Others; oxidation-reduction |
Dodecyl gallate 是一种抗氧化剂,普遍用作食品制造及制药和化妆品行业中。它还对动物病毒,如非洲猪瘟病毒 (ASFV)具有作用活性。 | |||
T25457 |
Glyceryl monolinoleate
Emalsy MU,Linolein, mono-,Sunsoft 8090,Rikemal MU 100 |
||
Glyceryl monolinoleate can inactivate or inhibit African Swine Fever virus. | |||
T10959 |
Daphnin
|
Others | Others |
Daphnin is one of the main coumarin bioactive ingredients with antibacterial activity. Daphnine is isolated from the entire Daphne fragrance, which is a folk medicine used in China to relieve fever. | |||
T25789 |
Melianone
NSC 302037,NSC-302037,NSC302037 |
||
Melianone exhibits antiviral activity (EC50s: 3-11μM) against three important human pathogens, belonging to the Flaviviridae family, West Nile virus, Dengue virus, and Yellow Fever virus. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03594 |
Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO)
SPE A,Scarlet fever toxin,Exotoxin type A,speA,Eryt... |
Streptococcus pyogenes | E. coli |
Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever. Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.6 kDa and the accession number is P0DJY7. | |||
TMPH-00402 |
Classical swine fever virus Genome polyprotein (His)
Genome polyprotein |
CSFV | Baculovirus Insect Cells |
Classical swine fever virus Genome polyprotein (His) is expressed in Baculovirus. | |||
TMPH-03482 |
Sandfly fever sicilian virus (SFS) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
SFSV | E. coli |
Sandfly fever sicilian virus (SFS) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.0 kDa and the accession number is P12793. | |||
TMPY-05194 |
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G2 Protein (His)
|
RVFV | Baculovirus Insect Cells |
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G2 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.1 kDa and the accession number is A2T077. | |||
TMPY-05175 |
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G1 Protein (His)
|
RVFV | Baculovirus Insect Cells |
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is A2T077. | |||
TMPY-00061 |
Rift Valley fever virus (TAN/Dod-002/07) RVFV-L Protein (His)
RVFV-L |
RVFV | E. coli |
Rift Valley fever virus (TAN/Dod-002/07) RVFV-L Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.4 kDa and the accession number is AEB20483.1. | |||
TMPH-03415 |
Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)
Non-structural protein S,NSS |
RVFV | E. coli |
Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest. Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc) is expressed... | |||
TMPH-03416 |
Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO)
N,Nucleoprotein,Nucleocapsid protein |
RVFV | E. coli |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles. Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.... | |||
TMPY-04476 |
MVK Protein, Human, Recombinant (His & GST)
POROK3,LRBP,MVLK,MK,mevalonate kinase |
Human | Baculovirus Insect Cells |
Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in the cholesterol biosynthetic pathway. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia,... | |||
TMPH-03548 |
Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His)
entG,Enterotoxin type G,SEG |
Staphylococcus aureus | P. pastoris (Yeast) |
Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.0 kDa and the accession number is P0A0L7. | |||
TMPH-03547 |
Enterotoxin type G Protein, S. aureus (strain Mu50/ATCC 700699), Recombinant (His & SUMO)
SEG,Enterotoxin type G,entG |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Enterotoxin type G Protein, S. aureus (strain Mu50/ATCC 700699), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P0A0L6. | |||
TMPH-03546 |
Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His & SUMO)
Enterotoxin type G,entG,SEG |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P0A0L7. | |||
TMPY-03445 |
Aspartate Aminotransferase Protein, Human, Recombinant (His)
ASTQTL1,glutamic-oxaloacetic transaminase 1, soluble,cCAT,cA... |
Human | E. coli |
GOT1 (Glutamic-Oxaloacetic Transaminase 1) is a Protein Coding gene. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme that exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. GOT1 is an important regulator of levels of glut... | |||
TMPJ-00280 |
TNF R1 Protein, Mouse, Recombinant
Tnfrsf1a,Tumor necrosis factor receptor superfamily member 1... |
Mouse | E. coli |
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the... | |||
TMPY-02516 |
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
interferon, α10,interferon, alpha 10,IFN-alphaC,MGC119879,干扰... |
Human | HEK293 Cells |
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen... |