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Search Results for " dietary "

Targets Recommended: Others

65

抑制剂 & 化合物

48

天然产物

2

化合物库

17

重组蛋白

8

同位素标记化合物

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Cat. No.	Product Name
L6740	抗结直肠癌中药单体化合物库		382 compounds
	382 种抗结直肠癌相关的中药单体集合，是药物开发、药理研究的有效工具；
L6820	烟草单体化合物库		747 compounds
	747种烟草单体化合物的独特集合，可用于高通量筛选和高内涵筛选

化合物库

抗结直肠癌中药单体化合物库

Cat.No: L6740

Compounds: 382

烟草单体化合物库

Cat.No: L6820

Compounds: 747

Cat. No.	Product Name	Target	Signaling Pathways
T0001	Iron(II) fumarate Ferrous fumarate,Iron Fumarate,富马酸铁 (II),富马酸亚铁	Others	Others
	Iron(II) fumarate (Ferrous fumarate) 是一种口服活性膳食补充剂，是一种富马酸的铁 (II) 盐，可用于研究缺铁性贫血。
T19528	Propionylcarnitine Propionyl carnitine	Others	Others
	Propionylcarnitine (Propionyl carnitine) 是一种被广泛使用的膳食补充剂，有青光眼和难道破裂有关。
T1593	Ezetimibe 依泽替米贝,SCH 58235	Others; Nrf2; NPC1L1; Autophagy	Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others
	Ezetimibe (SCH 58235) 是一种膳食胆固醇吸收抑制剂。它是一种NPC1L1抑制剂，是有效的Nrf2激活剂。
T0490	Chlorpropamide Diabinese,氯磺丙脲	ATPase; ABC	Membrane transporter/Ion channel
	Chlorpropamide (Diabinese) 是口服降糖剂，可用于研究非胰岛素依赖型糖尿病。
T6344	Sevelamer hydrochloride Sevelamer HCl	FXR; Autophagy	Autophagy; Metabolism
	Sevelamer hydrochloride (Sevelamer HCl) 是一种磷酸盐结合药物，用于通过与膳食磷酸盐结合并阻止其吸收来治疗高磷血症。
T7593	Levomefolate calcium 左旋甲状腺素钙,L-5-甲基四氢叶酸钙	Antifolate	Cell Cycle/Checkpoint
	Levomefolate calcium 是一种人工形式的叶酸。它是叶酸的一种辅酶形式，是膳食补充剂中生物利用度更高的替代品。
T22484	(±)-Propionylcarnitine chloride Propionyl-DL-carnitine chloride	Endogenous Metabolite	Metabolism
	(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) 是一种短链酰基肉碱的混合物，可用作膳食补充剂，可用于研究慢性糖尿病。
T1129	Benfotiamine Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺	Others	Others
	Benfotiamine (S-Benzoylthiamine O-monophosphate) 是维生素 B1 的类似物，其吸收率和生物利用度比维生素B1高，具有直接抗氧化能力，可防止DNA 损伤。它常用作糖尿病并发症的食品补充剂。
T20062	Thiamine disulfide 二硫化硫胺,TDS,Daiomin,Algoneurina	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Thiamine disulfide (Algoneurina) 是一种存在于食物中的维生素，可作为膳食补充剂和药物生产。它还充当许多中枢代谢酶的辅助因子。
T20266	Tetrasodium glutamate diacetate Glutamate diacetate tetrasodium,GLDA	Others	Others
	Tetrasodium glutamate diacetate (Glutamate diacetate tetrasodium) 是一种可降解螯合剂，可用作膳食成分，可从废活性污泥（WAS）絮凝体中提取多价金属离子，可增强废活性污泥中挥发性脂肪酸的产生。
T26551	Acetyl-L-carnitine RO 447190,L-Acetylcarnitine,LAC,L-O-Acetylcarnitine,ALCAR,Acetyl L carnitine	Endogenous Metabolite	Metabolism
	Acetyl-L-carnitine(RO 447190) 是一种可透过血脑屏障的氨基酸左旋肉碱，常作为膳食补充剂，对神经炎症有益。Acetyl-L-carnitine 具有神经保护作用，可用以研究像阿尔茨海默病类的神经疾病。
T13730	Hydroxocobalamin acetate	Others	Others
	Hydroxocobalamin acetate 是可注射的天然维生素 B12，其不良反应特征良好，可用于研究维生素 B12 缺乏症 (包括恶性贫血) 。
T6267	Lomitapide AEGR-733,洛美他派,BMS-201038	CETP	Metabolism
	Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。
T71704	Navamepent RX-10045	Others	Others
	Navamepent (RX-10045) 是 resolvin E1 (一种膳食-3多不饱和脂肪酸代谢物)的类似物，具有强大的抗炎活性，可减少角膜炎症、上皮损伤，加速角膜组织修复。Navamepent 可抑制角膜上皮细胞释放几种关键促炎介质。Navamepent 对干眼和杯状细胞损失非常有效，可加速泪液的产生。
T26273	Thioquinapiperifil KF-31327,KF 31327,KF-31327 free base,KF31327	Others	Others
	Thioquinapiperifil is a type of phosphodiesterase-5 (PDE-5) inhibitor found in dietary supplements.
T29689	AFB1-N7-guanine	Others	Others
	In epidemiological studies, Aflatoxin B1-N7-guanine serum albumin adducts have been established as biomarkers of dietary aflatoxin exposure.
T84570	11-dehydro Thromboxane B3 11-dehydro TXB3	Others	Others
	11-Dehydro Thromboxane B3 (11-dehydro TXB3) serves as a urinary metabolite of TXA3 in humans following an increased dietary intake of EPA.
T37120	1,2,3-Triundecanoyl Glycerol	Others	Others
	1,2,3-Triundecanoyl glycerol is a triacylglycerol that contains undecanoic acid at thesn-1,sn-2, andsn-3 positions. Dietary administration of a 7:3 (w/w) mixture of 1,2,3-triundecanoyl glycerol and corn oil prevents fasting-induced decreases in plasma glucose, alanine, and insulin levels, as well as the ratio of insulin to glucagon, in rats compared with dietary administration of corn oil alone.1 1.Pi-Sunyer, F.X., Conway, J.M., Lavau, M., et al.Glucagon, insulin, and gluconeogenesis in fasted o...
T37383	1,2,3-Trilinoelaidoyl-rac-glycerol	Others	Others
	1,2,3-Trilinoelaidoyl-rac-glycerol is a triacylglycerol that contains linoelaidic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trilinoelaidoyl-rac-glycerol (0.6-6.3% w/w) lowers serum levels of thromboxane B2 , prostaglandin F2 (PGF2), and PGE in rats.1 \|1. Bruckner, G., Goswami, S., and Kinsella, J.E. Dietary trilinoelaidate: Effects on organ fatty acid composition, prostanoid biosynthesis and platelet function in rats. J. Nutr. 114(1), 58-67 (1984).
T81473	Phytochelatin 6 PC 6
	Phytochelatin 6是一种植物所产生的金属结合化合物，其可能降低（如镉）等膳食有毒金属的生物利用度。
T37125	1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol	Others	Others
	1,3-Dipalmitoyl-2-eicosapentaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position. Dietary administration of 1,3-dipalmitoyl-2-eicosapentaenoyl-rac-glycerol decreases hepatic triacylglycerol levels in mice.
T36765	Palmitelaidic Acid methyl ester	Others	Others
	Palmitoleic acid is a common constituent of the triglycerides of human adipose tissue. Palmitoleic acid-based diets raise low-density lipoprotein cholesterol and diminish high-density lipoprotein cholesterol, even when dietary intake of cholesterol is maintained at a low level. Palmitelaidic acid is the trans isomer of the 16:1 fatty acid palmitoleic acid. While its effects on cholesterol levels are poorly studied, palmitelaidic acid can have very different effects from those of palmitoleic acid...
T81472	Phytochelatin 6 TFA PC 6 TFA
	Phytochelatin 6 TFA为植物合成的金属结合化合物，具有降低如镉等膳食有毒金属的生物可利用性的潜能。
T85190	all-cis-4,7,10,13,16-Docosapentaenoic Acid ethyl ester SFE 24:5,all-cis-4,7,10,13,16-DPA ethyl ester	Others	Others
	All-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester (all-cis-4,7,10,13,16-DPA ethyl ester) is a derivative of docosapentaenoic acid (DPA), an omega-3 fatty acid prevalent in fish oils. This ethyl ester form is commonly included in dietary supplements formulations to enhance omega-3 fatty acid intake.
T20016	Diuron HW 920,Dirurol,Karmex,Lucenit,Marmer,Seduron	Others	Others
	Diuron is a Phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (25 nM/ml) decreases total respiration in roots of wheat by 50% and ground respiration by 100%. Diuron (2,500 ppm, dietary) increases the inc
T81475	Phytochelatin 5 PC 5
	Phytochelatin 5为植物合成的金属结合化合物，具有可能降低如镉等膳食有毒金属的生物利用度。
T36230	C2 Ceramide (d14:1/2:0) C2 Ceramide (d14:1/2:0)	Others	Others
	C2 Ceramide (d14:1/2:0) is a bioactive sphingolipid. Dietary administration of C2 ceramide (d14:1/2:0) (100 μM) induces lipotoxic cardiomyopathy via increasing diastolic and systolic diameter as well as reducing fractional shortening and the number of normal cardiac contractile events in Drosophila.
T85229	1,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol TG(16:0/22:6/16:0),1,3-Palmitin-2-Docoahexaenoin,16:0/22:6/16:0-TG	Others	Others
	1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to decrease hepatic triglyceride and cholesterol levels in mice.
T36300	Uridine-5’-monophosphate (sodium salt hydrate)	Others	Others
	Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements. 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002)
T37371	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid	Others	Others
	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.
T25496	Hexaglutamate folate Pteglu6	Others	Others
	Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in humans results in anemia, neural tube
T35620	Ethoxyquin Dimer	Others	Others
	Ethoxyquin dimer is an antioxidant and metabolite of ethoxyquin .1 It prevents oxidation of polyunsaturated fatty acids in fish meal and fish oil. Dietary administration of ethoxyquin dimer (0.1, 0.3, and 0.5% w/w) induces microvesicular steatosis and hepatocyte necrosis, as well as increases liver levels of oxidized glutathione and total lipids in mice.2
T81474	Phytochelatin 5 TFA PC 5 TFA
	Phytochelatin 5 TFA为植物合成的金属结合化合物，有潜在降低食物中有毒金属（例如镉）生物可利用性的作用。
T85135	1,2,3-Tritridecanoyl Glycerol Tritridecanoin,TG(13:0/13:0/13:0),13:0/13:0/13:0-TG,Glycerol Tritridecanoyl,13:0 TAG	Others	Others
	1,2,3-Tritridecanoyl glycerol, a synthetic triacylglycerol featuring tridecanoic acid at the sn-1, sn-2, and sn-3 positions, serves as a standard for relative triacylglycerols quantification in C. elegans fat stores and as an internal standard in quantifying triacylglycerols in serum and liver of adult rat offspring exposed to dietary conjugated linoleic acids during and post-gestation.
T37229	(±)8,9-DiHETE	Others	Others
	(±)8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid .[1] It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases. Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.[2]
T75328	Hydroxocobalamin hydrochloride	Others	Others
	Hydroxocobalamin hydrochloride 是天然维生素B12的可注射形式，因其优良的安全性质，被用于研究维生素B12缺乏症（包括恶性贫血）相关治疗。
T37532	Docosahexaenoyl Glycine
	The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.
T38259	Phenelfamycin E	Others	Others
	Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) increases survival in a mouse model of lethal S. pyogenes infection in a dose-dependent manner. Dietary administration of phenelfamycin E increases body weight in chickens.
T35603	Oleic Acid-2,6-diisopropylanilide	Others	Others
	AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM. When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%.
T84632	9(E),11(E)-Conjugated Linoleic Acid 9E,11E-CLA	Others	Others
	9(E),11(E)-Conjugated Linoleic Acid (9(E),11(E)-CLA) belongs to a group of eight geometric isomers of linoleic acid, characterized by adjacent double bonds. This specific isomer, 9,11 all-trans linoleic acid, was first discovered in ground beef and is found in various dairy products as well. Notably, it has been shown to decrease mammary tumors in rats with dietary inclusion as minimal as 0.1%. [Matreya, LLC. Catalog No. 1181]
T35881	Resolvin E2	Others	Others
	Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in m...
T80951	Trevogrumab REGN-1033
	Trevogrumab (REGN-1033) 是针对GDF8（即生长分化因子8，亦称为肌肉生长抑制素）的单克隆抗体。该化合物目前主要用于研究包括废用性萎缩、慢性疾病以及饮食及营养摄入变化等原因引起的肌肉减少症。
T37754	Avilamycin A	Others	Others
	Avilamycin A is an antibiotic.1 It is active against veterinary isolates of C. perfringens (MICs = ≤0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml).1,2 Dietary administration of avilamycin A (15 and 30 ppm) reduces mortality in a broiler cockerel model of C. perfringens infection.3 Formulations containing avilamycin A have been used in the prevention of necrotic enteritis in livestock. \|1. Watkins, K.L., Shryock, T.R., Dearth, R.N., et al. In-vitro antimicrobial susceptibility of Cl...
T35997	22-HDHA	Others	Others
	22-HDHA is an oxidation product of docosahexaenoic acid . In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
T37554	Oleyl Anilide	Others	Others
	AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransferase (ACAT) with an IC50 of 26 μM. OA and the related glyceride dioleoyl phenylamino propane 1,2-diol have been linked to a syndrome of eosinophilia, excessive T-cell activation, and elevated interleukin-4 (IL-4), soluble IL-2R, and IL-5. The clinical consequences are an acute pulm...
T84431	9-SAHSA	Others	Others
	Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids that are modulated by dietary changes such as fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds generally consist of a fatty acid chain of either 16 or 18 carbons (for example, palmitoleic, palmitic, oleic, or stearic acid) esterified to a similarly long hydroxy fatty acid. One specific FAHFA, 9-SAHSA, features stearic acid esterified at the 9th carbon of hydroxy stearic acid. The concent...
T84424	5-SAHSA	Others	Others
	15-SAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), is recognized for its involvement in metabolic regulation. This compound comprises stearic acid esterified to 5-hydroxy stearic acid and is notably influenced by dietary changes, such as fasting and high-fat consumption, with a link to insulin sensitivity. SAHSA levels are specifically found to be moderately increased in the serum of AG4OX mice, which are characterized by their glucose tolerance through the overexpression of ...
TP2190	vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]	Others	Others
	Vitamin D-binding protein is a multifunctional, highly expressed, polymorphic serum protein. These range from the transport of vitamin D metabolites to possible roles in the immune system and host defense. The molecular weight range, the time course of ap
T79919	S-Adenosyl-L-methionine (1,4-butanedisulfonate) Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)	Endogenous Metabolite	Metabolism
	S-Adenosyl-L-methionine (S-Adenosyl methionine) 1,4-butanedisulfonate 作为一种口服活性的甲基供体，它是一种膳食补充剂，对抗抑郁和缓解疼痛具有显著功效。此化合物在癌症治疗中显示了抗增殖、促进凋亡和阻止转移的潜在作用。同时，S-Adenosyl-L-methionine 1,4-butanedisulfonate 也用于肝病和骨关节炎的相关研究。
T84432	12-SAHSA	Others	Others
	Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids recently discovered to be modulated by dietary influences such as fasting and high-fat feeding, and they play a role in enhancing insulin sensitivity. These compounds typically feature a carbon-16 or carbon-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) esterified to a carbon-16 or carbon-18 hydroxy fatty acid. A specific example is 12-SAHSA, which consists of stearic acid linked to 12-hydroxy stearic acid...

化合物

Iron(II) fumarate

Cat.No: T0001

Synonym: Ferrous fumarate,Iron Fumarate,富马酸铁 (II),富马酸亚铁

Target: Others

Propionylcarnitine

Cat.No: T19528

Synonym: Propionyl carnitine

Target: Others

Cat.No: T1593

Synonym: 依泽替米贝,SCH 58235

Target: Others, Nrf2, NPC1L1, Autophagy

Cat.No: T0490

Synonym: Diabinese,氯磺丙脲

Target: ATPase, ABC

Sevelamer hydrochloride

Cat.No: T6344

Synonym: Sevelamer HCl

Target: FXR, Autophagy

Levomefolate calcium

Cat.No: T7593

Synonym: 左旋甲状腺素钙,L-5-甲基四氢叶酸钙

Target: Antifolate

(±)-Propionylcarnitine chloride

Cat.No: T22484

Synonym: Propionyl-DL-carnitine chloride

Target: Endogenous Metabolite

Cat.No: T1129

Synonym: Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺

Target: Others

Thiamine disulfide

Cat.No: T20062

Synonym: 二硫化硫胺,TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

Tetrasodium glutamate diacetate

Cat.No: T20266

Synonym: Glutamate diacetate tetrasodium,GLDA

Target: Others

Acetyl-L-carnitine

Cat.No: T26551

Synonym: RO 447190,L-Acetylcarnitine,LAC,L-O-Acetylcarnitine,ALCAR,Acetyl L carnitine

Target: Endogenous Metabolite

Hydroxocobalamin acetate

Cat.No: T13730

Target: Others

Cat.No: T6267

Synonym: AEGR-733,洛美他派,BMS-201038

Target: CETP

Cat.No: T71704

Synonym: RX-10045

Target: Others

Thioquinapiperifil

Cat.No: T26273

Synonym: KF-31327,KF 31327,KF-31327 free base,KF31327

Target: Others

AFB1-N7-guanine

Cat.No: T29689

Target: Others

11-dehydro Thromboxane B3

Cat.No: T84570

Synonym: 11-dehydro TXB3

Target: Others

1,2,3-Triundecanoyl Glycerol

Cat.No: T37120

Target: Others

1,2,3-Trilinoelaidoyl-rac-glycerol

Cat.No: T37383

Target: Others

Phytochelatin 6

Cat.No: T81473

Synonym: PC 6

1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol

Cat.No: T37125

Target: Others

Palmitelaidic Acid methyl ester

Cat.No: T36765

Target: Others

Phytochelatin 6 TFA

Cat.No: T81472

Synonym: PC 6 TFA

all-cis-4,7,10,13,16-Docosapentaenoic Acid ethyl ester

Cat.No: T85190

Synonym: SFE 24:5,all-cis-4,7,10,13,16-DPA ethyl ester

Target: Others

Cat.No: T20016

Synonym: HW 920,Dirurol,Karmex,Lucenit,Marmer,Seduron

Target: Others

Phytochelatin 5

Cat.No: T81475

Synonym: PC 5

C2 Ceramide (d14:1/2:0)

Cat.No: T36230

Synonym: C2 Ceramide (d14:1/2:0)

Target: Others

1,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol

Cat.No: T85229

Synonym: TG(16:0/22:6/16:0),1,3-Palmitin-2-Docoahexaenoin,16:0/22:6/16:0-TG

Target: Others

Uridine-5’-monophosphate (sodium salt hydrate)

Cat.No: T36300

Target: Others

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid

Cat.No: T37371

Target: Others

Hexaglutamate folate

Cat.No: T25496

Synonym: Pteglu6

Target: Others

Ethoxyquin Dimer

Cat.No: T35620

Target: Others

Phytochelatin 5 TFA

Cat.No: T81474

Synonym: PC 5 TFA

1,2,3-Tritridecanoyl Glycerol

Cat.No: T85135

Synonym: Tritridecanoin,TG(13:0/13:0/13:0),13:0/13:0/13:0-TG,Glycerol Tritridecanoyl,13:0 TAG

Target: Others

Cat.No: T37229

Target: Others

Hydroxocobalamin hydrochloride

Cat.No: T75328

Target: Others

Docosahexaenoyl Glycine

Cat.No: T37532

Phenelfamycin E

Cat.No: T38259

Target: Others

Oleic Acid-2,6-diisopropylanilide

Cat.No: T35603

Target: Others

9(E),11(E)-Conjugated Linoleic Acid

Cat.No: T84632

Synonym: 9E,11E-CLA

Target: Others

Cat.No: T35881

Target: Others

Cat.No: T80951

Synonym: REGN-1033

Cat.No: T37754

Target: Others

Cat.No: T35997

Target: Others

Cat.No: T37554

Target: Others

Cat.No: T84431

Target: Others

Cat.No: T84424

Target: Others

vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]

Cat.No: TP2190

Target: Others

S-Adenosyl-L-methionine (1,4-butanedisulfonate)

Cat.No: T79919

Synonym: Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)

Target: Endogenous Metabolite

Cat.No: T84432

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5372	L-SelenoMethionine L-(+)-Selenomethionine,L-硒代蛋氨酸	Apoptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体，是硒的主要天然食物形式。它是一种癌症化学预防剂，可以增加谷胱甘肽过氧化物酶的表达，还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。
T13795	Nicotinamide riboside	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Nicotinamide riboside 是维生素 B3 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体，增加 NAD+水平并激活SIRT1和SIRT3，可用于研究阿尔茨海默氏病的认知退化。
T2207	Adrenosterone 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G	Androgen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物，由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素，具有较弱的雄激素特性。它是一种膳食补充剂，能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。
T1286	Vincamine Angiopac,Oxybral,Devincan,Novicet,Equipur,长春胺,Perval	GPR; Others	Endocrinology/Hormones; GPCR/G Protein; Others
	Vincamine (Perval) 是从长春花中提取的单萜类吲哚生物碱，可作为外周血管扩张剂，对脑微血管循环有选择性的血管调节作用。它可改善体内葡萄糖稳态，对 2 型糖尿病具有研究潜力。它是GPR40激动剂，通过改善 β 细胞功能障碍和促进葡萄糖刺激型胰岛素分泌发挥 β 细胞保护作用。
T6220	Nicotinamide riboside chloride 烟酰胺核糖氯酸盐,烟酰胺核苷	Sirtuin; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nicotinamide riboside Chloride 是维生素 B3 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体，增加 NAD+水平并激活SIRT1和SIRT3，可用于研究阿尔茨海默氏病的认知退化。
T7475	S-Adenosyl-L-methionine AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸	Others; Endogenous Metabolite	Metabolism; Others
	S-Adenosyl-L-methionine (Ademetionine) 是一种具有有效的抗抑郁和减轻疼痛作用的膳食补充剂，是通过蛋氨酸腺苷转移酶的作用由蛋氨酸和 ATP 内源性生产的，是一种重要的口服具有活力的甲基供体，能够用于肝病和骨关节炎的研究。
T19608	Zinc sulfate heptahydrate	Others	Others
	Zinc sulfate heptahydrate 是七水合形式的硫酸锌，是一种膳食补充剂，可用于锌缺乏症和预防高危人群的锌缺乏症。
T22293	Chondroitine sulfate Chondroitine sulfate (From cattle)	Others	Others
	Chondroitine sulfate 是软骨的重要结构成分，已被用作治疗关节不适的膳食补充剂。
T19775	Trilaurin Tridodecanoin,NSC 4061,Glyceryl tridodecanoate,Trilauroylglycerol,Glycerol trilaurate, Glyceryl trilaurate,甘油三酯,1,2,3-Tridodecanoylglycerol	Others	Others
	Trilaurin (Glyceryl tridodecanoate) 是一种存在于膳食脂肪中的甘油三酯。三月桂酸甘油酯可用作化妆品中的增稠剂。
TN6752	Dimethyl sulfone	Endogenous Metabolite	Metabolism
	Dimethyl sulfone 是内源性代谢产物的一种。
T2840	Phloracetophenone 2,4,6-三羟基苯乙酮,2,4,6-trihydroxyacetophenone,1-(2,4,6-Trihydroxyphenyl)ethanone	Others; P450; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; Others
	Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) 是多叶姜黄中苯乙酮糖苷的糖苷配基部分，具有抗肥胖，降血脂和降低胆固醇作用，能够增强胆固醇 7α-羟化酶的活性。
T0579	Myricetin Cannabiscetin,杨梅素	Apoptosis; PI3K; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Metabolism; PI3K/Akt/mTOR signaling
	Myricetin (Cannabiscetin) 是一种存在于常见植物中的类黄酮，具有强抗氧化，抗糖尿病，抗癌和抗炎活性。
T13516	5-Methyltetrahydrofolic acid 甲基叶酸盐,5-Methyl THF	Endogenous Metabolite	Metabolism
	5-Methyltetrahydrofolic acid (5-Methyl THF) 是四氢叶酸的甲基化衍生物，具有生物活性。5-Methyltetrahydrofolic acid 是主要的天然膳食叶酸，是血浆和脑脊液中叶酸的主要形式。
T13808	p-Coumaric Acid Ethyl Ester 对香豆酸乙酯,Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate	Others; Drug Metabolite	Metabolism; Others
	p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) 是 p-Coumaric acid 的乙酯形式。p-Coumaric Acid 是一种免疫抑制剂，能够用于自身免疫性炎性疾病 (如类风湿关节炎) 的研究。
T3768	Epifriedelanol 表木栓醇,Epifriedelinol	Others	Others
	Epifriedelanol (Epifriedelinol) 是一种分离自 Ulmus davidiana 根皮中的三萜类化合物，具有抗肿瘤作用，可以减缓人原始细胞的衰老。
T4238	Glycocyamine 乙酸胍,2-Guanidinoacetic acid,Guanidoacetic acid	Others; Endogenous Metabolite	Metabolism; Others
	Glycocyamine (2-Guanidinoacetic acid) 是一种肌酸的前体，能够为鸟类的体内平衡提供能量，也能够成为食用精氨酸的替代物。
T5242	Triarachidin Triarachin,1,2,3-Trieicosanoyl Glycerol,Glycerol Trieicosanoate,三花生精	Others; Endogenous Metabolite	Metabolism; Others
	Triarachidin (1,2,3-Trieicosanoyl Glycerol) 是内源性代谢产物的一种。
T0200	α-Lipoic Acid Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸	Apoptosis; NF-κB; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite	Apoptosis; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	α-Lipoic Acid (DL-α-Lipoic acid) 是线粒体酶复合物的重要辅助因子，是一种抗氧化剂，可抑制NF-κB 依赖性的HIV-1LTR 活化。它还可诱导内质网应激介导的肝癌细胞凋亡。
T0978	Pantethine LBF disulfide,Pantosin,Pantetina,Bis-pantethine,泛硫乙胺(维生素B5),泛硫乙胺,Pantomin,D-Pantethine	Endogenous Metabolite	Metabolism
	D-Pantethine (Pantomin) 是泛酸的二聚体形式, 是生产辅酶 A 的中间体。D-Pantethine 能够作为膳食补充剂，用于改善血液胆固醇和研究痤疮。
T4129	Arachidonic acid Immunocytophyte,花生四烯酸,arachidonate,Immunocytophyt,Vevodar	Others; Endogenous Metabolite	Metabolism; Others
	Arachidonic acid (Immunocytophyte) 属于天然产物，是一种不饱和的必需脂肪酸，是动物磷脂的成分。Arachidonic acid 由膳食亚油酸合成而成，是前列腺素、血栓素和白三烯生物合成的前体。
TWO2727	Propane-1,2,3-triyl tripalmitate Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯	Others; Endogenous Metabolite	Metabolism; Others
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) 是内源性代谢产物的一种。
T4717	25-Hydroxycholesterol 25-羟基胆固醇,25-羟基胆甾醇	Others; Endogenous Metabolite; HMG-CoA Reductase	Metabolism; Others
	25-Hydroxycholesterol 是胆固醇的代谢产物，由巨噬细胞响应 Toll 样受体激活而分泌。它有效抑制 B 细胞产生 IgA，EC50约为 65 nM。
T4909	N-Acetyl-DL-methionine N-乙酰-DL-蛋氨酸,N-乙酰-DL-甲硫氨酸	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-DL-methionine 是内源性代谢产物的一种。
T6S0221	Eriocitrin eriodictyol 7-rutinoside,圣草次甙,Eriodictyol-7-O-Rutinoside,Eriodictioside,圣草次甙；圣草次苷,Eriodictyol glycoside	Apoptosis; Carbonic Anhydrase	Apoptosis; Metabolism
	Eriocitrin (Eriodictyol-7-O-Rutinoside) 是从柠檬中分离出来的一种黄酮类天然产物，是强效的抗氧化剂。它通过激活线粒体涉及的内在信号传导途径来触发细胞凋亡。它通过上调 p53、cyclin A、cyclin D3 和 CDK6 使 S 期细胞周期停滞，从而抑制肝癌细胞的增殖。
T0934	Nicotinamide Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP	Sirtuin; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nicotinamide 是维生素 B3 的吡啶核苷形式，可作为烟酰胺腺嘌呤二核苷酸或 NAD+ 的前体，可通过膳食摄入来补充，能预防或治疗黑舌病和糙皮病。
T5S1177	Aloin B Isobarbaloin,芦荟苷B,芦荟素B	Others	Others
	Aloin B (Isobarbaloin) 是一种芦荟素的异构体。其中芦荟素是芦荟中的具生理活性蒽醌化合物。
T1183	Retinol all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin	Others	Others
	Retinol (Vitamin A) 属于天然维生素，具有脂溶性。Retinol 在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。
T3578	Pyridoxal phosphate PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式，可抑制逆转录酶活性，用于研究迟发性运动障碍症。
TN1853	Lariciresinol (+)-落叶松树脂醇	VEGFR; Antifection	Angiogenesis; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Lariciresinol 是一种肠木脂素前体，它通过破坏真菌质膜具有杀真菌活性，并具有作为治疗人类真菌感染性疾病的新型抗真菌剂的治疗潜力。膳食 lariciresinol 可以减缓乳腺肿瘤的生长并降低人 MCF-7 乳腺癌异种移植物和致癌物诱导的大鼠乳腺肿瘤的血管密度。
T2836	Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin	MEK; PI3K; Endogenous Metabolite	MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Isorhamnetin (3-methylquercetin) 是从中草药沙棘中提取的一种类黄酮，可通过抑制MEK1和PI3K 来抑制皮肤癌。
TN1564	Delphinidin 3-glucoside chloride Delphinidin-3-O-glucoside chloride	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) 是从 Hibiscus sabdariffa 提取物中发现的膳食酚类物质。Delphinidin 3-glucoside chloride 具有抗氧化活性，可诱导 B 细胞慢性淋巴细胞性白血病 (B CLL) 的促凋亡作用，抑制 EGFR，抑制血小板聚集。Delphinidin 3-glucoside chloride 具有抗肿瘤活性，通过调节 pAKT/IRF1/HOTAIR 通路发挥作用。
T2966	Beta-Sitosterol Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost	Apoptosis; Lipase; Endogenous Metabolite	Apoptosis; Metabolism
	Beta-Sitosterol (SKF 14463) 属于天然产物，是一种植物甾醇，广泛存在于植物界。Beta-Sitosterol 的摄人量与许多慢性病的发生率有关系，比如具有明显降低血清胆固醇的功效。
T8098	γ-Hexalactone γ-caprolactone,gamma-己内酯,γ-己内酯	Others	Others
	γ-Hexalactone (γ-caprolactone) 是一种存在成熟水果中的 gamma 内酯。它会导致 DNA 损伤，可用作对氧磷酶 1 的底物 (PON1)。
T4938	Potassium 1H-indol-3-yl sulfate 硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate	AhR; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) 是人芳烃受体(AhR)的激动剂。芳烃受体(AhR)最近被发现是免疫炎症条件的病理生理调节剂，Potassium 1H-indol-3-yl sulfate 已被证明是AhR的配体。Potassium 1H-indol-3-yl sulfate 也是膳食蛋白质中色氨酸的代谢物。色氨酸被肠道细菌代谢为吲哚，吲哚被吸收到血液中，然后在肝脏中进一步代谢为硫酸吲哚，通常通过尿液排出体外。在肾功能受损的慢性肾病患者中，Potassium 1H-indol-3-yl sulfate 可作为尿毒症毒素在血清中积累，诱导氧化应激并加速疾病进展。250 μM Potassium 1H-indol-3-yl sulfate 可诱导NF-Κb活化，促进大鼠近端小管细胞TGF-β1和Smad3的表达，与促纤维化活性相关。
TN6612	Delphinidin-3-O-arabinoside chloride
	Delphinidin-3-O-arabinoside chloride is a dietary antioxidant.
TN1590	DL-alpha-Tocopherylacetate
	Dl-alpha-tocopheryl acetate is a dietary supplement.
T35400	β-Muricholic Acid β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid	Others	Others
	β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.[4]
T19186	Aldosterone	Others	Others
	Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.
T13731	Hydroxocobalamin monohydrochloride Vitamin B12a monohydrochloride,盐酸羟钴胺	Others	Others
	Hydroxocobalamin monohydrochloride is an injectable naturally occurring form of vitamin B12. It is used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia.
T19169	9-cis-Retinal	Others	Others
	9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and maturation of rod photoreceptors in r
TN2060	Petunidin-3-O-glucoside chloride	Others	Others
	Petunidin-3-O-glucoside chloride has significantly higher antioxidant activity than the Fe2+ control. Petunidin-3-O-glucoside causes problems in digestibility, may be important dietary supplements with beneficial health effects.
T78476	Hydroxocobalamin Vitamin B12a	Endogenous Metabolite	Metabolism
	Hydroxocobalamin（Vitamin B12a）为可注射型天然维生素B12，不良反应特性良好，适用于治疗维生素B12缺乏症（包括恶性贫血）的膳食补充。
TN3968	Epifriedelanol acetate	Others	Others
	Epifriedelanol exhibits antibacterial activities. It also can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol and friedel
TN3070	4beta-Hydroxywithanolide E	PARP; HSP; NF-κB; COX	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by mo
TN7261	Tridocosahexaenoylglycerol TG-DHA,Meganol D	Others	Others
	Tridocosahexaenoylglycerol (TG-DHA)是一种改善小鼠自身免疫性脑脊髓炎的口服有效膳食补充剂，展现出对神经退行性疾病的有益作用，并能改善糖尿病视网膜病变黄斑功能。该化合物在神经系统性疾病、炎症免疫疾病以及代谢性疾病研究中具有应用潜力。
T38330	Collinin	Others	Others
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
T37609	(rel)-Asperparaline A	Others	Others
	Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces...
T36563	(E)-Guggulsterone	Others	Others
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy...

天然产物

L-SelenoMethionine

Cat.No: T5372

Synonym: L-(+)-Selenomethionine,L-硒代蛋氨酸

Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite

Nicotinamide riboside

Cat.No: T13795

Target: Sirtuin

Cat.No: T2207

Synonym: 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G

Target: Androgen Receptor, Endogenous Metabolite

Cat.No: T1286

Synonym: Angiopac,Oxybral,Devincan,Novicet,Equipur,长春胺,Perval

Target: GPR, Others

Nicotinamide riboside chloride

Cat.No: T6220

Synonym: 烟酰胺核糖氯酸盐,烟酰胺核苷

Target: Sirtuin, Endogenous Metabolite

S-Adenosyl-L-methionine

Cat.No: T7475

Synonym: AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸

Target: Others, Endogenous Metabolite

Zinc sulfate heptahydrate

Cat.No: T19608

Target: Others

Chondroitine sulfate

Cat.No: T22293

Synonym: Chondroitine sulfate (From cattle)

Target: Others

Cat.No: T19775

Synonym: Tridodecanoin,NSC 4061,Glyceryl tridodecanoate,Trilauroylglycerol,Glycerol trilaurate, Glyceryl trilaurate,甘油三酯,1,2,3-Tridodecanoylglycerol

Target: Others

Dimethyl sulfone

Cat.No: TN6752

Target: Endogenous Metabolite

Phloracetophenone

Cat.No: T2840

Synonym: 2,4,6-三羟基苯乙酮,2,4,6-trihydroxyacetophenone,1-(2,4,6-Trihydroxyphenyl)ethanone

Target: Others, P450, Antibacterial, Antibiotic

Cat.No: T0579

Synonym: Cannabiscetin,杨梅素

Target: Apoptosis, PI3K, Endogenous Metabolite, Autophagy

5-Methyltetrahydrofolic acid

Cat.No: T13516

Synonym: 甲基叶酸盐,5-Methyl THF

Target: Endogenous Metabolite

p-Coumaric Acid Ethyl Ester

Cat.No: T13808

Synonym: 对香豆酸乙酯,Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate

Target: Others, Drug Metabolite

Cat.No: T3768

Synonym: 表木栓醇,Epifriedelinol

Target: Others

Cat.No: T4238

Synonym: 乙酸胍,2-Guanidinoacetic acid,Guanidoacetic acid

Target: Others, Endogenous Metabolite

Cat.No: T5242

Synonym: Triarachin,1,2,3-Trieicosanoyl Glycerol,Glycerol Trieicosanoate,三花生精

Target: Others, Endogenous Metabolite

Cat.No: T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

Cat.No: T0978

Synonym: LBF disulfide,Pantosin,Pantetina,Bis-pantethine,泛硫乙胺(维生素B5),泛硫乙胺,Pantomin,D-Pantethine

Target: Endogenous Metabolite

Arachidonic acid

Cat.No: T4129

Synonym: Immunocytophyte,花生四烯酸,arachidonate,Immunocytophyt,Vevodar

Target: Others, Endogenous Metabolite

Propane-1,2,3-triyl tripalmitate

Cat.No: TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯

Target: Others, Endogenous Metabolite

25-Hydroxycholesterol

Cat.No: T4717

Synonym: 25-羟基胆固醇,25-羟基胆甾醇

Target: Others, Endogenous Metabolite, HMG-CoA Reductase

N-Acetyl-DL-methionine

Cat.No: T4909

Synonym: N-乙酰-DL-蛋氨酸,N-乙酰-DL-甲硫氨酸

Target: Others, Endogenous Metabolite

Cat.No: T6S0221

Synonym: eriodictyol 7-rutinoside,圣草次甙,Eriodictyol-7-O-Rutinoside,Eriodictioside,圣草次甙；圣草次苷,Eriodictyol glycoside

Target: Apoptosis, Carbonic Anhydrase

Cat.No: T0934

Synonym: Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP

Target: Sirtuin, Endogenous Metabolite

Cat.No: T5S1177

Synonym: Isobarbaloin,芦荟苷B,芦荟素B

Target: Others

Cat.No: T1183

Synonym: all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin

Target: Others

Pyridoxal phosphate

Cat.No: T3578

Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

Cat.No: TN1853

Synonym: (+)-落叶松树脂醇

Target: VEGFR, Antifection

Cat.No: T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

Delphinidin 3-glucoside chloride

Cat.No: TN1564

Synonym: Delphinidin-3-O-glucoside chloride

Target: Apoptosis, EGFR

Beta-Sitosterol

Cat.No: T2966

Synonym: Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost

Target: Apoptosis, Lipase, Endogenous Metabolite

Cat.No: T8098

Synonym: γ-caprolactone,gamma-己内酯,γ-己内酯

Target: Others

Potassium 1H-indol-3-yl sulfate

Cat.No: T4938

Synonym: 硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate

Target: AhR, Endogenous Metabolite

Delphinidin-3-O-arabinoside chloride

Cat.No: TN6612

DL-alpha-Tocopherylacetate

Cat.No: TN1590

β-Muricholic Acid

Cat.No: T35400

Synonym: β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid

Target: Others

Cat.No: T19186

Target: Others

Hydroxocobalamin monohydrochloride

Cat.No: T13731

Synonym: Vitamin B12a monohydrochloride,盐酸羟钴胺

Target: Others

Cat.No: T19169

Target: Others

Petunidin-3-O-glucoside chloride

Cat.No: TN2060

Target: Others

Hydroxocobalamin

Cat.No: T78476

Synonym: Vitamin B12a

Target: Endogenous Metabolite

Epifriedelanol acetate

Cat.No: TN3968

Target: Others

4beta-Hydroxywithanolide E

Cat.No: TN3070

Target: PARP, HSP, NF-κB, COX

Tridocosahexaenoylglycerol

Cat.No: TN7261

Synonym: TG-DHA,Meganol D

Target: Others

Cat.No: T38330

Target: Others

(rel)-Asperparaline A

Cat.No: T37609

Target: Others

(E)-Guggulsterone

Cat.No: T36563

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01636	MGAM Protein, Human, Recombinant (aa 960-1853, His) Alpha-1,4-glucosidase,Maltase-glucoamylase,MGAM	Human	Baculovirus Insect Cells
	May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing.
TMPH-00491	PNLIPRP1 Protein, Canine, Recombinant (His) Inactive pancreatic lipase-related protein 1,PNLIPRP1	Canine	P. pastoris (Yeast)
	May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro). PNLIPRP1 Protein, Canine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.7 kDa and the accession number is P06857.
TMPH-00492	PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) Inactive pancreatic lipase-related protein 1,PNLIPRP1	Canine	E. coli
	May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro). PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.7 kDa and the accession number is P06857.
TMPH-01635	MGAM Protein, Human, Recombinant (aa 87-954, His) MGAM,Maltase-glucoamylase,Alpha-1,4-glucosidase	Human	Baculovirus Insect Cells
	May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. MGAM Protein, Human, Recombinant (aa 87-954, His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 101.1 kDa and the accession number is O43451.
TMPH-01678	MMUT Protein, Human, Recombinant (His) MMUT,Methylmalonyl-CoA mutase, mitochondrial,Methylmalonyl-C...	Human	E. coli
	Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle. MMUT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.8 kDa and the accession number is P22033.
TMPJ-00479	KHK Protein, Human, Recombinant (His) KHK,Hepatic fructokinase,Ketohexokinase	Human	HEK293 Cells
	Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.
TMPK-00150	FOLR1 Protein, Human, Recombinant (His & Avi) Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a...	Human	HEK293 Cells
	Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t...
TMPY-03222	PNLIP Protein, Human, Recombinant (His) PL,pancreatic lipase,PTL,PNLIPD	Human	HEK293 Cells
	PNLIP is an enzyme that belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which a...
TMPY-02223	GSTM2 Protein, Human, Recombinant (His) GSTM2-2,GTHMUS,glutathione S-transferase mu 2 (muscle),GSTM,...	Human	E. coli
	Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si...
TMPY-02622	Aldolase B Protein, Human, Recombinant (GST) aldolase B, fructose-bisphosphate,ALDO2,ALDB	Human	E. coli
	The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed in several human diseases and cancer types. Via GATA6, metastatic cells in the liver upregulate the enzyme aldolase B (ALDOB), which enhances fructose metabolism and provides fuel for major pathways of central carbon metabolism during tumor cell proliferation. Targeting ALDOB or...
TMPY-01579	GBA3 Protein, Human, Recombinant (His) glucosidase, beta, acid 3 (gene/pseudogene),GBA3,MGC126878,K...	Human	Baculovirus Insect Cells
	Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in r...
TMPY-00963	ASAH2 Protein, Mouse, Recombinant (His) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) ...	Mouse	HEK293 Cells
	ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 po...
TMPY-03353	CEL Protein, Mouse, Recombinant (His) 1810036E18Rik,carboxyl ester lipase,BAL	Mouse	Baculovirus Insect Cells
	CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL c...
TMPJ-01351	XPNPEP1 Protein, Human, Recombinant (His) Xaa-Pro Aminopeptidase 1,X-Prolyl Aminopeptidase 1 Soluble,A...	Human	E. coli
	X-Prolyl Aminopeptidase (XPNPEP1) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-Prolyl Aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby compleme...
TMPY-02051	FABP2 Protein, Human, Recombinant (His) MGC133132,fatty acid binding protein 2,FABPI,I-FABP	Human	E. coli
	Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP family proteins could be used as tissue specific injury marker based on the following characteristics of FABP. The intestinal fatty acid binding protein (I-FABP), or fatty acid-binding protein 2 (FABP2), an intracellular protein expressed only in the intestine, involved in the a...
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His) acetyl-CoA acetyltransferase 2	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc) Pla2g10,Group X secretory phospholipase A2,Phosphatidylcholi...	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li...

重组蛋白

MGAM Protein, Human, Recombinant (aa 960-1853, His)

Cat.No: TMPH-01636

Species: Human

Expression System: Baculovirus Insect Cells

PNLIPRP1 Protein, Canine, Recombinant (His)

Cat.No: TMPH-00491

Species: Canine

Expression System: P. pastoris (Yeast)

PNLIPRP1 Protein, Canine, Recombinant (His & SUMO)

Cat.No: TMPH-00492

Species: Canine

Expression System: E. coli

MGAM Protein, Human, Recombinant (aa 87-954, His)

Cat.No: TMPH-01635

Species: Human

Expression System: Baculovirus Insect Cells

MMUT Protein, Human, Recombinant (His)

Cat.No: TMPH-01678

Species: Human

Expression System: E. coli

KHK Protein, Human, Recombinant (His)

Cat.No: TMPJ-00479

Species: Human

Expression System: HEK293 Cells

FOLR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00150

Species: Human

Expression System: HEK293 Cells

PNLIP Protein, Human, Recombinant (His)

Cat.No: TMPY-03222

Species: Human

Expression System: HEK293 Cells

GSTM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02223

Species: Human

Expression System: E. coli

Aldolase B Protein, Human, Recombinant (GST)

Cat.No: TMPY-02622

Species: Human

Expression System: E. coli

GBA3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01579

Species: Human

Expression System: Baculovirus Insect Cells

ASAH2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00963

Species: Mouse

Expression System: HEK293 Cells

CEL Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03353

Species: Mouse

Expression System: Baculovirus Insect Cells

XPNPEP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01351

Species: Human

Expression System: E. coli

FABP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02051

Species: Human

Expression System: E. coli

ACAT2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04813

Species: Rat

Expression System: E. coli

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02690

Species: Mouse

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T37119	1,2,3-Trioctanoyl-rac-glycerol-13C3 1,2,3-Trioctanoyl-rac-glycerol-13C3
	1,2,3-Trioctanoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2,3-trioctanoyl-rac-glycerol by GC- or LC-MS. 1,2,3-Trioctanoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trioctanoyl-rac-glycerol increases hippocampal levels of the glycolytic metabolites glucose 6-phosphate, fructose 6-phosphate, and β-hydroxybutyrate and the seizure threshold in the 6 Hz psychomo...
T36384	DL-Tyrosine-13C9,15N L-Tyrosine-13C9,15N
	L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...
T71305	Clofibric Acid-d4
	Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal...
T35790	Palmitic acid-1,2,3,4-13C4 Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
TMID-0303	Vitamin A-d4 Retinol-d4
	Vitamin A-d4 是 Vitamin A 的氘代化合物。Vitamin A 的 CAS 号为 68-26-8。Retinol 及其衍生物，在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。膳食维生素 A 来源于植物中发现的多种类胡萝卜素。它富含肝脏、蛋黄和乳制品的脂肪成分。
T69600	Spermidine-d6
	Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µM) inhibits the activity of the human inward-rectifying potassium channel Kir2.3 in a patch-clamp assay. It induces autophagy in HeLa cells when used at a concentration of 100 µM and increases the lifespan of D. melanogaster, yeast, and C. elegans. Spermidine (30 mM in the drinki...
T35789	Palmitic acid-1-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 \|1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791	Palmitic acid-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...

同位素标记化合物

1,2,3-Trioctanoyl-rac-glycerol-13C3

Cat.No: T37119

Synonym: 1,2,3-Trioctanoyl-rac-glycerol-13C3

DL-Tyrosine-13C9,15N

Cat.No: T36384

Synonym: L-Tyrosine-13C9,15N

Clofibric Acid-d4

Cat.No: T71305

Palmitic acid-1,2,3,4-13C4

Cat.No: T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Cat.No: TMID-0303

Synonym: Retinol-d4

Cat.No: T69600

Palmitic acid-1-13C

Cat.No: T35789

Palmitic acid-13C

Cat.No: T35791

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