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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2208 |
Bacitracin Zinc
杆菌肽锌,Bacitracin zinc salt,Zinc bacitracin |
c-Met/HGFR; Antibacterial; Antibiotic | Microbiology/Virology; Tyrosine Kinase/Adaptors |
Bacitracin Zinc 是 C55-异戊二烯焦磷酸酯的去磷酸化干扰物,可抑制 Met-enkephalin 中 Tyr 的裂解,IC50为10 μM。 | |||
T29221 |
(R)-ZINC-3573
ZINC 3573 |
MRGPR | GPCR/G Protein |
(R)-ZINC-3573是一种有效且高选择性的MRGPRX2探针。(R)-ZINC-3573激活人肥大细胞系中的内源性MRGPRX2,诱导细胞脱粒和钙释放。 | |||
T7105 |
Zinc phthalocyanine
酞菁锌,ZnPc |
Others | Others |
Zinc phthalocyanine (ZnPc) 可用于环己烷的光氧化,广泛应用于工业 (催化剂、光导体)和生物医学(光动力疗法、PDT)。 | |||
T13396 |
Zinc Protoporphyrin
Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX |
Apoptosis; Reactive Oxygen Species; Endogenous Metabolite | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB |
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) 是一种具有口服活性的,竞争性血红素加氧酶-1 抑制剂,显著减弱间苯三酚对 H2O2 的保护作用,具有抗癌活性。它用于评估人群铁状态与血红蛋白浓度的组合,也可用作个体孕妇和儿童缺铁的筛查标志物。 | |||
T0502 |
Zinc pyrithione
吡硫锌,OM-1563,吡啶硫酮锌 |
Proton pump; Antibacterial; Antifungal | Membrane transporter/Ion channel; Microbiology/Virology |
Zinc pyrithione (OM-1563) 通过阻断质子泵破坏膜转运,具有抗真菌和细菌作用。 | |||
T35372 |
Zinc acetate
Dicarbomethoxyzinc |
Others | Others |
Zinc acetate (Dicarbomethoxy) 可诱导肠细胞中金属硫蛋白的表达。 | |||
T77665 |
ZINC40099027
ZINC-40099027,ZINC 40099027 |
FAK | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
ZINC40099027 是特异性黏着斑激酶 (FAK) 激活剂,通过激活黏着斑激酶促进持续性阿司匹林相关胃损伤的胃粘膜修复,通过加速FAK激酶结构域的酶活性来激活人黏着斑激酶,激活细胞 FAK 并促进肠上皮伤口闭合。 | |||
T24833 |
ZINC69391
ZINC-69391,ZINC 69391,N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine,CysHHC10 acetate(1408311-03-4 free base) |
Apoptosis; Rho | Apoptosis; Cell Cycle/Checkpoint |
ZINC69391 (CysHHC10 acetate(1408311-03-4 free base)) 是 Rac1 的选择性抑制剂,具有抗增殖和抗转移作用。 ZINC69391 干扰 Rac1 与 Dock180 的相互作用,降低 Rac1-GTP 水平并诱导细胞凋亡。 | |||
T7142 |
Cephalosporin C zinc salt
|
Others | Others |
Cephalosporin C zinc salt 是 SAMHD1的有效抑制剂,IC50值为 1.1 μM。 | |||
T9880 |
ZINC05007751
|
MAPK | MAPK |
ZINC05007751 是 NIMA 相关激酶 NEK6 的有效抑制剂(IC50 = 3.4 μM)。 ZINC05007751 对 NEK1 和 NEK6 具有很强的特异性,对 NEK2、NEK7 和 NEK9 没有显着的活性。 | |||
T81257 |
Rosuvastatin zinc salt
Rosuvastatin zinc |
Others | Others |
Rosuvastatin zinc salt (Rosuvastatin zinc),为Rosuvastatin的含锌盐形态,属于HMG-CoA还原酶抑制剂类药物,常用于动脉粥样硬化的研究领域。 | |||
T13397 |
ZINC03129319
|
Virus Protease | Microbiology/Virology |
ZINC03129319 是有效的登革病毒 NS2B-NS3蛋白酶抑制剂,抑制常数 Ki1和 Ki3分别为 92 μM 和 20 μM。 | |||
T35375 |
Zinc acetate dihydrate
Acetic acid zinc salt dihydrate,Dicarbomethoxyzinc dihydrate |
Others | Others |
Zinc acetate dihydrate (Acetic acid zinc salt dihydrate, Dicarbomethoxyzinc dihydrate) 通过靶向逆转录酶的锌促进杀菌剂凝胶的抗病毒活性。 | |||
T13398 |
ZINC13466751
|
HIF | Angiogenesis; Chromatin/Epigenetic |
ZINC13466751 是有效的 HIF-1α/von Hippel-Lindau 相互作用抑制剂,抑制作用的 IC50为 2.0 µM。 | |||
T61122 |
ZINC12409120
R-4584 |
ERK | MAPK |
ZINC12409120 (R-4584) 是一种具有选择性的 ERK 抑制剂。ZINC12409120 对ERK具有抑制作用,IC50 为 5.0 μM。ZINC12409120 通过干扰 FGF23:α-Klotho 的相互作用而抑制 ERK 活性。 | |||
T4095 |
ZINC00881524
ROCK inhibitor |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
ZINC00881524 (ROCK inhibitor)是一种特异性有效 ROCK 抑制剂。 | |||
T4510 |
Polaprezinc
Zinc L-carnosine,聚普瑞锌,L-肌肽锌 |
Others | Others |
Polaprezinc是一种含有锌和L-carnosine的生物可用螯合物,以其胃肠保护性能、抗溃疡、抗氧化和抗炎效果而闻名。 | |||
T41187 |
(S)-ZINC-3573
|
Others | Others |
(S)-ZINC 3573 is a negative control for (R)-ZINC 3573. (S)-ZINC 3573 displays no activity at MRGPRX2 at concentrations below 100 μM. | |||
T9986 |
(E/Z)-ZINC09659342
|
Rho | Cell Cycle/Checkpoint |
(E/Z)-ZINC09659342 是 Lbc-RhoA 相互作用的抑制剂。 | |||
T35308 |
Zinc decanoate
|
Others | Others |
Zinc decanoate is a biochemical. | |||
T71994 |
Pyrithione Zinc
|
Others | Others |
Pyrithione Zinc is a novel KMD5A inhibitor. | |||
T24952 |
ZINC17167211
ZINC-17167211,ZINC 17167211 |
Others | Others |
ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist. | |||
T24853 |
ZINC05626394
ZINC-05626394,ZINC 05626394 |
Others | Others |
ZINC05626394 is a Cytochrome b5 reductase 3 inhibitor that acts by increasing NO bioavailability. | |||
T24864 |
ZINC08438472
ZINC 08438472,ZINC-08438472 |
Others | Others |
ZINC08438472 is a selective peroxisome proliferator-activated receptors-α agonist. | |||
T65166 |
Zinc-EDTA
|
Others | Others |
Zinc-EDTA 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65166,CAS号为 14025-21-9。 | |||
T21238 |
Antioxidant ZMB
Benzimidazolethiol zinc salt,Zinc mercaptobenzimidazolate,Mercaptobenzimidazole zinc salt,ZMB |
Others | Others |
Antioxidant ZMB, also named Benzimidazolethiol zinc salt,is an antioxidant. | |||
T38344 |
Lalistat 1
ZINC795230 |
Antibacterial | Microbiology/Virology |
Lalistat 1是溶酶体酸性脂肪酶(LAL)抑制剂(IC50 = 68 nM)和流感病毒IgA1蛋白酶的抑制剂。Lalistat 1可用于有关尼曼-皮克C 型疾病的研究。 | |||
T68991 |
ZINC01765622
|
Others | Others |
ZINC01765622 is a novel antagonist for mLST8. | |||
T32746 |
Licorice acid
Licorice acid zinc |
Others | Others |
Licorice acid is used for a zinc supplement in nutrition. | |||
T68986 |
ZINC08383544
|
Others | Others |
ZINC08383544 is a specific pyruvate kinase M2 activator which promotes the formation of PKM2 tetramer. ZINC08383544 effectively blocks PKM2 nuclear translocation, and inhibits the growth of tumor. | |||
T71999 |
ZINC09410451
|
Others | Others |
ZINC09410451 is a potent ebolavirus (EBOV) inhibitor. | |||
T60096 |
EN106
ZINC3888023 |
Others | Others |
EN106 是一种有效的 FEMIB 抑制剂,一种半胱氨酸反应性共价配体。EN106 破坏了对 FEM1B、FNIP1 的关键还原应力底物的识别。 | |||
T37069 |
Pyribencarb
吡菌苯威,ZINC43065336 |
Antifungal | Microbiology/Virology |
Pyribencarb,一种苯甲酰胺类杀菌剂,针对多种植物病原真菌展现出广谱活性。作为细胞色素b的强效Qo抑制剂,Pyribencarb 对灰霉病菌(Botrytis cinerea)和菌核病菌(Sclerotinia sclerotiorum)特别有效。 | |||
T65506 |
Zinc(II) sulfate
|
Others | Others |
Zinc(II) sulfate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65506。 | |||
T64435 |
Zinc carbonate hydroxide
|
Others | Others |
Zinc carbonate hydroxide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64435,CAS号为 5263-02-5。 | |||
T72968 |
ZINC00640089
|
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
ZINC00640089 是一种选择性的脂质运载蛋白-2 (LCN2) 抑制剂。ZINC00640089 对细胞增殖、细胞活力有抑制作用,可减少 SUM149 细胞的 AKT 磷酸化水平。ZINC00640089 可用于研究炎症性乳腺癌 (IBC) 。 | |||
T73604 |
Methyl Green zinc chloride
|
||
Methyl Green zinc chloride为高效荧光染料,主要用于细胞DNA及电泳凝胶染色。该化合物能直接通过显微镜及流式细胞术进行活性测定,其活性峰值位于633至677 nm。储存应避光。 | |||
T12236 |
NMS-859
ZINC169324353 |
Others | Others |
NMS-859 是一种有效的含 valosin 蛋白 (VCP)/p97 的共价抑制剂,在细胞中存在 60 μM 和 1 mM ATP 的情况下,对野生型 VCP 的 IC50 分别为 0.37 μM 和 0.36 μM。 | |||
T60269 |
ZINC194100678
|
PAK | Cytoskeletal Signaling |
ZINC194100678是一种有效的PAK1抑制剂,IC50值为8.37μM 。ZINC194100678 具有较强的抗增殖活性,对MDA-MB-231的IC50值为40.16μM。ZINC194100678可用于癌症的研究。 | |||
T72019 |
ZINC32540717
|
Others | Others |
ZINC32540717 is a potent ebolavirus (EBOV) inhibitor. | |||
T12310 |
ON 146040
ZINC211117138 |
PI3K; Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
ON 146040 是一种有效的 PI3K 异构体抑制剂,对 PI3Kα 和 PI3Kδ 的 IC50 分别为 14 和 20 nM。 | |||
T36123 |
3-Phenyltoxoflavin
ZINC267655,Phenyltoxoflavin |
HSP | Cytoskeletal Signaling; Metabolism |
3-Phenyltoxoflavin (Phenyltoxoflavin) 是一种 HSP90 (Kd = 585 nM) 抑制剂,具有抗癌活性。 | |||
T28509 |
RDR03871
RDR 03871,ZINC20458540,RDR-03871 |
Mdm2 | Apoptosis |
RDR03871是一种 MDM2抑制剂。 | |||
T22835 |
H2L5186303
ZINC33388081 |
LPA Receptor | GPCR/G Protein |
H2L5186303 是一种 LPA2 拮抗剂,可用于哮喘治疗研究。 | |||
T5115 |
Propineb
|
Antibacterial; Antifungal | Microbiology/Virology |
Propineb 具有抗植物真菌疾病的广谱活性,可用于水果和蔬菜病害。 | |||
T19802 |
B-Raf IN 11
|
Raf | MAPK |
B-Raf IN 11 是一种新型选择性抑制剂。 B-Raf 激酶V600E 突变体的DFG-in 构象优于结肠直肠癌中的DFG-out 构象。 | |||
T10674 |
Potassium Channel Activator 1
钾离子通道激活剂1,ZINC34634569 |
Potassium Channel | Membrane transporter/Ion channel |
Potassium Channel Activator 1 可用于治疗多巴胺能系统被破坏的疾病或病症的研究,例如情绪障碍 ADHD、精神分裂症和其他精神病状态。 | |||
T16515 |
PF 750
PF-750,UNII-7756CPP14K,ZINC27647189 |
FAAH | Metabolism; Neuroscience |
PF 750 (ZINC27647189) 是脂肪酸酰胺水解酶的选择性共价抑制剂。 PF 750 的 IC50 在不同的孵育时间从 16.2 到 595 nM 不等。 | |||
T3511 |
PF-1355
PF-06281355,PF 06281355,ZINC205721785 |
Glutathione Peroxidase | Metabolism |
PF-1355 (PF 06281355) 是一种有效的 MPO 抑制剂。PF-1355用于血管炎的研究。 | |||
T11092 |
DPBQ
ZINC1620467,2,3-Diphenylbenzo[g]quinoxaline-5,10-dione |
p53 | Apoptosis |
DPBQ (ZINC1620467) 是一种 p53 的激活剂。DPBQ 以多倍体特异性方式激活并诱导凋亡 (apoptosis),但不会抑制拓扑异构酶或结合 DNA。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0744 |
10-Undecenoic acid zinc salt
Zinc diundec-10-enoate,Zinc 10-undecenoate,Zinc undecylenate,十一烯酸锌 |
Antibiotic; Antifungal | Microbiology/Virology |
10-Undecenoic acid zinc salt (Zinc undecylenate) 是一种天然的或合成的抗真菌脂肪酸, 在乳膏中可局部用于治疗湿疹、真菌感染、癣和其他皮肤病。 锌具有收敛作用。 | |||
T3271 |
Orotic acid zinc
乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate |
Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others |
Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体,从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放,通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大,是尿素循环异常的常规新生儿筛查中的一种测量指标。 | |||
T5812 |
Zinc Phytate
|
Others | Others |
Zinc Phytate 存在于食物中,对人类吸收营养有重要意义。 | |||
T19608 |
Zinc sulfate heptahydrate
|
Others | Others |
Zinc sulfate heptahydrate 是七水合形式的硫酸锌,是一种膳食补充剂,可用于锌缺乏症和预防高危人群的锌缺乏症。 | |||
TN5028 |
Sinensin
ZINC38908691 |
Others | Others |
Sinensin 是一种来自 Cudrania cochinchinensis 的草本植物中的类黄酮。 | |||
T3366 |
Cephalotaxine
ZINC19795976,三尖杉碱,(-)-Cephalotaxine,Cephalotaxlen |
Antiviral; Influenza Virus | Immunology/Inflammation; Microbiology/Virology |
Cephalotaxine (ZINC19795976) 是从头孢紫杉中分离得到的一种生物碱,具有抗白血病和抗病毒活性,如抗 Zika 病毒。 | |||
TN3091 |
5,7-Diacetoxy-8-methoxyflavone
ZINC77031696 |
PDE | Metabolism |
5,7-Diacetoxy-8-methoxyflavone 源自黄芩的根,可抑制 cAMP 磷酸二酯酶。 | |||
TN7200 |
3-chloro-1H-indole
ZINC6117681,3-chloro-1H-indole,3-氯吲哚 |
Others | Others |
3-chloro-1H-indole (ZINC6117681) 是一种海洋来源的天然产物,存在于 Ptychodera flava。 | |||
TN7184 |
5,6-dibromo-1H-indole-3-carbaldehyde
ZINC198368276,5,6-二溴吲哚-3-甲醛 |
Others | Others |
5,6-dibromo-1H-indole-3-carbaldehyde 是一种海洋来源的天然产物,存在于Smenospongia sp.。 | |||
TN1599 |
Eburicoic acid
Eburicoicacid,MFCD00238594,ZINC4655149,齿孔菌酸 |
Antioxidant; TNF; NOS; NO Synthase; CCR; Immunology/Inflammation related | Apoptosis; Immunology/Inflammation; Microbiology/Virology; oxidation-reduction |
Eburicoic acid (ZINC4655149) 具有抗炎和抗氧化活性,从而保护肝脏免受 CCl4 引起的肝损伤,可用于抗肝癌研究。 | |||
TN7189 |
4,6-Dibromoindole
ZINC13450450,4,6-dibromo-1H-indole,4,6-二溴吲哚 |
Others | Others |
4,6-Dibromoindole (ZINC13450450) 是一种海洋来源的天然产物,存在于Glossobalanus sp.。 | |||
TN7174 |
methyl 5-bromo-1H-pyrrole-2-carboxylate
甲基 5-溴-1H-吡咯-2-甲酸酯,ZINC13379818 |
Others | Others |
methyl 5-bromo-1H-pyrrole-2-carboxylate 是一种海洋来源的天然产物,存在于Lissodendoryx sp.。 | |||
T10939L |
L-Cystathionine
L-胱硫醚,Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L- |
Apoptosis; Endogenous Metabolite | Apoptosis; Metabolism |
L-Cystathionine (Cystathionine, L-) 是一种与含硫氨基酸的代谢条件有关的关键非蛋白质氨基酸。L-Cystathionine 可用于有关心血管保护的研究。 | |||
TN7197 |
6-Chloro-2,4-dibromophenol
2,4-dibromo-6-chloro-phenol,2,4-二溴-6-氯苯酚,2,4-dibromo-6-chlorophenol,ZINC397569 |
Others | Others |
6-Chloro-2,4-dibromophenol (2,4-dibromo-6-chlorophenol) 是一种海洋来源的天然产物,存在于Pseudoalteromonas luteoviolacea。 | |||
TN7196 |
5,6-dibromo-1H-indole-3-carboxylic acid
5,6-dibromo-1H-indole-3-carboxylicAcid,5,6-二溴-1H-吲哚-3-羧酸,ZINC4219119 |
Others | Others |
5,6-dibromo-1H-indole-3-carboxylic acid (5,6-dibromo-1H-indole-3-carboxylicAcid) 是一种海洋来源的天然产物,存在于 Smenospongia sp.。 | |||
TN7209 |
3-bromopyrrole-2,5-dione
ZINC13379821,3-溴-1H-吡咯-2,5-二酮,3-Bromo-1H-pyrrole-2,5-dione |
Others | Others |
3-bromopyrrole-2,5-dione (ZINC13379821) 是一种海洋来源的天然产物,存在于 Axinella brevistyla。 | |||
TN7142 |
N-methyl-1H-indole-2-carboxamide
1H-indole-2-carboxylic acid methylamide,ZINC35137534,N-甲基-1H-吲哚-2-酰胺 |
Others | Others |
N-methyl-1H-indole-2-carboxamide (ZINC35137534) 是一种海洋来源的天然产物,存在于 Neosartorya pseudofischeri。 | |||
TN1584 |
Dihydropalmatine
ZINC689644,2,3,9,10-tetramethoxy-6,8-dihydro-5H-isoquinolino[2,1-b]isoquinoline,二氢巴马汀 |
Others | Others |
Dihydropalmatine (2,3,9,10-tetramethoxy-6,8-dihydro-5H-isoquinolino[2,1-b]isoquinoline) 是一种来源于小檗根和茎皮的天然产物。 | |||
TN7177 |
6-Bromoindole-3-carboxylic acid
6-溴吲哚-3-羧酸,ZINC2547985,6-Bromo-1H-indole-3-carboxylic acid |
Others | Others |
6-Bromoindole-3-carboxylic acid (ZINC2547985) 是一种海洋来源的天然产物,存在于Pseudosuberites hyalinus。 | |||
TN1587 |
Dihydroseselin
ZINC302323,8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one,二氢邪蒿内酯 |
Others | Others |
Dihydroseselin (8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one) 是一种源自 Toddalia 根的香豆素。 | |||
TN7136 |
1,7-dimethyl-1H-indole-3-carbaldehyde
1,7-dimethylindole-3-carbaldehyde,ZINC14592128,N,7-Dimethylindole-3-carbaldehyde |
Others | Others |
1,7-dimethyl-1H-indole-3-carbaldehyde (ZINC14592128) 是一种海洋来源的天然产物,存在于 Lyngbya majuscula。 | |||
T10938 |
D-Kynurenine
D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 |
GPR; AhR; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism |
D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。 | |||
TN7207 |
Ethyl6-bromo-1H-indole-3-carboxylate
Ethyl 6-Bromoindole-3-carboxylate,ethyl 6-bromo-3-indolecarboxylate,ZINC13379655,6-溴吲哚-3-甲酸乙酯 |
Others | Others |
Ethyl6-bromo-1H-indole-3-carboxylate (Ethyl 6-Bromoindole-3-carboxylate) 是一种海洋来源的天然产物,存在于 Nocardiopsis sp。 | |||
TN7146 |
2,6-Dibromo-4-(hydroxymethyl)phenol
ZINC2525484,2,6-二溴-4-(羟甲基)苯酚,3,5-dibromo-p-hydroxybenzyl alcohol,3,5-Dibromo-4-Hydroxybenzyl alcohol |
Others | Others |
2,6-Dibromo-4-(hydroxymethyl)phenol (3,5-dibromo-p-hydroxybenzyl alcohol) 是一种海洋来源的天然产物,存在于 Thelepus setosus。 | |||
TN7190 |
3-Bromo-4-Methoxyphenylacetonitrile
3-Bromo-4-methoxybenzyl Cyanide,ZINC2565991,2-(3-bromo-4-methoxyphenyl)acetonitrile,3-溴-4-甲氧基苯乙腈 |
Others | Others |
3-Bromo-4-Methoxyphenylacetonitrile (ZINC2565991) 是一种海洋来源的天然产物,存在于 Aiolochroia crassa。 | |||
TN7147 |
6-Hydroxyisatin
6-Hydroxy-1H-indole-2,3-dione,ZINC14455608,6-hydroxyindoline-2,3-dione,6-羟基靛红,6-hydroxy-2,3-dihydro-1H-indole-2,3-dione |
Others | Others |
6-Hydroxyisatin (ZINC14455608) 是一种海洋来源的天然产物,存在于 Streptomyces sp.。 | |||
TN7138 |
Methyl 5-hydroxy-1H-indole-3-carboxylate
ZINC40836050,5-羟基-1H-吲哚-3-甲酸甲酯,5-hydroxy-1H-indole-3-carboxylic acid methyl ester,Methyl5-hydroxy-1H-indole-3-carboxylate |
Others | Others |
Methyl 5-hydroxy-1H-indole-3-carboxylate (5-hydroxy-1H-indole-3-carboxylic acid methyl ester) 是一种海洋来源的天然产物,存在于Hyrtios erectus。 | |||
TN7198 |
6-Bromoindole-3-acetonitrile
6-溴吲哚-3-乙腈,6-Bromo-1H-indole-3-acetonitrile,ZINC13379652,2-(6-bromo-1H-indol-3-yl)acetonitrile |
Others | Others |
6-Bromoindole-3-acetonitrile (2-(6-bromo-1H-indol-3-yl)acetonitrile) 是一种海洋来源的天然产物,存在于Pseudosuberites hyalinus。 | |||
TN7143 |
1,3-Diphenethylurea
N,N'-Diphenethylurea,1,3-bis(2-phenylethyl)urea,N,N'-Bis(phenethyl)urea,1,3-双(2-苯乙基)脲,ZINC150349,N,N'-bis(2-phenylethyl)urea |
Others | Others |
1,3-Diphenethylurea (N,N'-Bis(phenethyl)urea) 是一种海洋来源的天然产物,存在于 Lissoclinum patella。 | |||
TN1614 |
Episyringaresinol
(+)-epi-syringaresinol,ZINC5665087,(+)-Lirioresinol A,表丁香脂素 |
Others | Others |
Episyringaresinol ((+)-epi-syringaresinol) 是一种从 Kalimeris indica 中分离出来的天然木脂素。 | |||
T2O2667 |
Methyl Oleate
油酸甲酯,oleic acid methyl ester,Methyl cis-9-Octadecenoate,cis-9-Octadecenoic Acid methyl ester |
Others; Antioxidant | Others; oxidation-reduction |
Methyl oleate 是脂肪酸甲酯。它能够显著提高抗氧化能力,但也明显削弱二烷基二硫代磷酸锌的抗磨能力。 | |||
T5530 |
Mithramycin A
Plicamycin |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Mithramycin A (Plicamycin) 是一种dna 结合的抗肿瘤抗生素,选择性特异性蛋白1 (Sp1)抑制剂,通过降低Sp1蛋白抑制多种肿瘤的生长。特异性蛋白1 (Sp1)是一种锌指转录因子,调节多种细胞功能,促进肿瘤进展。 | |||
TN6694 |
5,6-Benzoflavone
β-Naphthoflavone,beta-NF |
Antioxidant | oxidation-reduction |
5,6-Benzoflavone (β-Naphthoflavone) 是芳烃受体的外源配体,可破坏人肝癌 HepG2 细胞中的锌稳态。5,6-Benzoflavone (β-Naphthoflavone) 具有抗炎和抗氧化活性,抑制通过 AKT/Nrf-2/HO-1-NF-kappaB 信号转导轴,抑制 LPS 诱导的炎症,抑制TNF-α诱导的ICAM-1和VCAM-1表达,可用于研究神经退行性疾病。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03117 |
Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)
ZAG,α-2-glycoprotein 1, zinc-binding,Zinc ... |
Human | HEK293 Cells |
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malign... | |||
TMPH-02402 |
Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)
Zinc metalloproteinase,PEP1,PRO A |
Legionella pneumophila | E. coli |
Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease. | |||
TMPH-03401 |
Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Rat, Recombinant (His & Myc)
Azgp1,Zinc-alpha-2-glycoprotein |
Rat | E. coli |
Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.7 kDa and the accession number is Q63678. | |||
TMPH-03580 |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Staphylococcus aureus neutral proteinase,aur,Zinc m... |
Staphylococcus aureus | E. coli |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177. | |||
TMPJ-01376 |
ZNF70 Protein, Human, Recombinant (His)
Zinc Finger Protein N27C7-1,Zinc Finger Pr... |
Human | E. coli |
Zinc Finger Protein 70 (ZNF70) is a member of the krueppel C2H2-type zinc-finger protein family. ZFN70 is localized to the cell nucleus and contains eleven C2H2-type zinc fingers. ZFN70 has sequence-specific DNA binding transcription factor activity, and it may be involved in transcriptional regulation. In addition, ZFN70 has the DNA-binding and metal-binding activity, which can bind zinc ion. | |||
TMPH-02977 |
ZNF346 Protein, Mouse, Recombinant (His & SUMO)
Just another zinc finger protein,Znf346,Zinc |
Mouse | E. coli |
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity. May bind to specific miRNA hairpins. ZNF346 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 48.7 kDa and the accession number is Q9R0B7. | |||
TMPH-01345 |
FIZ1 Protein, Human, Recombinant (His)
Flt3-interacting zinc finger protein 1,FIZ1,Zin... |
Human | E. coli |
May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation. FIZ1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.0 kDa and the accession number is Q96SL8. | |||
TMPH-02318 |
ZBTB32 Protein, Human, Recombinant (His)
ZBTB32,Zinc finger and BTB domain-containing protei... |
Human | E. coli |
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells. ZBTB32 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.5 kDa and the accession number is Q9Y2Y4. | |||
TMPJ-01280 |
ZNF75A Protein, Human, Recombinant (His)
ZNF75A,Zinc Finger Protein 75A |
Human | E. coli |
Zinc Finger Protein 75A (ZNF75A) is a member of krueppel C2H2-type zinc-finger protein family. The human ZNF75 gene is located on Xq26, which has only limited homology (less than 65%) to other ZF genes in the databases. One of these, ZNF75B is a pseudogene mapped to chromosome 12q13. The other two, ZNF75A and ZNF75C, maintain an ORF in the sequenced region, and at least the latter is expressed in the U937 cell line. ZNF75A contains five C2H2-type zinc fingers and one KRAB domain. ZNF75A is a nuc... | |||
TMPJ-01097 |
ZBTB17 Protein, Human, Recombinant (His)
MIZ1,ZNF60,Myc-Interacting Zinc Finger Protein 1,ZN... |
Human | E. coli |
Zinc Finger and BTB Domain-Containing Protein 17 (ZBTB17) belongs to the Kruppel C2H2-type zinc finger protein family. ZBTB17 may function as a housekeeping DNA-binding protein that regulates the expression of specific genes, it has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. ZBTB17 may has growth arrest activity, probably through inhibition of cell cycle progression. ZBTB17 required for early embryonic development during gastrul... | |||
TMPH-02323 |
SLC30A8 Protein, Human, Recombinant (His)
Zinc transporter 8,Proton-coupled zinc ant... |
Human | E. coli |
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q8IWU4. | |||
TMPH-02978 |
IKZF2 Protein, Mouse, Recombinant (His & Myc)
Ikzf2,Zinc finger protein Helios,Ikaros family ... |
Mouse | E. coli |
Associates with Ikaros at centromeric heterochromatin. IKZF2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 66.8 kDa and the accession number is P81183. | |||
TMPH-01956 |
Wiz Protein, Human, Recombinant (His & Myc)
Widely-interspaced zinc finger-containing protein,P... |
Human | E. coli |
Wiz Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-01270 |
ZMYND19 Protein, Human, Recombinant (His)
MCH-R1-Interacting Zinc Finger Protein,Zinc |
Human | E. coli |
Human Zinc Finger MYND Domain-Containing Protein 19 (ZMYND19) is a protein that contains 1 MYND-Type Zinc Finger. ZMYND19 can be expressed by the brain, testis, placenta, heart, liver, skeletal muscle, kidney, and stomach. ZMYND19 interacts with GPR24/MCH-R1. It binds to the C terminus of Melanin-Concentrating Hormone Receptor-1 and the N Termini of α-Tubulin. ZMYND19 may be involved as a regulatory molecule in GPR24/MCH-R1 signaling. | |||
TMPJ-01214 |
ZNF100 Protein, Human, Recombinant (His)
Zinc Finger Protein 100,ZNF100 |
Human | E. coli |
Zinc Finger Protein 100 (ZNF100) is part of the krueppel C2H2-type zinc-finger protein family. ZNF100 contains 12 C2H2-type zinc fingers and 1 KRAB domain. ZNF100 is a DNA-binding protein domain consisting of zinc fingers. Zinc finger protein 100 occurs in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding domain. Zinc finger proteins have also found use in protein engineering due to their modularity and have prospects as components of tools for us... | |||
TMPH-02058 |
SALL4 Protein, Human, Recombinant (His)
Zinc finger protein SALL4,SALL4,Zinc finge... |
Human | Baculovirus Insect Cells |
SALL4 Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPH-02979 |
SLC30A8 Protein, Mouse, Recombinant (His)
Slc30a8,Proton-coupled zinc antiporter SLC30A8,... |
Mouse | E. coli |
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.0 kDa and the accession number is Q8BGG0. | |||
TMPH-01698 |
MORC4 Protein, Human, Recombinant (His & Myc)
MORC4,Zinc finger CW-type domain protein 4,MORC fam... |
Human | E. coli |
Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0. | |||
TMPH-01914 |
PDCD2 Protein, Human, Recombinant (His)
Zinc finger protein Rp-8,Programmed cell death prot... |
Human | E. coli |
PDCD2 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02396 |
Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Z Protein (His)
RING finger protein Z,Z,Zinc-binding protein |
LASV | E. coli |
Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins in... | |||
TMPH-03641 |
TroA Protein, Treponema pallidum, Recombinant (His & Myc)
Zinc-binding protein TroA,troA,Tromp-1 |
Treponema pallidum | E. coli |
Part of an ATP-driven transport system TroABCD for zinc. Substrate-binding protein involved in the transport of zinc across the cytoplasmic membrane. TroA Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.2 kDa and the accession number is P96116. | |||
TMPH-02050 |
RNF114 Protein, Human, Recombinant (GST)
Zinc finger protein 313,RING finger protein 114,RNF... |
Human | E. coli |
RNF114 Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-02321 |
GLI1 Protein, Human, Recombinant (His)
Zinc finger protein GLI1,Glioma-associated oncogene... |
Human | E. coli |
Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling.; Acts as a transcriptional activator, but activates a different set of genes tha... | |||
TMPJ-01263 |
ZBTB9 Protein, Human, Recombinant (His)
ZBTB9,Zinc finger and BTB domain-containing protein... |
Human | E. coli |
Zinc finger and BTB domain-containing protein 9 is a protein-coding gene. ZBTB9 is a 473 amino acids protein that Contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. Diseases associated with ZBTB9 include systemic lupus erythematosus, and lupus erythematosus. Zinc finger and BTB domain-containing protein 9 may be involved in transcriptional regulation. | |||
TMPH-01697 |
MORC3 Protein, Human, Recombinant (His & SUMO)
Zinc finger CW-type coiled-coil domain protein 3,MO... |
Human | E. coli |
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is ... | |||
TMPH-02319 |
ZSCAN1 Protein, Human, Recombinant (His & Myc)
Zinc finger and SCAN domain-containing protein 1,ZS... |
Human | Baculovirus Insect Cells |
May be involved in transcriptional regulation. | |||
TMPJ-00986 |
CTCF Protein, Human, Recombinant
Transcriptional Repressor CTCF,CCCTC-Binding Factor,CTCFL Pa... |
Human | E. coli |
Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or rep... | |||
TMPH-01939 |
LIN28A Protein, Human, Recombinant (His & SUMO)
LIN28A,Protein lin-28 homolog A,Zinc finger CCHC do... |
Human | E. coli |
LIN28A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.7 kDa and the accession number is Q9H9Z2. | |||
TMPH-01000 |
BCL6 Protein, Human, Recombinant
ZNF51,LAZ3,ZBTB27,Zinc finger protein 51,BCL6,BCL-5... |
Human | E. coli |
BCL6 Protein, Human, Recombinant is expressed in E. coli. | |||
TMPH-01940 |
LIN28A Protein, Human, Recombinant (His)
LIN28A,Zinc finger CCHC domain-containing protein 1... |
Human | P. pastoris (Yeast) |
LIN28A Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPH-00999 |
BCL6 Protein, Human, Recombinant (His)
BCL-5,B-cell lymphoma 5 protein,BCL5,Zinc finger an... |
Human | E. coli |
BCL6 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02287 |
ZRANB1 Protein, Human, Recombinant (His & Myc)
TRAF-binding domain-containing protein,Zinc finger ... |
Human | E. coli |
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. ZRANB1 Prot... | |||
TMPH-02322 |
SLC30A10 Protein, Human, Recombinant (His & Myc)
SLC30A10,Zinc transporter 10,Calcium/manganese anti... |
Human | E. coli |
SLC30A10 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.9 kDa and the accession number is Q6XR72. | |||
TMPH-00216 |
SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)
Snake venom metalloproteinase,von Willebrand factor-dependen... |
Bothrops jararaca | E. coli |
Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation. SVMP Protein, Bothrops jararaca, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.0 kDa and the accession number is P22028. | |||
TMPH-02320 |
ZC3H7B Protein, Human, Recombinant (His & Myc)
Rotavirus 'X'-associated non-structural protein,Zinc |
Human | E. coli |
May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop. | |||
TMPH-00672 |
Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)
stcE,Neutral zinc metalloprotease StcE,Metalloprote... |
E. coli | E. coli |
Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves human C1 inhibitor (SERPING1), a regulator of multiple inflammatory pathways, and binds and localizes it to bacterial and host cell surfaces, protecting them from complement-mediated lysis. Therefore, the current model proposes two roles for StcE during infection: it acts first as... | |||
TMPH-01242 |
IKZF1 Protein, Human, Recombinant (Avi & His)
DNA-binding protein Ikaros,Ikaros family zinc finge... |
Human | E. coli |
IKZF1 Protein, Human, Recombinant (Avi & His) is expressed in E. coli expression system with N-6xHis-Avi tag. The predicted molecular weight is 56.8 kDa and the accession number is Q13422. | |||
TMPJ-00721 |
ZBED1 Protein, Human, Recombinant (His)
TRAMP,dREF Homolog,ALTE,DREF,ZBED1,Zinc Finger BED ... |
Human | E. coli |
Zinc Finger BED Domain-Containing Protein 1 (ZBED1) contains one BED-type zinc finger and is found in the cell nucleus. ZBED1 is widely expressed, highly in heart, skeletal muscle, spleen and placenta. The expression of ZBED1 is usually linked to the cell cycle. During the G1/S phase, the expression is increasing. During the S/G2 phage, the expression reaches to the highest, and then decreasing. ZBED1 exists in homodimer forms, which can bind to 5’-TGTCCG[CT]GA[CT]A-3’ DNA elements, that can be ... | |||
TMPJ-00883 |
EGR1 Protein, Human, Recombinant (His)
zinc finger protein 225,NGFI-A,Zif268,Early growth ... |
Human | E. coli |
EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies su... | |||
TMPH-02049 |
ZC3H12A Protein, Human, Recombinant (His)
Regnase-1,ZC3H12A,Zinc finger CCCH domain-containin... |
Human | E. coli |
ZC3H12A Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02640 |
ZC3H12A Protein, Mouse, Recombinant (His & Myc)
Zinc finger CCCH domain-containing protein 12A,Zc3h... |
Mouse | E. coli |
ZC3H12A Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 73.0 kDa and the accession number is Q5D1E7. | |||
TMPH-01484 |
SMYD3 Protein, Human, Recombinant (His & Myc)
Zinc finger MYND domain-containing protein 1,SMYD3,... |
Human | E. coli |
SMYD3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-01179 |
SWSAP1 Protein, Human, Recombinant (His)
SWS1-associated protein 1,SWIM-type zinc finger 7-a... |
Human | E. coli |
SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD51C, RAD51D and XRCC3. It involves in homologous recombination repair. ATPase is preferentially stimulated by single-stranded DNA and is involved in homologous recombination repair (HRR). SWSAP1 has a DNA-binding activity which is independent of its ATPase activity. | |||
TMPH-02324 |
SLC39A6 Protein, Human, Recombinant (His)
Solute carrier family 39 member 6,Zinc transporter ... |
Human | Baculovirus Insect Cells |
May act as a zinc-influx transporter. SLC39A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 35.0 kDa and the accession number is Q13433. | |||
TMPH-01275 |
ZNRF3 Protein, Human, Recombinant (His)
ZNRF3,RING-type E3 ubiquitin transferase ZNRF3,RING finger p... |
Human | HEK293 Cells |
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs ... | |||
TMPH-01930 |
CBFA2T1 Protein, Human, Recombinant (His & Myc)
CDR,ETO,AML1T1,Eight twenty one protein,RUNX1T1,Cyclin-D-rel... |
Human | E. coli |
CBFA2T1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-01274 |
ZNRF3 Protein, Human, Recombinant (His & SUMO)
RING-type E3 ubiquitin transferase ZNRF3,E3 ubiquitin-protei... |
Human | E. coli |
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs ... | |||
TMPJ-00675 |
ZNHIT1 Protein, Human, Recombinant (His)
ZNFN4A1,CGBP1,inc finger HIT domain-containing protein 1,cyc... |
Human | E. coli |
ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at least SRCAP, DMAP, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. ZNHIT1 may play a role in p53-mediated apoptosis induction. | |||
TMPH-01208 |
DEAF1 Protein, Human, Recombinant (His)
SPN,ZMYND5,Suppressin,Zinc finger MYND domain-conta... |
Human | E. coli |
DEAF1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 65.4 kDa and the accession number is O75398. | |||
TMPH-01941 |
PARP12 Protein, Human, Recombinant (His & Myc)
Protein mono-ADP-ribosyltransferase PARP12,PARP12,ADP-ribosy... |
Human | E. coli |
PARP12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
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