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TMPK-01151
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MXRA8 Protein, Human, Recombinant (His)
Asp3,Limitrin,Adipocyte-specific 3,DICAM,Adipocyte-specific ...
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Human
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HEK293 Cells
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Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 36.70 kDa and the accession number is Q9BRK3-1. |
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TMPK-01166
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MXRA8 Protein, Mouse, Recombinant (His)
Asp3,DICAM,Adipocyte-specific protein 3,Adipocyte-specific 3...
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Mouse
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HEK293 Cells
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Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.11 kDa and the accession number is Q9DBV4. |
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TMPY-02219
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Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
NS1 Protein
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H1N1
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E. coli
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The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As... |
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TMPH-03297
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LGALS3BP Protein, Rat, Recombinant (His)
Protein 90K,Mac-2-binding protein,Galectin-3-binding protein...
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Rat
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E. coli
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Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
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TMPH-01362
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LGALS3BP Protein, Human, Recombinant (His)
LGALS3BP,Lectin galactoside-binding soluble 3-binding protei...
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Human
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E. coli
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Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. LGALS3BP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.4 kDa and the accession number is Q08380. |
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TMPK-00255
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CD209/DC-SIGN Protein, Human, Recombinant (His)
CD209,DC-SIGN,CLEC4L,CD209 molecule,DC-SIGN1,MGC129965,CDSIG...
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Human
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HEK293 Cells
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C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as SARS, SARS-CoV-2, bacteria, fungi and parasites. Pathogens exploit CD209 family proteins to promote infection and evade the immune recognition system. |
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TMPY-06802
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HSV 2 (strain 333) Glycoprotein D/gD Protein (His)
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HSV2
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HEK293 Cells
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Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for significant neurological morbidity, perhaps more than any other virus. Herpes simplex virus type 2–associated neurological disease may result from primary infection or reactivation of latent HSV-2. Common severe infections include encephalitis, meningitis, neonatal herpes, and, in immun... |
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TMPY-02841
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Fragilis/IFITM3 Protein, Human, Recombinant (mFc)
DSPA2b,1-8U,interferon induced transmembrane protein 3,IP15
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Human
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HEK293 Cells
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Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon-inducible transmembrane protein family members, IFITM1, 2, and 3, are IEGs required for inhibition of influenza A virus, dengue virus, and West Nile virus replication in vitro. IFITM3 is an IFN-induced anti... |
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TMPH-01308
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GSPT1 Protein, Human, Recombinant (His & Myc)
GSPT1,Eukaryotic peptide chain release factor GTP-binding su...
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Human
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P. pastoris (Yeast)
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Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. GSPT... |
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TMPJ-00133
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MBL2 Protein, Mouse, Recombinant
Mannose binding lectin (C),MBL-2,Mannose-binding protein C,M...
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Mouse
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HEK293 Cells
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Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phas... |
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TMPH-01247
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POLR3K Protein, Human, Recombinant (His)
RNA polymerase III subunit C11,POLR3K,RNA polymerase III 12....
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Human
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Baculovirus Insect Cells
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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase I... |
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TMPH-01235
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APOBEC3A Protein, Human, Recombinant (His & SUMO)
A3A,APOBEC3A,DNA dC->dU-editing enzyme APOBEC-3A,Phorbolin-1
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Human
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E. coli
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DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a rol... |
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TMPJ-01310
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TRIM5 Protein, Human, Recombinant (His)
RNF88,Tripartite motif-containing protein 5,RING finger prot...
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Human
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E. coli
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Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of actio... |
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TMPH-02212
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TLR8 Protein, Human, Recombinant (His)
TLR8,Toll-like receptor 8
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Human
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P. pastoris (Yeast)
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Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of RNA degradation products specific to microorganisms that are initially processed by RNASET2. Recognizes GU-rich single-stranded RNA (GU-rich RNA) derived from SARS-CoV-2, SARS-CoV-1 and HIV-1 viruses. Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-con... |
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TMPJ-01049
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CYPA Protein, Human, Recombinant
Rotamase A,Peptidyl-prolyl cis-trans isomerase A,PPIase A,PP...
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Human
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E. coli
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Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressi... |
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TMPJ-01355
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SEMA4G Protein, Human, Recombinant (His)
Semaphorin-4G,SEMA4G,KIAA1619
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Human
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HEK293 Cells
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Semaphorin-4G is belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and ve... |
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TMPJ-01206
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Sting Protein, Human, Recombinant (Sumo & His)
TMEM173,Mediator of IRF3 activation,Stimulator of interferon...
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Human
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E. coli
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Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2,... |
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TMPY-02909
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ASGR2 Protein, Human, Recombinant (His)
HBXBP,ASGPR2,HL-2,asialoglycoprotein receptor 2,ASGP-R2,CLEC...
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Human
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HEK293 Cells
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ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is ... |
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TMPY-05693
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SARS-CoV-2 Methyltransferase/ME Protein (His)
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SARS-CoV-2
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E. coli
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Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate immunity during viral infection. Nonstructural protein 16 (NSP16) / viral 2'O-methyltransferase (2'O-MTase) is highly conserved. The conserved 2'O-MTase activity is important for CoV pathogenesis and NSP16 is a conserved universal target for rapid live attenuated vaccine design ... |
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TMPJ-00201
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CLEC10A Protein, Human, Recombinant (His)
HML,C-Type Lectin Domain Family 10 Member A,CLECSF14,CLEC10A...
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Human
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HEK293 Cells
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C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. It constitute a unique class of C-type lectins b... |
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TMPH-03758
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TSG101 Protein, Human, Recombinant (His & Myc & SUMO)
Tumor susceptibility gene 101 protein,ESCRT-I complex subuni...
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Human
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E. coli
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Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an intera... |
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TMPJ-00809
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CFH Protein, Human, Recombinant (His)
CFH,Complement factor H
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Human
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HEK293 Cells
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Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessi... |
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TMPJ-00323
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Nectin-2 Protein, Mouse, Recombinant (hFc)
Herpes Virus Entry Mediator B,PVRL2,Poliovirus Receptor-Rela...
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Mouse
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HEK293 Cells
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CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju... |
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TMPJ-01425
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SARS-CoV-2 NSP1 Protein (His)
SARS-CoV 2 nsp1,SARS-CoV 2 Leader protein
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SARS-CoV-2
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E. coli
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The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close associa... |
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TMPH-01246
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POLR3A Protein, Human, Recombinant (His)
RNA polymerase III subunit C160,RNA polymerase III 155 kDa s...
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Human
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E. coli
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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft ... |
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TMPH-02236
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TMPRSS2 Protein, Human, Recombinant (E. coli, His)
Transmembrane protease serine 2,TMPRSS2,Serine protease 10
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Human
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E. coli
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Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.... |
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TMPH-02237
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TMPRSS2 Protein, Human, Recombinant (His & Myc)
Serine protease 10,Transmembrane protease serine 2,TMPRSS2
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Human
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HEK293 Cells
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Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.... |
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TMPY-01855
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Serpin A10 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,...
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Mouse
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HEK293 Cells
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Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPINA1 / Serpin-A1 inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because ... |
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