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Search Results for " monophosphate "

Targets Recommended: Others

120

抑制剂 & 化合物

37

天然产物

2

化合物库

20

重组蛋白

10

同位素标记化合物

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Cat. No.	Product Name
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L7700	神经再生化合物库		524 compounds
	524 种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

神经再生化合物库

Cat.No: L7700

Compounds: 524

Cat. No.	Product Name	Target	Signaling Pathways
T21195	AICAR monophosphate Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide	Others	Others
	AICAR monophosphate (Aica ribonucleotide) 是一种具有抗肿瘤活性的嘌呤前体，可用于 2 型糖尿病的研究。
T37636	2'-Deoxyguanosine 5'-monophosphate disodium 5′-dGMP disodium	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) 是一种核酸三磷酸鸟苷（GTP）衍生物，可作为可氧化靶标，可用于和其他化合物组成多元配合物。
T65979	Adenosine 5'-monophosphate disodium salt Adenosine Phosphate Disodium,5‘-AMP-NA2	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) 是一种参与 ATP 代谢的嘌呤核苷酸，用于研究 ATP 对细胞和生物体的影响。Adenosine 5'-monophosphate disodium salt 已被证明具有多种生化和生理作用,它可以促进细胞代谢、基因表达和蛋白质合成。
T1129	Benfotiamine Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺	Others	Others
	Benfotiamine (S-Benzoylthiamine O-monophosphate) 是维生素 B1 的类似物，其吸收率和生物利用度比维生素B1高，具有直接抗氧化能力，可防止DNA 损伤。它常用作糖尿病并发症的食品补充剂。
T21329	Gemcitabine monophosphate disodium salt Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP	Others	Others
	R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro.
T68656	Brivudine monophosphate	Others	Others
	Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator...
T39334	Remdesivir nucleoside monophosphate	Others	Others
	Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV.
T71036	Adefovir monophosphate	Others	Others
	Adefovir monophosphate is an antiviral acyclic nucleoside phosphonate (ANP) analog with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). It is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) that works by blocking reverse transcriptase for the treatment of hepatitis B. Adefovir dipivoxil is not effective against HIV-1.
T33099	Lyxoflavin 5'-monophosphate	Others	Others
	Lyxoflavin 5'-monophosphate binds to flavodoxin.
T37877	Ribavirin 5'-monophosphate (lithium salt)	Others	Others
	Ribavirin 5'-monophosphate (lithium salt)对 IMP 脱氢酶（将 IMP 转化为 XMP）具体直接抑制作用
T37375	Uridine-3'-monophosphate (sodium salt)	Others	Others
	Uridine-3'-monophosphate is a nucleoside used in the biochemical synthesis of ribothymidine-3'-phosphate. It has been used as a bioavailable source of uridine in research studies designed to enhance learning and memory.
T35652	2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)	Others	Others
	2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
T35571	Adenosine 3’-monophosphate (sodium salt hydrate)	Others	Others
	Adenosine 3’-monophosphate is a nucleotide and metabolite formedviahydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.1It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2Breceptor antagonist MRS1754.2Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine .
T37789	Riboflavin 5'-monophosphate (sodium salt hydrate)	Others	Others
	Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways. FMN also binds the FMN riboswitch (RFN element) on RNA to alter gene regulation. FMN is a substrate of FMN phosphohydrolases and is used to study their function.
T36300	Uridine-5’-monophosphate (sodium salt hydrate)	Others	Others
	Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements. 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002)
T22825	Guanosine-2'(3')-monophosphate disodium salt	Others	Others
	Guanosine-2'(3')-monophosphate disodium salt 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T22825。
T4187	Gemcitabine monophosphate sodium salt hydrate	Others; DNA; DNA/RNA Synthesis; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Gemcitabine monophosphate sodium salt hydrate 是Gemcitabine 的单磷酸盐衍生物。
T5166L	Leniolisib phosphate Leniolisib monophosphate	Others	Others
	Leniolisib phosphate is an effective PI3K inhibitor.
T22869	Inosine-5'-monophosphate (sodium salt hydrate)	Others	Others
	substrate of IMP dehydrogenase (IMPDH)
T12162	N6-Methyladenosine 5'-monophosphate disodium salt	Others	Others
	N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator(Ka of 22 µM).
T60709	Acyclovir monophosphate	Others	Others
	Acyclovir monophosphate 是抗单纯疱疹病毒 (HSV)剂，并且具有抗肿瘤活性。Acyclovir monophosphate 通过抑制病毒 DNA 聚合酶从而阻断 DNA 合成，同时能终止病毒 DNA 的链延伸。
T15339	Foscarbidopa Carbidopa 4′-monophosphate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T85002	Cytidine 3'-monophosphate 3'-CMP	Others	Others
	Cytidine 3'-monophosphate, a ribonucleotide, results from the hydrolysis of cytidine 2’,3’-cyclic monophosphate via RNase—a process that cytidine 3'-monophosphate itself inhibits. Additionally, it can be dephosphorylated to cytidine by 3’-nucleotidase.
T84932	Cytarabine 5′-monophosphate ara-CMP	Others	Others
	Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg.
T75377	Thymolphthalein monophosphate disodium hydrate
	Thymolphthalein monophosphate disodium hydrate 是用于测定酸性及碱性磷酸酶显色底物。反应过程中释放的百里酚酞可增加介质pH，促使颜色产生并终止水解作用，特别适合于血清中前列腺磷酸酶的特异性检测。
T77247	D-myo-Inositol 4-monophosphate	Others	Others
	D-myo-Inositol 4-mono-phos-phate 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。
T39890	8-Bromo-AMP 8-Bromoadenosine 5'-monophosphate,8-Bromo-AMP,8-Bromoadenylicacid	Others	Others
	8-Bromo-AMP, also known as 8-Bromoadenosine 5'-monophosphate, is a membrane permeable cAMP analogue. It enhances cardiac recovery from ischemia and reperfusion by elevating ATP, ADP, and total adenine nucleotide concentrations.
TNU1647	Adenosine 5’-monophosphate triethylammonium salt	Others	Others
	Adenosine 5’-monophosphate triethylammonium salt 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1647。
T67245	Inosine-5'-monophosphate Disodium Salt heptahydrate	Others	Others
	Inosine-5'-monophosphate Disodium Salt heptahydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67245，CAS号为 849725-39-9。
T83472	1,N6-Ethenoadenosine 5'-monophosphate sodium 1,N6-ε-AMP sodium,1,N6-Etheno-AMP sodium
	1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium 是一种针对adenosine 5'-monophosphate系统的荧光探针，具备低浓度检测能力。该化合物拥有较长的激发波长（250-300 nm）和415 nm的发射波长。
T75198	2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethylammonium	Others	Others
	2’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium) 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要针对惰性淋巴系统的恶性肿瘤。其作用机制涉及抑制 DNA 合成和诱导细胞凋亡(apoptosis)。
T75195	2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethylammonium	Others	Others
	2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) 是嘌呤核苷类似物，主要应用于靶向惰性淋巴系统恶性肿瘤的抗肿瘤活性研究中。其抗癌机制包括抑制 DNA 合成和诱导细胞凋亡 (apoptosis)，显示出广泛的抗肿瘤效果。
TNU1275	2’-O-Methyladenosine 5’-monophosphate triethyl ammonium	Others	Others
	Nucleoside Phosphates; Nucleoside Derivateives - 2’-Modified nucleosides
T75196	2’-O-Methyladenosine 5’-monophosphate triethyl ammonium	Others	Others
	2’-O-Methyladenosine 5’-monophosphate triethyl ammonium 是一种腺嘌呤核苷类似物。腺苷类似物大多可作为平滑肌血管扩张剂，也被证明能够抑制癌症进展。它的热门产品有 Adenosine phosphate，Acadesine ，Clofarabine ，Fludarabine phosphate 和 Vidarabine 。
T75197	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium	Others	Others
	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium 是一种嘌呤核苷类似物，拥有广泛的抗肿瘤活性，特别是对惰性淋巴系统的恶性肿瘤。其抗癌作用机制主要通过抑制 DNA 合成及诱导细胞凋亡（apoptosis）实现。
TNU1259	2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium	Others	Others
	Nucleoside Phosphates;
TNU1276	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium	Others	Others
	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1276。
T75188	2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium	Others	Others
	2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium 为嘌呤核苷类似物，主要拥有广泛的抗肿瘤活性，并针对惰性淋巴系统恶性肿瘤。其抗癌作用机制涉及抑制 DNA 合成和诱导细胞凋亡(apoptosis)等过程。
TNU1274	2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium	Others	Others
	Nucleoside Phosphates; Nucleoside Derivateives - 2’-Modified nucleosides; Fluoro-modified nucleosides
TNU1277	2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium	Others	Others
	2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1277。
T7447	Adefovir	HBV; Reverse Transcriptase; Telomerase	DNA Damage/DNA Repair; Microbiology/Virology
	Adefovir 是一种单磷酸腺苷类似物抗病毒剂，在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。
T33762	Fosifloxuridine nafalbenamide NUC-3373,NUC3373,NUC 3373	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Fosifloxuridine nafalbenamide (NUC 3373) 是一种胸腺嘧啶合酶抑制剂，属于嘧啶核苷酸类似物，具有抗癌活性。它能诱发宿主免疫反应，有潜力增强免疫治疗。
TNU1630	2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule)	Others	Others
	2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1630。
T35421	2'-O-Succinyl-cAMP	Others	Others
	2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2
T20048	Vidarabine phosphate	Antiviral	Immunology/Inflammation
	Vidarabine phosphate 是一种单磷酸腺苷类似物。它是 VIDARABINE 的单磷酸酯。它还具有抗病毒和可能的抗肿瘤特性。
T8735	Sulbactum Sodium 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸	Others	Others
	Sulbactum Sodium (5'-CDP) 由胞苷一磷酸 (CMP) 或尿苷一磷酸 (UMP) 通过磷酸基团的转移在尿苷酸激酶 (UMPK) 酶的催化下合成。
T3444	Merimepodib 美泊地布,VX-497,VI-21497	Dehydrogenase; Antiviral; HCV Protease; HBV	Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Merimepodib (VX-497) 是一种新型非竞争性肌苷一磷酸脱氢酶抑制剂，具有广谱抗病毒活性。
T29069	Uprifosbuvir MK3682,IDX21437,IDX-21437,IDX 21437,MK 3682,MK-3682	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Uprifosbuvir (MK-3682)是一种丙型肝炎病毒 NS5B RNA 聚合酶的尿苷核苷单磷酸前药抑制剂，具有抗病毒活性，用于研究慢性丙型肝炎病毒。
T0467	Sildenafil citrate UK-92480 citrate,西地那非柠檬酸盐,枸橼酸西地那非	Apoptosis; PDE; Autophagy	Apoptosis; Autophagy; Metabolism
	Sildenafil citrate (UK-92480 citrate) 是一种磷酸二酯酶 5 抑制剂，IC50为 5.22 nM。
T0245	RS 61443 RS61443,吗替麦考酚酯,Mycophenolate mofetil,TM-MMF	Dehydrogenase	Metabolism
	RS 61443 (Mycophenolate mofetil) 是一种免疫抑制剂，一种非竞争性、选择性和可逆的肌苷一磷酸脱氢酶 (IMPDH) 抑制剂。

化合物

AICAR monophosphate

Cat.No: T21195

Synonym: Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide

Target: Others

2'-Deoxyguanosine 5'-monophosphate disodium

Cat.No: T37636

Synonym: 5′-dGMP disodium

Target: Endogenous Metabolite

Adenosine 5'-monophosphate disodium salt

Cat.No: T65979

Synonym: Adenosine Phosphate Disodium,5‘-AMP-NA2

Target: Nucleoside Antimetabolite/Analog

Cat.No: T1129

Synonym: Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺

Target: Others

Gemcitabine monophosphate disodium salt

Cat.No: T21329

Synonym: Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP

Target: Others

Brivudine monophosphate

Cat.No: T68656

Target: Others

Remdesivir nucleoside monophosphate

Cat.No: T39334

Target: Others

Adefovir monophosphate

Cat.No: T71036

Target: Others

Lyxoflavin 5'-monophosphate

Cat.No: T33099

Target: Others

Ribavirin 5'-monophosphate (lithium salt)

Cat.No: T37877

Target: Others

Uridine-3'-monophosphate (sodium salt)

Cat.No: T37375

Target: Others

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

Cat.No: T35652

Target: Others

Adenosine 3’-monophosphate (sodium salt hydrate)

Cat.No: T35571

Target: Others

Riboflavin 5'-monophosphate (sodium salt hydrate)

Cat.No: T37789

Target: Others

Uridine-5’-monophosphate (sodium salt hydrate)

Cat.No: T36300

Target: Others

Guanosine-2'(3')-monophosphate disodium salt

Cat.No: T22825

Target: Others

Gemcitabine monophosphate sodium salt hydrate

Cat.No: T4187

Target: Others, DNA, DNA/RNA Synthesis, Autophagy

Leniolisib phosphate

Cat.No: T5166L

Synonym: Leniolisib monophosphate

Target: Others

Inosine-5'-monophosphate (sodium salt hydrate)

Cat.No: T22869

Target: Others

N6-Methyladenosine 5'-monophosphate disodium salt

Cat.No: T12162

Target: Others

Acyclovir monophosphate

Cat.No: T60709

Target: Others

Cat.No: T15339

Synonym: Carbidopa 4′-monophosphate

Target: Dopamine Receptor

Cytidine 3'-monophosphate

Cat.No: T85002

Synonym: 3'-CMP

Target: Others

Cytarabine 5′-monophosphate

Cat.No: T84932

Synonym: ara-CMP

Target: Others

Thymolphthalein monophosphate disodium hydrate

Cat.No: T75377

D-myo-Inositol 4-monophosphate

Cat.No: T77247

Target: Others

Cat.No: T39890

Synonym: 8-Bromoadenosine 5'-monophosphate,8-Bromo-AMP,8-Bromoadenylicacid

Target: Others

Adenosine 5’-monophosphate triethylammonium salt

Cat.No: TNU1647

Target: Others

Inosine-5'-monophosphate Disodium Salt heptahydrate

Cat.No: T67245

Target: Others

1,N6-Ethenoadenosine 5'-monophosphate sodium

Cat.No: T83472

Synonym: 1,N6-ε-AMP sodium,1,N6-Etheno-AMP sodium

2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethylammonium

Cat.No: T75198

Target: Others

2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethylammonium

Cat.No: T75195

Target: Others

2’-O-Methyladenosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1275

Target: Others

2’-O-Methyladenosine 5’-monophosphate triethyl ammonium

Cat.No: T75196

Target: Others

2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium

Cat.No: T75197

Target: Others

2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium

Cat.No: TNU1259

Target: Others

2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1276

Target: Others

2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium

Cat.No: T75188

Target: Others

2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1274

Target: Others

2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1277

Target: Others

Cat.No: T7447

Target: HBV, Reverse Transcriptase, Telomerase

Fosifloxuridine nafalbenamide

Cat.No: T33762

Synonym: NUC-3373,NUC3373,NUC 3373

Target: DNA/RNA Synthesis

2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule)

Cat.No: TNU1630

Target: Others

2'-O-Succinyl-cAMP

Cat.No: T35421

Target: Others

Vidarabine phosphate

Cat.No: T20048

Target: Antiviral

Sulbactum Sodium

Cat.No: T8735

Synonym: 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸

Target: Others

Cat.No: T3444

Synonym: 美泊地布,VX-497,VI-21497

Target: Dehydrogenase, Antiviral, HCV Protease, HBV

Cat.No: T29069

Synonym: MK3682,IDX21437,IDX-21437,IDX 21437,MK 3682,MK-3682

Target: HCV Protease

Sildenafil citrate

Cat.No: T0467

Synonym: UK-92480 citrate,西地那非柠檬酸盐,枸橼酸西地那非

Target: Apoptosis, PDE, Autophagy

Cat.No: T0245

Synonym: RS61443,吗替麦考酚酯,Mycophenolate mofetil,TM-MMF

Target: Dehydrogenase

Cat. No.	Product Name	Target	Signaling Pathways
T4925	Thiamine monophosphate chloride (dihydrate) Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride	Others; Endogenous Metabolite	Metabolism; Others
	Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) 是内源性代谢产物的一种。
T2133	Adenosine monophosphate 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate	Endogenous Metabolite; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Adenosine monophosphate (AMP) 是一种嘌呤核糖核苷5'-单磷酸腺苷，是信号转导和调节能量稳态的关键细胞代谢物。它具有EC 3.1.3.11(果糖-二磷酸酶)抑制剂、EC 3.1.3.1(碱性磷酸酶)抑制剂和腺苷A1受体激动剂的作用。
T4730	Thymidine-5'-monophosphate disodium salt 胸苷酸二钠,Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT	Others; Endogenous Metabolite	Metabolism; Others
	Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) 是内源性代谢产物的一种。
T4737	2'-Deoxyadenosine-5'-monophosphate D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸，是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
TMA2440	Uridine 5'-monophosphate disodium salt 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate	Others	Others
	Uridine 5'-monophosphate disodium salt (Disodium UMP) 是合成 RNA 的一种重要成分。
T4735	2'-Deoxyuridine 5'-monophosphate disodium 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt 能够被双底物酶胸苷酸合酶(TS) 还原甲基化为 dTMP (2'-deoxythymidine 5'-monophosphate)。其中 dTMP 是 DNA 合成所需的核苷酸。
TMO2752	Cytidine 5'-monophosphate 5'-Cytidylic acid,5'-CMP,胞苷酸,Cytidylic Acid	Others; Endogenous Metabolite	Metabolism; Others
	Cytidine 5'-monophosphate (5'-Cytidylic acid) 是一种核苷酸，是组成 RNA 的基本单位之一。它由核碱基胞嘧啶，戊糖核糖和磷酸基团组成。
T0853L	Adenosine 5'-monophosphate monohydrate 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid	AMPK; Adenosine Receptor; HSV	Chromatin/Epigenetic; GPCR/G Protein; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Adenosine 5'-monophosphate monohydrate (5'-AMP) 是一种核苷酸，用作 RNA 中的单体。它是一个腺苷 A1受体激动剂，对HSV-1和HSV-2具有显著的抗病毒活性。
T5073	Inosine 5'-monophosphate disodium salt hydrate Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt) 或肌苷酸是次黄嘌呤的核糖核苷酸，是嘌呤合成过程中形成的第一个核苷酸。
T4718	Uridine 5'-monophosphate Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid	Others; Endogenous Metabolite	Metabolism; Others
	Uridine 5'-monophosphate (Uridylic acid) 是一种单磷酸盐形式的尿嘧啶核苷酸，能够由从头途径或体内核苷酸和核酸的降解产物获得，是哺乳动物乳中的主要核苷酸类似物。
T40370	2′-Deoxyadenosine 5′-monophosphate disodium	Endogenous Metabolite	Metabolism
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T8186	Xanthosine 5'-monophosphate sodium salt XMP,黄苷-5′-单磷酸钠,L-XMP Sodium	Others	Others
	Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) 是嘌呤代谢的一种中间体。它可用于研究遗传密码，核酸结构以及 DNA，RNA 和蛋白质合成。
T39626	Orotidine 5′-monophosphate Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate	Others	Others
	Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase.
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD Monosodium-GMP,cGMP sodium salt,鸟苷-3',5'-环磷酸一钠盐,Cyclic GMP	PKA	Tyrosine Kinase/Adaptors
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) 也称为 cGMP，是一种细胞调节剂，被描述为第二信使。它的水平随着各种激素的增加而增加，包括乙酰胆碱、胰岛素和催产素。 cGMP 激活蛋白激酶 G(PKG) 并调节离子通道电导，信号传导影响多种过程，包括平滑肌松弛和增殖、光转导和能量稳态。
T4685	INOSINIC ACID Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P	Endogenous Metabolite	Metabolism
	Inosinic acid (IMP) 是内源性代谢产物。
T4731	2'-Deoxycytidine-5'-monophosphoric acid dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) 被用作尿苷单磷酸(UMP)或胞苷单磷酸(CMP)激酶的底物，形成 dCDP，在磷酸化成 dCTP 后支持 DNA 的生物合成。
T20054	Adenosine-2'-monophosphate 2'-Adenylic acid	Others	Others
	2'-Adenylic acid is an agent of bioactive chemical.
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
TCO2745	Cyclic AMP Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate	Others; Endogenous Metabolite	Metabolism; Others
	Cyclic AMP (cAMP)(Adenosine 3',5'-cyclophosphate) 是有丝分裂信使，可以促进 G1期到 S 期的细胞周期进程。
T75676	Orotidine 5′-monophosphate trisodium	Others	Others
	Orotidine 5'-monophosphate trisodium 是一种嘧啶核苷酸。Orotidine 5'-monophosphate trisodium 是通过从头合成途径合成的，用于在大量微生物中合成 DNA，包括 M. tuberculosis、S. cerevisiae、S. typhimurium 和 P. falciparum 等等。乳清酸磷酸核糖基转移酶 (OPRT) 以磷酸核糖焦磷酸 (PRPP) 和乳清酸 (OA) 作为底物催化合成 Orotidine 5'-monophosphate trisodium[1]
T19346	5'-Guanylic acid 鸟苷酸,5'-guanosine monophosphate,5'-GMP	Endogenous Metabolite	Metabolism
	5'-Guanylic acid (5'-guanosine monophosphate) 与几种代谢紊乱有关，包括腺苷脱氨酶缺乏症、 aica-核糖体途径、腺嘌呤磷酸转移酶缺乏症 (aprt) 以及 2-羟基葡糖酸盐途径。
T2185	L-Ascorbic acid 2-phosphate trisodium L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐	Reactive Oxygen Species; c-Met/HGFR; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) 是长效的维生素 C 衍生物，能够刺激胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate 提高成骨细胞分化过程中 hASC 中的碱性磷酸酶活性和 runx2A 的表达，因此，能够促进人脂肪干细胞的成骨分化。
T1335	Mycophenolic acid 霉酚酸,Mycophenolate,RS-61443	Apoptosis; Dehydrogenase; Endogenous Metabolite; Antibacterial; Antibiotic; UGT; Antifungal	Apoptosis; Metabolism; Microbiology/Virology
	Mycophenolic acid (Mycophenolate) 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂，EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂，具有抗血管生成和抗肿瘤作用。
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T7327	7-Methoxyisoflavone	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	7-Methoxyisoflavone 是单磷酸腺苷活化蛋白激酶 (AMPK) 的激活剂，是异黄酮衍生物。
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others; Antioxidant	Others; oxidation-reduction
	(+)-pinoresinol-β-D-glucoside; (+)-pinor 是连翘中主要的活性呋喃类木脂素。它显示出抗氧化、降血压和环磷酸腺苷 (cAMP) 磷酸二酯酶抑制活性。
T5084	Xanthosine dihydrate 黄苷二水合物	Others; Endogenous Metabolite	Metabolism; Others
	Xanthosine dihydrate 是衍生自黄嘌呤和核糖的核苷，能够提高牛和山羊的乳腺干细胞数量和产奶量。
T6293	Mycophenolate Mofetil TM-MMF,吗替麦考酚酯,RS 61443	Apoptosis; Dehydrogenase; Drug Metabolite	Apoptosis; Metabolism
	Mycophenolate Mofetil (TM-MMF) 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成，显示出选择性淋巴细胞抗增殖作用。
PDK0014	3-Methylxanthine	Endogenous Metabolite	Metabolism
	3-Methylxanthine 是一种黄嘌呤衍生物和环磷酸鸟苷（GMP）抑制剂，在豚鼠分离的气管肌肉中测得其IC50值为 920 μM。
T5067	Flavin adenine dinucleotide disodium salt Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2	Others; Endogenous Metabolite	Metabolism; Others
	Flavin adenine dinucleotide disodium salt (FAD sodium salt) 是一种辅酶，作用是促进细胞氧化还原反应中黄素酶的电子转移。
T8047	Menthyl acetate 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate	Others	Others
	Menthyl acetate 是一种可有效增强 5-氨基乙酰丙酸 (ALA) 皮肤渗透的 L-薄荷醇衍生物。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一，抑制溴脱氧尿苷 (Brdu) 的生物效应。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
TN3013	4,5-Dimethoxycanthin-6-one Methylnigakinone	P450; Antibacterial; PDE	Metabolism; Microbiology/Virology
	4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂（IC50 ： 1.7 μM, Ki ： 2.6 μM），对环磷酸腺苷（cAMP）磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性，对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。
TN1841	Kushenol A 苦参新醇 A,Leachianone E	cAMP	GPCR/G Protein
	Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushenol A and kushenol C exhibit inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).
TN4433	Licoarylcoumarin	cAMP; HIV Protease; Antifection	GPCR/G Protein; Microbiology/Virology; Proteases/Proteasome
	Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase.
TN5147	Tilifodiolide	IL Receptor; TNF; GABA Receptor	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.
T35770	Cylindrospermopsin	Others	Others
	Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...

天然产物

Thiamine monophosphate chloride (dihydrate)

Cat.No: T4925

Synonym: Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride

Target: Others, Endogenous Metabolite

Adenosine monophosphate

Cat.No: T2133

Synonym: 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate

Target: Endogenous Metabolite, AMPK

Thymidine-5'-monophosphate disodium salt

Cat.No: T4730

Synonym: 胸苷酸二钠,Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT

Target: Others, Endogenous Metabolite

2'-Deoxyadenosine-5'-monophosphate

Cat.No: T4737

Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Target: Others, Endogenous Metabolite

Uridine 5'-monophosphate disodium salt

Cat.No: TMA2440

Synonym: 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate

Target: Others

2'-Deoxyuridine 5'-monophosphate disodium

Cat.No: T4735

Synonym: 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt

Target: Others, Endogenous Metabolite

Cytidine 5'-monophosphate

Cat.No: TMO2752

Synonym: 5'-Cytidylic acid,5'-CMP,胞苷酸,Cytidylic Acid

Target: Others, Endogenous Metabolite

Adenosine 5'-monophosphate monohydrate

Cat.No: T0853L

Synonym: 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid

Target: AMPK, Adenosine Receptor, HSV

Inosine 5'-monophosphate disodium salt hydrate

Cat.No: T5073

Synonym: Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate

Target: Others, Endogenous Metabolite

Uridine 5'-monophosphate

Cat.No: T4718

Synonym: Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid

Target: Others, Endogenous Metabolite

2′-Deoxyadenosine 5′-monophosphate disodium

Cat.No: T40370

Target: Endogenous Metabolite

Xanthosine 5'-monophosphate sodium salt

Cat.No: T8186

Synonym: XMP,黄苷-5′-单磷酸钠,L-XMP Sodium

Target: Others

Orotidine 5′-monophosphate

Cat.No: T39626

Synonym: Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate

Target: Others

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

Cat.No: T5065

Synonym: Monosodium-GMP,cGMP sodium salt,鸟苷-3',5'-环磷酸一钠盐,Cyclic GMP

Target: PKA

Cat.No: T4685

Synonym: Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P

Target: Endogenous Metabolite

2'-Deoxycytidine-5'-monophosphoric acid

Cat.No: T4731

Synonym: dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate

Target: Others, Endogenous Metabolite

Adenosine-2'-monophosphate

Cat.No: T20054

Synonym: 2'-Adenylic acid

Target: Others

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

Cat.No: TCO2745

Synonym: Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate

Target: Others, Endogenous Metabolite

Orotidine 5′-monophosphate trisodium

Cat.No: T75676

Target: Others

5'-Guanylic acid

Cat.No: T19346

Synonym: 鸟苷酸,5'-guanosine monophosphate,5'-GMP

Target: Endogenous Metabolite

L-Ascorbic acid 2-phosphate trisodium

Cat.No: T2185

Synonym: L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐

Target: Reactive Oxygen Species, c-Met/HGFR, Endogenous Metabolite

Mycophenolic acid

Cat.No: T1335

Synonym: 霉酚酸,Mycophenolate,RS-61443

Target: Apoptosis, Dehydrogenase, Endogenous Metabolite, Antibacterial, Antibiotic, UGT, Antifungal

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

7-Methoxyisoflavone

Cat.No: T7327

Target: AMPK

Pinoresinol 4-O-β-D-glucopyranoside

Cat.No: T4S0792

Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside

Target: Others, Antioxidant

Xanthosine dihydrate

Cat.No: T5084

Synonym: 黄苷二水合物

Target: Others, Endogenous Metabolite

Mycophenolate Mofetil

Cat.No: T6293

Synonym: TM-MMF,吗替麦考酚酯,RS 61443

Target: Apoptosis, Dehydrogenase, Drug Metabolite

3-Methylxanthine

Cat.No: PDK0014

Target: Endogenous Metabolite

Flavin adenine dinucleotide disodium salt

Cat.No: T5067

Synonym: Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2

Target: Others, Endogenous Metabolite

Menthyl acetate

Cat.No: T8047

Synonym: 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate

Target: Others

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

4,5-Dimethoxycanthin-6-one

Cat.No: TN3013

Synonym: Methylnigakinone

Target: P450, Antibacterial, PDE

Cat.No: TN1841

Synonym: 苦参新醇 A,Leachianone E

Target: cAMP

Licoarylcoumarin

Cat.No: TN4433

Target: cAMP, HIV Protease, Antifection

Cat.No: TN5147

Target: IL Receptor, TNF, GABA Receptor

Cylindrospermopsin

Cat.No: T35770

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03617	GMPR Protein, Human, Recombinant (His) GMPR1,guanosine monophosphate reductase	Human	E. coli
	GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
TMPH-02964	UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) Cmpk1,UMP-CMP kinase,Nucleoside-diphosphate kinase,Uridine <...	Mouse	E. coli
	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9DBP5.
TMPH-01525	CMAHP Protein, Human, Recombinant (His & Myc) CMAHP,Inactive cytidine monophosphate-N-acetylneura...	Human	E. coli
	Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates. However, it may play a role in Wnt signaling.
TMPH-03503	Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) ATP-AMP transphosphorylase,AK,Adenylate monophosphate	Shigella flexneri	E. coli
	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q83M40.
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cytidine monophosphate	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi...
TMPH-00603	Cytidylate kinase Protein, E. coli, Recombinant (His & SUMO) Cytidine monophosphate kinase,CMP kinase,ycaF,Cytid...	E. coli	E. coli
	ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.
TMPH-02388	pyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO) Orotate phosphoribosyltransferase,pyrE	Laribacter hongkongensis	E. coli
	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). pyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.9 kDa and the accession number is C1D6F5.
TMPK-00853	ENPP1 Protein, Human, Recombinant (N-His) PDNP1,NPP1,NPPase,PCA1ARHR2,PCA1,M6S1,Ly-41 Antigen,ENPP1,E-...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPK-00781	ENPP1 Protein, Mouse, Recombinant (His) ENPP1,PC1,PCA1ARHR2,PCA1,NPP1,M6S1NPP1,PDNP1,NPPS,Ly-41 Anti...	Mouse	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 95.99 kDa and the accession number is P06802-1.
TMPK-00854	ENPP1 Protein, Human, Recombinant (C-His) M6S1,E-NPP 1,PCA1,PDNP1,ENPP1,NPPase,NPPS,M6S1NPP1,PCA1ARHR2...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPK-00852	ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated E-NPP 1,NPPase,PC1,NPP1,PCA1,ENPP1,Ly-41 Antigen,PCA1ARHR2,M...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 98.29 kDa and the accession number is P22413.
TMPJ-01262	UPRT Protein, Human, Recombinant (His) UPRT,UPP,FUR1,Uracil phosphoribosyltransferase homolog	Human	E. coli
	UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
TMPH-00590	GlmU Protein, E. coli, Recombinant (His & Myc) glmU,Bifunctional protein GlmU	E. coli	E. coli
	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
TMPH-00673	NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) NAD-capped RNA hydrolase NudC,nudC,NADH pyrophosphatase	E. coli	E. coli
	mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. NADH pyrophosphatase Protein, E. coli O157:H7, Recombina...
TMPJ-00660	IMPase2 Protein, Human, Recombinant (His) Inositol-1(or 4)-Monophosphatase 2,IMPA2,IMP 2,IMPase 2,Inos...	Human	E. coli
	Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphat...
TMPJ-00905	DTYMK Protein, Human, Recombinant (His) DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TYMK	Human	HEK293 Cells
	Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ...
TMPJ-01308	ITPase Protein, Human, Recombinant (His) Nucleoside-Triphosphate Diphosphatase,Nucleoside-Triphosphat...	Human	E. coli
	Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation...
TMPJ-01200	IMPA3 Protein, Mouse, Recombinant (His) Inositol monophosphatase 3,Impad1	Mouse	HEK293 Cells
	IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an ...
TMPY-02394	IMPA1 Protein, Human, Recombinant (His) IMPA,inositol(myo)-1(or 4)-monophosphatase 1,IMP	Human	E. coli
	IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Ad...
TMPY-02977	PDE1C Protein, Human, Recombinant (His & GST) hCam-3,phosphodiesterase 1C, calmodulin-dependent 70kDa,cam-...	Human	Baculovirus Insect Cells
	PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a s...

重组蛋白

GMPR Protein, Human, Recombinant (His)

Cat.No: TMPY-03617

Species: Human

Expression System: E. coli

UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02964

Species: Mouse

Expression System: E. coli

CMAHP Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01525

Species: Human

Expression System: E. coli

Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03503

Species: Shigella flexneri

Expression System: E. coli

UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04480

Species: Human

Expression System: Baculovirus Insect Cells

Cytidylate kinase Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00603

Species: E. coli

Expression System: E. coli

pyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO)

Cat.No: TMPH-02388

Species: Laribacter hongkongensis

Expression System: E. coli

ENPP1 Protein, Human, Recombinant (N-His)

Cat.No: TMPK-00853

Species: Human

Expression System: HEK293 Cells

ENPP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00781

Species: Mouse

Expression System: HEK293 Cells

ENPP1 Protein, Human, Recombinant (C-His)

Cat.No: TMPK-00854

Species: Human

Expression System: HEK293 Cells

ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00852

Species: Human

Expression System: HEK293 Cells

UPRT Protein, Human, Recombinant (His)

Cat.No: TMPJ-01262

Species: Human

Expression System: E. coli

GlmU Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00590

Species: E. coli

Expression System: E. coli

NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)

Cat.No: TMPH-00673

Species: E. coli

Expression System: E. coli

IMPase2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00660

Species: Human

Expression System: E. coli

DTYMK Protein, Human, Recombinant (His)

Cat.No: TMPJ-00905

Species: Human

Expression System: HEK293 Cells

ITPase Protein, Human, Recombinant (His)

Cat.No: TMPJ-01308

Species: Human

Expression System: E. coli

IMPA3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01200

Species: Mouse

Expression System: HEK293 Cells

IMPA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02394

Species: Human

Expression System: E. coli

PDE1C Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02977

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0086	Mycophenolate Mofetil-d4
	Mycophenolate Mofetil-d4 是 Mycophenolate Mofetil 的氘代化合物。Mycophenolate Mofetil 的 CAS 号为 128794-94-5。Mycophenolate mofetil 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成，显示出选择性淋巴细胞抗增殖作用。
TMIJ-0087	Mycophenolic acid-13C-d3
	Mycophenolic acid-13C-d3 是 Mycophenolic acid 的 13C 和氘代化合物。Mycophenolic acid 的 CAS 号为 24280-93-1。Mycophenolic acid 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂，EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂，具有抗血管生成和抗肿瘤作用。
TMIH-0524	Sofosbuvir-13C-d3
	Sofosbuvir-13C-d3 是 Sofosbuvir 的 13C 和氘代化合物。Sofosbuvir 的 CAS 号为 1190307-88-0。Sofosbuvir 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂，用作治疗慢性丙型肝炎的抗病毒剂。
TMID-0037	Tadalafil-d3
	Tadalafil-d3 是 Tadalafil 的氘代化合物。Tadalafil 的 CAS 号为 171596-29-5。Tadalafil 是一种PDE5抑制剂，IC50为 1.8 nM。
TMIJ-0114	Vardenafil-d5
	Vardenafil-d5 是 Vardenafil 的氘代化合物。Vardenafil 的 CAS 号为 224785-90-4。Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。
TMID-0209	Tadalafil-13C-d3
	Tadalafil-13C-d3 是 Tadalafil 的 13C 和氘代化合物。Tadalafil 的 CAS 号为 171596-29-5。Tadalafil 是一种PDE5抑制剂，IC50为 1.8 nM。
TMIJ-0274	Sulindac-d3
	Sulindac-d3 是 Sulindac 的氘代化合物。Sulindac 的 CAS 号为 38194-50-2。Sulindac 是一种非甾体类抗炎剂，可抑制COX-2的活性，也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药，具有潜在的抗肿瘤活性。
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
TMID-0233	Salbutamol-d9
	Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
TMIH-0512	Salbutamol-d3
	Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。

同位素标记化合物

Mycophenolate Mofetil-d4

Cat.No: TMID-0086

Mycophenolic acid-13C-d3

Cat.No: TMIJ-0087

Sofosbuvir-13C-d3

Cat.No: TMIH-0524

Cat.No: TMID-0037

Cat.No: TMIJ-0114

Tadalafil-13C-d3

Cat.No: TMID-0209

Cat.No: TMIJ-0274

Capecitabine-d11

Cat.No: TMID-0242

Cat.No: TMID-0233

Cat.No: TMIH-0512

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