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Search Results for " immunophilin "

Targets Recommended: Others

3

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9820	GPI-1485 GM1485	Others	Others
	GPI-1485 (GM1485) 是一种免疫抑制的特异性亲免蛋白配体，可促进中风后的神经功能改善和神经再生。
T11451	GPI-1046 1-(1,2-二氧代-3,3-二甲基戊基)-L脯氨酸-(3-吡啶基)-丙酯	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	GPI-1046 是一种无抗生素作用的亲免素配体，部分通过上调 PFC 和 NAc 核心中的谷氨酸转运蛋白 1 来减少乙醇摄入。
T13734	ILS-920	Others	Others
	ILS-920 is a Rapamycin analog characterized by diminished immunosuppressive effects but remarkable neuroprotective properties. It exhibits selective binding affinity towards the immunophilin FKBP52 as well as the β1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 displays a notable 200-fold preference for FKBP52 over FKBP12.

化合物

Cat.No: T9820

Synonym: GM1485

Target: Others

Cat.No: T11451

Synonym: 1-(1,2-二氧代-3,3-二甲基戊基)-L脯氨酸-(3-吡啶基)-丙酯

Target: Others, HIV Protease

Cat.No: T13734

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01076	FKBP4 Protein, Human, Recombinant (His) FKBP4,HSP-binding immunophilin,immunophilin	Human	E. coli
	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
TMPJ-01068	FKBP25/FKBP3 Protein, Human, Recombinant (His) 25 kDa FKBP,FKBP-3,Peptidyl-prolyl cis-trans isomerase FKBP3...	Human	E. coli
	FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a...
TMPJ-00919	FKBP2 Protein, Human, Recombinant (His) also named 13 kDa FK506-binding protein,FK506-binding protei...	Human	HEK293 Cells
	Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 an...

重组蛋白

FKBP4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01076

Species: Human

Expression System: E. coli

FKBP25/FKBP3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01068

Species: Human

Expression System: E. coli

FKBP2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00919

Species: Human

Expression System: HEK293 Cells

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