94
42
3
32
3
Cat. No. | Product Name | ||
---|---|---|---|
L1720 | 核苷类化合物库 | 334 compounds | |
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发; | |||
L1700 | 抗病毒库 | 1040 compounds | |
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选; | |||
L9300 | 大环化合物库 | 210 compounds | |
210 种活性已知的大环化合物,用于高通量、高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76515 |
Herpes virus inhibitor 1
|
||
Herpes virus inhibitor 1 是一种抑制疱疹病毒的化合物,能破坏疱疹病毒的核糖核苷酸还原酶四级结构,从而抑制病毒复制。 | |||
T76517 |
Herpes virus inhibitor 2
|
||
Herpes virus inhibitor 2 为一种疱疹病毒抑制剂,专门破坏疱疹病毒的核糖核苷酸还原酶四级结构,从而抑制病毒复制。 | |||
T3045 |
Salubrinal
|
Apoptosis; Phosphatase; PERK; Autophagy; HSV | Apoptosis; Autophagy; Metabolism; Microbiology/Virology |
Salubrinal 是一种磷酸酶抑制剂 ,对真核翻译起始因子 2 亚基 (eIF2α) 发挥作用。它作为双特异性磷酸酶 2 抑制剂,抑制抗胶原蛋白抗体诱导的关节炎。它具有抗HSV-1病毒的活性,并抑制由HSV-1蛋白 ICP34.5 介导的eIF2α的去磷酸化。 | |||
T15394 |
Glyceryl monocaprate
2,3-Dihydroxypropyl decanoate,一癸酸甘油酯,DECANOIN,Monocaprin |
Antibacterial; HSV | Microbiology/Virology |
Glyceryl monocaprate (2,3-Dihydroxypropyl decanoate) 对单纯疱疹病毒具有抑制作用,有潜力治疗唇疱疹。它是一种癸酸的1-单甘油酯,可抗革兰氏阳性细菌感染。 | |||
T6593 |
ML324
|
Histone Demethylase; Others; HSV | Chromatin/Epigenetic; Microbiology/Virology; Others |
ML324 是 jumonji 组蛋白去甲基化酶的特异性抑制剂,IC50值为920 nM。 | |||
T2504 |
Pritelivir
普瑞利韦,BAY 57-1293,AIC316 |
DNA/RNA Synthesis; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Pritelivir (BAY 57-1293) 是一种病毒解旋酶-引物酶复合物抑制剂,有抗病毒活性。它对 HSV-1 和 HSV-2 具有活性,IC50值为 20 nM。 | |||
T1848 |
Dynasore
Dynamin Inhibitor I |
Dynamin; Virus Protease; Autophagy; HSV | Autophagy; Cytoskeletal Signaling; Microbiology/Virology |
Dynasore (Dynamin Inhibitor I) 是一种可渗透细胞的化学物质,可逆且非竞争性地抑制 dynamin 1/2 的 GTPase 活性。 它还抑制线粒体动力蛋白 Drp1,对其他小 GTPase 没有影响。 | |||
T4226 |
Amenamevir
ASP2151,阿莫奈韦 |
DNA/RNA Synthesis; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Amenamevir (ASP2151) 是一种新型解旋酶引发酶抑制剂,对水痘带状疱疹病毒和 1 型和 2 型单纯疱疹病毒具有活性,EC50值为 14 ng/mL。 | |||
T16911 |
Sorivudine
BV-araU,索立夫定 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Sorivudine (BV-araU) 是口服有效的,嘧啶核苷抗代谢药物。它的抗病毒活性来自某些 DNA 病毒中存在的特定胸苷激酶选择性转化为核苷酸,从而反过来会干扰病毒 DNA 合成。 | |||
T4051 |
LDC4297
LDC044297 |
CDK; HSV | Cell Cycle/Checkpoint; Microbiology/Virology |
LDC4297 (LDC044297)是 CDK7的一种高效选择性抑制剂,IC50值为0.13 nM。 | |||
T0355 |
Valpromide
Depamide,Valpramide,丙戊酰胺,Dipropylacetamide,2-propylpentanamide |
Epoxide Hydrolase; HSV | Metabolism; Microbiology/Virology |
Valpromide (Dipropylacetamide) 是丙戊酸的羧酰胺衍生物,用于治疗癫痫和一些情感障碍。 | |||
T0688 |
Ganciclovir
BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine |
Nucleoside Antimetabolite/Analog; Others; Antibiotic; Antifection; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Ganciclovir (2'-Nor-2'-deoxyguanosine) 是核苷类似物和口服抗病毒药物,对CMV 具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。 | |||
T22337 |
Ganciclovir sodium
RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium,更昔洛韦钠 |
Nucleoside Antimetabolite/Analog; Others; Antifection; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Ganciclovir sodium (Cytovene IV sodium) 是核苷类似物和口服抗病毒药物,具有抗病毒活性,尤其是针对巨细胞病毒和单纯疱疹病毒 1 型。 | |||
T15280 |
Fiacitabine
非西他滨,FOAC,FIAC,NSC 382097 |
HSV | Microbiology/Virology |
Fiacitabine (NSC-382097) 是单纯疱疹病毒 (HSV) DNA 复制的选择性抑制剂,对 HSV1和 HSV2的 IC50分别为2.5 nM 和12.6 nM。 | |||
T1454 |
Acyclovir
Aciclovir,Acycloguanosine,阿昔洛韦 |
Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic; HSV | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Acyclovir (Aciclovir) 是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM),HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。 | |||
T1087 |
Valacyclovir hydrochloride
Valaciclovir hydrochloride,盐酸伐昔洛韦,盐酸万乃洛韦,Valaciclovir HCl |
DNA/RNA Synthesis; Antibiotic; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Valacyclovir hydrochloride (Valaciclovir hydrochloride) 是一种口服有效的抗病毒药物,能抑制疱疹 B,单纯疱疹和带状疱疹。它抑制 HSV-1W,IC50为2.9 μg/ml。它是 Aciclovir 的前药。 | |||
T6787 |
BIO-acetoxime
BIA,GSK-3 Inhibitor X |
Apoptosis; GSK-3; HSV | Apoptosis; Microbiology/Virology; PI3K/Akt/mTOR signaling; Stem Cells |
BIO-acetoxime (GSK-3 Inhibitor X) 是一种 GSK3α/β 抑制剂,IC50值均为 10 nM,具有抗惊厥和抗感染作用。 | |||
T6244 |
Cidofovir
HPMPC,GS 0504,西多福韦,(S)-HPMPC |
Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。 | |||
T8972 |
FIT-039
|
Others; DNA/RNA Synthesis; CDK; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
FIT-039 是一种选择性和 ATP 竞争性的口服活性 CDK9 抑制剂,对CKD9/cyclin T1的IC50为 5.8 μM。它抑制HSV-1(IC50为 0.69 μM),HSV-2,人腺病毒和人CMV 的复制。它可抑制耐药性HSV 和其他 DNA 病毒,是有前途的抗病毒药物。 | |||
T1646 |
Famciclovir
泛昔洛韦,BRL 42810 |
DNA/RNA Synthesis; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Famciclovir (BRL 42810) 是一种单纯疱疹病毒核苷类似物 DNA 聚合酶抑制剂。 | |||
T6073 |
OG-L002
|
Histone Demethylase; Monoamine Oxidase; HSV | Chromatin/Epigenetic; Microbiology/Virology; Neuroscience |
OG-L002 是一种高度选择性的 LSD1有效抑制剂,IC50为 0.02 μM。它抑制HSV IE 基因的表达,还是单胺氧化酶抑制剂,对 MAO-A 和 MAO-B 的IC50分别为 1.38 μM 和 0.72 μM。 | |||
TQ0095 |
Brincidofovir
CMX001,HDP-CDV |
Others; Antiviral; HSV | Immunology/Inflammation; Microbiology/Virology; Others |
Brincidofovir (HDP-CDV) 是 Cidofovir 的一种具有口服活性的亲脂性形式的前体药物,是一种口服长效的抗病毒药物,有广泛的抗 DNA 病毒活性。 | |||
T1643 |
Penciclovir
喷昔洛韦,BRL 39123,VSA 671 |
HCV Protease; Antifection; HSV | Microbiology/Virology; Proteases/Proteasome |
Penciclovir (BRL 39123) 是一种疱疹病毒核苷类似物 DNA 聚合酶抑制剂。它作用于HSV1 和 2,IC50分别为 0.04-1.8 μg/mL 和 0.06-4.4 μg/mL。 | |||
T1109 |
(Z)-Capsaicin
Zucapsaicin,Civamide,cis-Capsaicin,珠卡赛辛,(Z)-辣椒素 |
TRP/TRPV Channel; HSV | Membrane transporter/Ion channel; Microbiology/Virology |
(Z)-Capsaicin (Zucapsaicin) 是天然辣椒素的合成顺式异构体,用于治疗膝骨关节炎。它是一种可口服的 TRPV1激动剂,可研究神经性疼痛。 | |||
T8736 |
Cidofovir dihydrate
HPMPC,(S)-HPMPC,GS 0504,西多福韦二水合物 |
Others | Others |
Cidofovir dihydrate (HPMPC) 是注射型巨细胞病毒 DNA 聚合酶抑制剂,通过选择性抑制病毒 DNA 聚合酶来抑制 CMV 复制,从而阻止病毒复制和转录。 | |||
T1428 |
Trifluridine
曲氟尿苷,NSC 529182,Trifluorothymidine,5-Trifluorothymidine,NSC 75520,曲氟胸苷,Viroptic,Trifluridina |
Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Trifluridine (NSC-75520) 是一种氟化胸苷类似物,具有潜在的抗肿瘤活性,还具有抗病毒活性。它掺入 DNA 并抑制胸苷酸合酶,从而抑制 DNA 合成、抑制蛋白质合成和细胞凋亡。 | |||
T12908 |
SIBA
5'-Deoxy-5'-isobutylthioadenosine,5'-Isobutylthioadenosine,5ˊ-异丁硫基-5ˊ-脱氧腺苷 |
Nucleoside Antimetabolite/Analog; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
SIBA (5'-Deoxy-5'-isobutylthioadenosine) 是 SAH 的合成类似物,可作为 S-腺苷甲硫氨酸介导的甲基转移的抑制剂。它干扰多种酶活性,可逆地阻断单纯疱疹病毒 1 型病毒的繁殖。 | |||
T0134 |
Imiquimod
咪喹莫特,R 837,IMQ,S-26308 |
SARS-CoV; TLR; Autophagy; HSV | Autophagy; Immunology/Inflammation; Microbiology/Virology |
Imiquimod (R 837) 是一种免疫反应修饰剂,可作为 toll 样受体7 激动剂。它有抗病毒和抗肿瘤作用,可研究外生殖器、肛周疣、癌症和 COVID-19。 | |||
T0929 |
Docusate sodium
Aerosol OT,多库脂钠,Dioctyl sulfosuccinate sodium salt,Bis(2-ethylhexyl) sulfosuccinate sodium salt,Constonate |
Opioid Receptor; HSV | Endocrinology/Hormones; GPCR/G Protein; Microbiology/Virology; Neuroscience |
Docusate sodium (Aerosol OT) 是一种口服的非处方泻药和大便软化剂,可用于研究便秘。 | |||
T22419 |
S-Methylisothiourea sulfate
(S)-Methylisothiourea sulfate,S-甲基异硫脲硫酸盐,S-甲基异硫脲半硫酸盐 |
NOS; NO Synthase; HSV | Immunology/Inflammation; Microbiology/Virology |
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) 是一种选择性 iNOS 抑制剂,在感染性休克的啮齿动物模型中发挥有益作用。 | |||
T0964 |
Floxuridine
氟尿苷,5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 |
Apoptosis; Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis; Antibacterial; HSV | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Floxuridine (FUDR) 是一种嘧啶类似物,也是一种抗肿瘤代谢物。它抑制胸苷酸合成酶,导致 DNA 合成中断和细胞毒性。它是一种可诱导细胞凋亡的金黄色葡萄球菌感染抑制剂 ,具有抗HSV 和CMV 病毒的作用。 | |||
T80691 |
β-Herpesvirus protease-IN-1
|
Virus Protease | Microbiology/Virology |
β-Herpesvirus protease-IN-1 (compound 19)为一种针对β-herpesvirus蛋白酶的抑制剂,其对HCMVPro的IC50值为2.5 μM,而对HHV6Pro的IC50值则为0.33 μM。 | |||
T0718 |
Brivudine
Bromovinyldeoxyuridine,BVDU,溴夫定 |
Others; HSV | Microbiology/Virology; Others |
Brivudine (BVDU) 是胸苷类似物,有抗病毒活性,用于早期急性带状疱疹的研究。 | |||
T20436 |
DHQ
2,3-dihydroxy-quinoxalin,2,3-二羟基喹喔啉 |
ATPase | Membrane transporter/Ion channel |
DHQ (2,3-dihydroxy-quinoxalin) 是单纯疱疹病毒胸苷激酶的 ATPase 活性诱导剂。 | |||
T67800 |
GR-95168
|
Antifection | Microbiology/Virology |
GR-95168 ((+)-C-BVDU) 是一种抗病毒化合物,可用于研究1型和2型单纯疱疹病毒感染。 | |||
T26987 |
CF-1743
CF1743 |
HSV | Microbiology/Virology |
CF-1743 是一种抗水痘带状疱疹病毒核苷,可抑制 VZV 复制。 CF-1743可用于水痘和带状疱疹感染的研究。 | |||
T1675 |
Adefovir dipivoxil
Hepsera,GS 0840,阿德福韦酯,Preveon |
Others; HBV; Reverse Transcriptase | Microbiology/Virology; Others |
Adefovir dipivoxil (GS 0840) 是一种腺苷类似物,是核苷逆转录酶抑制剂 Adefovir 的口服前药,具有抗乙型肝炎病毒、疱疹病毒和人类免疫缺陷病毒的活性。 | |||
T7447 |
Adefovir
|
HBV; Reverse Transcriptase; Telomerase | DNA Damage/DNA Repair; Microbiology/Virology |
Adefovir 是一种单磷酸腺苷类似物抗病毒剂,在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。 | |||
T50031 |
Virstatin
|
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Virstatin是一种新型抗病毒药物,是一种有效的病毒复制抑制剂,已被证明对多种病毒有效,包括单纯疱疹病毒(HSV)、人类免疫缺陷病毒(HIV)和流感病毒等。 | |||
T4374 |
Edoxudine
依度尿苷,Aedurid,EUDR,Epoxudine,乙去氧尿啶 |
Antiviral; Antibacterial | Immunology/Inflammation; Microbiology/Virology |
Edoxudine (Epoxudine) 是胸苷的类似物,是一种抗病毒药物,对单纯疱疹病毒有效。 | |||
T74809 |
STING agonist-30
|
STING; Antifection | Immunology/Inflammation; Microbiology/Virology |
STING agonist-30 是一种高效的 STING 激动剂,能激发STING依赖的免疫激活。STING agonist-30 对包括HSV(单纯疱疹病毒)、轮状病毒及SARS-CoV-2(严重急性呼吸系统综合症冠状病毒2)在内的多种病毒显示出广谱抑制效果。 | |||
T60272 |
Isatin-β-thiosemicarbazone
IBT |
HSV | Microbiology/Virology |
Isatin-β-thiosemicarbazone 是一种有效的单纯疱疹病毒 (HSV) 抑制剂。Isatin-β-thiosemicarbazone 在对 HSV-1 和 HSV-2 都具有抑制作用,表现出抗病毒活性。Isatin-β-thiosemicarbazone 是一种有效的抗痘病毒剂 (anti-poxvirus)可用用于治疗猴痘病毒、正痘病毒和牛痘病毒。 | |||
T11449L |
Golotimod
Gamma-D-glutamyl-L-tryptophan,SCV 07 |
Antibiotic | Microbiology/Virology |
Golotimod (SCV 07) 是一种具有抗菌活性的二肽,具有免疫调节活性,能显著提高抗结核治疗的疗效,诱导胸腺和脾脏细胞增殖,调节巨噬细胞功能,抑制 STAT3 信号传导。Golotimod 可用于研究复发性生殖器单纯疱疹病毒 2 (HSV-2)感染和口腔黏膜炎。 | |||
T35113 |
WAY 150138
WAY150138,WAY-150138 |
Others | Others |
WAY 150138 inhibits the herpes simplex virus. | |||
T29628 |
Acyclovir mixture with hydrocortisone
Xerese,ME 609,ME609,ME-609,Lipsovir |
Others | Others |
Acyclovir mixture with hydrocortisone is used for Herpes simplex labialis. | |||
T30475 |
Bismuth camphocarbonate
Bi-Valeas,Solmuth,Cardyl,Rectobismutina,Angimuth |
Others | Others |
Bismuth camphocarbonate is used for herpes zoster. | |||
T33854 |
P-4010
P 4010,P4010 |
Others | Others |
P-4010 is effective against herpes simplex. | |||
T27963 |
Lysine Orotate
|
Others | Others |
Lysine Orotate is an inhibitor of viral replication, especially useful to treat the Herpes family of viruses which includes Herpes Simplex 1 and 2 , CMV, EBV and Varicella. | |||
T26402 |
A 1110U
A-1110U,A1110U |
Others | Others |
A 1110U is an inactivator of herpes simplex virus ribonucloetide reductases. | |||
T64299 |
Valacyclovir hydrochloride hydrate
|
Others | Others |
Valacyclovir hydrochloride hydrate 是一种有效的抗病毒剂,是一种前药,在体内可快速转化为阿昔洛韦。Valacyclovir hydrochloride hydrate 能够用于配制治疗眼部疱疹的眼部插入物。Valacyclovir hydrochloride hydrate 能够用于单纯疱疹、带状疱疹和乙型疱疹的治疗。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6523 |
Guanosine
鸟苷,DL-Guanosine,Vernine,Guanozin |
Endogenous Metabolite; HSV | Metabolism; Microbiology/Virology |
Guanosine (DL-Guanosine) 是由鸟嘌呤与核糖环组成的一种核苷,两者之间由 β-N9-配糖键相连,具有抗HSV 的活性。 | |||
TN1788 |
Isookanin
|
Amylase | Metabolism |
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。 | |||
T3342 |
Xanthohumol
|
Apoptosis; Others; Influenza Virus; COX; Acyltransferase; HSV | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; Others |
Xanthohumol 是从啤酒花中分离到的黄酮类化合物,可抑制 COX-1 和 COX-2 活性,具有抗肿瘤,抗血管生成的作用,还具有抗多种病毒的活性。 | |||
T5712 |
zerumbone
花薑酮,球姜酮 |
Antioxidant; HSV | Microbiology/Virology; oxidation-reduction |
Zerumbone 是从Zingiber zerumbetSmith 的根茎中分离的一种单环倍半萜烯,可有效抑制Epstein-Barr 病毒的激活,IC50为 0.14 mM,具有抗癌、抗炎、抗氧化和抗增殖的作用。 | |||
T7983 |
Isoborneol
DL-Isoborneol,异冰片,异龙脑 |
HSV | Microbiology/Virology |
Isoborneol (DL-Isoborneol) 是存在于许多药用植物精油中的一种单萜醇,具有抗氧化和抗病毒特性,是 1 型单纯疱疹病毒(HSV-1)的有效抑制剂。 | |||
T6062 |
Brefeldin A
BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin |
ATPase; Mitophagy; Antibiotic; Autophagy; HSV; CRISPR/Cas9 | Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology |
Brefeldin A (Cyanein) 属于大环内酯类抗生素,是一种 ATPase 抑制剂 (IC50=0.2 μM)。Brefeldin A 可以诱导肿瘤细胞分化和凋亡,也具有抑制自噬的活性。 | |||
T0895 |
Oxytetracycline
土霉素,Terramycin |
ribosome; Endogenous Metabolite; Antibacterial; Antibiotic; HSV | Metabolism; Microbiology/Virology |
Oxytetracycline (Terramycin) 是一种四环素类抗生素。它强力抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂,可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合,具有抗 HSV-1的活性。 | |||
T3375 |
Verbascoside
毛蕊花苷,麦角甾苷,Kusaginin,Acteoside,TJC160 |
Apoptosis; PARP; Antibacterial; PKC; p53; HSV | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Microbiology/Virology |
Verbascoside (Kusaginin) 是从Lantana camara 中得到的糖苷类物质,是具有ATP 竞争性的PKC 抑制剂,IC50值为 25 µM,它还有抗炎,抗肿瘤,抗神经性疼痛等作用。 | |||
T0884 |
1-Docosanol
Behenic alcohol,Behenyl alcohol,n-Docosanol,二十二醇,Docosanol |
Antifection; HSV | Microbiology/Virology |
1-Docosanol (Behenic alcohol) 是一种具有抗病毒活性的饱和 22 碳脂肪醇,局部用于治疗复发性单纯性唇疱疹发作并缓解相关疼痛并可能有助于更快地治愈疮。 | |||
T1131 |
Ivermectin
MK-933,伊维菌素 |
Mitophagy; GluCls; P2X Receptor; SARS-CoV; HIV Protease; Antibiotic; Parasite; Autophagy; HSV | Autophagy; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
Ivermectin (MK-933) 是谷氨酸门控氯离子通道激活剂,具有抗寄生虫活性。它特异性抑制Impα/β1 介导的核导入,还抑制牛疱疹病毒 1 复制并抑制BoHV-1DNA 聚合酶的核输入。它具有很强的抗病毒活性。它也是P2X4和 α7nAChRs 的正异构效应物。 | |||
T6624 |
Oxytetracycline Dihydrate
土霉素二水合物,地霉素,Terramycin Dihydrate |
Others; Endogenous Metabolite; Antibacterial; Antibiotic; HSV | Metabolism; Microbiology/Virology; Others |
Oxytetracycline Dihydrate (Terramycin Dihydrate) 是一种四环素类抗生素,可抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂,可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合,还具有抗 HSV-1的活性。 | |||
T5S0018 |
Betulonic acid
路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid |
Parasite; HSV | Microbiology/Virology |
Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物,具有抗肿瘤,抗炎,抗寄生虫和抗病毒的活性。 | |||
T3S1068 |
Oxyresveratrol
trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene |
Tyrosinase; Autophagy; HSV | Autophagy; Microbiology/Virology; Proteases/Proteasome |
Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂,对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1,HSV-2和水痘带状疱疹病毒,具有神经保护作用。它是天然抗氧化剂和自由基清除剂。 | |||
T2927 |
Trigonelline chloride
Gynesine Hydrochloride,盐酸葫芦巴碱,Coffearine Hydrochloride,Nicotinic acid N-methylbetaine Hydrochloride,Trigonelline hydrochloride |
Others; Antibacterial; Antifungal; HSV | Microbiology/Virology; Others |
Trigonelline chloride (Coffearine Hydrochloride) 是一种大量存在于咖啡中的生物碱,具有潜在抗糖尿病活性。它还具有抗HSV-1,抗菌和抗真菌活性。 | |||
T1272 |
Cytarabine
阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine |
Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; HSV | Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Cytarabine (Ara-C) 是一种核苷类似物,一种 DNA 合成抑制剂 (IC50=16 nM)。Cytarabine 可以抑制 DNA 聚合酶,诱导细胞周期阻滞、细胞自噬和凋亡。Cytarabine 具有抗肿瘤活性。 | |||
T3813 |
20(R)-Ginsenoside Rh2
20(R)-人参皂苷 RH2,(20R)Ginsenoside Rh2,Ginsenoside Rh2,20(R)-人参皂苷Rh2 |
Apoptosis; MMP; HSV | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) 是人参皂苷 Rh2 的次要立体异构体,具有基质金属蛋白酶抑制作用。它有抗癌、抗炎和抗氧化活性。 | |||
T0853L |
Adenosine 5'-monophosphate monohydrate
5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid |
AMPK; Adenosine Receptor; HSV | Chromatin/Epigenetic; GPCR/G Protein; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling |
Adenosine 5'-monophosphate monohydrate (5'-AMP) 是一种核苷酸,用作 RNA 中的单体。它是一个腺苷 A1受体激动剂,对HSV-1和HSV-2具有显著的抗病毒活性。 | |||
T1506 |
Vidarabine
Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A |
Nucleoside Antimetabolite/Analog; Tyrosine Kinases; DNA/RNA Synthesis; Antibiotic; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Tyrosine Kinase/Adaptors |
Vidarabine (Adenine Arabinoside) 是从链霉菌分离的核苷类抗生素,能抗单纯性疱疹和水痘-带状疱疹病毒。它对 HSV-1 和 HSV-2 的 IC50值分别为 9.3 μg/ml 和 11.3 μg/ml。 | |||
T21430 |
Oxytetracycline Hydrochloride
Biosolvomycin,盐酸土霉素,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin |
Antiviral; Endogenous Metabolite; Antibacterial; HSV | Immunology/Inflammation; Metabolism; Microbiology/Virology |
Oxytetracycline Hydrochloride (Dalimycin) 是由 Streptomyces rimosus 生产的,一种具有抗菌活性的四环素衍生物。它干扰氨酰-tRNA 与 mRNA-核糖体复合物的结合,从而阻止肽延伸并抑制蛋白质合成。 | |||
T5429 |
Theaflavin 3,3'-digallate
茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG |
Virus Protease; Antioxidant; HIV Protease; HSV | Microbiology/Virology; oxidation-reduction; Proteases/Proteasome |
Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂,IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制,可抑制 gp41 和 NS2B-3 蛋白酶的活性,并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚,有抗肿瘤作用。 | |||
T2S1865 |
Octyl gallate
Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯 |
Antioxidant; Influenza Virus; Reactive Oxygen Species; Antibacterial; Antifungal; HSV | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction |
Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用,有选择性和敏感性的荧光特性,广泛用作食品添加剂。它对 HSV-1,水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。 | |||
T2822 |
Ginsenoside Rb1
Gypenoside Ⅲ,人参皂苷Rb1,人参皂苷 Rb1,Gypenoside III |
ATPase; Mitophagy; IRAK; NF-κB; Autophagy; HSV | Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; NF-κB |
Ginsenoside Rb1 (Gypenoside Ⅲ) 是中药人参的成分,可能具有抑制或阻止肿瘤生长的特性。 | |||
T6742 |
2-Deoxy-D-glucose
2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,D-2-脱氧葡萄糖,NSC 15193,2-DG,2-脱氧-D-葡萄糖 |
Apoptosis; Hexokinase; HSV | Apoptosis; Metabolism; Microbiology/Virology |
2-Deoxy-D-glucose (2-DG) 是葡萄糖的类似物,是一种糖酵解抑制剂。2-Deoxy-D-glucose 具有抗病毒活性,还具有抑制细胞增殖、诱导细胞凋亡的活性。 | |||
T4S0554 |
Theaflavine-3,3'-digallate
TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素 |
Others | Others |
Theaflavine-3,3'-digallate (theaflavin digallate) 和乳酸一起可以减少单纯疱疹病毒的传播。 | |||
T8071 |
L-Lysine hydrochloride
赖氨酸盐酸盐,Lysine hydrochloride,L-赖氨酸盐酸盐 |
Virus Protease | Microbiology/Virology |
L-Lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
T14304 |
Aphidicolin
|
Others | Others |
Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA | |||
T4S0999 |
(2S)-Isoxanthohumol
Isoxanthohumol,(2S)-异黄腐酚,异黄腐醇 |
Virus Protease; HSV | Microbiology/Virology |
(2S)-Isoxanthohumol 是一种由啤酒花原异戊烯基二氢黄酮 Isoxanthohumol 的微生物转化代谢物。 | |||
T2A2498 |
L-Lysine
Aminutrin,Lysine Acid,lysine,L-赖氨酸,赖氨酸 |
Virus Protease; Endogenous Metabolite; Antifection | Metabolism; Microbiology/Virology |
L-Lysine (Aminutrin) 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
TN2063 |
Physalin B
NSC-287088 |
Apoptosis; NF-κB; Akt; PI3K; Nrf2; NOD | Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling |
Physalin B 是茄科植物的主要活性化合物之一,具有广泛的生物活性,可用于治疗炎症湿疹和疱疹等疾病。Physalin B 通过激活 PI3K/Akt 通路抑制 NF-κB 和 NLRP3,从而改善脂多糖诱导的急性肺损伤造成的炎症反应。Physalin B 通过激活 Nrf2 通路抑制 PDGF-BB 诱导的 VSMC 增殖、迁移和表型转化。Physalin B 通过抑制 LAP2α-HDAC1 介导的胶质瘤相关癌基因 1 的去乙酰化和肝星状细胞活化来发挥抗肿瘤活性。 | |||
TN1671 |
Ganoderone A
|
Integrase; HSV | Microbiology/Virology |
Ganoderone A exhibits potent inhibitory activity against herpes simplex virus. | |||
T17270 |
Yatein
|
Others | Others |
Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity. | |||
TN4455 |
Lucialdehyde B
|
Integrase; HSV | Microbiology/Virology |
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines. | |||
T3930 |
Taraxerol acetate
醋酸蒲公英霜,Taraxeryl acetate |
Phosphatase; HSV | Metabolism; Microbiology/Virology |
Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activity, could be attributed due to PTP | |||
TN1843 |
Kushenol K
|
PDE; HSV | Metabolism; Microbiology/Virology |
Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K shows weak antiviral activity against Herpes simplex virus types I and II. | |||
TN4587 |
Mulberrofuran C
|
HSV | Microbiology/Virology |
Mulberrofuran C shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 0.41 ± 0.48 uM ; it also shows protective effects on glutamate-induced cell death with the EC50 value of 16.50 ± 7.82 uM. Mulberrofuran C has antiviral effects against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2). | |||
T79987 |
Cangorinine E-1
|
HSV | Microbiology/Virology |
Cangorinine E-1 (compound 11) 为一种倍半萜类的二氢沉香呋喃衍生物,对 II 型单纯疱疹病毒(HSV)展现出轻度抑制效果。 | |||
TN3559 |
Cabraleahydroxylactone
|
HSV | Microbiology/Virology |
Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows antiviral activity against herpes simplex virus type-1 with an IC50 value of 3.20 ug/mL, in comparison with the standard acyclovir (IC50=1.90ug/mL). | |||
TN3925 |
Eichlerianic acid
|
HSV | Microbiology/Virology |
Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I and II in vitro. Eichlerianic acid shows weak cytotoxicity (IC50 6.87 to >40 μM) against human cancer cell (HL-60, SMMC-7721, A-549, MCF-7 and SW480). | |||
TN7265 |
16-epi Latrunculin B
|
Others | Others |
16-epiLatrunculin B, a stereoisomer of the actin polymerization inhibitor latrunculin B, was initially isolated from the Red Sea sponge N. magnifica. At concentrations of 5-10 µg/ml, it disrupts microfilament activity in actin disruption assays and exhibits cytotoxic effects on mouse KA31T and NIH3T3 tumor cells, with GI50 values of 1 and 4 µg/ml, respectively. Furthermore, it shows antiviral activity against herpes simplex type 1 virus, with an ED50 of 1 µg/ml. | |||
TN5014 |
Shoreic acid
|
Antifection; HSV | Microbiology/Virology |
Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albicans and T. mentagrophytes with AI | |||
T35779 |
Oosporein
|
Others | Others |
Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ... | |||
T83693 |
Magainin 2 TFA
MG2 |
Others | Others |
Magainin 2是一种从非洲爪蟾(X. laevis)皮肤中分离出的阳离子肽,具有宿主防御和抗菌活性。该化合物对细菌E. coli、K. pneumoniae、S. epidermidis、S. aureus及真菌C. albicans表现出活性(MICs分别为5、10、10、50和80 µg/ml)。Magainin 2(20 µM)能降低猕猴桃花粉的萌发率和平均管长。在被单纯疱疹病毒1型(HSV-1)或2型(HSV-2)感染的Vero细胞中,它可减少病毒复制(EC50s分别为22.16和19.8 µM),同时不影响细胞活性,其50%细胞毒性浓度值(CC50)大于100 µM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01464 |
USP7 Protein, Human, Recombinant (aa 208-560)
TEF1,HAUSP,ubiquitin specific peptidase 7 (herpes v... |
Human | Baculovirus Insect Cells |
USP7 Protein, Human, Recombinant (aa 208-560) is expressed in Baculovirus insect cells. The predicted molecular weight is 41 kDa and the accession number is Q93009-1. | |||
TMPY-01465 |
USP7 Protein, Human, Recombinant (His & GST)
HAUSP,ubiquitin specific peptidase 7 (herpes virus-... |
Human | Baculovirus Insect Cells |
USP7 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 156 kDa and the accession number is Q93009-1. | |||
TMPY-01463 |
USP7 Protein, Human, Recombinant (aa 208-560, His & GST)
ubiquitin specific peptidase 7 (herpes virus-associ... |
Human | Baculovirus Insect Cells |
USP7 Protein, Human, Recombinant (aa 208-560, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.8 kDa and the accession number is Q93009-1. | |||
TMPJ-00323 |
Nectin-2 Protein, Mouse, Recombinant (hFc)
Herpes Virus Entry Mediator B,PVRL2,Poliovirus Rece... |
Mouse | HEK293 Cells |
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju... | |||
TMPJ-00620 |
HVEM Protein, Rhesus macaque, Recombinant (His)
TNFRSF14,HVEA,Tumor Necrosis Factor Receptor Superfamily Mem... |
Rhesus | HEK293 Cells |
HVEM Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-40 KDa and the accession number is F7GSW4. | |||
TMPJ-01416 |
HVEM Protein, Rhesus macaque, Recombinant (hFc)
CD270,TNFRSF14,TR2,Herpesvirus Entry Mediator A,Tum... |
Rhesus | HEK293 Cells |
HVEM Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A0A2K5W0R1. | |||
TMPY-00144 |
Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein (His)
BLLF1,gp22 |
EBV | Baculovirus Insect Cells |
Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.7 kDa and the accession number is A0A0B6VN60. | |||
TMPH-01441 |
Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein G (His)
Envelope glycoprotein G,gG-1,gG |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein G (His) is expressed in in vitro E. coli expression system. | |||
TMPH-01445 |
Human herpesvirus 1 (HHV-1) (strain F) Tegument protein VP16 (His & SUMO)
Alpha-TIF,Vmw65,ICP25,Alpha trans-inducing protein,Tegument ... |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain F) Tegument protein VP16 (His & SUMO) is expressed in E. coli. | |||
TMPH-01447 |
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His)
gC,Envelope glycoprotein C |
HHV-2 | E. coli |
Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Plays also a role in host immune evasion by inhibiting the host complement cascade activation. Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 50.5 kDa and the accession number is Q89730. | |||
TMPH-01458 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Protein U22 (His)
Protein U22,U22 |
HHV-6B | E. coli |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Protein U22 (His) is expressed in in vitro E. coli expression system. | |||
TMPH-01455 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Triplex capsid protein 1 (His)
Triplex capsid protein 1,TRX1 |
HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Triplex capsid protein 1 (His) is expressed in E. coli. | |||
TMPH-01459 |
Human herpesvirus 7 (HHV-7) (strain JI) Probable ganciclovir kinase (His & Myc)
Probable ganciclovir kinase,U69 |
HHV-7 | E. coli |
Human herpesvirus 7 (HHV-7) (strain JI) Probable ganciclovir kinase (His & Myc) is expressed in E. coli. | |||
TMPH-01449 |
Human herpesvirus 2 (HHV-2) (strain HG52) Tegument protein VP22 (His)
Tegument protein VP22 |
HHV-2 | E. coli |
Human herpesvirus 2 (HHV-2) (strain HG52) Tegument protein VP22 (His) is expressed in E. coli. | |||
TMPH-01443 |
Human herpesvirus 1 (HHV-1) (strain KOS) Glycoprotein C (His & KSI)
Envelope glycoprotein C,gC |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain KOS) Glycoprotein C (His & KSI) is expressed in E. coli. | |||
TMPH-01452 |
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc)
U96/U97/U98/U99/U100,Glycoprotein 105 |
HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc) is expressed in E. coli. | |||
TMPH-01457 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)
mRNA export factor ICP27 homolog |
HHV-6B | E. coli |
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs. Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P52539. | |||
TMPH-01451 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Envelope glycoprotein B (His & Myc)
gB,Envelope glycoprotein B |
HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Envelope glycoprotein B (His & Myc) is expressed in E. coli. | |||
TMPH-01446 |
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein B (His & SUMO)
gB,Envelope glycoprotein B |
HHV-2 | E. coli |
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein B (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.4 kDa and the accession number is P08666. | |||
TMPH-01456 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc)
Glycoprotein 105,HCLF1 protein,Glycoprotein Q-80k,Glycoprote... |
HHV-6B | E. coli |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc) is expressed in E. coli. | |||
TMPH-01453 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Glycoprotein U22 (His)
U22,Glycoprotein U22 |
HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Glycoprotein U22 (His) is expressed in in vitro E. coli expression system. | |||
TMPH-01442 |
Human herpesvirus 1 (HHV-1) (strain KOS) glycoprotein L/gL Protein (His & Myc & SUMO)
gL,Envelope glycoprotein L |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain KOS) glycoprotein L/gL Protein (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-03610 |
Suid herpesvirus 1 (SuHV-1) Glycoprotein B/gB Protein (His)
Envelope glycoprotein B,gB |
SuHV-1 | E. coli |
Suid herpesvirus 1 (SuHV-1) Glycoprotein B/gB Protein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 11.8 kDa and the accession number is P08355. | |||
TMPH-01444 |
Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His)
US12 protein,Infected cell protein 47,ICP47 protein,US12,Vmw... |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His) is expressed in E. coli. | |||
TMPH-01448 |
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein E (His)
gE,Envelope glycoprotein E,gE-2 |
HHV-2 | E. coli |
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein E (His) is expressed in in vitro E. coli expression system. | |||
TMPH-01454 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Probable ganciclovir kinase (His)
U69,Probable ganciclovir kinase |
HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Probable ganciclovir kinase (His) is expressed in E. coli. | |||
TMPH-01450 |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His)
Phosphoprotein P41,U27,DNA polymerase processivity factor,Po... |
HHV-6A | P. pastoris (Yeast) |
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His) is expressed in Yeast. | |||
TMPH-01440 |
Human herpesvirus 1 (HHV-1) (strain KOS) Envelope glycoprotein D (His & Myc)
gD,Envelope glycoprotein D |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain KOS) Envelope glycoprotein D (His & Myc) is expressed in E. coli. | |||
TMPH-01439 |
Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein C (His & Myc)
gC,Envelope glycoprotein C |
HHV-1 | E. coli |
Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein C (His & Myc) is expressed in E. coli. | |||
TMPY-06802 |
HSV 2 (strain 333) Glycoprotein D/gD Protein (His)
|
HSV2 | HEK293 Cells |
Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for significant neurological morbidity, perhaps more than any other virus. Herpes simplex virus type 2–associated neurological disease may result from primary infection or reactivation of latent HSV-2. Common severe infections include encephalitis, meningitis, neonatal herpes, and, in immun... | |||
TMPY-06900 |
HSV 2 (strain HG52) Glycoprotein E/gE Protein (His)
|
HSV2 | Baculovirus Insect Cells |
Herpes simplex virus type 2 (HSV-2) is the predominant cause of genital ulcer disease in human. Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to immune evasion by HSV. | |||
TMPJ-00129 |
BTLA Protein, Human, Recombinant (His)
B- and T-Lymphocyte-Associated Protein,CD272,BTLA,B- and T-L... |
Human | HEK293 Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0013 |
Acyclovir-d4
|
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Acyclovir-d4 是 Acyclovir 的氘代化合物。Acyclovir 的 CAS 号为 59277-89-3。Acyclovir是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM),HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。 | |||
TMIJ-0521 |
L-Lysine-4,4,5,5-d4 Hydrochloride
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L-Lysine-4,4,5,5-d4 Hydrochloride 是 L-Lysine Hydrochloride 的氘代化合物。L-Lysine Hydrochloride 的 CAS 号为 657-27-2。L-lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
TMIJ-0380 |
L-Lysine-13C6-15N2 Hydrochloride
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L-Lysine-13C6-15N2 Hydrochloride 是 L-Lysine Hydrochloride 的 13C 和 15 N 的标记化合物。L-Lysine Hydrochloride 的 CAS 号为 657-27-2。L-lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 |