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Targets Recommended: Sodium Channel

11

抑制剂 & 化合物

6

天然产物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2131 Articaine hydrochloride

Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045

Sodium Channel Membrane transporter/Ion channel
Articaine hydrochloride (Hoe-045) 一种牙科局部麻醉剂。
T2568L Felypressin acetate

2-(L-Phenylalanine)-8-L-lysinevasopressin,醋酸苯赖加压素,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2

Vasopressin Receptor GPCR/G Protein
Felypressin acetate (PLV-2) 是加压素 1 的激动剂,作用于所有精氨酸加压素受体 1AS。 Felypressin acetate 可用于牙科手术。
T2568 Felypressin

Octapressin,Felypressin Acetate,PLV-2,H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,苯赖加压素

Vasopressin Receptor GPCR/G Protein
Felypressin (Octapressin) 是一种加压素 1 激动剂,也是血管收缩剂,可用于牙科手术中。
T0305 Erythrosine B

Erythrosine I,Erythrosin extra bluish,Erythrosin B,赤藓红B

Others Others
Erythrosine B (Erythrosine I) 是一种已被用于开发动物模型的新型光敏剂,在食品和纺织工业的人造染料中具有广泛的应用。
T0578 Erythrosin B

Iodeosin,Tetraiodofluorescein,藻红B

Others Others
Erythrosin B (Iodeosin) 是一种四碘荧光素,在某些食物(樱桃、鱼)中用作红色色素,用作某些细胞类型的染色剂,以及用作牙菌斑的披露物。其分子结构与甲状腺素相似。
T0900 Cetylpyridinium chloride monohydrate

Hexadecylpyridinium chloride monohydrate,十六烷基氯化吡啶

Antibacterial; Antibiotic Microbiology/Virology
Cetylpyridinium chloride monohydrate (Hexadecylpyridinium chloride monohydrate) 是阳离子季铵, 是一种能杀死细菌和其他微生物的防腐剂, 用于某些类型的漱口水, 牙膏, 咽喉和鼻腔喷雾剂中, 可有效预防牙斑和减少牙龈炎。
T68705 Salifluor

Others Others
Salifluor is a broad spectrum antimicrobial agent that has been investigated for its abilities to inhibit dental plaque formation.
T33787 Olaflur

SKF 38095,GA 297,SK&F 38095

Others Others
Olaflur is a compound that prevents dental caries.
T68494 Octenidine saccharin

Others Others
Octenidine saccharin is a Dental Plaque Inhibitor
T75324 Azidocillin

Others Others
Azidocillin 是一种半合成青霉素,是一种具有口服活性的 β-内酰胺类抗生素 (antibiotic)。Azidocillin 具有叠氮化功能,并在细菌内 (bacteria) 保持靶向活性。Azidocillin 可用于研究牙科手术引起的骨炎,或中耳炎、肠球菌败血症和其他细菌感染性疾病。
T38048 Globotetraosylceramides (porcine RBC)

Others Others
Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides ...

化合物

Articaine hydrochloride
Cat.No: T2131
Synonym: Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045
Target: Sodium Channel
Felypressin acetate
Cat.No: T2568L
Synonym: 2-(L-Phenylalanine)-8-L-lysinevasopressin,醋酸苯赖加压素,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2
Target: Vasopressin Receptor
Felypressin
Cat.No: T2568
Synonym: Octapressin,Felypressin Acetate,PLV-2,H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,苯赖加压素
Target: Vasopressin Receptor
Erythrosine B
Cat.No: T0305
Synonym: Erythrosine I,Erythrosin extra bluish,Erythrosin B,赤藓红B
Target: Others
Erythrosin B
Cat.No: T0578
Synonym: Iodeosin,Tetraiodofluorescein,藻红B
Target: Others
Cetylpyridinium chloride monohydrate
Cat.No: T0900
Synonym: Hexadecylpyridinium chloride monohydrate,十六烷基氯化吡啶
Target: Antibacterial, Antibiotic
Salifluor
Cat.No: T68705
Synonym:
Target: Others
Olaflur
Cat.No: T33787
Synonym: SKF 38095,GA 297,SK&F 38095
Target: Others
Octenidine saccharin
Cat.No: T68494
Synonym:
Target: Others
Azidocillin
Cat.No: T75324
Synonym:
Target: Others
Globotetraosylceramides (porcine RBC)
Cat.No: T38048
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3400 Bakuchiol

p38 MAPK; DNA/RNA Synthesis; Autophagy Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK
Bakuchiol 是一种从补骨脂种子中提取的植物雌激素,具有抗肿瘤和抗蠕虫特性,以及细胞毒活性和抗菌活性。
T2S0490 Eugenol acetate

Acetyleugenol,乙酰丁香酚,Aceteugenol,乙酸丁香酚酯,Eugenyl acetate,1,3,4-Eugenol acetate

Others; Antibacterial; Antifungal Microbiology/Virology; Others
Eugenol acetate (Aceteugenol) 是来自丁香植物 Syzygiumaromaticum 的一种化学成分,具有抗菌、抗毒和抗氧化活性。
T38706 Erlose

Others Others
Erlose, a trisaccharide present in soybean aphid honeydew and composed of sucrose, acts as a sweetener substitute to inhibit dental caries formation by oral microorganisms, primarily Streptococcus mutans. Erlose can serve as a reference compound in high-performance liquid chromatography (HPLC) methods employed for the analysis of sugar content in various food samples.
TN1938 Mogroside VI

罗汉果甜苷 VI,罗汉果甜苷VI

Antifection Microbiology/Virology
Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial properties, no-calorie levels related to obesity, and a low glycemic index to help manage blood suga
TN4437 Licorisoflavan A

MMP; IL Receptor; NF-κB; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; NF-κB; Proteases/Proteasome
Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis.L
T79993 Oleanolic aldehyde

Others Others
Oleanolic aldehyde 是一种具有抗菌性质的化合物,能够抑制口腔内细菌生长。该化合物对变形链球菌和牙龈卟啉单胞菌——与龋齿和牙周病有关的细菌——显示出显著的抑制效果,其最低抑菌浓度(MICs)分别为488 μg/mL和250 μg/mL。

天然产物

Bakuchiol
Cat.No: T3400
Synonym:
Target: p38 MAPK, DNA/RNA Synthesis, Autophagy
Eugenol acetate
Cat.No: T2S0490
Synonym: Acetyleugenol,乙酰丁香酚,Aceteugenol,乙酸丁香酚酯,Eugenyl acetate,1,3,4-Eugenol acetate
Target: Others, Antibacterial, Antifungal
Erlose
Cat.No: T38706
Synonym:
Target: Others
Mogroside VI
Cat.No: TN1938
Synonym: 罗汉果甜苷 VI,罗汉果甜苷VI
Target: Antifection
Licorisoflavan A
Cat.No: TN4437
Synonym:
Target: MMP, IL Receptor, NF-κB, DNA/RNA Synthesis
Oleanolic aldehyde
Cat.No: T79993
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-01061 FGF-10 Protein, Human, Recombinant

fibroblast growth factor 10,KGF2

Human E. coli
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla...
TMPH-03600 Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)

gtfC,Glucosyltransferase-SI,Dextransucrase,Sucrose 6-glucosy...

Streptococcus mutans E. coli
Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris. Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is P13470.
TMPY-04303 FAM20C Protein, Human, Recombinant (His)

GEF-CK,DMP4,RNS,DMP-4,family with sequence similarity 20, me...

Human Baculovirus Insect Cells
The Family with sequence similarity 20 member C (FAM20C) catalyzes the phosphorylation of secreted proteins, and participates in a variety of biological processes, including cell proliferation, migration, mineralization, and phosphate homeostasis. FAM20C is an evolutionarily reserved molecule highly expressed in mineralized tissues. Mutations in the Family with sequence similarity (FAM) 20 gene family are associated with mineralized tissue phenotypes in humans. Among these genes, FAM20A mutation...
TMPY-01900 Kallikrein 4/KLK4 Protein, Human, Recombinant (His)

PSTS,kallikrein,kallikrein-related peptidase 4,EMSP,EMSP1,AR...

Human HEK293 Cells
Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transi...
TMPY-03291 SMAD2 Protein, Mouse, Recombinant (His & GST)

mMad2,Smad-2,7120426M23Rik,Madr2,Madh2,SMAD family member 2

Mouse Baculovirus Insect Cells
SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD2 mediates the signal of the TGF-beta, and therefore regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein...
TMPY-03728 CCL28 Protein, Human, Recombinant (His)

MEC,SCYA28,chemokine (C-C motif) ligand 28,CCK1

Human E. coli
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues an...

重组蛋白

FGF-10 Protein, Human, Recombinant
Cat.No: TMPY-01061
Species: Human
Expression System: E. coli
Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)
Cat.No: TMPH-03600
Species: Streptococcus mutans
Expression System: E. coli
FAM20C Protein, Human, Recombinant (His)
Cat.No: TMPY-04303
Species: Human
Expression System: Baculovirus Insect Cells
Kallikrein 4/KLK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01900
Species: Human
Expression System: HEK293 Cells
SMAD2 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-03291
Species: Mouse
Expression System: Baculovirus Insect Cells
CCL28 Protein, Human, Recombinant (His)
Cat.No: TMPY-03728
Species: Human
Expression System: E. coli
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