320
152
69
3
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T80707 |
α-Hemolysin (Staphylococcus aureus)
|
||
α-Hemolysin (Staphylococcus aureus) 是一种由金黄色葡萄球菌分泌的毒力因子,具有破坏宿主细胞质膜的多肽特性。α-Hemolysin 绑定细胞表面后,通过其单体组装成同型七聚体预孔结构,并转变为成熟的跨膜孔,形成水通道。这一过程促使 K+ 和 Ca2+ 离子通过膜,触发靶细胞的坏死性死亡。 | |||
T5038 |
Cephapirin Sodium
|
Antibacterial; Antibiotic | Microbiology/Virology |
Cephapirin sodium 是一种半合成头孢菌素类抗生素,对革兰氏阳性菌和革兰氏阴性菌有杀菌作用。 | |||
T1224 |
Cefuroxime sodium
Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素,增加了对 β-内酰胺酶的稳定性。 | |||
T8507 |
MAC-545496
|
Antibacterial | Microbiology/Virology |
MAC-545496 是一种抗毒剂,可逆转耐甲氧西林的菌株中的 β-内酰胺耐药性。它是糖肽抗性相关蛋白 R 的纳摩尔抑制剂,对全长 GraR 蛋白具有很强的结合亲和力。 | |||
T22269 |
Benzyldodecyldimethylammonium Chloride Dihydrate
|
Antibacterial | Microbiology/Virology |
Benzyldodecyldimethylammonium chloride dihydrate 可以用作杀虫试剂,可以靶向耐药性细菌,如耐甲氧西林金黄色葡萄球菌、耐多药铜绿假单胞菌等,且具有浓度依赖性。 | |||
T19717 |
Cyclo-L-Trp-L-Trp
|
Antifungal | Microbiology/Virology |
Cyclo-L-Trp-L-Trp 是一种广谱抗真菌剂。它还诱导组蛋白的高度乙酰化。 | |||
T1440 |
Ethacridine lactate monohydrate
乳酸依沙吖啶一水物,利凡诺 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ethacridine lactate monohydrate 是一种聚 (ADP-核糖) 糖基水解酶 (PARG) 抑制剂,有抗金黄色葡萄球菌和其他革兰氏阳性球菌的活性。它也是抗菌剂和流产剂。 | |||
T19794 |
Temafloxacin
替马沙星,Omniflox |
Antibiotic | Microbiology/Virology |
Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂,对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。 | |||
T1031 |
Cloxacillin sodium monohydrate
Cloxacillin Sodium,Bactopen,氯唑西林钠一水合物 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cloxacillin sodium monohydrate (Cloxacillin Sodium) 有抗菌作用,对Staphylococcus aureus25923 的最小抑菌浓度为256 mg/L。 | |||
T5967 |
Ethacridine lactate
乳酸依沙吖啶,Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE |
Others; Antibacterial | Microbiology/Virology; Others |
Ethacridine lactate (Acrinol) 是一种聚 (ADP-核糖) 糖水解酶 (PARG) 抑制剂,也是一种抗菌剂和流产剂。它有抗金黄色葡萄球菌和其他革兰氏阳性球菌的活性。 | |||
T1283 |
Clinafloxacin
克林沙星,PD 127391,CI-960,AM-1091 |
Antibacterial; Antibiotic | Microbiology/Virology |
Clinafloxacin (CI-960) 是一种高效广谱氟喹诺酮类抗生素,抑制革兰氏阳性、革兰氏阴性和厌氧病原体。它对金黄色葡萄球菌的 DNA 促旋酶和拓扑异构酶 IV 有抑制作用,IC50值分别为 0.92 µg/ml 和 1.62 µg/ml。 | |||
T1389 |
Dyclonine hydrochloride
盐酸达克罗宁,Dyclocaine hydrochloride,Dyclonine HCl |
Sodium Channel; Antibacterial; Antifungal | Membrane transporter/Ion channel; Microbiology/Virology |
Dyclonine hydrochloride (Dyclonine HCl) 是润喉片的有效成分,具有显著的杀菌和杀真菌作用。 | |||
T7804 |
Garenoxacin mesylate hydrate
Garenoxacin mesylate [USAN],加雷沙星甲磺酸盐,BMS284756 (Mesylate hydrate) |
Antibacterial | Microbiology/Virology |
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) 是一种新型口服 des-fluoro(6) 喹诺酮,具有强抗菌活性,抗呼吸道病原体。 | |||
T0964 |
Floxuridine
氟尿苷,5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 |
Apoptosis; Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis; Antibacterial; HSV | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Floxuridine (FUDR) 是一种嘧啶类似物,也是一种抗肿瘤代谢物。它抑制胸苷酸合成酶,导致 DNA 合成中断和细胞毒性。它是一种可诱导细胞凋亡的金黄色葡萄球菌感染抑制剂 ,具有抗HSV 和CMV 病毒的作用。 | |||
T1293 |
Gatifloxacin
BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155,加替沙星 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Gatifloxacin (CG5501) 是一种具有广谱抗菌活性的氟喹诺酮类抗生素。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg/ml) 和细菌 II 型拓扑异构酶(IC50=13.8 μg/ml)。在动物模型中,它有抗细菌性结膜炎作用。 | |||
T7179 |
Garenoxacin
BMS284756,加雷沙星 |
Antibacterial | Microbiology/Virology |
Garenoxacin (BMS284756) 是一种新型的口服 des-fluoro(6) 喹诺酮,有抗菌活性,可抑制呼吸道病原体。 | |||
T9508 |
MONOCAPRYLIN
Sefsol 318,Glyceryl monocaprylate,辛酸甘油酯 |
Antibacterial | Microbiology/Virology |
Monocaprylin (Sefsol 318) 是一种辛酸甘油单辛酸酯,有出色的抗菌活性,可抑制多种食源性致病和腐败微生物,有用于替代食品防腐剂的研究潜力。 | |||
T64316 |
VP-4604
1-((4-Nitrophenyl)sulfonyl)piperidine |
Others | Others |
VP-4604是一种有效的抗耐甲氧西林金黄色葡萄球菌(MRSA)化合物。VP-4604对金黄色葡萄球菌展现出显著的抑制微生物生长的作用,MIC 为4-8μg/mL。VP-4604抑制耐甲氧西林金黄色葡萄球菌的生长,其生长抑制率达到95%以上。 | |||
T21358 |
Dalbavancin
BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl,达巴万星 |
Antibacterial; Antibiotic | Microbiology/Virology |
Dalbavancin (BI-397) HCl 是一种半合成的脂糖肽抗生素,对革兰氏阳性细菌有杀菌活性。Dalbavancin 抑制金黄色葡萄球菌和炭疽芽孢杆菌的 MIC90分别为 0.06 μg/mL 和 0.25 μg/mL。 | |||
T12126 |
MUT056399
Fab-001 |
Antibacterial | Microbiology/Virology |
MUT056399 (Fab-001) 是一种金黄色葡萄球菌和大肠杆菌的 FabI 酶的高效抑制剂,IC50值分别为 12 nM 和 58 nM。 | |||
TQ0063 |
Zoliflodacin
ETX0914,AZD0914 |
DNA gyrase; DNA/RNA Synthesis; Topoisomerase; Antibacterial | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Zoliflodacin (ETX0914) 是一种新型螺旋嘧啶三酮,对革兰氏阳性和阴性生物有抗菌活性,对金黄色葡萄球菌的b>MIC90值为0.25 μg/mL。他也是细菌DNA 促旋酶/拓扑异构酶的抑制剂。 | |||
T2331 |
Solithromycin
索利霉素,OP-1068,CEM-101 |
Antibacterial; Antibiotic | Microbiology/Virology |
Solithromycin (OP-1068) 是口服可生物利用的抗菌剂,抑制肺炎链球菌、葡萄球菌、金黄色葡萄球菌和流感嗜血杆菌的细胞活力、蛋白质合成和生长速率, IC50 值分别为 7.5 ng/mL、40 ng/mL 和 125 ng/mL。它可与核糖体的大 50S 亚基结合抑制蛋白质生物合成。 | |||
T60093 |
CHEMBL1380345
N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide) |
Antibacterial | Microbiology/Virology |
CHEMBL1380345 对金黄色葡萄球菌、蜡状芽孢杆菌和大肠杆菌具有抗菌活性,pMIC 值分别为 3.64、3.56 和 3.70。 | |||
T33470 |
Monoctanoin
辛酸2,3-二羟基酯,Glyceryl 1-caprylate,Moctanin |
Antibacterial | Microbiology/Virology |
Monoctanoin (Glyceryl 1-caprylate) 对金黄色葡萄球菌和大肠杆菌具有抗菌活性。 | |||
T17254 |
Amifloxacin
Win49375,氨氟沙星 |
Antibacterial | Microbiology/Virology |
Amifloxacin (Win49375) 是有效的喹诺酮类抗菌剂。 | |||
T71699 |
Lanopepden mesylate
GSK 1322322 mesylate,GSK-1322322J mesylate |
Antibacterial | Microbiology/Virology |
Lanopepden mesylate 是一种肽去甲酰酶抑制剂,可抑制金黄色葡萄球菌。 | |||
T20936 |
Lauramine oxide
LDAO,Dimethylaurylamine oxide,十二烷基二甲基氧化胺,Refan,Lauryldimethylamine oxide |
Antibacterial | Microbiology/Virology |
Lauramine oxide (Refan) 对大肠杆菌和金黄色葡萄球菌等常见细菌有效,但它是非变性的,可用于溶解蛋白质。 | |||
TQ0077 |
Ceftobiprole
Ro 63-9141,BAL 9141,头孢吡普 |
Antibacterial | Microbiology/Virology |
Ceftobiprole (Ro 63-9141) 是一种广谱头孢菌素,对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。 | |||
T61159 |
Antibacterial agent 26
|
Antibacterial | Microbiology/Virology |
Antibacterial agent 26 是一种抗菌化合物,是有效的DHFR 抑制剂(金黄色葡萄球菌DHFR Ki 为0.020 nM)。 | |||
T4208 |
Targocil
|
Antibacterial | Microbiology/Virology |
Targocil 是一种磷壁酸生物合成的抑菌抑制剂,可抑制甲氧西林敏感金黄色葡萄球菌 (MSSA) 和耐甲氧西林金黄色葡萄球菌 (MRSA) 的生长,对于 MRSA 和 MSSA 的MIC90值都为 2 μg/mL。 | |||
T40475 |
Ceftobiprole medocaril
BAL5788,头孢比普酯 |
Antibacterial | Microbiology/Virology |
Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素,对耐甲氧西林金黄色葡萄球菌具有活性。 | |||
T22387 |
NSC 55655
5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione |
Others | Others |
NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) 具有抗菌和抗氧化活性,抑制 B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi ,A. niger 和 C. albicans 的增殖,可用于糖尿病。 | |||
TQ0113 |
Iclaprim
艾拉普林,AR-100 |
Antibacterial; Antibiotic | Microbiology/Virology |
Iclaprim (AR-100) 是一种细菌二氢叶酸的选择性新型抑制剂, 可抑制金黄色葡萄球菌的生长, 其 MIC90值为 0.06 μg/mL。 | |||
T10586L |
BPH-1358
NSC50460 |
Others; Antibacterial | Microbiology/Virology; Others |
BPH-1358 (NSC-50460) 是一种人 FPPS 和 UPPS 抑制剂,IC50值分别为 1.8 μM 和 110 nM,对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。 | |||
T6638 |
Retapamulin
瑞他莫林,SB-275833 |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Retapamulin (SB-275833) 是一种能结合金黄色葡萄球菌和大肠杆菌核糖体的局部抗生素,Kd 为3 nM。 | |||
T77686 |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone
|
Antifungal | Microbiology/Virology |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone 具有广谱的抗真菌活性,对白色念珠菌、黑曲霉、铜绿假单胞菌、金黄色葡萄球菌等具有抑制作用。 | |||
T4105 |
AFN-1252
Debio 1452,API-1252 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
AFN-1252 (Debio 1452)是一种FabI 的高效抑制剂,能抑制金黄色葡萄球菌。 | |||
T23725L |
Amicoumacin A FA
Amicoumacin A FA(78654-44-1 Free base) |
Antibacterial | Microbiology/Virology |
Amicoumacin A FA 具有抗菌活性,抑制紫罗兰色杆菌和金黄色葡萄球菌,可用与研究微生物感染。 | |||
TP1663L |
CysHHC10 acetate
CysHHC10 acetate(1408311-03-4 free base) |
Antibacterial | Microbiology/Virology |
CysHHC10 acetate 对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性,对大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和表皮葡萄球菌的 MIC 分别为 10.1、20.2、2.5 和 1.3 mM。 | |||
T28229 |
Olanexidine hydrochloride
OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045 |
Antibacterial | Microbiology/Virology |
Olanexidine hydrochloride (OPB-2045 HCl) 对革兰氏阳性菌和革兰氏阴性菌具有杀菌活性。 Olanexidine hydrochloride 破坏金黄色葡萄球菌的膜完整性。 | |||
T0391 |
Linezolid
PNU-100766,雷奈佐利 |
MAO; Antibacterial; Antibiotic | Metabolism; Microbiology/Virology; Neuroscience |
Linezolid (PNU-100766) 是恶唑烷酮类合成抗生素,抑制细菌蛋白质合成的起始阶段,具有抗感染作用。 | |||
TN6672 |
Cyclo(L-Phe-L-Pro)
|
Free radical scavengers; COX; Antibacterial; Antifungal | Immunology/Inflammation; Microbiology/Virology; Neuroscience; oxidation-reduction |
Cyclo(L-Phe-L-Pro) 具有广谱抗菌和抗真菌活性。 Cyclo(L-Phe-L-Pro) 对耐甲氧西林金黄色葡萄球菌和棉子肠球菌具有活性。 | |||
T38137 |
3,5-Dimethylbenzaldehyde
|
Endogenous Metabolite; Antifungal | Metabolism; Microbiology/Virology |
3,5-Dimethylbenzaldehyde 具有广谱的抗菌活性,对枯草芽孢杆菌、白假丝酵母菌、大肠杆菌、铜绿假单胞菌、金黄色葡萄杆菌和肺炎链球菌具有抑制作用。 | |||
T11815 |
Lanopepden
GSK 1322322,GSK-1322322B,GSK-1322322J |
Antibiotic | Microbiology/Virology |
Lanopepden (GSK 1322322) 是一种有效的肽去甲酰酶抑制剂,抑制金黄色葡萄球菌,抑制 ATCC 29213 和 ATCC 25923 菌株,可用于研究肺炎、皮肤病和传染病。 | |||
TP1412 |
RNAIII-inhibiting peptide TFA
RNAIII-inhibiting peptide(TFA),L-酪氨酰-L-丝氨酰-L-脯氨酰-L-色氨酰-L-苏氨酰-L-天冬氨酰胺酰-L-苯丙氨酸 |
Antibacterial | Microbiology/Virology |
RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) 抑制肽(TFA)抑制金黄色葡萄球菌,对蜂窝织炎、角膜炎、化脓性关节炎、骨髓炎和乳腺炎等疾病有效。 | |||
T63390L |
(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA(171235-71-5 Free base) |
TNF | Apoptosis |
(S,S)-TAPI-1 FA是 TNF-α加工抑制剂,具有潜在抗炎作用,可阻断 TACE,可抑制 TNF-α 信号传导可用于研究金黄色葡萄球菌关节炎。 | |||
T1492 |
Gemifloxacin mesylate
LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate |
DNA gyrase; Topoisomerase; Antibacterial | DNA Damage/DNA Repair; Microbiology/Virology |
Gemifloxacin mesylate (Gemifloxacin mesylate) 是一种喹诺酮类口服广谱抗菌剂,可研究轻中度肺炎和慢性支气管炎的急性细菌性发作。 | |||
T50004 |
Phentolamine acetate
3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol acetic acid |
Others | Others |
Phentolamine acetate (3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol acetic acid) 是一种化合物,它在体外已被证明具有抗炎和抗癌特性,还被证明可以抑制某些细菌的生长,包括金黄色葡萄球菌。 | |||
T61042 |
TBT1
|
Antibacterial | Microbiology/Virology |
TBT1 是一种新型 MsbA 转运蛋白抑制剂,也是 MsbA ATPase 刺激剂,抑制脂多糖合成途径中ATP依赖性转运蛋白的合成。TBT1 具有抗菌活性,抑制沙门氏菌、铜绿假单胞菌、大肠杆菌和金黄色葡萄球菌,可用于研究细菌感染。 | |||
T4165 |
Delpazolid
LCB01-0371 |
Antibacterial; Antibiotic | Microbiology/Virology |
Delpazolid (LCB01-0371) 是一种恶唑烷酮类新型抗生素,能抑制MSSA 和MRSA 的生长,对它们的MIC90值都为 2 μg/mL。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5780 |
HYPOCRELLIN B
|
Apoptosis; Parasite; Antifungal | Apoptosis; Microbiology/Virology |
Hypocrellin B 是从真菌Hypocrella bambusae 和Shiraia bambusicola 中分离得到的一种感光颜料,可用于癌症光动力研究。它是一个凋亡诱导剂,还拥有抗菌和抗利什曼活性。 | |||
T3381 |
Lysionotin
岩豆素 |
Others | Others |
Lysionotin (Nevadensin) 是一种类黄酮,分离自黄花草药中。它可抑制 α-Toxin (一种成孔蛋白) 的表达,并在体内和体外针对金黄色葡萄球菌显示出显著的保护作用。它可用于研究由金黄色葡萄球菌引起的肺炎。 | |||
T5802 |
Stearyl glycyrrhetinate
|
Antiviral; Antibacterial | Immunology/Inflammation; Microbiology/Virology |
Stearyl glycyrrhetinate 是甘草提取物中的主要成分之一,具有抗菌作用,对金黄色葡萄球菌菌株的 MIC 大于 256 mg/L。 | |||
T2904 |
Sclareolide
香紫苏内酯,Norambreinolide |
Others; Antibacterial | Microbiology/Virology; Others |
Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物,具有抗菌和细胞毒性作用。 | |||
TN2730 |
2,5-Dihydroxybenzaldehyde
Gentisaldehyde,2,5-二羟基苯甲醛 |
Anti-infection; Antibacterial | Microbiology/Virology |
2,5-Dihydroxybenzaldehyde (Gentisaldehyde) 是一种天然抗微生物剂,可抑制Mycobacterium avium subsp. paratuberculosis 的生长。它还抑制金黄色葡萄球菌菌株,MIC50为 500 mg/L。 | |||
T4S1114 |
Dryocrassin ABBA
东北贯众素,Dryocrassin |
Influenza Virus; Antibacterial | Microbiology/Virology |
Dryocrassin ABBA (Dryocrassin) 是一种从苦参中提取的黄酮类天然产物,具有抗病毒和抗菌活性。它抑制树突状细胞的免疫刺激功能,延长同种异体皮肤移植成活率。 | |||
T1465 |
Mupirocin
Pseudomonic acid,莫匹罗星,BRL-4910A |
DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Mupirocin (BRL-4910A) 是从Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA,并抑制细菌蛋白和RNA 的合成起抗菌作用。 | |||
T1126 |
Penicillin V Potassium
青霉素V钾,Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt |
Antibacterial; Antibiotic | Microbiology/Virology |
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) 是一种有口服活性的抗生素。它可抑制链球菌,艰难梭菌和金黄色葡萄球菌的生长,可研究中耳炎,鼻窦炎,咽炎和扁桃体炎。 | |||
T8148 |
Mupirocin calcium hydrate
莫匹罗星钙,Mupirocin calcium |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的,一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA,并抑制细菌蛋白和RNA 的合成起到抗菌作用。 | |||
T8384 |
Gatifloxacin hydrochloride
AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride),加替沙星盐酸盐 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Gatifloxacin hydrochloride (AM-1155 hydrochloride) 是一种氟喹诺酮类抗生素,有广谱抗菌活性。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg/ml)和细菌 II 型拓扑异构酶(IC50=13.8 μg/ml) 。它在动物模型中,可研究细菌性结膜炎。 | |||
T37753 |
Aureusimine B
|
Cysteine Protease; Antibacterial | Microbiology/Virology; Proteases/Proteasome |
Aureusimine B 是一种钙蛋白酶抑制剂,由金黄色葡萄球菌生物膜产生,可能是金黄色葡萄球菌生物膜感染的潜在生物标志物。 | |||
TN5634 |
Aureusidin
Auresudidin,金鱼草素,Auresidin |
Antioxidant; Reactive Oxygen Species; Lipoxygenase | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Aureusidin (Auresidin) 具有抗氧化和脂氧合酶抑制活性,具有抗炎作用。 | |||
T13305 |
Viridicatol
|
Anti-infection; Antifungal | Microbiology/Virology |
Viridicatol 是从夹竹桃的内生真菌青霉菌属的发酵中分离出的一种喹诺酮类生物碱,对金黄色葡萄球菌有抗菌活性,MIC 值为 15.6 μg/mL。 | |||
TN1524 |
Continentalic acid
|
NOS; COX; Antibacterial; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Continentalic acid 是来自 Aralia continentalis 的,对金黄色葡萄球菌的 MIC 约为 8-16 µg/mL,包括对甲氧西林敏感的金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌标准菌株。 | |||
TN1527 |
(-)-Corynoxidine
Corynoxidine |
Antibacterial; AChE; Antifection | Microbiology/Virology; Neuroscience |
(-)-Corynoxidine 是一种源自 Stephania succifera 块茎的 AChE 抑制剂。 Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌具有不同程度的抗菌活性。 | |||
TJS0368 |
4-Phenyl-7,8-dihydroxycoumarin
7,8-二羟基-4-苯基香豆素,7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin |
Others | Others |
4-Phenyl-7,8-dihydroxycoumarin (7,8-Dihydroxy-4-phenylcoumarin) 是香豆素衍生物,可用于研究支气管扩张。 | |||
TN4943 |
Sanguisorbigenin
地榆皂苷元,Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid |
Antibacterial | Microbiology/Virology |
Sanguisorbigenin (Tomentosolic acid) 抑制耐甲氧西林金黄色葡萄球菌,是一种天然抗菌剂。 | |||
T8185 |
(+)-Viroallosecurinine
别一叶萩碱,Viroallosecurinine |
Antibacterial | Microbiology/Virology |
(+)-Viroallosecurinine (Viroallosecurinine) 是一种具有抗菌活性的天然生物碱,抑制Ps. Aeruginosa 和Staph. aureus,MIC 为 0.48 μg/mL。 | |||
T40646 |
Lipoteichoic acid
|
Complement System | Immunology/Inflammation |
Lipoteichoic acid 是 Staphylococcus aureus 细胞壁的聚合物,通过诱导 C3 和抑制 CD55 来激活补体系统,通过 IGF-1 途径减少脂肪沉积。 | |||
TN6746 |
(-)-TERPINEN-4-OL
|
Antibacterial | Microbiology/Virology |
(-)-TERPINEN-4-OL 可用作抗金黄色葡萄球菌的抗菌剂和抗生物膜剂。 | |||
TN1041 |
Quercimeritrin
槲皮素-7-O-葡萄糖苷,槲皮素-7-0-葡萄苷,Quercetin-7-O-beta-D-glucopyranoside |
Anti-infection; COX; NO Synthase | Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) 是分离自齿状苦艾叶中,具淀粉酶作用。 | |||
T13708 |
Glycol chitosan
羟乙基脱乙酰壳多糖,乙二醇壳聚糖 |
Antibacterial | Microbiology/Virology |
Glycol chitosan 是具有亲水性乙二醇支链的壳聚糖衍生物。它抑制大肠杆菌,金黄色葡萄球菌和肠炎链球菌的生长,MIC 值分别为 4 μg/mL,32 μg/m L 和 <0.5 μg/mL。它可增强 Glycine max Harosoy 63W 细胞的膜通透性和渗漏。 | |||
TN7094 |
Coreoside B
|
Antibacterial | Microbiology/Virology |
Coreoside B 是从coreoside 中分离出来的,对金黄色葡萄球菌和炭疽杆菌显示出较弱的抗菌活性。 | |||
T7335 |
2,3-Diaminopropionic acid
L-2,3-二氨基丙酸,L-2,3-Diaminopropionic acid |
Endogenous Metabolite | Metabolism |
2,3-Diaminopropionic acid (L-2,3-Diaminopropionic acid) 是一种神经毒性氨基酸 b-oxalyl-L-a, b-diaminopropionic acid 的代谢产物。 | |||
TN1204 |
2,3-Dehydrokievitone
2,3-脱氢维酮 |
Antifungal | Microbiology/Virology |
2,3-Dehydrokievitone 是一种从刺桐属植物 Erythrina sacleuxii 中提取的一种异黄酮,具有抗菌活性,可通过降低α-溶血素表达来对抗耐甲氧西林金黄色葡萄球菌感染。 | |||
TN2281 |
Sinapaldehyde
trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde,TRANS-3,5-二甲氧基-4-羟基肉桂醛,芥子醛 |
Antibacterial | Microbiology/Virology |
Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) 对耐甲氧西林的金黄色葡萄球菌和大肠杆菌有抗菌作用,MIC 值都为 128 μg/mL。 | |||
TN7242 |
5-Hydroxyvanillin
3,4-Dihydroxy-5-methoxybenzaldehyde |
Antifungal | Microbiology/Virology |
5-Hydroxyvanillin (3,4-Dihydroxy-5-methoxybenzaldehyde) 可从籼稻中就分离得到对金黄色葡萄球菌具有抑制作用,可用于治疗和预防骨质疏松症。 | |||
TN2898 |
Kaempferol-7,4'-dimethyl ether
3,5-Dihydroxy-4',7-dimethoxyflavone |
Antioxidant; Antifection | Microbiology/Virology; oxidation-reduction |
Kaempferol-7,4'-dimethyl ether 是从 Zingiber phillipseae 的根茎中分离得到的,对金黄色葡萄球菌和大肠杆菌具有抗氧化活性,MIC 分别为 200 和 225 μg/ml。 | |||
T21552 |
5-deoxy Thymidine
5'-脱氧胸苷,5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione |
Others | Others |
5-deoxy Thymidine (5'-Deoxythymidine) 是5'位被氢取代的胸苷形式。它对枯草芽孢杆菌和金黄色葡萄球菌的活性有效。 | |||
T3S2381 |
Perillene
3-Isohexenylfuran,紫苏烯,Perillen |
Others; Antibacterial | Microbiology/Virology; Others |
Perillene (3-Isohexenylfuran) 是促进肠蠕动的药物中的活性成分,它对金黄色葡萄球菌和大肠杆菌具有很强的抗药性。 | |||
T37267 |
Pachybasin
|
Antibacterial | Microbiology/Virology |
Pachybasin 是一种蒽醌真菌代谢物。 Pachybasin 对大肠杆菌、枯草芽孢杆菌、M. luteus、S. cerevisiae、C. albicans、A. niger 和 A. flavus 具有抗菌活性,MIC 值为 64.0 μg/mL,对金黄色葡萄球菌具有抗菌活性 和尖孢镰刀菌,MIC 值分别为 32.0 和 16.0 μg/mL。 | |||
T4S1616 |
Sanggenon D
Sanggenone D |
GABA Receptor; Antibiotic | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
Sanggenon D (Sanggenone D) 是来自桑白皮的小分子化合物,是GABA(A)受体调节剂,具有抗氧化抗菌活性,抑制乳腺癌细胞增殖,通过调节脂肪酸生物合成系统来抑制金黄色葡萄球菌的生长。 | |||
TN1905 |
Magnolioside
七叶苷甲基醚,6-甲氧基香豆素-7-0-BETA-D-吡喃葡萄糖苷 |
Antifection | Microbiology/Virology |
Magnolioside 是分离自Angelica gigas Nakai(Umbelliferae) 中,对谷氨酸诱导的毒性有显著的神经保护作用。 它显示出对金黄色葡萄球菌 CIP 53.154 的中等抗菌活性。它具有抗疟原虫活性,对氯喹敏感的恶性疟原虫菌株具有强烈的生长抑制作用。 | |||
TN1084 |
1,3,5,8-Tetrahydroxyxanthone
Desmethylbellidifolin,去甲基雏叶龙胆酮 |
Anti-infection | Microbiology/Virology |
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) 是一种天然黄酮,从 Gentianella acuta 中提取得到。它具有镇痉作用和抗炎作用。 | |||
TN1722 |
Hamamelitannin
|
Antifection | Microbiology/Virology |
Hamamelitannin 是分离自 Hamamelis virginiana 树皮的一种多酚,是群体感应抑制剂。它通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。 | |||
T8724 |
6-Methoxydihydrosanguinarine
|
Others | Others |
6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱,它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。 | |||
T70955 |
Vinaxanthone
SM-345431 |
Phospholipase; Antibacterial | Metabolism; Microbiology/Virology |
Vinaxanthone (SM-345431) 是一种从青霉菌中提取的小分子化合物,是一种具有选择性和有效性的 semaphorin3A、phospholipase C (PLC) 和 FabI 抑制剂,抑制semaphorin3A 和 FabI。Vinaxanthone 具有抗菌活性,阻止细胞内脂肪酸合成,抑制金黄色葡萄球菌的生长。 | |||
TN7224 |
2,2'-Dihydroxy chalcone
|
Antibacterial; Autophagy | Autophagy; Microbiology/Virology |
2,2'-Dihydroxy chalcone 是一种用 fMLP/CB 刺激的大鼠中性粒细胞释放β-葡糖醛酸酶(IC50=1.6±0.2μM)和溶菌酶(IC50=1.4±0.2μM)的有效抑制剂。2,2'-Dihydroxy chalcone 对大肠杆菌、福氏志贺氏菌、白葡萄球菌和金黄色葡萄球菌有抑菌活性。 | |||
T6S0525 |
Farrerol
|
ERK; p38 MAPK; Akt | Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling |
Farrerol 是一种杜鹃花的生物活性成分,具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。 | |||
TN1949 |
Moracin C
桑辛素 C,5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇 |
ROS; NO Synthase | Immunology/Inflammation |
Moracin C 是一种发现于Morus mesozygia、Morus alba var. multicaulis 中的天然化合物,是一种抗炎剂。Moracin C 可抑制细胞中的一氧化氮(NO)释放和LPS 激活的活性氧(ROS)。 | |||
T5S1981 |
alpha-Cyperone
(+)-α-Cyperone,α-香附酮,α-Cyperone |
Others; Endogenous Metabolite | Metabolism; Others |
alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。 | |||
TN3861 |
Dihydropinosylvin
山药 |
Anti-infection | Microbiology/Virology |
Dihydropinosylvin 是一种植物抗毒素,对枝孢枝孢菌、Botryodiplodia theobromae、黑曲霉和石化青霉具有抗真菌活性,对蜡状芽孢杆菌、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌也有很强的抗菌活性。双色高粱幼苗的种子和根伸长。 | |||
T6S2384 |
Poliumoside
|
Reductase | Endocrinology/Hormones; Metabolism |
Poliumoside 是从 Brandisia hancei 的茎和叶中分离出来的咖啡酰化的苯丙烷糖苷。Poliumoside 能够抑制晚期糖基化终产物的形成和大鼠晶状体醛糖还原酶,IC50分别为 19.69 和 8.47 μM。Poliumoside 具有抗炎和抗氧化特性。 | |||
TN2447 |
Isovalerylshikonin
|
Antibacterial | Microbiology/Virology |
Isovalerylshikonin 是太子参和紫草的天然产物。 | |||
TN3013 |
4,5-Dimethoxycanthin-6-one
Methylnigakinone |
P450; Antibacterial; PDE | Metabolism; Microbiology/Virology |
4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂(IC50 : 1.7 μM, Ki : 2.6 μM),对环磷酸腺苷(cAMP)磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性,对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。 | |||
T6873 |
Lauric Acid
月桂酸,Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Lauric Acid (Dodecylic acid) 是一种有抗菌活性的中链脂肪酸,对P. acnes,S.aureus 和S. epidermidis 的 EC50值分别为 2,6,4 μg/mL。 | |||
TN1991 |
Norchelerythrine
|
Antifection | Microbiology/Virology |
Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner with the EC50 of 62.67 ppm. | |||
TN3216 |
(3R)-7,4’-Dihydrohomoisoflavanone
7,4'-Dihydroxyhomoisoflavanone |
Antibacterial | Microbiology/Virology |
(3R)-7,4’-Dihydrohomoisoflavanone 是一种天然化合物,对金黄色葡萄球菌和耐甲氧西林金黄色葡萄菌(MRSA)都具有强大的抗菌性能。 | |||
TC0017 |
Haplopine
|
Tyrosinase; Antifection | Microbiology/Virology; Proteases/Proteasome |
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells. | |||
TN2760 |
2-Hydroxy-1,8-cineole
|
Antifection | Microbiology/Virology |
1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescens) .<BR/> | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03580 |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Staphylococcus aureus neutral proteinase,aur,Zinc m... |
Staphylococcus aureus | E. coli |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177. | |||
TMPH-03575 |
Sortase A Protein, S. aureus, Recombinant (His)
Surface protein sorting A,srtA,Sortase A |
Staphylococcus aureus | E. coli |
Sortase A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is Q2FV99. | |||
TMPH-03561 |
lsdB Protein, S. aureus, Recombinant (His & SUMO)
Fur-regulated protein B,Iron-regulated surface determinant p... |
Staphylococcus aureus | E. coli |
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization. Promotes also resistance to hydrogen peroxide and killing by neutrophils. lsdB Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is ... | |||
TMPH-03557 |
HlgC Protein, S. aureus, Recombinant (His)
hlgC,Gamma-hemolysin component C |
Staphylococcus aureus | P. pastoris (Yeast) |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.6 kDa and the accession number is Q7A3S2. | |||
TMPH-03555 |
HlgB Protein, S. aureus, Recombinant (His)
H-gamma-I,hlgB,Gamma-hemolysin component B,H-gamma-1 |
Staphylococcus aureus | P. pastoris (Yeast) |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgB Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 36.1 kDa and the accession number is P0A075. | |||
TMPH-03518 |
ACP Protein, S. aureus, Recombinant (GST)
acpP,Fatty acid synthase acyl carrier protein,Acyl carrier p... |
Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001. | |||
TMPH-03563 |
MCAT Protein, S. aureus, Recombinant (His)
fabD,Malonyl CoA-acyl carrier protein transacylase |
Staphylococcus aureus | P. pastoris (Yeast) |
MCAT Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 35.6 kDa and the accession number is Q5HGK3. | |||
TMPH-03519 |
ACP Protein, S. aureus, Recombinant (His)
Cytosolic-activating factor,Fatty acid synthase acyl carrier... |
Staphylococcus aureus | P. pastoris (Yeast) |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001. | |||
TMPH-03527 |
FtsZ Protein, S. aureus, Recombinant (His)
ftsZ,Cell division protein FtsZ |
Staphylococcus aureus | E. coli |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. FtsZ Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The ... | |||
TMPH-03525 |
Cap5A Protein, S. aureus, Recombinant (His)
Capsular polysaccharide type 5 biosynthesis protein cap5A,ca... |
Staphylococcus aureus | E. coli |
Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator. Cap5A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P95695. | |||
TMPH-03526 |
Cap8A Protein, S. aureus, Recombinant (His)
MAGEB2,MAGE XP-2 antigen,DAM6,MAGE-B2 antigen,Melanoma-assoc... |
Staphylococcus aureus | E. coli |
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Cap8A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is O15479. | |||
TMPH-03572 |
SplB Protein, S. aureus, Recombinant (His & Myc)
splB,Serine protease SplB |
Staphylococcus aureus | E. coli |
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln. SplB Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is A7X3Q8. | |||
TMPH-03516 |
NPTase Protein, S. aureus, Recombinant (His & SUMO)
30 kDa neutral phosphatase |
Staphylococcus aureus | E. coli |
Highly cationic enzyme that can bind human or rat immunoglobulins as well as serum albumin, and could therefore be involved in post-infectious sequelae. NPTase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.7 kDa and the accession number is P21222. | |||
TMPH-03566 |
Peptide deformylase Protein, S. aureus, Recombinant (His)
Polypeptide deformylase,def,Peptide deformylase |
Staphylococcus aureus | P. pastoris (Yeast) |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is P68826. | |||
TMPH-03568 |
Phospholipase C Protein, S. aureus, Recombinant (His)
hlb,Beta-hemolysin,Phospholipase C,Beta-toxin,Sphingomyelina... |
Staphylococcus aureus | P. pastoris (Yeast) |
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine. Phospholipase C Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 3... | |||
TMPH-03550 |
EsxA Protein, S. aureus, Recombinant (His & SUMO)
esxA,Type VII secretion system extracellular protein A |
Staphylococcus aureus | E. coli |
Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity. EsxA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.... | |||
TMPH-03578 |
SCIN Protein, S. aureus, Recombinant (His & Myc)
scn,Staphylococcal complement inhibitor |
Staphylococcus aureus | E. coli |
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses. SCIN Protein, S. aureus, ... | |||
TMPH-03558 |
LytM Protein, S. aureus, Recombinant (His)
Autolysin LytM,Glycyl-glycine endopeptidase LytM,lytM |
Staphylococcus aureus | E. coli |
Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan. LytM Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is O33599. | |||
TMPH-03574 |
SdrE Protein, S. aureus, Recombinant (His)
sdrE,Serine-aspartate repeat-containing protein E |
Staphylococcus aureus | E. coli |
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity. Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation. SdrE Protein, S. aureus, Recombin... | |||
TMPH-03564 |
MCAT Protein, S. aureus, Recombinant (His & SUMO)
Malonyl CoA-acyl carrier protein transacylase,fabD |
Staphylococcus aureus | E. coli |
MCAT Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q5HGK3. | |||
TMPH-03553 |
HlgA Protein, S. aureus, Recombinant (His & Myc)
H-gamma-II,H-gamma-2,Gamma-hemolysin component A,hlgA |
Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgA Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is P0A073. | |||
TMPH-03565 |
MazF Protein, S. aureus, Recombinant (His)
Toxin MazF,mRNA interferase MazF,mazF,Endoribonuclease MazF |
Staphylococcus aureus | E. coli |
Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE. MazF Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession... | |||
TMPH-03577 |
Staphopain B Protein, S. aureus, Recombinant (GST)
Staphopain B,sspB,Staphylopain B,Staphylococcal cysteine pro... |
Staphylococcus aureus | E. coli |
Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin. Staphopain B Protein, S.... | |||
TMPH-03540 |
Enterotoxin type B Protein, S. aureus, Recombinant (GST)
entB,Enterotoxin type B,SEB |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type B Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST ... | |||
TMPH-03571 |
WalK Protein, S. aureus, Recombinant (His & Myc)
walK,Sensor protein kinase WalK |
Staphylococcus aureus | E. coli |
WalK Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.3 kDa and the accession number is A6QD58. | |||
TMPH-03570 |
IsaA Protein, S. aureus, Recombinant (His & Myc)
Probable transglycosylase IsaA,Immunodominant staphylococcal... |
Staphylococcus aureus | E. coli |
Is able to cleave peptidoglycan. IsaA Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.8 kDa and the accession number is P60157. | |||
TMPH-03521 |
MecA Protein, S. aureus, Recombinant (His & SUMO)
Adapter protein MecA,mecA |
Staphylococcus aureus | E. coli |
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P60186. | |||
TMPH-03573 |
SplD Protein, S. aureus, Recombinant (His & Myc)
Serine protease SplD,splD |
Staphylococcus aureus | E. coli |
SplD Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.5 kDa and the accession number is Q2FXC5. | |||
TMPH-03560 |
lsdA Protein, S. aureus, Recombinant (His & Myc)
Iron-regulated surface determinant protein A,Staphylococcal ... |
Staphylococcus aureus | E. coli |
lsdA Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.1 kDa and the accession number is Q6GA85. | |||
TMPH-03533 |
Ddl Protein, S. aureus, Recombinant (His & Myc)
ddl,D-alanylalanine synthetase,D-Ala-D-Ala ligase,D-alanine-... |
Staphylococcus aureus | E. coli |
Cell wall formation. Ddl Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.7 kDa and the accession number is P63891. | |||
TMPH-03520 |
ACP Protein, S. aureus, Recombinant (His & SUMO)
acpP,Cytosolic-activating factor,Fatty acid synthase acyl ca... |
Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001. | |||
TMPH-03536 |
FabI Protein, S. aureus, Recombinant (His & SUMO)
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI,fabI,NAD... |
Staphylococcus aureus | E. coli |
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism. FabI Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.0 kDa and the accession number is Q6GI75. | |||
TMPH-03569 |
IcaB Protein, S. aureus, Recombinant (His & Myc)
Intercellular adhesion protein B,Poly-beta-1,6-N-acetyl-D-gl... |
Staphylococcus aureus | E. coli |
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions. IcaB Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular ... | |||
TMPH-03522 |
Alpha-hemolysin Protein, S. aureus, Recombinant (His)
Alpha-toxin,Alpha-HL |
Staphylococcus aureus | P. pastoris (Yeast) |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity. | |||
TMPH-03537 |
Enterotoxin type A Protein, S. aureus, Recombinant (His)
Enterotoxin type A,SEA,entA |
Staphylococcus aureus | E. coli |
Enterotoxin type A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is P0A0L2. | |||
TMPH-03576 |
Staphopain A Protein, S. aureus, Recombinant (His & Myc)
Staphopain A,Staphylopain A,sspP,Staphylococcal cysteine pro... |
Staphylococcus aureus | E. coli |
Staphopain A Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.4 kDa and the accession number is P81297. | |||
TMPH-03556 |
HlgC Protein, S. aureus, Recombinant (E. coli, His)
hlgC,Gamma-hemolysin component C |
Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.6 kDa and the accession number is Q7A3S2. | |||
TMPH-03523 |
Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)
Alpha-HL,Alpha-toxin |
Staphylococcus aureus | E. coli |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity. | |||
TMPH-03545 |
Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO)
Enterotoxin type E,SEE,entE |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. | |||
TMPH-03551 |
Exfoliative toxin A Protein, S. aureus, Recombinant (His)
eta,Epidermolytic toxin A,Exfoliative toxin A |
Staphylococcus aureus | E. coli |
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS). | |||
TMPH-03559 |
Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated
sbi,Immunoglobulin-binding protein Sbi |
Staphylococcus aureus | E. coli |
Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis. Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The... | |||
TMPH-03515 |
ClfA Protein, S. aureus (strain MSSA476), Recombinant
clfA,Clumping factor A,Fibrinogen-binding protein A,Fibrinog... |
Staphylococcus aureus | E. coli |
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. | |||
TMPH-03524 |
KAS III Protein, S. aureus, Recombinant (His & Myc)
3-oxoacyl-[acyl-carrier-protein] synthase 3,3-oxoacyl-[acyl-... |
Staphylococcus aureus | E. coli |
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au... | |||
TMPH-03539 |
Enterotoxin type B Protein, S. aureus, Recombinant (His)
Enterotoxin type B,SEB,entB |
Staphylococcus aureus | P. pastoris (Yeast) |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. | |||
TMPH-03549 |
Enterotoxin type H Protein, S. aureus, Recombinant (His)
Enterotoxin type H,SEH,entH |
Staphylococcus aureus | P. pastoris (Yeast) |
Enterotoxin type H Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.1 kDa and the accession number is P0A0M0. | |||
TMPH-03535 |
Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
DHFR,Dihydrofolate reductase,folA |
Staphylococcus aureus | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.6 kDa and the accession number is P99079. | |||
TMPH-03531 |
ClfA Protein, S. aureus (strain COL), Recombinant (His)
Fibrinogen-binding protein A,clfA,Clumping factor A,Fibrinog... |
Staphylococcus aureus | P. pastoris (Yeast) |
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. ClfA Protein, S. aureus (strain COL), Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 38.0 kDa and the accession number is Q5HHM8. | |||
TMPH-03567 |
Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)
Peptide deformylase,def,Polypeptide deformylase |
Staphylococcus aureus | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is P68826. | |||
TMPH-03544 |
Enterotoxin type D Protein, S. aureus, Recombinant (His & SUMO)
entD,SED,Enterotoxin type D |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. In addition, induces B-cell proliferation and differentiation in the presence of T-cells. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type D P... | |||
TMPH-03579 |
TSST-1 Protein, S. aureus, Recombinant (His & SUMO)
Toxic shock syndrome toxin-1,tst |
Staphylococcus aureus | E. coli |
Responsible for the symptoms of toxic shock syndrome. TSST-1 Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.9 kDa and the accession number is P06886. | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37250 |
Cefazolin-13C2,15N
Cefazolin-13C2,15N |
||
Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin by GC- or LC-MS. Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml). It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50... | |||
T69995 |
Chlorhexidine-d8 HCl
|
||
Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC... | |||
T36021 |
Flumequine-13C3
Flumequine-13C3 |
||
Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae(MICs = 1-100 μg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3In vivo, fl... |