|
TMPH-00010
|
MMP-14 Protein, Human, Recombinant (His & SUMO)
Membrane-type-1 matrix metalloproteinase,MMP14,Membrane-type...
|
Human
|
E. coli
|
|
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to... |
|
TMPY-00539
|
GSTA1 Protein, Human, Recombinant (His)
glutathione S-transferase alpha 1,GTH1,GST2,glutathione S-tr...
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Human
|
HEK293 Cells
|
|
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno... |
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TMPY-02543
|
PCNA Protein, Human, Recombinant (His)
ATLD2,proliferating cell nuclear antigen
|
Human
|
Baculovirus Insect Cells
|
|
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic... |
|
TMPK-01146
|
LGMN Protein, Human, Recombinant (His)
AI746452,Legumain,LGMN1,Prsc1,AEP,LGMN,AU022324
|
Human
|
HEK293 Cells
|
|
Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD. |
|
TMPH-01294
|
EDNRA Protein, Human, Recombinant (His)
ET-A,Endothelin-1 receptor,hET-AR,ETA-R,ETRA,EDNRA,ETA
|
Human
|
P. pastoris (Yeast)
|
|
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
|
TMPY-02511
|
PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)
LRP,PTP α/PTPRA Protein, Human, Recombinant (aa 174-793, His...
|
Human
|
Baculovirus Insect Cells
|
|
PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTPRA could promote the cell cycle progression through stimulating the c-Src signaling pathways. The PTPRA gene, which encodes the protein RPTP-alpha, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and anima... |
|
TMPY-02497
|
S100A15 Protein, Mouse, Recombinant (His & MBP)
S100a17l1,Gm1020,S100a15a,AY465109,S100A7f,S100A7L1,S100 cal...
|
Mouse
|
E. coli
|
|
Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesti... |
|
TMPJ-00064
|
OX40L/TNFSF4 Protein, Human, Recombinant (His)
TNFSF4,Glycoprotein Gp34,TAX transcriptionally-activated gly...
|
Human
|
HEK293 Cells
|
|
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L binds to OX40 (CD134), a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proli... |
|
TMPH-02253
|
TPM2 Protein, Human, Recombinant (His)
TPM2,Tropomyosin-2,Tropomyosin beta chain,Beta-tropomyosin
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. |
|
TMPH-01528
|
IHH Protein, Human, Recombinant (His)
HHG-2,IHH,Indian hedgehog protein
|
Human
|
E. coli
|
|
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP). |
|
TMPH-02106
|
SH3PXD2A Protein, Human, Recombinant (His & Myc)
SH3PXD2A,SH3 multiple domains protein 1,SH3 and PX domain-co...
|
Human
|
E. coli
|
|
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide. |
|
TMPH-03587
|
GspB Protein, S. gordonii, Recombinant (GST)
Serine-rich adhesin for platelets,Serine-rich repeat protein...
|
Streptococcus gordonii
|
E. coli
|
|
Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA. Plays a positive role in biofilm formation, possibly by self-association via the basic region (BR). GspB Protein, S. gordonii, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 68.5 kDa and the accession number is Q939N5. |
|
TMPH-02300
|
RAD23A Protein, Human, Recombinant (His)
UV excision repair protein RAD23 homolog A,RAD23A
|
Human
|
E. coli
|
|
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucle... |
|
TMPY-01346
|
Psoriasin/S100A7 Protein, Human, Recombinant
S100 calcium binding protein A7,PSOR1,S100A7c
|
Human
|
E. coli
|
|
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role... |
|
TMPH-02177
|
Tapasin Protein, Human, Recombinant (His & Myc)
TAP-binding protein,Tapasin,TAPBP,TAP-associated protein,NGS...
|
Human
|
E. coli
|
|
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). Tapasin Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.4 kDa and the accession number is O15533. |
|
TMPK-00742
|
PRL-3/PTP4A3 Protein, Human, Recombinant (His)
PRL-R,PRLR,PRL3,PTP4A3,PRL-3
|
Human
|
E. coli
|
|
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) plays an important role in the tumorigenesis and metastasis of multiple tumors. |
|
TMPJ-01213
|
ASXL1 Protein, Human, Recombinant (GST)
Putative Polycomb group protein ASXL1,Additional sex combs-l...
|
Human
|
E. coli
|
|
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 t... |
|
TMPH-02337
|
Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO)
hfb1,Hydrophobin-1,Hydrophobin I
|
Hypocrea jecorina
|
E. coli
|
|
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.5 kDa and the accession number is P52754. |
|
TMPH-03613
|
NblA Protein, Synechococcus elongatus, Recombinant (His & Myc)
nblA,Phycobilisome degradation protein NblA
|
Synechococcus elongatus
|
E. coli
|
|
Involved in phycobilisome (PBS) degradation during nutrient deprivation. May mark the PBS for degradation by covalent association with PBS components or may disrupt the PBS via ionic interactions. NblA Protein, Synechococcus elongatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.5 kDa and the accession number is P35087. |
|
TMPH-03371
|
Transferrin Protein, Rat, Recombinant (His & KSI)
Tf,Beta-1 metal-binding globulin,Liver regeneration-related ...
|
Rat
|
E. coli
|
|
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Transferrin Protein, Rat, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight ... |
|
TMPH-03213
|
TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)
Tropomyosin alpha-1 chain,TPM1,Alpha-tropomyosin,Tropomyosin...
|
Rabbit
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular w... |
|
TMPH-02999
|
uL2 Protein, Mycobacterium tuberculosis, Recombinant (His)
rplB,50S ribosomal protein L2,Large ribosomal subunit protei...
|
Mycobacterium tuberculosis
|
E. coli
|
|
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. uL2 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.7 kDa and the accession ... |
|
TMPH-03634
|
GRA3 Protein, Toxoplasma gondii, Recombinant (His)
P30,GRA3,Dense granule protein 3
|
Toxoplasma gondii
|
E. coli
|
|
Direct host-parasite interaction occurs at the cytoplasmic faces of the parasitophorous vacuole membrane (PVM) and the host endoplasmic reticulum (ER) membrane via GRA3 and host CAMLG association. Direct insertion of GRA3 ER retrieval motif into the host ER membrane contributes to the host ER recruitment to the PVM. GRA3 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 10.8 kDa and the accession number is ... |
|
TMPK-01132
|
PRL-1/PTP4A1 Protein, Human, Recombinant (His)
PTPCAAX1,PRL1,PRL-1,PTP(CAAXI),PTP4A1
|
Human
|
E. coli
|
|
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is a key molecule that activates tyrosine phosphorylation, which is important for cancer progression and metastasis. |
|
TMPH-02252
|
TPM3 Protein, Human, Recombinant (GST)
Gamma-tropomyosin,Tropomyosin alpha-3 chain,Tropomyosin-3,TP...
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
|
TMPK-00705
|
MASP2 Protein, Human, Recombinant (His)
MAP19,sMap,MASP-2,MASP1P1
|
Human
|
E. coli
|
|
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population. |
|
TMPH-02209
|
TRAF5 Protein, Human, Recombinant (His & SUMO)
TRAF5,RING finger protein 84,TNF receptor-associated factor ...
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Human
|
E. coli
|
|
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. |
|
TMPK-01019
|
EPHA5 Protein, Mouse, Recombinant (His)
TYRO4,HEK7,EHK-1,EphA5,EK7,BSK,Rek7,EHK1,TYRO4HEK7CEK7
|
Mouse
|
HEK293 Cells
|
|
The aim of the present study was to evaluate ephrin type-A receptor 5 (EphA5) expression and its clinicopathological significance in gastric cancer. Gastric cancer tissues were analyzed by immunohistochemistry. The association between EphA5 expression and clinicopathological parameters, human epidermal growth factor receptor 2 (HER2) status and Ki-67 proliferation index was statistically analyzed. |
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TMPH-02185
|
TEP1 Protein, Human, Recombinant (His)
p80 telomerase homolog,TEP1,Telomerase protein component 1,p...
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Human
|
E. coli
|
|
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC. TEP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weigh... |
|
TMPH-01285
|
EEF1D Protein, Human, Recombinant (His)
Elongation factor 1-delta,EF1D,EF-1-delta,EEF1D,Antigen NY-C...
|
Human
|
E. coli
|
|
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). |
|
TMPK-00502
|
PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
PDI5,HL-60,PAD,PADI5,Protein-arginine deiminase type-4,HL60 ...
|
Cynomolgus
|
E. coli
|
|
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biot... |
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TMPK-00057
|
IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-10,GVHDS,Interleukin-10,白介素,白细胞介素,MGC126451,CSIF,MGC12645...
|
Human
|
HEK293 Cells
|
|
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor (IL10R)-deficient mice develop spontaneous intestinal inflammation. Similarly, patients with deleterious mutations in IL10, IL10RA, or IL10RB present with severe enterocolitis within the first months of life. IL-10 Protein, Human, Rec... |
|
TMPY-01657
|
SUV420H2 Protein, Human, Recombinant (His & GST)
suppressor of variegation 4-20 homolog 2 (Drosophila),KMT5C
|
Human
|
E. coli
|
|
Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-lysine methyltransferase family and Suvar4-2 subfamily. SUV42H2 is a histone methyltransferase that specifically trimethylates 'Lys-2' of histone H4. H4 'Lys-2' trimethylation represents a specific tag for epigenetic transcriptional repression. SUV42H2 mainly functions in pericentr... |
|
TMPJ-00053
|
PRL-2 Protein, Human, Recombinant (His)
HU-PP-1,Protein tyrosine phosphatase type IVA 2,OV-1,PTP4A2,...
|
Human
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E. coli
|
|
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeran... |
|
TMPJ-00345
|
IGF2BP-2 Protein, Human, Recombinant (His)
IGF-II mRNA-Binding Protein 2,IGF2 mRNA-Binding Protein 2,He...
|
Human
|
E. coli
|
|
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replicat... |
|
TMPH-03212
|
TPM1 Protein, Rabbit, Recombinant (His & Myc)
TPM1,Alpha-tropomyosin,Tropomyosin alpha-1 chain,Tropomyosin...
|
Rabbit
|
Baculovirus Insect Cells
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 3... |
|
TMPK-01087
|
Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)
ApoA-V,Apolipoprotein A-V,Rap3,Apoa5,Apo-AV,Apolipoprotein A...
|
Mouse
|
E. coli
|
|
APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological roles of apoAV have been recently elucidated, such as control of chylomicron production in the intestine and TG accumulation in adipose tissue.The key role of APOA5 in TG metabolism has been largely shown through genetic studies in association with either severe or moderate hyper... |
|
TMPH-03432
|
ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)
mRNA transport-defective protein 7,Acetyl-CoA carboxylase,Fa...
|
Saccharomyces cerevisiae
|
E. coli
|
|
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol... |
|
TMPY-03600
|
TPM4 Protein, Human, Recombinant (His)
tropomyosin 4,HEL-S-108,TPM4
|
Human
|
HEK293 Cells
|
|
TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 is expressed in cardiac tissue and platelets. It is highly expressed in the platelets of hypertensive patients. TPM4 plays a central role, in association with the troponin complex, in the calcium-dependent regulation of vertebrate striated muscle contraction. Smo... |
|
TMPJ-00421
|
CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
T-cell activation antigen CD27,Tumor necrosis factor recepto...
|
Human
|
HEK293 Cells
|
|
CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It pla... |
|
TMPH-02105
|
ASH2L Protein, Human, Recombinant (His & SUMO)
ASH2-like protein,ASH2L,ASH2L1,Set1/Ash2 histone methyltrans...
|
Human
|
E. coli
|
|
Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May p... |
|
TMPY-02398
|
TLE3 Protein, Human, Recombinant (aa 484-772, GST)
transducin-like enhancer of split 3,GRG3,ESG3,HsT18976,ESG
|
Human
|
E. coli
|
|
The association between high TLE3 expression and a favorable response to taxane-containing chemotherapy regimens was validated in patients with non-serous ovarian cancer. That TLE3 expression may serve as a marker of chemosensitivity in taxane-treated patients with non-serous histologies. Transducin-like enhancer of Split3 (TLE3) serves as a transcriptional corepressor during cell differentiation and shows multiple roles in different kinds of cancers. TLE3 repressed CRC proliferation partly thro... |
|
TMPY-04566
|
CAMKV Protein, Human, Recombinant (His & GST)
1G5,VACAMKL,CaM kinase-like vesicle-associated
|
Human
|
Baculovirus Insect Cells
|
|
CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase family. CAMKV contains oneprotein kinase domain. It is predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. CAMKV may be associated with vesicular structures. It does not appear to have detectable kinase activity. ... |
|
TMPK-00501
|
PADI4 Protein, Cynomolgus, Recombinant (His)
Protein-arginine deiminase type-4,HL60 PAD,PAD,PDI5,PADI5,PA...
|
Cynomolgus
|
E. coli
|
|
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expres... |
|
TMPY-03461
|
GABARAPL2 Protein, Human, Recombinant (His)
GATE16,ATG8,ATG8C,GEF-2,GATE-16,GEF2,GABA(A) receptor-associ...
|
Human
|
E. coli
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GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. |
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TMPY-03434
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BMF Protein, Human, Recombinant (His)
Bcl2 modifying factor
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Human
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E. coli
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BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular d... |
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TMPH-03431
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ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)
Acetyl-CoA carboxylase,ACC,Fatty acid synthetase 3,mRNA tran...
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Saccharomyces cerevisiae
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E. coli
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Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m... |
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TMPH-02732
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IFNAR2 Protein, Mouse, Recombinant (His)
Ifnar2,Type I interferon receptor 2,Interferon alpha/beta re...
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Mouse
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P. pastoris (Yeast)
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Associates with IFNAR1 to form the plasma membrane receptor in the type I interferon signaling pathway. Directly involved in signal transduction through its association with the TYR kinase JAK1. Involved in interferon-mediated STAT1, STAT2 and STAT3 activation.; May be potent inhibitors of type I IFN receptor activity.; May be potent inhibitors of type I IFN receptor activity. IFNAR2 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.8 ... |
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TMPJ-00793
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TPM3 Protein, Human, Recombinant
Tropomyosin α-3 Chain,γ-Tropomyosin,hTM5,Tropomyosin Alpha-3...
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Human
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E. coli
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Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are... |
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TMPK-00056
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IL-10 Protein, Human, Recombinant (His & Avi)
MGC126450,白细胞介素,GVHDS,B-TCGF,IL10A,白介素,TGIF,CSIF,IL-10,Inter...
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Human
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HEK293 Cells
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Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor (IL10R)-deficient mice develop spontaneous intestinal inflammation. Similarly, patients with deleterious mutations in IL10, IL10RA, or IL10RB present with severe enterocolitis within the first months of life. IL-10 Protein, Human, Rec... |
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