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Search Results for " utilization "

Targets Recommended: ATPase Antibiotic Parasite

41

抑制剂 & 化合物

10

天然产物

4

化合物库

14

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L1510	核受体化合物库		531 compounds
	531 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L6230	苗药化合物库		534 compounds
	534种苗族特色药材的天然产物分子，可用于高通量和高内涵筛选
L5700	精选片段库		246 compounds
	246 个片段小分子的独特集合，可用于基于片段的筛选和药物发现（FBDD）；
DO1200	药物靶点库		53200 compounds
	数量多，含53200种小分子化合物，是高通量筛选的有力工具；

化合物库

核受体化合物库

Cat.No: L1510

Compounds: 531

苗药化合物库

Cat.No: L6230

Compounds: 534

精选片段库

Cat.No: L5700

Compounds: 246

药物靶点库

Cat.No: DO1200

Compounds: 53200

Cat. No.	Product Name	Target	Signaling Pathways
T1137	Clorsulon 克洛索隆,L631529,MK401,氯舒隆	ATPase; Antibiotic; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	Clorsulon (L631529) 是一种具有口服活性的灭虫试剂，用于犊牛和羊的肝吸虫感染。它也是 3-磷酸甘酸酯和 ATP 的竞争性抑制剂，可抑制成熟肝片吸虫对葡萄糖的利用以及乙酸和丙酸的形成。
T63806	CFTR corrector 8	CFTR	Membrane transporter/Ion channel
	CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic disorder primarily affecting the lungs and digestive system [1].
T2608	CHIR-98014 CHIR 98014,CT98014,CHIR98014	FGFR; GSK-3; Src; S6 Kinase	Angiogenesis; MAPK; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	CHIR-98014 (CT98014) 是有效的，细胞通透的GSK-3抑制剂，可抑制 GSK-3α (IC50:0.65 nM) 和 GSK-3β (IC50:0.58 nM) 的活性，对 cdc2 和 erk2 的作用较弱。
T0988	Trimetazidine dihydrochloride 盐酸曲美他嗪,Yoshimilon,Kyurinett,Vastarel F	Autophagy; Fatty Acid Synthase	Autophagy; Metabolism
	Trimetazidine dihydrochloride (Vastarel F) 是细胞保护性抗缺血剂，也用作缺血性心脏病或心绞痛的血管扩张剂，具有抗氧化，抗炎，抗伤害和胃保护作用。它可通过抑制脂肪酸代谢提高心肌葡萄糖利用率。
T37577	Glycogen Phosphorylase Inhibitor	Others	Others
	Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic glycogenolysis in vivo. Glycogen phosphorylase inhibitor has been used to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells.
T40774	7-Deaza-7-propargylamino-3'-azidomethyl-dATP	Others	Others
	7-Deaza-7-propargylamino-3'-azidomethyl-dATP, an analog of deoxyadenosine triphosphate (dATP), finds extensive utilization in next-generation sequencing (NGS).
T61530	PBENZ-DBRMD	Others	Others
	PBENZ-DBRMD, a powerful iodothyronine deiodinase type 3 (DIO3) inhibitor, exhibits anti-proliferative activity and promotes apoptosis. This compound holds potential for utilization in cancer research [1].
T61876	Sipagladenant	Others	Others
	Sipagladenant (Compound I) is an orally active inverse agonist targeting the adenosine receptor A2A [1]. It possesses potential for utilization in research pertaining to frontal lobe dysfunction [2].
T39187	Gliadin p31-43 Gliadin p31-43
	Gliadin p31-43, an undigested peptide derived from gliadin, prompts an innate immune response in the intestine and disrupts endocytic trafficking. Moreover, its utilization in celiac disease research has proven beneficial.
T61743	PPARγ agonist 2	Others	Others
	PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ. It exhibits significant potential for utilization in metabolic disease research [1].
T76105	Alcohol oxidase	Others	Others
	Alcohol oxidase 是甲醇利用途径的功能酶，能够从酵母的过氧化物酶体中分离得到。
TP1259	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153
	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) functions as a substrate for insulin receptor tyrosine kinase. This substance effectively binds to insulin and exhibits the potential for utilization in scientific research and medical applications.
T29029	U-0521	Others	Others
	U-0521, an inhibitor of catechol-O-methyltransferase (COMT), enhances the availability and utilization of levodopa in the brain.
T83167	Adipokinetic Hormone (AKH) (24-32), locust TFA
	Adipokinetic Hormone (AKH) (24-32), locust (TFA)，是从蝗虫心脏分离的一种神经激素，调节飞行过程中的脂质利用。
T14479	Azido-PEG8-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Azido-PEG8-NHS ester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl/ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].
T40973	MDNI-caged-L-glutamate MDNI-caged-L-glutamate,MDNI-glu	Others	Others
	MDNI-glu is a photosensitive derivative of L-glutamate, a major excitatory amino acid, that is biologically inert. It demonstrates improved utilization of incident light.
T19211	BM152054	Others	Others
	BM152054 是一种有效的 PPARγ配体，可以通过加强胰岛素作用来诱导外周组织对葡萄糖的利用。
T17902	Nutlin-C1-amido-PEG4-C2-N3 E3 ligase Ligand-Linker Conjugates 48,MDM2 Ligand-Linker Conjugates 1	Others	Others
	Nutlin-C1-amido-PEG4-C2-N3 is a novel compound that functions as a ligand-linker conjugate for the E3 ligase. It is a synthesized molecule incorporating the MDM2 ligand derived from Nutlin 3, and a 4-unit PEG linker. This compound is specifically designed for utilization in PROTAC technology.
T27324	FK614 FK 614,ATx-08-001,ATx-08001,FK-614	Others	Others
	FK-614 is a selective agonist of peroxisome proliferator-activated receptor gamma. FK-614 improves peripheral glucose utilization while decreases hepatic insulin extraction in alloxan-induced diabetic dogs.
T38674	yGsy2p-IN-H23 yGsy2p-IN-H23	Others	Others
	yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds precisely within the uridine diphosphate glucose (UDPG) binding pocket of yGsy2p. Its utilization in research primarily focuses on studying glycogen storage diseases (GSDs).
T22444	Trimetazidine	Others	Others
	Trimetazidine, an anti-ischemic (anti-anginal) metabolic agent, could improve myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose
T41083	pNP-ADPr pNP-ADPr,ADP-ribose-pNP	Others	Others
	pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose) polymerase (PARP) enzymes.
T17915	Thalidomide-O-amido-PEG3-C2-NH2 Cereblon Ligand-Linker Conjugates 3,E3 Ligase Ligand-Linker Conjugates 14	Others	Others
	Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is an E3 ligase ligand-linker conjugate which is designed using Thalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is synthesized specifically for utilization in PROTAC technology.
T15871	m-PEG4-Boc	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	m-PEG4-Boc is a cleavable 4-unit polyethylene glycol (PEG) linker, widely employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, m-PEG4-Boc serves as a PEG-based PROTAC linker, enabling its utilization in the synthesis of PROTACs [2].
T61538	Antiparasitic agent-10	Others	Others
	Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Schistosoma mansoni. As a result, this compound holds significant potential for utilization in Schistosomiasis research as a viable treatment option [1].
T84550	AMC Arachidonoyl Amide AMC-AA	Others	Others
	Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates...
T15455	RGH-5526 GYKI-11679	Others	Others
	RGH-5526是一种新型的抗高血压药。它引起下丘脑去甲肾上腺素（NA）周转（利用）增加，下丘脑去甲肾上腺素能神经元活性的增加可能导致外周交感神经活性的降低，从而显著降低血压。
T39066	H-D-Phe-Pip-Arg-pNA hydrochloride S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride
	H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.
T69622	Ritivixibat	Others	Others
	Ritivixibat为回肠胆汁酸转运蛋白(IBAT)抑制剂，同时也是胆汁酸调节剂，主要适用于心血管疾病、脂肪酸代谢及葡萄糖利用障碍、胃肠道和肝脏疾病的研究。
T79289	Antiproliferative agent-27	Apoptosis	Apoptosis
	Antiproliferative agent-27 (化合物 11) 作为一种有效的抗增殖剂，可显著降低肿瘤细胞的集落数量并诱导细胞凋亡，显示出在癌症研究中的应用潜力。
T37004	Estradiol 3-sulfate 17β-Glucuronide (potassium salt)	Others	Others
	Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com...
T69685	AGPS-IN-2i	MMP	Proteases/Proteasome
	AGPS-IN-2i 是一种高效且具有很高亲和力的烷基甘油磷酸酯合成酶抑制剂的，可控制着细胞中醚脂的利用和代谢，降低了醚类脂质水平和细胞迁移率，促进癌细胞的增殖和运动。AGPS-IN-2i 在 PC-3和 MDA-MB-231癌细胞中测试时通过调节 E-cadherin、Snail 和 MMP2的表达水平，特异性地损害了上皮向间质转化（EMT）。AGPS-IN-2i 对癌细胞增殖具有抑制作用。
T75363	Fluorescein Di-β-D-Glucuronide
	Fluorescein Di-β-D-Glucuronide 作为一款荧光探针，以其非侵入性的优势被广泛应用于裸鼠肠道细菌β-葡萄糖醛酸酶（βG）活性成像研究中。该探针通过成像技术有效揭示了肠道细菌β-葡萄糖醛酸酶在体内外的活性，进而为特定细菌β-葡萄糖醛酸酶抑制剂的药效学评估提供了重要工具。
T73228	Artonin E 5'-Hydroxymorusin	Others	Others
	Artonin E (5'-Hydroxymorusin) 是一种已知的异戊二烯化类黄酮，可以诱导细胞凋亡 (apoptosis)，使细胞周期停滞在S 期。Artonin E 可以通过线粒体通路失调诱导抗增殖作用，可以用于癌症研究。
T73610	Lipoprotein lipase	Others	Others
	Lipoprotein lipase 是来自于脂肪组织、心肌和骨骼肌、胰岛和巨噬细胞的多功能酶。Lipoprotein lipase 促进正常脂蛋白代谢、组织特异性底物的输送和利用。Lipoprotein lipase 催化脂质在血液循环的限速步骤。
T35839	3-Iodothyronamine (hydrochloride)	Others	Others
	3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and cardiac output. It has also been reported to function in controlling lipid and glucose utilization, hormonal secretion, and neuronal function, and has been considered for use in chemically-...
T83165	Adipokinetic hormone (Manduca sexta) Manse-AKH
	Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta) 是昆虫肽类激素，能强烈诱导促脂肪/高海藻素反应，但不具备糖原动员功能，亦不能在脂肪体内有效储存及利用糖原。
T74188	3-Cyanovinylcarbazole phosphoramidite	Others	Others
	3-Cyanovinylcarbazole phosphoramidite 是一种抗病毒活性分子，可以抑制病毒 DNA 的合成。该化合物中的修饰核苷是通过在 C-3 位用氰基修饰核糖核苷酸而合成的，可作为 DNA 合成的磷酸酰胺。
T78043	S-(2-Carboxyethyl)-L-cysteine S-Carboxyethylcysteine
	S-(2-Carboxyethyl)-L-cysteine（S-羧乙基半胱氨酸）为一非蛋白质(改性)硫氨基酸，在Acacia种子中被发现。该化合物能够影响大鼠对种子蛋白质的利用效率，并可能抑制由蛋氨酸诱发的大鼠生长速度，同时对大鼠血浆氨基酸水平产生不利影响。
T78872	CTL-06	Others	Others
	CTL-06是一种Fatty Acid Synthase (FASN)抑制剂，具有3 μM的IC50，能够诱发细胞凋亡。CTL-12导致细胞周期在Sub-G1/S期停滞，并增加caspase-9和凋亡标志物Bax的表达，减少抗凋亡标志物Bcl-xL的表达。此外，CTL-12通过抑制脂肪酸的从头合成，剥夺肿瘤细胞代谢所需，主要用于乳腺癌和结直肠癌的研究。
T37347	6'-Sialyllactose Sodium Salt 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose	Others	Others
	6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne...

化合物

Cat.No: T1137

Synonym: 克洛索隆,L631529,MK401,氯舒隆

Target: ATPase, Antibiotic, Parasite

CFTR corrector 8

Cat.No: T63806

Target: CFTR

Cat.No: T2608

Synonym: CHIR 98014,CT98014,CHIR98014

Target: FGFR, GSK-3, Src, S6 Kinase

Trimetazidine dihydrochloride

Cat.No: T0988

Synonym: 盐酸曲美他嗪,Yoshimilon,Kyurinett,Vastarel F

Target: Autophagy, Fatty Acid Synthase

Glycogen Phosphorylase Inhibitor

Cat.No: T37577

Target: Others

7-Deaza-7-propargylamino-3'-azidomethyl-dATP

Cat.No: T40774

Target: Others

Cat.No: T61530

Target: Others

Cat.No: T61876

Target: Others

Cat.No: T39187

Synonym: Gliadin p31-43

PPARγ agonist 2

Cat.No: T61743

Target: Others

Alcohol oxidase

Cat.No: T76105

Target: Others

[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)

Cat.No: TP1259

Synonym: [pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153

Cat.No: T29029

Target: Others

Adipokinetic Hormone (AKH) (24-32), locust TFA

Cat.No: T83167

Azido-PEG8-NHS ester

Cat.No: T14479

Target: Others, ADC Linker

MDNI-caged-L-glutamate

Cat.No: T40973

Synonym: MDNI-caged-L-glutamate,MDNI-glu

Target: Others

Cat.No: T19211

Target: Others

Nutlin-C1-amido-PEG4-C2-N3

Cat.No: T17902

Synonym: E3 ligase Ligand-Linker Conjugates 48,MDM2 Ligand-Linker Conjugates 1

Target: Others

Cat.No: T27324

Synonym: FK 614,ATx-08-001,ATx-08001,FK-614

Target: Others

Cat.No: T38674

Synonym: yGsy2p-IN-H23

Target: Others

Cat.No: T22444

Target: Others

Cat.No: T41083

Synonym: pNP-ADPr,ADP-ribose-pNP

Target: Others

Thalidomide-O-amido-PEG3-C2-NH2

Cat.No: T17915

Synonym: Cereblon Ligand-Linker Conjugates 3,E3 Ligase Ligand-Linker Conjugates 14

Target: Others

Cat.No: T15871

Target: Others, ADC Linker

Antiparasitic agent-10

Cat.No: T61538

Target: Others

AMC Arachidonoyl Amide

Cat.No: T84550

Synonym: AMC-AA

Target: Others

Cat.No: T15455

Synonym: GYKI-11679

Target: Others

H-D-Phe-Pip-Arg-pNA hydrochloride

Cat.No: T39066

Synonym: S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride

Cat.No: T69622

Target: Others

Antiproliferative agent-27

Cat.No: T79289

Target: Apoptosis

Estradiol 3-sulfate 17β-Glucuronide (potassium salt)

Cat.No: T37004

Target: Others

Cat.No: T69685

Target: MMP

Fluorescein Di-β-D-Glucuronide

Cat.No: T75363

Cat.No: T73228

Synonym: 5'-Hydroxymorusin

Target: Others

Lipoprotein lipase

Cat.No: T73610

Target: Others

3-Iodothyronamine (hydrochloride)

Cat.No: T35839

Target: Others

Adipokinetic hormone (Manduca sexta)

Cat.No: T83165

Synonym: Manse-AKH

3-Cyanovinylcarbazole phosphoramidite

Cat.No: T74188

Target: Others

S-(2-Carboxyethyl)-L-cysteine

Cat.No: T78043

Synonym: S-Carboxyethylcysteine

Cat.No: T78872

Target: Others

6'-Sialyllactose Sodium Salt

Cat.No: T37347

Synonym: 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7480	1-Undecanol 十一醇,Undecyl alcohol,1-Hendecanol	Others	Others
	1-Undecanol (1-Hendecanol) 是水果、黄油、鸡蛋和熟猪肉等许多食品中的天然产物，用作调味成分。它也可通过微生物从 2-tridecanol 中产生。
T13752	L-(+)-Arabinose	Endogenous Metabolite	Metabolism
	L-(+)-Arabinose 能够选择性抑制肠道蔗糖酶，并抑制因蔗糖摄入而导致的血浆葡萄糖提高。
T21383	D-Thyroxine Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine	Others	Others
	D-Thyroxine (Dextroxin) 是一种甲状腺激素，对 TSH 的分泌具有抑制作用，可用于研究高胆固醇血症。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T10940	D-Mannoheptulose	Others	Others
	D-mannoheptose is the main non-structural carbohydrate in avocado. D-mannoheptose is a specific inhibitor of D-glucose phosphorylation. D-mannoheptose can prevent the release of insulin and the utilization of carbohydrates in rats.
TN3966	Epicatechin pentaacetate	NOS	Immunology/Inflammation
	Epicatechin pentaacetate is a phenolic compound from the V. mullaha fruit extracts, the utilization of V. mullaha fruit as functional food with prospective pharmaceutical, nutraceuticals and cosmeceutical properties.
TN4581	Moracin D	c-Myc; TNF; COX; Antifection	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
T73465	Goitrin L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone	Others	Others
	Goitrin ((S)-Goitrin) 为芥子油苷-黑芥子酶反应产物，有效抑制甲状腺过氧化物酶并阻碍碘在甲状腺的利用。此外，该化合物亦展现出对抗流感病毒(H1N1)的活性。
TN1617	Ergosta-4,6,8(14),22-tetraen-3-one	BCL; Caspase; p53	Apoptosis; Proteases/Proteasome
	Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of man
TN4582	Moracin T	c-Myc; COX	Cell Cycle/Checkpoint; Immunology/Inflammation; Neuroscience
	Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermo

天然产物

Cat.No: T7480

Synonym: 十一醇,Undecyl alcohol,1-Hendecanol

Target: Others

L-(+)-Arabinose

Cat.No: T13752

Target: Endogenous Metabolite

Cat.No: T21383

Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine

Target: Others

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

D-Mannoheptulose

Cat.No: T10940

Target: Others

Epicatechin pentaacetate

Cat.No: TN3966

Target: NOS

Cat.No: TN4581

Target: c-Myc, TNF, COX, Antifection

Cat.No: T73465

Synonym: L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone

Target: Others

Ergosta-4,6,8(14),22-tetraen-3-one

Cat.No: TN1617

Target: BCL, Caspase, p53

Cat.No: TN4582

Target: c-Myc, COX

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) CIMT1,PPARγ,GLM1,PPARgamma,PPARG1,PPARG2,NR1C3,peroxisome pr...	Human	Baculovirus Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. Peroxisome proli...
TMPY-02481	ACOX1 Protein, Human, Recombinant (His) PALMCOX,ACOX,SCOX,acyl-CoA oxidase 1, palmitoyl	Human	Baculovirus Insect Cells
	Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a...
TMPH-00599	LDCC Protein, E. coli, Recombinant (His) ldcC,Constitutive lysine decarboxylase	E. coli	E. coli
	Plays a role in lysine utilization by acting as a lysine decarboxylase.
TMPH-00786	BtuD Protein, Halobacterium salinarum, Recombinant (His) Vitamin B12-transporting ATPase,btuD,Cobalamin import ATP-bi...	Halobacterium salinarum	E. coli
	Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPH-01563	IAPP Protein, Human, Recombinant (His) IAPP,Diabetes-associated peptide,Insulinoma amyloid peptide,...	Human	P. pastoris (Yeast)
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
TMPH-00787	BtuD Protein, Halobacterium salinarum, Recombinant Vitamin B12-transporting ATPase,Cobalamin import ATP-binding...	Halobacterium salinarum	E. coli
	Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPH-01562	IAPP Protein, Human, Recombinant (GST) Insulinoma amyloid peptide,IAPP,Islet amyloid polypeptide,Am...	Human	E. coli
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.4 kDa and the accession number is P10997.
TMPH-03046	TBP1 Protein, MenB, Recombinant (His & Myc) Transferrin-binding protein 1,Transferrin-binding protein A,...	MenB	E. coli
	Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Binds both apo- and holo-TF, via the TF C-terminus.
TMPY-01427	AACS Protein, Human, Recombinant (His) SUR-5,acetoacetyl-CoA synthetase,ACSF1	Human	Baculovirus Insect Cells
	Acetoacetyl-CoA Synthetase (AACS) is a novel cytosolic ketone body (acetoacetate)-specific ligase. The AACS in adipose tissue plays an important role in utilizing ketone body for the fatty acid-synthesis during adipose tissue development. It had been improved that Acetoacetyl-CoA Synthetase is an essential enzyme for the synthesis of fatty acid and cholesterol from ketone bodies, was found to be highly expressed in mouse adipose tissue, and GC box and C/EBPs motif were crucial for AACS promoter ...
TMPJ-00463	BDH2 Protein, Human, Recombinant (His) Oxidoreductase UCPA,Dehydrogenase/Reductase SDR Family Membe...	Human	E. coli
	3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.
TMPY-04375	Casein Kinase 1 alpha Protein, Human, Recombinant (GST) CKIa,casein kinase 1, alpha 1,casein kinase 1, α1,CK1a,Casei...	Human	Baculovirus Insect Cells
	Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are use...
TMPH-03371	Transferrin Protein, Rat, Recombinant (His & KSI) Tf,Beta-1 metal-binding globulin,Liver regeneration-related ...	Rat	E. coli
	Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Transferrin Protein, Rat, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight ...
TMPY-04475	RFK Protein, Human, Recombinant (His) riboflavin kinase,RIFK	Human	E. coli
	Flavokinase is a member of the transferases family, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. Flavokinase is an essential enzyme that catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN), an obligatory step in vitamin B2 utilization and flavin cofactor synthesis. It has been proposed that TNF, through the activation of the flavokinase gene, enhances the incorporation of FAD in NADP...
TMPY-04394	Glucokinase Protein, Human, Recombinant glucokinase (hexokinase 4),HXKP,MODY2,FGQTL3,LGLK,HKIV,GLK,H...	Human	E. coli
	Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but ...

重组蛋白

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02575

Species: Human

Expression System: Baculovirus Insect Cells

ACOX1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02481

Species: Human

Expression System: Baculovirus Insect Cells

LDCC Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00599

Species: E. coli

Expression System: E. coli

BtuD Protein, Halobacterium salinarum, Recombinant (His)

Cat.No: TMPH-00786

Species: Halobacterium salinarum

Expression System: E. coli

IAPP Protein, Human, Recombinant (His)

Cat.No: TMPH-01563

Species: Human

Expression System: P. pastoris (Yeast)

BtuD Protein, Halobacterium salinarum, Recombinant

Cat.No: TMPH-00787

Species: Halobacterium salinarum

Expression System: E. coli

IAPP Protein, Human, Recombinant (GST)

Cat.No: TMPH-01562

Species: Human

Expression System: E. coli

TBP1 Protein, MenB, Recombinant (His & Myc)

Cat.No: TMPH-03046

Species: MenB

Expression System: E. coli

AACS Protein, Human, Recombinant (His)

Cat.No: TMPY-01427

Species: Human

Expression System: Baculovirus Insect Cells

BDH2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00463

Species: Human

Expression System: E. coli

Casein Kinase 1 alpha Protein, Human, Recombinant (GST)

Cat.No: TMPY-04375

Species: Human

Expression System: Baculovirus Insect Cells

Transferrin Protein, Rat, Recombinant (His & KSI)

Cat.No: TMPH-03371

Species: Rat

Expression System: E. coli

RFK Protein, Human, Recombinant (His)

Cat.No: TMPY-04475

Species: Human

Expression System: E. coli

Glucokinase Protein, Human, Recombinant

Cat.No: TMPY-04394

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0094	Trimetazidine-d8 Dihydrochloride
	Trimetazidine-d8 Dihydrochloride 是 Trimetazidine Dihydrochloride 的氘代化合物。Trimetazidine Dihydrochloride 的 CAS 号为 13171-25-0。Trimetazidine dihydrochloride 是细胞保护性抗缺血剂，也用作缺血性心脏病或心绞痛的血管扩张剂，具有抗氧化，抗炎，抗伤害和胃保护作用。它可通过抑制脂肪酸代谢提高心肌葡萄糖利用率。

同位素标记化合物

Trimetazidine-d8 Dihydrochloride

Cat.No: TMIJ-0094

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