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Search Results for " type-4 "

Targets Recommended: Others

132

抑制剂 & 化合物

30

天然产物

2

化合物库

3

TargetMol 试剂盒

163

重组蛋白

13

同位素标记化合物

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Cat. No.	Product Name
L7300	钾通道分子库		152 compounds
	152 种钾通道相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；

化合物库

钾通道分子库

Cat.No: L7300

Compounds: 152

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0109	Magrose Beads IDA-Nickel His-tag 蛋白纯化磁珠 IDA-Ni	Suspension in bottle	蛋白纯化
C0110	Magrose Beads IDA-Cobalt His-tag 蛋白纯化磁珠 IDA-Co	Suspension in bottle	蛋白纯化
C0111	Magrose Beads NTA-Nickel (Ultra-suspension) His-tag 蛋白纯化磁珠 NTA-Ni	Suspension in bottle	蛋白纯化

TargetMol 试剂盒

His-tag 蛋白纯化磁珠 IDA-Ni

Cat.No: C0109

His-tag 蛋白纯化磁珠 IDA-Co

Cat.No: C0110

His-tag 蛋白纯化磁珠 NTA-Ni

Cat.No: C0111

Cat. No.	Product Name	Target	Signaling Pathways
T14496	BAMB-4 ITPKA-IN-C14	Others	Others
	BAMB-4 (ITPKA-IN-C14) 是一种新型的膜渗透型ITPKA 抑制剂，在ADP-Glo 实验中的IC50值为37uM。
T3184	Kevetrin hydrochloride Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride	Mdm2; p53	Apoptosis
	Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) 是一种小分子，是肿瘤抑制蛋白 p53 的激活剂，具有潜在的抗肿瘤活性。
T12302	OMDM-1 (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide	Endogenous Metabolite	Metabolism
	OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) 是有效选择性的代谢稳定 anandamide 细胞摄取抑制剂，Ki=为2.4 μM。
T5354	IRAK4-IN-7 CA-4948	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂，口服有活性。它可用于研究癌症以及炎症疾病。
T2923	Apremilast 阿普斯特,CC-10004,阿普司特	Apoptosis; TNF; PDE	Apoptosis; Metabolism
	Apremilast (CC-10004) 是一种口服有效的磷酸二酯酶 4 抑制剂，IC50为 74 nM。它抑制脂多糖释放TNF-α，IC50为 104 nM。
T7369L	Gemigliptin Tartrate(911637-19-9 free base) 吉格列汀酒石酸盐,LC15-0444 tartrate	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Gemigliptin Tartrate (LC15-0444 tartrate) 是一种选择性的，可逆的，竞争性的二肽基肽酶 4 (DPP-4) 抑制剂，对于人重组 DPP-4 的IC50=10.3 nM。Gemigliptin tartrate 具有很强的抗糖基化活性，能够用于晚期糖基化终产物相关的糖尿病并发症的研究。
T6146	Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK; Autophagy; TGF-beta/Smad	Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
	Dorsomorphin dihydrochloride (BML-275 2HCl) 是一种 AMPK 抑制剂 (Ki=109 nM)，具有选择性和 ATP 竞争性。Dorsomorphin dihydrochloride 可以抑制 BMP I 型受体 ALK2、ALK3 和 ALK6。Dorsomorphin dihydrochloride 可诱导自噬，具有抗肿瘤活性。
TP1878L	PACAP 1-38 acetate	PACAP	GPCR/G Protein
	PACAP 1-38 acetate 是一种垂体腺苷酸环化酶激活多肽 (PACAP) 类似物。它与 PACAP I 型受体 (IC50 = 4 nM) 和 PACAP II 型 VIP2 受体 (IC50 = 1 nM) 结合，但不与 PACAP II 型 VIP1 受体结合。
T4462	Roflumilast N-oxide	PDE	Metabolism
	Roflumilast N-oxide 是一种 PDE 4 型抑制剂。
T29019	TS-021 TS021,TS 021,TS-021 Free	DPP-4	Proteases/Proteasome
	TS-021 是一种具有选择性的二肽基肽酶 4 (DPP-4) 抑制剂，具有抗糖尿病活性，可用于研究2 型糖尿病。
T26698	AZ044	PI4K	PI3K/Akt/mTOR signaling
	AZ044是 III 型磷脂酰肌醇-4-激酶α -亚型(PI4KIIIalpha)的有效选择性抑制剂。
T12710	Retagliptin Phosphate SP 2086,瑞格列汀磷酸盐	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Retagliptin Phosphate (SP 2086) 是一种选择性、竞争性、口服活性的二肽基肽酶 4 (DPP-4) 抑制剂。Retagliptin phosphate 能够用于 2 型糖尿病 (T2DM) 的研究。
T64377	AGI-41998 tautomers	Others	Others
	AGI-41998 tautomers 是pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one 的互变异构体。pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one 是S-adenosylmethionine synthase isoform type-2抑制剂, IC50= 0.022μM。
T9906	Ipilimumab	Others	Others
	Ipilimumab 是全人类单克隆抗体 IgG1κ，能够抗 CTLA-4。其中CTLA-4是一种由活化的 T 细胞产生的免疫抑制分子。
T67837	(3S)-GSK-F1 PI4KA inhibitor-F1	PI4K	PI3K/Akt/mTOR signaling
	(3S)-GSK-F1是一种选择性PI4KIIIα抑制剂，pIC50=8.3。
T3476	JI-101 CGI-1842,JI 101	VEGFR; PDGFR; Ephrin Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	JI-101 (CGI-1842) 是一种有口服活性的多靶点激酶抑制剂，能够抑制VEGFR2，PDGFRβ和EphB4，具有抗癌作用。
T2296	Trelagliptin succinate 曲格列汀琥珀酸盐,琥珀酸曲格列汀,SYR-472 succinate,SYR472	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Trelagliptin succinate (SYR-472 succinate) 是一种有效的，具有口服活性的DPP-4抑制剂，IC50=4 nM。它可以改善体内血糖控制，能够用于2 型糖尿病(T2DM) 的研究。
T7133	Anagliptin SK-0403,阿拉格列汀	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Anagliptin (SK-0403) 是一种选择性的二肽酰肽酶 4 抑制剂，IC50=3.8 nM，对 DPP-8/9 的选择性相对较弱，IC50分别为 68 和 60 nM。
T2677	Crenolanib ARO 002,CP-868596	FLT; PDGFR; Autophagy	Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
	Crenolanib (ARO 002) 是一种口服生物可利用的 III 型酪氨酸激酶抑制剂，抑制 FLT3和 PDGFRα/β的 IC50分别为 4、11和 3.2 nM。
T24905	TT01001 TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate	Mitochondrial Metabolism	Metabolism
	TT01001 (Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate) 是 mitoNEET 的选择性激动剂，通过改善线粒体功能障碍来减少氧化应激损伤和神经元凋亡。 TT01001可用于治疗 II 型糖尿病的研究。
T68053	Denagliptin GW823093	DPP-4	Proteases/Proteasome
	Denagliptin是一种小分子二肽基肽酶IV（DPP-4）抑制剂，可用于治疗内分泌于代谢疾病，可用于研究2型糖尿病。
T60248	4-Aminobenzamidine dihydrochloride p-Aminobenzamidine dihydrochloride	Serine Protease	Proteases/Proteasome
	4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) 是一种强胰蛋白酶 (trypsin)抑制剂，也是一种相对较弱的尿激酶型纤溶酶原激活剂 (uPA) 抑制剂 (Ki=82 μM)。4-Aminobenzamidine 可抑制 SCID 小鼠体内前列腺肿瘤的生长。
T16164	MY-5445 N-(3-chlorophenyl)-4-phenylphthalazin-1-amine	PDE	Metabolism
	MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) 是特异性的 cGMP 磷酸二酯酶 PDE5抑制剂，其 Ki=1.3 μM。它是一种 ABCG2转运蛋白调节剂，具有抗增殖活性。它能抑制人血小板凝集。
T6900	MS023	Histone Methyltransferase	Chromatin/Epigenetic
	MS023 是一种有效的、选择性的、细胞活性的 I 型 PRMT 抑制剂，对 PRMT1、PRMT3、PRMT4、PRMT6和 PRMT8的 IC50分别为 30、119、83、4 和 5 nM。
T38507	Renzapride BRL 24924	5-HT Receptor	GPCR/G Protein; Neuroscience
	Renzapride (BRL 24924) 是一种混合 5-羟色胺 4 型（5-HT4）激动剂和 5-HT3 受体拮抗剂。Renzapride 可用于研究以便秘为主的肠易激综合征（C-IBS）。
T10776	CFTR corrector 4	CFTR	Membrane transporter/Ion channel
	CFTR corrector 4是一种高效且可口服的囊性纤维化跨膜电导调节剂 (CFTR)，是一种有效的 (R，R) 型活性对映体。CFTR corrector 4 可以增加细胞表面的 CFTR 水平，是用来研究囊性纤维化的潜在化合物。
T3188	RE-640	CCR; Parasite	Immunology/Inflammation; Microbiology/Virology
	NSC-5844 (RE-640) 是 4-氨基喹啉衍生物，起抗肿瘤和抗疟疾作用。
T12730	RIPK1-IN-4	RIP kinase	Apoptosis; NF-κB
	RIPK1-IN-4 是有效的 II 型激酶受体相互作用蛋白1 (RIP1) 激酶抑制剂，并且与 DL1-out 无活性形式的 RIP1 结合。RIPK1-IN-4抑制 RIP1 和 ADP-Glo 激酶，IC50 分别是 16 nM 和 10 nM。
T1766	Empagliflozin BI 10773,恩格列净	SGLT	GPCR/G Protein
	Empagliflozin (BI 10773) 是一种 SGLT-2 抑制剂 (IC50=3.1 nM)，具有有效的和选择性，对 SGLT-1/4/5/6 的选择性高 300 倍以上。Empagliflozin 可用于治疗二型糖尿病。
T1291	Cisapride 西沙必利,西沙比利,Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase	Potassium Channel; 5-HT Receptor; HER	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors
	Cisapride (R 51619) 是一种5-HT4受体激动剂，还是 hERG 抑制剂。它可作用于肠道中的血清素受体，促进肠道蠕动，增加胃排空并减少食管反流。
T22324	Ensartinib hydrochloride Ensartinib dihydrochloride,X-396 dihydrochloride	Others; Trk receptor; c-Met/HGFR; ALK	Angiogenesis; Others; Tyrosine Kinase/Adaptors
	Ensartinib hydrochloride (X-396 dihydrochloride) 是双重的 ALK/MET 抑制剂，IC50分别 <0.4 nM 和 0.74 nM。
T11157L	EGFR-IN-1 hydrochloride	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-1 hydrochloride 是 L858R/T790M 突变体 EGFR 的不可逆特异性抑制剂，选择性是野生型 EGFR 的 100 倍。 EGFR-IN-1 hydrochloride 在 H1975 细胞和突变体 HCC827 细胞中表现出有效的抗肿瘤和抗增殖活性，IC50 分别为 4 和 28 nM。
T0242	Sitagliptin 西他列汀,MK0431,西格列汀	Proteasome; DPP-4; Autophagy	Autophagy; Proteases/Proteasome; Ubiquitination
	Sitagliptin (MK0431) 是一种有效的 DPP4抑制剂，在 Caco-2 细胞中，IC50值为 19 nM。它是一种新型口服降糖药，可单独使用或与二甲双胍或噻唑烷二酮联合用于治疗 2 型糖尿病。
T50077	m-Nisoldipine 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate	Others	Others
	m-Nisoldipine (3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) 是一种二氢吡啶类钙通道阻滞剂，尼索地平的衍生物，阻断心脏和平滑肌细胞中的 L-型钙通道，用于治疗高血压和心绞痛。
T8970	ML162	Ferroptosis; GPX; Glutathione Peroxidase	Apoptosis; Metabolism; oxidation-reduction
	ML162 是一种共价谷胱甘肽过氧化物酶 4 抑制剂。它选择性抑制表达突变 RAS 癌基因的细胞系。
T1024	Roflumilast 罗氟司特,B9302-107,BYK 20869,APTA 2217,BY 217	PDE; RSV	Metabolism; Microbiology/Virology
	Roflumilast (APTA 2217) 是一种口服的长效 4 型磷酸二酯酶抑制剂 (PDE4)，具有抗炎和潜在的抗肿瘤活性，作用于PDE4A1，PDEA4，PDEB1和PDEB2，IC50分别为 0.7，0.9，0.7 和 0.2 nM。
T67896	CB2R/FAAH modulator-1	Cannabinoid Receptor; FAAH	GPCR/G Protein; Metabolism; Neuroscience
	CB2R/FAAH modulator-1是一种大麻素2型受体(CB2R)激动剂，同时也是脂肪酸酰胺水解酶(FAAH)抑制剂（IC50=4 μM），可减少促炎和增加抗炎细胞因子的产生，常用于炎症研究。对 CB2R 和 CB1R 的Kis 分别为14.8 nM 和241.3 nM。
T6611	NSC697923 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran	E1/E2/E3 Enzyme	Ubiquitination
	NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct mechanisms. In p53 wild-type NB cells, NSC-697923 promotes the nuclear importation of p53, thereby triggering cell death. Meanwhile, in p53 mutant NB cells, NSC-697923 activates the JNK-mediated apoptotic pathway, leading to cell death. Additionally, NSC-697923 inhibits DNA damage ...
T16345	NS13001 N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine	Potassium Channel	Membrane transporter/Ion channel
	NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) 是口服有效的 SK 通道选择性正向变构调节剂。NS13001 对 SK2 和 SK3 通道的 EC50分别为 1.8 μM 和 0.14 μM。NS13001 在脊髓小脑共济失调 2 型和其他小脑共济失调方面具有研究价值。
T36935	PKUMDL-LC-101-D04 GPX4-Activator-1d4,PKUMDL-LC-101-D04	GPX	oxidation-reduction
	PKUMDL-LC-101-D04是一种高效的谷胱甘肽过氧化物酶4（GPX4）的异位激活剂，是一种铁死亡的调节剂。当在无细胞试验中使用浓度为20 μM 时，GPX4活性增加到对照水平的150%；在野生型而非Gpx4-/-小鼠胚胎成纤维细胞(MEF)提取物中使用浓度为61 μM 时，GPX4活性增加到对照水平的150%。PKUMDL-LC-101-D04（200 μM）能减少胆固醇过氧化氢诱导的MEF 死亡。
T26132	RS 14203 RS-14203,RS14203	Others	Others
	RS 14203 is a selective type 4 phosphodiesterase (PDE4) inhibitor.
T28520	Retagliptin SP-2086,SP2086,SP 2086	Others	Others
	Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.
T26777	Besigliptin Tosylate SHR 117887,SHR-117887,SHR117887	Others	Others
	Besigliptin Tosylate, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
T26857	BMS-767778	Others	Others
	BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
T15163	DPC-681 DPH-153893	Others	Others
	DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1).
T20815	4-Chloroloratadine 4-Chloro loratadine,Loratadine specified impurity C	Others	Others
	4-Chloroloratadine is an impurity of Loratadine, a nonsedating-type histamine H1-receptor.
T26941	Camegliptin RO-4876904-001,R1579,RG1579,RO-4876904,R-1579,RG-1579	Others	Others
	Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.
T11420	GLUT4 activator 1	Others	Others
	GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).
T11499	GSK726701A	Others	Others
	GSK726701A is a new type of prostaglandin E2 receptor 4 (EP4) partial agonist (pEC50: 7.4).
T27598	Imigliptin Dihydrochloride Imigliptin	Others	Others
	Imigliptin Dihydrochloride, a selective dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type II diabetes.

化合物

Cat.No: T14496

Synonym: ITPKA-IN-C14

Target: Others

Kevetrin hydrochloride

Cat.No: T3184

Synonym: Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride

Target: Mdm2, p53

Cat.No: T12302

Synonym: (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide

Target: Endogenous Metabolite

Cat.No: T5354

Synonym: CA-4948

Target: IRAK

Cat.No: T2923

Synonym: 阿普斯特,CC-10004,阿普司特

Target: Apoptosis, TNF, PDE

Gemigliptin Tartrate(911637-19-9 free base)

Cat.No: T7369L

Synonym: 吉格列汀酒石酸盐,LC15-0444 tartrate

Target: Proteasome, DPP-4

Dorsomorphin dihydrochloride

Cat.No: T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

PACAP 1-38 acetate

Cat.No: TP1878L

Target: PACAP

Roflumilast N-oxide

Cat.No: T4462

Target: PDE

Cat.No: T29019

Synonym: TS021,TS 021,TS-021 Free

Target: DPP-4

Cat.No: T26698

Target: PI4K

Retagliptin Phosphate

Cat.No: T12710

Synonym: SP 2086,瑞格列汀磷酸盐

Target: Proteasome, DPP-4

AGI-41998 tautomers

Cat.No: T64377

Target: Others

Cat.No: T9906

Target: Others

Cat.No: T67837

Synonym: PI4KA inhibitor-F1

Target: PI4K

Cat.No: T3476

Synonym: CGI-1842,JI 101

Target: VEGFR, PDGFR, Ephrin Receptor

Trelagliptin succinate

Cat.No: T2296

Synonym: 曲格列汀琥珀酸盐,琥珀酸曲格列汀,SYR-472 succinate,SYR472

Target: Proteasome, DPP-4

Cat.No: T7133

Synonym: SK-0403,阿拉格列汀

Target: Proteasome, DPP-4

Cat.No: T2677

Synonym: ARO 002,CP-868596

Target: FLT, PDGFR, Autophagy

Cat.No: T24905

Synonym: TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate

Target: Mitochondrial Metabolism

Cat.No: T68053

Synonym: GW823093

Target: DPP-4

4-Aminobenzamidine dihydrochloride

Cat.No: T60248

Synonym: p-Aminobenzamidine dihydrochloride

Target: Serine Protease

Cat.No: T16164

Synonym: N-(3-chlorophenyl)-4-phenylphthalazin-1-amine

Target: PDE

Cat.No: T6900

Target: Histone Methyltransferase

Cat.No: T38507

Synonym: BRL 24924

Target: 5-HT Receptor

CFTR corrector 4

Cat.No: T10776

Target: CFTR

Cat.No: T3188

Target: CCR, Parasite

Cat.No: T12730

Target: RIP kinase

Cat.No: T1766

Synonym: BI 10773,恩格列净

Target: SGLT

Cat.No: T1291

Synonym: 西沙必利,西沙比利,Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase

Target: Potassium Channel, 5-HT Receptor, HER

Ensartinib hydrochloride

Cat.No: T22324

Synonym: Ensartinib dihydrochloride,X-396 dihydrochloride

Target: Others, Trk receptor, c-Met/HGFR, ALK

EGFR-IN-1 hydrochloride

Cat.No: T11157L

Target: EGFR

Cat.No: T0242

Synonym: 西他列汀,MK0431,西格列汀

Target: Proteasome, DPP-4, Autophagy

Cat.No: T50077

Synonym: 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Target: Others

Cat.No: T8970

Target: Ferroptosis, GPX, Glutathione Peroxidase

Cat.No: T1024

Synonym: 罗氟司特,B9302-107,BYK 20869,APTA 2217,BY 217

Target: PDE, RSV

CB2R/FAAH modulator-1

Cat.No: T67896

Target: Cannabinoid Receptor, FAAH

Cat.No: T6611

Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

Target: E1/E2/E3 Enzyme

Cat.No: T16345

Synonym: N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine

Target: Potassium Channel

PKUMDL-LC-101-D04

Cat.No: T36935

Synonym: GPX4-Activator-1d4,PKUMDL-LC-101-D04

Target: GPX

Cat.No: T26132

Synonym: RS-14203,RS14203

Target: Others

Cat.No: T28520

Synonym: SP-2086,SP2086,SP 2086

Target: Others

Besigliptin Tosylate

Cat.No: T26777

Synonym: SHR 117887,SHR-117887,SHR117887

Target: Others

Cat.No: T26857

Target: Others

Cat.No: T15163

Synonym: DPH-153893

Target: Others

4-Chloroloratadine

Cat.No: T20815

Synonym: 4-Chloro loratadine,Loratadine specified impurity C

Target: Others

Cat.No: T26941

Synonym: RO-4876904-001,R1579,RG1579,RO-4876904,R-1579,RG-1579

Target: Others

GLUT4 activator 1

Cat.No: T11420

Target: Others

Cat.No: T11499

Target: Others

Imigliptin Dihydrochloride

Cat.No: T27598

Synonym: Imigliptin

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0314	Hexylresorcinol 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol	Apoptosis; Tyrosinase; Antibacterial; Parasite	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物，具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂，有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。
TN1686	Ginsenoside Rg4 人参皂苷 RG4	Antibacterial	Microbiology/Virology
	Ginsenoside Rg4 是分离自Panax ginsengC. A. Meyer 叶子中的一种人参三醇型人参皂苷。人参三醇型人参皂苷具有多种生物活性，包括防腐，抗糖尿病，伤口愈合，免疫刺激和抗氧化活性等。
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others; Antioxidant	Others; oxidation-reduction
	(+)-pinoresinol-β-D-glucoside; (+)-pinor 是连翘中主要的活性呋喃类木脂素。它显示出抗氧化、降血压和环磷酸腺苷 (cAMP) 磷酸二酯酶抑制活性。
TN1418	Azaleatin 杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮	DPP-4	Proteases/Proteasome
	Azaleatin 是分离自Rhododendron 种中的 O-甲基化黄酮醇。它是二肽基肽酶-IV 的抑制剂。它在 2 型糖尿病和肥胖症中有研究的价值。
T7132	(Rac)-Brassinazole BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑	P450	Metabolism
	(Rac)-Brassinazole 是三唑型化合物，是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T10024	1-Octanol Octanol,正辛醇	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	1-Octanol (Octanol) 是一种饱和脂肪醇，是一种 T 型钙通道抑制剂，对天然 T 电流的IC50为 4 μM。它是一种具有类似柴油特性的极具吸引力的生物燃料。
T2862	Desaminotyrosine Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,对羟基苯丙酸,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid,根皮酸	Others; Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) 是一种与微生物相关的代谢物，通过增强 I 型干扰素信号传导来预防流感。
T16442	PCO371 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) 是口服具有活性的甲状旁腺激素受体 1 的完全激动剂，对 PTHR2 无作用
T8787	Drotaverine hydrochloride	PDE	Metabolism
	Drotaverine hydrochloride 是磷酸二酯酶 4 (PDE4)的抑制剂，也是 L 型电压依赖钙通道(L-VDCC)的阻滞剂，可阻断3',5'-环腺苷单磷酸的降解。它在体内有抗痉挛效果，但无抗胆碱能的效果。
TN1132	Procyanidin A2 原花青素 A2,原花青素A2	IL Receptor; TNF; transporter; Antibacterial	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Procyanidin A2 是一种具有抗癌、抗氧化、抗菌和抗炎活性的黄酮类天然产物，存在于蔓越莓和越橘中。
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮	Others	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone 是来自蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症作用。它能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子表达，降低 C6 细胞磷酸二酯酶活性。它能抑制胶原酶的活性，增加人真皮成纤维细胞新生细胞中 I 型前胶原含量。
T3829	Ginsenoside F3 人参皂苷F3	Others; IFNAR; Interleukin	Immunology/Inflammation; Others
	Ginsenoside F3 是一种皂苷，提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达，有免疫增强的作用。
TN1936	Mogroside III-E 罗汉果皂苷ⅢE	IL Receptor; TNF; TLR	Apoptosis; Immunology/Inflammation
	Mogroside IIIe 是一种葫芦烷型化合物，从罗汉果中分离得到，可抑制 NO 的释放，具有抗肺纤维化作用。
T2S1792	Lycobetaine 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐	Antibacterial	Microbiology/Virology
	Lycobetaine (Ungeremine) 是一种潜在的抗罗克福尔青霉和黑曲霉的生物杀菌剂。它对柱状黄杆菌有很强的抗菌活性。它有效地靶向哺乳动物以及细菌I 型和II 型拓扑异构酶。它显示出强烈的乙酰胆碱酯酶抑制活性（IC(50) 值为 0.35 microM）。它具有抗原生动物活性，在体外试验中对Trypanosoma brucei rhodesiense、T. cruzi 表现出良好的活性。
T4858	4-Hydroxyphenylpyruvic acid 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid	Endogenous Metabolite	Metabolism
	4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物，是一种酶抑制剂。
T4716	Pyrrole-2-carboxylic acid 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite	Metabolism
	Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类，从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
T6S1699	Shogaol [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol	Lipoxygenase; Autophagy	Autophagy; Metabolism
	6-Shogaol (6-Shogaol) 是从生姜中分离的一种天然产物，具有抗癌、抗炎和抗氧化的多种生物活性。
T3S1612	kuwanon G 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G	Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂，具有杀菌作用。
T2S1865	Octyl gallate Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯	Antioxidant; Influenza Virus; Reactive Oxygen Species; Antibacterial; Antifungal; HSV	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction
	Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用，有选择性和敏感性的荧光特性，广泛用作食品添加剂。它对 HSV-1，水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。
T11509	Guanfu base H Atisinium chloride	Others	Others
	Guanfu base H is a diterpenoid alkaloid isolated from Aconitum coreanum. It has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 (IC50s: 4 μM and 3.6 μM).
T83593	(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone
	(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone，这种角型吡喃香豆素类化合物是从Peucedani Radix中分离出的一种天然产物。
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone 1-Methyl-2-undecylquinolin-4(1H)-one	MAO	Metabolism; Neuroscience
	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification ...
T4700	1,3,5-Trihydroxy-4-prenylxanthone
	1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 valu
TN7265	16-epi Latrunculin B	Others	Others
	16-epiLatrunculin B, a stereoisomer of the actin polymerization inhibitor latrunculin B, was initially isolated from the Red Sea sponge N. magnifica. At concentrations of 5-10 µg/ml, it disrupts microfilament activity in actin disruption assays and exhibits cytotoxic effects on mouse KA31T and NIH3T3 tumor cells, with GI50 values of 1 and 4 µg/ml, respectively. Furthermore, it shows antiviral activity against herpes simplex type 1 virus, with an ED50 of 1 µg/ml.
T36845	Isogarcinol	Others	Others
	Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental auto...
T73717	cGAMP diammonium	Others	Others
	cGAMP (Cyclic GMP-AMPP) diammonium 是一种内源性第二信使，通过触发干扰素的产生来响应胞浆 DNA。它通过激活干扰素基因刺激因子（STING），启动信号级联，进而导致I型干扰素及其他免疫介质的生成。
T36563	(E)-Guggulsterone	Others	Others
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy...
T35577	Phosphatidylserines (bovine)	Others	Others
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi...
T37452	Stephacidin B	Others	Others
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...
T35779	Oosporein	Others	Others
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...

天然产物

Hexylresorcinol

Cat.No: T0314

Synonym: 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

Ginsenoside Rg4

Cat.No: TN1686

Synonym: 人参皂苷 RG4

Target: Antibacterial

Pinoresinol 4-O-β-D-glucopyranoside

Cat.No: T4S0792

Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside

Target: Others, Antioxidant

Cat.No: TN1418

Synonym: 杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮

Target: DPP-4

(Rac)-Brassinazole

Cat.No: T7132

Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

Target: P450

Cat.No: T10024

Synonym: Octanol,正辛醇

Target: Calcium Channel, Endogenous Metabolite

Desaminotyrosine

Cat.No: T2862

Synonym: Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,对羟基苯丙酸,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid,根皮酸

Target: Others, Influenza Virus, Endogenous Metabolite

Cat.No: T16442

Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Target: Thyroid hormone receptor(THR)

Drotaverine hydrochloride

Cat.No: T8787

Target: PDE

Cat.No: TN1132

Synonym: 原花青素 A2,原花青素A2

Target: IL Receptor, TNF, transporter, Antibacterial

3,5,6,7,8,3',4'-Heptemthoxyflavone

Cat.No: TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮

Target: Others

Cat.No: T3829

Synonym: 人参皂苷F3

Target: Others, IFNAR, Interleukin

Mogroside III-E

Cat.No: TN1936

Synonym: 罗汉果皂苷ⅢE

Target: IL Receptor, TNF, TLR

Cat.No: T2S1792

Synonym: 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐

Target: Antibacterial

4-Hydroxyphenylpyruvic acid

Cat.No: T4858

Synonym: 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid

Target: Endogenous Metabolite

Pyrrole-2-carboxylic acid

Cat.No: T4716

Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

Cat.No: T6S1699

Synonym: [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol

Target: Lipoxygenase, Autophagy

Cat.No: T3S1612

Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Cat.No: T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

Cat.No: T11509

Synonym: Atisinium chloride

Target: Others

(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone

Cat.No: T83593

1-Methyl-2-undecyl-4(1H)-quinolone

Cat.No: TN2553

Synonym: 1-Methyl-2-undecylquinolin-4(1H)-one

Target: MAO

1,3,5-Trihydroxy-4-prenylxanthone

Cat.No: T4700

16-epi Latrunculin B

Cat.No: TN7265

Target: Others

Cat.No: T36845

Target: Others

cGAMP diammonium

Cat.No: T73717

Target: Others

(E)-Guggulsterone

Cat.No: T36563

Target: Others

Phosphatidylserines (bovine)

Cat.No: T35577

Target: Others

Cat.No: T37452

Target: Others

Cat.No: T35779

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02731	SPINK4 Protein, Mouse, Recombinant (hFc) MPGC60,serine peptidase inhibitor, Kazal type 4...	Mouse	HEK293 Cells
	SPINK4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is O35679.
TMPY-00021	PADI4 Protein, Human, Recombinant (His) PADI5,PAD4,PDI4,peptidyl arginine deiminas...	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase family. PADI4 is expressed in CD34+stem cells in normal tissues, and many more CD34+ cells expressing PADI4 are present in tumour tissues. PADI4 post-translationally converts peptidylarginine to citrulline, a process called citrullination. Studies have demonstrated the high expres...
TMPY-00654	ACVR2B Protein, Human, Recombinant (hFc) activin A receptor, type IIB,HTX4,ActR-IIB...	Human	HEK293 Cells
	ACVR2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.0 kDa and the accession number is Q13705-1.
TMPY-01032	CD299 Protein, Human, Recombinant (hFc) LSIGN,CLEC4M,C-type lectin domain family <...	Human	HEK293 Cells
	CD299 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9H2X3-1.
TMPH-01583	KRT4 Protein, Human, Recombinant (His & SUMO) Keratin, type II cytoskeletal 4,Cytokerati...	Human	E. coli
	N/A. KRT4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.3 kDa and the accession number is P19013.
TMPY-03472	CLEC4F Protein, Rat, Recombinant C-type lectin domain family 4, member F	Rat	HEK293 Cells
	CLEC4F Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 53.7 kDa and the accession number is A6IAN7.
TMPY-00040	CLEC4E Protein, Rhesus, Recombinant (hFc) C-type lectin domain family 4, member E	Rhesus	HEK293 Cells
	CLEC4E Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is XP_001118423.1.
TMPY-05555	CLEC4A Protein, Mouse, Recombinant (His) C-type lectin domain family 4 member A	Mouse	HEK293 Cells
	CLEC4A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.9 kDa and the accession number is Q9QZ15.
TMPY-02915	CLEC4D Protein, Rat, Recombinant (His) C-type lectin domain family 4, member D	Rat	HEK293 Cells
	CLEC4D Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is Q69FH1.
TMPY-03665	CLEC4D Protein, Rat, Recombinant (hFc) C-type lectin domain family 4, member D	Rat	HEK293 Cells
	CLEC4D Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 59 kDa and the accession number is Q69FH1.
TMPY-00176	FNDC4 Protein, Human, Recombinant (mFc) fibronectin type III domain containing 4,F...	Human	HEK293 Cells
	FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of FNDC4 to different immune cell types reveals strong and specific binding to macrophages and monocytes. FNDC4 treatment of bone marrow-derived macrophages in vitro results in reduced phagocytosis, increased cell survival and reduced proinflammatory chemokine expression. Hence, trea...
TMPY-05172	CLEC4A3 Protein, Rat, Recombinant (His) C-type lectin domain family 4, member a3,C...	Rat	HEK293 Cells
	CLEC4A3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is A6ILG4.
TMPY-03475	CLEC4A3 Protein, Rat, Recombinant (hFc) C-type lectin domain family 4, member a3,C...	Rat	HEK293 Cells
	CLEC4A3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.3 kDa and the accession number is Q5YIS0.
TMPY-01052	R-Cadherin/CDH4 Protein, Human, Recombinant (His) R-CAD,cadherin 4, type 1, R-cadherin (reti...	Human	HEK293 Cells
	The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) regions and cytoplasmic domains, that is: classical cadherins, desmosomal cadherins, protocadherins, and cadherin-like molecules. Human cadherin 4, type 1, R-cadherin (retinal), also known as CDH4, CAD4 and RCAD, is a classical cadherin from the cadherin superfamily. It is a calcium-de...
TMPY-03303	CLEC4A2 Protein, Rat, Recombinant (His) Dcir2,C-type lectin domain family 4, membe...	Rat	HEK293 Cells
	CLEC4A2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is Q5YIS1.
TMPY-03873	CLEC4B2 Protein, Rat, Recombinant (His) Aplra1,CLEC4B2,C-type lectin domain family...	Rat	HEK293 Cells
	Clec4b2, also known as mDCAR1, is a member of the DCIR/DCAR family. Expression of Clec4b2 was strongly tissue dependent. Clec4b2 expression on DCs was restricted to the CD8(+) DC subset in spleen and thymus and on subpopulations of CD11b(+) myeloid cells in bone marrow and spleen, whereas the molecule was not detectable on both cell types in lymph nodes and peripheral blood. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune...
TMPH-01698	MORC4 Protein, Human, Recombinant (His & Myc) MORC4,Zinc finger CW-type domain protein <...	Human	E. coli
	Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.
TMPY-05786	SPINK4 Protein, Mouse, Recombinant (His) RP23-28I8.2,serine peptidase inhibitor, Kazal type ...	Mouse	HEK293 Cells
	SPINK4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.11 kDa and the accession number is O35679.
TMPJ-01385	CLEC4E Protein, Human, Recombinant (His) C-Type Lectin Superfamily Member 9,CLEC4E,...	Human	HEK293 Cells
	C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional c...
TMPJ-00532	PADI4 Protein, Human, Recombinant (E. coli, His) PDI5,PADI4,Protein-arginine Deiminase type...	Human	E. coli
	Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune fe...
TMPY-05483	ALK-4/ACVR1B Protein, Human, Recombinant (hFc) ACVRLK4,ACTRIB,ALK4,activin A receptor,	Human	HEK293 Cells
	ALK-4/ACVR1B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36896-1.
TMPY-01293	ALK-4/ACVR1B Protein, Human, Recombinant (His) ACTRIB,ALK4,SKR2,activin A receptor, type ...	Human	HEK293 Cells
	ALK-4/ACVR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is P36896-1.
TMPY-04015	COL9A1 Protein, Human, Recombinant (mFc) DJ149L1.1.2,STL4,collagen, type I...	Human	HEK293 Cells
	COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPY-03960	COL9A1 Protein, Human, Recombinant (His) EDM6,collagen, type IX, α1,STL4,collagen, ...	Human	HEK293 Cells
	COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPH-02610	CLEC4G Protein, Mouse, Recombinant (His) C-type lectin domain family 4 member G,Cle...	Mouse	E. coli
	Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner.
TMPJ-00526	Langerin/CD207 Protein, Human, Recombinant (His) C-type lectin domain family 4 member K,lan...	Human	HEK293 Cells
	Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the epidermis. Langerin is necessary and sufficient for Birbeck granule formation. Human langerin sequence contains a 43 aa cytoplasmic domain, a 21 aa transmembrane domain and a 264 aa extracellular domain (ECD) that contains a coiled-coil domain and a single C-type lectin domain. Hu...
TMPY-01641	CLEC4F Protein, Mouse, Recombinant (hFc) C-type lectin domain family 4, member F,Kc...	Mouse	HEK293 Cells
	CLEC4F Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.1 kDa and the accession number is A0A0R4IZZ5.
TMPJ-01117	INPP5A Protein, Human, Recombinant (His) INPP5A,Type I inositol 1,5-trisphosphate 5-phosphat...	Human	HEK293 Cells
	Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
TMPY-01454	SPINK4 Protein, Human, Recombinant (His) MGC133107,PEC-60,HEL136,PEC60,serine peptidase inhibitor, Ka...	Human	HEK293 Cells
	SPINK4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8 kDa and the accession number is O60575.
TMPH-02611	Langerin/CD207 Protein, Mouse, Recombinant (His) C-type lectin domain family 4 member K,Lan...	Mouse	E. coli
	Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.
TMPH-01065	CCR4 Protein-VLP, Human, Recombinant (His) CC-CKR-4,CCR4,CCR-4,CD194	Human	HEK293 Cells
	High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPH-01064	CCR4 Protein, Human, Recombinant (His & SUMO) CMKBR4,CD194,K5-5,CCR-4,C-C chemo...	Human	E. coli
	High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expressio...
TMPH-01858	PIP4K2B Protein, Human, Recombinant (His) Diphosphoinositide kinase 2-beta,Phosphatidylinositol 5-phos...	Human	E. coli
	PIP4K2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.3 kDa and the accession number is P78356.
TMPY-01051	ACVR2B Protein, Human, Recombinant (His) ActR-IIB,ACTRIIB,activin A receptor, type IIB,HTX	Human	HEK293 Cells
	ACVR2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is Q13705-1.
TMPK-01238	PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated PDI5,Protein-arginine deiminase type-4,HL-...	Human	E. coli
	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinyla...
TMPK-00502	PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated PDI5,HL-60,PAD,PADI5,Protein-arginine deiminase type	Cynomolgus	E. coli
	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biot...
TMPK-00501	PADI4 Protein, Cynomolgus, Recombinant (His) Protein-arginine deiminase type-4,HL60 PAD...	Cynomolgus	E. coli
	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expres...
TMPJ-00501	CLEC3B Protein, Human, Recombinant (His) Plasminogen Kringle 4-Binding Protein,Tetranectin,T...	Human	HEK293 Cells
	C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. In addition, CLEC3B may be involved in the packaging of molecules destined for exocytosis. Also, CLEC3B is best known as a...
TMPJ-01086	CD244 Protein, Mouse, Recombinant (His) NK cell type I receptor protein 2B4,Natura...	Mouse	HEK293 Cells
	Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like domains and at least two cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSMs). 2B4 interacts with CD48, while other SLAM family proteins interact in a homophilic manner. The mouse 2B4 cDNA encodes a 397 amino acid (aa) precursor that includes a 19 aa signal sequence, a ...
TMPH-02239	TMPRSS4 Protein, Human, Recombinant (His & Myc) Channel-activating protease 2,TMPRSS4,Transmembrane...	Human	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. TMPRSS4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10...
TMPJ-01178	TGFBR1 Protein, Mouse, Recombinant (hFc) ALK-5,ALK-5ALK5,TGFβRI,tβR-I,LDS1A,TGFbetaRI,TGFB1R1,activin...	Mouse	HEK293 Cells
	TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models i...
TMPY-01600	CLEC4A Protein, Human, Recombinant (His) CLECSF6,LLIR,CD367,C-type lectin domain family ...	Human	HEK293 Cells
	CLEC4A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is Q9UMR7-1.
TMPY-03270	CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) Ly-5,CD45R,Lyt-4,T200,loc,protein tyrosine...	Mouse	Baculovirus Insect Cells
	CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 108.2 kDa and the accession number is AAA39458.1.
TMPY-03468	CD45 Protein, Mouse, Recombinant (aa 453-1152) loc,Lyt-4,protein tyrosine phosphatase, receptor	Mouse	Baculovirus Insect Cells
	CD45 Protein, Mouse, Recombinant (aa 453-1152) is expressed in Baculovirus insect cells. The predicted molecular weight is 81 kDa and the accession number is AAA39458.1.
TMPY-03726	Dectin-1 Protein, Human, Recombinant (hFc) CANDF4,BGR,DECTIN1,CLECSF12,C-type lectin ...	Human	HEK293 Cells
	Dectin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.1 kDa and the accession number is Q9BXN2-2.
TMPY-00016	Dectin-1 Protein, Human, Recombinant (mFc) CLECSF12,DECTIN1,C-type lectin domain family 7, mem...	Human	HEK293 Cells
	Dectin-1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.1 kDa and the accession number is Q9BXN2-2.
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc) Cd45,protein tyrosine phosphatase, receptor typ...	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-04013	Dectin-1 Protein, Human, Recombinant C-type lectin domain family 7, member A,CLECSF12,DE...	Human	HEK293 Cells
	Dectin-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.5 kDa and the accession number is Q9BXN2-2.
TMPY-01643	CLEC4D Protein, Human, Recombinant (His) CD368,MPCL,Dectin-3,CLEC-6,CLECSF8,C-type lectin do...	Human	HEK293 Cells
	CLEC4D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.2 kDa and the accession number is Q8WXI8.
TMPJ-00405	EphA4 Protein, Human, Recombinant (hFc) Ephrin type-A receptor 4,SEK,hEK8,TYRO1,Ty...	Human	HEK293 Cells
	EphA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P54764.
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重组蛋白

SPINK4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02731

Species: Mouse

Expression System: HEK293 Cells

PADI4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00021

Species: Human

Expression System: Baculovirus Insect Cells

ACVR2B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00654

Species: Human

Expression System: HEK293 Cells

CD299 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01032

Species: Human

Expression System: HEK293 Cells

KRT4 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01583

Species: Human

Expression System: E. coli

CLEC4F Protein, Rat, Recombinant

Cat.No: TMPY-03472

Species: Rat

Expression System: HEK293 Cells

CLEC4E Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-00040

Species: Rhesus

Expression System: HEK293 Cells

CLEC4A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05555

Species: Mouse

Expression System: HEK293 Cells

CLEC4D Protein, Rat, Recombinant (His)

Cat.No: TMPY-02915

Species: Rat

Expression System: HEK293 Cells

CLEC4D Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03665

Species: Rat

Expression System: HEK293 Cells

FNDC4 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00176

Species: Human

Expression System: HEK293 Cells

CLEC4A3 Protein, Rat, Recombinant (His)

Cat.No: TMPY-05172

Species: Rat

Expression System: HEK293 Cells

CLEC4A3 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03475

Species: Rat

Expression System: HEK293 Cells

R-Cadherin/CDH4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01052

Species: Human

Expression System: HEK293 Cells

CLEC4A2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03303

Species: Rat

Expression System: HEK293 Cells

CLEC4B2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03873

Species: Rat

Expression System: HEK293 Cells

MORC4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01698

Species: Human

Expression System: E. coli

SPINK4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05786

Species: Mouse

Expression System: HEK293 Cells

CLEC4E Protein, Human, Recombinant (His)

Cat.No: TMPJ-01385

Species: Human

Expression System: HEK293 Cells

PADI4 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-00532

Species: Human

Expression System: E. coli

ALK-4/ACVR1B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05483

Species: Human

Expression System: HEK293 Cells

ALK-4/ACVR1B Protein, Human, Recombinant (His)

Cat.No: TMPY-01293

Species: Human

Expression System: HEK293 Cells

COL9A1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04015

Species: Human

Expression System: HEK293 Cells

COL9A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03960

Species: Human

Expression System: HEK293 Cells

CLEC4G Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02610

Species: Mouse

Expression System: E. coli

Langerin/CD207 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00526

Species: Human

Expression System: HEK293 Cells

CLEC4F Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01641

Species: Mouse

Expression System: HEK293 Cells

INPP5A Protein, Human, Recombinant (His)

Cat.No: TMPJ-01117

Species: Human

Expression System: HEK293 Cells

SPINK4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01454

Species: Human

Expression System: HEK293 Cells

Langerin/CD207 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02611

Species: Mouse

Expression System: E. coli

CCR4 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01065

Species: Human

Expression System: HEK293 Cells

CCR4 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01064

Species: Human

Expression System: E. coli

PIP4K2B Protein, Human, Recombinant (His)

Cat.No: TMPH-01858

Species: Human

Expression System: E. coli

ACVR2B Protein, Human, Recombinant (His)

Cat.No: TMPY-01051

Species: Human

Expression System: HEK293 Cells

PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-01238

Species: Human

Expression System: E. coli

PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

Cat.No: TMPK-00502

Species: Cynomolgus

Expression System: E. coli

PADI4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00501

Species: Cynomolgus

Expression System: E. coli

CLEC3B Protein, Human, Recombinant (His)

Cat.No: TMPJ-00501

Species: Human

Expression System: HEK293 Cells

CD244 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01086

Species: Mouse

Expression System: HEK293 Cells

TMPRSS4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02239

Species: Human

Expression System: E. coli

TGFBR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01178

Species: Mouse

Expression System: HEK293 Cells

CLEC4A Protein, Human, Recombinant (His)

Cat.No: TMPY-01600

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST)

Cat.No: TMPY-03270

Species: Mouse

Expression System: Baculovirus Insect Cells

CD45 Protein, Mouse, Recombinant (aa 453-1152)

Cat.No: TMPY-03468

Species: Mouse

Expression System: Baculovirus Insect Cells

Dectin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03726

Species: Human

Expression System: HEK293 Cells

Dectin-1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00016

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04277

Species: Mouse

Expression System: HEK293 Cells

Dectin-1 Protein, Human, Recombinant

Cat.No: TMPY-04013

Species: Human

Expression System: HEK293 Cells

CLEC4D Protein, Human, Recombinant (His)

Cat.No: TMPY-01643

Species: Human

Expression System: HEK293 Cells

EphA4 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00405

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0040	3-(4-Hydroxyphenyl)propionic acid-d4 HPPA-d4
	3-(4-Hydroxyphenyl)propionic acid-d4 是 3-(4-Hydroxyphenyl)propionic acid 的氘代化合物。3-(4-Hydroxyphenyl)propionic acid 的 CAS 号为 501-97-3。Desaminotyrosine 是一种与微生物相关的代谢物，通过增强 I 型干扰素信号传导来预防流感。
TMIH-0502	Roflumilast N-Oxide-d4
	Roflumilast N-Oxide-d4 是 Roflumilast N-Oxide 的氘代化合物。Roflumilast N-Oxide 的 CAS 号为 292135-78-5。Roflumilast N-oxide 是一种 PDE 4 型抑制剂。
TMIJ-0131	rac-Valsartan-d9
	rac-Valsartan-d9 是 rac-Valsartan 的氘代化合物。rac-Valsartan 的 CAS 号为 137862-53-4。Valsarta 是一种血管紧张素 II 受体拮抗剂，有用于高血压和心力衰竭的研究潜力。
TMIJ-0120	Donepezil-d5
	Donepezil-d5 是 Donepezil 的氘代化合物。Donepezil 的 CAS 号为 120014-06-4。Donepezil 是一种AChE抑制剂，对牛 AChE 和人 AChE 的IC50分别为 8.12 nM 和 11.6 nM。
TMIH-0399	Norverapamil-d7 HCl
	Norverapamil-d7 HCl 是 Norverapamil HCl 的氘代化合物。Norverapamil HCl 的 CAS 号为 67812-42-4。Norverapamil hydrochloride是 Verapamil 的 N-去甲基代谢物，是L型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T36055	Nitisinone-13C6 Nitisinone-13C6
	Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
TMIH-0087	Amlodipine-d4 Maleate (Racemic)
	Amlodipine-d4 Maleate (Racemic) 是 Amlodipine Maleate (Racemic) 的氘代化合物。Amlodipine Maleate (Racemic) 的 CAS 号为 88150-47-4。Amlodipine maleate是一种具有口服活性的二氢吡啶类钙通道阻滞剂，通过阻滞电压依赖性L型钙通道，从而抑制钙离子内流。Amlodipine maleate可用于研究高血压和癌症。
TMIJ-0205	Glycyrrhetinic acid-d3
	Glycyrrhetinic acid-d3 是 Glycyrrhetinic acid 的氘代化合物。Glycyrrhetinic acid 的 CAS 号为 1449-05-4。Glycyrrhetinic acid是一种饮食衍生的化合物，是NF-kB的抑制剂和蛋白酶体的激活剂，在多细胞生物中起到促进长寿和抗聚集因子的作用。它诱导细胞凋亡。
TMID-0299	Zonisamide-d4
	Zonisamide-d4 是 Zonisamide 的氘代化合物。Zonisamide 的 CAS 号为 68291-97-4。Zonisamide 是锌酶碳酸酐酶 (carbonic anhydrase) 的有效抑制剂，对人类线粒体同工酶 hCA II 和 hCA V 作用的Ki值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性，在癫痫、癫痫发作和帕金森病的研究中具有价值。
TMIJ-0114	Vardenafil-d5
	Vardenafil-d5 是 Vardenafil 的氘代化合物。Vardenafil 的 CAS 号为 224785-90-4。Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...
T35790	Palmitic acid-1,2,3,4-13C4 Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T35775	HT-2 Toxin-13C22 HT-2 Toxin-13C22
	HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...

同位素标记化合物

3-(4-Hydroxyphenyl)propionic acid-d4

Cat.No: TMIH-0040

Synonym: HPPA-d4

Roflumilast N-Oxide-d4

Cat.No: TMIH-0502

rac-Valsartan-d9

Cat.No: TMIJ-0131

Cat.No: TMIJ-0120

Norverapamil-d7 HCl

Cat.No: TMIH-0399

Nitisinone-13C6

Cat.No: T36055

Synonym: Nitisinone-13C6

Amlodipine-d4 Maleate (Racemic)

Cat.No: TMIH-0087

Glycyrrhetinic acid-d3

Cat.No: TMIJ-0205

Cat.No: TMID-0299

Cat.No: TMIJ-0114

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

Palmitic acid-1,2,3,4-13C4

Cat.No: T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

HT-2 Toxin-13C22

Cat.No: T35775

Synonym: HT-2 Toxin-13C22

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